Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	angiogenic sprout fusion	RTN4 SEMA6A	2.75e-05	3	63	2	GO:0120077
GeneOntologyBiologicalProcess	cell adhesion involved in sprouting angiogenesis	RTN4 SEMA6A	2.75e-05	3	63	2	GO:0120078
GeneOntologyBiologicalProcess	canonical Wnt signaling pathway	SOX9 BCL9L APC2 PLEKHA4 BCL9 PRDM15 PPP1CA	8.38e-05	344	63	7	GO:0060070
GeneOntologyCellularComponent	dense body	SND1 PIWIL1	1.86e-04	7	63	2	GO:0097433
Domain	BCL9_beta-catenin-bd_dom	BCL9L BCL9	1.01e-05	2	60	2	IPR024670
Domain	BCL9	BCL9L BCL9	1.01e-05	2	60	2	PF11502
Domain	Bcl-9	BCL9L BCL9	1.01e-05	2	60	2	IPR015668
Domain	RNA_pol_II-bd	PCF11 CHERP	2.11e-04	7	60	2	IPR006903
Domain	CTD_bind	PCF11 CHERP	2.11e-04	7	60	2	PF04818
Domain	RPR	PCF11 CHERP	2.81e-04	8	60	2	SM00582
Domain	CID	PCF11 CHERP	2.81e-04	8	60	2	PS51391
Domain	CID_dom	PCF11 CHERP	2.81e-04	8	60	2	IPR006569
Domain	-	ARID1B ARID3C	1.04e-03	15	60	2	1.10.150.60
Domain	BRIGHT	ARID1B ARID3C	1.04e-03	15	60	2	SM00501
Domain	ARID_dom	ARID1B ARID3C	1.04e-03	15	60	2	IPR001606
Domain	ARID	ARID1B ARID3C	1.04e-03	15	60	2	PS51011
Domain	ARID	ARID1B ARID3C	1.04e-03	15	60	2	PF01388
Domain	ARM-like	ARID1B CLASP1 ARVCF APC2 TARBP1	1.74e-03	270	60	5	IPR011989
Domain	-	PCF11 CHERP	3.14e-03	26	60	2	1.25.40.90
Domain	ENTH_VHS	PCF11 CHERP	3.90e-03	29	60	2	IPR008942
Domain	Arm	ARVCF APC2	4.44e-03	31	60	2	PF00514
Domain	HMGI/Y_DNA-bd_CS	PRB4 PLEKHA4	4.44e-03	31	60	2	IPR000637
Domain	-	ARID1B CLASP1 ARVCF APC2	5.63e-03	222	60	4	1.25.10.10
Domain	ARM_REPEAT	ARVCF APC2	7.32e-03	40	60	2	PS50176
Domain	ARM	ARVCF APC2	7.32e-03	40	60	2	SM00185
Domain	F-box-like	FBXO7 FBXO46	8.80e-03	44	60	2	PF12937
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	PCF11 BCL9L CHERP RBM33 YLPM1 BCL9 POM121C	5.33e-08	180	66	7	35198878
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	PCF11 BCL9L ARID1B CHERP RBM33 YLPM1 BCL9	7.88e-07	268	66	7	33640491
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	PCF11 BCL9L ARID1B RBM33 YLPM1 BCL9 POM121C MAML3	2.46e-06	457	66	8	32344865
Pubmed	The long non-coding RNA rhabdomyosarcoma 2-associated transcript exerts anti-tumor effects on lung adenocarcinoma via ubiquitination of SOX9.	SOX9 FBXO7	3.55e-06	2	66	2	35242855
Pubmed	Structural basis for recognition of arginine methylated Piwi proteins by the extended Tudor domain.	SND1 PIWIL1	3.55e-06	2	66	2	20937909
Pubmed	Targeting BCL9/BCL9L enhances antigen presentation by promoting conventional type 1 dendritic cell (cDC1) activation and tumor infiltration.	BCL9L BCL9	3.55e-06	2	66	2	38811552
Pubmed	Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions.	BCL9L BCL9	3.55e-06	2	66	2	15371335
Pubmed	Bcl9/Bcl9l are critical for Wnt-mediated regulation of stem cell traits in colon epithelium and adenocarcinomas.	BCL9L BCL9	3.55e-06	2	66	2	20682801
Pubmed	BCL9/BCL9L promotes tumorigenicity through immune-dependent and independent mechanisms in triple negative breast cancer.	BCL9L BCL9	3.55e-06	2	66	2	33767438
Pubmed	Mice lacking DYRK2 exhibit congenital malformations with lung hypoplasia and altered Foxf1 expression gradient.	SOX9 CACNA2D2 DYRK1B DYRK3	4.33e-06	57	66	4	34671097
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MYCL SYNRG SBF1 SND1 ARVCF POLG PER1 BCL9 POM121C FBXO46 C6orf132	6.87e-06	1105	66	11	35748872
Pubmed	Increased sensitivity to kindling in mice lacking TSP1.	THBS2 CACNA2D2	1.06e-05	3	66	2	26241338
Pubmed	The genes encoding alpha 2(IX) collagen (COL9A2) map to human chromosome 1p32.3-p33 and mouse chromosome 4.	MYCL COL9A2	1.06e-05	3	66	2	7829066
Pubmed	The interactions of Bcl9/Bcl9L with β-catenin and Pygopus promote breast cancer growth, invasion, and metastasis.	BCL9L BCL9	1.06e-05	3	66	2	34545187
Pubmed	Differential regulation of β-catenin-mediated transcription via N- and C-terminal co-factors governs identity of murine intestinal epithelial stem cells.	BCL9L BCL9	1.06e-05	3	66	2	33649334
Pubmed	Allosteric remodelling of the histone H3 binding pocket in the Pygo2 PHD finger triggered by its binding to the B9L/BCL9 co-factor.	BCL9L BCL9	1.06e-05	3	66	2	20637214
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ILF3 SBF1 CLASP1 ARVCF APC2 YLPM1 DIDO1 FRMPD3 BCL9 PPP1CA	1.31e-05	963	66	10	28671696
Pubmed	Human transcription factor protein interaction networks.	PCF11 HOXA10 SOX9 BCL9L ARID1B RBM33 YLPM1 DIDO1 BCL9 SSBP3 POM121C PPP1CA	1.39e-05	1429	66	12	35140242
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	PCF11 ILF3 RBM33 PAXX YLPM1 DIDO1	1.66e-05	283	66	6	30585729
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	PCF11 ARID1B ILF3 SBF1 SND1 YLPM1 POM121C	2.02e-05	440	66	7	34244565
Pubmed	BCL9 is an essential component of canonical Wnt signaling that mediates the differentiation of myogenic progenitors during muscle regeneration.	BCL9L BCL9	2.12e-05	4	66	2	19699733
Pubmed	LATS2 suppresses oncogenic Wnt signaling by disrupting β-catenin/BCL9 interaction.	BCL9L BCL9	3.53e-05	5	66	2	24360964
Pubmed	TBX3 acts as tissue-specific component of the Wnt/β-catenin transcriptional complex.	BCL9L BCL9	3.53e-05	5	66	2	32808927
Pubmed	Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models.	BCL9L BCL9	3.53e-05	5	66	2	30760710
Pubmed	Crystal structure of a beta-catenin/BCL9/Tcf4 complex.	BCL9L BCL9	3.53e-05	5	66	2	17052462
Pubmed	A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential.	BCL9L BCL9	3.53e-05	5	66	2	19328798
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	PCF11 ARID1B ILF3 CHERP SBF1 CLASP1 TSR1 YLPM1 DIDO1 PPP1CA	3.54e-05	1082	66	10	38697112
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	COL4A3 CLASP1 RBM33 PAXX RTN4 TAPBP PPP1CA	4.39e-05	497	66	7	36774506
Pubmed	PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.	PCF11 ILF3 CHERP TSR1 RTN4 DIDO1	4.63e-05	340	66	6	24332808
Pubmed	BCL9-2 binds Arm/beta-catenin in a Tyr142-independent manner and requires Pygopus for its function in Wg/Wnt signaling.	BCL9L BCL9	5.29e-05	6	66	2	17113272
Pubmed	Expression patterns of cartilage collagens and Sox9 during mouse heart development.	SOX9 COL9A2	5.29e-05	6	66	2	12883905
Pubmed	Loss of BCL9/9l suppresses Wnt driven tumourigenesis in models that recapitulate human cancer.	BCL9L BCL9	5.29e-05	6	66	2	30760720
Pubmed	Role of a BCL9-related beta-catenin-binding protein, B9L, in tumorigenesis induced by aberrant activation of Wnt signaling.	BCL9L BCL9	5.29e-05	6	66	2	15574752
Pubmed	Pax6-dependent, but β-catenin-independent, function of Bcl9 proteins in mouse lens development.	BCL9L BCL9	5.29e-05	6	66	2	25184676
Pubmed	Cloning of the gene for spinocerebellar ataxia 2 reveals a locus with high sensitivity to expanded CAG/glutamine repeats.	ARID1B CHERP	5.29e-05	6	66	2	8896557
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	MYCL HOXA10 SOX9 RNF5 RTN4 DIDO1 KLF17 MAML3	5.81e-05	709	66	8	22988430
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	PCF11 ARID1B ILF3 CHERP CLASP1 TSR1 YLPM1 PER1 PLK4 PPP1CA	6.12e-05	1155	66	10	20360068
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	SYNRG ILF3 SBF1 SND1 RBM33 RTN4 YLPM1 PPP1CA	6.72e-05	724	66	8	36232890
Pubmed	RNA helicase DDX5 acts as a critical regulator for survival of neonatal mouse gonocytes.	SOX9 PIWIL1	7.40e-05	7	66	2	33666296
Pubmed	Mutations in Bcl9 and Pygo genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling.	BCL9L BCL9	7.40e-05	7	66	2	30366904
Pubmed	Type II and type IX collagen transcript isoforms are expressed during mouse testis development.	SOX9 COL9A2	7.40e-05	7	66	2	12606408
Pubmed	Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases.	DYRK1B DYRK3	7.40e-05	7	66	2	9748265
Pubmed	Constitutive scaffolding of multiple Wnt enhanceosome components by Legless/BCL9.	BCL9L BCL9	9.86e-05	8	66	2	28296634
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	PCF11 BCL9L SBF1 SND1 CLASP1 TSR1 RBM33 DIDO1 SSBP3 TAPBP C6orf132	1.10e-04	1497	66	11	31527615
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	PCF11 ILF3 CHERP SND1 CLASP1 YLPM1 PPP1CA	1.18e-04	582	66	7	20467437
Pubmed	The BAF chromatin complex component SMARCC1 does not mediate GLI transcriptional repression of Hedgehog target genes in limb buds.	SOX9 ARID1B	1.27e-04	9	66	2	37805104
Pubmed	Nomenclature of the ARID family of DNA-binding proteins.	ARID1B ARID3C	1.58e-04	10	66	2	15922553
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	APC2 YLPM1 BCL9 POM121C NYAP1 C6orf132	1.68e-04	430	66	6	35044719
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	RBM33 BCL9 SSBP3 PLK4	2.05e-04	152	66	4	38360978
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	ARID1B ARVCF BCL9 POM121C MAML3 TARBP1 FAM149A	2.06e-04	638	66	7	31182584
Pubmed	LncRNA-HIT Functions as an Epigenetic Regulator of Chondrogenesis through Its Recruitment of p100/CBP Complexes.	HOXA10 SND1	2.31e-04	12	66	2	26633036
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	CHERP SBF1 SND1 TSR1 YLPM1 DIDO1 PPP1CA	2.38e-04	653	66	7	22586326
Pubmed	Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis.	ILF3 SND1 PPP1CA DYRK3	2.43e-04	159	66	4	31332168
Pubmed	Aerobic glycolysis tunes YAP/TAZ transcriptional activity.	SND1 TSR1 RTN4 PPP1CA	2.61e-04	162	66	4	25796446
Pubmed	A cytoplasmic role of Wnt/β-catenin transcriptional cofactors Bcl9, Bcl9l, and Pygopus in tooth enamel formation.	BCL9L BCL9	3.18e-04	14	66	2	28174279
Pubmed	Shox2 is required for chondrocyte proliferation and maturation in proximal limb skeleton.	HOXA10 SOX9	3.67e-04	15	66	2	17481601
Pubmed	Setd1b, encoding a histone 3 lysine 4 methyltransferase, is a maternal effect gene required for the oogenic gene expression program.	SOX9 BCL9	3.67e-04	15	66	2	28619824
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	SYNRG ILF3 CHERP SND1 RTN4 YLPM1 DIDO1 POM121C	3.81e-04	934	66	8	33916271
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	ARID1B ILF3 YLPM1 DIDO1 POM121C	4.82e-04	341	66	5	32971831
Pubmed	Gli3 and Plzf cooperate in proximal limb patterning at early stages of limb development.	HOXA10 SOX9	5.32e-04	18	66	2	16015334
Pubmed	Misexpression of Pknox2 in mouse limb bud mesenchyme perturbs zeugopod development and deltoid crest formation.	HOXA10 SOX9	5.32e-04	18	66	2	23717575
Pubmed	Phactr4 regulates neural tube and optic fissure closure by controlling PP1-, Rb-, and E2F1-regulated cell-cycle progression.	SOX9 PPP1CA	5.94e-04	19	66	2	17609112
Pubmed	Oct4 links multiple epigenetic pathways to the pluripotency network.	ILF3 SND1 RTN4 PPP1CA	6.12e-04	203	66	4	22083510
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SYNRG ARID1B SND1 YLPM1 DIDO1 PPP1CA	6.14e-04	549	66	6	38280479
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	PCF11 BCL9L CLASP1 DIDO1 SSBP3	6.23e-04	361	66	5	26167880
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	PCF11 SYNRG ILF3 CLASP1 YLPM1 DIDO1 BCL9	6.56e-04	774	66	7	15302935
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	SSC4D SND1 APC2 PLEKHA4 FBXO7 ADAMTSL4	6.80e-04	560	66	6	21653829
Pubmed	High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.	PCF11 ASB16-AS1 HOXA10 ARVCF TSR1 SSBP3 CLCF1 FBXO46	6.84e-04	1021	66	8	26760575
Pubmed	Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.	COL4A3 SOX9 COL9A2 THBS2	6.95e-04	210	66	4	16537572
Pubmed	The Wilms tumor gene, Wt1, maintains testicular cord integrity by regulating the expression of Col4a1 and Col4a2.	COL4A3 SOX9	7.28e-04	21	66	2	23325811
Pubmed	Proteomics analysis of the estrogen receptor alpha receptosome.	ILF3 SND1 PPP1CA	7.50e-04	93	66	3	20348541
Pubmed	Circular RNA profile in liver tissue of EpCAM knockout mice.	SOX9 PPP1CA	7.99e-04	22	66	2	31524221
Pubmed	C/EBPalpha and beta couple interfollicular keratinocyte proliferation arrest to commitment and terminal differentiation.	MYCL SOX9	7.99e-04	22	66	2	19749746
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PCF11 ARID1B SBF1 ARVCF TSR1 YLPM1 PLK4 PPP1CA	8.15e-04	1049	66	8	27880917
Pubmed	Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.	YLPM1 DIDO1 BCL9 PPP1CA	8.26e-04	220	66	4	24550385
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	COL4A3 ARID1B ILF3 SND1 RTN4 POM121C PPP1CA	8.38e-04	807	66	7	30575818
Pubmed	Pbx1/Pbx2 requirement for distal limb patterning is mediated by the hierarchical control of Hox gene spatial distribution and Shh expression.	HOXA10 SOX9	8.75e-04	23	66	2	16672333
Pubmed	p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas.	SOX9 ARVCF	8.75e-04	23	66	2	25523391
Pubmed	Reprogramming of Sertoli cells to fetal-like Leydig cells by Wt1 ablation.	SOX9 THBS2	8.75e-04	23	66	2	25775596
Pubmed	SOX9-COL9A3-dependent regulation of choroid plexus epithelial polarity governs blood-cerebrospinal fluid barrier integrity.	SOX9 COL9A2	8.75e-04	23	66	2	33526661
Pubmed	Ezh2 is required for neural crest-derived cartilage and bone formation.	HOXA10 SOX9	9.53e-04	24	66	2	24496623
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	PCF11 ILF3 CHERP RBM33 YLPM1	9.76e-04	399	66	5	35987950
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	ILF3 CHERP SND1 TSR1 YLPM1 PPP1CA	1.01e-03	605	66	6	28977666
Pubmed	Characterization of Staufen 1 ribonucleoprotein complexes.	ILF3 PPP1CA	1.03e-03	25	66	2	15303970
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	ARID1B ILF3 CHERP SND1 TSR1 PPP1CA	1.10e-03	615	66	6	31048545
Pubmed	Tbx2 and Tbx3 induce atrioventricular myocardial development and endocardial cushion formation.	SOX9 CACNA2D2	1.12e-03	26	66	2	22130515
Pubmed	Foxp transcription factors suppress a non-pulmonary gene expression program to permit proper lung development.	HOXA10 SOX9	1.12e-03	26	66	2	27341756
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	PCF11 ARID1B ILF3 SND1 CLASP1 RBM33 DIDO1 BCL9	1.12e-03	1103	66	8	34189442
Pubmed	Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	TTBK1 FRMPD3 MAML3	1.13e-03	107	66	3	11347906
Pubmed	Integrative genomic analysis of early neurogenesis reveals a temporal genetic program for differentiation and specification of preplate and Cajal-Retzius neurons.	CACNA2D2 CHST8	1.21e-03	27	66	2	33760820
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	SYNRG SBF1 CLASP1 DYRK1B PLK4 C6orf132 PPP1CA	1.22e-03	861	66	7	36931259
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	MYCL HOXA10 SOX9 SND1 PER1 SSBP3 MAML3	1.35e-03	877	66	7	20211142
Pubmed	Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes.	ILF3 CHERP PPP1CA	1.38e-03	115	66	3	17332742
Pubmed	Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure.	MYCL SOX9	1.49e-03	30	66	2	22980982
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	ARID1B SND1 POM121C	1.68e-03	123	66	3	26912792
Pubmed	EVI1 oncoprotein interacts with a large and complex network of proteins and integrates signals through protein phosphorylation.	ARID1B CHERP PPP1CA	1.88e-03	128	66	3	23858473
Interaction	NUP35 interactions	PCF11 BCL9L ARID1B ILF3 RBM33 YLPM1 PLEKHA4 BCL9 POM121C MAML3	8.40e-07	424	64	10	int:NUP35
Interaction	SP7 interactions	PCF11 HOXA10 BCL9L ARID1B RBM33 YLPM1 BCL9 SSBP3	5.20e-06	304	64	8	int:SP7
Interaction	BCL9L interactions	BCL9L BCL9 SSBP3 PPP1CA	1.62e-05	48	64	4	int:BCL9L
Cytoband	4q28	PLK4 MAML3	7.50e-05	9	67	2	4q28
GeneFamily	AT-rich interaction domain containing	ARID1B ARID3C	4.68e-04	15	39	2	418
GeneFamily	Cyclins\|F-boxes other	FBXO7 FBXO46	3.19e-03	39	39	2	560
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	ARVCF APC2	3.87e-03	43	39	2	409
GeneFamily	Collagens	COL4A3 COL9A2	4.42e-03	46	39	2	490
ToppCell	Hippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3-Excitatory_Neuron.Slc17a7.Nxph3-Sema3c_(Entorhinal_cortex)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	STPG3 PIWIL1 ARID3C C6orf132	1.79e-06	58	67	4	69c0632da1f82800951c11d456a36be9c5abb999
ToppCell	Hippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3-Excitatory_Neuron.Slc17a7.Nxph3-Sema3c_(Entorhinal_cortex)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	STPG3 PIWIL1 ARID3C C6orf132	1.79e-06	58	67	4	c4d5faa29ee606e5682865624f4b5cffda8fb650
Computational	Genes in the cancer module 11.	SOX9 COL9A2 THBS2 CACNA2D2 PRB4 APC2 PER1 BCL9 ITPKA	1.04e-04	540	39	9	MODULE_11
Computational	Genes in the cancer module 66.	SOX9 COL9A2 THBS2 CACNA2D2 PRB4 APC2 PER1 BCL9 ITPKA	1.23e-04	552	39	9	MODULE_66
Computational	Genes in the cancer module 100.	SOX9 COL9A2 THBS2 CACNA2D2 PRB4 APC2 PER1 ITPKA	6.25e-04	544	39	8	MODULE_100
Computational	CNS genes.	SOX9 COL9A2 THBS2 CACNA2D2 PRB4 APC2 PER1 ITPKA	6.40e-04	546	39	8	MODULE_137
Drug	Pantothenic acid calcium salt monohydrate [63409-48-3]; Down 200; 8uM; MCF7; HT_HG-U133A	MYCL PRR4 SBF1 ARVCF POLG BCL9 DYRK3	1.44e-06	196	65	7	3248_DN
Drug	haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A	SOX9 PRR4 SBF1 YLPM1 BCL9 CHST8 DYRK3	1.44e-06	196	65	7	6923_UP
Drug	fluphenazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A	SOX9 SBF1 PRB4 YLPM1 SEMA6A DYRK3	1.66e-05	189	65	6	6954_UP
Drug	aspirin, USP; Up 200; 100uM; MCF7; HT_HG-U133A	SOX9 PRB4 YLPM1 SEMA6A BCL9 DYRK3	2.10e-05	197	65	6	6924_UP
Drug	prochlorperazine dimaleate salt; Down 200; 10uM; PC3; HT_HG-U133A	PCF11 CHERP CLASP1 TSR1 YLPM1 BCL9	2.10e-05	197	65	6	1215_DN
Drug	Testosterone propionate [57-85-2]; Up 200; 11.6uM; MCF7; HT_HG-U133A	MYCL SND1 PER1 BCL9 PLK4 FAM149A	2.16e-05	198	65	6	2649_UP
Drug	Clopamide [636-54-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A	HOXA10 SOX9 SBF1 ARVCF PRB4 APC2	2.22e-05	199	65	6	3220_UP
Drug	chondroitin sulfate	COL4A3 COL9A2 THBS2 CHERP TSR1 RTN4 ADAMTSL4 CHST8	2.24e-05	413	65	8	CID000024766
Disease	Intervertebral disc disorder	COL9A2 THBS2	6.69e-05	6	63	2	C0158252
Disease	Down syndrome (implicated_via_orthology)	DYRK1B DYRK3	4.63e-04	15	63	2	DOID:14250 (implicated_via_orthology)
Disease	Epilepsy	ARID1B CACNA2D2 POLG	1.66e-03	109	63	3	C0014544
Disease	Parkinsonism, Juvenile	POLG FBXO7	1.88e-03	30	63	2	C0752105
Disease	response to candesartan	SYNRG PRR20G	2.00e-03	31	63	2	GO_1901556
Disease	childhood gender nonconformity	SND1 SSBP3	3.83e-03	43	63	2	EFO_0020103
Disease	age at menopause	POLG PIWIL1 DIDO1 TAPBP	3.99e-03	302	63	4	EFO_0004704

Protein segments in the cluster

Peptide	Gene	Start	Entry
EPGPPGGRSLPERFQ	ARVCF	241	O00192
HPEALLPRGQGPRPQ	ADAMTSL4	91	Q6UY14
PQPPGNLGAAPRGVF	CACNA2D2	946	Q9NY47
ETGLLRAPPGPRGNP	COL4A3	1171	Q01955
GLAGPPPRGAQDPAL	ARID3C	236	A6NKF2
PGPQRYPIGIQGRTP	ARID1B	636	Q8NFD5
PQRGPRNAAAARPGP	ASB16-AS1	51	Q495Z4
PGTGAQLPPQPRYLG	DYRK1B	536	Q9Y463
RPAVGPQRFPGPPEF	RBM33	411	Q96EV2
AGPQLFLPDPDPQRG	PAXX	156	Q9BUH6
GPRAPGRAPNQPRVD	DDI1	81	Q8WTU0
TPGQAPPRPGNGYLL	MAML3	426	Q96JK9
PRNPLQPGPGERELG	FAM149A	141	A5PLN7
IRGGPDRDPGPRYQP	PER1	301	O15534
RGLPGFLPGAPDPDQ	PLSCR5	11	A0PG75
EPPPPGQLFFLQNRG	FBXO46	401	Q6PJ61
GQLFFLQNRGPDGPP	FBXO46	406	Q6PJ61
FPAQPPGRGFDLPPA	HOXA10	241	P31260
RRGGQVPNGLPRAPP	ITPKA	61	P23677
NGGPPDPGFLRPQRA	SBF1	1311	O95248
PAPAPEGQDLRNRPG	POM121C	136	A8CG34
HGQPGPRFERTPGQP	PCF11	1056	O94913
PRFERTPGQPGPQRF	PCF11	1061	O94913
GLNPGGRPITPPRNS	PPP1CA	311	P62136
RQLPNAGPGAPPALG	C6orf132	1021	Q5T0Z8
YRPQPGDEGPGRTPQ	DNAJC25	81	Q9H1X3
RPVGLGPGPNPNLRS	DERPC	201	P0CG12
RASGPLGPNPANFPR	DERPC	401	P0CG12
LQGPPRDQPGGPAGR	APC2	1411	O95996
GGGQREPPFRMQRPP	CHERP	506	Q8IWX8
PNPILPGRGGPNDRF	FBXO7	491	Q9Y3I1
GQSPGPPGARRKLPQ	FRMPD3	881	Q5JV73
VPKIPDGRNFPPGQG	BCL9	596	O00512
FPGEGPLGRPSNLPQ	BCL9	1171	O00512
ALAQIRGPPGERGPP	COL9A2	21	Q14055
NEVPPPPNLRGRGRG	ILF3	631	Q12906
PPFPGPRFPGNQIQR	BCL9L	596	Q86UU0
IASNDGPRGPPPARF	DIDO1	1786	Q9BTC0
EGPRGQAPNFMPGPR	DIDO1	1946	Q9BTC0
RAPGPRGDGQQPPLG	MAPKAPK5-AS1	41	Q8N8E1
PFGGNLRMPPNGLPV	KLF17	146	Q5JT82
KDAGPPGAGLPPQQR	DYRK3	11	O43781
PEGRRPQGGNQPQRP	PRB4	36	P10163
PPQGSGQPRGERELP	NYAP1	411	Q6ZVC0
RPQPPPAEGELFGRG	PIWIL1	36	Q96J94
FGNDFVPPAPRGPLP	RTN4	81	Q9NQC3
RGAAPAAPLRGQPGP	POLG	141	A0A3B3IS91
YAGGPRPPIRMGNQP	SSBP3	156	Q9BWW4
PRPQGQRPAPESRGG	RNF5	96	Q99942
LGQAPFLGMRPPGPQ	SYNRG	96	Q9UMZ2
GDDYGQPRSPARPQP	PLEKHA4	156	Q9H4M7
GLRRNPALPPGPFAQ	PRDM15	171	P57071
PPARAQPAPPAGRGQ	PRR20G	56	P0DPQ3
LNNAPRGSAAPGPPR	SHISA8	226	B8ZZ34
RGQPRGGPPPERQIN	SND1	36	Q7KZF4
QRPGVPAGPRPLDGY	ST6GALNAC5	66	Q9BVH7
GRPLPEGGRQPPIDF	SOX9	256	P48436
PNGGRGFPLADRPPS	PLK4	651	O00444
SGAPRGRNLPAPDQP	CHST8	81	Q9H2A9
GPPFNEPDFNPPRLG	CLCF1	66	Q9UBD9
PPLDRFGLGQPGRIP	CLASP1	771	Q7Z460
QIDAPGDPFPLNPRG	TSR1	301	Q2NL82
LGPGRAQAGARPPAP	TTBK1	1216	Q5TCY1
DRLAPGAPRGNPPKA	MYCL	111	P12524
PVPRPLAFGQGRGPI	SSC4D	106	Q8WTU2
GLPRGFPRPPLGLGA	STPG3	331	Q8N7X2
QSFGRGDNPPPAPQR	SEMA6A	951	Q9H2E6
RPGALLLRQGPGEPP	TAPBP	41	O15533
EGPRPKGPRFEGNRP	YLPM1	776	P49750
KGPRFEGNRPDGPRP	YLPM1	781	P49750
PEGLLPRPPGDSGNQ	PRR4	51	Q16378
LRGRPAGGPDPSLQP	TARBP1	76	Q13395
PCPPRYRGNQPVGVG	THBS2	621	P35442