Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH2 DNAH5 DYNC1H1

8.08e-0518953GO:0008569
GeneOntologyMolecularFunctionactin binding

SPTBN4 MYH6 SYNE3 DST SYNE1 ESPNL MACF1 DMD MYO18B UTRN

9.39e-054799510GO:0003779
GeneOntologyMolecularFunctionactin filament binding

SPTBN4 MYH6 SYNE3 SYNE1 ESPNL MACF1 MYO18B

1.06e-04227957GO:0051015
GeneOntologyMolecularFunctioncytoskeleton-nuclear membrane anchor activity

SYNE3 SYNE1

2.22e-045952GO:0140444
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYH6 DNAH2 MYO18B DNAH5 DYNC1H1

2.51e-04118955GO:0003774
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH2 DNAH5 DYNC1H1

3.14e-0428953GO:0051959
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH2 DNAH5 DYNC1H1

7.21e-0437953GO:0045505
GeneOntologyMolecularFunctionATP hydrolysis activity

DNAH2 MACF1 DHX33 DNAH5 ABCA9 ABCG5 DYNC1H1 HSP90AA4P

1.21e-03441958GO:0016887
GeneOntologyMolecularFunctionprotein-membrane adaptor activity

SPTBN4 SYNE3 SYNE1

1.28e-0345953GO:0043495
GeneOntologyMolecularFunctiondipeptidyl-peptidase activity

DPP4 DPP10

1.43e-0312952GO:0008239
GeneOntologyBiologicalProcessresponse to curcumin

PLCG1 ITGAM

2.10e-052952GO:1904643
GeneOntologyBiologicalProcessaxonemal dynein complex assembly

ODAD1 DNAH2 CCDC65 DNAH5

3.75e-0541954GO:0070286
GeneOntologyBiologicalProcessregulation of peptidyl-serine phosphorylation

SPTBN4 AKAP9 PPM1F SH2D3C FNIP1 DMD

4.12e-05137956GO:0033135
GeneOntologyBiologicalProcessnucleus localization

SYNE3 SYNE1 DMD DYNC1H1

4.98e-0544954GO:0051647
GeneOntologyBiologicalProcessregulation of mesenchymal cell apoptotic process

MSX1 MSX2 SYNE1

6.14e-0517953GO:2001053
GeneOntologyBiologicalProcessregionalization

MSX1 MSX2 IFT140 SOSTDC1 VAX2 DLX2 PAX7 EMX1 ITGAM DNAH5

7.07e-054789510GO:0003002
GeneOntologyBiologicalProcessmesenchymal cell apoptotic process

MSX1 MSX2 SYNE1

8.69e-0519953GO:0097152
GeneOntologyBiologicalProcessradial glial cell differentiation

METTL3 EMX1 CDH2

1.02e-0420953GO:0060019
GeneOntologyBiologicalProcesspositive regulation of mesenchymal cell apoptotic process

MSX1 MSX2

1.25e-044952GO:2001055
GeneOntologyBiologicalProcessembryonic nail plate morphogenesis

MSX1 MSX2

1.25e-044952GO:0035880
GeneOntologyBiologicalProcesspattern specification process

MSX1 MSX2 IFT140 SOSTDC1 VAX2 DLX2 PAX7 EMX1 ITGAM DNAH5

1.55e-045269510GO:0007389
GeneOntologyCellularComponentdynein complex

ODAD1 DNAH2 CCDC65 DNAH5 DYNC1H1

4.39e-0654945GO:0030286
GeneOntologyCellularComponentaxonemal dynein complex

ODAD1 DNAH2 CCDC65 DNAH5

4.51e-0625944GO:0005858
GeneOntologyCellularComponentruffle membrane

SH2D3C MACF1 PLCG1 PLEK ARHGEF2 WWC1

9.31e-06108946GO:0032587
GeneOntologyCellularComponentcell leading edge

DPP4 DST SH2D3C MACF1 PLCG1 DMD PLEK ARHGEF2 MCF2L CDH2 WWC1

1.52e-055009411GO:0031252
GeneOntologyCellularComponentleading edge membrane

DPP4 SH2D3C MACF1 PLCG1 PLEK ARHGEF2 WWC1

4.57e-05210947GO:0031256
GeneOntologyCellularComponentcell projection membrane

DPP4 SH2D3C MACF1 PLCG1 DMD PLEK ARHGEF2 UTRN WWC1

1.40e-04431949GO:0031253
GeneOntologyCellularComponentruffle

SH2D3C MACF1 PLCG1 PLEK ARHGEF2 WWC1

3.37e-04206946GO:0001726
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

IFT140 DST ODAD1 DNAH2 CCDC65 DNAH5 DYNC1H1

5.72e-04317947GO:0032838
GeneOntologyCellularComponentmicrotubule associated complex

ODAD1 DNAH2 CCDC65 DNAH5 DYNC1H1

8.05e-04161945GO:0005875
GeneOntologyCellularComponentmicrotubule organizing center attachment site

SYNE3 SYNE1

1.07e-0311942GO:0034992
GeneOntologyCellularComponentmeiotic nuclear membrane microtubule tethering complex

SYNE3 SYNE1

1.07e-0311942GO:0034993
GeneOntologyCellularComponentnuclear membrane protein complex

SYNE3 SYNE1

1.07e-0311942GO:0106083
GeneOntologyCellularComponentnuclear membrane microtubule tethering complex

SYNE3 SYNE1

1.07e-0311942GO:0106094
GeneOntologyCellularComponentcytoplasmic region

IFT140 DST ODAD1 DNAH2 CCDC65 DNAH5 DYNC1H1

1.20e-03360947GO:0099568
GeneOntologyCellularComponentouter dynein arm

ODAD1 DNAH5

1.28e-0312942GO:0036157
GeneOntologyCellularComponentmyosin complex

MYH6 MYH16 MYO18B

2.39e-0359943GO:0016459
GeneOntologyCellularComponentaxoneme

IFT140 ODAD1 DNAH2 CCDC65 DNAH5

2.44e-03207945GO:0005930
GeneOntologyCellularComponentciliary plasm

IFT140 ODAD1 DNAH2 CCDC65 DNAH5

2.49e-03208945GO:0097014
DomainSpectrin

SPTBN4 SYNE3 DST DRP2 SYNE1 MACF1 DMD MCF2L UTRN

7.97e-1623919PF00435
DomainSpectrin_repeat

SPTBN4 SYNE3 DST DRP2 SYNE1 MACF1 DMD MCF2L UTRN

9.53e-1529919IPR002017
DomainSpectrin/alpha-actinin

SPTBN4 SYNE3 DST DRP2 SYNE1 MACF1 DMD MCF2L UTRN

2.64e-1432919IPR018159
DomainSPEC

SPTBN4 SYNE3 DST DRP2 SYNE1 MACF1 DMD MCF2L UTRN

2.64e-1432919SM00150
DomainHomeobox_metazoa

MSX1 MSX2 BARHL1 HMX3 NKX1-1 VAX2 DLX2 HMX1 EMX1 NKX1-2

1.89e-11909110IPR020479
DomainHomeobox_CS

MSX1 MSX2 BARHL1 HMX3 NKX1-1 VAX2 DLX2 PAX7 HMX1 EMX1 HOXB13 NKX1-2

1.06e-101869112IPR017970
DomainActinin_actin-bd_CS

SPTBN4 DST SYNE1 MACF1 DMD UTRN

1.07e-0923916IPR001589
DomainACTININ_2

SPTBN4 DST SYNE1 MACF1 DMD UTRN

1.07e-0923916PS00020
DomainACTININ_1

SPTBN4 DST SYNE1 MACF1 DMD UTRN

1.07e-0923916PS00019
DomainHomeobox

MSX1 MSX2 BARHL1 HMX3 NKX1-1 VAX2 DLX2 PAX7 HMX1 EMX1 HOXB13 NKX1-2

1.49e-092349112PF00046
DomainHOMEOBOX_1

MSX1 MSX2 BARHL1 HMX3 NKX1-1 VAX2 DLX2 PAX7 HMX1 EMX1 HOXB13 NKX1-2

1.64e-092369112PS00027
DomainHOX

MSX1 MSX2 BARHL1 HMX3 NKX1-1 VAX2 DLX2 PAX7 HMX1 EMX1 HOXB13 NKX1-2

1.72e-092379112SM00389
DomainHOMEOBOX_2

MSX1 MSX2 BARHL1 HMX3 NKX1-1 VAX2 DLX2 PAX7 HMX1 EMX1 HOXB13 NKX1-2

1.89e-092399112PS50071
DomainHomeobox_dom

MSX1 MSX2 BARHL1 HMX3 NKX1-1 VAX2 DLX2 PAX7 HMX1 EMX1 HOXB13 NKX1-2

1.89e-092399112IPR001356
DomainHTH_motif

MSX1 MSX2 BARHL1 VAX2 DLX2 HMX1 EMX1

4.35e-0869917IPR000047
DomainHomeodomain-like

MSX1 MSX2 BARHL1 HMX3 NKX1-1 VAX2 DLX2 PAX7 HMX1 EMX1 HOXB13 NKX1-2

7.33e-083329112IPR009057
Domain-

MSX1 MSX2 BARHL1 HMX3 VAX2 DLX2 PAX7 HMX1 EMX1 HOXB13 NKX1-2

1.29e-0728391111.10.10.60
DomainCH

SPTBN4 DST SYNE1 MACF1 DMD UTRN

7.42e-0765916SM00033
DomainCH

SPTBN4 DST SYNE1 MACF1 DMD UTRN

1.16e-0670916PF00307
Domain-

SPTBN4 DST SYNE1 MACF1 DMD UTRN

1.26e-06719161.10.418.10
DomainCH

SPTBN4 DST SYNE1 MACF1 DMD UTRN

1.48e-0673916PS50021
DomainCH-domain

SPTBN4 DST SYNE1 MACF1 DMD UTRN

1.74e-0675916IPR001715
DomainEF-hand_dom_typ1

DRP2 DMD UTRN

2.21e-066913IPR015153
DomainEF-hand_dom_typ2

DRP2 DMD UTRN

2.21e-066913IPR015154
DomainEF-hand_2

DRP2 DMD UTRN

2.21e-066913PF09068
DomainEF-hand_3

DRP2 DMD UTRN

2.21e-066913PF09069
DomainWW

DRP2 HECW2 DMD UTRN WWC1

3.21e-0647915PF00397
DomainWW

DRP2 HECW2 DMD UTRN WWC1

3.57e-0648915SM00456
DomainWW_DOMAIN_2

DRP2 HECW2 DMD UTRN WWC1

4.84e-0651915PS50020
DomainWW_DOMAIN_1

DRP2 HECW2 DMD UTRN WWC1

4.84e-0651915PS01159
DomainWW_dom

DRP2 HECW2 DMD UTRN WWC1

5.33e-0652915IPR001202
DomainDHC_N1

DNAH2 DNAH5 DYNC1H1

6.16e-068913PF08385
DomainDynein_heavy_dom-1

DNAH2 DNAH5 DYNC1H1

6.16e-068913IPR013594
DomainDystrophin

DMD UTRN

2.35e-052912IPR016344
DomainDynein_heavy_chain_D4_dom

DNAH2 DNAH5 DYNC1H1

3.92e-0514913IPR024317
DomainDynein_HC_stalk

DNAH2 DNAH5 DYNC1H1

3.92e-0514913IPR024743
DomainDynein_heavy_dom-2

DNAH2 DNAH5 DYNC1H1

3.92e-0514913IPR013602
DomainDHC_N2

DNAH2 DNAH5 DYNC1H1

3.92e-0514913PF08393
DomainMT

DNAH2 DNAH5 DYNC1H1

3.92e-0514913PF12777
DomainAAA_8

DNAH2 DNAH5 DYNC1H1

3.92e-0514913PF12780
DomainATPase_dyneun-rel_AAA

DNAH2 DNAH5 DYNC1H1

3.92e-0514913IPR011704
DomainAAA_5

DNAH2 DNAH5 DYNC1H1

3.92e-0514913PF07728
DomainDHC_fam

DNAH2 DNAH5 DYNC1H1

4.88e-0515913IPR026983
DomainDynein_heavy_dom

DNAH2 DNAH5 DYNC1H1

4.88e-0515913IPR004273
DomainDynein_heavy

DNAH2 DNAH5 DYNC1H1

4.88e-0515913PF03028
DomainPH

SPTBN4 OSBPL8 PHLPP1 PLCG1 PLEK ARHGEF2 MCF2L TECPR1

6.36e-05278918SM00233
DomainPH_DOMAIN

SPTBN4 OSBPL8 PHLPP1 PLCG1 PLEK ARHGEF2 MCF2L TECPR1

6.53e-05279918PS50003
DomainPH_domain

SPTBN4 OSBPL8 PHLPP1 PLCG1 PLEK ARHGEF2 MCF2L TECPR1

6.69e-05280918IPR001849
DomainZZ

DRP2 DMD UTRN

8.66e-0518913PF00569
DomainZF_ZZ_2

DRP2 DMD UTRN

8.66e-0518913PS50135
DomainZF_ZZ_1

DRP2 DMD UTRN

8.66e-0518913PS01357
DomainZnf_ZZ

DRP2 DMD UTRN

1.02e-0419913IPR000433
DomainZnF_ZZ

DRP2 DMD UTRN

1.02e-0419913SM00291
Domain-

SPTBN4 OSBPL8 PHLPP1 PLCG1 PLEK ARHGEF2 MCF2L RGS3 TECPR1

1.22e-043919192.30.29.30
DomainPH

SPTBN4 OSBPL8 PHLPP1 PLCG1 PLEK ARHGEF2 MCF2L

1.28e-04229917PF00169
DomainKASH

SYNE3 SYNE1

1.40e-044912PF10541
DomainKASH

SYNE3 SYNE1

1.40e-044912IPR012315
DomainKASH

SYNE3 SYNE1

1.40e-044912PS51049
DomainKASH

SYNE3 SYNE1

1.40e-044912SM01249
DomainPH_dom-like

SPTBN4 OSBPL8 PHLPP1 PLCG1 PLEK ARHGEF2 MCF2L RGS3 TECPR1

2.31e-04426919IPR011993
Domain-

RASGRP1 DST DRP2 MACF1 PLCG1 DMD UTRN

2.86e-042619171.10.238.10
Domain-

DPP4 DPP10

3.48e-0469122.140.10.30
Domain-

DST MACF1

3.48e-0469123.90.1290.10
DomainDPPIV_N

DPP4 DPP10

3.48e-046912PF00930
DomainGAR

DST MACF1

3.48e-046912PS51460
Domain-

DST MACF1

3.48e-0469123.30.920.20
DomainGAS_dom

DST MACF1

3.48e-046912IPR003108
DomainPeptidase_S9B_N

DPP4 DPP10

3.48e-046912IPR002469
DomainGAS2

DST MACF1

3.48e-046912PF02187
DomainGAS2

DST MACF1

3.48e-046912SM00243
DomainPlectin_repeat

DST MACF1

4.85e-047912IPR001101
DomainPlectin

DST MACF1

4.85e-047912PF00681
DomainPLEC

DST MACF1

4.85e-047912SM00250
DomainEF-hand-dom_pair

RASGRP1 DST DRP2 MACF1 PLCG1 DMD UTRN

5.06e-04287917IPR011992
DomainAAA+_ATPase

DNAH2 DNAH5 ABCA9 ABCG5 DYNC1H1

6.94e-04144915IPR003593
DomainAAA

DNAH2 DNAH5 ABCA9 ABCG5 DYNC1H1

6.94e-04144915SM00382
DomainPeptidase_S9

DPP4 DPP10

1.25e-0311912PF00326
DomainPeptidase_S9

DPP4 DPP10

1.25e-0311912IPR001375
DomainPP2C

PPM1F PHLPP1

3.80e-0319912PF00481
DomainMyosin-like_IQ_dom

MYH6 MYO18B

3.80e-0319912IPR027401
Domain-

MYH6 MYO18B

3.80e-03199124.10.270.10
DomainC2

HECW2 PLCG1 RGS3 WWC1

3.86e-03131914PF00168
DomainPP2Cc

PPM1F PHLPP1

4.21e-0320912SM00332
DomainPPM-type_phosphatase_dom

PPM1F PHLPP1

4.21e-0320912IPR001932
Domain-

PPM1F PHLPP1

4.21e-03209123.60.40.10
DomainPPM_2

PPM1F PHLPP1

4.21e-0320912PS51746
DomainButyrophylin

TRIM34 TRIM16L TRIM48

4.84e-0370913IPR003879
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

DST AKAP9 SYNE1 MACF1 DMD UTRN CCDC136 DYNC1H1 WWC1

4.05e-1015196917043677
Pubmed

HENA, heterogeneous network-based data set for Alzheimer's disease.

DST AKAP9 SYNE1 MACF1 PLCG1 DMD DYNC1H1

4.51e-0812096731413325
Pubmed

Patterning of the murine dentition by homeobox genes.

MSX1 MSX2 DLX2

8.14e-0849639541203
Pubmed

Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.

DST MACF1 DMD

8.14e-0849638954775
Pubmed

14-3-3 interacts with regulator of G protein signaling proteins and modulates their activity.

MSX1 YWHAB RGS3

2.03e-07596310862767
Pubmed

Specific disruption of a schwann cell dystrophin-related protein complex in a demyelinating neuropathy.

DRP2 DMD UTRN

2.03e-07596311430802
Pubmed

Postnatal lethality in mice lacking the Sax2 homeobox gene homologous to Drosophila S59/slouch: evidence for positive and negative autoregulation.

NKX1-1 HMX1 CDH2 NKX1-2

3.84e-072296414645517
Pubmed

Heterodimerization of Msx and Dlx homeoproteins results in functional antagonism.

MSX1 MSX2 DLX2

4.05e-0769639111364
Pubmed

Variation of tooth number in mammalian dentition: connecting genetics, development, and evolution.

MSX1 MSX2 DLX2

4.05e-07696312752768
Pubmed

Expression of the dystrophin-related protein 2 (Drp2) transcript in the mouse.

DRP2 DMD UTRN

4.05e-0769639245586
Pubmed

Developmental regulation of gonadotropin-releasing hormone gene expression by the MSX and DLX homeodomain protein families.

MSX1 MSX2 DLX2

4.05e-07696315743757
Pubmed

Inactivation of Sirt6 ameliorates muscular dystrophy in mdx mice by releasing suppression of utrophin expression.

PAX7 DMD UTRN

4.05e-07696335859073
Pubmed

Contribution of the different modules in the utrophin carboxy-terminal region to the formation and regulation of the DAP complex.

DRP2 DMD UTRN

4.05e-07696310767429
Pubmed

The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development.

MSX1 MSX2 MYH6 CDH2

5.55e-072496410021345
Pubmed

Wnt signaling determines ventral spinal cord cell fates in a time-dependent manner.

MSX1 MSX2 PAX7 CDH2

6.59e-072596418927156
Pubmed

A signaling cascade involving endothelin-1, dHAND and msx1 regulates development of neural-crest-derived branchial arch mesenchyme.

MSX1 MSX2 DLX2

7.08e-0779639671575
Pubmed

Restriction of BMP4 activity domains in the developing neural tube of the mouse embryo.

MSX1 MSX2 PAX7

7.08e-07796315218525
Pubmed

Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.

MSX1 MSX2 BARHL1 HMX3 PAX7 HMX1 HOXB13 NKX1-2

7.18e-0726396820932939
Pubmed

Roles for Msx and Dlx homeoproteins in vertebrate development.

MSX1 MSX2 DLX2

1.13e-06896310773441
Pubmed

Interactions between BMP-7 and USAG-1 (uterine sensitization-associated gene-1) regulate supernumerary organ formations.

MSX1 SOSTDC1 DLX2

1.69e-06996324816837
Pubmed

Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate.

MSX1 MSX2 PAX7 DMD

2.37e-063496431024170
Pubmed

Genomic Resolution of DLX-Orchestrated Transcriptional Circuits Driving Development of Forebrain GABAergic Neurons.

NRXN3 DLX2 PAX7

2.41e-061096331433982
Pubmed

Distal-less and other homeobox genes in the development of the dentition.

MSX1 MSX2 DLX2

2.41e-06109637964557
Pubmed

Dlx and other homeobox genes in the morphological development of the dentition.

MSX1 MSX2 DLX2

2.41e-06109637554933
Pubmed

Zic1 promotes the expansion of dorsal neural progenitors in spinal cord by inhibiting neuronal differentiation.

MSX1 MSX2 PAX7

3.31e-061196311944941
Pubmed

Msx1 is required for dorsal diencephalon patterning.

MSX1 MSX2 PAX7

3.31e-061196312874124
Pubmed

gamma-Syntrophin scaffolding is spatially and functionally distinct from that of the alpha/beta syntrophins.

DRP2 DMD UTRN

3.31e-061196316857187
Pubmed

Comparative gene expression analysis of genital tubercle development reveals a putative appendicular Wnt7 network for the epidermal differentiation.

MSX1 MSX2 SOSTDC1 TRPM1

3.36e-063796420510229
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

DST SYNE1 SNX25 MACF1 EEA1 DMD DNAH5

4.09e-0623496736243803
Pubmed

Pax3 and Pax7 play essential safeguard functions against environmental stress-induced birth defects.

MSX1 DLX2 PAX7

4.40e-061296325800090
Pubmed

Jumonji, a nuclear protein that is necessary for normal heart development.

MSX1 MSX2 MYH6

4.40e-061296310807864
Pubmed

Lrp6-mediated canonical Wnt signaling is required for lip formation and fusion.

MSX1 MSX2 SOSTDC1

4.40e-061296319700620
Pubmed

Enhanced BMP signaling results in supernumerary tooth formation in USAG-1 deficient mouse.

MSX1 SOSTDC1 DLX2

5.71e-061396318329379
Pubmed

Genetic dissection of Pitx2 in craniofacial development uncovers new functions in branchial arch morphogenesis, late aspects of tooth morphogenesis and cell migration.

MSX1 MSX2 DLX2

5.71e-061396314623826
Pubmed

Graded phenotypic response to partial and complete deficiency of a brain-specific transcript variant of the winged helix transcription factor RFX4.

MSX2 DLX2 EMX1

5.71e-061396312925582
Pubmed

Wnt/beta-catenin signaling directs multiple stages of tooth morphogenesis.

MSX1 MSX2 SOSTDC1

7.26e-061496318022614
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH2 DNAH5 DYNC1H1

7.26e-06149639373155
Pubmed

Decreased myocardial nNOS, increased iNOS and abnormal ECGs in mouse models of Duchenne muscular dystrophy.

DMD UTRN

7.54e-06296210525423
Pubmed

Insertional mutation of the mouse Msx1 homeobox gene by an nlacZ reporter gene.

MSX1 MSX2

7.54e-0629629256350
Pubmed

In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice.

DMD UTRN

7.54e-06296228790199
Pubmed

Metabolic dysfunction and altered mitochondrial dynamics in the utrophin-dystrophin deficient mouse model of duchenne muscular dystrophy.

DMD UTRN

7.54e-06296225859846
Pubmed

Msx1 and Msx2 gene expression is downregulated in the cadmium-induced omphalocele in the chick model.

MSX1 MSX2

7.54e-06296220620318
Pubmed

G-utrophin, the autosomal homologue of dystrophin Dp116, is expressed in sensory ganglia and brain.

DMD UTRN

7.54e-0629627731967
Pubmed

Role of dystrophin and utrophin for assembly and function of the dystrophin glycoprotein complex in non-muscle tissue.

DMD UTRN

7.54e-06296216710609
Pubmed

Nonclinical Exon Skipping Studies with 2'-O-Methyl Phosphorothioate Antisense Oligonucleotides in mdx and mdx-utrn-/- Mice Inspired by Clinical Trial Results.

DMD UTRN

7.54e-06296230672725
Pubmed

Ventral abdominal wall dysmorphogenesis of Msx1/Msx2 double-mutant mice.

MSX1 MSX2

7.54e-06296215803476
Pubmed

Talin, vinculin and DRP (utrophin) concentrations are increased at mdx myotendinous junctions following onset of necrosis.

DMD UTRN

7.54e-0629627962191
Pubmed

Does utrophin expression in muscles of mdx mice during postnatal development functionally compensate for dystrophin deficiency?

DMD UTRN

7.54e-0629628021701
Pubmed

Correlation of Utrophin Levels with the Dystrophin Protein Complex and Muscle Fibre Regeneration in Duchenne and Becker Muscular Dystrophy Muscle Biopsies.

DMD UTRN

7.54e-06296226974331
Pubmed

Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.

DST MACF1

7.54e-06296211002341
Pubmed

Androgen receptor agonists increase lean mass, improve cardiopulmonary functions and extend survival in preclinical models of Duchenne muscular dystrophy.

DMD UTRN

7.54e-06296228453658
Pubmed

A quantitative study of bioenergetics in skeletal muscle lacking utrophin and dystrophin.

DMD UTRN

7.54e-06296211801396
Pubmed

Apo-dystrophin-1 and apo-dystrophin-2, products of the Duchenne muscular dystrophy locus: expression during mouse embryogenesis and in cultured cell lines.

DMD UTRN

7.54e-0629627987307
Pubmed

Comparative analysis of the human dystrophin and utrophin gene structures.

DMD UTRN

7.54e-06296211861579
Pubmed

Distinct mechanical properties in homologous spectrin-like repeats of utrophin.

DMD UTRN

7.54e-06296230914715
Pubmed

Comparison of skeletal muscle pathology and motor function of dystrophin and utrophin deficient mouse strains.

DMD UTRN

7.54e-06296222284942
Pubmed

Ectoderm-mesenchyme and mesenchyme-mesenchyme interactions regulate Msx-1 expression and cellular differentiation in the murine limb bud.

MSX1 MSX2

7.54e-0629627537232
Pubmed

Haploinsufficiency of utrophin gene worsens skeletal muscle inflammation and fibrosis in mdx mice.

DMD UTRN

7.54e-06296217889902
Pubmed

Matricellular Protein CCN5 Gene Transfer Ameliorates Cardiac and Skeletal Dysfunction in mdx/utrn (±) Haploinsufficient Mice by Reducing Fibrosis and Upregulating Utrophin Expression.

DMD UTRN

7.54e-06296235557546
Pubmed

Comparison of MSX-1 and MSX-2 suggests a molecular basis for functional redundancy.

MSX1 MSX2

7.54e-0629628861098
Pubmed

Regulated expression of homeobox genes Msx-1 and Msx-2 in mouse mammary gland development suggests a role in hormone action and epithelial-stromal interactions.

MSX1 MSX2

7.54e-0629628660900
Pubmed

Characterization of the Ang/Tie2 Signaling Pathway in the Diaphragm Muscle of DMD Mice.

DMD UTRN

7.54e-06296237626761
Pubmed

Molecular heterogeneity of the dystrophin-associated protein complex in the mouse kidney nephron: differential alterations in the absence of utrophin and dystrophin.

DMD UTRN

7.54e-06296215565469
Pubmed

The N- and C-Terminal Domains Differentially Contribute to the Structure and Function of Dystrophin and Utrophin Tandem Calponin-Homology Domains.

DMD UTRN

7.54e-06296226516677
Pubmed

Assessment of cardiac function in three mouse dystrophinopathies by magnetic resonance imaging.

DMD UTRN

7.54e-06296222209498
Pubmed

A Protocol for Simultaneous In Vivo Imaging of Cardiac and Neuroinflammation in Dystrophin-Deficient MDX Mice Using [18F]FEPPA PET.

DMD UTRN

7.54e-06296237108685
Pubmed

Prevention of the dystrophic phenotype in dystrophin/utrophin-deficient muscle following adenovirus-mediated transfer of a utrophin minigene.

DMD UTRN

7.54e-06296210694796
Pubmed

Epithelial-mesenchymal interactions are required for msx 1 and msx 2 gene expression in the developing murine molar tooth.

MSX1 MSX2

7.54e-0629628101167
Pubmed

Enhanced currents through L-type calcium channels in cardiomyocytes disturb the electrophysiology of the dystrophic heart.

DMD UTRN

7.54e-06296224337461
Pubmed

Activation of calcineurin and stress activated protein kinase/p38-mitogen activated protein kinase in hearts of utrophin-dystrophin knockout mice.

DMD UTRN

7.54e-06296211297940
Pubmed

Rescue of severely affected dystrophin/utrophin-deficient mice through scAAV-U7snRNA-mediated exon skipping.

DMD UTRN

7.54e-06296222388933
Pubmed

Msx homeobox gene family and craniofacial development.

MSX1 MSX2

7.54e-06296214728799
Pubmed

Functional correction in mouse models of muscular dystrophy using exon-skipping tricyclo-DNA oligomers.

DMD UTRN

7.54e-06296225642938
Pubmed

Satellite cells and utrophin are not directly correlated with the degree of skeletal muscle damage in mdx mice.

DMD UTRN

7.54e-06296215703201
Pubmed

Utrophin suppresses low frequency oscillations and coupled gating of mechanosensitive ion channels in dystrophic skeletal muscle.

DMD UTRN

7.54e-06296225941878
Pubmed

Duchenne muscular dystrophy and the neuromuscular junction: the utrophin link.

DMD UTRN

7.54e-0629629297964
Pubmed

SERCA1 overexpression minimizes skeletal muscle damage in dystrophic mouse models.

DMD UTRN

7.54e-06296225652448
Pubmed

Utrophin Compensates dystrophin Loss during Mouse Spermatogenesis.

DMD UTRN

7.54e-06296228785010
Pubmed

Restoration of all dystrophin protein interactions by functional domains in trans does not rescue dystrophy.

DMD UTRN

7.54e-06296216307000
Pubmed

Expression of the dystrophin isoform Dp116 preserves functional muscle mass and extends lifespan without preventing dystrophy in severely dystrophic mice.

DMD UTRN

7.54e-06296221949353
Pubmed

Dystrophin and utrophin "double knockout" dystrophic mice exhibit a spectrum of degenerative musculoskeletal abnormalities.

DMD UTRN

7.54e-06296223097179
Pubmed

The role of utrophin and Dp71 for assembly of different dystrophin-associated protein complexes (DPCs) in the choroid plexus and microvasculature of the brain.

DMD UTRN

7.54e-06296215501597
Pubmed

Enhanced expression of the alpha 7 beta 1 integrin reduces muscular dystrophy and restores viability in dystrophic mice.

DMD UTRN

7.54e-06296211257121
Pubmed

Msh homeobox 1 (Msx1)- and Msx2-overexpressing bone marrow-derived mesenchymal stem cells resemble blastema cells and enhance regeneration in mice.

MSX1 MSX2

7.54e-06296228461333
Pubmed

Systemic human minidystrophin gene transfer improves functions and life span of dystrophin and dystrophin/utrophin-deficient mice.

DMD UTRN

7.54e-06296218973234
Pubmed

Renin-angiotensin-aldosterone system inhibitors improve membrane stability and change gene-expression profiles in dystrophic skeletal muscles.

DMD UTRN

7.54e-06296227881412
Pubmed

[Induction phenomena during vertebrate limb development and homeo box gene expression].

MSX1 MSX2

7.54e-0629628099267
Pubmed

Cytoskeletal interactions at the nuclear envelope mediated by nesprins.

SYNE3 SYNE1

7.54e-06296222518138
Pubmed

Dystrophins, utrophins, and associated scaffolding complexes: role in mammalian brain and implications for therapeutic strategies.

DMD UTRN

7.54e-06296220625423
Pubmed

Utrophin influences mitochondrial pathology and oxidative stress in dystrophic muscle.

DMD UTRN

7.54e-06296229065908
Pubmed

Stabilization of the cardiac sarcolemma by sarcospan rescues DMD-associated cardiomyopathy.

DMD UTRN

7.54e-06296231039133
Pubmed

Developmentally regulated expression and localization of dystrophin and utrophin in the human fetal brain.

DMD UTRN

7.54e-06296211796130
Pubmed

Dystrophin and dystrophin-related protein in the brains of normal and mdx mice.

DMD UTRN

7.54e-0629628159184
Pubmed

Dystrophin and utrophin: genetic analyses of their role in skeletal muscle.

DMD UTRN

7.54e-06296210679963
Pubmed

TAT-μUtrophin mitigates the pathophysiology of dystrophin and utrophin double-knockout mice.

DMD UTRN

7.54e-06296221565990
Pubmed

Fly DPP10 acts as a channel ancillary subunit and possesses peptidase activity.

DPP4 DPP10

7.54e-06296227198182
Pubmed

Generation and characterization of transgenic mice with the full-length human DMD gene.

DMD UTRN

7.54e-06296218083704
Pubmed

Generation of an Msx2-GFP conditional null allele.

MSX1 MSX2

7.54e-06296218442049
Pubmed

Dystrophin and dystrophin-related protein (utrophin) distribution in normal and dystrophin-deficient skeletal muscles.

DMD UTRN

7.54e-0629628186702
Pubmed

Contemporary cardiac issues in Duchenne muscular dystrophy. Working Group of the National Heart, Lung, and Blood Institute in collaboration with Parent Project Muscular Dystrophy.

DMD UTRN

7.54e-06296225940966
InteractionDISC1 interactions

SPTBN4 CCDC13 DST AKAP9 SYNE1 OSBPL8 MACF1 PLCG1 DMD UTRN IKBIP CCDC136 DYNC1H1

1.25e-074299613int:DISC1
InteractionDLX5 interactions

MSX1 MSX2 DLX2 HOXB13

1.05e-0529964int:DLX5
InteractionDRP2 interactions

DRP2 DMD UTRN

1.68e-0511963int:DRP2
InteractionPCNT interactions

SYNE3 DST AKAP9 ODAD1 SYNE1 MACF1 UTRN IKBIP

2.00e-05241968int:PCNT
GeneFamilyNKL subclass homeoboxes and pseudogenes

MSX1 MSX2 BARHL1 HMX3 NKX1-1 VAX2 DLX2 HMX1 EMX1 NKX1-2

2.19e-13677710519
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

SPTBN4 OSBPL8 PHLPP1 PLCG1 PLEK ARHGEF2 MCF2L

2.76e-05206777682
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

DRP2 DMD UTRN

5.79e-051877391
GeneFamilySpectrin repeat containing nuclear envelope family

SYNE3 SYNE1

1.07e-0447721252
GeneFamilyCD molecules|DASH family

DPP4 DPP10

3.71e-0477721205
GeneFamilyEF-hand domain containing|Plakins

DST MACF1

4.93e-048772939
GeneFamilyMyosin heavy chains

MYH6 MYH16

1.81e-03157721098
GeneFamilyDyneins, axonemal

DNAH2 DNAH5

2.34e-0317772536
GeneFamilyProtein phosphatases, Mg2+/Mn2+ dependent

PPM1F PHLPP1

2.34e-0317772701
GeneFamilyTransient receptor potential cation channels

TRPM5 TRPM1

6.30e-0328772249
CoexpressionGSE2128_C57BL6_VS_NOD_CD4CD8_DP_THYMOCYTE_DN

DPP4 RASGRP1 IFT140 METTL3 PLCG1 IKBIP NARS2

9.10e-06200967M6184
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#4_top-relative-expression-ranked_500

MSX1 MSX2 SOSTDC1 DLX2 TRPM1 ABCG5 NKX1-2

4.13e-0875947gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_500_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#3_top-relative-expression-ranked_1000

MSX1 MSX2 SOSTDC1 DLX2 TRPM1 ABCG5 NKX1-2

2.65e-0798947gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#5_top-relative-expression-ranked_200

MSX1 MSX2 SOSTDC1 DLX2 ABCG5 NKX1-2

4.29e-0765946gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_200_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_200

MSX1 MSX2 DST SOSTDC1 DLX2 TRPM1 ABCG5 NKX1-2

4.85e-07157948gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#3_top-relative-expression-ranked_200

MSX1 MSX2 DLX2 TRPM1 NKX1-2

5.95e-0737945gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_200_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#2_top-relative-expression-ranked_500

MSX1 MSX2 SOSTDC1 DLX2 TRPM1 NKX1-2

7.91e-0772946gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500_k2
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#3_top-relative-expression-ranked_1000

MSX1 MSX2 SOSTDC1 DLX2 TRPM1 ABCG5 NKX1-2

9.39e-07118947gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_1000

MSX1 MSX2 DST NALCN HECW2 OSBPL8 SOSTDC1 FNIP1 DLX2 TRPM1 PAX7 CDH2 ABCG5 NKX1-2

1.80e-058369414gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000
CoexpressionAtlasEctoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05

MSX1 MSX2 IFT140 EXD3 AKAP9 BARHL1 PPM1F SNX25 ST8SIA2 TRIM16L DMD ARHGEF2 MCF2L YJEFN3 CDH2 CCDC136 ANO8 DOP1A TECPR1

1.92e-0514669419PCBC_ratio_ECTO_vs_SC_cfr-2X-p05
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_100

MSX1 MSX2 DST DLX2 NKX1-2

2.50e-0578945gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#5_top-relative-expression-ranked_500

MSX1 MSX2 SOSTDC1 DLX2 TRPM1 ABCG5 NKX1-2

5.09e-05217947gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_500_k5
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500

NRXN3 RNF168 AKAP9 CMTM4 PHLPP1 DLX2 TRPM1 DMD CDH2 WWC1

6.57e-054939410Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000

NRXN3 TRPM5 RNF168 AKAP9 CMTM4 ST8SIA2 PHLPP1 SOSTDC1 DLX2 TRPM1 DMD CDH2 WWC1 DOP1A

1.04e-049839414Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_200

MSX1 MSX2 DST DLX2 TRPM1 NKX1-2

1.06e-04169946gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_200
CoexpressionAtlaskidney_adult_RenalCapsule_k-means-cluster#4_top-relative-expression-ranked_100

DPP4 ABCA9

1.16e-044942gudmap_kidney_adult_RenalCapsule_k4_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_500

MSX1 MSX2 DST HECW2 SOSTDC1 DLX2 TRPM1 ABCG5 NKX1-2

1.18e-04428949gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_500

MSX1 MSX2 DST HECW2 SOSTDC1 DLX2 TRPM1 CDH2 NKX1-2

1.20e-04429949gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#4_top-relative-expression-ranked_100

MSX2 DLX2 TRPM1

1.22e-0422943gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_100_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#3_top-relative-expression-ranked_100

MSX1 MSX2 NKX1-2

2.28e-0427943gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_100_k3
CoexpressionAtlasEctoderm Differentiated Cells_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05

MSX1 MSX2 IFT140 EXD3 BARHL1 SNX25 ST8SIA2 TRIM16L DMD MCF2L YJEFN3 CCDC136 ANO8 TECPR1

2.64e-0410759414PCBC_ratio_ECTO_vs_DE_cfr-2X-p05
CoexpressionAtlasEctoderm Differentiated Cells_vs_Mesoderm Day 5-Confounder_removed-fold2.0_adjp0.05

MSX1 MSX2 IFT140 EXD3 BARHL1 ST8SIA2 PHLPP1 TRIM16L DMD MCF2L YJEFN3 CCDC136 TECPR1

3.29e-049679413PCBC_ratio_ECTO_vs_MESO-5_cfr-2X-p05
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_500

MSX1 MSX2 DST SOSTDC1 DLX2 TRPM1 ABCG5 NKX1-2

3.39e-04390948gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_500
CoexpressionAtlasCD positive, CD4 Control, 4+ 8- B220-, Spleen, avg-4

RASGRP1 MACF1 PLCG1 GALNT6 UTRN TECPR1

3.44e-04210946GSM403995_500
CoexpressionAtlasalpha beta T cells, T.8Nve.PP, TCRb+ CD8+ CD44low CD62Lhigh, Peyer's Patch, avg-1

BARHL1 HMX3 MACF1 MYO18B UTRN TECPR1 NKX1-2

3.54e-04297947GSM538414_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_1000

TBC1D16 MSX1 MSX2 DST HECW2 SOSTDC1 DLX2 TRPM1 CDH2 ABCG5 IKBIP NKX1-2

3.67e-048509412gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_1000

SPTBN4 MSX1 TRPM5 AKAP9 CMTM4 DNAH2 ST8SIA2 SOSTDC1 MACF1 DLX2 TRPM1 DMD MCF2L

3.67e-049789413Facebase_RNAseq_e10.5_Mandibular Arch_1000
CoexpressionAtlasalpha beta T cells, T.4+8int.Th, 4+ 8int TCRhi, Thymus, avg-3

RASGRP1 OSBPL8 PLCG1 GALNT6 UTRN RGS3 TECPR1

3.91e-04302947GSM399362_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000

SPTBN4 MSX1 MSX2 RNF168 AKAP9 CMTM4 SYNE1 MACF1 VAX2 DLX2 TRPM1 ARHGEF2 PCSK4

4.08e-049899413Facebase_RNAseq_e10.5_Maxillary Arch_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#4

SPTBN4 MSX1 SYNE1 DNAH2 MACF1 TRPM1 PAX7 PCSK4 IKBIP DOP1A TECPR1

4.45e-047449411Facebase_RNAseq_e10.5_Medial Nasal Eminence_2500_K4
CoexpressionAtlasCD positive, CD4 Control, 4+8-B220-, Spleen, avg-2

RASGRP1 MACF1 PLCG1 GALNT6 UTRN TECPR1

4.85e-04224946GSM403994_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_100

MSX2 DST DLX2 TRPM1

5.54e-0485944DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_100
CoexpressionAtlasalpha beta T cells, T.4Nve.PP, TCR+ CD4+ CD44low CD62Lhigh, Peyer's Patch, avg-2

RASGRP1 MACF1 PLCG1 GALNT6 UTRN DOP1A TECPR1

6.27e-04327947GSM538380_500
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T|COVID-19_Severe / Disease, condition lineage and cell class

RASGRP1 FCGBP SYNE1 MACF1 PLEK CCDC65 UTRN

2.45e-07200957f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

DST NALCN CMTM4 SYNE1 PHLPP1 DYNC1H1

2.21e-06177956e8ab340b20cd41554c3841fe980e078e878af35f
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST AKAP9 FNIP1 MACF1 CDH2 DYNC1H1

3.87e-061959563e519cffa6144a62b06124642a14c9ff39b76554
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ODAD1 SYNE1 CRACDL DNAH2 CCDC65 DNAH5

3.87e-061959563486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST AKAP9 FNIP1 MACF1 CDH2 DYNC1H1

3.87e-061959567796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellCOVID-19_Severe-Lymphoid_T/NK-gd_T|COVID-19_Severe / Disease group, lineage and cell class

RASGRP1 SYNE1 MACF1 PLEK CCDC65 UTRN

3.87e-061959569990440bda7fac5d00ef80444fab07459be625e1
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AKAP9 ODAD1 SYNE1 DNAH2 CCDC65 DNAH5

4.11e-0619795691637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AKAP9 ODAD1 SYNE1 DNAH2 CCDC65 DNAH5

4.11e-0619795622c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AKAP9 ODAD1 SYNE1 DNAH2 DMD DNAH5

4.11e-0619795674a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AKAP9 ODAD1 SYNE1 DNAH2 CCDC65 DNAH5

4.11e-061979563bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AKAP9 ODAD1 SYNE1 DNAH2 CCDC65 DNAH5

4.11e-0619795687db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCellhealthy_donor-Lymphocytic-ILC-NK_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

SYNE1 MACF1 PLEK ITGAM UTRN RGS3

4.23e-06198956d7053a898e04478c577381085f615edaad3cdc5b
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ODAD1 SYNE1 CRACDL DNAH2 CCDC65 DNAH5

4.23e-06198956ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellhealthy_donor-Lymphocytic-ILC|healthy_donor / Disease condition, Lineage, Cell class and subclass

SYNE1 MACF1 PLEK ITGAM UTRN RGS3

4.23e-06198956aa33be29e26f1b8facfc894413099083ae3bbb1b
ToppCellControl-NK|Control / Disease condition and Cell class

SYNE1 MACF1 PLEK ITGAM UTRN RGS3

4.35e-06199956f3316fb97c6065286ffd22a0ad9fe7aa5b3b5650
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRXN3 DST VAX2 DLX2 DMD CDH2

4.35e-06199956a816b0eed80530113b7e720bbd2311a544ed8ed1
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

SYNE1 MACF1 PLCG1 PLEK UTRN RGS3

4.48e-062009562281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Cilia-bearing_cell|6m / Sample Type, Dataset, Time_group, and Cell type.

MSX1 CCDC13 ODAD1 SOSTDC1 CCDC65 DNAH5

4.48e-06200956177f9ad8dd8635394c575a2b30140184df0bd51e
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast-mesenchymal_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SPTBN4 CMTM4 TRPM1 DMD ABCG5

6.18e-06121955176de42c088988fe1a7838f96add26ee8a30e543
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Nonmucinous_Lepidic_Adenocarcinoma-7|TCGA-Lung / Sample_Type by Project: Shred V9

C9orf152 CCDC13 IFT140 SNX25 DNAH2

8.77e-0613095517a4ee699adfa265335b1abfe6cb0f3f7c93362b
ToppCell3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

AKAP9 SYNE1 MACF1 PLCG1 UTRN

1.05e-05135955ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SYNE3 GALNT6 PLEK ITGAM MARCO

2.32e-051599550c2437da5443fc3aff66f8ef311f02aa434a1fb0
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCDC13 DRP2 SOSTDC1 CDH2 HOXB13

2.69e-051649553caf4cdaa0164907893fea61e251fd8b5fa926e4
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MORC1 SYNE3 SH2D3C UTRN RGS3

2.77e-05165955a74751e0ec857aa974bec04ccc747c004a8f6e01
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRXN3 DST PHLPP1 DMD CDH2

3.11e-051699552456b3e7776e8a2214972be1b4d66a3ca5480ae0
ToppCellE18.5-Immune-Immune_Myeloid-Granulocytic-Basophil|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPTBN4 SYNE3 SYNE1 GALNT6 ITGAM

3.11e-05169955b23d0aaa2da333b9c69a7aee862d5a5d2a1bf79b
ToppCellE18.5-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPTBN4 SYNE3 SYNE1 GALNT6 ITGAM

3.11e-0516995583d1bcf33872b01ea9614f608a3e4ab30df25c7e
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC13 ODAD1 DNAH2 DNAH5 PCSK4

3.11e-0516995514aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

FCGBP MYO18B ITGAM CDH2 MARCO

3.20e-051709554232fe937909f93d3736988c707b8f95ce993398
ToppCelldroplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_ductal_cel|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP DRP2 ODAD1 ST8SIA2 ITIH2

3.38e-05172955c0bda7153e02bee7d0326138cc684151c404c2a1
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCGBP SYNE1 PLEK PCSK4 ITIH2

3.38e-05172955e3a8891694343b6b01e80a200ae338d24797e417
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SYNE3 GALNT6 PLEK ITGAM MARCO

3.47e-0517395520f7dfe7d92a3dbec9da9a1f3185aa10cb8f0a3c
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FCGBP BARHL1 CCDC65 DNAH5 ITIH2

3.47e-05173955a809be2630d2b91b53b82b5e2bb99e05524597c1
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 MACF1 ZNF561 DMD ABCA9

3.77e-05176955749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

NALCN HECW2 SYNE1 ITGAM CDH2

4.09e-05179955cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE3 HECW2 SH2D3C UTRN CCDC136

4.42e-0518295541b070085edba7a58b81c20aa4942d06f745acf8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE3 HECW2 SH2D3C UTRN CCDC136

4.42e-051829555e9a67b2de0daa4fdc344b10a857d8a901ad810e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE3 HECW2 SH2D3C UTRN CCDC136

4.42e-05182955b0fe042c71d6ab8c75abd7ba9d2de00b72d01c0c
ToppCellCOVID-19_Mild-gd_T|COVID-19_Mild / Disease condition and Cell class

SYNE1 MACF1 PLEK ITGAM UTRN

4.54e-05183955f593a89b0aa8fffdfa403769916facfd30358521
ToppCellMild/Remission-B_intermediate-10|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SPTBN4 RASGRP1 MACF1 EEA1 PLEK

4.54e-05183955278064c9f0582463b83bf156d34e77f60187613b
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

NALCN OSBPL8 EEA1 UTRN ABCA9

4.66e-0518495567164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRXN3 DST DLX2 DMD CDH2

4.66e-05184955226ccac00ac1c3a0ad7283785fd14312320e0ca6
ToppCellCOVID-19-Heart-CM_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYH6 NALCN DMD MYO18B CDH2

4.66e-05184955e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCellTCGA-Breast-Metastatic-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-1|TCGA-Breast / Sample_Type by Project: Shred V9

CCDC13 HMX3 PDILT EMX1

4.72e-0593954504e11d516073492d6ef8cd3bd3b8a652351f2b2
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ODAD1 CRACDL DNAH2 CCDC65 DNAH5

4.91e-0518695576033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCDC13 DRP2 BARHL1 HECW2 HMX3

4.91e-05186955bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

MYH6 DMD MYO18B CDH2 RGS3

5.16e-051889556d249fe92d51a19da19ec14bb2262d394255d577
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRXN3 DST DLX2 DMD CDH2

5.16e-05188955ccd2541892112a7a303f766adf9a7afeb754498c
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NALCN PPM1F HECW2 SH2D3C MCF2L

5.29e-051899550d18ea72bd58d32a8ab9a61cf97f5786642f804b
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IFT140 HECW2 SYNE1 SH2D3C SOSTDC1

5.29e-05189955b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NRXN3 NALCN PPM1F HECW2 SH2D3C

5.29e-0518995555a1776a4ce049959b3f13a43744c7314bc1f00a
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

MYH6 DST DMD MYO18B CDH2

5.43e-05190955fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

MYH6 DST DMD MYO18B CDH2

5.56e-0519195525f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

MYH6 DMD MYO18B CDH2 RGS3

5.56e-051919555d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCellRA-09._Endothelium_I|RA / Chamber and Cluster_Paper

SYNE1 CRACDL SH2D3C MCF2L UTRN

5.70e-051929558a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ODAD1 CRACDL DNAH2 PAX7 DNAH5

5.84e-05193955ea345d34440b25f65358a53dc72831998d1c3620
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

AKAP9 SYNE1 MACF1 PLCG1 UTRN

5.84e-051939559337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellCOPD-Lymphoid-NK|Lymphoid / Disease state, Lineage and Cell class

SYNE1 PLEK ITGAM UTRN RGS3

5.84e-051939550020249fa71afb500af73700543bb6f349be6b10
ToppCellRV-09._Endothelium_I|RV / Chamber and Cluster_Paper

SYNE1 CRACDL SH2D3C MCF2L UTRN

5.99e-051949557b408096e717f2327c12aea35a8d5fc4621d3b06
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SYNE1 PLEK ITGAM CCDC65 RGS3

5.99e-05194955a8dc3336aa4ef497f6d26cede02ddac425e7c655
ToppCellRA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

MYH6 DMD MYO18B CDH2 RGS3

5.99e-0519495589812fb164065041357bb37a3c2d87028ec3de4e
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

MYH6 DMD MYO18B CDH2 RGS3

5.99e-05194955c3535f7cc0076653c72db582047cff053c322397
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

MYH6 DST DMD MYO18B CDH2

6.14e-0519595575fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellLV-09._Endothelium_I|World / Chamber and Cluster_Paper

SYNE1 CRACDL SH2D3C MCF2L UTRN

6.14e-0519595519e0a6c3eae1615aaa39767300acd937dfcb2a7f
ToppCellCOVID-19-Heart-EC_1|Heart / Disease (COVID-19 only), tissue and cell type

HECW2 SYNE1 SH2D3C MCF2L UTRN

6.14e-0519595550a193475db1bb1e05b8590225a553688c372c14
ToppCellfacs-Lung-nan-3m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPM1F HECW2 SH2D3C PLCG1 UTRN

6.14e-051959557f9b7f15006610ad591063d90e90367bd6083c7f
ToppCellfacs-Heart-RA-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPM1F SH2D3C MCF2L UTRN RGS3

6.14e-0519595530c75761079fa1e1a3b84d23c88a222f459d5ce5
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ODAD1 CRACDL DNAH2 CCDC65 DNAH5

6.29e-0519695527b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

RASGRP1 SYNE1 MACF1 CCDC65 UTRN

6.29e-05196955418e8e0a51c5cb60e3b903e7d2d800dc8b9f3d5c
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RASGRP1 SYNE1 MACF1 CCDC65 UTRN

6.29e-051969556beaf0c2799424c59819b286fbb5c1a83d85e4d1
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ODAD1 SYNE1 DNAH2 CCDC65 DNAH5

6.29e-05196955d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRXN3 DST DLX2 DMD CDH2

6.44e-05197955bb35a2b7320fda92e9cd42f536b7bd54e3a73a32
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRXN3 DST DLX2 DMD CDH2

6.44e-051979551018aac22659c081d227d566afa29b1748c18ade
ToppCellCOVID_vent-Lymphocytic-T_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

DPP4 RASGRP1 SYNE1 MACF1 PLCG1

6.44e-05197955ad702e440a74d54cfdcb8bb1c66bd8e0e71ab04e
ToppCellT_cells-CTLs|World / Immune cells in Kidney/Urine in Lupus Nephritis

RASGRP1 SYNE1 MACF1 PLEK CCDC65

6.44e-051979552de34e20915a247bee75aa40495e23c20bb23e18
ToppCellCOVID_vent-Lymphocytic-T_cell-CD8+_Memory_T_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

RASGRP1 SYNE1 MACF1 PLEK UTRN

6.44e-05197955d4dfb3b561d0783cdbee4e8d27009ad81df695cb
ToppCellControl-Control-Lymphocyte-T/NK-NK_activated|Control / Disease, condition lineage and cell class

SYNE1 MACF1 PLCG1 PLEK UTRN

6.60e-0519895576d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPM1F HECW2 SYNE1 SH2D3C UTRN

6.60e-0519895531ba87552be97c9b78c9e82f98e96699ccb19824
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPM1F HECW2 SYNE1 SH2D3C UTRN

6.60e-05198955451003a21162eeae90739fdb502bb50b362d80c8
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE1 MACF1 PLEK UTRN RGS3

6.60e-051989550e918e9db9b884f5328d438e90efe065e27266ee
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRXN3 DST DLX2 DMD CDH2

6.60e-0519895550dfe6efca76ea9683a19b6bff59cb5030d346f1
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRXN3 DST DLX2 DMD CDH2

6.60e-051989555b9a7b9f53a3d9cf8d6e6a7c1c94514b22cf9fa8
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE1 MACF1 PLEK UTRN RGS3

6.60e-05198955ce92d5fbc2eac27fb246b044fb1914ab92506275
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SYNE1 MACF1 PLEK UTRN RGS3

6.60e-05198955fed823d6e684d113bcc9ff3cd1803bb001aa02fa
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPM1F HECW2 SYNE1 SH2D3C UTRN

6.60e-05198955440af8f90c7afa1c07000806bcf9110b70f489fb
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SYNE1 MACF1 PLEK UTRN RGS3

6.60e-051989551ef3a6bd681c223eed58300348adfef89df5563c
ToppCellmetastatic_Brain-Endothelial_cells-Tumor_ECs|metastatic_Brain / Location, Cell class and cell subclass

MSX1 BARHL1 HECW2 SH2D3C MCF2L

6.60e-051989555e274f29cc796dae7d64d6035e904816c25f9914
ToppCellCOVID-19_Moderate-NK|COVID-19_Moderate / disease group, cell group and cell class

SYNE1 PLEK ITGAM UTRN RGS3

6.75e-05199955e0e83ba511957be9ad3413460dcb6b7d7b65dd18
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE1 MACF1 PLEK UTRN RGS3

6.75e-051999554820f5bcd7bc34c2ebf6a3422cc8eb383a3b5a4e
ToppCell(07)_Ionocytes|World / shred by cell type by condition

DPP4 C9orf152 SOSTDC1 DLX2 MCF2L

6.75e-051999558194777d367405a7840787e977854b5c07e3bd6b
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRXN3 DST DLX2 DMD CDH2

6.75e-05199955a76aa30fb264bdcbc0cb09113f814fc5a89e7319
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRXN3 DST DLX2 DMD CDH2

6.75e-051999555f350d9c7da9ac111bf22623dd4fed7f7983c9fc
ToppCellmild-MAIT|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DPP4 RASGRP1 SYNE1 MACF1 UTRN

6.75e-05199955cbe1fb6d2c5fca7a1baf1ad20afcdf8e8e11bd84
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE1 MACF1 PLEK UTRN RGS3

6.75e-05199955eb05ccae5187e4701bbbe6d714a6d2808fbcf306
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SYNE1 MACF1 PLEK UTRN RGS3

6.75e-0519995510c8729b779073c3bf808e85958d59147f0be5c5
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

DST AKAP9 OSBPL8 EEA1 UTRN

6.75e-05199955c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE1 MACF1 PLEK UTRN RGS3

6.75e-05199955867fd292f3879982422e840e087bfdb3b21a8715
ToppCellControl-Lymphoid_T/NK-NK|Control / Disease group, lineage and cell class

SYNE1 MACF1 PLEK UTRN RGS3

6.75e-0519995594b2693a8378b9b2c58c6aebb2c6658d75b2e3de
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors|1_mon / Sample Type, Dataset, Time_group, and Cell type.

RASGRP1 PHLPP1 DHX33 DMD UTRN

6.75e-05199955358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRXN3 DST DLX2 DMD CDH2

6.75e-051999551761669ec514fdb4175042f11b9a31fa5687fc2b
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

RASGRP1 AKAP9 SYNE1 MACF1 UTRN DYNC1H1

8.93e-0849506GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

DST SYNE1 MACF1 DYNC1H1

8.15e-0550504GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_4
Drugplakin

SPTBN4 SYNE3 DST SYNE1 MACF1 DMD UTRN DYNC1H1

2.05e-0982968CID000018752
DiseaseMalformations of Cortical Development, Group II

CDH2 DYNC1H1

1.05e-052962C1837249
DiseasePrimary ciliary dyskinesia

ODAD1 CCDC65 DNAH5

2.20e-0436963cv:C0008780
DiseaseDuchenne muscular dystrophy (implicated_via_orthology)

DRP2 DMD UTRN

2.20e-0436963DOID:11723 (implicated_via_orthology)
DiseasePrimary Ciliary Dyskinesia

ODAD1 CCDC65 DNAH5

4.88e-0447963C4551720
Diseaseperiodontitis

CCDC13 HMX3 DMD CDH2 HSP90AA4P

8.25e-04223965EFO_0000649
DiseaseLibman-Sacks Disease

RASGRP1 PHRF1 ITGAM

9.04e-0458963C0242380
Diseaseproliferative diabetic retinopathy

NRXN3 DPP10 UTRN

1.05e-0361963EFO_0009322
Diseaseamyotrophic lateral sclerosis, age at onset

NRXN3 ARHGEF2

1.07e-0315962EFO_0004847, MONDO_0004976
Diseasesphingosine 1-phosphate measurement

DMD MARCO

1.55e-0318962EFO_0800185
DiseaseLupus Erythematosus, Systemic

RASGRP1 PHRF1 ITGAM

1.63e-0371963C0024141
DiseaseCraniofacial Abnormalities

MSX1 MSX2 DLX2 HMX1

1.71e-03156964C0376634
Diseasediet measurement, colorectal cancer

MORC1 ST8SIA2

1.73e-0319962EFO_0008111, MONDO_0005575
Diseasemuscular dystrophy (implicated_via_orthology)

DMD UTRN

2.11e-0321962DOID:9884 (implicated_via_orthology)
Diseasediet measurement

NRXN3 DST RNF168 NALCN NRF1 HECW2 DEPDC5 EEA1 DNAH5 RGS3

2.20e-0310499610EFO_0008111
Diseasemedial orbital frontal cortex volume measurement

NRXN3 HSP90AA4P

2.99e-0325962EFO_0010315
Diseasedescending aortic diameter

TBC1D16 SPTBN4 MYH6

3.00e-0388963EFO_0021788
Diseasesystemic scleroderma, systemic lupus erythematosus

PHRF1 ITGAM

3.24e-0326962EFO_0000717, MONDO_0007915

Protein segments in the cluster

PeptideGeneStartEntry
WRVISSIEQKTERNE

YWHAB

61

P31946
SLTSDRTRNWVLQQK

AKAP9

3471

Q99996
RTRNWVLQQKIEGET

AKAP9

3476

Q99996
ETRKTISGVALWRQQ

ABCA9

831

Q8IUA7
RDDRSTWIRVIQQSV

ARHGEF2

556

Q92974
INTQWRTVLREVKTR

CCDC65

61

Q8IXS2
TTQINARDWSRKLTQ

RASGRP1

171

O95267
NLTDTQVKTWYQNRR

BARHL1

216

Q9BZE3
AFVWNERRQNKTTTR

DOP1A

1831

Q5JWR5
SEKILLSWVRQSTRN

DMD

136

P11532
LTQTQVKIWFQNRRS

DLX2

191

Q07687
KTVVRWLNRAQNISI

DPP10

331

Q8N608
TSQERQSIIRFWLQN

ANO8

161

Q9HCE9
QRLRDQIKTWVASNE

CNOT3

56

O75175
VNAVWINKERRSSLS

C9orf152

76

Q5JTZ5
KRLLVTVWNRASQSR

RGS3

216

P49796
AQRTKLTEARVQVWF

PAX7

251

P23759
QRSQIANITTVWRAQ

MORC1

671

Q86VD1
AVQNVHSVWTLRRVK

ANAPC1

261

Q9H1A4
KWRIERGVVQQTESL

HECW2

1411

Q9P2P5
KVVVQNERREEWTSL

DEPDC5

256

O75140
AQRQIQEWGVSVRTL

ESPNL

641

Q6ZVH7
ELRIKNLTQSRSTTW

nan

236

O00370
RTWRNDLISATKTQV

ITIH2

356

P19823
TKTTQIEDPRVQWRR

WWC1

76

Q8IX03
NLLISVQSRWEKVVQ

DST

6676

Q03001
LTETQVKIWFQNRRN

HMX3

266

A6NHT5
IWNLVQKTTSSLDRR

ECE2

436

P0DPD6
WFQQQTLQRRVKRSV

PCSK4

101

Q6UW60
QLTETQVKIWFQNRR

HMX1

241

Q9NP08
AWHDVKVTRNLRQVT

NRXN3

341

Q9Y4C0
DVRTEEQKQRVSWTQ

NRF1

246

Q16656
EQKQRVSWTQALRTI

NRF1

251

Q16656
SRALVKRVTWNLQES

PHRF1

1396

Q9P1Y6
LLVSVQSRWEKVVQR

MACF1

2651

O94854
ATQERISLQWLRRIQ

DPP4

306

P27487
TVLNQTWVLKARVND

CYHR1

256

Q6ZMK1
QTRALDKQIQEWETR

ODAD1

76

Q96M63
WITVTRQKRRGTLDQ

CRACDL

826

Q6NV74
RLQEEINEVKTWSNR

IKBIP

121

Q70UQ0
VSVQSRWEKVVQRSI

MACF1

6526

Q9UPN3
RVDEIIWVKTNQLQR

METTL3

451

Q86U44
IWVKTNQLQRIIRTG

METTL3

456

Q86U44
LWQRVTRAINAKDQT

OSBPL8

686

Q9BZF1
EWQSSQRRVSELEKQ

EEA1

1256

Q15075
RVKQWITINEANVLS

GBA3

156

Q9H227
LRLEQRQWKVTVNGV

FCGBP

2521

Q9Y6R7
TLRLEQRQWKVTVNG

FCGBP

3721

Q9Y6R7
TSVIARNQVRLAEVW

GALNT6

421

Q8NCL4
KWTVQVASSQRRVTD

FNIP1

1056

Q8TF40
TWRGRAQQILVLQSK

CCDC13

261

Q8IYE1
VQRVSKTQAWQRTGR

DHX33

391

Q9H6R0
DITSCRQQWTRQILK

ABCG5

56

Q9H222
SRLQVLQAQLTWVRV

MARCO

111

Q9UEW3
SIWERQSNRTVRVTQ

MAN2B2

601

Q9Y2E5
WVNEIRKVLTSQLQA

MCF2L

936

O15068
QSGVNRWIREIQKVT

DYNC1H1

246

Q14204
LSETQVKVWFQNRRT

EMX1

231

Q04741
TKDQVANSTIVQRLW

HSP90AA4P

206

Q58FG1
SERQITIWFQNRRVK

HOXB13

256

Q92826
RNWEIIETTRSKIEQ

DNAH2

1281

Q9P225
RVQVRTWQGTVKQLL

IFT140

501

Q96RY7
VTIKRNWTITRLNGD

CDH2

646

P19022
QINVRWKQLQASVSE

DRP2

316

Q13474
RRQLWKHSVTRVLTQ

DNAH5

6

Q8TE73
SQRQWLVSIHAIRNT

PPM1F

151

P49593
LTETQVKIWFQNRRA

MSX2

181

P35548
SAALVVWLRRQISQK

PDILT

141

Q8N807
NSEKILLSWVRQTTR

UTRN

151

P46939
SWKYQVQTERQRIQT

TRIM34

171

Q9BYJ4
QRNLNVETTRISHWK

TRIM48

171

Q8IWZ4
TAQWRNLSVEVRSVR

SYNE1

591

Q8NF91
NQRWDNLQKRVTSIL

SYNE1

8086

Q8NF91
RQWIVVTTQKLEAHR

SYNE3

661

Q6ZMZ3
TETQVKIWFQNRRTK

NKX1-1

336

Q15270
SLTETQVKIWFQNRR

NKX1-2

201

Q9UD57
LTETQVKIWFQNRRA

MSX1

211

P28360
RTINKQIRDTVSWIF

SNX25

716

Q9H3E2
IQGWIRSVRSQKEVL

NARS2

46

Q96I59
VIDWLVSNQSVRNRQ

PLEK

161

P08567
WRHNQTLSLRIRKQI

ST8SIA2

86

Q92186
VSTLQNQRSQRSWRL

ITGAM

831

P11215
RVLSKANSEVAQWRT

MYH6

1361

P13533
RTQRATERWLQSQTL

CCDC136

261

Q96JN2
VNTFLAVQKWRVSVR

CMTM4

166

Q8IZR5
AVQKWRVSVRQQSTN

CMTM4

171

Q8IZR5
EWEIQPRTKRSSLQQ

ZNF561

81

Q8N587
IVRWTKLLQNITSHQ

TRPM5

296

Q9NZQ8
DTIQRSKWIRAVNRV

THAP9

31

Q9H5L6
AAWRKQIFQQLTERT

TECPR1

576

Q7Z6L1
WRNVQFTVDKDVVRT

TBC1D16

481

Q8TBP0
TTSLVQRRKQAWGRQ

YJEFN3

41

A6XGL0
FQVKLETRQITWSRG

PLCG1

51

P19174
NSRWNRIVELVEQRK

SPTBN4

966

Q9H254
TRRNSLVNVELWTII

RNF168

66

Q8IYW5
WRCVNDKTRTQRIQL

SOSTDC1

131

Q6X4U4
LREKVTQENTSVRWE

MYO18B

1626

Q8IUG5
QRLVSKLNTEVTTWR

MYH16

521

Q9H6N6
LTTEWQCQVQKITRS

TRPM1

1466

Q7Z4N2
LSETQVKVWFQNRRT

VAX2

141

Q9UIW0
RWLRQVSKVASQRIS

PHLPP1

626

O60346
QISRLEQTWVTLRQR

SH2D3C

696

Q8N5H7
RLQEENRKVTNTTPW

TRIM16L

171

Q309B1
RITNILKRSGEQIWS

NALCN

166

Q8IZF0
LQALQTLWSTRERKQ

EXD3

26

Q8N9H8