Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	benzodiazepine receptor binding	RIMBP3 RIMBP3C RIMBP3B	3.41e-06	5	141	3	GO:0030156
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	ERCC6 EP400 WRNIP1 INO80 TOP2A TOP2B	2.86e-04	127	141	6	GO:0008094
GeneOntologyMolecularFunction	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	TOP2A TOP2B	2.94e-04	4	141	2	GO:0003918
Domain	SPOC_C	RBM15 PHF3 RBM15B	7.94e-06	6	139	3	IPR012921
Domain	SPOC	RBM15 PHF3 RBM15B	7.94e-06	6	139	3	PF07744
Domain	-	TOP2A TOP2B	5.50e-05	2	139	2	3.40.50.670
Domain	DTHCT	TOP2A TOP2B	5.50e-05	2	139	2	IPR012542
Domain	DNA_gyraseB	TOP2A TOP2B	5.50e-05	2	139	2	PF00204
Domain	-	TOP2A TOP2B	5.50e-05	2	139	2	3.90.199.10
Domain	TopoIIA_CS	TOP2A TOP2B	5.50e-05	2	139	2	IPR018522
Domain	AMPKBI	PRKAB1 PRKAB2	5.50e-05	2	139	2	PF04739
Domain	AMPKBI	PRKAB1 PRKAB2	5.50e-05	2	139	2	SM01010
Domain	AMPK1_CBM	PRKAB1 PRKAB2	5.50e-05	2	139	2	PF16561
Domain	Topo_IIA	TOP2A TOP2B	5.50e-05	2	139	2	IPR001241
Domain	DNA_topoisoIV	TOP2A TOP2B	5.50e-05	2	139	2	PF00521
Domain	Topo_IIA_A/C_ab	TOP2A TOP2B	5.50e-05	2	139	2	IPR013758
Domain	Topo_IIA_A_a	TOP2A TOP2B	5.50e-05	2	139	2	IPR013757
Domain	Topo_IIA_cen_dom	TOP2A TOP2B	5.50e-05	2	139	2	IPR013759
Domain	TOP4c	TOP2A TOP2B	5.50e-05	2	139	2	SM00434
Domain	TOP2c	TOP2A TOP2B	5.50e-05	2	139	2	SM00433
Domain	Topo_IIA-like_dom	TOP2A TOP2B	5.50e-05	2	139	2	IPR013760
Domain	Topo_IIA_bsu_dom2	TOP2A TOP2B	5.50e-05	2	139	2	IPR013506
Domain	DTHCT	TOP2A TOP2B	5.50e-05	2	139	2	PF08070
Domain	-	TOP2A TOP2B	5.50e-05	2	139	2	1.10.268.10
Domain	AMPK1_CBM	PRKAB1 PRKAB2	5.50e-05	2	139	2	IPR032640
Domain	TOPRIM_C	TOP2A TOP2B	5.50e-05	2	139	2	IPR031660
Domain	TOPRIM_C	TOP2A TOP2B	5.50e-05	2	139	2	PF16898
Domain	ASC_dom	PRKAB1 PRKAB2	5.50e-05	2	139	2	IPR006828
Domain	Topo_IIA_A/C	TOP2A TOP2B	5.50e-05	2	139	2	IPR002205
Domain	TOPOISOMERASE_II	TOP2A TOP2B	5.50e-05	2	139	2	PS00177
Domain	Arg_repress_C-like	TOP2A TOP2B	1.64e-04	3	139	2	IPR024946
Domain	-	TOP2A TOP2B	1.64e-04	3	139	2	3.30.1360.40
Domain	SPOC_met	RBM15 RBM15B	1.64e-04	3	139	2	IPR010912
Domain	-	ROCK2 CDC42BPG EPS8L2 PSD PLEKHA6 EPB41L3 PLEKHG5 FRMD4A SBF1 TBC1D1 PLCB3	1.68e-04	391	139	11	2.30.29.30
Domain	Toprim	TOP2A TOP2B	3.27e-04	4	139	2	PF01751
Domain	SPOC	RBM15 RBM15B	3.27e-04	4	139	2	PS50917
Domain	Toprim_domain	TOP2A TOP2B	3.27e-04	4	139	2	IPR006171
Domain	TOPRIM	TOP2A TOP2B	3.27e-04	4	139	2	PS50880
Domain	PH_dom-like	ROCK2 CDC42BPG EPS8L2 PSD PLEKHA6 EPB41L3 PLEKHG5 FRMD4A SBF1 TBC1D1 PLCB3	3.49e-04	426	139	11	IPR011993
Domain	SH3_2	RIMBP3 SORBS3 RIMBP3C MYO15A RIMBP3B	4.56e-04	86	139	5	PF07653
Domain	SH3_2	RIMBP3 SORBS3 RIMBP3C MYO15A RIMBP3B	4.56e-04	86	139	5	IPR011511
Domain	-	RBM15 RBM15B	5.42e-04	5	139	2	2.40.290.10
Domain	SPIN/Ssty	SPIN1 SPIN3	5.42e-04	5	139	2	IPR003671
Domain	Spin-Ssty	SPIN1 SPIN3	5.42e-04	5	139	2	PF02513
Domain	SPOC-like_C_dom	RBM15 RBM15B	5.42e-04	5	139	2	IPR016194
Domain	SH3	EPS8L2 FNBP1L RIMBP3 SORBS3 RIMBP3C MYO15A RIMBP3B	1.18e-03	216	139	7	SM00326
Domain	SH3	EPS8L2 FNBP1L RIMBP3 SORBS3 RIMBP3C MYO15A RIMBP3B	1.18e-03	216	139	7	PS50002
Domain	SH3_domain	EPS8L2 FNBP1L RIMBP3 SORBS3 RIMBP3C MYO15A RIMBP3B	1.31e-03	220	139	7	IPR001452
Domain	Alkaline_phosphatase_core	ENPP3 ARSB SULF1	1.56e-03	31	139	3	IPR017850
Domain	Alkaline_Pase-like_a/b/a	ENPP3 ARSB SULF1	1.56e-03	31	139	3	IPR017849
Domain	-	ENPP3 ARSB SULF1	1.56e-03	31	139	3	3.40.720.10
Domain	SNF2_N	ERCC6 EP400 INO80	1.71e-03	32	139	3	IPR000330
Domain	SNF2_N	ERCC6 EP400 INO80	1.71e-03	32	139	3	PF00176
Domain	SH3_9	RIMBP3 SORBS3 RIMBP3C RIMBP3B	2.74e-03	78	139	4	PF14604
Domain	PDZ	DVL3 MAGI2 GRID2IP GRIP2 PDZD2	4.09e-03	141	139	5	PF00595
Domain	uDENN	DENND2B SBF1	4.72e-03	14	139	2	SM00800
Domain	FERM_M	EPB41L3 FRMD4A MYO15A	4.85e-03	46	139	3	PF00373
Domain	PDZ	DVL3 MAGI2 GRID2IP GRIP2 PDZD2	5.02e-03	148	139	5	SM00228
Domain	-	DVL3 MAGI2 GRID2IP GRIP2 PDZD2	5.31e-03	150	139	5	2.30.42.10
Domain	-	ARID5A JARID2	5.42e-03	15	139	2	1.10.150.60
Domain	BRIGHT	ARID5A JARID2	5.42e-03	15	139	2	SM00501
Domain	ARID_dom	ARID5A JARID2	5.42e-03	15	139	2	IPR001606
Domain	ARID	ARID5A JARID2	5.42e-03	15	139	2	PS51011
Domain	uDENN	DENND2B SBF1	5.42e-03	15	139	2	PF03456
Domain	FH2	GRID2IP FMN1	5.42e-03	15	139	2	PS51444
Domain	FH2_Formin	GRID2IP FMN1	5.42e-03	15	139	2	IPR015425
Domain	FH2	GRID2IP FMN1	5.42e-03	15	139	2	PF02181
Domain	-	PSD ARFGEF2	5.42e-03	15	139	2	1.10.1000.11
Domain	ARID	ARID5A JARID2	5.42e-03	15	139	2	PF01388
Domain	Sec7	PSD ARFGEF2	5.42e-03	15	139	2	PF01369
Domain	Sec7_alpha_orthog	PSD ARFGEF2	5.42e-03	15	139	2	IPR023394
Domain	FH2	GRID2IP FMN1	5.42e-03	15	139	2	SM00498
Domain	PDZ	DVL3 MAGI2 GRID2IP GRIP2 PDZD2	5.46e-03	151	139	5	PS50106
Domain	PDZ	DVL3 MAGI2 GRID2IP GRIP2 PDZD2	5.61e-03	152	139	5	IPR001478
Domain	-	ACBD5 EPB41L3 FRMD4A	5.79e-03	49	139	3	1.20.80.10
Domain	FERM_central	EPB41L3 FRMD4A MYO15A	5.79e-03	49	139	3	IPR019748
Domain	FERM_domain	EPB41L3 FRMD4A MYO15A	5.79e-03	49	139	3	IPR000299
Domain	FERM/acyl-CoA-bd_prot_3-hlx	ACBD5 EPB41L3 FRMD4A	6.12e-03	50	139	3	IPR014352
Domain	FERM_1	EPB41L3 FRMD4A MYO15A	6.12e-03	50	139	3	PS00660
Domain	FERM_2	EPB41L3 FRMD4A MYO15A	6.12e-03	50	139	3	PS00661
Domain	FERM_3	EPB41L3 FRMD4A MYO15A	6.12e-03	50	139	3	PS50057
Domain	Band_41_domain	EPB41L3 FRMD4A MYO15A	6.12e-03	50	139	3	IPR019749
Domain	B41	EPB41L3 FRMD4A MYO15A	6.12e-03	50	139	3	SM00295
Domain	DENN	DENND2B SBF1	6.16e-03	16	139	2	SM00799
Domain	SEC7	PSD ARFGEF2	6.16e-03	16	139	2	PS50190
Domain	DENN	DENND2B SBF1	6.16e-03	16	139	2	PF02141
Domain	dDENN	DENND2B SBF1	6.16e-03	16	139	2	PF03455
Domain	Sec7	PSD ARFGEF2	6.16e-03	16	139	2	SM00222
Domain	UDENN	DENND2B SBF1	6.16e-03	16	139	2	PS50946
Domain	DDENN	DENND2B SBF1	6.16e-03	16	139	2	PS50947
Domain	Sulfatase_CS	ARSB SULF1	6.16e-03	16	139	2	IPR024607
Domain	dDENN	DENND2B SBF1	6.16e-03	16	139	2	SM00801
Domain	dDENN_dom	DENND2B SBF1	6.16e-03	16	139	2	IPR005112
Domain	uDENN_dom	DENND2B SBF1	6.16e-03	16	139	2	IPR005113
Domain	Sec7_dom	PSD ARFGEF2	6.16e-03	16	139	2	IPR000904
Domain	DENN	DENND2B SBF1	6.16e-03	16	139	2	PS50211
Domain	DENN_dom	DENND2B SBF1	6.16e-03	16	139	2	IPR001194
Domain	SULFATASE_1	ARSB SULF1	6.95e-03	17	139	2	PS00523
Domain	PBD	CDC42BPG PAK4	6.95e-03	17	139	2	PF00786
Domain	SULFATASE_2	ARSB SULF1	6.95e-03	17	139	2	PS00149
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	MYC BRPF3 ERCC6 ATXN7L2 PSD EP400 DDX52 WRNIP1 OAS3 XPC INO80 RAB11FIP1 EPB41L3 GJD4 CEP170 NCOR2 FOXP4 ZNF469 ZNF526 TRAFD1 ARSB ZFHX4 MCM3AP TTC39A TOP2A TP53 PRRC2B	2.45e-13	1116	148	27	31753913
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	PRPF31 RBM15 EXPH5 PAK4 RAB11FIP1 EPB41L3 PRAG1 DENND2B CEP350 CEP170 ZCCHC14 USP31 NF1 SBF1 PHF3 N4BP2 TBC1D1 CDC25B TP53	5.25e-09	861	148	19	36931259
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ROCK2 RBM15 EP400 WRNIP1 ARFGEF2 XPC NCOR2 TRAFD1 NF1 STC2 PHF3 ASPH SORBS3 RBM15B PLCB3 TOP2A TOP2B	3.81e-08	774	148	17	15302935
Pubmed	Human topoisomerase IIalpha and IIbeta interact with the C-terminal region of p53.	TOP2A TOP2B TP53	7.55e-08	3	148	3	10666337
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3 RIMBP3C RIMBP3B	3.01e-07	4	148	3	19091768
Pubmed	Interaction of the Epstein-Barr virus mRNA export factor EB2 with human Spen proteins SHARP, OTT1, and a novel member of the family, OTT3, links Spen proteins with splicing regulation and mRNA export.	RBM15 NCOR2 RBM15B	3.01e-07	4	148	3	16129689
Pubmed	Impaired genome maintenance suppresses the growth hormone--insulin-like growth factor 1 axis in mice with Cockayne syndrome.	ERCC6 XPC TP53	3.01e-07	4	148	3	17326724
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	MYC PRPF31 RBM15 ATXN7L2 EP400 DDX52 ZNF205 XPC INO80 THAP4 NCOR2 ZIC5 PHF3 ASPH RBM15B NFXL1 TMEM41B TOP2A TOP2B C1orf174	6.60e-07	1294	148	20	30804502
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	RIMBP3 RIMBP3C RIMBP3B	7.50e-07	5	148	3	17855024
Pubmed	Aldehyde-driven transcriptional stress triggers an anorexic DNA damage response.	ERCC6 XPC TP53	1.50e-06	6	148	3	34819667
Pubmed	Nucleophosmin and its AML-associated mutant regulate c-Myc turnover through Fbw7 gamma.	MYC NFATC1 TP53	2.61e-06	7	148	3	18625840
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	PRPF31 PAK4 DVL3 XPC INO80 FNBP1L EPB41L3 CEP350 CEP170 SBF1 PHF3 NFXL1 TOP2B PRRC2B	2.86e-06	724	148	14	36232890
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	RBM15 MYOM1 PNMA8B CEP170 NF1 ZFHX4 PHF3 ASL RBM15B PRRC2B	3.68e-06	361	148	10	26167880
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	PRPF31 RBM15 EP400 XPC INO80 FLG2 EPB41L3 ZC3H6 CEP170 SBF1 SPIN1 RBM15B FBXO45 PBXIP1 TOP2B C1orf174 SPIN3	3.92e-06	1082	148	17	38697112
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	MYC PRPF31 RBM15 ERCC6 EP400 MBOAT7 DDX52 OAS3 XPC EPB41L3 NCOR2 ALKBH1 NF1 SBF1 MCM3AP ASPH NFXL1 TOP2A TOP2B	5.16e-06	1353	148	19	29467282
Pubmed	Notch3 interactome analysis identified WWP2 as a negative regulator of Notch3 signaling in ovarian cancer.	MYC GGT6 SORBS3 TMEM108	5.95e-06	28	148	4	25356737
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	PRPF31 EP400 WRNIP1 FLG2 EPB41L3 HOXA5 ZFHX4 NFATC1 ZIC5 PHF3 SPIN1 TP53	8.12e-06	583	148	12	29844126
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	ZFP42 COL13A1 ZC3H6 CEP350 THAP4 SBF1 NFATC1 PHF3 TBC1D1 RIMBP3C SENP2 TP53 PRRC2B	8.55e-06	689	148	13	36543142
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ROCK2 ADAMTS4 EXPH5 PLEKHA6 EPB41L3 CEP350 CEP170 ZNF526 N4BP2 TTC39A TMEM41B	9.29e-06	493	148	11	15368895
Pubmed	Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression.	DNAJB12 RBM15 ERCC6 OAS3 TRAFD1 SPIN1 ASPH SORBS3 TOP2A PRRC2B	9.62e-06	403	148	10	35253629
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	EP400 ZCCHC14 USP31 MAGI2 PHF3 TBC1D1 MCM3AP SENP2 PRRC2B PDZD2	1.05e-05	407	148	10	12693553
Pubmed	CIB2 interacts with TMC1 and TMC2 and is essential for mechanotransduction in auditory hair cells.	EPS8L2 TMC2 MYO15A	1.62e-05	12	148	3	28663585
Pubmed	DNA topoisomerase II is dispensable for oocyte meiotic resumption but is essential for meiotic chromosome condensation and separation in mice.	TOP2A TOP2B	1.80e-05	2	148	2	24048577
Pubmed	Study of Association between Pre-Senile Cataracts and the Polymorphisms rs2228000 in XPC and rs1042522 in p53 in Spanish Population.	XPC TP53	1.80e-05	2	148	2	27248495
Pubmed	Use of divalent metal ions in the dna cleavage reaction of human type II topoisomerases.	TOP2A TOP2B	1.80e-05	2	148	2	19222228
Pubmed	Characterization of cDNA encoding the mouse DNA topoisomerase II that can complement the budding yeast top2 mutation.	TOP2A TOP2B	1.80e-05	2	148	2	1331984
Pubmed	Expression of p53, Ki-67 and c-Myc proteins is predictive of the surgical molecular margin in colorectal carcinoma.	MYC TP53	1.80e-05	2	148	2	21298377
Pubmed	Mediation of c-Myc-induced apoptosis by p53.	MYC TP53	1.80e-05	2	148	2	8091232
Pubmed	Knockdown of DEAD-box RNA helicase 52 (DDX52) suppresses the proliferation of melanoma cells in vitro and of nude mouse xenografts by targeting c-Myc.	MYC DDX52	1.80e-05	2	148	2	34233596
Pubmed	HOXA5 counteracts the function of pathological scar-derived fibroblasts by partially activating p53 signaling.	HOXA5 TP53	1.80e-05	2	148	2	33414417
Pubmed	MYC is Sufficient to Generate Mid-Life High-Grade Serous Ovarian and Uterine Serous Carcinomas in a p53-R270H Mouse Model.	MYC TP53	1.80e-05	2	148	2	39225558
Pubmed	Overexpression of p53 protein is a marker of poor prognosis in Mexican women with breast cancer.	TOP2A TP53	1.80e-05	2	148	2	28393224
Pubmed	Different patterns of gene expression of topoisomerase II isoforms in differentiated tissues during murine development.	TOP2A TOP2B	1.80e-05	2	148	2	1380833
Pubmed	Induction of p53-independent apoptosis by ectopic expression of HOXA5 in human liposarcomas.	HOXA5 TP53	1.80e-05	2	148	2	26219418
Pubmed	Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants.	MYC TP53	1.80e-05	2	148	2	16094360
Pubmed	Loss of p53 function leads to metastasis in ras+myc-initiated mouse prostate cancer.	MYC TP53	1.80e-05	2	148	2	7534899
Pubmed	MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism.	MYC TP53	1.80e-05	2	148	2	25964345
Pubmed	Low NCOR2 levels in multiple myeloma patients drive multidrug resistance via MYC upregulation.	MYC NCOR2	1.80e-05	2	148	2	34864816
Pubmed	Synergistic interactions between XPC and p53 mutations in double-mutant mice: neural tube abnormalities and accelerated UV radiation-induced skin cancer.	XPC TP53	1.80e-05	2	148	2	8994835
Pubmed	The role of AMP-activated protein kinase in the expression of the dystrophin-associated protein complex in skeletal muscle.	PRKAB1 PRKAB2	1.80e-05	2	148	2	29401588
Pubmed	Susceptibility to astrocytoma in mice mutant for Nf1 and Trp53 is linked to chromosome 11 and subject to epigenetic effects.	NF1 TP53	1.80e-05	2	148	2	15319471
Pubmed	Characterization and immunological identification of cDNA clones encoding two human DNA topoisomerase II isozymes.	TOP2A TOP2B	1.80e-05	2	148	2	2556712
Pubmed	PAK4 Phosphorylates p53 at Serine 215 to Promote Liver Cancer Metastasis.	PAK4 TP53	1.80e-05	2	148	2	27496712
Pubmed	HOXA5 inhibits the proliferation and neoplasia of cervical cancer cells via downregulating the activity of the Wnt/β-catenin pathway and transactivating TP53.	HOXA5 TP53	1.80e-05	2	148	2	32499530
Pubmed	Reciprocally regulated chromatin association of Cockayne syndrome protein B and p53 protein.	ERCC6 TP53	1.80e-05	2	148	2	21852235
Pubmed	Roles of DNA topoisomerase II isozymes in chemotherapy and secondary malignancies.	TOP2A TOP2B	1.80e-05	2	148	2	17578914
Pubmed	Noncoding RNAs Regulating p53 and c-Myc Signaling.	MYC TP53	1.80e-05	2	148	2	27376742
Pubmed	Somatic cell transfer of c-Myc and Bcl-2 induces large-cell anaplastic medulloblastomas in mice.	MYC TP53	1.80e-05	2	148	2	26518543
Pubmed	AMPKβ1 and AMPKβ2 define an isoform-specific gene signature in human pluripotent stem cells, differentially mediating cardiac lineage specification.	PRKAB1 PRKAB2	1.80e-05	2	148	2	33454005
Pubmed	Overexpression of MYC causes p53-dependent G2 arrest of normal fibroblasts.	MYC TP53	1.80e-05	2	148	2	10962037
Pubmed	Phosphorylation of p53 serine 18 upregulates apoptosis to suppress Myc-induced tumorigenesis.	MYC TP53	1.80e-05	2	148	2	20145032
Pubmed	MYC and TP53 Alterations but Not MAPK Pathway Mutations Are Common Oncogenic Mechanisms in Follicular Dendritic Cell Sarcomas.	MYC TP53	1.80e-05	2	148	2	36355424
Pubmed	Selective cell death of p53-insufficient cancer cells is induced by knockdown of the mRNA export molecule GANP.	MCM3AP TP53	1.80e-05	2	148	2	22395445
Pubmed	MYC Expression Is Associated With p53 Expression and TP53 Aberration and Predicts Poor Overall Survival in Acute Lymphoblastic Leukemia/Lymphoma.	MYC TP53	1.80e-05	2	148	2	34528662
Pubmed	Oncogenic MYC Induces the Impaired Ribosome Biogenesis Checkpoint and Stabilizes p53 Independent of Increased Ribosome Content.	MYC TP53	1.80e-05	2	148	2	31292158
Pubmed	Genetic variation in the nucleotide excision repair pathway and colorectal cancer risk.	ERCC6 XPC	1.80e-05	2	148	2	17119055
Pubmed	Chr 19(A/J) modifies tumor resistance in a sex- and parent-of-origin-specific manner.	NF1 TP53	1.80e-05	2	148	2	19347398
Pubmed	Molecular cloning and characterization of the human topoisomerase IIalpha and IIbeta genes: evidence for isoform evolution through gene duplication.	TOP2A TOP2B	1.80e-05	2	148	2	10095062
Pubmed	Cotargeting MNK and MEK kinases induces the regression of NF1-mutant cancers.	NF1 TP53	1.80e-05	2	148	2	27159396
Pubmed	Persistence of p53 mutations and resistance of keratinocytes to apoptosis are associated with the increased susceptibility of mice lacking the XPC gene to UV carcinogenesis.	XPC TP53	1.80e-05	2	148	2	10602497
Pubmed	Functional compatibility between isoform alpha and beta of type II DNA topoisomerase.	TOP2A TOP2B	1.80e-05	2	148	2	14996935
Pubmed	Myc/p53 interactions in transgenic mouse mammary development, tumorigenesis and chromosomal instability.	MYC TP53	1.80e-05	2	148	2	9652742
Pubmed	Insertional mutagenesis and deep profiling reveals gene hierarchies and a Myc/p53-dependent bottleneck in lymphomagenesis.	MYC TP53	1.80e-05	2	148	2	24586197
Pubmed	Natural variation in a single amino acid substitution underlies physiological responses to topoisomerase II poisons.	TOP2A TOP2B	1.80e-05	2	148	2	28700616
Pubmed	Predictors and mechanisms of epilepsy occurrence in cerebral gliomas: What to look for in clinicopathology.	TOP2A TOP2B	1.80e-05	2	148	2	28087392
Pubmed	Roles of the C-terminal domains of topoisomerase IIα and topoisomerase IIβ in regulation of the decatenation checkpoint.	TOP2A TOP2B	1.80e-05	2	148	2	28472494
Pubmed	Hepatitis C virus F protein up-regulates c-myc and down-regulates p53 in human hepatoma HepG2 cells.	MYC TP53	1.80e-05	2	148	2	17700029
Pubmed	Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma.	NF1 TP53	1.80e-05	2	148	2	16098465
Pubmed	MYC-driven malignant transformation of mature murine B cells requires inhibition of both intrinsic apoptosis and p53 activity.	MYC TP53	1.80e-05	2	148	2	30281155
Pubmed	SRC Increases MYC mRNA Expression in Estrogen Receptor-Positive Breast Cancer via mRNA Stabilization and Inhibition of p53 Function.	MYC TP53	1.80e-05	2	148	2	29263157
Pubmed	Substrate Stiffness Influences Doxorubicin-Induced p53 Activation via ROCK2 Expression.	ROCK2 TP53	1.80e-05	2	148	2	28191463
Pubmed	The autocrine human secreted PDZ domain-containing protein 2 (sPDZD2) induces senescence or quiescence of prostate, breast and liver cancer cells via transcriptional activation of p53.	TP53 PDZD2	1.80e-05	2	148	2	18639375
Pubmed	The distribution and expression of the two isoforms of DNA topoisomerase II in normal and neoplastic human tissues.	TOP2A TOP2B	1.80e-05	2	148	2	9155056
Pubmed	Combined use of nuclear phosphoprotein c-Myc and cellular phosphoprotein p53 for hepatocellular carcinoma detection in high-risk chronic hepatitis C patients.	MYC TP53	1.80e-05	2	148	2	28705056
Pubmed	Selection and dynamics of embryonic stem cell integration into early mouse embryos.	MYC ZFP42	1.80e-05	2	148	2	26586221
Pubmed	Gene expression profiling of p53 and c-myc in HTLV-1 positive blood donors in Congo.	MYC TP53	1.80e-05	2	148	2	38843019
Pubmed	cMyc-p53 feedback mechanism regulates the dynamics of T lymphocytes in the immune response.	MYC TP53	1.80e-05	2	148	2	26985633
Pubmed	Influence of Hoxa5 on p53 tumorigenic outcome in mice.	HOXA5 TP53	1.80e-05	2	148	2	20042682
Pubmed	Dysmyelination not demyelination causes neurological symptoms in preweaned mice in a murine model of Cockayne syndrome.	ERCC6 XPC	1.80e-05	2	148	2	22393014
Pubmed	NFATC1 promotes cell growth and tumorigenesis in ovarian cancer up-regulating c-Myc through ERK1/2/p38 MAPK signal pathway.	MYC NFATC1	1.80e-05	2	148	2	26501422
Pubmed	An imprinted locus epistatically influences Nstr1 and Nstr2 to control resistance to nerve sheath tumors in a neurofibromatosis type 1 mouse model.	NF1 TP53	1.80e-05	2	148	2	16397217
Pubmed	Pro-905, a Novel Purine Antimetabolite, Combines with Glutamine Amidotransferase Inhibition to Suppress Growth of Malignant Peripheral Nerve Sheath Tumor.	NF1 TP53	1.80e-05	2	148	2	37616542
Pubmed	Active heterodimers are formed from human DNA topoisomerase II alpha and II beta isoforms.	TOP2A TOP2B	1.80e-05	2	148	2	8710863
Pubmed	Cytomegalovirus contributes to glioblastoma in the context of tumor suppressor mutations.	NF1 TP53	1.80e-05	2	148	2	23729642
Pubmed	Increased H2O2 levels and p53 stabilization lead to mitochondrial dysfunction in XPC-deficient cells.	XPC TP53	1.80e-05	2	148	2	34447990
Pubmed	Wild-type p53 binds to MYC promoter G-quadruplex.	MYC TP53	1.80e-05	2	148	2	27634752
Pubmed	Tumor suppressor p53 dependent recruitment of nucleotide excision repair factors XPC and TFIIH to DNA damage.	XPC TP53	1.80e-05	2	148	2	12713809
Pubmed	AMPK-Regulated Astrocytic Lactate Shuttle Plays a Non-Cell-Autonomous Role in Neuronal Survival.	PRKAB1 PRKAB2	1.80e-05	2	148	2	32877674
Pubmed	Regulation of HSulf-1 expression by variant hepatic nuclear factor 1 in ovarian cancer.	HNF1B SULF1	1.80e-05	2	148	2	19487294
Pubmed	Sympathetic neuron survival and proliferation are prolonged by loss of p53 and neurofibromin.	NF1 TP53	1.80e-05	2	148	2	9608530
Pubmed	ADAMTS4 exacerbates lung cancer progression via regulating c-Myc protein stability and activating MAPK signaling pathway.	MYC ADAMTS4	1.80e-05	2	148	2	39415271
Pubmed	Mutational inactivation of the xeroderma pigmentosum group C gene confers predisposition to 2-acetylaminofluorene-induced liver and lung cancer and to spontaneous testicular cancer in Trp53-/- mice.	XPC TP53	1.80e-05	2	148	2	10029060
Pubmed	Evidence for a mutant allele of the gene for DNA topoisomerase II in adriamycin-resistant P388 murine leukemia cells.	TOP2A TOP2B	1.80e-05	2	148	2	2555055
Pubmed	p53-Dependent transcriptional repression of c-myc is required for G1 cell cycle arrest.	MYC TP53	1.80e-05	2	148	2	16107691
Pubmed	Doxorubicin-induced cardiotoxicity is maturation dependent due to the shift from topoisomerase IIα to IIβ in human stem cell derived cardiomyocytes.	TOP2A TOP2B	1.80e-05	2	148	2	31106979
Pubmed	A biochemical analysis of topoisomerase II alpha and beta kinase activity found in HIV-1 infected cells and virus.	TOP2A TOP2B	1.80e-05	2	148	2	16091284
Pubmed	AMPK deficiency in cardiac muscle results in dilated cardiomyopathy in the absence of changes in energy metabolism.	PRKAB1 PRKAB2	1.80e-05	2	148	2	26023060
Pubmed	A p53 defect sensitizes various stages of B cell development to lymphomagenesis in mice carrying an IgH 3' regulatory region-driven c-myc transgene.	MYC TP53	1.80e-05	2	148	2	22039300
Pubmed	Both c-Myc and Ki-67 expression are predictive markers in patients with extranodal NK/T-cell lymphoma, nasal type: a retrospective study in China.	MYC TP53	1.80e-05	2	148	2	24642368
Pubmed	Clinicopathologic and Molecular Characterization of Anorectal Neuroendocrine Carcinomas Reveals Human Papillomavirus, p53, and c-Myc as Alternative Mechanisms of Carcinogenesis.	MYC TP53	1.80e-05	2	148	2	37517480
Interaction	EGR2 interactions	EP400 INO80 FLG2 NCOR2 FOXP4 ZFHX4 NFATC1 RBM15B PRRC2B	3.94e-06	171	144	9	int:EGR2
Interaction	YWHAH interactions	CDC42BPG RBM15 EXPH5 PAK4 RAB11FIP1 EPB41L3 PRAG1 PLEKHG5 DENND2B CEP350 CEP170 ZCCHC14 USP31 FRMD4A NF1 GRID2IP SBF1 PHF3 TBC1D1 RBM15B CDC25B FBXO45	1.17e-05	1102	144	22	int:YWHAH
GeneFamily	Tudor domain containing\|Spindlin family	SPIN1 SPIN3	2.48e-04	5	91	2	1089
GeneFamily	Topoisomerases	TOP2A TOP2B	3.71e-04	6	91	2	1050
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ROCK2 CDC42BPG PSD PLEKHA6 PLEKHG5 SBF1	6.07e-04	206	91	6	682
GeneFamily	PDZ domain containing	DVL3 MAGI2 GRID2IP GRIP2 PDZD2	1.02e-03	152	91	5	1220
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	EPB41L3 FRMD4A MYO15A	2.04e-03	50	91	3	1293
GeneFamily	AT-rich interaction domain containing	ARID5A JARID2	2.52e-03	15	91	2	418
GeneFamily	Sulfatases	ARSB SULF1	3.64e-03	18	91	2	410
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ATXN7L2 MORN1 CAPS CHST6 PLEKHA6 C16orf46 GRID2IP	1.31e-06	164	148	7	9e16e52f5a634585f26021bcce9b5d5992ff6db0
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAK4 DVL3 PLEKHA6 FRMD4A ARSB SLC39A6 TMEM108	2.52e-06	181	148	7	4e81ec1580e9acb22c32c465eb46f83d1e9e424e
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAK4 DVL3 PLEKHA6 FRMD4A ARSB SLC39A6 TMEM108	2.52e-06	181	148	7	ad30c01290fb98adbd0caed301a584761212c977
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAK4 DVL3 PLEKHA6 FRMD4A ARSB SLC39A6 TMEM108	2.52e-06	181	148	7	3a3268a4dff8ffcb79e09f46490e138c96f8d916
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	DNAJB12 THSD1 RAB11FIP1 C16orf46 PRKAB2 CCDC24 PBXIP1	4.86e-06	200	148	7	be83f442179ba4217d12f0458059586ff3130991
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PSD USP31 SHF FMN1 SPANXA2-OT1 PLCB3	6.06e-06	135	148	6	0e5dfbe79598fc7822a7b3baa8d7dba3c9da1dad
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Lymphocytic-T_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYC FOXP4 NFATC1 RINL ARHGAP45 TOP2A	1.60e-05	160	148	6	cfd005e98944817458e8ef9e0c436d77f50c1ad1
Drug	2,4,4'-trichlorobiphenyl	PRPF31 CACNA1F ZFP42 EPS8L2 ATXN7L2 PSD EP400 GGT6 DVL3 PLEKHA6 FNBP1L USP31 FRMD4A ZNF526 ZFHX4 SPIN1 CCDC74A ASPH SEBOX PRDM13 TTC39A CDC25B KISS1 TOP2A TP53	3.39e-06	1411	146	25	ctd:C081766
Drug	Pyrilamine maleate [59-33-6]; Down 200; 10uM; MCF7; HT_HG-U133A	EP400 ZNF205 THSD1 ZCCHC14 NF1 SULF1 MCM3AP SORBS3 PBXIP1	4.65e-06	194	146	9	3184_DN
Drug	ICI182,780; Down 200; 1uM; MCF7; HT_HG-U133A	MYC ZNF205 THSD1 DENND2B FRMD4A TRAFD1 STC2 MCM3AP PRKG2	4.65e-06	194	146	9	7534_DN
Drug	Ebselen [60940-34-3]; Down 200; 14.6uM; MCF7; HT_HG-U133A	DNAJB12 ZNF205 THSD1 SULF1 ASL MCM3AP PLCB3 ARHGAP45 PBXIP1	4.85e-06	195	146	9	3458_DN
Drug	2,4,5,2',5'-pentachlorobiphenyl	PRPF31 CACNA1F ZFP42 EPS8L2 ATXN7L2 PSD EP400 GGT6 DVL3 PLEKHA6 FNBP1L USP31 FRMD4A ZNF526 ZFHX4 SPIN1 CCDC74A ASPH SEBOX PRDM13 TTC39A CDC25B KISS1 TOP2A TP53	4.90e-06	1441	146	25	ctd:C009828
Drug	Amsacrine	MYC TOP2A TOP2B TP53	2.95e-05	28	146	4	ctd:D000677
Drug	geldanamycin; Down 200; 1uM; HL60; HT_HG-U133A	MYC FJX1 ARID5A RPP25 NFATC1 STC2 PRDM13 PLCB3	2.97e-05	188	146	8	6187_DN
Drug	PHA-00846566E [724718-26-7]; Down 200; 10uM; PC3; HT_HG-U133A	DNAJB12 HNF1B TEDC2 CEP350 TRAFD1 SBF1 STC2 TTC39A	3.33e-05	191	146	8	7086_DN
Drug	CP-944629 [668990-94-1]; Down 200; 10uM; MCF7; HT_HG-U133A	ROCK2 COL13A1 MORN1 MBOAT7 EXPH5 COX6A2 MCM3AP SORBS3	3.58e-05	193	146	8	7497_DN
Drug	5155877; Up 200; 10uM; PC3; HT_HG-U133A	MYC ROCK2 TEDC2 CEP350 SBF1 STC2 SLC39A6 LRRN2	3.86e-05	195	146	8	6569_UP
Drug	norkurarinol	ERCC6 XPC	4.08e-05	2	146	2	ctd:C572712
Drug	Dexrazoxane	TOP2A TOP2B	4.08e-05	2	146	2	DB00380
Drug	kurarinone	ERCC6 XPC	4.08e-05	2	146	2	ctd:C411319
Drug	ascaridole	ERCC6 XPC	4.08e-05	2	146	2	ctd:C043372
Drug	Carbazoles	ERCC6 XPC	4.08e-05	2	146	2	ctd:D002227
Drug	F14512	TOP2A TOP2B	4.08e-05	2	146	2	ctd:C534191
Drug	Daunorubicin	TOP2A TOP2B	4.08e-05	2	146	2	DB00694
Drug	Captopril [62571-86-2]; Up 200; 17.2uM; MCF7; HT_HG-U133A	MORN1 PRR36 CEP350 NCOR2 NF1 ZFHX4 TTC39A PBXIP1	4.30e-05	198	146	8	4410_UP
Drug	BAS 012416453; Up 200; 38uM; PC3; HT_HG-U133A	ROCK2 ZNF205 CCDC57 MAGI2 NF1 NFATC1 PHF3 MCM3AP	4.45e-05	199	146	8	6876_UP
Drug	0317956-0000 [391210-11-0]; Up 200; 1uM; PC3; HT_HG-U133A	DNAJB12 COX6A2 NF1 SULF1 PHF3 MCM3AP ASPH PRKAB2	4.45e-05	199	146	8	4334_UP
Drug	N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Up 200; 25.2uM; PC3; HT_HG-U133A	COX6A2 WRNIP1 DVL3 NCOR2 SULF1 SORBS3 PRKG2 PBXIP1	4.45e-05	199	146	8	4311_UP
Drug	formylglycine	ENPP3 MBP ARSB SULF1	5.75e-05	33	146	4	CID000075606
Disease	B cell deficiency (implicated_via_orthology)	TOP2A TOP2B	2.17e-05	2	138	2	DOID:2115 (implicated_via_orthology)
Disease	uric acid measurement	CDC42BPG PLEKHA6 FNBP1L EPB41L3 TRAFD1 SHF NFATC1 FMN1 SPIN1 SELENOO SENP2 PRRC2B	3.13e-05	610	138	12	EFO_0004761
Disease	Disease Exacerbation	MYC XPC PRKAB1 CRYBG1 TOP2A TP53	1.30e-04	165	138	6	C0235874
Disease	urinary bladder cancer (is_marker_for)	MYC CDC25B KISS1 TOP2A TP53	1.51e-04	107	138	5	DOID:11054 (is_marker_for)
Disease	esophageal disease	HNF1B DDX52	2.15e-04	5	138	2	EFO_0009544
Disease	clear cell renal cell carcinoma (is_marker_for)	MYC PAK4 TP53	4.93e-04	33	138	3	DOID:4467 (is_marker_for)
Disease	Malignant neoplasm of breast	ERCC6 AVPR2 DVL3 ARFGEF2 EPB41L3 ZCCHC14 FOXP4 NF1 STC2 N4BP2 ASL SLC39A6 TOP2A TP53	5.26e-04	1074	138	14	C0006142
Disease	endometrial carcinoma (is_marker_for)	NCOR2 KISS1 TP53	5.39e-04	34	138	3	DOID:2871 (is_marker_for)
Disease	Malignant neoplasm of liver	MYC XPC TTC39A TOP2A TP53	5.58e-04	142	138	5	C0345904
Disease	Liver neoplasms	MYC XPC TTC39A TOP2A TP53	5.58e-04	142	138	5	C0023903
Disease	Clinically Isolated Syndrome, CNS Demyelinating	MBP TP53	5.97e-04	8	138	2	C2350037
Disease	Demyelinating Diseases	MBP TP53	5.97e-04	8	138	2	C0011303
Disease	Demyelination	MBP TP53	5.97e-04	8	138	2	C0011304
Disease	renin measurement	PLEKHA6 LRRN2	5.97e-04	8	138	2	EFO_0010616
Disease	hemorrhoid	FRMD4A NF1 LRRN2 MYO15A TP53	6.53e-04	147	138	5	EFO_0009552
Disease	Cutaneous Melanoma	XPC NF1 TP53	9.37e-04	41	138	3	C0151779
Disease	Uterine leiomyoma, estrogen-receptor negative breast cancer	EXPH5 TP53	9.53e-04	10	138	2	EFO_1000650, HP_0000131
Disease	aortic valve stenosis (is_marker_for)	JARID2 NFATC1	1.16e-03	11	138	2	DOID:1712 (is_marker_for)
Disease	Ductal Carcinoma	MYC TP53	1.16e-03	11	138	2	C1176475
Disease	folic acid measurement	MORN1 MAGI2 MYO15A	1.31e-03	46	138	3	EFO_0005111
Disease	acute myeloid leukemia (implicated_via_orthology)	TOP2A TOP2B	1.39e-03	12	138	2	DOID:9119 (implicated_via_orthology)
Disease	Squamous cell carcinoma of the head and neck	HOXA5 KISS1 TP53	1.87e-03	52	138	3	C1168401
Disease	diacylglycerol 38:4 measurement	PRPF31 MBOAT7	1.90e-03	14	138	2	EFO_0020066
Disease	Sarcoma, Spindle Cell	NF1 TP53	1.90e-03	14	138	2	C0205945
Disease	Sarcoma, Epithelioid	NF1 TP53	1.90e-03	14	138	2	C0205944
Disease	R-6-hydroxywarfarin measurement	RBM15 ZFP42 NCOR2 SELENOO	2.05e-03	114	138	4	EFO_0803327
Disease	Hypertrophic Cardiomyopathy	MYC MYOM1 TP53	2.44e-03	57	138	3	C0007194
Disease	theta wave measurement	MBP FRMD4A	2.82e-03	17	138	2	EFO_0006873
Disease	red blood cell density measurement	EP400 ARFGEF2 INO80 FNBP1L RBBP8NL DENND2B FRMD4A FMN1 FAM222B PLCB3 MYO15A	2.90e-03	880	138	11	EFO_0007978
Disease	Adrenocortical carcinoma	TOP2A TP53	3.16e-03	18	138	2	C0206686
Disease	Hemangiosarcoma	MYC TP53	3.16e-03	18	138	2	C0018923
Disease	diacylglycerol 38:3 measurement	PRPF31 MBOAT7	3.52e-03	19	138	2	EFO_0020065
Disease	Pheochromocytoma	NF1 TP53	3.52e-03	19	138	2	C0031511
Disease	ovarian neoplasm	MYC ERCC6 SULF1 TP53	3.68e-03	134	138	4	C0919267
Disease	Malignant neoplasm of ovary	MYC ERCC6 SULF1 TP53	3.98e-03	137	138	4	C1140680
Disease	Sarcoma	NF1 TP53	4.30e-03	21	138	2	C1261473
Disease	Malignant Glioma	NF1 TOP2A TP53	4.36e-03	70	138	3	C0555198
Disease	mixed gliomas	NF1 TOP2A TP53	4.36e-03	70	138	3	C0259783
Disease	diastolic blood pressure, systolic blood pressure	BRPF3 RBBP8NL DENND2B CEP350 ZIC5 N4BP2 TBC1D1 FAM222B TP53	4.36e-03	670	138	9	EFO_0006335, EFO_0006336

Protein segments in the cluster

Peptide	Gene	Start	Entry
TKSGGGRCAIHPRRS	CEP295NL	231	Q96MC4
LVHSKTPEGNNGRSG	CEP170	1371	Q5SW79
HGRELLASAPTGSGK	DDX52	201	Q9Y2R4
GRRGKEAGPAHSYTS	EP400	1791	Q96L91
GDANRPSAFHKGGSR	ARID5A	391	Q03989
GVYSGRAHPKVRSGE	CAPS	206	Q13938
KAGSRTASPGAPGAH	CXorf49;	21	A8MYA2
FSAAHAARGKGPGAQ	ALKBH1	46	Q13686
NNSGAPHREKRGGET	ACBD5	386	Q5T8D3
HKREGSGRFSLPGAT	GSDMD	176	P57764
GSGREREGSLKGHTL	ARFGEF2	1016	Q9Y6D5
HSPPGAATARRKGDS	BRPF3	386	Q9ULD4
GERHGAKAARSEGAG	PRKAB2	11	O43741
AKAARSEGAGGHAPG	PRKAB2	16	O43741
KGARSPGSTHQGSLA	ARL17A	86	Q8IVW1
GSSSPGARRETKHGG	ASPH	26	Q12797
ITHGAGGTKAPRGTL	DENND2B	11	P78524
GPEHATRLNGTAKGE	DVL3	151	Q92997
KEGSSRTHRPGGKRG	CCDC74A	136	Q96AQ1
GHRGISGAPAGKKSR	ERCC6	1316	Q03468
PKAGTGAGTRHSAQP	ARMCX4	1016	Q5H9R4
SREKGQGSRSRGHQP	ATXN7L2	146	Q5T6C5
GEAGSAGKNSGRHRA	ANKRD63	231	C9JTQ0
AGKNSGRHRAQGSER	ANKRD63	236	C9JTQ0
NRGKASGNPSGGAHR	C16orf46	181	Q6P387
EAGGRRAAHKASGGA	RBM15B	31	Q8NDT2
ASGGAKHPVPARARD	RBM15B	41	Q8NDT2
GKTDSGGGSRRSLHL	RBM15	86	Q96T37
HRKLSNPRGGEGSES	RIMBP3B	341	A6NNM3
HRKLSNPRGGEGSES	RIMBP3C	341	A6NJZ7
LTLPGAEAGAHGSRR	FMN1	371	Q68DA7
HSARSRGRPKGSGST	INO80	1426	Q9ULG1
AKDPGISGEATRHGG	CDC42BPG	826	Q6DT37
DSLHKKAGGRSRGGL	MORN1	386	Q5T089
GASGLGTPKRRNQHS	CACNA1F	41	O60840
ARGSPHSEGGKRSPE	NCOR2	2191	Q9Y618
SGGKDRHGSSSVELR	FLG2	191	Q5D862
EGTPAKDHRAGRGHQ	ARHGAP45	601	Q92619
ARAGGKEAPRAAAGS	MAGI2	1361	Q86UL8
RGRATAAPSGNGVHL	NFXL1	16	Q6ZNB6
GSQKARAGGPAVREA	MYO15A	591	Q9UKN7
GQGATALARLPRGTH	LRRN2	566	O75325
GATAGKLHTGRSRND	ASL	101	P04424
QHSPLGKAAGRTGAS	MCM3AP	536	O60318
KRAFSGQGLHEGPAR	KCNT1	626	Q5JUK3
GGGAGRRTSKAQRVH	C20orf203	61	Q8NBC4
IRKQSGASGHAEGRR	GJD4	236	Q96KN9
IQVSGGRGSKRSPHA	PDZD2	346	O15018
PGLTGKHAAGRELAG	FAM222B	386	Q8WU58
SHDNIGGPEGKRART	HOXA5	186	P20719
GSRGAVKASAGGHPI	NFATC1	446	O95644
FGKREAAPGNHGRSA	KISS1	121	Q15726
ALGGGSPSRRKAASQ	MBOAT7	446	Q96N66
APDGRRKSEAGSGAA	CDC25B	171	P30305
PSGEPHASTGREGRK	EXPH5	1126	Q8NEV8
SLHGGGPARRRSSDK	FOXP4	431	Q8IVH2
TESGRLFKGKRAHGP	F8	986	P00451
KDAQAGKEPGGSRAH	TP53	351	P04637
TPGGLFRSHNGKSRE	DEFB116	21	Q30KQ4
QHRGGDSPEAKNRVG	EPS8L2	211	Q9H6S3
HSRRGAKAGVSAEPT	PRKG2	116	Q13237
GRSKAVLLRSGGLHG	SBF1	1201	O95248
VSSSGKRAREVHGGQ	NUTM1	526	Q86Y26
HRPSAGGPDSAGRKR	PLCB3	471	Q01970
RATSNLHRGPGGALV	FJX1	321	Q86VR8
LAAAGLSGGRHTQPA	RBBP8NL	406	Q8NC74
TPSLGREGAHDKGAG	FRMD4A	906	Q9P2Q2
NSAGGPGAHILRRKS	ADAMTS4	171	O75173
AGPRRGSGHQSKTNR	CCDC71	246	Q8IV32
EVAKGSSAHAGGLRP	GRID2IP	31	A4D2P6
GVASGHLPRKGSGSD	BSPRY	301	Q5W0U4
HRPRGGRGKASPTSF	C5orf60	146	A6NFR6
EGKTGGRGDRRHSSD	FNBP1L	476	Q5T0N5
RPLTRGLASAAKGGH	COX6A2	6	Q02221
SSGHAGGPVSARVIK	ENPP3	326	O14638
TDGARTKIGFSEGRH	FBXO45	141	P0C2W1
ESKRKSGGRGSPSSH	LINC02908	171	Q6ZV77
RHQDSSRNKAGGLPG	GGT6	41	Q6P531
HRKAGGTDAPSANGE	DNAJB12	71	Q9NXW2
TAKSGGHIGRAESDP	CEP350	461	Q5VT06
RIAQHGGAEPSGRKQ	CCDC57	721	Q2TAC2
PQDAVGRSHSGLSKG	DNAJC17	251	Q9NVM6
GDRGAPKRGSGKDSH	MBP	181	P02686
ARGHTNGTKPLDGFD	ARSB	361	P15848
ADGLKPRNHFGVGRS	CRYBG1	211	Q9Y4K1
THKAAATGARGPGEL	COL13A1	6	Q5TAT6
GSVAHRTGTLEPGDK	GRIP2	591	Q9C0E4
RDGLSVPKHSAGSGA	C1orf174	136	Q8IYL3
SRHPGQSLLAKAGDG	PRDM13	651	Q9H4Q3
GGGPSSGHRDLSIIK	CCDC24	136	Q8N4L8
AIRHEGKSPGLGTDS	EPB41L3	496	Q9Y2J2
KAGSRGRFAGHSEAG	PAK4	131	O96013
RATAGKSTPGRQAHG	JARID2	501	Q92833
HKASRVSKGGSFGRG	OAS3	451	Q9Y6K5
RSLGEPAAGEGSAKR	RPP25	171	Q9BUL9
RGVSPSKAHGLGSNL	HNF1B	276	P35680
RPGGRRHSKGNPESS	SENP2	161	Q9HC62
VSAQPGAGTGSAKHR	RAB11FIP1	1161	Q6WKZ4
AHGRRGGPEGKSSSR	SRRM3	476	A6NNA2
ARGGSALPGSRNLVH	PSD	161	A5PKW4
FGTRLHGGKDAASPR	TOP2B	811	Q02880
QSHGGPRSLSDIKGA	TRAFD1	271	O14545
PGQAGGHASDTRPTK	TEDC2	126	Q7L2K0
HRKLSNPRGGEGSES	RIMBP3	341	Q9UFD9
RKDSGSPNPARGHSV	MYC	156	P01106
AHARAGEAKGQAPTG	PNMA8B	601	Q9ULN7
GAGASSRSPKQARLG	PRR36	1231	Q9H6K5
KSADEHTGRAGPSVG	SELENOO	261	Q9BVL4
RTGEQGHRSKGPRTS	SPATA31E1	1211	Q6ZUB1
GHRSKGPRTSEASGR	SPATA31E1	1216	Q6ZUB1
DGGSGLGSHRRKRTT	SEBOX	11	Q9HB31
SQGKGAHRPEHASGR	SLC39A6	161	Q13433
GHKTPRRDSSGGTKD	PRKAB1	16	Q9Y478
ITHGSGPGARREAFK	CHST6	306	Q9GZX3
LRVRIASDSGGPHGS	RINL	281	Q6ZS11
GSHRKRCGDLPSGAS	PLEKHG5	951	O94827
NPSRGTDTAKHRGGL	PLEKHA6	666	Q9Y2H5
TDTAKHRGGLGPSAT	PLEKHA6	671	Q9Y2H5
GTLEGSRQGSPGHRK	SHF	16	Q7M4L6
ARAAKLEPSGHVAGG	ZFHX4	1576	Q86UP3
RKLRGNGSGHIGSSV	ZC3H6	786	P61129
GDSHGSGAKLGDPRL	ZC3H6	951	P61129
DKHSQSPRAAGPREG	PBXIP1	706	Q96AQ6
GRLTDQKGRGHPAGS	SPANXA2-OT1	6	Q8N9U9
GKTPGQRSRADAGHA	SPIN1	6	Q9Y657
GKAAAGQRSRTGAGH	SPIN3	6	Q5JUX0
RGAKGERGSKSHPNA	STC2	256	O76061
RKSQARHVGSRGGPS	THSD1	626	Q9NS62
LGDSGGTPVKTRRHS	TBC1D1	646	Q86TI0
LGHLGKSGSGRVRQT	PRPF31	396	Q8WWY3
DSLRKALAGHGGSRQ	NF1	301	P21359
RARLSHGDRGTDGKA	PHF3	1971	Q92576
HGDRGTDGKASRDSR	PHF3	1976	Q92576
TTLEDKGPGHATFGR	PRRC2B	1001	Q5JSZ5
TAPGDGAGASRQRKL	ROCK2	16	O75116
SASNGGGSPARREEK	SORBS3	366	O60504
AKAASQTAGSRGRHG	PRAG1	266	Q86YV5
TRHQKGLGGRAPSGA	ZFP42	11	Q96MM3
HRGKRSAGKAAGSPG	ZNF469	3211	Q96JG9
GTRLHGGKDSASPRY	TOP2A	791	P11388
AAGSHRAGERAKGPS	WRNIP1	51	Q96S55
GPVQSGRGSHAAELR	ZCCHC14	386	Q8WYQ9
APQAHGKGEASGSSR	ZNF205	171	O95201
RRTHAGKSGAPPTGA	ZNF526	406	Q8TF50
AGEGRGAGKHVRSSS	USP31	1186	Q70CQ4
GTRGLAAPGSRDHQK	TMEM41B	26	Q5BJD5
VKGRVKSGSPHTGDR	TMC2	16	Q8TDI7
KSGSPHTGDRLGRRS	TMC2	21	Q8TDI7
VSQGKRKRGCSHPGG	XPC	51	Q01831
HKGPRDLQASSGGNR	SULF1	581	Q8IWU6
LQGSSHGGAVRPRAL	TTC39A	141	Q5SRH9
GHGRTRRKDASKATG	THAP4	96	Q8WY91
RRTGSPGEGAHVSAA	AVPR2	251	P30518
GREKHGASEGPQRSL	VWA5B1	981	Q5TIE3
APGGHSRSKEGQRGR	TMEM108	186	Q6UXF1
GGSSGKGHSRDFVLR	ZIC5	186	Q96T25
RGNHSQGGVARIKPA	N4BP2	1731	Q86UW6
PGGLTASRGRVHEAS	MYOM1	851	P52179