Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentsarcomere

FLNB SORBS2 OBSL1 DNAJB4 PARVB FBP2 RYR1 ACTL8 RPL4 NBR1

3.92e-0624913110GO:0030017
GeneOntologyCellularComponentmyofibril

FLNB SORBS2 OBSL1 DNAJB4 PARVB FBP2 RYR1 ACTL8 RPL4 NBR1

8.82e-0627313110GO:0030016
GeneOntologyCellularComponentcontractile muscle fiber

FLNB SORBS2 OBSL1 DNAJB4 PARVB FBP2 RYR1 ACTL8 RPL4 NBR1

1.49e-0529013110GO:0043292
GeneOntologyCellularComponentsupramolecular fiber

KRT4 FLNB SORBS2 CENPE OBSL1 DNAJB4 PARVB FBP2 KRT79 SHROOM2 RYR1 PPL MISP DNAH12 DPP9 ACTL8 KRT77 POTEJ RPL4 NBR1

4.50e-05117913120GO:0099512
GeneOntologyCellularComponentZ disc

FLNB SORBS2 OBSL1 DNAJB4 PARVB FBP2 RYR1

4.72e-051511317GO:0030018
GeneOntologyCellularComponentsupramolecular polymer

KRT4 FLNB SORBS2 CENPE OBSL1 DNAJB4 PARVB FBP2 KRT79 SHROOM2 RYR1 PPL MISP DNAH12 DPP9 ACTL8 KRT77 POTEJ RPL4 NBR1

4.94e-05118713120GO:0099081
GeneOntologyCellularComponentI band

FLNB SORBS2 OBSL1 DNAJB4 PARVB FBP2 RYR1

8.58e-051661317GO:0031674
GeneOntologyCellularComponentsperm head

DNAJB1 PCDH11Y HSP90AB1

8.63e-04301313GO:0061827
DomainARM-type_fold

IPO8 IPO7 MROH2A INTS1 USP24 HEATR1 USP9Y NCAPG2 MTOR PPP6R2 TNPO3 PPP6R3

4.12e-0633912912IPR016024
DomainCalx_beta

FRAS1 ADGRV1 FREM2

1.76e-0581293SM00237
DomainARM-like

IPO8 IPO7 MROH2A HEATR1 USP9Y NCAPG2 MTOR PPP6R2 TNPO3 PPP6R3

1.83e-0527012910IPR011989
DomainCalx_beta

FRAS1 ADGRV1 FREM2

2.62e-0591293IPR003644
DomainDnaJ_C

DNAJB1 DNAJB4 DNAJB5

2.62e-0591293IPR002939
DomainDnaJ_C

DNAJB1 DNAJB4 DNAJB5

2.62e-0591293PF01556
DomainHSP40/DnaJ_pept-bd

DNAJB1 DNAJB4 DNAJB5

2.62e-0591293IPR008971
DomainCalx-beta

FRAS1 ADGRV1 FREM2

2.62e-0591293PF03160
DomainSAPS

PPP6R2 PPP6R3

1.41e-0431292IPR007587
DomainCse1

IPO8 IPO7

1.41e-0431292PF08506
DomainCse1

IPO8 IPO7

1.41e-0431292IPR013713
DomainSAPS

PPP6R2 PPP6R3

1.41e-0431292PF04499
DomainKeratin_II

KRT4 KRT79 KRT77

7.45e-04261293IPR003054
DomainDnaJ_domain_CS

DNAJB1 DNAJB4 DNAJB5

8.34e-04271293IPR018253
DomainHEAT_REPEAT

MROH2A HEATR1 NCAPG2 MTOR

1.40e-03701294PS50077
DomainSAM_MT_PRMT

PRMT6 PRMT9

1.65e-0391292PS51678
DomainArg_MeTrfase

PRMT6 PRMT9

1.65e-0391292IPR025799
DomainJmjN

KDM5D KDM4B

2.05e-03101292SM00545
DomainJmjN

KDM5D KDM4B

2.05e-03101292PF02375
DomainJMJN

KDM5D KDM4B

2.05e-03101292PS51183
DomainJmjN

KDM5D KDM4B

2.05e-03101292IPR003349
DomainZnF_UBP

BRAP USP33

2.50e-03111292SM00290
DomainGrpE_coiled_coil

KRT4 KRT77

2.99e-03121292IPR013805
DomainAAA

PEX6 ABCA7 MMAA DNAH12 ABCC2

3.26e-031441295SM00382
DomainAAA+_ATPase

PEX6 ABCA7 MMAA DNAH12 ABCC2

3.26e-031441295IPR003593
DomainCarboxyPept_regulatory_dom

CPXM2 CPM

3.51e-03131292IPR014766
Domain-

CPXM2 CPM

3.51e-031312922.60.40.1120
DomainZnf_PHD

ASXL1 KDM5D KMT2A KDM4B

3.65e-03911294IPR001965
DomainZnf_UBP

BRAP USP33

4.08e-03141292IPR001607
DomainIMPORTIN_B_NT

IPO8 IPO7

4.08e-03141292PS50166
Domainzf-UBP

BRAP USP33

4.08e-03141292PF02148
DomainZF_UBP

BRAP USP33

4.08e-03141292PS50271
DomainZF_PHD_2

ASXL1 KDM5D KMT2A KDM4B

4.26e-03951294PS50016
DomainZF_PHD_1

ASXL1 KDM5D KMT2A KDM4B

4.42e-03961294PS01359
DomainDnaJ

DNAJB1 DNAJB4 DNAJB5

4.44e-03481293PF00226
Domain-

IPO8 IPO7 HEATR1 NCAPG2 MTOR TNPO3

4.46e-0322212961.25.10.10
DomainIBN_N

IPO8 IPO7

4.69e-03151292PF03810
DomainDNAJ_1

DNAJB1 DNAJB4 DNAJB5

4.70e-03491293PS00636
DomainDNAJ_2

DNAJB1 DNAJB4 DNAJB5

4.70e-03491293PS50076
DomainDnaJ

DNAJB1 DNAJB4 DNAJB5

4.70e-03491293SM00271
Domain-

DNAJB1 DNAJB4 DNAJB5

4.70e-034912931.10.287.110
DomainDnaJ_domain

DNAJB1 DNAJB4 DNAJB5

5.26e-03511293IPR001623
DomainIBN_N

IPO8 IPO7

5.33e-03161292SM00913
DomainMMR_HSR1

GTPBP10 ERAL1

6.02e-03171292PF01926
DomainCarboxyPept-like_regulatory

CPXM2 CPM

6.02e-03171292IPR008969
DomainImportin-beta_N

IPO8 IPO7

6.02e-03171292IPR001494
DomainZn_pept

CPXM2 CPM

6.74e-03181292SM00631
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

DNAJB1 FLNB IPO8 IPO7 OBSL1 FARSB BRCC3 HEATR1 NCAPG2 PPL HNRNPUL2 MTOR ERAL1 PGLS PRMT9 FUT8 ESPL1 PPP6R2 RPL4 TNPO3 PRRC2B PPP6R3 VCPIP1

2.11e-129741312328675297
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

DNAJB1 MIA3 IPO7 IARS1 USP24 OBSL1 FARSB QRICH1 HEATR1 NCAPG2 PDE12 MTOR FUT8 ESPL1 NBR1 TNPO3 PPP6R3 VCPIP1 HDLBP HSP90AB1

4.30e-109421312031073040
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

DNAJB1 FRAS1 MIA3 IPO8 IPO7 MINK1 OBSL1 DNAJB4 HEATR1 NCAPG2 BRAP MPRIP PDE12 DPP9 ERAL1 AKAP11 DNAJB5 ESPL1 PPP6R2 RPL4 NBR1 USP33 PPP6R3 HDLBP

1.59e-0914871312433957083
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

DNAJB1 FLNB IPO8 ACACA IPO7 IARS1 USP24 DNAJB4 HEATR1 MTOR ERAL1 DNAJB5 RPL4 TNPO3 PPP6R3 HSP90AB1

2.69e-096381311633239621
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

DNAJB1 KRT4 FLNB ACACA IPO7 IARS1 USP24 POLR2J FARSB DNAJB4 SRGAP2 KRT79 BIRC6 GTPBP10 ACTL8 PGLS RPL4 NBR1 PPP6R3 VCPIP1 DNPEP HDLBP HSP90AB1

3.20e-0914151312328515276
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

DNAJB1 FLNB ACACA IPO7 IARS1 USP24 FARSB DNAJB4 BRCC3 QRICH1 BIRC6 PRMT6 PDE12 DPP9 HNRNPUL2 MTOR TNPO3 PPP6R3 VCPIP1 DNPEP HDLBP HSP90AB1

2.67e-0814551312222863883
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

FLNB SORBS2 OBSL1 BRCC3 PARVB SRGAP2 QRICH1 USP9Y SHROOM2 SH2B1 MPRIP ZNF18 OTOF CIAO2B CHD6 FUT8 CNOT3 USP33 VCPIP1 HSP90AB1

7.78e-0812851312035914814
Pubmed

DDX39B facilitates the malignant progression of hepatocellular carcinoma via activation of SREBP1-mediated de novo lipid synthesis.

IPO7 SREBF1 MPRIP MISP RPL4 HSP90AB1

1.45e-0763131637052853
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

ASXL1 IARS1 OBSL1 ID3 FARSB QRICH1 HEATR1 CBFA2T3 SH2B1 NFATC2 HNRNPUL2 ERAL1 BANP SMARCB1 NBR1 HSP90AB1

1.59e-078571311625609649
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FRAS1 ACACA KSR2 INTS1 SREBF1 PEX6 PARVB SRGAP2 BIRC6 ABCA7 RYR1 MPRIP PER2 MTOR BANP ESPL1 TNPO3 PRRC2B

1.91e-0711051311835748872
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

MIA3 IPO8 CENPE OBSL1 PEX6 HEATR1 BIRC6 GTPBP10 PDE12 HNRNPUL2 ERAL1 KRT77 PTAR1 AKAP11 ESPL1 RPL4 NBR1 PGBD5 PRRC2B USP33 VCPIP1

1.99e-0714961312132877691
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

DNAJB1 KRT4 FLNB ASXL1 EDC3 IPO7 IARS1 BRCC3 KRT79 PDE12 KRT77 PPP6R2 TNPO3 PRRC2B USP33 PPP6R3 VCPIP1

2.55e-0710051311719615732
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

CENPE TOPBP1 OBSL1 BRAP MPRIP BANP POTEJ PPP6R2 CNOT3 PRRC2B PPP6R3 VCPIP1 HDLBP

3.81e-075881311338580884
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

FLNB MIA3 ACACA IPO7 IARS1 USP24 FARSB DNAJB4 BIRC6 MISP SMARCB1 RPL4 NBR1 TNPO3 CNOT3 PRRC2B PPP6R3 DNPEP HSP90AB1

4.27e-0712971311933545068
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

DNAJB1 FLNB EDC3 IPO7 INTS1 USP24 HEATR1 PDE12 SMARCB1 TNPO3 PPP6R3 HDLBP

4.43e-074981311236634849
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ASXL1 FRAS1 SORBS2 OBSL1 EPG5 PER2 ACOT11 CHD6 PRRC2B USP33 VCPIP1

4.45e-074071311112693553
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

DNAJB1 EDC3 ACACA FARSB SRGAP2 HEATR1 BRAP MPRIP KMT2A PPP6R2 RPL4 PRRC2B PPP6R3 VCPIP1 HDLBP HSP90AB1

5.00e-079341311633916271
Pubmed

Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.

EDC3 IPO8 ACACA IPO7 TOPBP1 FARSB RPL4 PRRC2B HDLBP HSP90AB1

1.10e-063571311037059091
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

FRAS1 MIA3 MINK1 SREBF1 OBSL1 PEX6 NCAPG2 FREM2 HNRNPUL2 KMT2A PPP6R2 PRRC2B USP33

1.17e-066501311338777146
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

FLNB ACACA IPO7 INTS1 USP24 HEATR1 BIRC6 MTOR KMT2A RPL4 PRRC2B PPP6R3 HDLBP

1.23e-066531311322586326
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

MIA3 EDC3 ACACA MISP AKAP11 NBR1 PPP6R3 VCPIP1

1.37e-06209131836779422
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

MIA3 ACACA USP24 FARSB PHKA1 PDE12 ERAL1 PPP6R2

1.52e-06212131833853758
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

DNAJB1 ASXL1 EDC3 IPO8 CENPE TOPBP1 DNAJB4 CPM PPL MPRIP MISP PER2 HNRNPUL2 SMARCB1 ESPL1 CNOT3 PRRC2B

1.72e-0611551311720360068
Pubmed

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway.

OBSL1 DNAJB4 HEATR1 KRT79 OGN NCAPG2 FREM2 NBR1 CNOT3

2.33e-06302131930561431
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

FLNB MIA3 ACACA IARS1 KRT79 RYR1 EPG5 KRT77 PGLS KMT2A RPL4 DNPEP HDLBP HSP90AB1

2.35e-068071311430575818
Pubmed

Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

OBSL1 ADGRV1 ACOT11 AKAP11 PPP6R2 CNOT3

2.55e-0610213169734811
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

ACACA INTS1 OBSL1 AKAP11 ESPL1 NBR1 PRRC2B VCPIP1

4.06e-06242131834011540
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

DNAJB1 SORBS2 EDC3 ACACA MINK1 BRCC3 SRGAP2 MPRIP MTOR KRT77 KMT2A AKAP11 TNPO3 VCPIP1

4.93e-068611311436931259
Pubmed

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.

ACACA OBSL1 PARVB HEATR1 USP9Y PHKA1 KMT2A AKAP11 PPP6R3 HSP90AB1

5.97e-064321311023455922
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

FLNB MIA3 SORBS2 ACACA IARS1 MINK1 USP24 PALMD SHROOM2 BIRC6 HNRNPUL2 PPP6R2 CNOT3 VCPIP1 HDLBP HSP90AB1

6.41e-0611391311636417873
Pubmed

Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.

IPO8 IPO7 IARS1 NCAPG2 MTOR TNPO3 HSP90AB1

6.41e-06183131723956138
Pubmed

14-3-3-affinity purification of over 200 human phosphoproteins reveals new links to regulation of cellular metabolism, proliferation and trafficking.

FLNB EDC3 ACACA SRGAP2 MPRIP PGLS DNPEP

7.13e-06186131714744259
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

FLNB SORBS2 IARS1 MINK1 FARSB SRGAP2 KRT79 SHROOM2 MPRIP MISP HNRNPUL2 KMT2A PPP6R2 RPL4 PRRC2B DNPEP HDLBP HSP90AB1

7.42e-0614311311837142655
Pubmed

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.

DNAJB1 IPO8 IPO7 IARS1 DNAJB4 HEATR1 BIRC6 MTOR CIAO2B TNPO3 PPP6R3 HSP90AB1

7.68e-066571311236180527
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

SORBS2 ACACA MINK1 USP24 PPL KMT2A ESPL1 CNOT3 KDM4B PPP6R3 VCPIP1 HDLBP HSP90AB1

7.76e-067741311315302935
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

DNAJB1 ACACA USP24 HEATR1 BRAP MPRIP KMT2A PRRC2B PPP6R3 VCPIP1 HDLBP

7.91e-065491311138280479
Pubmed

Charting the molecular network of the drug target Bcr-Abl.

KRT4 ACACA IARS1 BRCC3 USP9Y KRT79 KRT77 HSP90AB1

8.10e-06266131819380743
Pubmed

Defining the membrane proteome of NK cells.

MIA3 EDC3 IPO7 CENPE IARS1 INTS1 FARSB HEATR1 BIRC6 NCAPG2 HNRNPUL2 MTOR FUT8 RPL4 NBR1 HSP90AB1

8.76e-0611681311619946888
Pubmed

Disruption of the AMPK-TBC1D1 nexus increases lipogenic gene expression and causes obesity in mice via promoting IGF1 secretion.

ACACA SREBF1 MTOR

1.12e-0512131327307439
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

DNAJB1 IPO8 IPO7 IARS1 FARSB BRCC3 HMCN2 ERAL1 CIAO2B SMARCB1 PPP6R2 RPL4 TNPO3 PPP6R3 DNPEP HDLBP HSP90AB1

1.16e-0513351311729229926
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

IARS1 HEATR1 KRT79 KRT77 KMT2A POTEJ HDLBP

1.22e-05202131724639526
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

IPO7 INTS1 USP24 SMARCB1 AKAP11 CHD6 TNPO3 CNOT3

1.24e-05282131823667531
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

FLNB MIA3 ACACA MINK1 PCDH11Y KSR2 PARVB SRGAP2 ADGRV1 SHROOM2 SFMBT2 SH2B1 HPS3 DPP9 BANP CHD6 NBR1 KDM4B

1.27e-0514891311828611215
Pubmed

The co-expression of ERβ2 and IL-12Rβ2 is better prognostic factor in non-small-cell lung cancer progression.

IL12RB2 ESR2

1.41e-052131223677568
Pubmed

RNF13, a RING finger protein, mediates endoplasmic reticulum stress-induced apoptosis through the inositol-requiring enzyme (IRE1α)/c-Jun NH2-terminal kinase pathway.

ERN1 RNF13

1.41e-052131223378536
Pubmed

Identification of two novel CAKUT-causing genes by massively parallel exon resequencing of candidate genes in patients with unilateral renal agenesis.

FRAS1 FREM2

1.41e-052131221900877
Pubmed

Molecular study of 33 families with Fraser syndrome new data and mutation review.

FRAS1 FREM2

1.41e-052131218671281
Pubmed

Circadian Period 2 (Per2) downregulate inhibitor of differentiation 3 (Id3) expression via PTEN/AKT/Smad5 axis to inhibits glioma cell proliferation.

ID3 PER2

1.41e-052131235599595
Pubmed

Novel loss of function variants in FRAS1 AND FREM2 underlie renal agenesis in consanguineous families.

FRAS1 FREM2

1.41e-052131232643034
Pubmed

Hsc40, a new member of the hsp40 family, exhibits similar expression profile to that of hsc70 in mammalian cells.

DNAJB1 DNAJB5

1.41e-052131210570961
Pubmed

Nonalcoholic fatty liver disease impairs the cytochrome P-450-dependent metabolism of α-tocopherol (vitamin E).

SREBF1 CYP4F2

1.41e-052131228628909
Pubmed

Prostaglandin F2alpha promotes muscle cell survival and growth through upregulation of the inhibitor of apoptosis protein BRUCE.

BIRC6 NFATC2

1.41e-052131218566603
Pubmed

mTOR signaling regulates central and peripheral circadian clock function.

PER2 MTOR

1.41e-052131229750810
Pubmed

Regulation of SREBP1c expression by mTOR signaling in hepatocytes.

SREBF1 MTOR

1.41e-052131220847591
Pubmed

Insulin-induced de novo lipid synthesis occurs mainly via mTOR-dependent regulation of proteostasis of SREBP-1c.

SREBF1 MTOR

1.41e-052131231541353
Pubmed

Fyn Activation of mTORC1 Stimulates the IRE1α-JNK Pathway, Leading to Cell Death.

ERN1 MTOR

1.41e-052131226306048
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

DNAJB1 FLNB EDC3 IPO7 IARS1 MINK1 USP24 FARSB RPL4 VCPIP1 HDLBP HSP90AB1

1.61e-057081311239231216
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

MIA3 EDC3 CENPE SRGAP2 BIRC6 BRAP BANP CHD6 ESPL1 NBR1 USP33 VCPIP1

2.27e-057331311234672954
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

FLNB EDC3 ACACA CENPE IARS1 INTS1 BIRC6 RYR1 FREM2 PDE12 CHD6 HSP90AB1

2.36e-057361311229676528
Pubmed

Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta.

ASXL1 IMPACT KMT2A AKAP11 PRRC2B

2.39e-0590131515033168
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

ASXL1 OBSL1 ADGRV1 BIRC6 AKAP11 CHD6 KDM4B

2.44e-05225131712168954
Pubmed

mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.

IARS1 FARSB MPRIP MTOR KRT77 RPL4 HDLBP HSP90AB1

2.55e-05312131837120454
Pubmed

The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.

IL12RB2 ERN1 CENPE NCAPG2 NFATC2 MTOR ESPL1

2.59e-05227131726410627
Pubmed

Isoform-specific GSK3A activity is negatively correlated with human sperm motility.

DNAJB1 AKAP11 NBR1 VCPIP1 HSP90AB1

2.66e-0592131530824926
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

DNAJB1 FLNB IPO8 ACACA IPO7 IARS1 FARSB HEATR1 PDE12 HNRNPUL2 MTOR ERAL1 RPL4 NBR1 DNPEP HDLBP HSP90AB1

2.67e-0514251311730948266
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

IPO8 ACACA IPO7 NUP210L IARS1 SREBF1 DNAJB4 HEATR1 MISP ERAL1 CHD6 HDLBP

2.98e-057541311235906200
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

DNAJB1 FLNB IPO8 IPO7 FARSB HEATR1 GTPBP10 NCAPG2 HNRNPUL2 MTOR ERAL1 CIAO2B KMT2A TNPO3 CNOT3 PRRC2B PPP6R3

3.04e-0514401311730833792
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

DNAJB1 FLNB MINK1 CDHR5 FBP2 ADGRV1 PKD1L3 SHROOM2 RYR1 PPL ACOT11 CAPN7 PGLS MMRN2

3.11e-0510161311419056867
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

FLNB CENPE MINK1 MPRIP OTOF TNPO3 HSP90AB1

3.14e-05234131736243803
Pubmed

LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.

IARS1 OBSL1 SRGAP2 PHKA1 HNRNPUL2 CIAO2B KMT2A PPP6R2 RPL4 PPP6R3 HSP90AB1

3.20e-056391311123443559
Pubmed

A Cas9 Ribonucleoprotein Platform for Functional Genetic Studies of HIV-Host Interactions in Primary Human T Cells.

CIAO2B SMARCB1 TNPO3

3.42e-0517131327783955
Pubmed

Cyclophilin D deficiency attenuates mitochondrial perturbation and ameliorates hepatic steatosis.

ERN1 SREBF1

4.21e-053131229356058
Pubmed

Identification of genes for normalization of quantitative real-time PCR data in ovarian tissues.

RPL4 HSP90AB1

4.21e-053131220705598
Pubmed

Leukemic HRX fusion proteins inhibit GADD34-induced apoptosis and associate with the GADD34 and hSNF5/INI1 proteins.

SMARCB1 KMT2A

4.21e-053131210490642
Pubmed

[Research on the mechanism of hypoxia promoting the migration of lung adenocarcinoma A549 cells].

ACACA SREBF1

4.21e-053131235634673
Pubmed

Cell fate determinant Llgl1 is required for propagation of acute myeloid leukemia.

MTOR KMT2A

4.21e-053131237587260
Pubmed

SREBP1-Induced Glutamine Synthetase Triggers a Feedforward Loop to Upregulate SREBP1 through Sp1 O-GlcNAcylation and Augments Lipid Droplet Formation in Cancer Cells.

ACACA SREBF1

4.21e-053131234575972
Pubmed

Chrysophanol inhibits the osteoglycin/mTOR and activats NF2 signaling pathways to reduce viability and proliferation of malignant meningioma cells.

OGN MTOR

4.21e-053131233622177
Pubmed

TANGO1 interacts with NRTN to promote hepatocellular carcinoma progression by regulating the PI3K/AKT/mTOR signaling pathway.

MIA3 MTOR

4.21e-053131237211171
Pubmed

Estrogen receptor alpha and beta regulate actin polymerization and spatial memory through an SRC-1/mTORC2-dependent pathway in the hippocampus of female mice.

ESR2 MTOR

4.21e-053131228789972
Pubmed

SREBF1 Activity Is Regulated by an AR/mTOR Nuclear Axis in Prostate Cancer.

SREBF1 MTOR

4.21e-053131229784665
Pubmed

Estrogen activates the high-density lipoprotein receptor gene via binding to estrogen response elements and interaction with sterol regulatory element binding protein-1A.

ESR2 SREBF1

4.21e-053131212021179
Pubmed

mTOR Driven Gene Transcription Is Required for Cholesterol Production in Neurons of the Developing Cerebral Cortex.

SREBF1 MTOR

4.21e-053131234204880
Pubmed

mTOR signaling in VIP neurons regulates circadian clock synchrony and olfaction.

PER2 MTOR

4.21e-053131229555746
Pubmed

Involvement of DPP9 in gene fusions in serous ovarian carcinoma.

DPP9 PPP6R3

4.21e-053131228893231
Pubmed

Preferential utilization of Imp7/8 in nuclear import of Smads.

IPO8 IPO7

4.21e-053131218519565
Pubmed

Estrogen receptorβ2 regulates interlukin-12 receptorβ2 expression via p38 mitogen-activated protein kinase signaling and inhibits non-small-cell lung cancer proliferation and invasion.

IL12RB2 ESR2

4.21e-053131225695486
Pubmed

CircBIRC6 affects prostate cancer progression by regulating miR-574-5p and DNAJB1.

DNAJB1 BIRC6

4.21e-053131239258752
Pubmed

mTOR direct crosstalk with STAT5 promotes de novo lipid synthesis and induces hepatocellular carcinoma.

SREBF1 MTOR

4.21e-053131231409773
Pubmed

Expression of Fraser syndrome genes in normal and polycystic murine kidneys.

FRAS1 FREM2

4.21e-053131221993971
Pubmed

14-3-3 epsilon dynamically interacts with key components of mitogen-activated protein kinase signal module for selective modulation of the TNF-alpha-induced time course-dependent NF-kappaB activity.

IPO8 ADH4 RPL4 HSP90AB1

4.52e-0552131420462248
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

IPO8 ACACA ERN1 CRPPA HEATR1 RYR1 FREM2 NFATC2 AKAP11 KDM4B

4.85e-055521311010737800
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

MIA3 EDC3 BIRC6 BRAP PHKA1 AKAP11 PRRC2B

4.89e-05251131729778605
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

DNAJB1 EDC3 MINK1 INTS1 TOPBP1 FARSB SRGAP2 HEATR1 GTPBP10 MPRIP NFATC2 KMT2A CHD6 FUT8 CNOT3 PPP6R3 HDLBP

4.93e-0514971311731527615
Pubmed

RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.

ACACA IPO7 IARS1 USP24 CIAO2B KMT2A RPL4 HSP90AB1

5.09e-05344131836282215
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

FLNB IPO7 HEATR1 MISP NBR1 VCPIP1 HDLBP

5.54e-05256131733397691
Pubmed

The scaffold protein KSR1, a novel therapeutic target for the treatment of Merlin-deficient tumors.

DNAJB1 IPO7 DNAJB4 RPL4 PPP6R3 DNPEP HDLBP HSP90AB1

5.74e-05350131826549023
Pubmed

Progesterone induced Warburg effect in HEK293 cells is associated with post-translational modifications and proteasomal degradation of progesterone receptor membrane component 1.

USP24 MPRIP MTOR PPP6R3

6.97e-0558131431067491
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

KRT4 FLNB MIA3 SORBS2 IARS1 SRGAP2 PPL MMRN2

6.99e-05360131833111431
Pubmed

Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.

USP24 SRGAP2 GTPBP10 PDE12 MTOR AKAP11

7.09e-05183131631932471
InteractionCOMTD1 interactions

IPO8 IPO7 IARS1 INTS1 HEATR1 NCAPG2 PHKA1 MTOR CIAO2B PRMT9 TNPO3

7.85e-0820013111int:COMTD1
InteractionNPAS1 interactions

INTS1 PEX6 DNAJB4 QRICH1 MISP AKAP11 DNAJB5 PPP6R2 VCPIP1 HDLBP HSP90AB1

6.02e-0724513111int:NPAS1
InteractionPIH1D1 interactions

KRT4 FLNB ACACA IPO7 IARS1 KSR2 USP24 POLR2J BIRC6 MISP ACTL8 MTOR PGLS KMT2A RPL4 DNPEP HDLBP HSP90AB1

1.23e-0673113118int:PIH1D1
InteractionLMBR1L interactions

DNAJB1 MIA3 IPO7 IARS1 USP24 OBSL1 FARSB QRICH1 HEATR1 NCAPG2 PDE12 MTOR FUT8 ESPL1 NBR1 TNPO3 PPP6R3 VCPIP1 HDLBP HSP90AB1

3.11e-0694613120int:LMBR1L
InteractionYWHAE interactions

SORBS2 EDC3 IPO8 CENPE ESR2 MINK1 KSR2 OBSL1 SRGAP2 SHROOM2 MPRIP ADH4 PER2 NFATC2 MTOR CAPN7 KRT77 KMT2A AKAP11 RPL4 NBR1 HDLBP HSP90AB1

5.80e-06125613123int:YWHAE
InteractionASPM interactions

IPO7 CENPE NCAPG2 PER2 MTOR DNAJB5 ESPL1 PPP6R2

1.20e-051641318int:ASPM
InteractionFAM174A interactions

IPO8 IPO7 INTS1 PEX6 HEATR1 NCAPG2 MTOR FUT8 TNPO3

1.61e-052241319int:FAM174A
InteractionHPSE2 interactions

FRAS1 PEX6 RNF13 ADGRV1

1.94e-05251314int:HPSE2
InteractionPRTN3 interactions

FRAS1 MIA3 ESR2 OBSL1 QRICH1 BIRC6

2.85e-05911316int:PRTN3
InteractionCLEC11A interactions

POLR2J PEX6 RNF13 BIRC6 MISP PRRC2B

3.86e-05961316int:CLEC11A
InteractionSFN interactions

DNAJB1 SORBS2 EDC3 ESR2 MINK1 SRGAP2 MPRIP CDCA7 MTOR KRT77 BANP KMT2A AKAP11 RPL4 VCPIP1

4.46e-0569213115int:SFN
InteractionKIF20A interactions

FLNB CENPE NUP210L IARS1 ESR2 MINK1 HEATR1 CPM USP9Y PPL MPRIP MISP HNRNPUL2 FER1L4 SMARCB1 POTEJ RPL4 PRRC2B HSP90AB1

5.01e-05105213119int:KIF20A
InteractionYWHAG interactions

DNAJB1 SORBS2 EDC3 ESR2 MINK1 KSR2 USP24 BRCC3 SRGAP2 SHROOM2 MPRIP NFATC2 CDCA7 MTOR KRT77 KMT2A AKAP11 NBR1 TNPO3 PPP6R3 HSP90AB1

5.41e-05124813121int:YWHAG
InteractionBRCA1 interactions

DNAJB1 FLNB ACACA IPO7 IARS1 ESR2 POLR2J TOPBP1 FARSB BRCC3 NCAPG2 SH2B1 BRAP PDE12 HNRNPUL2 MTOR SMARCB1 RPL4 PPP6R3 HDLBP HSP90AB1

5.47e-05124913121int:BRCA1
InteractionEFTUD2 interactions

DNAJB1 FLNB ASXL1 ACACA IPO7 IARS1 USP24 OBSL1 FARSB DNAJB4 SRGAP2 BIRC6 GTPBP10 ACTL8 PGLS SMARCB1 RPL4 NBR1 PPP6R3 VCPIP1 DNPEP HDLBP HSP90AB1

5.62e-05144913123int:EFTUD2
InteractionDNAJB7 interactions

DNAJB1 IPO8 IPO7 RPL4

6.80e-05341314int:DNAJB7
InteractionBTNL9 interactions

IPO8 IPO7 MROH2A INTS1 EPG5 PRMT9 TNPO3

7.28e-051561317int:BTNL9
InteractionKRT25 interactions

KRT4 KRT79 PPL KRT77

7.64e-05351314int:KRT25
InteractionMLNR interactions

IPO8 IPO7 INTS1 HEATR1 TNPO3

8.07e-05681315int:MLNR
InteractionTANK interactions

ESR2 OBSL1 DNAJB4 HEATR1 KRT79 OGN NCAPG2 CNOT3

8.56e-052161318int:TANK
InteractionDKKL1 interactions

FRAS1 PEX6 ADGRV1 FREM2 PRMT9 FUT8

8.71e-051111316int:DKKL1
InteractionLENG8 interactions

MIA3 ESR2 PRMT6 PER2 SMARCB1 RPL4 HDLBP

9.96e-051641317int:LENG8
InteractionMPPED1 interactions

PHKA1 CIAO2B USP33 DNPEP

1.18e-04391314int:MPPED1
InteractionSLC9C1 interactions

OBSL1 SLC9C1

1.25e-0431312int:SLC9C1
InteractionNLRP8 interactions

DNAJB4 DNAJB5

1.25e-0431312int:NLRP8
InteractionTASP1 interactions

KMT2A HDLBP HSP90AB1

1.41e-04161313int:TASP1
InteractionKCNA3 interactions

DNAJB1 FLNB EDC3 IPO7 IARS1 MINK1 USP24 FARSB RYR1 PPL MPRIP KMT2A RPL4 VCPIP1 HDLBP HSP90AB1

1.71e-0487113116int:KCNA3
InteractionCASZ1 interactions

ESR2 BIRC6 SFMBT2 RPL4

1.73e-04431314int:CASZ1
InteractionLOC254896 interactions

EDC3 ADGRV1 FREM2 BANP

1.73e-04431314int:LOC254896
InteractionILVBL interactions

INTS1 HEATR1 NCAPG2 MTOR CIAO2B PPP6R2 TNPO3

1.97e-041831317int:ILVBL
Cytoband3p14.3

FLNB PDE12 DNAH12

8.71e-053013133p14.3
GeneFamilyArmadillo repeat containing|Importins

IPO8 IPO7 TNPO3

1.19e-0418983596
GeneFamilyKeratins, type II

KRT4 KRT79 KRT77

4.11e-0427983609
GeneFamilyFerlin family

OTOF FER1L4

4.30e-046982828
GeneFamilyProtein phosphatase 6 regulatory subunits

PPP6R2 PPP6R3

4.30e-046982699
GeneFamilyProtein arginine methyltransferases

PRMT6 PRMT9

1.02e-039982691
GeneFamilyDNAJ (HSP40) heat shock proteins|C2 tensin-type domain containing

DNAJB1 DNAJB4 DNAJB5

2.37e-0349983584
GeneFamilyEndogenous ligands|Minor histocompatibility antigens

HEATR1 KDM5D USP9Y

2.66e-0351983870
GeneFamilyUbiquitin specific peptidases

USP24 USP9Y USP33

3.48e-0356983366
CoexpressionBENPORATH_CYCLING_GENES

DNAJB1 ASXL1 CENPE TOPBP1 DNAJB4 QRICH1 ABCA7 ADH4 CDCA7 CAPN7 SMARCB1 ABCC2 ESPL1 PPP6R3

4.75e-0664813114M8156
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FRAS1 ADAM7 ADGRV1 USP9Y SFMBT2 FREM2 ABCC2

5.29e-071621317bf886e22ff2a20353499004b53f25fb9e6574896
ToppCelldroplet-Lung-nan-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT4 SORBS2 RAMP3 PARVB PALMD MMRN2 TPBG

1.38e-06187131764dd28b23eda7dfb7fd069be2742de7bad0fd87a
ToppCellLV-10._Endothelium_II|World / Chamber and Cluster_Paper

FLNB RAMP3 CPXM2 PCDH11Y ID3 SHROOM2 MMRN2

1.38e-0618713177876dcb4800c2e54874df3d933efb79307a64a97
ToppCelldroplet-Lung-nan-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT4 SORBS2 RAMP3 PARVB PALMD MMRN2 TPBG

1.38e-061871317b535d5447bf15e95dcf025a0a455628b956fc857
ToppCellE17.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FLNB SORBS2 ID3 PARVB PALMD CBFA2T3 MMRN2

1.43e-06188131759f276e23c8380bae57d7ecca3a8b83df4bc150b
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNB SORBS2 ID3 PARVB PALMD CBFA2T3 MMRN2

1.59e-06191131727f23c2254b610abac1a88d0fecff305addde9da
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SORBS2 PCDHGC5 KSR2 CRPPA BRAP ADH4 DNAH12

1.71e-061931317088c8b1e968f5356502347eaabdc6b1b1d4befd0
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAJB1 RAMP3 ID3 DNAJB4 PALMD MMRN2 HSP90AB1

1.83e-0619513175a8b26f443684f9f194cc85a4a390144b7242403
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 ADGRV1 USP9Y FREM2 SLC9C1 ABCC2

4.53e-06145131696712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RAMP3 CENPE NUP210L PALMD MMRN2 ESPL1

1.46e-051781316ea10117026021c959ffc871fc377cdb3e161d264
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

NUP210L NCAPG2 DNAH12 HMCN2 CDCA7 ESPL1

1.51e-051791316e67ad7ab04d0c1309296f57c1f53c5ca14c213fe
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNB ESR2 ID3 PARVB PALMD MMRN2

1.71e-0518313163427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

SORBS2 ACACA CPM ADGRV1 FREM2 SLC9C1

1.71e-0518313166847c1252d6bb105524f812658112517fd351eab
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SORBS2 ESR2 ID3 PALMD CBFA2T3 MMRN2

1.71e-051831316fc9a7ba148c22d0c8a46f6bc56c772929ac496f7
ToppCellEndothelial-E|World / shred on cell class and cell subclass (v4)

FLNB SORBS2 ID3 PALMD CBFA2T3 MMRN2

1.76e-051841316b4c561924c508536fd2112e91e32176b95fdf63a
ToppCelldroplet-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KRT4 SORBS2 RAMP3 PARVB PALMD MMRN2

1.93e-0518713163827fa80e558b642f3e0036f5ee1a8b69f437e30
ToppCelldroplet-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KRT4 SORBS2 RAMP3 PARVB PALMD MMRN2

1.93e-0518713161bf696eb03422ea507d3efe58dda1d442a65225d
ToppCelldroplet-Lung-3m-Endothelial-venous_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KRT4 SORBS2 RAMP3 PARVB PALMD MMRN2

1.93e-051871316ebe4d1216cc0d4c079b413d5a5460cfd3a4af922
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SORBS2 KSR2 CPM ADGRV1 PHKA1 FREM2

1.93e-051871316db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCellP03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FLNB SORBS2 ESR2 ID3 PARVB MMRN2

1.93e-05187131666ebe1788d51b3e17bec6cdb219f709756b4e530
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CENPE NCAPG2 SFMBT2 RYR1 NFATC2 ESPL1

1.93e-05187131673931a5ea73799095daff100b5f18853c57c74dc
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNB SORBS2 ID3 PALMD CBFA2T3 MMRN2

2.05e-051891316d17e8467699c7ca7694a313c26111f085df5204e
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNB SORBS2 ESR2 ID3 PALMD MMRN2

2.05e-0518913169da012fdfa9a8d488cab710a463a1d70e89f990c
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

USP24 SRGAP2 CBFA2T3 MPRIP PER2 KDM4B

2.11e-051901316ed100e271aac82806f59e0c613ccda63f59100c1
ToppCellwk_08-11-Epithelial-Proximal_epithelial-intermediate_neuroendocrine|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

FLNB KSR2 FAM135B PPL GCNT7 POTEJ

2.11e-0519013165f1863bce9400b7c932f0e4d0e012ec4e8d7e555
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NUP210L ID3 DNAJB4 PALMD SLC9C1 MMRN2

2.11e-051901316d0297d678498e346e56cf95fe9e3db7d3ad3b837
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SORBS2 ID3 PARVB PALMD CBFA2T3 MMRN2

2.18e-0519113160e8a73f01e3ec95d242c09231bcf3790324d0a67
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNB SORBS2 ESR2 ID3 PALMD MMRN2

2.18e-0519113163307dbccadb09c62b0e1c0235ec89bb294d748c3
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SORBS2 ID3 PARVB PALMD CBFA2T3 MMRN2

2.18e-05191131654bbccc554f43ba2ebdf9ea191b94c8f16081b53
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CPXM2 CPM PALMD ADGRV1 FREM2 TPBG

2.18e-05191131663aa671837b79d2feb7ed1e67712cc01caf72bef
ToppCellP07-Endothelial-large_vessel_endothelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ESR2 ID3 PARVB PALMD CBFA2T3 MMRN2

2.18e-051911316d162917816dd2e4767c97447c1cddae9397713ab
ToppCelldroplet-Lung-1m-Endothelial-venous_endothelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNB SORBS2 ID3 PARVB PALMD MMRN2

2.24e-0519213161990dc8a81594018a5bf596be99d0b5f0af0f58f
ToppCellfacs-Kidney-nan-18m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAMP3 ID3 PARVB PALMD CBFA2T3 MMRN2

2.24e-051921316777e386a17bba9ec450bb9d64d8a9ab98d9a63ff
ToppCellfacs-Kidney-nan-18m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAMP3 ID3 PARVB PALMD CBFA2T3 MMRN2

2.24e-05192131660a2409546525a40a5658e0f9d6a50c37f28bb96
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DNAJB1 ASXL1 ID3 DNAJB4 PER2 HSP90AB1

2.24e-0519213166bba80887d6f64cf913a5c22f62baaddda417ce0
ToppCelldroplet-Lung-1m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNB SORBS2 ID3 PARVB PALMD MMRN2

2.24e-051921316845cc9c18b4436b07dd3ce7980052683937546d2
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FRAS1 KSR2 CPM ADGRV1 PPL FREM2

2.24e-051921316b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCellfacs-Kidney-nan-18m-Endothelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAMP3 ID3 PARVB PALMD CBFA2T3 MMRN2

2.24e-0519213160f9db6091b373334b9beabe0e5782bf2bc54690b
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CPM PALMD ADGRV1 PPL FREM2 MISP

2.24e-051921316450baeb5c3df7a9445472530002ce38f177a333c
ToppCelldroplet-Lung-1m-Endothelial-venous_endothelial-vein_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNB SORBS2 ID3 PARVB PALMD MMRN2

2.24e-051921316c72a082c93a8825adbfef37f889ba3a7052f201b
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DNAJB1 ASXL1 DNAJB4 PER2 NFATC2 HSP90AB1

2.31e-051931316dbf0fe496254320c894568c31e5f9ce63707d1b5
ToppCellhuman_hepatoblastoma-Tumor_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

FLNB ASXL1 FRAS1 SORBS2 CHD6 ABCC2

2.31e-051931316503a979328c68b096680b71359a26f02fafdff35
ToppCellLV-10._Endothelium_II|LV / Chamber and Cluster_Paper

FLNB CPXM2 PCDH11Y ID3 SHROOM2 MMRN2

2.38e-051941316b6cc849fa08599bff9839ef382d190cc964e273e
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPXM2 ESR2 PARVB PALMD SFMBT2 MMRN2

2.38e-051941316a429d22c8c9d0fd3bfa9f877a6364cecad68db30
ToppCellPCW_13-14-Epithelial-Epithelial_airway|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CPXM2 CPM ADGRV1 PPL FREM2 MISP

2.38e-0519413167b2b40a56eb9c7203ca50133b2da4fd8fdd4a5cf
ToppCellPCW_07-8.5-Epithelial|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FRAS1 KSR2 CPM ADGRV1 PPL FREM2

2.38e-051941316f63ceedb88a9abc8644ee94adfd541e7817c1e3a
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_intermediate_(1)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CPXM2 CPM ADGRV1 PPL FREM2 MISP

2.45e-051951316d67a2b489c29bfd575751c13d2a5b1efdec5240a
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CPXM2 CPM ADGRV1 PPL FREM2 MISP

2.45e-051951316d673f8844896d5c7b76a7bc7f6b88a039f1bc263
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RAMP3 CPXM2 ID3 DNAJB4 PALMD MMRN2

2.52e-0519613165609b2d93172a488b35d854298a3a4e504e17e28
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-secretory_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PPL MPRIP MISP HNRNPUL2 CHD6 TPBG

2.52e-051961316547901c7a665770eff78eede69b8625b416c8186
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PPL MPRIP MISP HNRNPUL2 CHD6 TPBG

2.52e-0519613166e08d7ba67da161c2dca1a17c440ffb9d9b5bc3b
ToppCellCOVID_non-vent-Lymphocytic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

TRABD2A USP9Y MPRIP NFATC2 KMT2A HSP90AB1

2.59e-051971316c672915f8c8c1e948d251f6eaf9f84a5600c1193
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_capillary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RAMP3 ID3 PARVB PALMD SHROOM2 PRX

2.59e-05197131681718164c9802ee20c860ffbda7e62d5e9a76f16
ToppCellMS-CD4-naive_CD4|MS / Condition, Cell_class and T cell subcluster

TRABD2A KSR2 ID3 MPRIP CDCA7 RPL4

2.59e-051971316eb0d4849de4ca374bd9c1e138d4f2b9c19227b15
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RAMP3 CPXM2 ID3 DNAJB4 PALMD MMRN2

2.67e-0519813165784e0f9988c917026a692a61b09c7e77e540d13
ToppCellnormal_Lung-Endothelial_cells-Stalk-like_ECs|normal_Lung / Location, Cell class and cell subclass

FLNB SORBS2 RAMP3 ID3 PALMD MMRN2

2.67e-0519813162a251d13c2488d15ca9b11e643c1d17d428b6ef0
ToppCellPCW_10-12-Epithelial-Epithelial_airway|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CPXM2 CPM ADGRV1 PPL FREM2 MISP

2.67e-0519813169a12e5e47236433e512c668005fe3f8be6fde95c
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SORBS2 ACACA CPM ADGRV1 FREM2 SLC9C1

2.74e-0519913165f7da3eab58ace6cddb3179a415cd839d5767958
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_pulmonary_venous|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

FLNB SORBS2 RAMP3 ID3 PALMD MMRN2

2.74e-05199131615db14eff63d5edeced0738542d5fb739225511b
ToppCellTracheal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TRABD2A FLNB PCDH11Y FBP2 PALMD MMRN2

2.82e-0520013165ec31c1be6bcc4124e1489d136570f3de33cc2e9
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Myeloid-Megakaryocyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DNAJB1 TOPBP1 DNAJB4 CPM KMT2A PRMT9

2.82e-0520013160d76b006d8e8b32174e65e400acd0674354b962c
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Myeloid|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DNAJB1 TOPBP1 DNAJB4 CPM KMT2A PRMT9

2.82e-052001316cc8368665bc6bb7c4f39632ccff07ceaa98a7b65
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Prlr_(Entorhinal_cortex?)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

MROH2A ESR2 USP9Y PPL

4.05e-0565131457d0d892dab8bc8465067feeff279c967a43b781
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Prlr_(Entorhinal_cortex?)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

MROH2A ESR2 USP9Y PPL

4.05e-05651314aba26f607f35c2920cdf956309285ad9e7b758a7
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Sla|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PALMD RYR1 OTOF KRT77 SEC14L2

4.46e-051321315ddebc0b233fdbb73ceb70187945bbed8fd273f2a
ToppCellfacs-Heart-RA-24m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAMP3 ID3 PALMD USP9Y ABCC2

7.20e-051461315d903e091a917d3f5dcf82107e636520f75e47403
ToppCellfacs-Heart-RA-24m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAMP3 ID3 PALMD USP9Y ABCC2

7.20e-0514613159c9218e5257253597f2fd74fbd589b962d3078a3
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IL12RB2 CPXM2 HPS3 ZNF18 CDCA7

1.01e-0415713156730b775308f45a2f3946016bdbb7f8e5b5efe49
ToppCellICU-NoSEP-Lymphocyte-T_NK-Treg|ICU-NoSEP / Disease, Lineage and Cell Type

IL12RB2 ID3 USP9Y MPRIP ABCC2

1.08e-041591315d065ec02a4f3672ba53d4fea66029f1ce68f367f
ToppCellGlobus_pallidus-Neuronal-Excitatory|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

FRAS1 RYR1 OTOF KRT77 TPBG

1.11e-041601315f843287ed57d2d5a3b3f6dfb03b6934e330e6645
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor-epi-prox-progenitor_intermediate_|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FRAS1 PCDHGC5 CPXM2 PPL MISP

1.28e-041651315f6887c64af0f26e33316bc5587487e24d76ece2a
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC1-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ERN1 CPXM2 CBFA2T3 ABCA7 PRMT9

1.32e-041661315c8a7d94ed762e5e045ab5f74eef691ddc5f74993
ToppCelldroplet-Fat-Bat-18m-Myeloid-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDM5D NFATC2 OTOF ESPL1 PPP6R2

1.39e-0416813156fddc957a0503455d8c165862b5eb8e5fdb8a510
ToppCellControl|World / group, cell type (main and fine annotations)

SORBS2 ADGRV1 FREM2 SLC9C1 PER2

1.39e-041681315a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCelldroplet-Fat-Bat-18m-Myeloid-myeloid_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDM5D NFATC2 OTOF ESPL1 PPP6R2

1.39e-041681315794035cb63353a7d02fd9939deb5b4d075c9d95a
ToppCelldroplet-Fat-Bat-18m-Myeloid|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDM5D NFATC2 OTOF ESPL1 PPP6R2

1.39e-0416813151e23b634f96e88b976a523ca1f3fc08f6fe9b239
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ID3 PARVB PALMD CBFA2T3 MMRN2

1.43e-04169131558136b8a0bf2dab45c91a053ef7225ea49ccb871
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ID3 PARVB PALMD CBFA2T3 MMRN2

1.43e-04169131504c6ed38e1d1befba5ef5f37a3c1e045a0b163d6
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PEX6 ADGRV1 ACOT11 FUT8 KDM4B

1.47e-041701315ba4ba66b624089ed50a9083176386c7941b4c7a3
ToppCellE15.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FLNB PARVB PALMD CBFA2T3 MMRN2

1.60e-041731315b0ff9808e38cb64a734ced498cd0546728746cd5
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 ACOT11 MTOR CAPN7 AKAP11

1.64e-041741315f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RAMP3 CENPE NCAPG2 CDCA7 ESPL1

1.64e-041741315c26eac176e9b0cba385630fdc60e0314a4e4caac
ToppCellwk_15-18-Epithelial-Distal_epithelial-type_I_pneumocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

KRT4 CPM ADGRV1 PPL FREM2

1.64e-0417413152cd6638b361ca05ab83d09ce657194aed97873b7
ToppCellfacs-Heart-LV-24m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPM CBFA2T3 SFMBT2 ZP1 PGBD5

1.64e-041741315a0a059bb2a64d7011e206db2ebcdf3eb655a925a
ToppCellfacs-Heart-LV-24m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPM CBFA2T3 SFMBT2 ZP1 PGBD5

1.64e-0417413157cd6f9103133f8d7b90f9ff4b3b0b078cf554542
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IL12RB2 CENPE SHROOM2 EPG5 ESPL1

1.68e-0417513158958c5c30437d20a4abd70d7527990f7e2a68b93
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

NCAPG2 DNAH12 HMCN2 CDCA7 ESPL1

1.73e-0417613158813c01ea080f373fe3970c5e1ba4c2dca0f7f02
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNB ID3 PALMD CBFA2T3 MMRN2

1.73e-04176131527e6b3ae41068d6cfdda3d46da7df2a27567140e
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNB ID3 PALMD CBFA2T3 MMRN2

1.73e-041761315d6a5470af9592f34a741265f2ea9651c05c3add3
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PCDHGC5 CDHR5 CBFA2T3 BANP PRMT9

1.78e-0417713158887ff6341eb070bdaa890cc2cd7745f0cf1b0af
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PCDHGC5 CDHR5 CBFA2T3 BANP PRMT9

1.78e-041771315507f06d31ab773099c9431b6f433899dc97b5566
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 KSR2 ACOT11 CAPN7 AKAP11

1.82e-041781315fcbbcc44271515de1969b4732b6441c012693d5f
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

FRAS1 CPM ADGRV1 FREM2 SLC9C1

1.87e-041791315cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-OMD+_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FLNB CPXM2 NUP210L HMCN2 MMRN2

1.87e-0417913158c9ed247e1c4d655b81ce2f24a9936a7cade718a
ToppCellCOVID-19-Heart-EC_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

FLNB ESR2 PALMD MMRN2 FUT8

1.87e-0417913152a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

USP24 SREBF1 CPM ADGRV1 ACOT11

1.92e-0418013159e09b3dfe344b5d50520711513d389865d73a861
ToppCellfacs-Heart-RA-24m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAMP3 ID3 PALMD CBFA2T3 MMRN2

1.92e-041801315174c643e046646e3b305dd7e5b120d2c9a46690f
ToppCellrenal_papilla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

ESR2 KSR2 PPL SLC9C1 FUT8

1.92e-04180131549829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESR2 ID3 PARVB PALMD MMRN2

1.97e-0418113154d7793026373cbcf04b15c77f95f1025d07d4c00
ToppCellwk_20-22-Hematologic-Myeloid-pDC|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ERN1 CDHR5 CBFA2T3 ZP1 PRMT9

1.97e-04181131560607c5ff6d5b1cb416adc034491dca31c41e988
Diseaseautosomal dominant limb-girdle muscular dystrophy type 1 (implicated_via_orthology)

DNAJB1 DNAJB4 DNAJB5

3.10e-0741273DOID:0110305 (implicated_via_orthology)
Diseasecongenital myopathy 21 (implicated_via_orthology)

DNAJB1 DNAJB4 DNAJB5

3.10e-0741273DOID:0081353 (implicated_via_orthology)
DiseaseRhabdoid Tumor

SMARCB1 PGBD5

1.84e-0521272C0206743
DiseaseCarcinoma, Transitional Cell

ESR2 KMT2A CHD6 ESPL1

2.93e-05411274C0007138
DiseaseCryptophthalmos syndrome

FRAS1 FREM2

5.50e-0531272C0265233
DiseaseEMILIN-3 measurement

MMRN2 CHD6

5.50e-0531272EFO_0801563
DiseaseFRASER SYNDROME 1

FRAS1 FREM2

5.50e-0531272C4551480
Diseasehair colour measurement

ASXL1 FRAS1 MROH2A DNAJB4 ADGRV1 CBFA2T3 PKD1L3 EPG5 FREM2 BANP PPP6R3

7.40e-0561512711EFO_0007822
DiseaseFraser syndrome (implicated_via_orthology)

FRAS1 FREM2

1.10e-0441272DOID:0090001 (implicated_via_orthology)
DiseaseBladder Neoplasm

ESR2 MTOR KMT2A CHD6 ESPL1

3.58e-041401275C0005695
DiseaseMalignant neoplasm of urinary bladder

ESR2 MTOR KMT2A CHD6 ESPL1

3.70e-041411275C0005684
Diseaselimb-girdle muscular dystrophy (implicated_via_orthology)

OTOF FER1L4

3.81e-0471272DOID:11724 (implicated_via_orthology)
DiseaseUnilateral agenesis of kidney

FRAS1 FREM2

5.06e-0481272C0266294
Diseasemyelofibrosis (is_implicated_in)

ASXL1 KMT2A

5.06e-0481272DOID:4971 (is_implicated_in)
Diseasesystemic scleroderma, rheumatoid arthritis, myositis, systemic lupus erythematosus

IL12RB2 FLNB TNPO3

5.88e-04381273EFO_0000685, EFO_0000717, EFO_0000783, MONDO_0007915
Diseaseanti-centromere-antibody-positive systemic scleroderma

PARVB TNPO3

6.49e-0491272EFO_0008536
Diseasealcohol consumption measurement

ACACA FARSB QRICH1 ADGRV1 PKD1L3 BIRC6 SH2B1 FAM135B ADH4 NFATC2 MTOR AKAP11 FUT8 PPP6R3

9.41e-04124212714EFO_0007878
DiseaseProstatic Neoplasms

ESR2 PCDH11Y ID3 PPL KMT2A CHD6 CNOT3 TPBG HSP90AB1

1.42e-036161279C0033578
DiseaseMalignant neoplasm of prostate

ESR2 PCDH11Y ID3 PPL KMT2A CHD6 CNOT3 TPBG HSP90AB1

1.42e-036161279C0376358
Diseasenervous system disorder

ID3 NFATC2 ABCC2

1.56e-03531273C0027765
DiseaseCarcinoma, Granular Cell

ESR2 ID3 MTOR KMT2A

1.62e-031161274C0205644
DiseaseAdenocarcinoma, Tubular

ESR2 ID3 MTOR KMT2A

1.62e-031161274C0205645
DiseaseAdenocarcinoma, Oxyphilic

ESR2 ID3 MTOR KMT2A

1.62e-031161274C0205642
DiseaseCarcinoma, Cribriform

ESR2 ID3 MTOR KMT2A

1.62e-031161274C0205643
DiseaseAdenocarcinoma, Basal Cell

ESR2 ID3 MTOR KMT2A

1.62e-031161274C0205641
DiseaseAdenocarcinoma

ESR2 ID3 MTOR KMT2A

1.62e-031161274C0001418
Diseasepulmonary hypertension (implicated_via_orthology)

ESR2 NFATC2 MTOR

1.65e-03541273DOID:6432 (implicated_via_orthology)
Diseaseage at menopause

ACACA IPO7 BIRC6 BANP CHD6 TNPO3

2.01e-033021276EFO_0004704
Diseasefibrinogen measurement, factor VII measurement

PKD1L3 ADH4 HDLBP

2.02e-03581273EFO_0004619, EFO_0004623
DiseaseSpermatogenic Failure, Nonobstructive, Y-Linked

KDM5D USP9Y

2.12e-03161272C1839071
DiseaseSpermatogenic failure, Y-linked, 2

KDM5D USP9Y

2.12e-03161272cv:C1839071
DiseaseSPERMATOGENIC FAILURE, Y-LINKED, 2

KDM5D USP9Y

2.12e-03161272415000
Diseasemean reticulocyte volume

NUP210L CBFA2T3 ABCA7 SH2B1 HPS3 BRAP CDCA7 MTOR HDLBP HSP90AB1

2.44e-0379912710EFO_0010701
DiseaseAPOE carrier status, dementia

SORBS2 FAM135B ADH4

2.45e-03621273EFO_0007659, MONDO_0001627
DiseaseTinnitus

KRT4 KRT79 NFATC2 CDCA7

2.45e-031301274HP_0000360
DiseaseAlzheimer disease, gastroesophageal reflux disease

CENPE SREBF1 FAM135B GCNT7 DNAH12

3.12e-032281275EFO_0003948, MONDO_0004975
Diseaseend stage renal disease (implicated_via_orthology)

MTOR ABCC2

3.32e-03201272DOID:783 (implicated_via_orthology)
DiseaseNon-alcoholic Fatty Liver Disease

SREBF1 ADH4 ABCC2

3.45e-03701273C0400966
DiseaseNonalcoholic Steatohepatitis

SREBF1 ADH4 ABCC2

3.45e-03701273C3241937
Diseasechildhood trauma measurement, alcohol consumption measurement

PCDHGC5 KSR2 SFMBT2

3.60e-03711273EFO_0007878, EFO_0007979
DiseaseN-glycan measurement

SMARCB1 FUT8

4.01e-03221272EFO_0004999
Diseaseproprotein convertase subtilisin/kexin type 9 measurement

KSR2 USP24

4.01e-03221272EFO_0009312

Protein segments in the cluster

PeptideGeneStartEntry
VQIAVEDLSPDHPVV

BANP

11

Q8N9N5
HPEIISVLLDRVQET

EPG5

831

Q9HCE0
VVIRLELAEHSPVPA

BRAP

6

Q7Z569
VQDPPVVHELRVSLE

DNAJB5

166

O75953
SLDIEIPKHIPERVS

PRMT9

236

Q6P2P2
RPTIHLCEIVNEPQL

BIRC6

2366

Q9NR09
EQQLVHVERPILRIP

DNPEP

161

Q9ULA0
DHPLLQEREKIVAPI

PGLS

161

O95336
EVEVAPPKAHEVRIQ

ADH4

26

P08319
LENHRREQEVPPVII

ACTL8

86

Q9H568
QQIRTEPILPEIHFL

ADAM7

721

Q9H2U9
LVPEEDHILIIPVVR

ADGRV1

271

Q8WXG9
PRDEPIHILNVAIKT

ACACA

1281

Q13085
EKTRVESVELVLPPH

ACOT11

216

Q8WXI4
IEAVVHPREVDPFIL

AKAP11

1306

Q9UKA4
TEPLVDIHVPEGQEV

CDHR5

46

Q9HBB8
DPPVTHDLRVSLEEI

DNAJB1

161

P25685
VAERLVEQPQLHPDV

ASXL1

771

Q8IXJ9
VPGARLVEELPHELV

ABCA7

1086

Q8IZY2
IEDPVPTLHLTERDI

CNOT3

556

O75175
VEETRIHVLPSLNPD

CPXM2

411

Q8N436
VDRVHLEDPPDEVLI

RAMP3

106

O60896
LHEVLKDVQPRVTPL

QRICH1

581

Q2TAL8
LSKPEVVIIHDAVRP

CRPPA

146

A4D126
EVPVTIVRGPHDLEV

OBSL1

1626

O75147
ATDHQELVEIPTRPL

MISP

316

Q8IVT2
PRIEITPSHELIQAV

NFATC2

111

Q13469
VPHPRSVIQQAEEKL

PALMD

326

Q9NP74
LEINPDHPIVETLRQ

HSP90AB1

626

P08238
HQVETTPLREEKQVP

MPRIP

641

Q6WCQ1
DVVIEIIDPPLHGQL

FRAS1

1251

Q86XX4
EQLVLTLLEAEPPHV

ESR2

266

Q92731
PELRVPVPEVLLHSE

INTS1

1811

Q8N201
PDRSLEQVLLPHVDT

MMRN2

221

Q9H8L6
DVELVVQVPPRIHPT

HMCN2

966

Q8NDA2
ENQVPSVRVEIHLPR

PHKA1

741

P46020
QSLLTPLHVEIDPEI

KRT79

121

Q5XKE5
PLHVEIDPEIQRVRT

KRT79

126

Q5XKE5
HLAPEIIRQLSPDTE

KSR2

831

Q6VAB6
VNVRPVDDEVPILSH

FREM2

931

Q5SZK8
GRREHLQEEPPLVII

FER1L4

821

A9Z1Z3
RVHLLEVEQPQVVLE

FER1L4

951

A9Z1Z3
TELVRHLTVDLPEQP

FER1L4

986

A9Z1Z3
DPEPLVISEVLHQVT

IL12RB2

701

Q99665
AIIRETENIPVHLPN

KDM5D

991

Q9BY66
QSLLTPLHVEIDPEI

KRT4

116

P19013
PLHVEIDPEIQKVRT

KRT4

121

P19013
QPVLDVKPEAIHQRV

FBP2

301

O00757
VPQVITPEEIIHPDV

FLNB

211

O75369
LIETPVLVQLHPSDR

PER2

361

O15055
ELTEQIHRLLLQPVP

PER2

461

O15055
IRENIVEAIIHSPEL

IPO7

91

O95373
VQVVTEHPLELIRVE

PCDHGC5

106

Q9Y5F6
LLRQQPEVEVTHETL

PPL

866

O60437
EVEQVIPLPSHEEVT

PDE12

571

Q6L8Q7
EILETIQLPLEHPEL

PEX6

716

Q13608
IIREKLLEHLPQEVP

ERAL1

351

O75616
IHAVPVEERVRTAVP

HNRNPUL2

431

Q1KMD3
EILSETKDPLRVQPH

DNAH12

1006

Q6ZR08
NVIERHPVDISAIPE

KDM4B

831

O94953
ESVPLNLPESLRVIH

OGN

226

P20774
THPTVREQIPLLEQK

MMAA

381

Q8IVH4
HDLREKLTIIPQDPI

ABCC2

1371

Q92887
LESEPIVYRRIIVPH

EDC3

251

Q96F86
VNHVPVVTEELLTLP

MIER3

431

Q7Z3K6
PLVVPGSRQEEVIDH

CBFA2T3

371

O75081
GHRIEEVPELPLVVE

RPL4

141

P36578
TRTEVEVEELPPIDH

IMPACT

161

Q9P2X3
PIRLPEHVTVQVVVV

PARVB

196

Q9HBI1
QTQVLHEPLIDEDPV

PGBD5

251

Q8N414
QDPPVIHELRVSLEE

DNAJB4

156

Q9UDY4
EVPRPEQVQEALTKH

ESPL1

1981

Q14674
IPERTVEFQHIIPIS

GTPBP10

311

A4D1E9
PLPNVIVEVQDRKHI

CPM

326

P14384
VPRKVIIDDQLPVDH

CAPN7

341

Q9Y6W3
RLQVLRQAEVPIEPH

GCNT7

401

Q6ZNI0
LKEDPVLQVPTHVEE

ERN1

56

O75460
ERPEVLHLTEPTTNI

CHD6

1886

Q8TD26
EVIHVPSPALEERKT

DPP9

286

Q86TI2
DRVHVLPGPVETVEL

PRMT6

131

Q96LA8
PVISRHVTQDIVLPD

CYP4F2

396

P78329
IQVLPEERSDTPEVH

KMT2A

496

Q03164
HLPIQTAELTPELVI

ID3

96

Q02535
PEHRRLPILVQLVDT

HEATR1

1391

Q9H583
IPELPHTELEALAVE

FAM135B

266

Q49AJ0
QPESEVLVHIPKQRL

C1orf127

96

Q8N9H9
EVLLKHISPDQVPVE

SEC14L2

226

O76054
DTVQIVLPPHLERIR

RYR1

856

P21817
EIPVLHEEQELLPNV

CENPE

1281

Q02224
PEHPLTLEELNVVEQ

CIAO2B

56

Q9Y3D0
VIQRLVELIHPSQDE

PPP6R2

191

O75170
EAHELRDDPPIIVIE

OTOF

1021

Q9HC10
LVPRHSEVFLQLPVE

NUP210L

1226

Q5VU65
ITIKEPLDREETPNH

PCDH11Y

341

Q9BZA8
IIDRTVPPETLHIDE

IPO8

236

O15397
PHRPLLVDLTVEEGQ

MINK1

1161

Q8N4C8
IHPIVRTLDQSPELR

MTOR

1156

P42345
LPVVDHPEVRRLLID

MROH2A

1131

A6NES4
RPPLEAAIHDIVQLV

GRIN3B

286

O60391
VQVVELPIVDSLHPR

FUT8

286

Q9BYC5
ELVPVVELVPVVELE

SH2B1

691

Q9NRF2
TEEPRINLPHLLEEE

PTAR1

281

Q7Z6K3
IIRPLTVEEVLYHIP

SLC9C1

856

Q4G0N8
VQVPEEPTHLDQRVI

MIA3

1076

Q5JRA6
ERSLIIHIDNITPVE

HPS3

176

Q969F9
VQELERVPHNTPVDV

NBR1

571

Q14596
ETHILPTEQEPSREV

PKD1L3

1116

Q7Z443
ELRVAPEEHPILLTE

POTEJ

756

P0CG39
EENEVTEHTPLLRPL

RNF13

301

O43567
ILDVSLDPQERPQHV

SHROOM2

901

Q13796
IHENASQPEVLVPIR

SMARCB1

176

Q12824
PLKEIVVIHQDPEAL

IARS1

846

P41252
LVPIHIEVTSDEQPR

SORBS2

576

O94875
QIEIEIPPTRADIIH

FARSB

346

Q9NSD9
VEHLPRVLQESERPL

SREBF1

901

P36956
EERYERIEIPIHIVP

BRCC3

206

P46736
PHIIRPVEEITEEEL

CDCA7

236

Q9BWT1
HQLRKVSDVEELTPP

NCAPG2

1021

Q86XI2
YPIVRLLREPVHVEV

ZP1

426

P60852
HLPEVQLPKVSEIRL

PRX

741

Q9BXM0
IIIQHENIFPSPREL

SRGAP2

671

O75044
HLEGLQTPVPEVIVD

SFMBT2

441

Q5VUG0
VEIHVDSVLPVPPIE

PRRC2B

1771

Q5JSZ5
DIVPQLQVPVLDRHI

TRABD2A

446

Q86V40
FIPVIEIVPHLLENL

USP9Y

276

O00507
EPVPLQHGDRITIEI

VCPIP1

836

Q96JH7
PFLLEILTVLPEEVH

TNPO3

141

Q9Y5L0
LHEILVIEDPIQVER

USP24

2456

Q9UPU5
VELILNHIVPPEDER

TPBG

176

Q13641
VGEVEPHLEVVPQEL

ZNF18

151

P17022
VPVTIEVEVPFDLHR

HDLBP

971

Q00341
HRVSLNILPPEEEEE

TREML1

116

Q86YW5
IIQRLVEIVHPSQEE

PPP6R3

191

Q5H9R7
VAPHPREKIITIEET

TOPBP1

1246

Q92547
ILRPPVVHVDPDILQ

USP33

916

Q8TEY7
PLEHKIIIRVQTTPD

POLR2J

66

P52435
LEPLHLEVDPEIQRI

KRT77

146

Q7Z794