Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpeptide lactyltransferase (CoA-dependent) activity

CREBBP EP300

6.91e-062532GO:0120300
GeneOntologyMolecularFunctionhistone H3K27 acetyltransferase activity

CREBBP EP300

6.91e-062532GO:0044017
GeneOntologyMolecularFunctionhistone H3K18 acetyltransferase activity

CREBBP EP300

2.07e-053532GO:0043993
GeneOntologyMolecularFunctionribonuclease A activity

RNASE2 RNASE8

6.88e-055532GO:0004522
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 3'-phosphomonoesters

RNASE2 RNASE8

1.92e-048532GO:0016892
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

CREBBP EP300

7.10e-0415532GO:0010484
GeneOntologyMolecularFunctionprotein kinase C binding

HDAC9 NELL1 RBCK1

7.18e-0466533GO:0005080
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP1 LRP1B

8.10e-0416532GO:0005041
GeneOntologyMolecularFunctionp53 binding

CREBBP EP300 HTT

1.12e-0377533GO:0002039
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters

RNASE2 RNASE8

1.27e-0320532GO:0016894
GeneOntologyMolecularFunctionperoxisome proliferator activated receptor binding

CREBBP EP300

1.41e-0321532GO:0042975
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP1 LRP1B

1.41e-0321532GO:0030228
GeneOntologyMolecularFunctionzinc ion binding

ZFHX4 TRIM42 ARIH2 ADAMTS20 ZNF407 CREBBP LIN28A EP300

2.27e-03891538GO:0008270
HumanPhenoAortic isthmus hypoplasia

CREBBP EP300

8.09e-062152HP:0034227
HumanPhenoPlantar crease between first and second toes

CREBBP EP300

8.09e-062152HP:0008107
HumanPhenoHigh axial triradius

CREBBP EP300

8.09e-062152HP:0001042
HumanPhenoAbsent earlobe

ZNF407 CREBBP EP300

2.29e-0520153HP:0000387
HumanPhenoHumoral immunodeficiency

CREBBP EP300

2.42e-053152HP:0005363
HumanPhenoProminent nasal septum

CREBBP EP300

2.42e-053152HP:0005322
HumanPhenoRadial deviation of thumb terminal phalanx

CREBBP EP300

2.42e-053152HP:0005895
HumanPhenoLaryngeal cartilage malformation

CREBBP EP300

2.42e-053152HP:0008752
HumanPhenoPhobia

CREBBP EP300

2.42e-053152HP:5200232
HumanPhenoAgoraphobia

CREBBP EP300

2.42e-053152HP:0000756
HumanPhenoTrichiasis

CREBBP EP300

4.84e-054152HP:0001128
HumanPhenoWidened distal phalanges

CREBBP EP300

4.84e-054152HP:0006200
HumanPhenoVisceral hemangioma

CREBBP EP300

4.84e-054152HP:0410266
HumanPhenoTalon cusp

CREBBP EP300

4.84e-054152HP:0011087
HumanPhenoVascular ring

CREBBP EP300

4.84e-054152HP:0010775
HumanPhenoHepatic hemangioma

CREBBP EP300

4.84e-054152HP:0031207
HumanPhenoPapillary cystadenoma of the epididymis

CREBBP EP300

8.05e-055152HP:0009715
HumanPhenoSupernumerary cusp

CREBBP EP300

8.05e-055152HP:0033777
HumanPhenoEpididymal neoplasm

CREBBP EP300

8.05e-055152HP:0030421
HumanPhenoLarge foramen magnum

CREBBP EP300

1.21e-046152HP:0002700
HumanPhenoDeviated nasal septum

CREBBP EP300

1.69e-047152HP:0004411
HumanPhenoPilomatrixoma

CREBBP EP300

2.88e-049152HP:0030434
HumanPhenoCervical cord compression

CREBBP EP300

2.88e-049152HP:0002341
HumanPhenoProminent fingertip pads

ZNF407 CREBBP EP300

2.91e-0446153HP:0001212
HumanPhenoBicuspid aortic valve

FBN2 MYLK CREBBP EP300

3.17e-04119154HP:0001647
HumanPhenoProminent digit pad

ZNF407 CREBBP EP300

3.30e-0448153HP:0011298
HumanPhenoAbnormal aortic valve cusp morphology

FBN2 MYLK CREBBP EP300

3.38e-04121154HP:0031567
HumanPhenoFrontal hirsutism

CREBBP EP300

3.59e-0410152HP:0011335
HumanPhenoAbnormal subclavian artery morphology

CREBBP EP300

4.38e-0411152HP:0031251
HumanPhenoAplasia/Hypoplasia of the earlobes

ZNF407 CREBBP EP300

4.43e-0453153HP:0009906
HumanPhenoFacial grimacing

CREBBP EP300

6.20e-0413152HP:0000273
HumanPhenoKeloids

CREBBP EP300

6.20e-0413152HP:0010562
HumanPhenoParietal foramina

CREBBP EP300

7.22e-0414152HP:0002697
HumanPhenoDuplication of phalanx of hallux

CREBBP EP300

7.22e-0414152HP:0010066
HumanPhenoHypoplastic aortic arch

CREBBP EP300

7.22e-0414152HP:0012304
HumanPhenoSocial and occupational deterioration

CREBBP EP300

8.31e-0415152HP:0007086
HumanPhenoDuplication of phalanx of toe

CREBBP EP300

8.31e-0415152HP:0010181
HumanPhenoIntestinal malrotation

FBN2 MYLK CREBBP EP300

9.09e-04157154HP:0002566
HumanPhenoSquare face

CREBBP EP300

9.48e-0416152HP:0000321
HumanPhenoPatellar dislocation

FBN2 CREBBP EP300

1.05e-0371153HP:0002999
HumanPhenoPremature thelarche

CREBBP EP300

1.07e-0317152HP:0010314
HumanPhenoOverlapping toe

ZNF407 CREBBP EP300

1.09e-0372153HP:0001845
HumanPhenoAtypical scarring of skin

LRP1 CREBBP EP300

1.18e-0374153HP:0000987
HumanPhenoFacial hirsutism

CREBBP EP300

1.21e-0318152HP:0009937
HumanPhenoSkin appendage neoplasm

CREBBP EP300

1.21e-0318152HP:0012842
HumanPhenoLocalized hirsutism

CREBBP EP300

1.65e-0321152HP:0009889
HumanPhenoDeep plantar creases

CREBBP EP300

1.65e-0321152HP:0001869
HumanPhenoCorneal scarring

CREBBP EP300

1.65e-0321152HP:0000559
HumanPhenoElbow dislocation

FBN2 CREBBP EP300

1.71e-0384153HP:0003042
DomainLRRC37AB_C

LRRC37A LRRC37A3 LRRC37A2 LRRC37B

8.37e-114584PF14914
DomainLRRC37_N

LRRC37A LRRC37A3 LRRC37A2 LRRC37B

8.37e-114584IPR032754
DomainLRRC37AB_C

LRRC37A LRRC37A3 LRRC37A2 LRRC37B

8.37e-114584IPR029423
DomainLRRC37

LRRC37A LRRC37A3 LRRC37A2 LRRC37B

8.37e-114584PF15779
DomainLRRC37A/B-like

LRRC37A LRRC37A3 LRRC37A2 LRRC37B

8.37e-114584IPR015753
DomainRNaseA_AS

RNASE2 RNASE6 RNASE8

1.57e-068583IPR023411
DomainRNASE_PANCREATIC

RNASE2 RNASE6 RNASE8

1.57e-068583PS00127
DomainRNAse_Pc

RNASE2 RNASE6 RNASE8

4.61e-0611583SM00092
DomainRNaseA

RNASE2 RNASE6 RNASE8

7.95e-0613583PD000535
DomainNuc_rcpt_coact_CREBbp

CREBBP EP300

9.48e-062582IPR014744
DomainHAT_KAT11

CREBBP EP300

9.48e-062582PF08214
DomainKIX

CREBBP EP300

9.48e-062582PS50952
DomainZnF_TAZ

CREBBP EP300

9.48e-062582SM00551
DomainCBP_P300_HAT

CREBBP EP300

9.48e-062582IPR031162
DomainDUF5050

LRP1 LRP1B

9.48e-062582IPR032485
DomainDUF902

CREBBP EP300

9.48e-062582PF06001
Domain-

CREBBP EP300

9.48e-0625821.20.1020.10
DomainRING_CBP-p300

CREBBP EP300

9.48e-062582IPR010303
Domain-

CREBBP EP300

9.48e-0625821.10.1630.10
DomainCreb_binding

CREBBP EP300

9.48e-062582PF09030
Domain-

CREBBP EP300

9.48e-0625821.10.246.20
Domainzf-TAZ

CREBBP EP300

9.48e-062582PF02135
DomainZF_TAZ

CREBBP EP300

9.48e-062582PS50134
DomainHistone_AcTrfase_Rtt109/CBP

CREBBP EP300

9.48e-062582IPR013178
DomainDUF5050

LRP1 LRP1B

9.48e-062582PF16472
DomainKAT11

CREBBP EP300

9.48e-062582SM01250
DomainZnf_TAZ

CREBBP EP300

9.48e-062582IPR000197
DomainKIX_dom

CREBBP EP300

9.48e-062582IPR003101
DomainKIX

CREBBP EP300

9.48e-062582PF02172
DomainCBP_P300_HAT

CREBBP EP300

9.48e-062582PS51727
DomainRNaseA

RNASE2 RNASE6 RNASE8

1.26e-0515583IPR001427
DomainRNaseA_domain

RNASE2 RNASE6 RNASE8

1.26e-0515583IPR023412
DomainRnaseA

RNASE2 RNASE6 RNASE8

1.26e-0515583PF00074
Domain-

RNASE2 RNASE6 RNASE8

1.26e-05155833.10.130.10
DomaincEGF

FBN2 LRP1 LRP1B

7.02e-0526583IPR026823
DomaincEGF

FBN2 LRP1 LRP1B

7.02e-0526583PF12662
DomainNuc_rcpt_coact

CREBBP EP300

1.41e-046582IPR009110
DomainEGF_CA

NELL1 FBN2 LRP1 LRP1B

1.47e-0486584PF07645
DomainLRR_8

LRRC37A LRRC37A3 LRRC37A2 LRRC37B LRRC8D

1.88e-04171585PF13855
DomainLeu-rich_rpt_typical-subtyp

LRRC37A LRRC37A3 LRRC37A2 LRRC37B LRRC8D

2.20e-04177585IPR003591
DomainLRR_TYP

LRRC37A LRRC37A3 LRRC37A2 LRRC37B LRRC8D

2.20e-04177585SM00369
DomainEGF_Ca-bd_CS

NELL1 FBN2 LRP1 LRP1B

2.34e-0497584IPR018097
DomainEGF_CA

NELL1 FBN2 LRP1 LRP1B

2.53e-0499584PS01187
DomainASX_HYDROXYL

NELL1 FBN2 LRP1 LRP1B

2.63e-04100584PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

NELL1 FBN2 LRP1 LRP1B

3.29e-04106584IPR000152
DomainLRR

LRRC37A LRRC37A3 LRRC37A2 LRRC37B LRRC8D

3.96e-04201585PS51450
DomainEGF_CA

NELL1 FBN2 LRP1 LRP1B

5.60e-04122584SM00179
DomainLRR_1

LRRC37A LRRC37A3 LRRC37A2 LRRC37B LRRC8D

5.85e-04219585PF00560
DomainEGF-like_Ca-bd_dom

NELL1 FBN2 LRP1 LRP1B

5.95e-04124584IPR001881
DomainLdl_recept_b

LRP1 LRP1B

8.42e-0414582PF00058
DomainLDLRB

LRP1 LRP1B

8.42e-0414582PS51120
DomainIBR

ARIH2 RBCK1

8.42e-0414582PF01485
DomainIBR_dom

ARIH2 RBCK1

9.70e-0415582IPR002867
DomainLY

LRP1 LRP1B

9.70e-0415582SM00135
DomainLDLR_classB_rpt

LRP1 LRP1B

9.70e-0415582IPR000033
DomainGrowth_fac_rcpt_

NELL1 FBN2 LRP1 LRP1B

1.40e-03156584IPR009030
DomainZZ

CREBBP EP300

1.40e-0318582PF00569
DomainZF_ZZ_2

CREBBP EP300

1.40e-0318582PS50135
DomainZF_ZZ_1

CREBBP EP300

1.40e-0318582PS01357
DomainLeu-rich_rpt

LRRC37A LRRC37A3 LRRC37A2 LRRC37B LRRC8D

1.52e-03271585IPR001611
DomainZnf_ZZ

CREBBP EP300

1.57e-0319582IPR000433
DomainZnF_ZZ

CREBBP EP300

1.57e-0319582SM00291
DomainZnf_RING_CS

TRIM42 ARIH2 RNF183 RBCK1

1.64e-03163584IPR017907
DomainGPCR_3

GPR158 GPRC6A

1.92e-0321582IPR000337
DomainZF_RING_1

RNF123 TRIM42 ARIH2 RNF183 RBCK1

2.07e-03291585PS00518
Domain7tm_3

GPR158 GPRC6A

2.10e-0322582PF00003
DomainG_PROTEIN_RECEP_F3_2

GPR158 GPRC6A

2.10e-0322582PS00980
DomainG_PROTEIN_RECEP_F3_3

GPR158 GPRC6A

2.10e-0322582PS00981
DomainG_PROTEIN_RECEP_F3_1

GPR158 GPRC6A

2.10e-0322582PS00979
DomainG_PROTEIN_RECEP_F3_4

GPR158 GPRC6A

2.10e-0322582PS50259
DomainGPCR_3_C

GPR158 GPRC6A

2.10e-0322582IPR017978
DomainZF_RING_2

RNF123 TRIM42 ARIH2 RNF183 RBCK1

2.30e-03298585PS50089
DomainRING

RNF123 TRIM42 ARIH2 RNF183 RBCK1

2.54e-03305585SM00184
DomainZnf_RING/FYVE/PHD

RNF123 TRIM42 ZNF423 ARIH2 RNF183 RBCK1

2.93e-03459586IPR013083
DomainBromodomain_CS

CREBBP EP300

2.94e-0326582IPR018359
Domain-

LRRC37A LRRC37A3 LRRC37A2 LRRC37B LRRC8D

3.16e-033215853.80.10.10
DomainZnf_RING

RNF123 TRIM42 ARIH2 RNF183 RBCK1

3.38e-03326585IPR001841
PathwayWP_TGFBETA_SIGNALING_PATHWAY

LIF ZNF423 CREBBP EP300

1.20e-0553384MM15880
PathwayWP_TGFBETA_RECEPTOR_SIGNALING

LIF ZNF423 CREBBP EP300

1.39e-0555384M39351
PathwayWP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS

LIF ZNF423 CREBBP EP300

1.84e-0559384M39886
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

7.04e-055382MM1575
PathwayREACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES

CREBBP EP300

7.04e-055382M48020
PathwayREACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION

CREBBP EP300

7.04e-055382M27228
PathwayREACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES

CREBBP EP300

7.04e-055382M48023
PathwayWP_INITIATION_OF_TRANSCRIPTION_AND_TRANSLATION_ELONGATION_AT_THE_HIV1_LTR

HDAC9 CREBBP EP300

8.49e-0532383M39521
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

1.05e-046382M22062
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

1.47e-047382MM1573
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

1.96e-048382M22058
PathwayREACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES

CREBBP EP300

1.96e-048382M48022
PathwayREACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION

CREBBP EP300

1.96e-048382M48024
PathwayREACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES

CREBBP EP300

1.96e-048382M46443
PathwayKEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY

CREBBP EP300

2.52e-049382M47451
PathwayREACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

HDAC9 CREBBP EP300

2.87e-0448383M611
PathwayREACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION

CREBBP EP300

3.14e-0410382M27945
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

3.83e-0411382MM1521
PathwayREACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES

CREBBP EP300

3.83e-0411382M48021
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_BY_HYPOXIA_INDUCIBLE_FACTOR

CREBBP EP300

3.83e-0411382M26924
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

4.59e-0412382M7968
PathwayREACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS

CREBBP EP300

4.59e-0412382M27765
PathwayPID_P53_DOWNSTREAM_PATHWAY

LIF CREBBP EP300 HTT

4.88e-04137384M145
PathwayREACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER

HDAC9 CREBBP EP300

5.03e-0458383M29616
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

CREBBP EP300

6.31e-0414382M27808
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

7.27e-0415382MM1339
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

7.27e-0415382M10183
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

7.27e-0415382MM1439
PathwayREACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY

CREBBP EP300

7.27e-0415382M953
PathwayPID_HDAC_CLASSI_PATHWAY

HDAC9 CREBBP EP300

7.36e-0466383M101
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

8.29e-0416382M1296
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

8.29e-0416382MM1420
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

8.29e-0416382M8516
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS

CREBBP EP300

8.29e-0416382M27121
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_DEATH_GENES

CREBBP EP300

8.29e-0416382M27940
PathwayBIOCARTA_TGFB_PATHWAY

CREBBP EP300

9.38e-0417382MM1509
PathwayREACTOME_ZYGOTIC_GENOME_ACTIVATION_ZGA

CREBBP EP300

9.38e-0417382M48025
PathwayREACTOME_SIGNALING_BY_NOTCH1

HDAC9 CREBBP EP300

1.03e-0374383M616
PathwayREACTOME_RORA_ACTIVATES_GENE_EXPRESSION

CREBBP EP300

1.05e-0318382M26942
PathwayBIOCARTA_TGFB_PATHWAY

CREBBP EP300

1.18e-0319382M18933
PathwayREACTOME_NFE2L2_REGULATING_ANTI_OXIDANT_DETOXIFICATION_ENZYMES

CREBBP EP300

1.18e-0319382M46442
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

CREBBP EP300

1.30e-0320382M27881
PathwayWP_HEMATOPOIETIC_STEM_CELL_GENE_REGULATION_BY_GABP_ALPHABETA_COMPLEX

CREBBP EP300

1.44e-0321382M39593
PathwayREACTOME_CD209_DC_SIGN_SIGNALING

CREBBP EP300

1.44e-0321382M27485
PathwayBIOCARTA_NTHI_PATHWAY

CREBBP EP300

1.58e-0322382MM1443
PathwayBIOCARTA_VDR_PATHWAY

CREBBP EP300

1.58e-0322382MM1370
PathwayBIOCARTA_NTHI_PATHWAY

CREBBP EP300

1.73e-0323382M2821
PathwayBIOCARTA_VDR_PATHWAY

CREBBP EP300

1.88e-0324382M13404
PathwayREACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

CREBBP EP300

2.04e-0325382M27880
PathwayBIOCARTA_CARM_ER_PATHWAY

CREBBP EP300

2.21e-0326382M2499
PathwayPID_HDAC_CLASSIII_PATHWAY

CREBBP EP300

2.21e-0326382M32
PathwayWP_MICRORNAS_IN_CARDIOMYOCYTE_HYPERTROPHY

HDAC9 LIF MYLK

2.37e-0399383MM15905
PathwayREACTOME_ATTENUATION_PHASE

CREBBP EP300

2.56e-0328382M27254
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

HDAC9 CREBBP

2.56e-0328382M6177
PathwayWP_MICRORNAS_IN_CARDIOMYOCYTE_HYPERTROPHY

HDAC9 LIF MYLK

2.73e-03104383M39625
PathwayPID_RETINOIC_ACID_PATHWAY

CREBBP EP300

2.93e-0330382M207
PathwayREACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION

CREBBP EP300

2.93e-0330382M936
PathwayREACTOME_ADIPOGENESIS

ZNF423 CREBBP EP300

3.20e-03110383M48259
PathwayWP_HDAC6_INTERACTIONS_IN_THE_CENTRAL_NERVOUS_SYSTEM

HDAC9 EP300 HTT

3.45e-03113383M48336
PathwayWP_TYPE_2_PAPILLARY_RENAL_CELL_CARCINOMA

CREBBP EP300

3.76e-0334382M39771
PathwayPID_HIF2PATHWAY

CREBBP EP300

3.76e-0334382M44
PathwayREACTOME_EVASION_BY_RSV_OF_HOST_INTERFERON_RESPONSES

CREBBP EP300

3.98e-0335382M48246
PathwayREACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS

ZNF335 CREBBP EP300

4.28e-03122383M29689
PathwayPID_FRA_PATHWAY

LIF EP300

4.44e-0337382M65
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_THE_AP_2_TFAP2_FAMILY_OF_TRANSCRIPTION_FACTORS

CREBBP EP300

4.68e-0338382M27757
PathwayREACTOME_HSF1_DEPENDENT_TRANSACTIVATION

CREBBP EP300

4.68e-0338382M27255
PathwayPID_FOXM1_PATHWAY

CREBBP EP300

5.17e-0340382M176
PathwayPID_IFNG_PATHWAY

CREBBP EP300

5.17e-0340382M161
PathwayREACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT

CREBBP EP300

5.69e-0342382M17541
Pubmed

Evolutionary dynamism of the primate LRRC37 gene family.

LRRC37A LRRC37A3 LRRC37A2 LRRC37B

1.45e-091058423064749
Pubmed

Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.

LRRC37A LRRC37A3 LRRC37A2

1.76e-08458322419166
Pubmed

Loss of p300 accelerates MDS-associated leukemogenesis.

CREBBP EP300

2.73e-06258227881875
Pubmed

Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.

CREBBP EP300

2.73e-06258234845315
Pubmed

Striking differences of LDL receptor-related protein 1B expression in mouse and human.

LRP1 LRP1B

2.73e-06258215963947
Pubmed

p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.

CREBBP EP300

2.73e-06258219729597
Pubmed

Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.

CREBBP EP300

2.73e-06258215860545
Pubmed

Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.

CREBBP EP300

2.73e-06258229460469
Pubmed

Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.

CREBBP EP300

2.73e-06258224551300
Pubmed

Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.

CREBBP EP300

2.73e-06258233911074
Pubmed

The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.

CREBBP EP300

2.73e-0625829018065
Pubmed

Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.

CREBBP EP300

2.73e-06258224648406
Pubmed

CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.

CREBBP EP300

2.73e-06258230135524
Pubmed

CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.

CREBBP EP300

2.73e-06258239287984
Pubmed

Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.

CREBBP EP300

2.73e-06258216596650
Pubmed

The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.

CREBBP EP300

2.73e-06258229217654
Pubmed

Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.

CREBBP EP300

2.73e-06258220717166
Pubmed

Mutant huntingtin represses CBP, but not p300, by binding and protein degradation.

CREBBP HTT

2.73e-06258216456924
Pubmed

Differences in the interactions of oncogenic adenovirus 12 early region 1A and nononcogenic adenovirus 2 early region 1A with the cellular coactivators p300 and CBP.

CREBBP EP300

2.73e-06258210049825
Pubmed

CBP/p300 acetyltransferase activity in hematologic malignancies.

CREBBP EP300

2.73e-06258227380996
Pubmed

CREBBP and p300 lysine acetyl transferases in the DNA damage response.

CREBBP EP300

2.73e-06258229170789
Pubmed

The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.

CREBBP EP300

2.73e-06258225893291
Pubmed

Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.

CREBBP EP300

2.73e-06258211559821
Pubmed

Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.

CREBBP EP300

2.73e-06258221555743
Pubmed

Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity.

CREBBP HTT

2.73e-06258211264541
Pubmed

CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells.

CREBBP EP300

2.73e-06258212646247
Pubmed

CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.

CREBBP EP300

2.73e-06258232576962
Pubmed

Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.

CREBBP EP300

2.73e-06258219822209
Pubmed

A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.

CREBBP EP300

2.73e-06258224522976
Pubmed

Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice.

CREBBP EP300

2.73e-06258211867645
Pubmed

CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.

CREBBP EP300

2.73e-06258221847097
Pubmed

Expression of the nuclear coactivators CBP and p300 in developing craniofacial tissue.

CREBBP EP300

2.73e-06258211963968
Pubmed

p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.

CREBBP EP300

2.73e-06258234813504
Pubmed

Mutant huntingtin represses CBP, but not p300, by binding and protein degradation.

CREBBP HTT

2.73e-06258215994095
Pubmed

Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300.

CREBBP EP300

2.73e-0625829528808
Pubmed

Analysis of genetic stability at the EP300 and CREBBP loci in a panel of cancer cell lines.

CREBBP EP300

2.73e-06258212696060
Pubmed

Depletion of CBP is directly linked with cellular toxicity caused by mutant huntingtin.

CREBBP HTT

2.73e-06258216766198
Pubmed

Rubinstein-Taybi Syndrome

CREBBP EP300

2.73e-06258220301699
Pubmed

CBP Is Required for Establishing Adaptive Gene Programs in the Adult Mouse Brain.

CREBBP EP300

2.73e-06258236109165
Pubmed

Potential biomarker of metformin action.

CREBBP EP300

2.73e-06258224639469
Pubmed

The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.

CREBBP EP300

2.73e-06258237816914
Pubmed

Retinoids and retinoic acid receptors regulate growth arrest and apoptosis in human mammary epithelial cells and modulate expression of CBP/p300.

CREBBP EP300

2.73e-06258212242694
Pubmed

Binding of p300/CBP co-activators by polyoma large T antigen.

CREBBP EP300

2.73e-06258211438528
Pubmed

Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.

CREBBP EP300

2.73e-06258210918613
Pubmed

CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms.

CREBBP EP300

2.73e-06258231182547
Pubmed

Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.

CREBBP EP300

2.73e-06258235502657
Pubmed

Rubinstein-Taybi syndrome in a Saudi boy with distinct features and variants in both the CREBBP and EP300 genes: a case report.

CREBBP EP300

2.73e-06258230635043
Pubmed

p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.

CREBBP EP300

2.73e-06258231898871
Pubmed

Phenotype and genotype in 52 patients with Rubinstein-Taybi syndrome caused by EP300 mutations.

CREBBP EP300

2.73e-06258227648933
Pubmed

Long-term memory deficits in Huntington's disease are associated with reduced CBP histone acetylase activity.

CREBBP HTT

2.73e-06258222116937
Pubmed

Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.

CREBBP EP300

2.73e-06258230888860
Pubmed

Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.

CREBBP EP300

2.73e-06258227881443
Pubmed

Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.

CREBBP EP300

2.73e-06258219272189
Pubmed

Developmentally regulated expression of the transcriptional cofactors/histone acetyltransferases CBP and p300 during mouse embryogenesis.

CREBBP EP300

2.73e-06258210610021
Pubmed

Emerging roles of p300/CBP in autophagy and autophagy-related human disorders.

CREBBP EP300

2.73e-06258237314181
Pubmed

Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal.

CREBBP EP300

2.73e-06258212397173
Pubmed

CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding.

CREBBP EP300

2.73e-06258215641773
Pubmed

Differential contribution of p300 and CBP to regulatory element acetylation in mESCs.

CREBBP EP300

2.73e-06258232690000
Pubmed

Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 and CREB binding protein.

CREBBP EP300

2.73e-0625829733868
Pubmed

CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.

CREBBP EP300

2.73e-06258230953353
Pubmed

Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.

CREBBP EP300

2.73e-06258221803292
Pubmed

HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter.

CREBBP EP300

2.73e-0625829811832
Pubmed

Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.

CREBBP EP300

2.73e-06258224089570
Pubmed

Early alteration of epigenetic-related transcription in Huntington's disease mouse models.

CREBBP HTT

2.73e-06258229967375
Pubmed

Rubinstein-Taybi syndrome in Chinese population with four novel mutations.

CREBBP EP300

2.73e-06258233063428
Pubmed

EP300/CBP is crucial for cAMP-PKA pathway to alleviate podocyte dedifferentiation via targeting Notch3 signaling.

CREBBP EP300

2.73e-06258234506759
Pubmed

Lack of somatic mutations in the catalytic domains of CREBBP and EP300 genes implies a role for histone deacetylase inhibition in myeloproliferative neoplasms.

CREBBP EP300

2.73e-06258222177454
Pubmed

Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.

CREBBP EP300

2.73e-06258215706485
Pubmed

AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer.

CREBBP EP300

2.73e-06258239266679
Pubmed

A boy with classical Rubinstein-Taybi syndrome but no detectable mutation in the CREBBP and EP300 genes.

CREBBP EP300

2.73e-06258222303793
Pubmed

Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.

CREBBP EP300

2.73e-06258234732714
Pubmed

Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.

CREBBP EP300

2.73e-06258234019788
Pubmed

Genome-wide Analysis of RARβ Transcriptional Targets in Mouse Striatum Links Retinoic Acid Signaling with Huntington's Disease and Other Neurodegenerative Disorders.

GABRG3 SYNPR HTT

3.53e-061858327405468
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

HDAC9 NELL1 RNF123 KANSL2 ZNF423 ARIH2 LRP1 LRP1B CREBBP EP300 RBCK1

7.75e-061285581135914814
Pubmed

Dendrite development regulated by CREST, a calcium-regulated transcriptional activator.

CREBBP EP300

8.19e-06358214716005
Pubmed

The human T-cell leukemia virus type 1 tax protein confers CBP/p300 recruitment and transcriptional activation properties to phosphorylated CREB.

CREBBP EP300

8.19e-06358218070920
Pubmed

The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression.

CREBBP EP300

8.19e-06358221967847
Pubmed

CBP and p300 are essential for renin cell identity and morphological integrity of the kidney.

CREBBP EP300

8.19e-06358219252086
Pubmed

Whole-transcriptome sequencing identifies a distinct subtype of acute lymphoblastic leukemia with predominant genomic abnormalities of EP300 and CREBBP.

CREBBP EP300

8.19e-06358227903646
Pubmed

Inhibition of p300/CBP by early B-cell factor.

CREBBP EP300

8.19e-06358212748286
Pubmed

p300 interacts with the N- and C-terminal part of PPARgamma2 in a ligand-independent and -dependent manner, respectively.

CREBBP EP300

8.19e-06358210075656
Pubmed

Genetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repression.

CREBBP EP300

8.19e-06358224340053
Pubmed

Evolution of antiviral activity in the ribonuclease A gene superfamily: evidence for a specific interaction between eosinophil-derived neurotoxin (EDN/RNase 2) and respiratory syncytial virus.

RNASE2 RNASE6

8.19e-0635829826755
Pubmed

Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response.

CREBBP EP300

8.19e-06358219273602
Pubmed

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila.

CREBBP HTT

8.19e-06358211607033
Pubmed

Activation of Stat3 sequence-specific DNA binding and transcription by p300/CREB-binding protein-mediated acetylation.

CREBBP EP300

8.19e-06358215649887
Pubmed

Expression patterns of histone acetyltransferases p300 and CBP during murine tooth development.

CREBBP EP300

8.19e-06358222179676
Pubmed

CBP/p300 are bimodal regulators of Wnt signaling.

CREBBP EP300

8.19e-06358217410209
Pubmed

DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes.

CREBBP EP300

8.19e-06358226951377
Pubmed

CBP/p300 and SIRT1 are involved in transcriptional regulation of S-phase specific histone genes.

CREBBP EP300

8.19e-06358221789216
Pubmed

Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex.

CREBBP EP300

8.19e-06358212050117
Pubmed

Two transactivation mechanisms cooperate for the bulk of HIF-1-responsive gene expression.

CREBBP EP300

8.19e-06358216237459
Pubmed

A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis.

CREBBP EP300

8.19e-06358212384703
Pubmed

Regulation of transcription factor C/ATF by the cAMP signal activation in hippocampal neurons, and molecular interaction of C/ATF with signal integrator CBP/p300.

CREBBP EP300

8.19e-06358210350644
Pubmed

Loss of p300 and CBP disrupts histone acetylation at the mouse Sry promoter and causes XY gonadal sex reversal.

CREBBP EP300

8.19e-06358229145650
Pubmed

Adenoviral E1A-associated protein p300 as a functional homologue of the transcriptional co-activator CBP.

CREBBP EP300

8.19e-0635827870179
Pubmed

The IFNgamma-induced STAT1-CBP/P300 association, required for a normal response to the cytokine, is disrupted in Brucella-infected macrophages.

CREBBP EP300

8.19e-06358219041714
Pubmed

Normal V(D)J recombination in cells from patients with Nijmegen breakage syndrome.

RNASE2 MLIP

8.19e-06358211282395
Pubmed

Stimulation of c-MYC transcriptional activity and acetylation by recruitment of the cofactor CBP.

CREBBP EP300

8.19e-06358212776737
Pubmed

Convergence of Canonical and Non-Canonical Wnt Signal: Differential Kat3 Coactivator Usage.

CREBBP EP300

8.19e-06358230836930
InteractionZFP41 interactions

FBN2 ARIH2 LRP1 LRP1B

1.52e-0557534int:ZFP41
InteractionHOXB4 interactions

CREBBP TOP3B EP300

2.21e-0521533int:HOXB4
InteractionNCOA6 interactions

ZNF335 CREBBP TOP3B EP300 HTT

3.91e-05145535int:NCOA6
InteractionMAML1 interactions

HDAC9 CREBBP TOP3B EP300

4.06e-0573534int:MAML1
InteractionSLC52A3 interactions

TOP3B HTT

4.06e-054532int:SLC52A3
InteractionLPAR5 interactions

RNF123 TOP3B

6.75e-055532int:LPAR5
InteractionADAMTS20 interactions

ADAMTS20 HTT

6.75e-055532int:ADAMTS20
InteractionMORN1 interactions

TOP3B EP300

6.75e-055532int:MORN1
InteractionNEUROD1 interactions

CREBBP EP300 HTT

8.07e-0532533int:NEUROD1
Cytoband3q23

TRIM42 PXYLP1

1.43e-03445823q23
CytobandEnsembl 112 genes in cytogenetic band chr13q33

TPP2 MYO16

2.23e-0355582chr13q33
CytobandEnsembl 112 genes in cytogenetic band chr3q23

TRIM42 PXYLP1

2.92e-0363582chr3q23
GeneFamilyRibonuclease A family

RNASE2 RNASE6 RNASE8

3.05e-0613413723
GeneFamilyLow density lipoprotein receptors

LRP1 LRP1B

3.85e-0413412634
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

6.68e-0417412486
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

7.50e-041841291
GeneFamilyRing finger proteins

RNF123 TRIM42 RNF183 RBCK1

3.41e-0327541458
GeneFamilyFibronectin type III domain containing

MYLK TRIM42 ANKFN1

5.67e-03160413555
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

TRIM42 CEP192 MYO16

7.96e-03181413694
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

KLF10 ZNF569 ZNF423 ZNF335 ZNF407

2.24e-0271841528
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

GABRG3 NELL1 GPR158 ADAMTS20 UNC13C LRP1B SYNPR

9.44e-10148587d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN2 ZFHX4 ADAMTS20 UNC13C LRP1B MYO16

1.46e-071845862cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN2 ZFHX4 ADAMTS20 UNC13C LRP1B MYO16

1.46e-07184586ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN2 ZFHX4 ADAMTS20 UNC13C LRP1B MYO16

1.46e-071845862b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|COVID-19 / Disease (COVID-19 only), tissue and cell type

GABRG3 NELL1 ADAMTS20 UNC13C LRP1B

1.53e-061505850205318a870e091add66ee4305747dda9f51510d
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

GABRG3 GPR158 ANKFN1 SYNPR MYO16

2.04e-061595855335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KLF10 LRP1 ADAMTS20 GPRC6A LRP1B

4.39e-0618658523b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GABRG3 LIF NELL1 LRP1 MYO16

5.12e-06192585df1545670370fb1010c567cd059c2783eab315f7
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HDAC9 RNASE2 RNASE6 KLF10 LRP1

5.25e-061935856b3a2a32ec6dc96230cee4bbf03932f8a81e6683
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HDAC9 RNASE2 RNASE6 KLF10 LRP1

5.25e-06193585b18c61e360f5f094f260007a56b189e2a48369e4
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

GABRG3 MYLK ZFHX4 ZNF423 UNC13C

5.52e-061955850e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_0|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HDAC9 RNASE2 RNASE6 KLF10 LRP1

5.95e-06198585c1fe38594bd6292fcc60bdbb563376b454731d00
ToppCellTracheal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

NELL1 MYLK PXYLP1 LRP1B STAC

5.95e-06198585cbb63b255bdc92a557c5db1f08f7766ed9346607
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_monocytic|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RNASE2 RNASE6 MIS18BP1 KLF10 LRP1

5.95e-06198585f3346c26b9647a199faf3cd7ab19c3a963dbabc2
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_0|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HDAC9 RNASE2 RNASE6 KLF10 LRP1

5.95e-06198585bfc15de70a7577a2860b53e1e6826a7b5ad23040
ToppCellsevere-cDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

HDAC9 RNASE2 RNASE6 KLF10 LRP1B

6.25e-0620058523e3d2fb86a71f62cca32640842fbba5dd163453
ToppCellCOVID-19-kidney-Epithelial_Doublet|COVID-19 / Disease (COVID-19 only), tissue and cell type

GABRG3 ADAMTS20 UNC13C LRP1B

2.50e-051305841ff28e9d3dc9a791e07d815f8fbb48f75d3f275b
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Pltp|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HDAC9 NELL1 SYNPR STAC

3.25e-051395849e9f29f92dbe65b26cc78b3a1c00778c6a701f5b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

UNC13C PXYLP1 ANKFN1 SYNPR

3.44e-05141584091b5b72811db5fca2314f4a79d467566920e257
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GABRG3 AFM ANKFN1 SYNPR

6.64e-051675843edb0570e583bb527165bcd8a4c25a042054043b
ToppCell(0)_Myeloid-(00)_Monocyte-(000)_CD14+_Monocyte|(00)_Monocyte / immune cells in Peripheral Blood (logTPM normalization)

RNASE2 RNASE6 KLF10 LRP1

6.64e-051675847d9fd6a7a45c2aa0d5f2e3960ca4c97ee8836ba5
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RNASE2 UNC13C SLC13A2 LRRC8D

6.80e-05168584a1755afa2cc50960ba60e07d84d61be429cdea72
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HDAC9 USP30 ADAMTS20 TOP3B

8.14e-0517658427e5115fae5f0f63b333bc99fbf6a6d4c9182c46
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Inner_Medullary_Collecting_Duct_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZFHX4 UNC13C PXYLP1 ANKFN1

8.88e-05180584b927e7380369da6f92ba23d96103519884b70595
ToppCellrenal_papilla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

GABRG3 ZFHX4 UNC13C PXYLP1

8.88e-0518058449829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CACNG5|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HDAC9 UNC13C STAC MYO16

9.67e-05184584658f2e522055e88c92bc482a845c40f8f5f1a8e3
ToppCellControl-Endothelial-Endothelial-Vein|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HDAC9 ZNF423 UNC13C LRP1B

1.01e-0418658492092f11ecce22c14f244e42c499af0822977e6f
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZFHX4 LRP1 ANKFN1 LRP1B

1.01e-041865847582b5154d8e5a4434817b5ab77a10b789ea2288
ToppCell10x5'-blood-Myeloid_Dendritic-DC2|blood / Manually curated celltypes from each tissue

HDAC9 RNASE2 RNASE6 KLF10

1.03e-04187584ab9c9930341527122f26fe5544c5c4818d1fd1b5
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FBN2 ADAMTS20 UNC13C MYO16

1.09e-041905842f54da2bee411f8868348a4c37034184b8f58a89
ToppCellcontrol-Myeloid-CD14_Monocytes_2|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

RNASE2 RNASE6 KLF10 LRP1

1.09e-0419058447513757e0059e8370e49672a577f25ca842e98c
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GABRG3 NELL1 LRP1 MYO16

1.09e-0419058445df8fee00f8949937863159d7aa042e72748d9b
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HDAC9 UNC13C STAC MYO16

1.09e-041905841bbbf0ce222e51f9fd2daca0c18d3965fd4efd31
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NELL1 MYLK LRP1 MYO16

1.12e-04191584b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

NELL1 ZFHX4 LRP1B STAC

1.12e-04191584156b467187331ac6ca390d6ca861d9670bb7b956
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NELL1 MYLK LRP1 MYO16

1.14e-041925846f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MIS18BP1 ZFHX4 ADAMTS20 LRP1B

1.14e-041925848ad6678df89175c5a4a835c8566f1552df3c996e
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NELL1 MYLK LRP1 MYO16

1.14e-04192584162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NELL1 MYLK LRP1 MYO16

1.14e-041925843d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_BHLHE22|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HDAC9 MYLK UNC13C MYO16

1.14e-0419258425460ca9ebd3d49f666394cf99ab77a5e8f77250
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MIS18BP1 ZFHX4 ADAMTS20 LRP1B

1.14e-041925842f5378ea0b2fb2f672a36585d375f675983363a1
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)-D122|Adult / Lineage, Cell type, age group and donor

MIS18BP1 TNFRSF14 LRP1 STAC

1.16e-04193584cc1b6d3bf56e4a88f6fe23dd036a83cf5538c958
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

UNC13C PXYLP1 ANKFN1 LRP1B

1.19e-0419458404bfc555743f7d8821439d05ae442d15e9886c59
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GABRG3 ZFHX4 ZNF423 UNC13C

1.19e-04194584b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NELL1 MYLK LRP1 MYO16

1.19e-041945846e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NELL1 MYLK LRP1 MYO16

1.19e-0419458489b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RNASE2 RNASE6 KLF10 LRP1

1.21e-041955849f7dc9328d244291baf92b03c346c2189b58e7c4
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

GABRG3 MYLK LRP1 UNC13C

1.21e-041955841cdf5f296029ae424d9dba42e86a6d111e4896e6
ToppCellsevere-Classical_Monocyte|World / disease stage, cell group and cell class

RNASE2 RNASE6 KLF10 LRP1

1.21e-04195584cf638aac4d57ae0774008920a1a5e9dfd8c73885
ToppCell343B-Myeloid-Monocyte-CD14+_Monocyte|343B / Donor, Lineage, Cell class and subclass (all cells)

RNASE2 RNASE6 PNPLA8 OXSR1

1.21e-04195584b5ee368c97113432fc8fe742654cd538558f327c
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Monocytic-Classical_Monocyte|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RNASE2 RNASE6 KLF10 LRP1

1.23e-0419658476101d5ebe2a74c0a0a885ec31c3c1847bda8a7b
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_monocytic-classical_monocyte|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RNASE2 RNASE6 KLF10 LRP1

1.23e-0419658428e9e191361966df3a9bd48450090577aa72a999
ToppCellmyeloid-CD14+_Monocyte|World / Lineage and Cell class

RNASE2 RNASE6 KLF10 LRP1

1.23e-04196584b70f9402a1707671c0dd44226fa2adfc4bde8283
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GABRG3 MYLK LRP1 UNC13C

1.23e-041965841450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HDAC9 MYLK GPRC6A LRP1B

1.23e-041965849830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GABRG3 MYLK LRP1 UNC13C

1.26e-0419758431a1852911bda38543916585fda34255fd62a134
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Monocytic-Classical_Monocyte|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RNASE2 RNASE6 KLF10 LRP1

1.26e-041975842afc23f7394d9b40bdf06527c5e6b553e1b02dca
ToppCellPCW_13-14-Mesenchymal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GABRG3 MYLK LRP1 UNC13C

1.26e-0419758473a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCellsevere-Classical_Monocyte|severe / disease stage, cell group and cell class

RNASE2 RNASE6 KLF10 LRP1

1.26e-041975841263f141fd03a9294127ab5572893f7ae8b49230
ToppCellBac-SEP-Myeloid-CD14_Mono|Bac-SEP / Disease, Lineage and Cell Type

RNASE2 RNASE6 KLF10 LRP1

1.26e-04197584d9f1d87ea08139399351db154b63994aa1c9b052
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_monocytic-monocyte|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RNASE2 RNASE6 KLF10 LRP1

1.26e-041975849c8c1ce8ed69b3c2b12ecca349ac1901f66b46ab
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RNASE2 RNASE6 KLF10 LRP1

1.26e-04197584928d70af7b990300be69a4debce6e66b556e5d9f
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid-Monocytic-Classical_Monocyte|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RNASE2 RNASE6 KLF10 LRP1

1.26e-041975840050da0d809075fde3a7f17894dbb410b254988c
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RNASE2 RNASE6 KLF10 LRP1

1.26e-04197584280804810041783f1b7704914b62ffefbb0d88f6
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RNASE2 RNASE6 KLF10 LRP1

1.26e-0419758415bcfe6105c0b508811fb9bba0bc4312fea04f4c
ToppCellPBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_1|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNASE2 RNASE6 KLF10 LRP1

1.28e-0419858403ba8bf87bb2b7aaa560ccca95636cb1d11d5ead
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_monocytic-classical_monocyte|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RNASE2 RNASE6 KLF10 LRP1

1.28e-0419858474591eba5dbb2d77d416309326a26be969e4ad42
ToppCellBLOOD--(3)_Classical_Mono-2| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RNASE2 RNASE6 KLF10 LRP1

1.28e-0419858434c23181c227f65209cde4382248253282f6ac6e
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNASE2 RNASE6 KLF10 LRP1

1.28e-04198584cf0fda1a24449cfd8ed56ffc7841d8accb187949
ToppCellsevere-Myeloid-CD14_Monocytes_3|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

RNASE2 RNASE6 KLF10 LRP1

1.28e-04198584cb8f099cf4ed320615b1c60ddab86b89d8db9a43
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HDAC9 RNASE6 KLF10 LRP1B

1.28e-04198584898ef4f02443780f9b1fc08b73a165fda0ca5cde
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-classical_monocyte-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

RNASE2 RNASE6 KLF10 LRP1

1.28e-04198584c79c1738560d78b63dbed5f2f9621dbc1c2363cb
ToppCellremission-Classical_Monocyte|remission / disease stage, cell group and cell class

RNASE2 RNASE6 KLF10 LRP1

1.28e-04198584d620ea1ee4e1b47a71059695df6c2b4793236ebc
ToppCellPBMC-Convalescent-Myeloid|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNASE2 RNASE6 KLF10 LRP1

1.28e-041985843973bbc1bfb5b08dd1becd5e4bb5899b15df9e55
ToppCellCOVID-19_Convalescent-Myeloid-Classical_Monocyte|COVID-19_Convalescent / Disease group, lineage and cell class

RNASE2 RNASE6 KLF10 LRP1

1.28e-04198584ca58c62d7f732631af1f7cabaa785757d031c011
ToppCellPBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_1|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RNASE2 RNASE6 KLF10 LRP1

1.28e-041985841b14f7eaf3e2805ca9efbebad4e670329db74dc9
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-classical_monocyte|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

RNASE2 RNASE6 KLF10 LRP1

1.28e-041985841d1c80569f1e307285ba0ebaf5c72e0b5b538864
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid-Monocytic|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RNASE2 RNASE6 KLF10 LRP1

1.28e-041985844d70995b4dd6365b0c3cda3663a82efdb4870d19
ToppCellsevere-Myeloid-CD14_Monocytes_3|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

RNASE2 RNASE6 KLF10 LRP1

1.28e-04198584374d7a24e00cd3f435ca980123ab3c6a441c9ad5
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNASE2 RNASE6 KLF10 LRP1

1.28e-041985847e1f08dae11a7cc7949a5622d82c7e6660d06dea
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RNASE2 RNASE6 KLF10 LRP1

1.28e-04198584525adc91fd8f2ad957b1879a5bf3950baa7d5ef8
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Dendritic-conventional_dendritic_cell|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HDAC9 RNASE6 KLF10 LRP1B

1.28e-0419858442be18aef4f656a86c61630b061826a858c496fd
ToppCellMultiple_Sclerosis-Myeloid-cDC|Multiple_Sclerosis / Disease, Lineage and Cell Type

HDAC9 RNASE2 RNASE6 LRP1B

1.28e-04198584ac139bfbf52b2feddb0c05b0708c8c9efbe119c9
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

RNASE2 RNASE6 KLF10 LRP1

1.28e-0419858494e2567f057b2c455a9656b121321a28e7cb1d2b
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RNASE2 RNASE6 KLF10 LRP1

1.28e-0419858470e62d815b2a0aa5327ff94d6f4d503176e007b9
ToppCellPBMC-Convalescent-Myeloid-Classical_Monocyte|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

RNASE2 RNASE6 KLF10 LRP1

1.28e-04198584708f9644362d300ecc477d76208e4957bb92487e
ToppCellCOVID-19_Severe-Myeloid-Classical_Monocyte|COVID-19_Severe / Disease group, lineage and cell class

RNASE2 RNASE6 KLF10 LRP1

1.28e-04198584dfe92577c7d1e63315c7564d5d99362c6e7d4d46
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RNASE2 RNASE6 KLF10 LRP1

1.28e-041985842a361af16bf6ecec12f22bdf7926afc7e5ad45ae
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

RNASE2 RNASE6 KLF10 LRP1

1.28e-041985840128d00e6c3f99a026329dd169c0ea5e0e24c59c
ToppCellCOVID-19_Convalescent-Myeloid|COVID-19_Convalescent / Disease group, lineage and cell class

RNASE2 RNASE6 KLF10 LRP1

1.28e-0419858420016bfa7e651f3d22d6148469737b50369c149b
ToppCellPBMC-Convalescent-Myeloid-Classical_Monocyte|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNASE2 RNASE6 KLF10 LRP1

1.28e-04198584e2ead6886548638f94e9302b8eb8d797ce454d41
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_monocytic|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RNASE2 RNASE6 KLF10 LRP1

1.28e-041985843e1e79bb7b13540a06956b59c6a62984efea19ee
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNASE2 RNASE6 KLF10 LRP1

1.28e-0419858451c220507bb05aa6338fec494b8ecf4902437708
ToppCellPBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

RNASE2 RNASE6 KLF10 LRP1

1.28e-04198584711618d47281c07e89723482c28570449eb7c626
ToppCellPBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNASE2 RNASE6 KLF10 LRP1

1.28e-04198584abfef06ce9e400094de4e3fd809b09f83ad02db5
ToppCellPBMC-Convalescent-Myeloid|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

RNASE2 RNASE6 KLF10 LRP1

1.28e-041985847e348a21c0ad6e15b4d2a58810428ab28ff8ff47
ToppCellmild-HLA-DR-_S100A+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

RNASE2 RNASE6 KLF10 LRP1

1.31e-04199584d0d286eafe935f9b3aaba5b783e8911251121b4a
ToppCellPBMC-Mild-Myeloid|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

RNASE2 RNASE6 KLF10 LRP1

1.31e-0419958402256d86541be6851634283047fdc05fdf095114
ToppCellIIF-Myeloid-CD14_Mono|IIF / Disease, Lineage and Cell Type

RNASE2 RNASE6 KLF10 LRP1

1.31e-04199584accfb3d8ad3f03f9302f2056ca16c1be6231a351
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_monocytic|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RNASE2 RNASE6 KLF10 LRP1

1.31e-041995847dde5c02fcae64cd2d68f607500f2a46b97851fd
DiseaseMenke-Hennekam syndrome

CREBBP EP300

3.41e-062552cv:C5681632
DiseaseRubinstein-Taybi syndrome (implicated_via_orthology)

CREBBP EP300

3.41e-062552DOID:1933 (implicated_via_orthology)
DiseaseRubinstein-Taybi syndrome

CREBBP EP300

3.41e-062552cv:C0035934
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

3.41e-062552C4551859
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

3.41e-062552180849
DiseaseRubinstein-Taybi syndrome due to CREBBP mutations

CREBBP EP300

3.41e-062552cv:C4551859
DiseaseRubinstein-Taybi syndrome (is_implicated_in)

CREBBP EP300

3.41e-062552DOID:1933 (is_implicated_in)
DiseaseRubinstein-Taybi Syndrome

CREBBP EP300

3.41e-062552C0035934
Diseaseobsolete_red blood cell distribution width

TPP2 RNF123 FBN2 GPR158 LYPD5 LRRC37A2 ZNF407 OXSR1 LRRC37B EP300 MYO16

3.23e-0513475511EFO_0005192
Diseaseepilepsy (implicated_via_orthology)

LRP1 UNC13C SLC13A2 LRP1B

2.46e-04163554DOID:1826 (implicated_via_orthology)
Diseasecentral corneal thickness

FBN2 GPR158 ADAMTS20 ZNF407 RNF183

2.76e-04309555EFO_0005213
Diseasesynophrys measurement

HDAC9 ZFHX4 HTT

2.82e-0468553EFO_0007906
Diseasemigraine disorder

NELL1 FBN2 KLF10 LRP1 HMGXB3

5.34e-04357555MONDO_0005277
DiseaseLymphoma, Follicular

TNFRSF14 CREBBP

6.34e-0420552C0024301
Diseasecortical thickness

HDAC9 NELL1 FBN2 ZNF423 LRP1 ADAMTS20 ANKFN1 MYO16

1.01e-031113558EFO_0004840
DiseaseMental Depression

HDAC9 LIF RNF123 HTT

1.30e-03254554C0011570
Diseasewhite matter volume measurement

GPR158 LRP1B

1.63e-0332552EFO_0008320
Diseaseceliac disease

ZNF335 ANKFN1 STAC

1.70e-03126553EFO_0001060
Diseaselysophosphatidylethanolamine 18:1 measurement

UNC13C LRP1B

1.84e-0334552EFO_0010368
Diseasewaist-hip ratio

NELL1 RNF123 MLIP ZNF423 ADAMTS20 ZNF407 CEP192 HTT

1.86e-031226558EFO_0004343
DiseaseDepressive disorder

HDAC9 LIF RNF123 HTT

2.08e-03289554C0011581
DiseaseAlzheimer disease

GABRG3 ADAMTS20 SYNPR MYO16 RBCK1

2.08e-03485555MONDO_0004975
Diseasebody weight

GABRG3 NELL1 FBN2 MLIP ZNF423 PXYLP1 CEP192 LRP1B

2.22e-031261558EFO_0004338
DiseaseMoyamoya disease

HDAC9 LRP1

2.54e-0340552MONDO_0016820
DiseaseCarcinoma, Transitional Cell

CREBBP EP300

2.67e-0341552C0007138
Diseaseasthma

HDAC9 TNFRSF14 LRP1 UNC13C LRP1B STAC

2.68e-03751556MONDO_0004979
Diseaseserum IgG glycosylation measurement

GPR158 ZNF423 ZNF407 ANKFN1 LRP1B

2.88e-03523555EFO_0005193
Diseasecortical surface area measurement

HDAC9 NELL1 FBN2 ZNF423 ADAMTS20 ANKFN1 LIN28A MYO16

3.30e-031345558EFO_0010736
Diseasenose morphology measurement

HDAC9 GABRG3 TRIM42 ZNF407

3.31e-03329554EFO_0007843
Diseaseneuroimaging measurement

HDAC9 NELL1 FBN2 ADAMTS20 ANKFN1 MYO16 HTT

3.58e-031069557EFO_0004346

Protein segments in the cluster

PeptideGeneStartEntry
SACKQPSNKCMAIHS

SYNPR

156

Q8TBG9
LNHMTHCQSGKSCQV

EP300

376

Q09472
MEGLPQKHNFSHCCS

AFM

101

P43652
SCLKGVHLCQVLMNH

DEPDC4

116

Q8N2C3
VLNHMTHCQAGKACQ

CREBBP

391

Q92793
PHHCAVCMQFVRKEN

ARIH2

136

O95376
VNKPPSVIQCHMHAC

ADAMTS20

1401

P59510
LLSHNACNKLSHPMV

MLIP

431

Q5VWP3
LKEIQAMSQCHHPNI

OXSR1

61

O95747
PSHMACCLCQFKNSI

LRRC37A3

1021

O60309
SIMNCLHHPKLVQCV

MYLK

1511

Q15746
INHNRSAACACPHLM

LRP1B

1546

Q9NZR2
PTKNLCHMDCHDLLN

SPACA5

91

Q96QH8
ELNMCHSNCQNKPTL

MIS18BP1

546

Q6P0N0
PSHMACCLCQFKNSI

LRRC37A2

1021

A6NM11
PSHMACCLCQFKNSI

LRRC37A

1021

A6NMS7
MHQANPHLVNCNEEK

MYO16

276

Q9Y6X6
GTHKCHLNNSECMPI

GPR158

326

Q5T848
HVNCLLCKAIHEQMN

RBCK1

396

Q9BYM8
NATCAIRHPCHNNLM

LIF

31

P15018
VSCACPHLMKLHKDN

LRP1

1561

Q07954
APKNPHCTSQEHKCN

LRP1

2891

Q07954
VTAQVKMCLNPHCLA

HMGXB3

781

Q12766
HTQCLMQHEPCGKAQ

FAM205A

546

Q6ZU69
HTQCLMQHEPCGKAQ

FAM205BP

276

Q63HN1
PSHMACCLCQFKNSI

LRRC37B

711

Q96QE4
KMHYCHANTVCVNLP

NELL1

441

Q92832
QTDMPHCLLCNNKTH

GPRC6A

556

Q5T6X5
QAHLLKNMSHCRQPS

HTT

626

P42858
CQLQLHNFPMDEHSC

GABRG3

171

Q99928
DKCNAHLMTHDALPN

LYPD5

106

Q6UWN5
CPHQNKTVLHMDGCL

CEP192

396

Q8TEP8
CSNQSLPMTRHCLTH

KANSL2

311

Q9H9L4
DAQLCNHQTCPMKAA

KLF10

161

Q13118
SMKQVHQCIERCHVP

FAM136A

46

Q96C01
MLKHQCVCGNSTTHP

HDAC9

641

Q9UKV0
HNCDMHASCLNIPGS

FBN2

1376

P35556
SQKHLHLTQCMSLCV

SLC13A2

211

Q13183
QMTNLQELHLCHCPA

LRRC8D

511

Q7L1W4
LLNNPSALAMHECKC

PNPLA8

631

Q9NP80
ANSHLVNHLNCPMCS

TRIM42

136

Q8IWZ5
NNTFHTPKMLDCCHS

RNF183

21

Q96D59
QELHHDMPLQCLSSK

PRR32

26

B1ATL7
AANPIDSMLCHFCHN

PXYLP1

291

Q8TE99
NCHQSSKPVNMTDCR

RNASE6

91

Q93091
NMTCPSNKTRKNCHH

RNASE2

86

P10153
MQNLHLCQSKKHSAP

ANKFN1

76

Q8N957
CNECTHPSCQHSLSM

TOP3B

706

O95985
ICCPLCQDVLSNKMH

ZFHX4

1201

Q86UP3
SHCDKENVPCILMNN

UNC13C

1786

Q8NB66
NSCKNCHQSHGPMSL

RNASE8

91

Q8TDE3
HKSCKACINQHLMNN

RNF123

1271

Q5XPI4
CDVCNHMIVGTNAKH

STAC

121

Q99469
QCPSHLELMNQCRHI

TPP2

581

P29144
LEHNFDCHNNVKCLM

ZNF569

146

Q5MCW4
HLNGLSKCLQCQMCD

TNFRSF14

86

Q92956
NMVCKHCEHQSPVRF

USP30

231

Q70CQ3
KPQQSHTCQICLDSM

ZNF423

436

Q2M1K9
INHECKLCNQMFDSP

ZNF423

1196

Q2M1K9
ESHMQQPKEHTCCHC

ZNF407

206

Q9C0G0
MAQHSSLRPHQCSQC

ZNF335

1066

Q9H4Z2
PQPKKCHFCQSISHM

LIN28A

156

Q9H9Z2