Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpurine nucleotide transmembrane transporter activity

SLC19A1 ABCC4 SLC35B1

1.24e-0629153GO:0015216
GeneOntologyMolecularFunctionnucleotide transmembrane transporter activity

SLC19A1 ABCC4 SLC35B1

1.85e-0633153GO:0015215
GeneOntologyMolecularFunctionorganophosphate ester transmembrane transporter activity

SLC19A1 ABCC4 SLC35B1

3.08e-0639153GO:0015605
GeneOntologyMolecularFunctionguanine nucleotide transmembrane transporter activity

SLC19A1 ABCC4

5.26e-065152GO:0001409
GeneOntologyMolecularFunctionnucleobase-containing compound transmembrane transporter activity

SLC19A1 ABCC4 SLC35B1

1.09e-0559153GO:0015932
GeneOntologyMolecularFunctionpurine ribonucleotide transmembrane transporter activity

SLC19A1 SLC35B1

1.32e-0423152GO:0005346
GeneOntologyMolecularFunctionadenine nucleotide transmembrane transporter activity

SLC19A1 SLC35B1

1.69e-0426152GO:0000295
GeneOntologyMolecularFunctionmodified amino acid transmembrane transporter activity

SLC19A1 ABCC4

2.74e-0433152GO:0072349
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

SLC19A1 ABCC4

2.91e-0434152GO:0042910
GeneOntologyMolecularFunctionamide transmembrane transporter activity

SLC19A1 ABCC4

4.46e-0442152GO:0042887
GeneOntologyMolecularFunctioncarbohydrate derivative transmembrane transporter activity

SLC19A1 SLC35B1

8.79e-0459152GO:1901505
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC19A1 ABCC4 SLC35B1

1.25e-03293153GO:0008514
GeneOntologyMolecularFunctionantiporter activity

SLC19A1 SLC35B1

4.69e-03138152GO:0015297
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC19A1 ABCC4 SLC35B1

4.98e-03477153GO:0022804
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC19A1 NIPAL4 ABCC4 SLC35B1

9.80e-031180154GO:0022857
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC19A1 ABCC4

1.03e-02207152GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC19A1 ABCC4

1.04e-02208152GO:0005342
GeneOntologyMolecularFunctiontransporter activity

SLC19A1 NIPAL4 ABCC4 SLC35B1

1.33e-021289154GO:0005215
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC19A1 SLC35B1

2.02e-02296152GO:0015291
GeneOntologyMolecularFunctionamide binding

FZD4 SLC19A1

2.06e-02299152GO:0033218
GeneOntologyBiologicalProcesspurine ribonucleotide transport

SLC19A1 ABCC4 SLC35B1

3.02e-0640153GO:0015868
GeneOntologyBiologicalProcessadenine nucleotide transport

SLC19A1 ABCC4 SLC35B1

3.51e-0642153GO:0051503
GeneOntologyBiologicalProcesspurine nucleotide transport

SLC19A1 ABCC4 SLC35B1

4.05e-0644153GO:0015865
GeneOntologyBiologicalProcessnucleotide transport

SLC19A1 ABCC4 SLC35B1

5.97e-0650153GO:0006862
GeneOntologyBiologicalProcessguanine nucleotide transmembrane transport

SLC19A1 ABCC4

2.21e-0510152GO:1903790
GeneOntologyBiologicalProcesscyclic nucleotide transport

SLC19A1 ABCC4

2.70e-0511152GO:0070729
GeneOntologyBiologicalProcessguanine nucleotide transport

SLC19A1 ABCC4

2.70e-0511152GO:0001408
GeneOntologyBiologicalProcesscarbohydrate derivative transport

SLC19A1 ABCC4 SLC35B1

4.27e-0596153GO:1901264
GeneOntologyBiologicalProcessxenobiotic transmembrane transport

SLC19A1 ABCC4

8.38e-0519152GO:0006855
GeneOntologyBiologicalProcessorganophosphate ester transport

SLC19A1 ABCC4 SLC35B1

2.02e-04162153GO:0015748
GeneOntologyBiologicalProcessnucleotide transmembrane transport

SLC19A1 ABCC4

2.27e-0431152GO:1901679
GeneOntologyBiologicalProcesspurine-containing compound transmembrane transport

SLC19A1 ABCC4

3.79e-0440152GO:0072530
GeneOntologyBiologicalProcessmodified amino acid transport

SLC19A1 ABCC4

4.59e-0444152GO:0072337
GeneOntologyBiologicalProcessnucleobase-containing compound transport

SLC19A1 ABCC4 SLC35B1

7.10e-04249153GO:0015931
GeneOntologyBiologicalProcesslipid export from cell

FZD4 ABCC4

9.70e-0464152GO:0140353
GeneOntologyBiologicalProcessxenobiotic transport

SLC19A1 ABCC4

9.70e-0464152GO:0042908
GeneOntologyBiologicalProcesstransport across blood-brain barrier

SLC19A1 ABCC4

1.78e-0387152GO:0150104
GeneOntologyBiologicalProcessvascular transport

SLC19A1 ABCC4

1.82e-0388152GO:0010232
Pubmed

Chromosomal localization, hematologic characterization, and iron metabolism of the hereditary erythroblastic anemia (hea) mutant mouse.

PIGF GPI

6.24e-06915215155459
Pubmed

LC-MS/MS Based Quantitation of ABC and SLC Transporter Proteins in Plasma Membranes of Cultured Primary Human Retinal Pigment Epithelium Cells and Immortalized ARPE19 Cell Line.

SLC19A1 ABCC4

1.82e-051515228112518
Pubmed

Quantitative Protein Expression in the Human Retinal Pigment Epithelium: Comparison Between Apical and Basolateral Plasma Membranes With Emphasis on Transporters.

SLC19A1 ABCC4

2.65e-051815231791063
Pubmed

Quantitative targeted absolute proteomic analysis of transporters, receptors and junction proteins for validation of human cerebral microvascular endothelial cell line hCMEC/D3 as a human blood-brain barrier model.

SLC19A1 ABCC4

3.63e-052115223137377
GeneFamilySolute carriers

SLC19A1 SLC35B1

2.30e-02395112752
CoexpressionLIU_PROSTATE_CANCER_UP

SLC19A1 TMEM161A ABCC4

2.30e-0599153M4619
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Granulocytic-Neutrophil|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMXL2 CPN2 GRINA

2.42e-05172153c32e6af9e2d29da47b5d870207b598cff11aef6c
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Granulocytic|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMXL2 CPN2 GRINA

2.42e-051721531a0556c97fcba126126c22adea5235d977d41ebe
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DMXL2 TMED5 GRINA

3.67e-0519815393cc01d91ffc543fd1a717ef47e02e532b50b665
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte-Mono_c1-CD14-CCL3|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FZD4 GRINA

7.36e-04121152b6dada0712b1f9793bc61e54ec7f10c9eaf53b86
ToppCellMyeloid-F|World / shred on cell class and cell subclass (v4)

PTBP3 GRINA

1.19e-031541526d53eec4aefe54836bbfd314f28f5e9a24c2d833
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTBP3 ABCC4

1.25e-03158152debebc8534a80e5500051f6fd352dc201585968d
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMXL2 GRINA

1.25e-03158152d43b335e6aa12d84a75b988fbd6127ff1f4af25c
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMXL2 GRINA

1.25e-03158152ab12b29ce51ca2fcac469cc932391217d97145f9
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Myeloid-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMXL2 GRINA

1.26e-03159152a6093b230afdd4d91870d289c6ac91d1856666a3
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PIGF ABCC4

1.26e-03159152f7bccfeffa737f151417bf52ea45111b0957bce9
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMXL2 GRINA

1.30e-03161152e227f7b711475624cf80e77f235b1783d88d57b4
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMXL2 GRINA

1.30e-031611528280a029026c272cae9649b27575831b0dd4e242
ToppCellfacs-Lung-18m-Hematologic-myeloid-neutrophil|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DMXL2 GRINA

1.31e-03162152ad974426039f4952c59d27167eac24dc6ce63f5e
ToppCellfacs-Lung-18m-Hematologic-myeloid-neutrophil-neutrophil|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DMXL2 GRINA

1.31e-031621524e7e565091bce227d794a36af2e5dfc4a791efad
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTBP3 ABCC4

1.34e-0316415283141be8dfed85511ea6afda7c76ff4b6b5ef021
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3|Striatum / BrainAtlas - Mouse McCarroll V32

FZD4 SLC19A1

1.34e-03164152e24b06a14565f7798ac50c2fe3f34d4547b9000e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTBP3 ABCC4

1.39e-03167152edc5f04584b44f99ff9a62bbe0dab6fc044fb334
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMEM69 ABCC4

1.41e-0316815255c9de7b3a1d6cf7b02b020ff92ab4ede8d195cc
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMXL2 GRINA

1.43e-03169152e0076aa61b4ef3f836f5750005d0469d3982eb6d
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMXL2 GRINA

1.43e-03169152a5964aef04093b460bbe29d5e2e7389f8fd2d46f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTBP3 ABCC4

1.43e-03169152a4fd646b9bf87225131fca530bd6b52df9eaf489
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTBP3 ABCC4

1.43e-031691524b3a7b4a497178799b6b2f0b744f5fb752cee31a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTBP3 ABCC4

1.43e-031691522a21f2cef959526bfe3c8f081f4f7e9dd4e01a37
ToppCellfacs-BAT-Fat-18m-Myeloid-granulocyte|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMXL2 GRINA

1.43e-03169152d3e6c75e5eda133fb6535cfe6c6a1026641f26ac
ToppCellfacs-BAT-Fat-3m-Myeloid-granulocyte|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMXL2 GRINA

1.44e-031701528fd0a55266066a51266ab616c38c883e2680bcf4
ToppCellfacs-BAT-Fat-24m-Myeloid-granulocyte|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMXL2 GRINA

1.44e-0317015253916d85f0d6c7e5ef3d900d6ead946f75e32567
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMXL2 GRINA

1.46e-03171152ab21f20ec041cbaacccbd7da4dccdb77ec8bc5c6
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMXL2 GRINA

1.46e-0317115297ad2cfff568a9d006ab1d2e6e00946ee4e3beb3
ToppCell10x5'-Liver-Myeloid_Mac-Intermediate_macrophages|Liver / Manually curated celltypes from each tissue

DMXL2 GRINA

1.46e-0317115225e0333743affdb662223fb5220b8a61fa02ad9f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTBP3 ABCC4

1.49e-031731520bc2aacae60c6d3276b0949eb0748b4ac1f56e54
ToppCell10x5'-bone_marrow-Myeloid_Mac-Intermediate_macrophages|bone_marrow / Manually curated celltypes from each tissue

DMXL2 GRINA

1.51e-03174152268abfc4d53a3ba3931dbcafffef09a72ea0edfa
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTBP3 ABCC4

1.51e-031741525f4436863a40f8bca46e2989bca66c02b6be88d4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTBP3 ABCC4

1.55e-0317615225ebc8716aa44e44fce577701e3e82c6745a75ab
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTBP3 ABCC4

1.55e-03176152cb21342dd135cc80a50aafe7bf8bf31265db68dd
ToppCellmetastatic_Brain-T/NK_cells-Exhausted_Tfh|T/NK_cells / Location, Cell class and cell subclass

SLC19A1 NIPAL4

1.58e-031781529a3581a0158dfa5a1cc942f8c532afb5e38b272a
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD4 NIPAL4

1.58e-031781526d9ecfaeb50d562899380de379ebf7b99fd8adc9
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD4 NIPAL4

1.58e-03178152d3f518cd75b02e85d45cbb9b2eff30f0272512a8
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC19A1 NIPAL4

1.60e-03179152bfc226bcf0b93525992344f968268a261d86fcbf
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC19A1 NIPAL4

1.60e-0317915236ad18f52e175ab636ceaa3be81212fa362c96c1
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NIPAL4 ABCC4

1.60e-03179152a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCellfacs-Skin-Anagen-3m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NIPAL4 ABCC4

1.60e-031791524a072526c3a524a7aed99bdb32a07a1ce1f48972
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMXL2 TMEM69

1.62e-0318015212f3c4c4aa7fe03c0ef847bd4d4942c808015f5f
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMXL2 TMEM69

1.62e-031801522a28fbfe10a340c8662c2c8be33792f41fc09088
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMXL2 TMEM69

1.62e-031801521bc01bb76d0d3f8db74f9244436d3e6d6015ed5d
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DMXL2 GRINA

1.65e-031821524234d0cc57b5266a5e03133c75c7918abe48465e
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PTBP3 DMXL2

1.65e-0318215221dcab170ffeef89faa9fee5008568cb6e15c694
ToppCellCV-Severe-4|CV / Virus stimulation, Condition and Cluster

GPI NIPAL4

1.65e-03182152c19bbc43d97c426aec37414f46f667a19b62a257
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DMXL2 GRINA

1.67e-03183152fcb0f755382d88fb207fc2322cd224c09c6e2ea6
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NIPAL4 TMEM69

1.67e-031831520e8fb371d8eac777451c76f41d53577f5dfb740d
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NIPAL4 TMEM69

1.67e-03183152cbc3b00faa7e4e0dbbbc8ee105467c65241c7470
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DMXL2 GRINA

1.67e-031831524763df29c888d47c22076803b054f06b4cc29368
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DMXL2 GRINA

1.69e-03184152857ca1fc4de07b300839b22924211dc624453841
ToppCellCV-Moderate-4|CV / Virus stimulation, Condition and Cluster

GPI NIPAL4

1.69e-0318415290f5b447064743246b09a6c47bf561efafa15e1f
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PTBP3 DMXL2

1.69e-031841528e5fc2bdd3071e782aa8c56b8a39f8ea8f03f623
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DMXL2 GRINA

1.69e-03184152bc0dfe29337f02594e7e0092c9e47dda94b45ad5
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DMXL2 TMED5

1.69e-03184152e343dd7777a29048e3f12a939f7f782b8b7b4fea
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PTBP3 DMXL2

1.69e-03184152fe9ea4d0e0be820e95eaf9bb42a5560d0e177574
ToppCelldroplet-Lung-LUNG-1m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTBP3 DMXL2

1.70e-0318515253a5218c1e6eb12daccde3d6e02f337e2586d74c
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

DMXL2 ABCC4

1.70e-03185152a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellCV-Moderate-4|Moderate / Virus stimulation, Condition and Cluster

GPI NIPAL4

1.70e-031851524a3ce0c603c2ffe11f0f00775b6af4f6d9a6070a
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

DMXL2 ABCC4

1.72e-031861528571956890fc9894d766ba294a28e376b4aba428
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PTBP3 DMXL2

1.72e-031861527950e03ea080238c168b9d807e217f459acdfb28
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PTBP3 ABCC4

1.76e-03188152e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DMXL2 GRINA

1.80e-0319015218c020ca9a23399214133ec255ab870e0060f2e1
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Macrophage|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMXL2 GRINA

1.80e-03190152e1c02fe6fa43a36381cb9f02569fa9b1c5f5efdc
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMXL2 GRINA

1.80e-031901526de15ec88426fbf52acb0a8371f82cf03b6a6237
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Monocytic-Classical_Monocyte-Mono_c1-CD14-CCL3|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMXL2 GRINA

1.80e-03190152212f0d9defcc3174e225cc3d90e7814e238794b6
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_monocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DMXL2 GRINA

1.80e-0319015200ef6ec71353e42260c0d807d7da65b63154c288
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMXL2 GRINA

1.82e-0319115281f77bf497b8e0ae0affe7d5f4f00446547229f6
ToppCell5'|World / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GPI GRINA

1.82e-031911520e752756e9d1b444930522efc0fdca072d42535f
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD4 ABCC4

1.83e-03192152a116db7dec495e5a0ba9c7537057cd1e567d7885
ToppCell(1)_Control_(PBS)-(1)_VE-Cad+_vascular_cells|(1)_Control_(PBS) / Stress and Cell class

FZD4 PTBP3

1.83e-03192152e16e49b302019474232ef4cc0ff217d33afe34cf
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD4 ABCC4

1.83e-031921529ae05db5bfb8b9d3935c0328e6f2d489d2b1ebfd
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD4 ABCC4

1.83e-0319215266defad13bd8e79319741e43ddb056841710b1d7
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DMXL2 GRINA

1.83e-031921520219093e7921a0db78053aee13ec480b520f5662
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTBP3 TMED5

1.83e-03192152d5ec4cdb15620a5abfc83577353501186c2bc86a
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DMXL2 GRINA

1.83e-03192152f14ee74ac3275601749a23c5efe39c2413a62e1a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMXL2 GRINA

1.85e-0319315245205ad1ef12aabf33059a7ff922a3bb86994c2f
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DMXL2 GRINA

1.85e-031931525f732598cdb6f3bd519f044a9cc553bd2e8b1052
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DMXL2 GRINA

1.85e-031931521db487e5f81849740d57cc3e2b5739e8f7581efb
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMXL2 GRINA

1.85e-031931521beca3d3b34082b7d9112fbd094bee8019921ca0
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMXL2 GRINA

1.85e-031931522ebb950476767f330241b0077ced22e55e124359
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)-D122|Adult / Lineage, Cell type, age group and donor

DMXL2 GRINA

1.85e-03193152cc1b6d3bf56e4a88f6fe23dd036a83cf5538c958
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTBP3 TMED5

1.85e-031931525da60321bcf761913eb30779b6d8b1e933c5e51e
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Monocytic-Classical_Monocyte-Mono_c1-CD14-CCL3|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMXL2 GRINA

1.85e-0319315269352551ad5db325ac0d6df2ac1e35ae473ac01f
ToppCellLeuk-UTI-Myeloid-CD14_Mono|Leuk-UTI / Disease, Lineage and Cell Type

DMXL2 GRINA

1.85e-03193152d1eac8627d00629ed2e81d3b86778007304efcb7
ToppCell(4)_Endothelial_cells-(42)_EC-sinusoidal|World / Cell class and subclass of bone marrow stroma cells in homeostatis

FZD4 PTBP3

1.87e-031941524428b472c2042f88eae028b1770767512a515b75
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTBP3 TMED5

1.87e-03194152be869e186386d03ebb670971dd24fa656b4b0edf
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)|Children_(3_yrs) / Lineage, Cell type, age group and donor

DMXL2 GRINA

1.87e-0319415269cf7c989ac355c459db13f9d4267b55adc3c174
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DMXL2 GRINA

1.87e-031941523ef9e88e66f2f2ae95dcc834ea605c40c60783fc
ToppCell5'|World / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPI GRINA

1.87e-031941527f98f8bfd17a762a2bf748f1c689c7e941793917
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DMXL2 GRINA

1.87e-03194152a94f9f7179a5733e3c378ff8b337e288785433a1
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTBP3 TMED5

1.87e-031941524d6c9b016e3a0641954a8ea10c97d1cd76fadd9f
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage|367C / Donor, Lineage, Cell class and subclass (all cells)

TMED5 GRINA

1.87e-0319415240c91ed945bd5990a0dbf2090d37a660b19aaab2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c06-MKI67|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PIGF SLC19A1

1.87e-031941525771a28a61f4d9b5479891f3224909ab003cb241
ToppCellControl-Myeloid|Control / Disease state, Lineage and Cell class

DMXL2 GRINA

1.89e-0319515246ce2e403ca5d757e5ba17349b6c7ce5cde1f195
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-myeloid|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DMXL2 GRINA

1.89e-03195152b0dbaae86f5703ab62f925e0f36500274044884a
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DMXL2 GRINA

1.89e-031951520110b976f98561ecd2e20ff6e7e3960a401bb7c2
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)|Adult / Lineage, Cell type, age group and donor

DMXL2 GRINA

1.89e-0319515255e25f702af19146a161861cfd15f40bbda1dc35
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMXL2 GRINA

1.89e-031951529f7dc9328d244291baf92b03c346c2189b58e7c4
DrugNaringin hydrate [11032-30-7]; Up 200; 6.6uM; MCF7; HT_HG-U133A

PTBP3 SLC19A1 DMXL2 GRINA

5.19e-061981443286_UP
DrugDisopyramide [3737-09-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A

SLC19A1 DMXL2 TMEM161A ABCC4

5.29e-061991447439_UP
DrugBumetanide

SLC19A1 ABCC4

4.19e-0516142ctd:D002034
Drug6-thioguanine

PIGF SLC19A1 ABCC4

6.32e-05130143CID002723601
DrugD-G-G

GPI GRINA

8.82e-0523142CID000444866
Drughypoiodite

GPI SLC19A1

1.32e-0428142CID000123340
Drugedatrexate

SLC19A1 ABCC4

1.51e-0430142CID000054586
DrugICI 182,780; Down 200; 1uM; MCF7; HT_HG-U133A

SLC19A1 TMEM161A ABCC4

1.80e-041851436965_DN
DrugCyclobenzaprine hydrochloride [6202-23-9]; Up 200; 12.8uM; HL60; HT_HG-U133A

SLC19A1 DMXL2 TMEM161A

2.01e-041921431332_UP
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HG-U133A

SLC19A1 TMEM161A ABCC4

2.01e-041921431400_DN
DrugMephentermine hemisulfate [1212-72-2]; Down 200; 9.4uM; HL60; HT_HG-U133A

PTBP3 SLC19A1 DMXL2

2.04e-041931432563_DN
DrugRapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A

PTBP3 SLC19A1 ABCC4

2.04e-041931436967_DN
DrugM-NR

GPI SLC19A1

2.07e-0435142CID003000480
DrugHesperetin [520-33-2]; Down 200; 13.2uM; PC3; HG-U133A

FZD4 SLC19A1 DMXL2

2.07e-041941431947_DN
DrugTrichlorfon [52-68-6]; Down 200; 15.6uM; MCF7; HT_HG-U133A

PTBP3 SLC19A1 TMEM161A

2.07e-041941431675_DN
DrugIndapamide [26807-65-8]; Down 200; 10.6uM; HL60; HT_HG-U133A

PTBP3 TMEM161A GRINA

2.13e-041961432361_DN
DrugTorsemide [56211-40-6]; Down 200; 11.4uM; MCF7; HT_HG-U133A

SLC19A1 TMEM161A ABCC4

2.13e-041961433517_DN
DrugJosamycin [16846-24-5]; Down 200; 4.8uM; MCF7; HT_HG-U133A

SLC19A1 TMEM161A ABCC4

2.16e-041971435692_DN
DrugLeucomisine [17946-87-1]; Down 200; 16.2uM; HL60; HT_HG-U133A

PTBP3 SLC19A1 TMEM161A

2.16e-041971436125_DN
Drugprochlorperazine dimaleate salt; Down 200; 10uM; MCF7; HT_HG-U133A

FZD4 PTBP3 SLC19A1

2.16e-041971436975_DN
Drughaloperidol; Up 200; 10uM; HL60; HT_HG-U133A

FZD4 DMXL2 CPN2

2.16e-041971436203_UP
DrugNiacin [59-67-6]; Down 200; 32.4uM; HL60; HT_HG-U133A

PTBP3 DMXL2 TMEM161A

2.16e-041971433043_DN
DrugAcetylsalicylsalicylic acid [530-75-6]; Up 200; 13.4uM; HL60; HG-U133A

PTBP3 SLC19A1 TMEM161A

2.20e-041981431377_UP
DrugLoperamide hydrochloride [34552-83-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A

PTBP3 SLC19A1 TMEM161A

2.20e-041981431533_DN
DrugAcenocoumarol [152-72-7]; Up 200; 11.4uM; MCF7; HT_HG-U133A

PTBP3 SLC19A1 ABCC4

2.20e-041981437232_UP
DrugKhellin [82-02-0]; Up 200; 15.4uM; HL60; HG-U133A

PTBP3 SLC19A1 DMXL2

2.23e-041991432004_UP
DrugNorethynodrel [68-23-5]; Down 200; 13.4uM; MCF7; HT_HG-U133A

PTBP3 SLC19A1 ABCC4

2.23e-041991437471_DN
Druggamma-Glu-Gly

GPI GRINA

2.31e-0437142CID000100099
Drug4-methylumbelliferyl glucuronide

GPI ABCC4

2.44e-0438142CID000091553
Drug4-amino-2,6-dinitrotoluene

GPI SLC19A1 TMEM69 ABCC4

2.61e-04541144ctd:C035207
DrugAC1NV8O5

SLC19A1 ABCC4

3.42e-0445142CID005473386
DrugMPEP

GPI GRINA

5.89e-0459142CID003025961
DiseaseCleft palate, isolated

FZD4 SLC19A1

2.05e-0442152C1837218
DiseaseCleft Palate

FZD4 SLC19A1

7.64e-0481152C0008925
DiseaseDrug toxicity

SLC19A1 ABCC4

8.21e-0484152C0013221
DiseaseAdverse reaction to drug

SLC19A1 ABCC4

8.21e-0484152C0041755
DiseaseColorectal Carcinoma

FZD4 SLC19A1 ABCC4

4.93e-03702153C0009402
DiseaseColorectal Neoplasms

SLC19A1 ABCC4

8.51e-03277152C0009404

Protein segments in the cluster

PeptideGeneStartEntry
TKNIIFVETSFTTLE

CPN2

51

P22792
VTFADKSAFTTVLTV

DMXL2

626

Q8TDJ6
TLSTVSVFTFVAEVK

GRINA

176

Q7Z429
FIIASKTFTTQETIT

GPI

206

P06744
VSYTLIIVSIFKISS

OR13C2

216

Q8NGS9
LASFFSASKIIVFVT

ABCC4

321

O15439
SASKIIVFVTFTTYV

ABCC4

326

O15439
FISTAFTVLTFLIDS

FZD4

231

Q9ULV1
LLTVTFSIKMFLTVT

TMEM161A

141

Q9NX61
ETFLFAVILSTFTTV

PIGF

111

Q07326
LATFSFIITLVVKSS

TMEM69

221

Q5SWH9
IITTTRKFFTILASV

SLC35B1

271

P78383
TFSTISEKVIFFELI

TMED5

111

Q9Y3A6
GVNTFFATIVKTIIT

SLC19A1

401

P41440
FATIVKTIITFIVSD

SLC19A1

406

P41440
IFSKFGTVLKIITFT

PTBP3

201

O95758
FFTTVVVTSSIILFK

NIPAL4

301

Q0D2K0