Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	choline-phosphate cytidylyltransferase activity	PCYT1A PCYT1B	4.11e-06	2	41	2	GO:0004105
GeneOntologyMolecularFunction	structural constituent of eye lens	CRYGA CRYGB CRYGD	1.58e-05	24	41	3	GO:0005212
GeneOntologyMolecularFunction	phosphatidylcholine binding	PCYT1A RASGRP1 PCYT1B	4.60e-05	34	41	3	GO:0031210
GeneOntologyMolecularFunction	quaternary ammonium group binding	PCYT1A RASGRP1 PCYT1B	1.15e-04	46	41	3	GO:0050997
GeneOntologyMolecularFunction	cytidylyltransferase activity	PCYT1A PCYT1B	1.83e-04	10	41	2	GO:0070567
GeneOntologyMolecularFunction	lamin binding	PKP1 PRNP	6.88e-04	19	41	2	GO:0005521
GeneOntologyMolecularFunction	lipid binding	BPIFB4 PCYT1A RASGRP1 PLA2G2E PPP5C SNAP91 PCYT1B PSMB4	7.77e-04	988	41	8	GO:0008289
GeneOntologyMolecularFunction	structural molecule activity	PKP1 CRYGA CRYGB CRYGD FBN1 CLDN2 ADD3	2.05e-03	891	41	7	GO:0005198
GeneOntologyCellularComponent	proteasome core complex, beta-subunit complex	PSMB4 PSMB5	2.04e-04	11	41	2	GO:0019774
GeneOntologyCellularComponent	proteasome core complex	PSMB4 PSMB5	6.97e-04	20	41	2	GO:0005839
GeneOntologyCellularComponent	axon terminus	SRSF10 PNMT SNAP91 PRNP	7.49e-04	210	41	4	GO:0043679
GeneOntologyCellularComponent	neuronal cell body	CACNA1D SRSF10 INPP5F PPP5C PNMT SNAP91 PPP1R9A	1.09e-03	835	41	7	GO:0043025
GeneOntologyCellularComponent	neuron projection terminus	SRSF10 PNMT SNAP91 PRNP	1.10e-03	233	41	4	GO:0044306
GeneOntologyCellularComponent	dendrite	CACNA1D SRSF10 INPP5F PPP5C PNMT PRNP PPP1R9A	1.27e-03	858	41	7	GO:0030425
GeneOntologyCellularComponent	dendritic tree	CACNA1D SRSF10 INPP5F PPP5C PNMT PRNP PPP1R9A	1.29e-03	860	41	7	GO:0097447
GeneOntologyCellularComponent	distal axon	SRSF10 PNMT SNAP91 PRNP PPP1R9A	1.54e-03	435	41	5	GO:0150034
GeneOntologyCellularComponent	cell body	CACNA1D SRSF10 INPP5F PPP5C PNMT SNAP91 PPP1R9A	2.00e-03	929	41	7	GO:0044297
MousePheno	nuclear cataract	CRYGA CRYGB CRYGD	3.29e-05	26	34	3	MP:0010254
Domain	Crystall	CRYGA CRYGB CRYGD	4.07e-06	15	40	3	PF00030
Domain	CRYSTALLIN_BETA_GAMMA	CRYGA CRYGB CRYGD	4.07e-06	15	40	3	PS50915
Domain	Beta/gamma_crystallin	CRYGA CRYGB CRYGD	4.07e-06	15	40	3	IPR001064
Domain	XTALbg	CRYGA CRYGB CRYGD	4.07e-06	15	40	3	SM00247
Domain	G_crystallin-rel	CRYGA CRYGB CRYGD	7.26e-06	18	40	3	IPR011024
Domain	Cyt_trans-like	PCYT1A PCYT1B	9.33e-05	7	40	2	IPR004821
Domain	CTP_transf_like	PCYT1A PCYT1B	9.33e-05	7	40	2	PF01467
Domain	PROTEASOME_BETA_2	PSMB4 PSMB5	2.43e-04	11	40	2	PS51476
Domain	Proteasome_suB-type	PSMB4 PSMB5	2.43e-04	11	40	2	IPR023333
Domain	PROTEASOME_BETA_1	PSMB4 PSMB5	2.43e-04	11	40	2	PS00854
Domain	Proteasome_bsu_CS	PSMB4 PSMB5	2.91e-04	12	40	2	IPR016050
Domain	Proteasome	PSMB4 PSMB5	7.47e-04	19	40	2	PF00227
Domain	Proteasome_sua/b	PSMB4 PSMB5	7.47e-04	19	40	2	IPR001353
Domain	-	PSMB4 PSMB5	1.20e-03	24	40	2	3.60.20.10
Domain	Calcineurin-like_PHP_ApaH	TMEM62 PPP5C	1.63e-03	28	40	2	IPR004843
Domain	Metallophos	TMEM62 PPP5C	1.63e-03	28	40	2	PF00149
Domain	Metallo-depent_PP-like	TMEM62 PPP5C	1.87e-03	30	40	2	IPR029052
Domain	-	TMEM62 PPP5C	1.87e-03	30	40	2	3.60.21.10
Domain	Ntn_hydrolases_N	PSMB4 PSMB5	2.26e-03	33	40	2	IPR029055
Domain	Rossmann-like_a/b/a_fold	PCYT1A PCYT1B	3.82e-03	43	40	2	IPR014729
Domain	-	PCYT1A PCYT1B	3.82e-03	43	40	2	3.40.50.620
Domain	TPR-contain_dom	SMG7 PPP5C TTC4	4.04e-03	150	40	3	IPR013026
Domain	TPR	SMG7 PPP5C TTC4	5.26e-03	165	40	3	PS50005
Domain	TPR_REGION	SMG7 PPP5C TTC4	5.26e-03	165	40	3	PS50293
Pathway	KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_26S_PROTEASOME_MEDIATED_PROTEIN_DEGRADATION	PRNP PSMB4 PSMB5	6.55e-05	36	31	3	M47758
Pathway	KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_VGCC_CA2_APOPTOTIC_PATHWAY	CACNA1D PRNP	6.98e-05	6	31	2	M47762
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX2	RBM14 PSMB4 PSMB5	3.34e-04	62	31	3	MM15521
Pathway	WP_KENNEDY_PATHWAY_FROM_SPHINGOLIPIDS	PCYT1A PCYT1B	4.19e-04	14	31	2	M39620
Pathway	WP_KENNEDY_PATHWAY	PCYT1A PCYT1B	4.19e-04	14	31	2	MM15980
Pathway	KEGG_GLYCEROPHOSPHOLIPID_METABOLISM	PCYT1A PLA2G2E PCYT1B	6.31e-04	77	31	3	M9131
Pathway	REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR	RASGRP1 PSMB4 PSMB5	6.31e-04	77	31	3	MM14513
Pathway	REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR	RASGRP1 PSMB4 PSMB5	7.32e-04	81	31	3	M595
Pathway	BIOCARTA_PROTEASOME_PATHWAY	PSMB4 PSMB5	7.82e-04	19	31	2	M194
Pathway	REACTOME_PHOSPHOLIPID_METABOLISM	PCYT1A INPP5F PLA2G2E PCYT1B	8.50e-04	196	31	4	MM14591
Pubmed	Three murine cataract mutants (Cat2) are defective in different gamma-crystallin genes.	CRYGA CRYGB CRYGD	1.52e-09	3	41	3	9782080
Pubmed	Gamma-crystallin family of the mouse lens: structural and evolutionary relationships.	CRYGA CRYGB CRYGD	1.52e-09	3	41	3	6096855
Pubmed	Multiple gamma-crystallins of the mouse lens: fractionation of mRNAs by cDNA cloning.	CRYGA CRYGB CRYGD	1.52e-09	3	41	3	6953430
Pubmed	Homology models of human gamma-crystallins: structural study of the extensive charge network in gamma-crystallins.	CRYGA CRYGB CRYGD	6.08e-09	4	41	3	12507494
Pubmed	Reduced levels of gamma-crystallin transcripts during embryonic development of murine Cat2nop mutant lenses.	CRYGA CRYGB CRYGD	6.08e-09	4	41	3	8626090
Pubmed	Differential regulation of gamma-crystallin genes during mouse lens development.	CRYGA CRYGB CRYGD	6.08e-09	4	41	3	3792630
Pubmed	The mouse eye lens obsolescence (Elo) mutant: studies on crystallin gene expression and linkage analysis between the mutant locus and the gamma-crystallin genes.	CRYGA CRYGB CRYGD	6.08e-09	4	41	3	3428594
Pubmed	Novel mutations in the gamma-crystallin genes cause autosomal dominant congenital cataracts.	CRYGA CRYGB CRYGD	6.08e-09	4	41	3	12011157
Pubmed	Genetic and allelic heterogeneity of Cryg mutations in eight distinct forms of dominant cataract in the mouse.	CRYGA CRYGB CRYGD	6.08e-09	4	41	3	15037589
Pubmed	Assignment of the human gamma-crystallin gene cluster (CRYG) to the long arm of chromosome 2, region q33-36.	CRYGA CRYGB CRYGD	6.08e-09	4	41	3	3011643
Pubmed	Temporal regulation of six crystallin transcripts during mouse lens development.	CRYGA CRYGB CRYGD	6.08e-09	4	41	3	1623964
Pubmed	Structure of the crystallins.	CRYGA CRYGB CRYGD	1.52e-08	5	41	3	10627816
Pubmed	The crystallins: genes, proteins and diseases.	CRYGA CRYGB CRYGD	1.52e-08	5	41	3	9426193
Pubmed	Human gamma-crystallin genes. A gene family on its way to extinction.	CRYGA CRYGB CRYGD	3.03e-08	6	41	3	2258929
Pubmed	Gamma-crystallins of the human eye lens: expression analysis of five members of the gene family.	CRYGA CRYGB CRYGD	3.03e-08	6	41	3	3670288
Pubmed	Sox1 directly regulates the gamma-crystallin genes and is essential for lens development in mice.	CRYGA CRYGB CRYGD	1.81e-07	10	41	3	9512512
Pubmed	Regulation of lens fiber cell differentiation by transcription factor c-Maf.	CRYGA CRYGB CRYGD	1.81e-07	10	41	3	10383433
Pubmed	Disruption of Trkb-mediated signaling induces disassembly of postsynaptic receptor clusters at neuromuscular junctions.	CRYGA CRYGB CRYGD	2.49e-07	11	41	3	10595510
Pubmed	Multiple developmental defects derived from impaired recruitment of ASC-2 to nuclear receptors in mice: implication for posterior lenticonus with cataract.	CRYGA CRYGB CRYGD	2.49e-07	11	41	3	12446761
Pubmed	E2F1 mediates ectopic proliferation and stage-specific p53-dependent apoptosis but not aberrant differentiation in the ocular lens of Rb deficient fetuses.	CRYGA CRYGB CRYGD	2.49e-07	11	41	3	11146559
Pubmed	Altered aggregation properties of mutant gamma-crystallins cause inherited cataract.	CRYGA CRYGB CRYGD	3.32e-07	12	41	3	12426373
Pubmed	The orchestration of mammalian tissue morphogenesis through a series of coherent feed-forward loops.	CRYGA CRYGB CRYGD	5.49e-07	14	41	3	21998302
Pubmed	Prox1 function is crucial for mouse lens-fibre elongation.	CRYGA CRYGB CRYGD	6.85e-07	15	41	3	10080188
Pubmed	Unique contribution of heat shock transcription factor 4 in ocular lens development and fiber cell differentiation.	CRYGA CRYGB CRYGD	8.42e-07	16	41	3	15593327
Pubmed	HSF4 is required for normal cell growth and differentiation during mouse lens development.	CRYGA CRYGB CRYGD	1.02e-06	17	41	3	15483628
Pubmed	The gene map of the Norway rat (Rattus norvegicus) and comparative mapping with mouse and man.	CRYGA CRYGB CRYGD F5	1.14e-06	66	41	4	1889815
Pubmed	Regulation of ocular lens development by Smad-interacting protein 1 involving Foxe3 activation.	CRYGA CRYGB CRYGD	1.23e-06	18	41	3	16162653
Pubmed	Distribution of CTP:phosphocholine cytidylyltransferase (CCT) isoforms. Identification of a new CCTbeta splice variant.	PCYT1A PCYT1B	1.36e-06	2	41	2	10480912
Pubmed	Analysis of single nucleotide polymorphisms of CRYGA and CRYGB genes in control population of western Indian origin.	CRYGA CRYGB	1.36e-06	2	41	2	19384013
Pubmed	Differential dephosphorylation of CTP:phosphocholine cytidylyltransferase upon translocation to nuclear membranes and lipid droplets.	PCYT1A PCYT1B	1.36e-06	2	41	2	32186954
Pubmed	Gamma-D crystallin gene (CRYGD) mutation causes autosomal dominant congenital cerulean cataracts.	CRYGB CRYGD	1.36e-06	2	41	2	12676897
Pubmed	CTP:phosphocholine cytidylyltransferase: Function, regulation, and structure of an amphitropic enzyme required for membrane biogenesis.	PCYT1A PCYT1B	1.36e-06	2	41	2	26165797
Pubmed	Gene structure, expression and identification of a new CTP:phosphocholine cytidylyltransferase beta isoform.	PCYT1A PCYT1B	1.36e-06	2	41	2	12842190
Pubmed	Linkage analysis of the mutation locus in the eye lens obsolescence (Elo) mouse.	CRYGA CRYGD	4.06e-06	3	41	2	2571575
Pubmed	Activation of the gamma E-crystallin pseudogene in the human hereditary Coppock-like cataract.	CRYGA CRYGD	4.06e-06	3	41	2	8004095
Pubmed	Methylation and carbamylation of human gamma-crystallins.	CRYGB CRYGD	4.06e-06	3	41	2	12876325
Pubmed	Assigning functions to distinct regions of the N-terminus of the prion protein that are involved in its copper-stimulated, clathrin-dependent endocytosis.	SNAP91 PRNP	4.06e-06	3	41	2	16254249
Pubmed	The gamma-crystallins and human cataracts: a puzzle made clearer.	CRYGB CRYGD	4.06e-06	3	41	2	10521291
Pubmed	The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation.	RBM14 PCYT1A SRSF10 F5 ADD3 PSMB4 PSMB5	6.20e-06	604	41	7	37616343
Pubmed	Early embryonic lethality in mice with targeted deletion of the CTP:phosphocholine cytidylyltransferase alpha gene (Pcyt1a).	PCYT1A PCYT1B	8.12e-06	4	41	2	15798219
Pubmed	Allelism tests of 15 dominant cataract mutations in mice.	CRYGB CRYGD	8.12e-06	4	41	2	1511869
Pubmed	Relationships among the subunits of the high molecular weight proteinase, macropain (proteasome).	PSMB4 PSMB5	8.12e-06	4	41	2	2306472
Pubmed	Partially folded aggregation intermediates of human gammaD-, gammaC-, and gammaS-crystallin are recognized and bound by human alphaB-crystallin chaperone.	CRYGB CRYGD	8.12e-06	4	41	2	20621668
Pubmed	Disruption of Rest Leads to the Early Onset of Cataracts with the Aberrant Terminal Differentiation of Lens Fiber Cells.	CRYGA CRYGB CRYGD	1.15e-05	37	41	3	27631609
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	RBM14 PKP1 SCAF11 SRSF10 RFC1 TOPORS F5 ADD3 PSMB5	1.26e-05	1257	41	9	36526897
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	RBM14 PKP1 SCAF11 SRSF10 RFC1 FECH	6.98e-05	601	41	6	33658012
Pubmed	Shotgun identification of protein modifications from protein complexes and lens tissue.	CRYGB CRYGD	7.41e-05	11	41	2	12060738
Pubmed	Mapping of six dominant cataract genes in the mouse.	CRYGA CRYGD	7.41e-05	11	41	2	8034315
Pubmed	The complete primary structure of mouse 20S proteasomes.	PSMB4 PSMB5	7.41e-05	11	41	2	10436176
Pubmed	Report and abstracts of the Fourth International Workshop on Human Chromosome 2 Mapping 1996.	CRYGA CRYGB CRYGD	8.22e-05	71	41	3	8751373
Pubmed	Cooperation of multiple chaperones required for the assembly of mammalian 20S proteasomes.	PSMB4 PSMB5	1.22e-04	14	41	2	17189198
Pubmed	Intermediates in the formation of mouse 20S proteasomes: implications for the assembly of precursor beta subunits.	PSMB4 PSMB5	1.22e-04	14	41	2	9311996
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	RBM14 DNAJB12 SRSF10 RFC1 FECH PSMB4 PSMB5	1.27e-04	971	41	7	33306668
Pubmed	Polo-like kinase interacts with proteasomes and regulates their activity.	PSMB4 PSMB5	1.41e-04	15	41	2	11205743
Pubmed	The ubiquitin-like modifier FAT10 is degraded by the 20S proteasome in vitro but not in cellulo.	PSMB4 PSMB5	1.41e-04	15	41	2	37012049
Pubmed	HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis.	CUL7 RFC1 FECH	1.50e-04	87	41	3	33711283
Pubmed	A novel PrP partner HS-1 associated protein X-1 (HAX-1) protected the cultured cells against the challenge of H₂O₂.	PRNP PSMB5	1.61e-04	16	41	2	21301993
Pubmed	Human proteasome subunits from 2-dimensional gels identified by partial sequencing.	PSMB4 PSMB5	1.61e-04	16	41	2	7811265
Pubmed	Differentially expressed genes in the lens of mimecan-null mice.	CRYGA CRYGD	1.82e-04	17	41	2	15215744
Pubmed	A quantitative proteomic approach using two-dimensional gel electrophoresis and isotope-coded affinity tag labeling for studying human 20S proteasome heterogeneity.	PSMB4 PSMB5	1.82e-04	17	41	2	15887188
Pubmed	The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4WDTC1 E3 ligase.	RBM14 DNAJB12 PKP1 CUL7 PSMB5	1.87e-04	453	41	5	27113764
Pubmed	Transcription factor GATA-3 is essential for lens development.	CRYGA CRYGD	2.05e-04	18	41	2	19623612
Pubmed	Loss of FBXO7 (PARK15) results in reduced proteasome activity and models a parkinsonism-like phenotype in mice.	PSMB4 PSMB5	2.29e-04	19	41	2	27497298
Pubmed	Transcriptomic analysis and novel insights into lens fibre cell differentiation regulated by Gata3.	CRYGA CRYGB	2.29e-04	19	41	2	31847788
Pubmed	SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.	RBM14 SCAF11 SRSF10 RFC1	2.41e-04	258	41	4	37794589
Pubmed	The proteasome maturation protein POMP facilitates major steps of 20S proteasome formation at the endoplasmic reticulum.	PSMB4 PSMB5	2.81e-04	21	41	2	17948026
Pubmed	The X-Linked-Intellectual-Disability-Associated Ubiquitin Ligase Mid2 Interacts with Astrin and Regulates Astrin Levels to Promote Cell Division.	PSMB4 PSMB5	3.09e-04	22	41	2	26748699
Pubmed	Mass spectrometry-based proteomic analysis of FSCN1-interacting proteins in laryngeal squamous cell carcinoma cells.	RFC1 PSMB4 PSMB5	3.88e-04	120	41	3	31298480
Pubmed	Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.	CACNA1D ANTXR1 SNAP91	4.69e-04	128	41	3	30995482
Pubmed	Label-free quantitative proteomics and SAINT analysis enable interactome mapping for the human Ser/Thr protein phosphatase 5.	PPP5C TTC4	5.39e-04	29	41	2	21360678
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	DNAJB12 SRSF10 RFC1 PPP5C TOPORS PSMB4 PSMB5	5.79e-04	1247	41	7	27684187
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	RBM14 DNAJB12 RFC1 TTC4 FECH PSMB4 PSMB5	6.07e-04	1257	41	7	37317656
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	RBM14 CUL7 SMG7 TOPORS TTC4	6.16e-04	588	41	5	38580884
Pubmed	Liver and brain differential expression of one-carbon metabolism genes during ontogenesis.	PCYT1A PCYT1B	7.00e-04	33	41	2	34702858
Pubmed	Recognition and processing of ubiquitin-protein conjugates by the proteasome.	PSMB4 PSMB5	7.00e-04	33	41	2	19489727
Pubmed	Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease.	NSD1 F5	7.00e-04	33	41	2	22703881
Pubmed	Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome.	PSMB4 PSMB5	7.00e-04	33	41	2	29636472
Pubmed	The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function.	CACNA1D ADD3	7.00e-04	33	41	2	22357600
Pubmed	An atomic structure of the human 26S proteasome.	PSMB4 PSMB5	7.43e-04	34	41	2	27428775
Pubmed	Redifferentiation of dedifferentiated chondrocytes and chondrogenesis of human bone marrow stromal cells via chondrosphere formation with expression profiling by large-scale cDNA analysis.	TOPORS F5	7.43e-04	34	41	2	12878157
Pubmed	TTF-1/NKX2-1 binds to DDB1 and confers replication stress resistance to lung adenocarcinomas.	RBM14 SRSF10 RFC1	7.72e-04	152	41	3	28192407
Pubmed	Angelman syndrome-associated point mutations in the Zn2+-binding N-terminal (AZUL) domain of UBE3A ubiquitin ligase inhibit binding to the proteasome.	PSMB4 PSMB5	7.87e-04	35	41	2	30257870
Pubmed	Mapping the murine cardiac 26S proteasome complexes.	PSMB4 PSMB5	7.87e-04	35	41	2	16857966
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	RBM14 NSD1 SCAF11 SRSF10 RFC1 SNAP91	8.30e-04	954	41	6	36373674
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	RBM14 SRSF10 RFC1 PPP5C TTC4 PSMB4 PSMB5	8.65e-04	1335	41	7	29229926
Pubmed	Structure and functions of the 20S and 26S proteasomes.	PSMB4 PSMB5	8.80e-04	37	41	2	8811196
Pubmed	Hypermutation of HIV-1 DNA in the absence of the Vif protein.	PSMB4 PSMB5	8.80e-04	37	41	2	12750511
Pubmed	Good to CU.	PSMB4 PSMB5	8.80e-04	37	41	2	12840737
Pubmed	Comprehensive investigation of the molecular defect in vif-deficient human immunodeficiency virus type 1 virions.	PSMB4 PSMB5	8.80e-04	37	41	2	12719574
Pubmed	An endogenous inhibitor of human immunodeficiency virus in human lymphocytes is overcome by the viral Vif protein.	PSMB4 PSMB5	8.80e-04	37	41	2	9811770
Pubmed	Death by deamination: a novel host restriction system for HIV-1.	PSMB4 PSMB5	8.80e-04	37	41	2	12914693
Pubmed	RITA1 drives the growth of bladder cancer cells by recruiting TRIM25 to facilitate the proteasomal degradation of RBPJ.	PSMB4 PSMB5	8.80e-04	37	41	2	35701858
Pubmed	Evidence for a newly discovered cellular anti-HIV-1 phenotype.	PSMB4 PSMB5	8.80e-04	37	41	2	9846577
Pubmed	DNA deamination: not just a trigger for antibody diversification but also a mechanism for defense against retroviruses.	PSMB4 PSMB5	8.80e-04	37	41	2	12830140
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	RBM14 PKP1 CUL7 FECH PSMB5	8.94e-04	639	41	5	23443559
Pubmed	The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA.	PSMB4 PSMB5	9.28e-04	38	41	2	12808465
Pubmed	Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts.	PSMB4 PSMB5	9.28e-04	38	41	2	12808466
Pubmed	HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability.	PSMB4 PSMB5	9.28e-04	38	41	2	14527406
Pubmed	Degradation of HIV-1 integrase by the N-end rule pathway.	PSMB4 PSMB5	9.28e-04	38	41	2	10893419
Pubmed	DNA deamination mediates innate immunity to retroviral infection.	PSMB4 PSMB5	9.28e-04	38	41	2	12809610
Cytoband	2q34	CRYGA CRYGB	2.90e-04	28	41	2	2q34
Cytoband	Ensembl 112 genes in cytogenetic band chr2q33	CRYGA CRYGB CRYGD	8.25e-04	205	41	3	chr2q33
GeneFamily	Beta-gamma crystallins	CRYGA CRYGB CRYGD	1.19e-06	15	26	3	1359
GeneFamily	Proteasome	PSMB4 PSMB5	1.73e-03	43	26	2	690
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	SRSF10 PPP1R9A PCIF1	2.17e-03	181	26	3	694
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-hematologic-hematopoietic_progenitor\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CRYGD FBN1 PNMT PCYT1B	2.24e-05	180	41	4	f598bb9df0d784120847fada2d9a2a88b8b68cd1
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CRYGD FBN1 PNMT PCYT1B	2.24e-05	180	41	4	b4fa047f271c7b56940bdc85c912f50aa5b5ca82
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ANTXR1 FBN1 PLA2G2E ADD3	2.49e-05	185	41	4	d5f5866924648a3c14e2596218fd548a31777aa3
ToppCell	systemic_lupus_erythematosus-managed-Hematopoietic-progenitor_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CRYGD FBN1 PNMT PCYT1B	2.71e-05	189	41	4	6687a93ac8540ece5fd762f6f77c1f25f159195b
ToppCell	10x5'v1-week_12-13-Mesenchymal_fibro-stroma-endosteal_fibroblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PKP1 TMEM30B FBN1 SNAP91	2.71e-05	189	41	4	473b01c9162b12b90a617c600238436177a0d18d
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Myofibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PNMT CLDN2 PRNP PPP1R9A	2.82e-05	191	41	4	9d3fa8d8138700640cc7927521c7635299df697d
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1D TMEM30B CRYGD CLDN2	2.82e-05	191	41	4	a8d77095ba20b47fc70ba04f80759fbce873253d
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-pulmonary_interstitial_fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PNMT CLDN2 PRNP PPP1R9A	2.82e-05	191	41	4	d04ed1e04b8cb904237d8e8388fe7740c724237b
ToppCell	Control-Treg\|Control / Disease group and Cell class	INPP5F F5 PRNP ADD3	2.88e-05	192	41	4	3a9a8ac2aa278adde848608f9bb92a002dbb9bcc
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F_2\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RASGRP1 SCAF11 TOPORS ADD3	3.12e-05	196	41	4	ea8eceacc5d5e1a22b77c31e7c45985dc7bb15de
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANTXR1 TMEM30B FBN1 ADD3	3.12e-05	196	41	4	2029f58ce6a7b8c35d3a7496c3341391990909ce
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma\|TCGA-Liver / Sample_Type by Project: Shred V9	DXO CUL7 PSMB4 PSMB5	3.37e-05	200	41	4	9cff8be6e566f342fc8b45e93106d033b14759ee
ToppCell	TCGA-Liver-Primary_Tumor\|TCGA-Liver / Sample_Type by Project: Shred V9	DXO CUL7 PSMB4 PSMB5	3.37e-05	200	41	4	b667168081393433597f6ca8baeddba1d1906d40
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2-Endothelial_Tip.Dcn.1500015O10Rik_(1500015O10Rik)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TMEM30B PLA2G2E CLDN2	1.57e-04	114	41	3	c3feca81edee445cbe5e46a07e1a59327dc2e981
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2-Endothelial_Tip.Dcn.1500015O10Rik_(1500015O10Rik)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TMEM30B PLA2G2E CLDN2	1.57e-04	114	41	3	89350483d2ce57afc612fe25398e35af121d50f0
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-innate_lymphocytic-immature_natural_killer_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PNMT SNAP91 PPP1R9A	3.26e-04	146	41	3	40fac8a298152ec7f7eeeed5a2d28541aea3b338
ToppCell	367C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	BPIFB4 SAA4 PNMT	3.88e-04	155	41	3	8dab23aad905cc35a35643baa0554acb3f6fe6c8
ToppCell	367C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	BPIFB4 SAA4 PNMT	3.88e-04	155	41	3	42533beaded07068f00540de704de07e4f19abcf
ToppCell	10x5'-Lung-Lymphocytic_T_CD4-Tregs\|Lung / Manually curated celltypes from each tissue	PKP1 RASGRP1 F5	4.11e-04	158	41	3	f433bc189f000efa34e8e09ab32b3fa22bcf64c4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PNMT F5 PCYT1B	4.50e-04	163	41	3	2d6fd2562d78be9f83fa35d811eb7e27eb8cc5d1
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Keratinizing_Cervical_Squamous_Cell_Carcinoma\|TCGA-Cervix / Sample_Type by Project: Shred V9	PKP1 SLC20A2 PRNP	4.58e-04	164	41	3	de1646dbcf2a10b48e021acf7dc63e803e6a47ce
ToppCell	tumor_Lung-T/NK_cells-Cytotoxic_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	CRYGD SAA4 CLDN2	4.58e-04	164	41	3	60fe6bb86afaebd92590135f08f5434ce0d8d73c
ToppCell	severe-HSPC\|severe / disease stage, cell group and cell class	FBN1 PNMT PCYT1B	4.66e-04	165	41	3	acd837d88ad3786c263f74651a6c0e02fa2fa2c5
ToppCell	LAM-Myeloid-Mast\|LAM / Condition, Lineage and Cell class	CRYGD PNMT SNAP91	4.74e-04	166	41	3	e0ce973cc2a091b832c67b3b32dc153379daa2ef
ToppCell	10x5'-bone_marrow-Hematopoietic_progenitors-Progenitor_MEMP\|bone_marrow / Manually curated celltypes from each tissue	CRYGD FBN1 PNMT	4.74e-04	166	41	3	9788486582cc2c5f28b9ea015e235732f9fefb1e
ToppCell	367C-Fibroblasts-Fibroblast-G-\|367C / Donor, Lineage, Cell class and subclass (all cells)	CACNA1D ANTXR1 FBN1	4.91e-04	168	41	3	b8c65542a0701ae31f49d332d87a64578e24b4e3
ToppCell	367C-Fibroblasts-Fibroblast-G\|367C / Donor, Lineage, Cell class and subclass (all cells)	CACNA1D ANTXR1 FBN1	4.91e-04	168	41	3	8c95093b1ea45826f62893edd3c410fe53b563a4
ToppCell	severe-HSPC\|World / disease stage, cell group and cell class	FBN1 PNMT PCYT1B	5.00e-04	169	41	3	b0421b73bfdc92f7a2762b4b670b9eae124aa702
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Microfold_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	F5 CLDN2 PPP1R9A	5.00e-04	169	41	3	a54a8494c1feff29d77ab4737fcfabc84ace5c94
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PNMT SNAP91 PPP1R9A	5.08e-04	170	41	3	6c65ddb496030bb479ef346cc37a9d4dfa6b824f
ToppCell	COVID-19_Convalescent-Hematopoietic_SC\|COVID-19_Convalescent / Disease group, lineage and cell class	FBN1 PNMT PCYT1B	5.08e-04	170	41	3	8a73d5334eed1cd9fdcc3ebeae0bdf9f945c228a
ToppCell	P28-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TMEM30B PRNP PPP1R9A	5.08e-04	170	41	3	d0ed3a8a7ad96c05641ec409b0a69c4fb094893c
ToppCell	PBMC-Convalescent-Hematopoietic-HSPC\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FBN1 PNMT PCYT1B	5.17e-04	171	41	3	172db31a37b72fb87fe5f0f79da51866b90dd1ad
ToppCell	PBMC-Convalescent-Hematopoietic-HSPC-HSPC\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FBN1 PNMT PCYT1B	5.17e-04	171	41	3	2031797d579ce373921affad70da6e50eec13664
ToppCell	remission-HSPC\|remission / disease stage, cell group and cell class	FBN1 PNMT PCYT1B	5.17e-04	171	41	3	41b424e58470a2fc25632aea50a37c7c5ea17645
ToppCell	PBMC-Convalescent-Hematopoietic-HSPC-HSPC-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FBN1 PNMT PCYT1B	5.17e-04	171	41	3	a4e13b304ef414722ffdc06560deeab41785e956
ToppCell	PBMC-Convalescent-Hematopoietic-HSPC-HSPC-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FBN1 PNMT PCYT1B	5.26e-04	172	41	3	8fd3db757d54949bd583d5f0eadf63a32342cb9d
ToppCell	PBMC-Convalescent-Hematopoietic-HSPC-HSPC\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	FBN1 PNMT PCYT1B	5.26e-04	172	41	3	382cb5fea099110eb026a8bba6cf4c28763ea52f
ToppCell	PBMC-Convalescent-Hematopoietic-HSPC\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	FBN1 PNMT PCYT1B	5.26e-04	172	41	3	da78f7a71b7f05c5c484c9ed19ba37c55d35e870
ToppCell	Control-Lymphoid-Tregs\|Lymphoid / Condition, Lineage and Cell class	INPP5F F5 PRNP	5.44e-04	174	41	3	522a6d5d9809271c63b85f62ac6ec52a6e3c355e
ToppCell	severe_COVID-19-HSPC\|severe_COVID-19 / disease group, cell group and cell class (v2)	CRYGD FBN1 PNMT	5.44e-04	174	41	3	6d35bacf073537b272ff821e604c899fb9ce6a7c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANTXR1 SAA4 FBN1	5.53e-04	175	41	3	795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell	3'_v3-blood-Mast-Mast_cell_granulo-myelo\|blood / Manually curated celltypes from each tissue	CACNA1D PNMT PCYT1B	5.62e-04	176	41	3	d421b6b8e13894dbcf29548c0a6516c3dee8f9b1
ToppCell	T_cells-Tph_and_Tfh\|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	INPP5F F5 FECH	5.62e-04	176	41	3	56c055488e34605d32562571a2fee621b47c9441
ToppCell	5'-Adult-LymphNode-Hematopoietic-Myeloid-Mast_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PNMT TTC4 FECH	5.62e-04	176	41	3	0d203682c372411ba64e97a8eae6c4788e8b6ecf
ToppCell	3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-ILC2\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1D RASGRP1 PNMT	5.81e-04	178	41	3	5101a45595cd8d702f911afadf1eb0ee10bdcefc
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	ANTXR1 FBN1 SMG7	5.81e-04	178	41	3	edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCell	10x5'v1-week_17-19-Hematopoietic-erythroid-early_erythroid\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PNMT FECH PCYT1B	5.91e-04	179	41	3	3f73f89905c061ada4e3eb921fa394d95f95c959
ToppCell	COVID-19_Mild-Hematopoietic_SC-HSPC\|COVID-19_Mild / Disease group, lineage and cell class	CRYGD FBN1 PNMT	5.91e-04	179	41	3	19fcf48f5e02e4cb2b328efb4502f337e1282f72
ToppCell	COVID-19_Mild-Hematopoietic_SC\|COVID-19_Mild / Disease group, lineage and cell class	CRYGD FBN1 PNMT	5.91e-04	179	41	3	50a073166e34bcfa52a62c4dafb3aef724e0fa8e
ToppCell	TCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	PRNP PSMB4 PSMB5	6.10e-04	181	41	3	1168164994d5e2072c80d058e42aab72a0cf9867
ToppCell	systemic_lupus_erythematosus-managed-Hematopoietic-progenitor_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CRYGD PNMT PCYT1B	6.10e-04	181	41	3	070ae3f3fe0e177fabcf34e64a0f158b01354837
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM30B F5 SLC20A2	6.20e-04	182	41	3	770ce9f3f4538d0181a0181543841bc964c68274
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM30B F5 SLC20A2	6.20e-04	182	41	3	77ab860e2add49dad0c1ffbfc64278ad499dfbd5
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM30B F5 SLC20A2	6.20e-04	182	41	3	4921c7d5687cc79f896b39753bb621d7e3d2972f
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-hematologic\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CRYGD FECH PCYT1B	6.30e-04	183	41	3	1db466cf757813322db1cdcc0bf1d91c062fd9de
ToppCell	facs-Liver-Hepatocytes-24m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM30B F5 SLC20A2	6.30e-04	183	41	3	d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCell	10x5'v1-week_17-19-Hematopoietic-erythroid\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PNMT FECH PCYT1B	6.40e-04	184	41	3	0efc757d9512d6a8fe8176e977a94e4494ed9778
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3\|TCGA-Lung / Sample_Type by Project: Shred V9	PKP1 PCYT1A PCYT1B	6.40e-04	184	41	3	ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCell	Frontal_cortex-Neuronal-Excitatory\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	RASGRP1 PRNP PPP1R9A	6.40e-04	184	41	3	6e17c8151d6dc543de16d804db956c63c3fda414
ToppCell	COVID-19_Moderate-HSPC\|World / disease group, cell group and cell class	CRYGD FBN1 PNMT	6.40e-04	184	41	3	ccc93babe1fcdeb66b78e1d8414357877a7c45bd
ToppCell	3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_MEMP\|bone_marrow / Manually curated celltypes from each tissue	CRYGD FBN1 PCYT1B	6.40e-04	184	41	3	b81a2a95944cee8fec13d63dc0d95496e67aa937
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like\|lymph-node_spleen / Manually curated celltypes from each tissue	PNMT SNAP91 PPP1R9A	6.40e-04	184	41	3	d97471a4fe17cba6880ccf1a04cc00c741558124
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANTXR1 SAA4 FBN1	6.40e-04	184	41	3	e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3\|lymph-node_spleen / Manually curated celltypes from each tissue	PNMT SNAP91 PPP1R9A	6.40e-04	184	41	3	479e60f76c191253e23699c9dd7ef7efc08c59ad
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D231\|Adult / Lineage, Cell type, age group and donor	CACNA1D ANTXR1 FBN1	6.50e-04	185	41	3	fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell	COVID-19_Moderate-HSPC\|COVID-19_Moderate / disease group, cell group and cell class	CRYGD FBN1 PNMT	6.50e-04	185	41	3	cacc6ab5f26f6c803894567fb838ea06eaa7efe5
ToppCell	(8)_CD34_progenitor\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	CRYGD PNMT PCYT1B	6.60e-04	186	41	3	e69a986b8618effd61875fda528a2e44aab11868
ToppCell	(8)_CD34_progenitor\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	CRYGD PNMT PCYT1B	6.60e-04	186	41	3	943c604a7cd873faf510096d094100512ba2d6bc
ToppCell	droplet-Lung-21m-Epithelial-alveolar_epithelial-type_II_pneumocyte\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TMEM30B PRNP PPP1R9A	6.81e-04	188	41	3	068b761a7b6778bc6d6c776b5f09094aac87477e
ToppCell	droplet-Lung-21m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TMEM30B PRNP PPP1R9A	6.81e-04	188	41	3	c95134245dab9057eb1f9b54acb371470f9c8b86
ToppCell	(6)_ILC\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	PNMT SNAP91 PPP1R9A	6.81e-04	188	41	3	de7cb273899d0e0748c85f45c6b5e7f0642ab057
ToppCell	droplet-Lung-21m-Epithelial-alveolar_epithelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TMEM30B PRNP PPP1R9A	6.81e-04	188	41	3	3ee321a74f04eb0982c7b4977426946b0ae6e5a9
ToppCell	10x5'v1-week_17-19-Hematopoietic\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PNMT FECH PCYT1B	6.81e-04	188	41	3	c00ba0abd0c7bb2c8f9166a2ac6220aae4f4d857
ToppCell	(6)_ILC\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	PNMT SNAP91 PPP1R9A	6.81e-04	188	41	3	f4734d5b703678670ece204a0519cf015e180a6e
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANTXR1 FBN1 ADD3	6.92e-04	189	41	3	56f43e00d81cf3cdf0c39f8d7120f5beab72e258
ToppCell	10x3'2.3-week_12-13-Mesenchymal_fibro-stroma-endosteal_fibroblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PKP1 TMEM30B FBN1	6.92e-04	189	41	3	c392491aabe8a3e90974ab2ea123bbbe5200439d
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	TMEM30B TMEM62 PPP1R9A	6.92e-04	189	41	3	5d9da836ce4308b8458bb3be3871a0aca734b6cd
ToppCell	COVID_vent-Myeloid-Monocytic-SC_&_Eosinophil\|COVID_vent / Disease condition, Lineage, Cell class and subclass	CRYGD FBN1 PCYT1B	6.92e-04	189	41	3	2157a2d40613f7d5ce2e7dbd266df441e449cdaf
ToppCell	facs-Thymus-Epithelium-3m-Mesenchymal\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANTXR1 TMEM30B FBN1	6.92e-04	189	41	3	1db5dd1ef2a65251af2d5696622d1dd9c4ae2b55
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D ANTXR1 FBN1	6.92e-04	189	41	3	a153b83314cf52808f685296cff8c95af3f4983d
ToppCell	facs-Thymus-Epithelium-3m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANTXR1 TMEM30B FBN1	6.92e-04	189	41	3	bfb1c183a8a2752a2368b74150e66181c6a9da48
ToppCell	facs-Thymus-Epithelium-3m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANTXR1 TMEM30B FBN1	6.92e-04	189	41	3	14833feea8f80744a06ece73f813eaeff8c4dd61
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D ANTXR1 FBN1	6.92e-04	189	41	3	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANTXR1 FBN1 PRNP	6.92e-04	189	41	3	bc54ffd7bd1627a36747a80ce5139e4a69928400
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCAF11 PPP1R9A ADD3	7.02e-04	190	41	3	36e83995021ba16690f84e2077a9e8baec547d05
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like\|lymph-node_spleen / Manually curated celltypes from each tissue	SNAP91 PRNP PPP1R9A	7.02e-04	190	41	3	0c7eb8f4f2926af01bf44d5c9f239be7b81c67fe
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANTXR1 FBN1 ADD3	7.02e-04	190	41	3	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	10x3'2.3-week_14-16-Lymphocytic_NK-T_NK\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	RASGRP1 SNAP91 PPP1R9A	7.02e-04	190	41	3	67fa7472ec534179087963177351552cc3c335eb
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANTXR1 FBN1 PRNP	7.02e-04	190	41	3	f3ca94a31a35eed5fecf3c4b8c957e1bc4150158
ToppCell	10x3'2.3-week_14-16-Lymphocytic_NK\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	RASGRP1 SNAP91 PPP1R9A	7.02e-04	190	41	3	094efcde2b037ae509298abb8b2b1d52f9c86a45
ToppCell	droplet-Kidney-nan-3m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANTXR1 FBN1 PLA2G2E	7.02e-04	190	41	3	f61e21d53f2f7804ac6e40ab6c7f69838aa94d6a
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCAF11 PPP1R9A ADD3	7.02e-04	190	41	3	d26be9e1b676f750e716b91ebc3598fac3735612
ToppCell	droplet-Kidney-nan-3m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANTXR1 FBN1 PLA2G2E	7.02e-04	190	41	3	2abeb013bb83c578e67dcb985ba44ca63134950b
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	CACNA1D ANTXR1 FBN1	7.02e-04	190	41	3	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANTXR1 FBN1 PRNP	7.02e-04	190	41	3	c2cd1eb674162ee40502c3380b7245c85079c7ce
ToppCell	droplet-Lung-immune-endo-depleted-3m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM30B PRNP PPP1R9A	7.02e-04	190	41	3	aaf5f1c1ff7b1454f4e5dacfeb48e1c3627e3372
ToppCell	droplet-Lung-immune-endo-depleted-3m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM30B PRNP PPP1R9A	7.02e-04	190	41	3	a20123d5c6cb8c2f0dfd99bbfdb571a73c36234d
ToppCell	droplet-Lung-21m-Epithelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TMEM30B PRNP PPP1R9A	7.02e-04	190	41	3	50a8ba20f8153279387c335538bc52bf18ac1fc2
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D ANTXR1 FBN1	7.13e-04	191	41	3	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
Drug	PMME	PCYT1A PCYT1B	3.01e-06	2	40	2	CID000439436
Drug	isopentylamine	CRYGA CRYGB CRYGD SLC20A2	3.24e-06	58	40	4	CID000007894
Drug	pentosidine	CRYGA CRYGB CRYGD PNMT	4.81e-06	64	40	4	CID000119593
Drug	C05674	PCYT1A PCYT1B	9.02e-06	3	40	2	CID000440755
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NSD1 DNAJB12 RASGRP1 PRNP PCIF1	1.01e-05	165	40	5	5625_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NSD1 DNAJB12 RASGRP1 CUL7 PRNP	1.17e-05	170	40	5	5260_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NSD1 DNAJB12 RASGRP1 PRNP PCIF1	1.23e-05	172	40	5	2330_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NSD1 DNAJB12 TMEM30B RASGRP1 PRNP	1.27e-05	173	40	5	3243_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A	NSD1 DNAJB12 TMEM30B RASGRP1 PRNP	1.30e-05	174	40	5	5580_DN
Drug	Rifabutin [72559-06-9]; Down 200; 4.8uM; MCF7; HT_HG-U133A	DNAJB12 RASGRP1 PPP5C PRNP PCIF1	1.34e-05	175	40	5	3873_DN
Drug	trichostatin A ; Down 200; 1uM; MCF7; HT_HG-U133A_EA	NSD1 DNAJB12 TMEM30B RASGRP1 PRNP	1.38e-05	176	40	5	981_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NSD1 DNAJB12 TMEM30B RASGRP1 PRNP	1.38e-05	176	40	5	6932_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	DNAJB12 RASGRP1 TMEM62 CUL7 PRNP	1.42e-05	177	40	5	3177_DN
Drug	scriptaid; Down 200; 10uM; MCF7; HT_HG-U133A	DNAJB12 TMEM30B RASGRP1 SMG7 PRNP	1.50e-05	179	40	5	6901_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	DNAJB12 CACNA1D RASGRP1 TMEM62 PCIF1	1.54e-05	180	40	5	6454_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	NSD1 DNAJB12 TMEM30B RASGRP1 PRNP	1.58e-05	181	40	5	6951_DN
Drug	5182598; Up 200; 25uM; MCF7; HT_HG-U133A_EA	DNAJB12 CACNA1D PCYT1A SLC20A2 FECH	1.85e-05	187	40	5	868_UP
Drug	Imidurea [39236-46-9]; Down 200; 10.4uM; MCF7; HT_HG-U133A	PCYT1A TMEM62 SMG7 PPP5C SLC20A2	2.20e-05	194	40	5	3522_DN
Drug	Reserpinic acid hydrochloride; Down 200; 9.2uM; HL60; HT_HG-U133A	DNAJB12 FBN1 SMG7 F5 PCIF1	2.37e-05	197	40	5	2903_DN
Drug	Betonicine [515-25-3]; Down 200; 25.2uM; MCF7; HT_HG-U133A	DNAJB12 PCYT1A SMG7 PPP1R9A FECH	2.37e-05	197	40	5	6063_DN
Drug	fluphenazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A	DNAJB12 CUL7 SMG7 PPP5C SLC20A2	2.37e-05	197	40	5	5597_DN
Drug	rottlerin; Down 200; 10uM; MCF7; HT_HG-U133A_EA	RBM14 DNAJB12 TMEM62 CUL7 ADD3	2.43e-05	198	40	5	914_DN
Drug	Trimethylcolchicinic acid [3482-37-9]; Down 200; 11.6uM; MCF7; HT_HG-U133A	DNAJB12 TMEM62 CUL7 FECH PCIF1	2.49e-05	199	40	5	2802_DN
Drug	TMAEP	PCYT1A PCYT1B	3.00e-05	5	40	2	CID000151926
Drug	C11105	PCYT1A SAA4 PSMB4 PSMB5	3.98e-05	109	40	4	CID000443071
Drug	erythrose	CRYGA CRYGB CRYGD	4.74e-05	40	40	3	CID000094176
Drug	C20:1n-9	PCYT1A PCYT1B	6.28e-05	7	40	2	CID000142770
Drug	Choline	PCYT1A PCYT1B	6.28e-05	7	40	2	DB00122
Drug	ZNS 114-666	SAA4 TOPORS PRNP	8.75e-05	49	40	3	CID000409441
Drug	T1 p	CRYGA CRYGB CRYGD	9.87e-05	51	40	3	CID000657023
Drug	EGFR tyrosine kinase inhibitor 324674	PSMB4 PSMB5	1.08e-04	9	40	2	ctd:C561722
Drug	AC1L3TPS	NSD1 CACNA1D	1.34e-04	10	40	2	CID000121952
Drug	hydroxykynurenine	CRYGA CRYGB CRYGD	1.45e-04	58	40	3	CID000000089
Drug	C-eq	PCYT1A FBN1	1.64e-04	11	40	2	CID000137936
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NSD1 DNAJB12 RASGRP1 PRNP	1.89e-04	163	40	4	7453_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	DNAJB12 TMEM30B RASGRP1 PRNP	2.03e-04	166	40	4	7324_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NSD1 DNAJB12 RASGRP1 PRNP	2.03e-04	166	40	4	2268_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A	NSD1 DNAJB12 RASGRP1 PCIF1	2.08e-04	167	40	4	5217_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	DNAJB12 TMEM30B RASGRP1 PRNP	2.12e-04	168	40	4	6820_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	DNAJB12 RASGRP1 PPP5C PRNP	2.22e-04	170	40	4	4153_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	DNAJB12 TMEM30B RASGRP1 PRNP	2.22e-04	170	40	4	1050_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A_EA	NSD1 DNAJB12 RASGRP1 PRNP	2.27e-04	171	40	4	1000_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	DNAJB12 TMEM30B RASGRP1 PRNP	2.27e-04	171	40	4	5441_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NSD1 DNAJB12 RASGRP1 PRNP	2.27e-04	171	40	4	4954_DN
Drug	DB08515	PSMB4 PSMB5	2.32e-04	13	40	2	CID011840981
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	DNAJB12 TMEM30B RASGRP1 PRNP	2.32e-04	172	40	4	6993_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	DNAJB12 CUL7 PRNP PCIF1	2.32e-04	172	40	4	4344_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	DNAJB12 RASGRP1 CUL7 PRNP	2.38e-04	173	40	4	5987_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NSD1 DNAJB12 TMEM30B RASGRP1	2.38e-04	173	40	4	5336_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	NSD1 DNAJB12 RASGRP1 PRNP	2.43e-04	174	40	4	6579_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	DNAJB12 RASGRP1 SCAF11 PRNP	2.43e-04	174	40	4	1659_DN
Drug	HC toxin from Helminthosporium carbonum; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	NSD1 DNAJB12 RASGRP1 PRNP	2.43e-04	174	40	4	909_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	DNAJB12 TMEM30B RASGRP1 PRNP	2.43e-04	174	40	4	5945_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NSD1 DNAJB12 RASGRP1 PRNP	2.43e-04	174	40	4	6493_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	DNAJB12 RASGRP1 CUL7 PRNP	2.48e-04	175	40	4	5935_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A_EA	NSD1 DNAJB12 TMEM30B RASGRP1	2.48e-04	175	40	4	1014_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A_EA	DNAJB12 TMEM30B RASGRP1 PRNP	2.48e-04	175	40	4	1058_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	NSD1 DNAJB12 RASGRP1 PRNP	2.48e-04	175	40	4	7236_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	NSD1 TMEM30B RASGRP1 SMG7	2.48e-04	175	40	4	6891_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	DNAJB12 RASGRP1 TMEM62 PRNP	2.54e-04	176	40	4	2639_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	DNAJB12 TMEM30B RASGRP1 PRNP	2.54e-04	176	40	4	5976_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	DNAJB12 TMEM30B RASGRP1 PRNP	2.54e-04	176	40	4	1535_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A	NSD1 TMEM30B RASGRP1 PRNP	2.59e-04	177	40	4	1645_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	DNAJB12 RASGRP1 SCAF11 PRNP	2.59e-04	177	40	4	6972_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	DNAJB12 RASGRP1 SMG7 PRNP	2.59e-04	177	40	4	6434_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	DNAJB12 RASGRP1 PRNP PCIF1	2.59e-04	177	40	4	5308_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	DNAJB12 TMEM30B RASGRP1 PRNP	2.65e-04	178	40	4	1112_DN
Drug	Glidobactin A	PSMB4 PSMB5	2.70e-04	14	40	2	CID006439229
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	DNAJB12 TMEM30B RASGRP1 PPP5C	2.82e-04	181	40	4	7005_DN
Drug	Withaferin A [5119-48-2]; Down 200; 1uM; MCF7; HT_HG-U133A	ANTXR1 PPP5C ADD3 PCIF1	3.13e-04	186	40	4	3902_DN
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA	RBM14 TMEM62 INPP5F ADD3	3.26e-04	188	40	4	986_DN
Drug	bityrosine	CRYGA CRYGB CRYGD	3.36e-04	77	40	3	CID000107904
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A	NSD1 DNAJB12 CUL7 PCIF1	3.39e-04	190	40	4	1306_DN
Drug	Propantheline bromide [50-34-0]; Down 200; 9uM; MCF7; HT_HG-U133A	SMG7 PPP5C SLC20A2 PRNP	3.39e-04	190	40	4	3352_DN
Drug	Ethisterone [434-03-7]; Down 200; 12.8uM; MCF7; HT_HG-U133A	CACNA1D CUL7 F5 FECH	3.46e-04	191	40	4	3975_DN
Drug	Rilmenidine hemifumarate [54187-04-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A	ANTXR1 CUL7 SMG7 PPP1R9A	3.53e-04	192	40	4	6512_UP
Drug	Mephentermine hemisulfate [1212-72-2]; Down 200; 9.4uM; HL60; HT_HG-U133A	NSD1 SMG7 PPP5C PCIF1	3.60e-04	193	40	4	2563_DN
Drug	Dimenhydrinate [523-87-5]; Down 200; 8.6uM; MCF7; HT_HG-U133A	DNAJB12 SMG7 PPP5C SLC20A2	3.67e-04	194	40	4	5450_DN
Drug	Butirosin disulfate salt [51022-98-1]; Down 200; 5.4uM; MCF7; HT_HG-U133A	DNAJB12 ANTXR1 CUL7 PPP5C	3.67e-04	194	40	4	6779_DN
Drug	GSK-3 Inhibitor IX; Up 200; 0.5uM; MCF7; HT_HG-U133A	DNAJB12 TOPORS SLC20A2 PPP1R9A	3.67e-04	194	40	4	6589_UP
Drug	Althiazide [5588-16-9]; Down 200; 10.4uM; HL60; HT_HG-U133A	DNAJB12 PCYT1A SMG7 PRNP	3.67e-04	194	40	4	2527_DN
Drug	semustine; Up 200; 100uM; MCF7; HT_HG-U133A	PPP5C SLC20A2 PRNP FECH	3.67e-04	194	40	4	7487_UP
Drug	Ivermectin [70288-86-7]; Down 200; 4.6uM; MCF7; HT_HG-U133A	DNAJB12 PCYT1A CUL7 TOPORS	3.67e-04	194	40	4	2213_DN
Drug	Finasteride [98319-26-7]; Up 200; 10.8uM; PC3; HT_HG-U133A	DNAJB12 CRYGD CUL7 F5	3.75e-04	195	40	4	4300_UP
Drug	Clomipramine hydrochloride [17321-77-6]; Down 200; 11.4uM; MCF7; HT_HG-U133A	CACNA1D CUL7 SLC20A2 PCIF1	3.75e-04	195	40	4	6825_DN
Drug	Procarbazine hydrochloride [366-70-1]; Down 200; 15.6uM; HL60; HT_HG-U133A	NSD1 DNAJB12 SLC20A2 PCIF1	3.75e-04	195	40	4	2971_DN
Drug	Homatropine hydrobromide (R,S) [51-56-9]; Up 200; 11.2uM; MCF7; HT_HG-U133A	DNAJB12 PCYT1A FECH PCIF1	3.82e-04	196	40	4	1684_UP
Drug	Tinidazole [19387-91-8]; Up 200; 16.2uM; PC3; HT_HG-U133A	DNAJB12 PCYT1A SMG7 F5	3.82e-04	196	40	4	4548_UP
Drug	Methacycline hydrochloride [3963-95-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A	DNAJB12 PCYT1A CUL7 PPP5C	3.82e-04	196	40	4	4143_DN
Drug	Flurandrenolide [1524-88-5]; Down 200; 9.2uM; PC3; HT_HG-U133A	PCYT1A CUL7 PPP5C SLC20A2	3.82e-04	196	40	4	3679_DN
Drug	Ampyrone [83-07-8]; Up 200; 19.6uM; PC3; HT_HG-U133A	DNAJB12 SMG7 PPP5C PPP1R9A	3.82e-04	196	40	4	2086_UP
Drug	Nystatine [1400-61-9]; Up 200; 4.4uM; MCF7; HT_HG-U133A	CUL7 F5 SLC20A2 PPP1R9A	3.82e-04	196	40	4	4807_UP
Drug	Guanethidine sulfate [60-02-6]; Down 200; 13.4uM; MCF7; HT_HG-U133A	NSD1 CACNA1D SLC20A2 FECH	3.89e-04	197	40	4	3171_DN
Drug	Ofloxacin [82419-36-1]; Down 200; 11uM; MCF7; HT_HG-U133A	DNAJB12 ANTXR1 CUL7 SLC20A2	3.89e-04	197	40	4	2302_DN
Drug	Pyrithyldione [77-04-3]; Up 200; 24uM; MCF7; HT_HG-U133A	DNAJB12 FBN1 PPP5C PPP1R9A	3.89e-04	197	40	4	6801_UP
Drug	Dehydrocholic acid [81-23-2]; Up 200; 9.6uM; MCF7; HT_HG-U133A	PKP1 CACNA1D SNAP91 PPP1R9A	3.89e-04	197	40	4	5681_UP
Drug	Myricetin [529-44-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A	DNAJB12 CACNA1D SMG7 PPP1R9A	3.89e-04	197	40	4	3270_DN
Drug	Mexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; MCF7; HT_HG-U133A	DNAJB12 CACNA1D CUL7 FECH	3.89e-04	197	40	4	2324_DN
Drug	Deltaline [6836-11-9]; Down 200; 7.8uM; PC3; HT_HG-U133A	DNAJB12 PKP1 CUL7 SMG7	3.89e-04	197	40	4	3750_DN
Drug	Iopamidol [60166-93-0]; Up 200; 5.2uM; HL60; HT_HG-U133A	DNAJB12 PPP5C F5 PCYT1B	3.97e-04	198	40	4	2732_UP
Disease	surfeit locus protein 1 measurement	SAA4 F5	3.56e-05	7	39	2	EFO_0802105
Disease	cataract (implicated_via_orthology)	CRYGA CRYGD	1.16e-03	38	39	2	DOID:83 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
NYYRKYSAVRRDGSF	TMEM62	156	Q0P6H9
RASEQIYYENRQGYR	ANTXR1	126	Q9H6X2
RDLRNSGYRSAENAY	BPIFB4	116	P59827
RTLDNLGYRTGYAYR	ADD3	376	Q9UEY8
LSSSRNYDNYRRAYG	RASGRP1	331	O95267
YERPNYQGHQYFLRR	CRYGA	46	P11844
RYSRYLNEKAFSYRQ	SNAP91	126	O60641
ARYSGSYNDYLRAAQ	RBM14	646	Q96PK6
SNRRPYRQYYVEAFG	NSD1	356	Q96L73
LYYRDARSYNRFQIA	PSMB4	221	P28070
RDYDVYARRNLQRGY	PCYT1A	211	P49585
RDYDVYARRNLQRGY	PCYT1B	211	Q9Y5K3
SYLRGTLNRYSNFYN	CUL7	1416	Q14999
AQRQYHGDARALRYY	DXO	56	O77932
FRRNLGTYNRKYAHY	PLA2G2E	116	Q9NZK7
YEQPNYSGLQYFLRR	CRYGD	46	P07320
RENRPYYFNRFTNQS	PCIF1	56	Q9H4Z3
RRSLCYRNYYADNQT	FBN1	1691	P35555
RYTYQQRQDRRDNQG	DNAJB12	226	Q9NXW2
NFYQNNRRYGVSRDD	TMEM30B	116	Q3MIR4
YERPNYQGHQYFLRR	CRYGB	46	P07316
SSQRNRSNYYDAYQA	CLDN2	186	P57739
SSLNAIYRYYNQVGR	FECH	201	P22830
ADVQNYYSRRGRNSS	SCAF11	1156	Q99590
NHQNSNRYLYARGNY	SAA4	46	P35542
NRYLYARGNYDAAQR	SAA4	51	P35542
NRYYLNRFKDAYRQA	INPP5F	546	Q9Y2H2
NYRLLRRNNSYTCYT	SLC20A2	376	Q08357
SRQNYGYYSRYPGRN	CACNA1D	1861	Q01668
PTRYRQLEYNARNAY	PKP1	491	Q13835
YLRSNNGNRRNYYIA	F5	1571	P12259
RTNYQAYRSYLNREG	RFC1	376	P35251
YASQRNFYKRNLNRY	TEX48	91	A0A1B0GUV7
NAIYYGNRSLAYLRT	PPP5C	61	P53041
IARYRNQTSQAESYY	SMG7	161	Q92540
DRDQRYLTTYNQGYF	PPP1R32	336	Q7Z5V6
AYQRFEPRAYLRNNY	PNMT	26	P11086
GRNVYSSSRYDDYDR	SRSF10	101	O75494
TQYERESQAYYQRGS	PRNP	216	P04156
NRDRYYLRNNYGSRY	TOPORS	686	Q9NS56
RRAIYQATYRDAYSG	PSMB5	216	P28074
TNRAAAQYYLGNFRS	TTC4	121	O95801
YNVYRVRSRYNSDWG	PPP1R9A	401	Q9ULJ8