Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	4.48e-09	11	128	5	GO:0004523
GeneOntologyMolecularFunction	RNA-directed DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	1.91e-08	14	128	5	GO:0003964
GeneOntologyMolecularFunction	structural molecule activity	ERVK-6 TPR KRT2 SEPTIN5 DSP KRT31 KRT33A KRT33B NUMA1 ERVK-7 ACTN2 ERVK-10 NUP205 DST ERVK-8 ERVK-18 MACF1 TLN2 PLEC DMD KRT38 KRT37	5.04e-08	891	128	22	GO:0005198
GeneOntologyMolecularFunction	DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 REV3L ERVK-8 ERVK-11	1.44e-07	38	128	6	GO:0034061
GeneOntologyMolecularFunction	RNA stem-loop binding	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	1.88e-07	21	128	5	GO:0035613
GeneOntologyMolecularFunction	cytoskeletal protein binding	TPR KRT2 DLG5 KIF27 MYO1D CENPF SYNE1 NUMA1 ACTN2 PSTPIP2 SPAG8 OPA1 CORO2B DST PTPRN SYNE2 MID1 MACF1 TLN2 PLEC DMD MTUS2 KIFC1	4.65e-07	1099	128	23	GO:0008092
GeneOntologyMolecularFunction	RNA endonuclease activity, producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	3.70e-06	37	128	5	GO:0016891
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18	3.70e-06	37	128	5	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18	4.24e-06	38	128	5	GO:0070001
GeneOntologyMolecularFunction	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	1.11e-05	46	128	5	GO:0016893
GeneOntologyMolecularFunction	RNA endonuclease activity	ERVK-6 YBEY ERVK-7 ERVK-10 ERVK-8 ERVK-11	1.17e-05	79	128	6	GO:0004521
GeneOntologyMolecularFunction	endonuclease activity	ERVK-6 YBEY RBBP8 ERVK-7 ERVK-10 ERVK-8 ERVK-11	2.77e-05	136	128	7	GO:0004519
GeneOntologyMolecularFunction	microtubule binding	KIF27 CENPF NUMA1 SPAG8 OPA1 DST MID1 MACF1 MTUS2 KIFC1	3.00e-05	308	128	10	GO:0008017
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	ERVK-6 WAPL RBBP8 CHD2 ERVK-7 ERVK-10 REV3L ERVK-8 ERVK-11	4.92e-05	262	128	9	GO:0140097
GeneOntologyMolecularFunction	microtubule motor activity	DNHD1 DNAH3 KIF27 DYNC1H1 KIFC1	8.68e-05	70	128	5	GO:0003777
GeneOntologyMolecularFunction	tubulin binding	TPR KIF27 CENPF NUMA1 SPAG8 OPA1 DST MID1 MACF1 MTUS2 KIFC1	9.93e-05	428	128	11	GO:0015631
GeneOntologyMolecularFunction	actin filament binding	MYO1D SYNE1 ACTN2 PSTPIP2 CORO2B MACF1 TLN2 PLEC	1.09e-04	227	128	8	GO:0051015
GeneOntologyMolecularFunction	cytoskeletal motor activity	DNHD1 DNAH3 KIF27 MYO1D DYNC1H1 KIFC1	1.13e-04	118	128	6	GO:0003774
GeneOntologyMolecularFunction	nuclease activity	ERVK-6 YBEY RBBP8 ERVK-7 ERVK-10 REXO1 ERVK-8 ERVK-11	1.23e-04	231	128	8	GO:0004518
GeneOntologyMolecularFunction	structural constituent of cytoskeleton	KRT2 DSP KRT31 TLN2 PLEC DMD	1.92e-04	130	128	6	GO:0005200
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNHD1 DNAH3 DYNC1H1	1.96e-04	18	128	3	GO:0008569
GeneOntologyMolecularFunction	6-phosphofructo-2-kinase activity	PFKFB1 PFKFB3	2.43e-04	4	128	2	GO:0003873
GeneOntologyMolecularFunction	RNA nuclease activity	ERVK-6 YBEY ERVK-7 ERVK-10 ERVK-8 ERVK-11	2.46e-04	136	128	6	GO:0004540
GeneOntologyMolecularFunction	actin binding	MYO1D SYNE1 ACTN2 PSTPIP2 CORO2B DST SYNE2 MACF1 TLN2 PLEC DMD	2.64e-04	479	128	11	GO:0003779
GeneOntologyMolecularFunction	fructose-2,6-bisphosphate 2-phosphatase activity	PFKFB1 PFKFB3	4.03e-04	5	128	2	GO:0004331
GeneOntologyMolecularFunction	cytoskeleton-nuclear membrane anchor activity	SYNE1 SYNE2	4.03e-04	5	128	2	GO:0140444
GeneOntologyMolecularFunction	nucleotidyltransferase activity	ERVK-6 ERVK-7 ERVK-10 REV3L ERVK-8 ERVK-11	4.46e-04	152	128	6	GO:0016779
GeneOntologyMolecularFunction	dynein complex binding	TPR CENPF NUMA1	7.50e-04	28	128	3	GO:0070840
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNHD1 DNAH3 DYNC1H1	7.50e-04	28	128	3	GO:0051959
GeneOntologyMolecularFunction	phosphofructokinase activity	PFKFB1 PFKFB3	8.38e-04	7	128	2	GO:0008443
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNHD1 DNAH3 DYNC1H1	1.70e-03	37	128	3	GO:0045505
GeneOntologyMolecularFunction	sugar-phosphatase activity	PFKFB1 PFKFB3	1.77e-03	10	128	2	GO:0050308
GeneOntologyMolecularFunction	carbohydrate phosphatase activity	PFKFB1 PFKFB3	2.16e-03	11	128	2	GO:0019203
GeneOntologyMolecularFunction	dystroglycan binding	PLEC DMD	2.58e-03	12	128	2	GO:0002162
GeneOntologyMolecularFunction	structural constituent of muscle	ACTN2 PLEC DMD	2.63e-03	43	128	3	GO:0008307
GeneOntologyMolecularFunction	protein-membrane adaptor activity	TPR SYNE1 SYNE2	3.00e-03	45	128	3	GO:0043495
GeneOntologyMolecularFunction	vinculin binding	CORO2B DMD	3.04e-03	13	128	2	GO:0017166
GeneOntologyMolecularFunction	microtubule minus-end binding	NUMA1 MACF1	4.05e-03	15	128	2	GO:0051011
GeneOntologyBiologicalProcess	intermediate filament cytoskeleton organization	KRT2 DSP KRT31 KRT33A KRT33B DST MACF1 PLEC KRT38 KRT37	4.24e-10	99	124	10	GO:0045104
GeneOntologyBiologicalProcess	intermediate filament-based process	KRT2 DSP KRT31 KRT33A KRT33B DST MACF1 PLEC KRT38 KRT37	4.68e-10	100	124	10	GO:0045103
GeneOntologyBiologicalProcess	DNA integration	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	8.97e-09	13	124	5	GO:0015074
GeneOntologyBiologicalProcess	intermediate filament organization	KRT2 DSP KRT31 KRT33A KRT33B PLEC KRT38 KRT37	1.64e-08	75	124	8	GO:0045109
GeneOntologyBiologicalProcess	DNA synthesis involved in DNA repair	ERVK-6 ERVK-7 ERVK-10 REV3L ERVK-8 ERVK-11	4.17e-07	48	124	6	GO:0000731
GeneOntologyBiologicalProcess	DNA-templated DNA replication	ERVK-6 RBBP8 ERVK-7 ERVK-10 REV3L PURA ERVK-8 ERVK-11	1.23e-05	178	124	8	GO:0006261
GeneOntologyBiologicalProcess	DNA replication	ERVK-6 WAPL RBBP8 ERVK-7 ERVK-10 REV3L ESCO1 PURA ERVK-8 ERVK-11	1.94e-05	312	124	10	GO:0006260
GeneOntologyBiologicalProcess	nucleus localization	SYNE1 SYNE2 DMD DYNC1H1	1.40e-04	44	124	4	GO:0051647
GeneOntologyBiologicalProcess	RNA-templated DNA biosynthetic process	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11	1.45e-04	83	124	5	GO:0006278
GeneOntologyBiologicalProcess	microtubule-based movement	DNHD1 DNAH3 KIF27 OPA1 PGK2 DST PURA SYNE2 CFAP58 DYNC1H1 KIFC1	1.94e-04	493	124	11	GO:0007018
GeneOntologyBiologicalProcess	microtubule-based process	DNHD1 TPR DNAH3 KIF27 NUMA1 NUBP1 LYST OPA1 PGK2 DST PURA SYNE2 MID1 CFAP58 MACF1 DYNC1H1 KIFC1	2.00e-04	1058	124	17	GO:0007017
GeneOntologyBiologicalProcess	supramolecular fiber organization	KRT2 MYO1D DSP KRT31 KRT33A KRT33B NUMA1 ACTN2 PSTPIP2 LIMK1 CORO2B MID1 PLEC KRT38 KRT37 DYNC1H1	2.01e-04	957	124	16	GO:0097435
GeneOntologyBiologicalProcess	nuclear matrix organization	TPR SYNE1	2.13e-04	4	124	2	GO:0043578
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	KRT2 DNAH3 KIF27 DSP KRT31 KRT33A KRT33B CEP162 NUMA1 ACTN2 PSTPIP2 SPAG8 OPA1 DST AMOT MID1 MACF1 PLEC DMD KRT38 KRT37 MTUS2 DYNC1H1 KIFC1	6.10e-10	899	125	24	GO:0099513
GeneOntologyCellularComponent	supramolecular fiber	KRT2 DNAH3 KIF27 DSP KRT31 KRT33A KRT33B CEP162 SYNE1 NUMA1 ACTN2 PSTPIP2 SPAG8 OPA1 DST AMOT SYNE2 MID1 MACF1 PLEC DMD KRT38 KRT37 MTUS2 DYNC1H1 KIFC1	5.95e-09	1179	125	26	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	KRT2 DNAH3 KIF27 DSP KRT31 KRT33A KRT33B CEP162 SYNE1 NUMA1 ACTN2 PSTPIP2 SPAG8 OPA1 DST AMOT SYNE2 MID1 MACF1 PLEC DMD KRT38 KRT37 MTUS2 DYNC1H1 KIFC1	6.83e-09	1187	125	26	GO:0099081
GeneOntologyCellularComponent	intermediate filament cytoskeleton	KRT2 DSP KRT31 KRT33A KRT33B DST SYNE2 MACF1 PLEC DMD KRT38 KRT37	6.12e-08	263	125	12	GO:0045111
GeneOntologyCellularComponent	intermediate filament	KRT2 DSP KRT31 KRT33A KRT33B DST MACF1 PLEC DMD KRT38 KRT37	1.22e-07	227	125	11	GO:0005882
GeneOntologyCellularComponent	cell leading edge	MYO1D DUOX2 LIMK1 DST AMOT SYNE2 MACF1 TLN2 DMD ACAP2 FGD6 ARHGEF6	4.69e-05	500	125	12	GO:0031252
GeneOntologyCellularComponent	microtubule associated complex	DNHD1 TPR DNAH3 KIF27 MID1 DYNC1H1 KIFC1	5.26e-05	161	125	7	GO:0005875
GeneOntologyCellularComponent	cytoplasmic region	DNHD1 DNAH3 CENPF CEP162 NUMA1 SPAG8 OPA1 DST PURA DYNC1H1	6.22e-05	360	125	10	GO:0099568
GeneOntologyCellularComponent	microtubule	DNAH3 KIF27 CEP162 NUMA1 SPAG8 OPA1 DST MID1 MACF1 MTUS2 DYNC1H1 KIFC1	8.62e-05	533	125	12	GO:0005874
GeneOntologyCellularComponent	microtubule organizing center	DLG5 TTC28 CENPF CEP162 NUMA1 ANKS1B NUBP1 SPAG8 CROCC2 MID1 CFAP58 G6PD LRIF1 MTUS2 DYNC1H1 KIFC1	1.19e-04	919	125	16	GO:0005815
GeneOntologyCellularComponent	plasma membrane bounded cell projection cytoplasm	DNHD1 DNAH3 CENPF CEP162 SPAG8 OPA1 DST PURA DYNC1H1	1.24e-04	317	125	9	GO:0032838
GeneOntologyCellularComponent	cytoplasmic microtubule	CEP162 NUMA1 SPAG8 MID1 MTUS2 DYNC1H1	1.50e-04	133	125	6	GO:0005881
GeneOntologyCellularComponent	centrosome	TTC28 CENPF CEP162 NUMA1 ANKS1B NUBP1 CROCC2 MID1 CFAP58 G6PD LRIF1 MTUS2 DYNC1H1 KIFC1	2.10e-04	770	125	14	GO:0005813
GeneOntologyCellularComponent	dynein complex	DNHD1 TPR DNAH3 DYNC1H1	3.06e-04	54	125	4	GO:0030286
GeneOntologyCellularComponent	somatodendritic compartment	GRIPAP1 URI1 MYO1D SYNE1 NUMA1 ANKS1B ACTN2 KCNB2 OPA1 PTPRN PURA SEPTIN14 VPS35 OSBP2 PLEC DMD MDGA1 DYNC1H1	3.71e-04	1228	125	18	GO:0036477
GeneOntologyCellularComponent	spindle	TPR WAPL TTC28 CENPF CEP162 NUMA1 SPAG8 TMEM9 MID1 KIFC1	5.40e-04	471	125	10	GO:0005819
GeneOntologyCellularComponent	nuclear periphery	TPR CENPF NUMA1 NUP205 SF3B1 LRIF1	5.77e-04	171	125	6	GO:0034399
GeneOntologyCellularComponent	dendrite	GRIPAP1 URI1 MYO1D SYNE1 NUMA1 ANKS1B ACTN2 KCNB2 OPA1 PURA SEPTIN14 OSBP2 PLEC MDGA1	6.21e-04	858	125	14	GO:0030425
GeneOntologyCellularComponent	dendritic tree	GRIPAP1 URI1 MYO1D SYNE1 NUMA1 ANKS1B ACTN2 KCNB2 OPA1 PURA SEPTIN14 OSBP2 PLEC MDGA1	6.36e-04	860	125	14	GO:0097447
GeneOntologyCellularComponent	actin cytoskeleton	ACACA MYO1D SEPTIN5 BMF ACTN2 PSTPIP2 CORO2B DST AMOT MACF1 TLN2	6.89e-04	576	125	11	GO:0015629
GeneOntologyCellularComponent	mitotic spindle	TPR WAPL TTC28 NUMA1 TMEM9 KIFC1	1.33e-03	201	125	6	GO:0072686
GeneOntologyCellularComponent	cell-substrate junction	ACTN2 ITGB7 LIMK1 CORO2B DST SYNE2 TLN2 PLEC DMD	1.39e-03	443	125	9	GO:0030055
GeneOntologyCellularComponent	organelle outer membrane	SYNE1 BMF OPA1 SYNE2 TRAF3IP3 PLEC DMD	1.46e-03	279	125	7	GO:0031968
GeneOntologyCellularComponent	outer membrane	SYNE1 BMF OPA1 SYNE2 TRAF3IP3 PLEC DMD	1.52e-03	281	125	7	GO:0019867
GeneOntologyCellularComponent	inner dynein arm	DNHD1 DNAH3	1.55e-03	10	125	2	GO:0036156
GeneOntologyCellularComponent	cell cortex	MYO1D SEPTIN5 NUMA1 ACTN2 DST SEPTIN14 MACF1 DYNC1H1	1.77e-03	371	125	8	GO:0005938
GeneOntologyCellularComponent	nuclear membrane protein complex	SYNE1 SYNE2	1.88e-03	11	125	2	GO:0106083
GeneOntologyCellularComponent	nuclear membrane microtubule tethering complex	SYNE1 SYNE2	1.88e-03	11	125	2	GO:0106094
GeneOntologyCellularComponent	microtubule organizing center attachment site	SYNE1 SYNE2	1.88e-03	11	125	2	GO:0034992
GeneOntologyCellularComponent	hemidesmosome	DST PLEC	1.88e-03	11	125	2	GO:0030056
GeneOntologyCellularComponent	meiotic nuclear membrane microtubule tethering complex	SYNE1 SYNE2	1.88e-03	11	125	2	GO:0034993
GeneOntologyCellularComponent	anchoring junction	DLG5 DSP DUOX2 ACTN2 ITGB7 LIMK1 CORO2B DST AMOT SYNE2 TLN2 PLEC DMD ARHGEF6	2.11e-03	976	125	14	GO:0070161
GeneOntologyCellularComponent	Z disc	ACTN2 DST SYNE2 PLEC DMD	2.15e-03	151	125	5	GO:0030018
GeneOntologyCellularComponent	lamellipodium	LIMK1 AMOT SYNE2 DMD FGD6 ARHGEF6	2.63e-03	230	125	6	GO:0030027
GeneOntologyCellularComponent	fascia adherens	DSP TLN2	2.65e-03	13	125	2	GO:0005916
GeneOntologyCellularComponent	septin complex	SEPTIN5 SEPTIN14	3.08e-03	14	125	2	GO:0031105
GeneOntologyCellularComponent	septin ring	SEPTIN5 SEPTIN14	3.08e-03	14	125	2	GO:0005940
GeneOntologyCellularComponent	I band	ACTN2 DST SYNE2 PLEC DMD	3.24e-03	166	125	5	GO:0031674
GeneOntologyCellularComponent	sarcomere	SYNE1 ACTN2 DST SYNE2 PLEC DMD	3.88e-03	249	125	6	GO:0030017
GeneOntologyCellularComponent	contractile actin filament bundle	SEPTIN5 CORO2B DST AMOT	3.91e-03	107	125	4	GO:0097517
GeneOntologyCellularComponent	stress fiber	SEPTIN5 CORO2B DST AMOT	3.91e-03	107	125	4	GO:0001725
GeneOntologyCellularComponent	mitotic spindle midzone	TTC28 NUMA1	4.03e-03	16	125	2	GO:1990023
GeneOntologyCellularComponent	septin cytoskeleton	SEPTIN5 SEPTIN14	4.03e-03	16	125	2	GO:0032156
GeneOntologyCellularComponent	neuron projection cytoplasm	OPA1 DST PURA DYNC1H1	4.32e-03	110	125	4	GO:0120111
GeneOntologyCellularComponent	focal adhesion	ACTN2 ITGB7 LIMK1 CORO2B DST SYNE2 TLN2 PLEC	4.42e-03	431	125	8	GO:0005925
GeneOntologyCellularComponent	actomyosin	SEPTIN5 CORO2B DST AMOT	5.37e-03	117	125	4	GO:0042641
GeneOntologyCellularComponent	actin filament bundle	SEPTIN5 CORO2B DST AMOT	5.53e-03	118	125	4	GO:0032432
GeneOntologyCellularComponent	postsynaptic density	DLG5 ANKS1B ACTN2 DST PURA VPS35 MACF1 DMD	5.78e-03	451	125	8	GO:0014069
GeneOntologyCellularComponent	myofibril	SYNE1 ACTN2 DST SYNE2 PLEC DMD	6.04e-03	273	125	6	GO:0030016
GeneOntologyCellularComponent	filopodium	ACTN2 SYNE2 DMD DYNC1H1	6.40e-03	123	125	4	GO:0030175
HumanPheno	Abnormality of the Achilles tendon	SYNE1 OPA1 ARL6IP1 SYNE2 PLEC DMD	2.84e-05	64	49	6	HP:0005109
HumanPheno	Decreased cervical spine flexion due to contractures of posterior cervical muscles	SYNE1 SYNE2 PLEC	2.85e-05	7	49	3	HP:0004631
Domain	Spectrin_repeat	DSP SYNE1 ACTN2 DST SYNE2 MACF1 PLEC DMD	6.67e-12	29	116	8	IPR002017
Domain	SPEC	DSP SYNE1 ACTN2 DST SYNE2 MACF1 PLEC DMD	1.61e-11	32	116	8	SM00150
Domain	Spectrin/alpha-actinin	DSP SYNE1 ACTN2 DST SYNE2 MACF1 PLEC DMD	1.61e-11	32	116	8	IPR018159
Domain	ACTININ_2	SYNE1 ACTN2 DST SYNE2 MACF1 PLEC DMD	6.70e-11	23	116	7	PS00020
Domain	ACTININ_1	SYNE1 ACTN2 DST SYNE2 MACF1 PLEC DMD	6.70e-11	23	116	7	PS00019
Domain	Actinin_actin-bd_CS	SYNE1 ACTN2 DST SYNE2 MACF1 PLEC DMD	6.70e-11	23	116	7	IPR001589
Domain	Spectrin	SYNE1 ACTN2 DST SYNE2 MACF1 DMD	4.67e-09	23	116	6	PF00435
Domain	CH	SYNE1 ACTN2 DST SYNE2 MACF1 PLEC DMD ARHGEF6	6.52e-09	65	116	8	SM00033
Domain	CH	SYNE1 ACTN2 DST SYNE2 MACF1 PLEC DMD ARHGEF6	1.19e-08	70	116	8	PF00307
Domain	-	SYNE1 ACTN2 DST SYNE2 MACF1 PLEC DMD ARHGEF6	1.33e-08	71	116	8	1.10.418.10
Domain	CH	SYNE1 ACTN2 DST SYNE2 MACF1 PLEC DMD ARHGEF6	1.67e-08	73	116	8	PS50021
Domain	CH-domain	SYNE1 ACTN2 DST SYNE2 MACF1 PLEC DMD ARHGEF6	2.07e-08	75	116	8	IPR001715
Domain	-	DSP DST MACF1 PLEC	2.10e-08	6	116	4	3.90.1290.10
Domain	Plectin	DSP DST MACF1 PLEC	4.87e-08	7	116	4	PF00681
Domain	Plectin_repeat	DSP DST MACF1 PLEC	4.87e-08	7	116	4	IPR001101
Domain	PLEC	DSP DST MACF1 PLEC	4.87e-08	7	116	4	SM00250
Domain	Intermediate_filament_CS	KRT2 KRT31 KRT33A KRT33B KRT38 KRT37	2.57e-06	63	116	6	IPR018039
Domain	Filament	KRT2 KRT31 KRT33A KRT33B KRT38 KRT37	5.19e-06	71	116	6	SM01391
Domain	IF	KRT2 KRT31 KRT33A KRT33B KRT38 KRT37	5.64e-06	72	116	6	PS00226
Domain	Filament	KRT2 KRT31 KRT33A KRT33B KRT38 KRT37	6.11e-06	73	116	6	PF00038
Domain	Keratin_I	KRT31 KRT33A KRT33B KRT38 KRT37	7.58e-06	44	116	5	IPR002957
Domain	IF	KRT2 KRT31 KRT33A KRT33B KRT38 KRT37	7.73e-06	76	116	6	IPR001664
Domain	ARM-type_fold	USP34 WAPL LYST THADA SF3B1 PIK3C2A ANKAR VPS35 AP1G2 TTI1 LRBA	8.63e-06	339	116	11	IPR016024
Domain	Dynein_HC_stalk	DNHD1 DNAH3 DYNC1H1	8.08e-05	14	116	3	IPR024743
Domain	Dynein_heavy_dom-2	DNHD1 DNAH3 DYNC1H1	8.08e-05	14	116	3	IPR013602
Domain	DHC_N2	DNHD1 DNAH3 DYNC1H1	8.08e-05	14	116	3	PF08393
Domain	MT	DNHD1 DNAH3 DYNC1H1	8.08e-05	14	116	3	PF12777
Domain	DHC_fam	DNHD1 DNAH3 DYNC1H1	1.01e-04	15	116	3	IPR026983
Domain	Dynein_heavy	DNHD1 DNAH3 DYNC1H1	1.01e-04	15	116	3	PF03028
Domain	Dynein_heavy_dom	DNHD1 DNAH3 DYNC1H1	1.01e-04	15	116	3	IPR004273
Domain	KASH	SYNE1 SYNE2	2.28e-04	4	116	2	IPR012315
Domain	KASH	SYNE1 SYNE2	2.28e-04	4	116	2	PS51049
Domain	6Phosfructo_kin	PFKFB1 PFKFB3	2.28e-04	4	116	2	IPR013079
Domain	KASH	SYNE1 SYNE2	2.28e-04	4	116	2	SM01249
Domain	KASH	SYNE1 SYNE2	2.28e-04	4	116	2	PF10541
Domain	6Pfruct_kin	PFKFB1 PFKFB3	2.28e-04	4	116	2	IPR003094
Domain	6PF2K	PFKFB1 PFKFB3	2.28e-04	4	116	2	PF01591
Domain	P-loop_NTPase	DNHD1 DNAH3 DLG5 KIF27 MYO1D SEPTIN5 NUBP1 CHD2 PFKFB1 PFKFB3 OPA1 TRANK1 SEPTIN14 DYNC1H1 KIFC1	2.42e-04	848	116	15	IPR027417
Domain	PH_dom-like	ANKS1B ARHGEF12 LYST TLN2 OSBP2 LRBA PLCH1 ACAP2 FGD6 ARHGEF6	3.25e-04	426	116	10	IPR011993
Domain	PH_BEACH	LYST LRBA	5.64e-04	6	116	2	PF14844
Domain	GAR	DST MACF1	5.64e-04	6	116	2	PS51460
Domain	GAS2	DST MACF1	5.64e-04	6	116	2	PF02187
Domain	-	DST MACF1	5.64e-04	6	116	2	3.30.920.20
Domain	GAS_dom	DST MACF1	5.64e-04	6	116	2	IPR003108
Domain	GAS2	DST MACF1	5.64e-04	6	116	2	SM00243
Domain	-	ANKS1B ANKRD36B TRANK1 ANKAR NFKBIL1 ANKRD36 ACAP2	9.13e-04	248	116	7	1.25.40.20
Domain	ANK	ANKS1B ANKRD36B TRANK1 ANKAR NFKBIL1 ANKRD36 ACAP2	9.80e-04	251	116	7	SM00248
Domain	ANK_REPEAT	ANKS1B ANKRD36B TRANK1 ANKAR NFKBIL1 ANKRD36 ACAP2	1.03e-03	253	116	7	PS50088
Domain	PH-BEACH_dom	LYST LRBA	1.04e-03	8	116	2	IPR023362
Domain	-	LYST LRBA	1.04e-03	8	116	2	2.30.29.40
Domain	PH_BEACH	LYST LRBA	1.04e-03	8	116	2	PS51783
Domain	Ankyrin_rpt-contain_dom	ANKS1B ANKRD36B TRANK1 ANKAR NFKBIL1 ANKRD36 ACAP2	1.05e-03	254	116	7	IPR020683
Domain	ANK_REP_REGION	ANKS1B ANKRD36B TRANK1 ANKAR NFKBIL1 ANKRD36 ACAP2	1.05e-03	254	116	7	PS50297
Domain	Prefoldin	TPR URI1 DSP AMOT	1.05e-03	72	116	4	IPR009053
Domain	Ankyrin_rpt	ANKS1B ANKRD36B TRANK1 ANKAR NFKBIL1 ANKRD36 ACAP2	1.26e-03	262	116	7	IPR002110
Domain	BEACH	LYST LRBA	1.34e-03	9	116	2	PS50197
Domain	Beach	LYST LRBA	1.34e-03	9	116	2	PF02138
Domain	-	LYST LRBA	1.34e-03	9	116	2	1.10.1540.10
Domain	Beach	LYST LRBA	1.34e-03	9	116	2	SM01026
Domain	PG/BPGM_mutase_AS	PFKFB1 PFKFB3	1.34e-03	9	116	2	IPR001345
Domain	BEACH_dom	LYST LRBA	1.34e-03	9	116	2	IPR000409
Domain	PGAM	PFKFB1 PFKFB3	1.67e-03	10	116	2	SM00855
Domain	PG_MUTASE	PFKFB1 PFKFB3	1.67e-03	10	116	2	PS00175
Domain	-	DNHD1 DNAH3 DLG5 SEPTIN5 NUBP1 CHD2 PFKFB1 PFKFB3 OPA1 TRANK1 SEPTIN14 DYNC1H1	2.33e-03	746	116	12	3.40.50.300
Domain	His_Pase_superF_clade-1	PFKFB1 PFKFB3	2.42e-03	12	116	2	IPR013078
Domain	His_Phos_1	PFKFB1 PFKFB3	2.42e-03	12	116	2	PF00300
Domain	G_SEPTIN_dom	SEPTIN5 SEPTIN14	2.85e-03	13	116	2	IPR030379
Domain	Septin	SEPTIN5 SEPTIN14	2.85e-03	13	116	2	PF00735
Domain	G_SEPTIN	SEPTIN5 SEPTIN14	2.85e-03	13	116	2	PS51719
Domain	-	ANKS1B ARHGEF12 TLN2 OSBP2 PLCH1 ACAP2 FGD6 ARHGEF6	3.06e-03	391	116	8	2.30.29.30
Domain	EFh	DUOX2 ACTN2 DST MACF1 PLCH1	3.07e-03	158	116	5	SM00054
Domain	Dynein_heavy_chain_D4_dom	DNAH3 DYNC1H1	3.31e-03	14	116	2	IPR024317
Domain	ATPase_dyneun-rel_AAA	DNAH3 DYNC1H1	3.31e-03	14	116	2	IPR011704
Domain	AAA_8	DNAH3 DYNC1H1	3.31e-03	14	116	2	PF12780
Domain	Septin	SEPTIN5 SEPTIN14	3.31e-03	14	116	2	IPR016491
Domain	AAA_5	DNAH3 DYNC1H1	3.31e-03	14	116	2	PF07728
Domain	-	DUOX2 ACTN2 DST MACF1 DMD PLCH1	5.81e-03	261	116	6	1.10.238.10
Pathway	REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE	KRT2 DSP KRT31 KRT33A KRT33B KRT38 KRT37	1.25e-05	129	85	7	M27649
Pathway	REACTOME_GLUCOSE_METABOLISM	TPR PFKFB1 PFKFB3 PGK2 NUP205	1.34e-04	82	85	5	MM15394
Pathway	REACTOME_GLUCOSE_METABOLISM	TPR PFKFB1 PFKFB3 PGK2 NUP205	1.59e-04	85	85	5	M1870
Pathway	REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE	KRT2 DSP KRT31 KRT33A KRT33B	1.77e-04	87	85	5	MM15351
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	KRT2 MYO1D CENPF DSP KRT31 KRT33A RBBP8 KRT33B SYNE1 MAFA NUMA1 ANKS1B DUOX2 SRP72 CHD2 ACTN2 LYST PGK2 NUP205 SF3B1 DST SYNE2 VPS35 MACF1 PLEC DMD PLCH1 ZBTB11 CAVIN2	8.45e-14	1442	130	29	35575683
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	DNHD1 TPR DSP SYNE1 NUMA1 SF3B1 DST VPS35 MACF1 PLEC LRBA DMD PLCH1	5.41e-12	234	130	13	36243803
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TET2 TPR USP34 ACACA TTC28 CENPF DSP RBBP8 GTF3C4 DST AMOT RABEP1 PLEC LRBA ZBTB11	5.91e-11	418	130	15	34709266
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	TET2 USP34 WAPL TTC28 DSP SYNE1 ANKS1B PSMD4 REV3L GTF3C4 LIMK1 CORO2B SF3B1 DST RABEP1 SGSM2 MACF1 TLN2 ANKRD36 PLEC LRBA ZBTB11 MTUS2 DYNC1H1	7.27e-11	1285	130	24	35914814
Pubmed	Characterization of a 190-kilobase pair domain of human type I hair keratin genes.	KRT31 KRT33A KRT33B KRT38 KRT37	8.41e-11	9	130	5	9756910
Pubmed	Human hair keratins.	KRT31 KRT33A KRT33B KRT38 KRT37	8.41e-11	9	130	5	7686952
Pubmed	The catalog of human hair keratins. I. Expression of the nine type I members in the hair follicle.	KRT31 KRT33A KRT33B KRT38 KRT37	1.68e-10	10	130	5	10391933
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	TPR USP34 ACACA MYO1D CENPF DSP NUMA1 SRP72 CHD2 NUP205 SF3B1 DST SYNE2 MACF1 PLEC ZBTB11 DYNC1H1	4.16e-10	653	130	17	22586326
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	DNHD1 TPR WAPL KIF27 ACACA MYO1D CENPF DSP SYNE1 NUMA1 DUOX2 SRP72 PSMD4 OPA1 NUP205 THADA SF3B1 ADSL AMOT VPS35 TLN2 G6PD DYNC1H1 KIFC1	5.82e-10	1425	130	24	30948266
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	DNHD1 DLG5 SYNE1 ARHGEF12 ANKRD36B DST SYNE2 ANKRD36 PLEC DMD	2.42e-09	187	130	10	26460568
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	KRT2 MYO1D SEPTIN5 DSP SYNE1 ANKS1B ARHGEF12 SRP72 ACTN2 OPA1 CORO2B SF3B1 DST AMOT PURA VPS35 MACF1 TLN2 PLEC DMD PLCH1 MTUS2 DYNC1H1	3.39e-09	1431	130	23	37142655
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	TPR GRIPAP1 NUMA1 PSMD4 DST RABEP1 MACF1 PLEC ACAP2 G6PD DYNC1H1 CAVIN2	1.22e-08	360	130	12	33111431
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	GRIPAP1 CENPF SYNE1 ACTN2 DST MACF1 DMD DYNC1H1	1.81e-08	120	130	8	31413325
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	TET2 DLG5 ACACA TTC28 DSP CEP162 LYST LIMK1 DST PIK3C2A AMOT RABEP1 SYNE2 MACF1 PLEC PLCH1 FGD6	2.52e-08	861	130	17	36931259
Pubmed	Functional specialization of beta-arrestin interactions revealed by proteomic analysis.	DNAH3 ACACA CENPF ARHGEF12 PFKFB3 SF3B1 PIK3C2A VPS35 DMD DYNC1H1 ARHGEF6	3.37e-08	317	130	11	17620599
Pubmed	Widespread macromolecular interaction perturbations in human genetic disorders.	CYP1A1 KRT2 KRT31 KRT33B ACTN2 ARL6IP1 PTPRN MID1 RNF41 TRAF3IP3 DMD KRT38 MTUS2 CCDC136	5.06e-08	590	130	14	25910212
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	WAPL ACACA CENPF NUMA1 CHD2 MAGT1 OPA1 GTF3C4 TRANK1 CROCC2 VPS35 LRBA G6PD	5.08e-08	497	130	13	36774506
Pubmed	BPAG1 isoform-b: complex distribution pattern in striated and heart muscle and association with plectin and alpha-actinin.	ACTN2 DST PLEC	5.10e-08	3	130	3	19932097
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	CENPF SYNE1 REV3L DST SYNE2 RASGEF1C CFAP58 MACF1 DMD	6.10e-08	197	130	9	20811636
Pubmed	The human type I keratin gene family: characterization of new hair follicle specific members and evaluation of the chromosome 17q21.2 gene domain.	KRT33A KRT33B KRT38 KRT37	9.01e-08	12	130	4	15617563
Pubmed	A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.	DSP NUMA1 ARHGEF12 CHD2 ESCO1 SF3B1 DST SGSM2 PLEC DYNC1H1	1.27e-07	284	130	10	29459677
Pubmed	New consensus nomenclature for mammalian keratins.	KRT2 KRT31 KRT33A KRT33B KRT38 KRT37	1.39e-07	63	130	6	16831889
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	TPR KRT2 WAPL ACACA DSP NUMA1 PSMD4 CHD2 GTF3C4 NUP205 SF3B1 DST ADSL PIK3C2A VPS35 AP1G2 MACF1 PLEC G6PD DYNC1H1	1.56e-07	1353	130	20	29467282
Pubmed	Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.	ERVK-6 ERVK-7 ERVK-10	2.04e-07	4	130	3	10469592
Pubmed	Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.	DST MACF1 DMD	2.04e-07	4	130	3	8954775
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	DSP SYNE1 SRP72 CHD2 ACTN2 DST PIK3C2A AMOT RABEP1 SYNE2 MACF1 PLEC	3.99e-07	497	130	12	23414517
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	USP34 WAPL DSP DST SYNE2 VPS35 MACF1 RNF41 DMD DYNC1H1	4.02e-07	322	130	10	26514267
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	TPR DLG5 TTC28 DSP NUMA1 ARHGEF12 SRP72 MAGT1 OPA1 DST MACF1 LRBA PLCH1 DYNC1H1	4.60e-07	708	130	14	39231216
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-6 ERVK-7 ERVK-18	5.08e-07	5	130	3	12629516
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TPR SEPTIN5 CENPF SYNE1 NUMA1 ANKS1B ARHGEF12 OPA1 SF3B1 DST RABEP1 PURA SYNE2 MACF1 TLN2 DYNC1H1	6.73e-07	963	130	16	28671696
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	TET2 WAPL DSP PFKFB3 ESCO1 GTF3C4 SF3B1 PLEC DYNC1H1	9.26e-07	272	130	9	31010829
Pubmed	Whn and mHa3 are components of the genetic hierarchy controlling hair follicle differentiation.	KRT31 KRT33A KRT33B	1.01e-06	6	130	3	10559501
Pubmed	TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton.	SYNE1 SYNE2 PLEC	1.01e-06	6	130	3	18827015
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	USP34 CENPF RBBP8 ETV6 PSMD4 GTF3C4 CCNC MSANTD3 SF3B1 CAVIN2 KIFC1	1.17e-06	453	130	11	29656893
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	SEPTIN5 SYNE1 ANKS1B KCNB2 OPA1 PURA MACF1 TLN2 DYNC1H1	1.21e-06	281	130	9	28706196
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	TPR KRT2 URI1 ACACA DSP KRT31 KRT33A NUMA1 NUBP1 SRP72 OPA1 SF3B1 ADSL SYNE2 VPS35 MACF1 PLEC G6PD DYNC1H1	1.39e-06	1415	130	19	28515276
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	ACACA MYO1D DSP KRT31 KRT33A KRT33B CEP162 PSMD4 PFKFB3 OPA1 NUP205 SF3B1 RABEP1 PURA VPS35 NFKBIL1 LRBA DYNC1H1	1.48e-06	1284	130	18	17353931
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	TPR MYO1D CENPF DSP KRT33B SYNE1 NUMA1 NUP205 SF3B1 DST AMOT SYNE2 MACF1 PLEC DYNC1H1 KIFC1	1.50e-06	1024	130	16	24711643
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18 ERVK-11	1.51e-06	94	130	6	21542922
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	CENPF SYNE1 DST MACF1 DMD CCDC136 DYNC1H1	1.71e-06	151	130	7	17043677
Pubmed	Desmoplakin and talin2 are novel mRNA targets of fragile X-related protein-1 in cardiac muscle.	DSP ACTN2 TLN2	1.77e-06	7	130	3	21659647
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	ACACA SYNE1 REV3L ESCO1 AMOT MACF1 PLEC	1.79e-06	152	130	7	34299191
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	TPR WAPL KIF27 DSP SRP72 PSTPIP2 SF3B1 PURA MACF1 TLN2 PLEC DYNC1H1	2.07e-06	582	130	12	20467437
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	USP34 TTC28 SYNE1 DST AMOT SYNE2 MACF1 TLN2	2.24e-06	225	130	8	12168954
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	USP34 MYO1D SYNE1 DST MACF1 MTUS2	2.30e-06	101	130	6	9872452
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	USP34 KRT2 DSP MAFA PSMD4 CHD2 MAGT1 GTF3C4 NUP205 SF3B1 ARL6IP1 TMEM9 AMOT VPS35 RBAK PLEC ILVBL	2.67e-06	1203	130	17	29180619
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	TPR SEPTIN5 CENPF KRT31 NUMA1 DST SYNE2 TTI1 MACF1 TLN2 ILVBL	2.92e-06	498	130	11	36634849
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	TPR KRT2 DSP SYNE1 SRP72 OPA1 SF3B1 DST ADSL MACF1 PLEC DMD G6PD DYNC1H1	3.59e-06	844	130	14	25963833
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	DNAH3 ACACA CENPF DSP YBEY CHD2 REV3L ESCO1 NUP205 DST AMOT ZBTB11 DYNC1H1	4.16e-06	736	130	13	29676528
Pubmed	Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly.	DSP DST PLEC	4.22e-06	9	130	3	12482924
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TET2 USP34 DLG5 WAPL CEP162 NUP205 TRANK1 DST ARL6IP1 AMOT ACAP2	5.18e-06	529	130	11	14621295
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	TPR DLG5 CENPF DSP SF3B1 PLEC DYNC1H1 KIFC1	5.79e-06	256	130	8	33397691
Pubmed	CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.	DLG5 PSMD4 VPS35 RNF41 PLEC G6PD DYNC1H1	5.88e-06	182	130	7	31067453
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	DLG5 TTC28 CEP162 CCNC DST ADSL AMOT LRBA ACAP2 LRIF1 ARHGEF6 KIFC1	5.89e-06	645	130	12	25281560
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	TPR WAPL ACACA TTC28 DSP NUMA1 GTF3C4 AMOT RABEP1 LRBA DYNC1H1	7.35e-06	549	130	11	38280479
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	TPR NUMA1 PSMD4 PFKFB3 NUP205 SF3B1 DST PIK3C2A MACF1 PLEC KRT38 CAVIN2	7.43e-06	660	130	12	32780723
Pubmed	Charting the molecular network of the drug target Bcr-Abl.	KRT2 ACACA MYO1D KRT33B PSTPIP2 KRT38 KRT37 DYNC1H1	7.66e-06	266	130	8	19380743
Pubmed	Interaction of the bullous pemphigoid antigen 1 (BP230) and desmoplakin with intermediate filaments is mediated by distinct sequences within their COOH terminus.	DSP DST PLEC	8.24e-06	11	130	3	12802069
Pubmed	Agrin has a pathological role in the progression of oral cancer.	DLG5 SYNE1 SRP72 PSMD4 ACTN2 DMD ACAP2	9.87e-06	197	130	7	29872149
Pubmed	Does SF3B1/TET2 Double Mutation Portend Better or Worse Prognosis Than Isolated SF3B1 or TET2 Mutation?	TET2 SF3B1	1.39e-05	2	130	2	30587503
Pubmed	Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.	SYNE1 SYNE2	1.39e-05	2	130	2	11792814
Pubmed	Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.	DST MACF1	1.39e-05	2	130	2	11002341
Pubmed	Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.	SYNE1 SYNE2	1.39e-05	2	130	2	24931616
Pubmed	5-formylcytosine and 5-hydroxymethyluracil as surrogate markers of TET2 and SF3B1 mutations in myelodysplastic syndrome, respectively.	TET2 SF3B1	1.39e-05	2	130	2	31488558
Pubmed	Mechanism of spindle pole organization and instability in human oocytes.	NUMA1 KIFC1	1.39e-05	2	130	2	35143306
Pubmed	Differential expression of type I hair keratins.	KRT33A KRT33B	1.39e-05	2	130	2	1689759
Pubmed	Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.	SYNE1 SYNE2	1.39e-05	2	130	2	22768332
Pubmed	NuMA recruits dynein activity to microtubule minus-ends at mitosis.	NUMA1 DYNC1H1	1.39e-05	2	130	2	29185983
Pubmed	Cardiac-specific PFKFB3 overexpression prevents diabetic cardiomyopathy via enhancing OPA1 stabilization mediated by K6-linked ubiquitination.	PFKFB3 OPA1	1.39e-05	2	130	2	38777955
Pubmed	Spectrin-like repeats from dystrophin and alpha-actinin-2 are not functionally interchangeable.	ACTN2 DMD	1.39e-05	2	130	2	12140183
Pubmed	Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.	SYNE1 SYNE2	1.39e-05	2	130	2	17267447
Pubmed	Nesprins: tissue-specific expression of epsilon and other short isoforms.	SYNE1 SYNE2	1.39e-05	2	130	2	24718612
Pubmed	Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.	SYNE1 SYNE2	1.39e-05	2	130	2	24586179
Pubmed	A novel human type I hair keratin gene: evidence for two keratin hHa3 isoforms.	KRT33A KRT33B	1.39e-05	2	130	2	7565656
Pubmed	Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.	SYNE1 SYNE2	1.39e-05	2	130	2	17761684
Pubmed	Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.	SYNE1 SYNE2	1.39e-05	2	130	2	31578382
Pubmed	Physiologic Expression of Sf3b1(K700E) Causes Impaired Erythropoiesis, Aberrant Splicing, and Sensitivity to Therapeutic Spliceosome Modulation.	TET2 SF3B1	1.39e-05	2	130	2	27622333
Pubmed	Interferon-alpha-induced endogenous superantigen. a model linking environment and autoimmunity.	ERVK-6 ERVK-18	1.39e-05	2	130	2	11672541
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	DLG5 ACACA TTC28 ARHGEF12 DST RABEP1 MACF1	1.45e-05	209	130	7	36779422
Pubmed	Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.	TPR KRT2 ACACA KRT31 NUP205 SF3B1 VPS35 MACF1 PLEC LRBA G6PD DYNC1H1	1.47e-05	707	130	12	19738201
Pubmed	Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant.	KRT2 ACACA DSP KRT31 KRT33B SF3B1 MACF1 PLEC DMD DYNC1H1	1.60e-05	488	130	10	31324722
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	TPR CENPF DSP NUMA1 SRP72 PSMD4 SF3B1 VPS35 PLEC KIFC1	1.78e-05	494	130	10	26831064
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	TPR KRT2 DLG5 MYO1D CENPF DSP NUMA1 SRP72 MAGT1 GTF3C4 NUP205 SF3B1 DST PLEC DYNC1H1 KIFC1	1.96e-05	1257	130	16	36526897
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	TPR KIF27 SEPTIN5 CENPF SRP72 PURA LRBA DMD	2.01e-05	304	130	8	32235678
Pubmed	Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.	KRT31 KRT33B BMF ETV6 ACTN2 PSTPIP2 ARL6IP1 PTPRN DMD KRT38 MTUS2 CCDC136	2.37e-05	742	130	12	26871637
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	TPR GRIPAP1 ACACA SEPTIN5 DSP ANKS1B PSMD4 KCNB2 OPA1 SF3B1 RABEP1 PURA MACF1 TLN2 PLEC	2.45e-05	1139	130	15	36417873
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	WAPL ACACA DSP SYNE1 NUP205 SF3B1 SYNE2 DMD ACAP2 G6PD ILVBL DYNC1H1	2.76e-05	754	130	12	35906200
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	KRT2 DSP KRT31 YBEY KRT33B SRP72 PSMD4 CHD2 SF3B1 AMOT PURA MACF1 KRT38 KRT37 DYNC1H1	2.82e-05	1153	130	15	29845934
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	USP34 GRIPAP1 ACACA NUBP1 SRP72 PSMD4 GTF3C4 NUP205 ADSL RABEP1 VPS35 TTI1 MACF1 PLEC LRBA G6PD DYNC1H1	3.13e-05	1455	130	17	22863883
Pubmed	Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy.	KRT2 KRT31 KRT33A KRT33B CFAP58	3.14e-05	96	130	5	23580065
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	TPR MYO1D DSP KRT33A PSMD4 ACTN2 THADA TTI1 PLEC LRBA DYNC1H1	3.34e-05	647	130	11	26618866
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	GRIPAP1 URI1 MAGT1 OPA1 GTF3C4 NUP205 THADA AMOT RABEP1 NFKBIL1 TTI1 PLEC ACAP2 FGD6 DYNC1H1 ARHGEF6	3.56e-05	1321	130	16	27173435
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	TPR WAPL ACACA DSP RBBP8 NUMA1 REXO1 GTF3C4 SF3B1 TLN2 PLEC ARHGEF6	3.56e-05	774	130	12	15302935
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	GRIPAP1 WAPL NUMA1 SF3B1 DST PURA MACF1 DMD G6PD DYNC1H1	3.67e-05	538	130	10	28524877
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	USP34 KRT2 GRIPAP1 ACACA TTC28 CEP162 THADA SF3B1 DST AMOT LRBA DYNC1H1	3.70e-05	777	130	12	35844135
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	TET2 KRT2 ACACA DSP OPA1 GTF3C4 SF3B1 PLEC ZBTB11 G6PD ILVBL	3.73e-05	655	130	11	35819319
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	CENPF NUMA1 GTF3C4 NR2F2 DST MACF1 PLEC DYNC1H1	3.75e-05	332	130	8	37433992
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	TPR WAPL NUMA1 GTF3C4 SF3B1 TTI1 PLEC DYNC1H1	3.75e-05	332	130	8	32786267
Pubmed	Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.	ERVK-10 ERVK-18 ERVK-11	4.00e-05	18	130	3	18664271
Pubmed	Motor protein KIFC5A interacts with Nubp1 and Nubp2, and is implicated in the regulation of centrosome duplication.	NUBP1 KIFC1	4.15e-05	3	130	2	16638812
Interaction	GAN interactions	DNHD1 DLG5 KRT31 KRT33B SYNE1 ARHGEF12 ANKRD36B DST SYNE2 ANKRD36 PLEC DMD KRT38 KRT37	6.66e-10	253	126	14	int:GAN
Interaction	KRT8 interactions	KRT2 DLG5 GRIPAP1 DSP KRT31 KRT33A KRT33B CEP162 ARHGEF12 NUP205 THADA RABEP1 PLEC DMD KRT38 KRT37	1.66e-08	441	126	16	int:KRT8
Interaction	PHF21A interactions	TPR USP34 GRIPAP1 ACACA TTC28 CENPF DSP RBBP8 DST AMOT RABEP1 PLEC LRBA ZBTB11	3.25e-08	343	126	14	int:PHF21A
Interaction	KDM1A interactions	TET2 TPR USP34 DLG5 GRIPAP1 ACACA TTC28 CENPF DSP KRT31 RBBP8 KRT33B CEP162 ESCO1 GTF3C4 DST AMOT RABEP1 AP1G2 PLEC LRBA KRT38	8.35e-08	941	126	22	int:KDM1A
Interaction	FAM50B interactions	GRIPAP1 KRT31 ACTN2 CCNC RABEP1 MID1 CCDC136	2.47e-07	69	126	7	int:FAM50B
Interaction	RCOR1 interactions	TPR USP34 GRIPAP1 ACACA TTC28 CENPF DSP RBBP8 NUMA1 DST AMOT RABEP1 PLEC LRBA ZBTB11	4.77e-07	494	126	15	int:RCOR1
Interaction	TTC23 interactions	GRIPAP1 DSP KRT31 CHD2 SPAG8 SF3B1 DST SGSM2 MTUS2 DYNC1H1	7.52e-07	208	126	10	int:TTC23
Interaction	KCNA3 interactions	DNHD1 TPR DLG5 MYO1D TTC28 DSP NUMA1 ARHGEF12 SRP72 CHD2 MAGT1 OPA1 DST MID1 MACF1 TLN2 LRBA PLCH1 DYNC1H1	1.99e-06	871	126	19	int:KCNA3
Interaction	AQP1 interactions	KRT31 KRT33B BMF AMOT RBAK KRT37 MTUS2 CCDC136	2.51e-06	138	126	8	int:AQP1
Interaction	SIRT7 interactions	TPR USP34 ACACA MYO1D CENPF DSP NUMA1 SRP72 CHD2 NUP205 SF3B1 DST SYNE2 MACF1 PLEC ZBTB11 DYNC1H1	3.94e-06	744	126	17	int:SIRT7
Interaction	YWHAH interactions	TET2 DLG5 TTC28 DSP CEP162 PFKFB3 LYST PTH1R DST PIK3C2A AMOT RABEP1 PURA SYNE2 MACF1 PLEC LRBA PLCH1 FGD6 G6PD ARHGEF6	4.57e-06	1102	126	21	int:YWHAH
Interaction	TEDC2 interactions	DSP NUMA1 ARHGEF12 ESCO1 SF3B1 DST SGSM2 PLEC DYNC1H1	6.00e-06	206	126	9	int:TEDC2
Interaction	USP7 interactions	TET2 DNHD1 TPR MANBA DSP SYNE1 MAFA NUMA1 ETV6 PSMD4 OPA1 CORO2B SF3B1 DST VPS35 MACF1 PLEC LRBA DMD PLCH1 MDGA1 DYNC1H1 ARHGEF6	6.12e-06	1313	126	23	int:USP7
Interaction	C1orf216 interactions	KRT31 KRT33B AMOT KRT38 MTUS2 CCDC136	6.40e-06	73	126	6	int:C1orf216
Interaction	YWHAG interactions	TET2 DLG5 TTC28 DSP KRT31 KRT33B CEP162 PFKFB3 LYST DST PIK3C2A AMOT RABEP1 PURA SYNE2 MACF1 LRBA PLCH1 FGD6 G6PD DYNC1H1 ARHGEF6	9.11e-06	1248	126	22	int:YWHAG
Interaction	KCTD13 interactions	KRT2 MYO1D SEPTIN5 DSP SYNE1 ANKS1B ARHGEF12 SRP72 ACTN2 OPA1 CORO2B SF3B1 DST AMOT PURA VPS35 MACF1 TLN2 PLEC DMD PLCH1 MTUS2 DYNC1H1	1.61e-05	1394	126	23	int:KCTD13
Interaction	DISC1 interactions	GRIPAP1 SYNE1 ACTN2 DST AMOT MACF1 DMD KRT38 KRT37 CCDC136 DYNC1H1 MXD1	1.62e-05	429	126	12	int:DISC1
Interaction	CEP152 interactions	DLG5 TTC28 DSP ETV6 ADSL AMOT KRT38 KRT37	1.71e-05	179	126	8	int:CEP152
Interaction	EPHA1 interactions	USP34 MYO1D SYNE1 OPA1 NR2F2 NUP205 DST LRBA DYNC1H1	1.73e-05	235	126	9	int:EPHA1
Interaction	KRT78 interactions	KRT31 KRT33B NUMA1 PLEC KRT38 KRT37	1.77e-05	87	126	6	int:KRT78
Interaction	TXLNA interactions	CYP1A1 CENPF KRT31 CEP162 ARHGEF12 DST ADSL KRT38 CCDC136	1.78e-05	236	126	9	int:TXLNA
Interaction	KRT75 interactions	KRT2 KRT31 KRT33B NUMA1 AMOT KRT38 KRT37 MTUS2	1.85e-05	181	126	8	int:KRT75
Interaction	USP2 interactions	GRIPAP1 KRT31 KRT33B ACTN2 SPAG8 SF3B1 RABEP1 MTUS2 CCDC136	1.97e-05	239	126	9	int:USP2
Interaction	YWHAQ interactions	TET2 TPR DLG5 ACACA TTC28 CEP162 NUMA1 ACTN2 PFKFB3 LYST DST PIK3C2A RABEP1 MACF1 PLEC LRBA PLCH1 FGD6 G6PD DYNC1H1	1.99e-05	1118	126	20	int:YWHAQ
Interaction	MTNR1B interactions	USP34 DST SYNE2 VPS35 MACF1 RNF41 DYNC1H1	2.25e-05	135	126	7	int:MTNR1B
Interaction	NEFM interactions	DLG5 DSP KRT31 SYNE1 NUP205 PLEC KRT38 KRT37	2.62e-05	190	126	8	int:NEFM
Interaction	KRT72 interactions	KRT31 KRT33B NUMA1 KRT38 KRT37	3.37e-05	59	126	5	int:KRT72
Interaction	SCNM1 interactions	KRT31 YBEY KRT33B SF3B1 RBAK KRT38 MTUS2 CCDC136	3.39e-05	197	126	8	int:SCNM1
Interaction	FBXO22 interactions	WAPL ACACA CENPF NUMA1 CHD2 MAGT1 OPA1 GTF3C4 TRANK1 CROCC2 VPS35 LRBA G6PD	3.43e-05	540	126	13	int:FBXO22
Interaction	AXDND1 interactions	SYNE1 SRP72 PLEC	3.80e-05	11	126	3	int:AXDND1
Interaction	CFAP53 interactions	GRIPAP1 KRT31 CCNC RABEP1	4.02e-05	31	126	4	int:CFAP53
Interaction	DTNB interactions	KRT31 KRT33B DMD KRT38 MTUS2 CCDC136	4.13e-05	101	126	6	int:DTNB
Interaction	MCM2 interactions	TPR CYP1A1 KRT2 ACACA DSP SYNE1 NUMA1 SRP72 OPA1 GTF3C4 CCNC SF3B1 DST ADSL MACF1 PLEC DMD G6PD DYNC1H1	4.19e-05	1081	126	19	int:MCM2
Interaction	KRT4 interactions	KRT31 KRT33B NUMA1 KRT38 KRT37	4.29e-05	62	126	5	int:KRT4
Interaction	TERF2 interactions	CENPF SYNE1 NUMA1 REV3L SF3B1 DST SYNE2 RASGEF1C MACF1 DMD	5.59e-05	340	126	10	int:TERF2
Interaction	LMO4 interactions	KRT31 RBBP8 KRT33B AMOT RBAK KRT38 MTUS2	6.42e-05	159	126	7	int:LMO4
Interaction	YWHAZ interactions	TET2 DLG5 TTC28 CEP162 PFKFB3 LYST LIMK1 SF3B1 DST ADSL PIK3C2A RABEP1 SYNE2 MACF1 RNF41 PLEC PLCH1 FGD6 G6PD DYNC1H1 ARHGEF6	6.67e-05	1319	126	21	int:YWHAZ
Interaction	BIRC3 interactions	DNHD1 TPR WAPL KIF27 MYO1D CENPF DSP SYNE1 NUMA1 DUOX2 SRP72 PSMD4 NUP205 SF3B1 ADSL AMOT VPS35 TLN2 G6PD DYNC1H1 KIFC1	7.83e-05	1334	126	21	int:BIRC3
Interaction	KRT74 interactions	KRT31 KRT33B KRT38 KRT37	8.20e-05	37	126	4	int:KRT74
Interaction	CCP110 interactions	KRT2 CEP162 AMOT VPS35 RNF41 KRT38 MTUS2	8.42e-05	166	126	7	int:CCP110
Interaction	KXD1 interactions	CENPF NUMA1 RABEP1 VPS35 KRT38 KRT37 CCDC136	9.77e-05	170	126	7	int:KXD1
Interaction	CCDC187 interactions	GRIPAP1 KRT31 ACTN2 MTUS2 CCDC136	1.14e-04	76	126	5	int:CCDC187
Interaction	SSH3 interactions	YBEY NUMA1 NUP205 LIMK1 VPS35	1.14e-04	76	126	5	int:SSH3
Interaction	KRT6C interactions	KRT31 KRT33B PLEC KRT38 KRT37	1.14e-04	76	126	5	int:KRT6C
Interaction	MOS interactions	KRT31 KRT33B ACTN2 MTUS2 CCDC136	1.29e-04	78	126	5	int:MOS
Interaction	ARRB2 interactions	CENPF ARHGEF12 PFKFB3 LIMK1 SF3B1 PIK3C2A SYNE2 VPS35 NFKBIL1 DYNC1H1 ARHGEF6	1.33e-04	454	126	11	int:ARRB2
Interaction	PCNT interactions	ACACA CEP162 SYNE1 DST AMOT MACF1 PLEC KRT38	1.39e-04	241	126	8	int:PCNT
Interaction	PKN3 interactions	GRIPAP1 URI1 MYO1D KRT31 RABEP1 KRT38 MTUS2	1.44e-04	181	126	7	int:PKN3
Interaction	KRT71 interactions	KRT31 KRT33B KRT38 KRT37	1.49e-04	43	126	4	int:KRT71
Interaction	ZNF20 interactions	KRT31 KRT38 MTUS2 CCDC136	1.63e-04	44	126	4	int:ZNF20
Interaction	ACE2 interactions	TET2 TPR KRT2 GRIPAP1 ACACA MYO1D DSP NUMA1 SRP72 NUP205 SF3B1 AMOT RABEP1 VPS35 PLEC G6PD DYNC1H1 CAVIN2	1.79e-04	1106	126	18	int:ACE2
Interaction	ZFYVE21 interactions	KRT31 NUMA1 ARL6IP1 KRT38 MTUS2	1.83e-04	84	126	5	int:ZFYVE21
Interaction	KRT76 interactions	KRT31 KRT33B KRT38 KRT37 MTUS2	1.83e-04	84	126	5	int:KRT76
Interaction	FLOT1 interactions	DLG5 MYO1D ARHGEF12 ETV6 PSMD4 KCNB2 DST MACF1 PLEC PLCH1 ILVBL	1.98e-04	475	126	11	int:FLOT1
Interaction	FOXB1 interactions	WAPL KRT31 GTF3C4 NUP205 SF3B1 DYNC1H1	2.06e-04	135	126	6	int:FOXB1
Interaction	KRT5 interactions	KRT2 DSP KRT31 KRT33B DST KRT38 KRT37	2.14e-04	193	126	7	int:KRT5
Interaction	PSMA1 interactions	ACACA MYO1D KRT31 PSMD4 ACTN2 MID1 PLCH1 KRT38 KRT37 MTUS2 CCDC136	2.16e-04	480	126	11	int:PSMA1
Interaction	SMC3 interactions	WAPL NUMA1 ARHGEF12 GTF3C4 MSANTD3 SF3B1 PLEC PLCH1 DYNC1H1 MXD1	2.48e-04	408	126	10	int:SMC3
Interaction	HAPLN2 interactions	KRT31 KRT33B KRT37 MTUS2	2.48e-04	49	126	4	int:HAPLN2
Interaction	PPP1R18 interactions	GRIPAP1 URI1 KRT31 KRT33B MTUS2 CCDC136	2.61e-04	141	126	6	int:PPP1R18
Interaction	PIBF1 interactions	GRIPAP1 CEP162 AMOT KRT38 KRT37 MTUS2 CCDC136	2.66e-04	200	126	7	int:PIBF1
Interaction	BRCA1 interactions	DNHD1 TPR WAPL ACACA TTC28 CENPF DSP RBBP8 NUMA1 ETV6 SRP72 PSMD4 GTF3C4 SF3B1 DST VPS35 PLEC DYNC1H1 KIFC1	2.76e-04	1249	126	19	int:BRCA1
Interaction	HOOK3 interactions	DLG5 ACACA KRT31 NUBP1 PLEC KRT37 DYNC1H1	2.83e-04	202	126	7	int:HOOK3
Interaction	KRT27 interactions	KRT2 CCNC AMOT RABEP1 CFAP58 TRAF3IP3 ARHGEF6	2.83e-04	202	126	7	int:KRT27
Interaction	SEPTIN10 interactions	DLG5 SEPTIN5 CENPF ADSL SEPTIN14 KRT38	2.92e-04	144	126	6	int:SEPTIN10
Interaction	TCEANC interactions	KRT31 CCNC MID1 RNF41 MTUS2 CCDC136	3.03e-04	145	126	6	int:TCEANC
Interaction	ZNF785 interactions	USP34 GTF3C4 RBAK MTUS2 CCDC136	3.26e-04	95	126	5	int:ZNF785
Interaction	CEP57L1 interactions	GRIPAP1 KRT31 KRT38 MTUS2 CCDC136	3.26e-04	95	126	5	int:CEP57L1
Interaction	DSCR9 interactions	SYNE1 DST SGSM2 MACF1 MTUS2 DYNC1H1	3.26e-04	147	126	6	int:DSCR9
Interaction	KRT81 interactions	KRT31 KRT33B KRT38 KRT37	3.37e-04	53	126	4	int:KRT81
Interaction	RTP5 interactions	KRT31 KRT33B ACTN2 MTUS2	3.37e-04	53	126	4	int:RTP5
Interaction	C21orf58 interactions	KRT37 MTUS2 CCDC136	3.37e-04	22	126	3	int:C21orf58
Interaction	TERF1 interactions	DLG5 CENPF NUMA1 PSMD4 DST SYNE2 RASGEF1C CFAP58 DMD	3.38e-04	347	126	9	int:TERF1
Interaction	CYLD interactions	KRT2 DLG5 DSP ARHGEF12 ETV6 PSMD4 PFKFB3 SF3B1 AMOT VPS35 RNF41 PLEC ACAP2 G6PD DYNC1H1	3.45e-04	868	126	15	int:CYLD
Interaction	RNF43 interactions	DLG5 URI1 TTC28 PSMD4 MAGT1 KCNB2 AMOT PURA MACF1 LRBA	3.55e-04	427	126	10	int:RNF43
Interaction	FAM90A1 interactions	GRIPAP1 KRT31 PSMD4 CCNC RABEP1 KRT38 MTUS2	3.58e-04	210	126	7	int:FAM90A1
Interaction	NTAQ1 interactions	KRT31 RBBP8 ETV6 ACTN2 ANKRD36B ARL6IP1 AMOT SEPTIN14 LRIF1 MTUS2	3.83e-04	431	126	10	int:NTAQ1
Interaction	HSF4 interactions	KRT31 RABEP1 KRT38 KRT37	4.16e-04	56	126	4	int:HSF4
Interaction	TCP10L3 interactions	GRIPAP1 NUMA1 RABEP1	4.39e-04	24	126	3	int:TCP10L3
Interaction	FAAP100 interactions	KRT31 KRT33B SEPTIN14 KRT38 KRT37	4.53e-04	102	126	5	int:FAAP100
Interaction	KRT79 interactions	KRT31 KRT33B KRT38 KRT37	5.08e-04	59	126	4	int:KRT79
Interaction	OBSL1 interactions	TPR CENPF DSP KRT33B SYNE1 NUMA1 NUP205 SF3B1 DST CROCC2 SYNE2 VPS35 MACF1 PLEC DYNC1H1	5.15e-04	902	126	15	int:OBSL1
Interaction	MED4 interactions	DLG5 TTC28 CEP162 CCNC DST ADSL AMOT LRBA ACAP2 ARHGEF6	5.36e-04	450	126	10	int:MED4
Interaction	RNF13 interactions	VIPR1 PGK2 NR2F2 AP1G2	5.42e-04	60	126	4	int:RNF13
Interaction	ACTA1 interactions	TET2 ETV6 ACTN2 CORO2B DST AMOT MACF1 PLEC DMD	5.48e-04	371	126	9	int:ACTA1
Interaction	SNCA interactions	TPR SEPTIN5 CENPF DSP KRT31 NUMA1 DST SYNE2 TTI1 MACF1 TLN2 ILVBL DYNC1H1	5.51e-04	716	126	13	int:SNCA
Interaction	KRT85 interactions	KRT31 KRT33B KRT38 KRT37	5.77e-04	61	126	4	int:KRT85
Interaction	NDEL1 interactions	GRIPAP1 CENPF SYNE1 TRAF3IP3 MTUS2 DYNC1H1	5.84e-04	164	126	6	int:NDEL1
Interaction	YWHAB interactions	TET2 DLG5 URI1 TTC28 CEP162 PFKFB3 LYST DST PIK3C2A AMOT RABEP1 MACF1 PLCH1 FGD6 G6PD DYNC1H1	5.89e-04	1014	126	16	int:YWHAB
Interaction	CCHCR1 interactions	GRIPAP1 KRT31 CCNC RABEP1 KRT38 MTUS2 CCDC136	6.00e-04	229	126	7	int:CCHCR1
Interaction	CEP97 interactions	KRT2 CEP162 AMOT VPS35 RNF41 KRT38	6.03e-04	165	126	6	int:CEP97
Interaction	MAPRE3 interactions	DLG5 TTC28 CENPF CEP162 SF3B1 DST MACF1	6.16e-04	230	126	7	int:MAPRE3
Interaction	CCDC120 interactions	KRT31 SPAG8 RABEP1 KRT38 MTUS2 CCDC136	6.84e-04	169	126	6	int:CCDC120
Interaction	SNAPIN interactions	ACTN2 DST RABEP1 MACF1 PLEC DYNC1H1	6.84e-04	169	126	6	int:SNAPIN
Interaction	PIN1 interactions	CYP1A1 KRT31 RBBP8 ETV6 AMOT KRT38 LRIF1 KRT37 MTUS2	6.87e-04	383	126	9	int:PIN1
Interaction	PTEN interactions	TPR ACACA MYO1D DSP CEP162 PSMD4 KCNB2 ITGB7 SF3B1 AMOT PURA OSBP2 PLEC ACAP2 MXD1	6.98e-04	929	126	15	int:PTEN
Interaction	NUP205 interactions	TPR VIPR1 ACACA NUMA1 NUP205 TMEM9 ILVBL	6.99e-04	235	126	7	int:NUP205
Interaction	DSCAM interactions	SYNE1 LIMK1 DST MACF1 PLEC DYNC1H1	7.27e-04	171	126	6	int:DSCAM
Interaction	ZNF648 interactions	KRT31 RBAK MTUS2 CCDC136	7.35e-04	65	126	4	int:ZNF648
Cytoband	17q12-q21	KRT31 KRT33A KRT38 KRT37	2.08e-06	32	130	4	17q12-q21
GeneFamily	EF-hand domain containing\|Plakins	DSP DST MACF1 PLEC	2.99e-08	8	84	4	939
GeneFamily	Keratins, type I	KRT31 KRT33A KRT33B KRT38 KRT37	1.73e-07	28	84	5	608
GeneFamily	Spectrin repeat containing nuclear envelope family	SYNE1 SYNE2	1.27e-04	4	84	2	1252
GeneFamily	6-phosphofructo-2-kinases/fructose-2,6-biphosphatases	PFKFB1 PFKFB3	1.27e-04	4	84	2	1077
GeneFamily	Ankyrin repeat domain containing	ANKS1B ANKRD36C ANKRD36B TRANK1 ANKAR ANKRD36 ACAP2	1.33e-04	242	84	7	403
GeneFamily	WD repeat domain containing\|BEACH domain containing	LYST LRBA	7.52e-04	9	84	2	1230
GeneFamily	Septins	SEPTIN5 SEPTIN14	1.61e-03	13	84	2	732
GeneFamily	X-linked mental retardation\|Angiotensin receptors	MAGT1 DMD ARHGEF6	1.92e-03	53	84	3	103
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGEF12 FGD6 ARHGEF6	3.59e-03	66	84	3	722
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	USP34 URI1 WAPL TTC28 CENPF REV3L OPA1 NR2F2 DST PIK3C2A SYNE2 MID1 MACF1 DMD ZBTB11 ACAP2	2.94e-06	856	124	16	M4500
Coexpression	GSE7764_IL15_TREATED_VS_CTRL_NK_CELL_24H_DN	TET2 PLVAP SYNE1 LYST PTH1R RBAK ACAP2 MXD1	5.16e-06	200	124	8	M5724
Coexpression	TANAKA_METHYLATED_IN_ESOPHAGEAL_CARCINOMA	KRT2 KRT31 KRT33A KRT33B KRT38 KRT37	9.22e-06	102	124	6	M14455
Coexpression	MITSIADES_RESPONSE_TO_APLIDIN_DN	TPR URI1 CENPF DSP NUP205 SF3B1 MACF1 PLEC	2.60e-05	250	124	8	M11318
Coexpression	MURARO_PANCREAS_BETA_CELL	USP34 MYO1D DSP RBBP8 MAFA LYST DST PIK3C2A PTPRN RABEP1 PURA SYNE2 VPS35 MTUS2 DYNC1H1	4.19e-05	946	124	15	M39169
Coexpression	HALLMARK_MITOTIC_SPINDLE	CENPF NUMA1 ARHGEF12 DST MID1 FGD6 DYNC1H1	4.65e-05	199	124	7	M5893
Coexpression	GSE28726_ACT_CD4_TCELL_VS_ACT_VA24NEG_NKTCELL_DN	USP34 DLG5 SYNE1 HERC2P3 TRANK1 SGSM2 SYNE2	4.80e-05	200	124	7	M8306
Coexpression	LAKE_ADULT_KIDNEY_C2_PODOCYTES	TET2 MYO1D ARHGEF12 PTH1R DST MACF1 ANKRD36	6.94e-05	212	124	7	M39221
Coexpression	GABRIELY_MIR21_TARGETS	USP34 ARHGEF12 REV3L PIK3C2A PURA SYNE2 DMD ACAP2	7.23e-05	289	124	8	M2196
Coexpression	BROWNE_HCMV_INFECTION_14HR_DN	SYNE1 NUMA1 PSMD4 REV3L DST AMOT TRAF3IP3 PLEC	7.41e-05	290	124	8	M13251
Coexpression	CAMPS_COLON_CANCER_COPY_NUMBER_UP	KRT31 KRT33A KRT33B KRT38 KRT37	8.14e-05	93	124	5	M18750
Coexpression	HOEBEKE_LYMPHOID_STEM_CELL_UP	TPR USP34 SF3B1 MACF1 TRAF3IP3	9.95e-05	97	124	5	M14698
Coexpression	WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_UP	TET2 MANBA ACRBP CHD2 PSTPIP2 HERC2P3 ITGB7 AP1G2 TRAF3IP3	1.07e-04	392	124	9	M2131
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#4_top-relative-expression-ranked_1000	ACACA DSP RBBP8 TRANK1 CCDC171	3.66e-06	41	122	5	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k4_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	CENPF CEP162 CHD2 REV3L CORO2B RABEP1 SYNE2 TTI1 LRBA FGD6	1.27e-05	311	122	10	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#3	TTC28 CENPF CHD2 OPA1 TTI1 MACF1 LRBA FGD6 MXD1	4.75e-05	291	122	9	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000_K3
ToppCell	systemic_lupus_erythematosus-flare\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	TPR URI1 SYNE1 CHD2 SF3B1 ARL6IP1 SYNE2 MACF1 ANKRD36 TRAF3IP3	2.29e-10	198	124	10	4c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	USP34 CHD2 ANKRD36C SYNE2 MACF1 ANKRD36 LRBA ZBTB11 DYNC1H1	3.01e-09	188	124	9	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	USP34 CHD2 ACTN2 ANKRD36C ANKRD36B SYNE2 MACF1 LRBA	1.83e-08	162	124	8	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	USP34 CHD2 ANKRD36C ANKRD36B SYNE2 MACF1 ANKRD36 LRBA	4.35e-08	181	124	8	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	COVID_non-vent-Lymphocytic\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	SYNE1 CHD2 ANKRD36C TRANK1 SYNE2 MACF1 ANKRD36 TRAF3IP3	8.36e-08	197	124	8	c672915f8c8c1e948d251f6eaf9f84a5600c1193
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	USP34 SYNE1 CHD2 ANKRD36C SYNE2 MACF1 ANKRD36 LRBA	9.03e-08	199	124	8	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TET2 TPR USP34 CHD2 SF3B1 SYNE2 MACF1 DYNC1H1	9.39e-08	200	124	8	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	SYNE1 CHD2 ANKRD36C SYNE2 MACF1 ANKRD36 LRBA	1.05e-07	135	124	7	ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	CHD2 ANKRD36C ANKRD36B SYNE2 MACF1 ANKRD36 LRBA	2.26e-07	151	124	7	999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR WAPL SYNE1 LYST ARL6IP1 SYNE2 CAVIN2	6.87e-07	178	124	7	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEPTIN5 CENPF SYNE1 MSANTD3 SYNE2 G6PD KIFC1	6.87e-07	178	124	7	15a99080e9f669572ab6d82934f324e6714846c1
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEPTIN5 CENPF SYNE1 MSANTD3 SYNE2 G6PD KIFC1	6.87e-07	178	124	7	200308e109abb7e6f8816a6f8cce6d56862d4098
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DLG5 DSP CHD2 ANKRD36C ANKRD36B SGSM2 MACF1	7.14e-07	179	124	7	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANKRD36C ESCO1 THADA SYNE2 MACF1 LRBA CCDC136	1.06e-06	190	124	7	91ba66d4b56c59523485b17738e93f14bb00afa4
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNE1 ITGB7 ANKRD36B SYNE2 MACF1 ANKRD36 TRAF3IP3	1.06e-06	190	124	7	d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR USP34 WAPL DSP ESCO1 ARL6IP1 SYNE2	1.10e-06	191	124	7	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR USP34 WAPL DSP ESCO1 ARL6IP1 SYNE2	1.10e-06	191	124	7	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR USP34 WAPL DSP ESCO1 ARL6IP1 SYNE2	1.10e-06	191	124	7	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	USP34 SYNE1 ANKRD36C SYNE2 MACF1 ANKRD36 LRBA	1.35e-06	197	124	7	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	USP34 ACACA MYO1D TTC28 ETV6 LRBA DMD	1.45e-06	199	124	7	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	TET2 TPR REV3L DST PURA SYNE2 ANKRD36	1.45e-06	199	124	7	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	USP34 ARHGEF12 DST PIK3C2A SYNE2 MACF1 FGD6	1.50e-06	200	124	7	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	COVID-19_Moderate-multiplets\|World / disease group, cell group and cell class	SYNE1 ANKRD36C ANKRD36B SYNE2 MACF1 ANKRD36	5.03e-06	156	124	6	afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IQANK1 DNAH3 CORO2B CROCC2 SGSM2 MID1	8.51e-06	171	124	6	1854a777d9eb9d3fc3ed3632332a6f89ce8131da
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	SYNE1 CHD2 ANKRD36C SYNE2 MACF1 ANKRD36	8.51e-06	171	124	6	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR LYST ESCO1 NR2F2 MACF1 DMD	1.00e-05	176	124	6	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEPTIN5 SYNE1 PSTPIP2 LYST G6PD MXD1	1.04e-05	177	124	6	065bebd22031f143e90a407f952b444a3f8818c7
ToppCell	droplet-Limb_Muscle-nan-21m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	REXO1 PTH1R NR2F2 THADA RASGEF1C TTI1	1.04e-05	177	124	6	291231b1520c135e92739e201495fe1935efa927
ToppCell	facs-Marrow-Granulocytes-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEPTIN5 SYNE1 PSTPIP2 LYST G6PD MXD1	1.04e-05	177	124	6	eb304f20aab075bd17aa3aef819386c0e1a235bd
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	SYNE1 NUMA1 CHD2 DST PURA DYNC1H1	1.04e-05	177	124	6	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN3_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACRBP GTF3C4 MSANTD3 ZBTB11 G6PD MXD1	1.18e-05	181	124	6	e2d03115a87f45a7ddd3ade6b9ac3843639bd41a
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACRBP GTF3C4 MSANTD3 ZBTB11 G6PD MXD1	1.18e-05	181	124	6	d8d11ef83c4b8b6a6f5c8728e03059e45a8ad264
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	DSP CHD2 TRANK1 DST SYNE2 FGD6	1.25e-05	183	124	6	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	Brain_organoid-organoid_Kanton_Nature\|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.	WAPL ANKRD36C NR2F2 ANKRD36B SYNE2 MID1	1.33e-05	185	124	6	857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	TPR USP34 WAPL ARHGEF12 TRANK1 PIK3C2A	1.37e-05	186	124	6	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	droplet-Bladder-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR WAPL SF3B1 ARL6IP1 PURA SYNE2	1.41e-05	187	124	6	663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	MYO1D ANKS1B ETV6 MID1 MACF1 DMD	1.46e-05	188	124	6	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	MYO1D ANKS1B ETV6 MID1 MACF1 DMD	1.50e-05	189	124	6	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	droplet-Lung-LUNG-1m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1A1 PLVAP TTC28 NR2F2 DST CAVIN2	1.59e-05	191	124	6	9fc674a58f20b47255e4457d5195c8cff17b0414
ToppCell	droplet-Lung-LUNG-1m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1A1 PLVAP TTC28 NR2F2 DST CAVIN2	1.59e-05	191	124	6	c379a499dabf3c9ed80f47adbb2d949821c5b053
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	CHD2 ANKRD36C ANKRD36B SYNE2 MACF1 ANKRD36	1.64e-05	192	124	6	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	facs-Aorta-Heart-3m\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MANBA SYNE1 SF3B1 VPS35 MACF1 FGD6	1.64e-05	192	124	6	1ccc47792edf9ee23501c8e2165d11271636b66a
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 ANKRD36C SYNE2 MACF1 ANKRD36 LRBA	1.69e-05	193	124	6	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	droplet-Limb_Muscle-MUSCLE\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR USP34 WAPL PFKFB3 MACF1 CAVIN2	1.74e-05	194	124	6	e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TTC28 ANKS1B PTH1R NR2F2 DST MACF1	1.74e-05	194	124	6	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	DNAH3 MYO1D SYNE1 ARHGEF12 SYNE2 PLCH1	1.79e-05	195	124	6	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	IPF-Endothelial-Lymphatic\|Endothelial / Disease state, Lineage and Cell class	SEPTIN5 DSP CEP162 NR2F2 OSBP2 CAVIN2	1.79e-05	195	124	6	de88e9d22044b4b3e29676ad02b3e9299cc920ad
ToppCell	COVID_non-vent-Lymphocytic-T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	CHD2 ANKRD36C SYNE2 MACF1 ANKRD36 TRAF3IP3	1.79e-05	195	124	6	4bdedd924564a260841a9153604026b57487c83d
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TTC28 ANKS1B PTH1R NR2F2 DST MACF1	1.79e-05	195	124	6	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	DNAH3 MYO1D SYNE1 ARHGEF12 SYNE2 PLCH1	1.79e-05	195	124	6	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC28 REV3L DST PTPRN MACF1 DYNC1H1	1.79e-05	195	124	6	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC28 REV3L DST PTPRN MACF1 DYNC1H1	1.79e-05	195	124	6	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	ACACA MYO1D TTC28 ANKS1B LRBA DMD	1.85e-05	196	124	6	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SYNE1 ANKS1B KCNB2 ANKRD36B ANKRD36 MTUS2	1.85e-05	196	124	6	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	DNAH3 SYNE1 ARHGEF12 SYNE2 MACF1 PLCH1	1.85e-05	196	124	6	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	Control-Endothelial-Lymphatic\|Endothelial / Disease state, Lineage and Cell class	MYO1D DSP NR2F2 DST OSBP2 CAVIN2	1.85e-05	196	124	6	e0cf617b0f5d9c3c19574f587a3d0ccbf93d8ca4
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	DNAH3 SYNE1 ARHGEF12 SYNE2 MACF1 PLCH1	1.85e-05	196	124	6	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	mild-low-quality_cells\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	DLG5 SYNE1 ANKRD36C SYNE2 ANKRD36 LRBA	1.90e-05	197	124	6	e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 KIF27 SYNE1 CROCC2 SYNE2 DMD	1.90e-05	197	124	6	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 MYO1D DSP DUOX2 ANKRD36C PLEC	1.90e-05	197	124	6	5c4cee914baf7cb43e9cb99cc9e3ae823856dc15
ToppCell	Control-Control-Lymphocyte-T/NK-NK_activated\|Control / Disease, condition lineage and cell class	DLG5 SYNE1 TRANK1 SYNE2 MACF1 MDGA1	1.95e-05	198	124	6	76d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCell	Control_saline\|World / Treatment groups by lineage, cell group, cell type	CYP1A1 DSP DST MACF1 PLEC CAVIN2	2.01e-05	199	124	6	11c9c1779caceb725ecccf3f23b7d4e6dbd1af64
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SYNE1 ACTN2 REV3L NR2F2 DST MACF1	2.01e-05	199	124	6	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	healthy_donor-Lymphocytic\|healthy_donor / Disease condition, Lineage, Cell class and subclass	SYNE1 ITGB7 SYNE2 MACF1 ANKRD36 TRAF3IP3	2.01e-05	199	124	6	2841e16d54acd344ba454f024e285c28abc37319
ToppCell	COVID-19_Moderate\|World / disease group, cell group and cell class	DSP SYNE1 ANKRD36C ANKRD36B TRANK1 SYNE2	2.01e-05	199	124	6	952fac67588ad5676f5939e3c7f8bac803c27064
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-dn_T\|COVID-19_Mild / Disease, condition lineage and cell class	LYST TRANK1 SYNE2 MACF1 LRBA ARHGEF6	2.01e-05	199	124	6	f307d4887b28cf60a591439e278fd668409cb104
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ARHGEF12 DST SYNE2 MACF1 DYNC1H1 CAVIN2	2.07e-05	200	124	6	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DLG5 MYO1D DSP ARHGEF12 DST SYNE2	2.07e-05	200	124	6	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ARHGEF12 DST SYNE2 MACF1 DYNC1H1 CAVIN2	2.07e-05	200	124	6	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	SYNE1 ANKS1B KCNB2 ANKRD36B ANKRD36 MTUS2	2.07e-05	200	124	6	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	VIPR1 ARHGEF12 DST SYNE2 MACF1 DYNC1H1	2.07e-05	200	124	6	79e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PLVAP ARHGEF12 DST SYNE2 MACF1 CAVIN2	2.07e-05	200	124	6	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated\|COVID-19_Mild / Disease, condition lineage and cell class	DLG5 SYNE1 ARHGEF12 TRANK1 SYNE2 MACF1	2.07e-05	200	124	6	2281debd86e5d92e8fe0397aec9ef670800f7471
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	TTC28 ACTN2 REV3L DST LPA MACF1	2.07e-05	200	124	6	a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell	NS-control\|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DLG5 MYO1D DSP ARHGEF12 DST SYNE2	2.07e-05	200	124	6	ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	SYNE1 ACTN2 NR2F2 DST LPA MACF1	2.07e-05	200	124	6	bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	SYNE1 ANKRD36C SYNE2 MACF1 ANKRD36	2.26e-05	121	124	5	19333a660800b583fa27b495c1f7828e6636a257
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TET2 MAFA ETV6 PFKFB3 MXD1	5.02e-05	143	124	5	7adc34d8ad11e57950a5a258ae9bf8f52259385a
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	CHD2 ANKRD36C MACF1 ANKRD36 DYNC1H1	5.73e-05	147	124	5	94998bc40f5c08295cfe3bdcbe43f13b1e564b3d
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 DUOX2 SPAG8 CROCC2 CFAP58	7.36e-05	155	124	5	5f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DNAH3 DUOX2 SPAG8 CROCC2 CFAP58	7.36e-05	155	124	5	0944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCell	10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	ANKRD36B SYNE2 ANKRD36 LRBA PLCH1	7.59e-05	156	124	5	10d191e29b16cae8238e8df6c0ff38882253f34e
ToppCell	PBMC-Mild-Hematopoietic-Platelet-Platelet-plt_0\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SEPTIN5 ACRBP OSBP2 PLCH1 CAVIN2	9.89e-05	165	124	5	6799a6580c667738995cceb31cbf1c7fbdc4ff84
ToppCell	PBMC-Mild-Hematopoietic-Platelet-Platelet-plt_0\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SEPTIN5 ACRBP OSBP2 PLCH1 CAVIN2	9.89e-05	165	124	5	8329d780f244bc31344443b29e5a00529a016662
ToppCell	droplet-Spleen-nan-24m-Myeloid-granulocyte\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEPTIN5 SYNE1 MSANTD3 G6PD MXD1	9.89e-05	165	124	5	3cdb921f5b9facf04f81995d5641ac14ef3dbb6f
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPF SYNE1 TLN2 ANKRD36 PLEC	1.05e-04	167	124	5	1bd27ffe381d26731b6d4cc5f29b27f1bac4473b
ToppCell	droplet-Spleen-nan-21m-Myeloid-granulocyte\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEPTIN5 SYNE1 MSANTD3 G6PD MXD1	1.05e-04	167	124	5	cfcd72292c733cdb18c92fdb61b68f6806d22c8c
ToppCell	droplet-Spleen-SPLEEN-30m-Myeloid-granulocyte\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEPTIN5 SYNE1 MSANTD3 G6PD MXD1	1.08e-04	168	124	5	c0ff30e2c47005514131a0866cf10a1c228128fc
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPF SYNE1 TLN2 ANKRD36 PLEC	1.08e-04	168	124	5	faaba5ac01c2ebe380f56559374a121979a85a13
ToppCell	facs-Marrow-Granulocytes\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEPTIN5 SYNE1 LYST G6PD MXD1	1.17e-04	171	124	5	1701dedf0c18751db6c9fee3d93fff150ed0e17f
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination__)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	URI1 BMF NUMA1 PTPRN ILVBL	1.17e-04	171	124	5	d1e87478d8c0329e662849823f5c7604f20e1b1a
ToppCell	facs-Marrow-T_cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEPTIN5 SYNE1 SYNE2 G6PD KIFC1	1.17e-04	171	124	5	95e87987a2332fa646849fb0de785f1e0b8a07dd
ToppCell	facs-Marrow-T_cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEPTIN5 SYNE1 SYNE2 G6PD KIFC1	1.17e-04	171	124	5	36657e277aad75c4f157c1726c48e09b5836cf37
ToppCell	356C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	PLVAP BMF ARHGEF12 PFKFB3 MID1	1.17e-04	171	124	5	bdd30100b74e012eec3090799c22635aa57fa91d
ToppCell	droplet-Marrow-BM_(NON-STC)\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WAPL CENPF SYNE1 TLN2 ANKRD36	1.20e-04	172	124	5	6004327045f03d832fdabe6cb2f8b1b1db57789a
ToppCell	droplet-Marrow-BM_(NON-STC)-30m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WAPL CENPF SYNE1 TLN2 ANKRD36	1.20e-04	172	124	5	31c5710fd7ebb221e703545595f5ec0ee3a32bcf
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ANKS1B ACTN2 TLN2 DMD MTUS2	1.23e-04	173	124	5	cb6389536195443633adb06e5f1b7483530773d1
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRANK1 PIK3C2A RASGEF1C LRIF1 ILVBL	1.30e-04	175	124	5	bb898796662b97f7459b7dda7cecf6a9bde8b055
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CEP162 CORO2B AMOT CROCC2 C2orf42	1.34e-04	176	124	5	87de432c680b80555342afac864599bbc002c040
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	WAPL SYNE1 TRANK1 SYNE2 MACF1	1.37e-04	177	124	5	d3e6c768b88b7906f3c7fdd00ba20842212c14b1
Computational	Genes upregulated in subsets of cells of a given type within various tumors	SYNE1 ARHGEF12 ANKRD36C DST MACF1 DYNC1H1	2.82e-06	50	87	6	GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_4
Computational	Intermediate filaments and MT.	KRT2 SEPTIN5 CENPF DSP NUMA1 MID1	1.73e-05	68	87	6	MODULE_438
Computational	Genes upregulated in subsets of cells of a given type within various tumors	SYNE1 CHD2 SYNE2 MACF1 DYNC1H1	4.46e-05	49	87	5	GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
Drug	plakin	DSP SYNE1 DST SYNE2 MACF1 PLEC DMD DYNC1H1	1.67e-08	82	125	8	CID000018752
Drug	AC1L1I0J	KRT31 KRT33A KRT33B KRT38 KRT37	5.03e-08	19	125	5	CID000004371
Drug	AC1L9LMC	ACACA SYNE1 SPAG8 LYST DST SYNE2 PLEC	3.73e-07	83	125	7	CID000448113
Drug	AC1L1GT5	KIF27 MANBA DSP KRT31 ANKS1B KRT38 DYNC1H1	9.40e-07	95	125	7	CID000003829
Drug	AC1L9MJT	TPR KRT2 KRT31 KRT33A KRT33B DST PLEC KRT38 KRT37	1.18e-06	192	125	9	CID000448959
Drug	Vistar	KRT31 KRT33A KRT33B KRT38 KRT37	1.51e-06	36	125	5	CID000040896
Drug	Mephentermine hemisulfate [1212-72-2]; Down 200; 9.4uM; PC3; HT_HG-U133A	USP34 TTC28 CENPF SYNE1 SPAG8 LYST THADA RABEP1 SGSM2	1.52e-06	198	125	9	7384_DN
Drug	tiapamil	SYNE1 PIK3C2A DMD	3.19e-06	6	125	3	CID000042106
Drug	1-2q	KRT2 DSP KRT31 KRT33A KRT33B ETV6 ITGB7 PLEC KRT38 KRT37	4.56e-06	289	125	10	CID000011820
Drug	9-(5',5'-difluoro-5'-phosphonopentyl)guanine	KRT31 KRT33A KRT33B KRT38 KRT37	5.27e-06	46	125	5	CID000448999
Drug	homocysteine thiolactone	KRT2 KRT31 KRT33A KRT33B LPA KRT38 KRT37	8.07e-06	131	125	7	CID000107712
Drug	NSC34533	KRT31 KRT33A KRT33B KRT38 KRT37	1.17e-05	54	125	5	CID000003512
Drug	Stachydrine hydrochloride; Down 200; 22.2uM; PC3; HT_HG-U133A	TTC28 CENPF CEP162 SYNE1 ARHGEF12 RABEP1 TLN2 PLCH1	1.30e-05	196	125	8	4469_DN
Drug	Harpagoside [19210-12-9]; Down 200; 8uM; MCF7; HT_HG-U133A	DLG5 TTC28 CEP162 NUMA1 SPAG8 LIMK1 PLEC PLCH1	1.45e-05	199	125	8	7355_DN
Drug	ICI182,780; Up 200; 1uM; MCF7; HT_HG-U133A	CYP1A1 DNAH3 TTC28 CENPF NUMA1 PSMD4 LIMK1 ARHGEF6	1.51e-05	200	125	8	7534_UP
Drug	chain-in	LYST MID1	2.99e-05	2	125	2	CID006444356
Drug	PCN 67	CYP1A1 PLEC	2.99e-05	2	125	2	CID000107693
Drug	A-Cw	LYST PIK3C2A LRBA	3.43e-05	12	125	3	CID013891726
Drug	glucose-6-P	MANBA ACACA PFKFB1 PFKFB3 PGK2 RABEP1 VPS35 AP1G2 LRBA G6PD	3.51e-05	366	125	10	CID000000208
Drug	DOPAC	ACACA KRT31 KRT33A KRT33B KRT38 KRT37	3.61e-05	112	125	6	CID000000547
Drug	adenosine 3',5'-cyclic phosphate	KRT2 VIPR1 ACACA KRT31 KRT33A KRT33B PFKFB1 PFKFB3 PTH1R ADSL LRBA DMD PLCH1 KRT38 KRT37 ILVBL	3.78e-05	907	125	16	CID000000274
Drug	AC1Q6RZ4	ACACA PFKFB1 PFKFB3 PGK2 LRBA G6PD	6.11e-05	123	125	6	CID000000719
Drug	teleocidin B	KRT2 KRT31 KRT33A KRT33B KRT38 KRT37	6.11e-05	123	125	6	CID000072425
Drug	Thr-Ala	PSMD4 PFKFB1 PFKFB3	7.00e-05	15	125	3	CID006427021
Drug	sulfur mustard	KRT2 KRT31 KRT33A KRT33B KRT38 KRT37	8.31e-05	130	125	6	CID000010461
Drug	propanedinitrile	MANBA SYNE1 PLEC	8.59e-05	16	125	3	CID000008010
Drug	AC1L40NT	SYNE1 PIK3C2A	8.94e-05	3	125	2	CID000099109
Drug	triasulfuron	KRT31 ILVBL	8.94e-05	3	125	2	CID000073282
Drug	2-hexadecyne	SYNE1 G6PD	8.94e-05	3	125	2	CID014009124
Drug	Norakin	KRT31 KRT37	8.94e-05	3	125	2	CID000161077
Drug	3-sulfanylhexyl acetate	PGK2 SYNE2	8.94e-05	3	125	2	CID000518810
Drug	PCN 66	CYP1A1 PLEC	8.94e-05	3	125	2	CID000107698
Disease	insomnia measurement	TET2 KCNB2 PTH1R PIK3C2A SGSM2 RASGEF1C PLCH1 MDGA1 MTUS2 RSKR	1.62e-05	443	122	10	EFO_0007876
Disease	Refractory anemia with ringed sideroblasts	TET2 SF3B1	1.70e-05	2	122	2	C1264195
Disease	Autosomal dominant Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	1.01e-04	4	122	2	cv:CN293514
Disease	latent autoimmune diabetes in adults	PFKFB3 THADA	1.01e-04	4	122	2	EFO_0009706
Disease	myeloproliferative neoplasm (is_implicated_in)	TET2 ETV6	1.01e-04	4	122	2	DOID:2226 (is_implicated_in)
Disease	Autosomal Recessive Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	1.68e-04	5	122	2	C1450051
Disease	Myelodysplastic syndrome	TET2 SF3B1	1.68e-04	5	122	2	cv:C3463824
Disease	Autosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)	SYNE1 SYNE2	1.68e-04	5	122	2	C0410190
Disease	MYELODYSPLASTIC SYNDROME	TET2 SF3B1	1.68e-04	5	122	2	614286
Disease	FEV/FEC ratio	TET2 USP34 DSP BMF ANKS1B ETV6 NR2F2 LIMK1 THADA DST CROCC2 SYNE2 RASGEF1C CCDC171 FGD6	1.70e-04	1228	122	15	EFO_0004713
Disease	Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	2.52e-04	6	122	2	cv:C0410189
Disease	Muscular Dystrophy, Emery-Dreifuss	SYNE1 SYNE2	2.52e-04	6	122	2	C0410189
Disease	Leukemia, Myelomonocytic, Chronic	TET2 ETV6	2.52e-04	6	122	2	C0023480
Disease	myelodysplastic syndrome (is_implicated_in)	TET2 ETV6 SF3B1	2.58e-04	30	122	3	DOID:0050908 (is_implicated_in)
Disease	Liver carcinoma	CYP1A1 VIPR1 PLVAP ACACA CENPF APOF PTH1R LPA KIFC1	2.67e-04	507	122	9	C2239176
Disease	epidermolysis bullosa simplex (is_implicated_in)	DST PLEC	3.51e-04	7	122	2	DOID:4644 (is_implicated_in)
Disease	X-Linked Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	3.51e-04	7	122	2	C0751337
Disease	lymphocyte count	TET2 KIF27 MANBA ACACA MYO1D TTC28 RBBP8 BMF PFKFB3 LYST ITGB7 PTH1R THADA RABEP1 PLEC ACAP2	3.57e-04	1464	122	16	EFO_0004587
Disease	Spastic Paraplegia	LYST ARL6IP1	5.99e-04	9	122	2	C0037772
Disease	migraine disorder	WAPL CENPF ANKRD36C REV3L THADA MACF1 DMD	7.30e-04	357	122	7	MONDO_0005277
Disease	arrhythmogenic right ventricular cardiomyopathy (is_implicated_in)	DSP ACTN2	7.47e-04	10	122	2	DOID:0050431 (is_implicated_in)
Disease	age at menarche	TET2 IQANK1 USP34 TTC28 CHD2 KCNB2 REXO1 DST OSBP2	8.32e-04	594	122	9	EFO_0004703
Disease	cancer (implicated_via_orthology)	ITGB7 PGK2 DST TTI1 MACF1 ACAP2	8.91e-04	268	122	6	DOID:162 (implicated_via_orthology)
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	SYNE1 SYNE2	1.09e-03	12	122	2	DOID:11726 (implicated_via_orthology)
Disease	age at menopause	ACACA TTC28 OPA1 NFKBIL1 LRIF1 DYNC1H1	1.64e-03	302	122	6	EFO_0004704
Disease	myelodysplastic syndrome (implicated_via_orthology)	TET2 SF3B1	1.72e-03	15	122	2	DOID:0050908 (implicated_via_orthology)
Disease	vital capacity	TET2 CYP1A1 USP34 DSP RBBP8 CEP162 SYNE1 BMF DST CROCC2 LRBA CCDC171 ARHGEF6	1.84e-03	1236	122	13	EFO_0004312
Disease	ankle brachial index	LPA DMD	1.96e-03	16	122	2	EFO_0003912
Disease	sphingomyelin 14:0 measurement	THADA SYNE2	2.21e-03	17	122	2	EFO_0010390
Disease	level of Sphingomyelin (d32:1) in blood serum	RABEP1 SYNE2	2.21e-03	17	122	2	OBA_2045173
Disease	testosterone measurement	TET2 KIF27 MANBA TTC28 BMF ANKS1B REXO1 THADA TMEM9 SYNE2 C2orf42 MACF1 ARHGEF6	2.41e-03	1275	122	13	EFO_0004908
Disease	late-onset myasthenia gravis	RBBP8 NFKBIL1	2.48e-03	18	122	2	EFO_1001490
Disease	susceptibility to vaginal yeast infection measurement	ANKS1B TLN2 MXD1	2.50e-03	65	122	3	EFO_0008412
Disease	Dermatitis, Allergic Contact	CYP1A1 NUMA1 MXD1	2.72e-03	67	122	3	C0162820
Disease	bipolar I disorder	SYNE1 RBPJL ANKS1B PLEC	2.84e-03	141	122	4	EFO_0009963
Disease	fatty acid measurement, linoleic acid measurement	KIF27 LPA CCDC171	2.84e-03	68	122	3	EFO_0005110, EFO_0006807
Disease	Contact Dermatitis	CYP1A1 KRT2 G6PD	3.21e-03	71	122	3	C0011616
Disease	Contact hypersensitivity	CYP1A1 KRT2 G6PD	3.21e-03	71	122	3	C0162351
Disease	nucleotide measurement	VIPR1 ANKS1B SYNE2	3.47e-03	73	122	3	EFO_0010513
Disease	migraine disorder, endometriosis	ETV6 RASGEF1C FGD6	3.47e-03	73	122	3	EFO_0001065, MONDO_0005277
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	LPA SYNE2 MACF1 LRBA	3.54e-03	150	122	4	EFO_0004611, EFO_0020947
Disease	Seckel syndrome	CENPF RBBP8	3.71e-03	22	122	2	C0265202
Disease	Parkinson's disease (is_implicated_in)	CYP1A1 SEPTIN14 VPS35	3.89e-03	76	122	3	DOID:14330 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
CVDNKNIQHINRIYR	YBEY	41	P58557
LKAATQGVVENQCQH	C2orf42	121	Q9NWW7
QGVVENQCQHIKLAV	C2orf42	126	Q9NWW7
NQCQHIKLAVNCQAE	C2orf42	131	Q9NWW7
ELERQENVLVICHQA	PFKFB1	381	P16118
VQLQAACEKREQLEH	AMOT	611	Q4VCS5
ANRICKVLAVNQENE	ACTN2	266	P35609
NTVERIVVHCNNNQD	ARHGEF6	521	Q15052
KIENDQQHQAAELEC	RBBP8	141	Q99708
CENEKEQAVHNVVQL	APOF	171	Q13790
KLEQCHSEASLQRQQ	ACRBP	381	Q8NEB7
LAEAHRIQEKLCAQN	CCDC171	106	Q6TFL3
QAQEREVIQKECAHI	AP1G2	21	O75843
VQHRQLKDNTCVVEF	ACACA	1166	Q13085
QQQRFHEICSNLVKT	ARL6IP1	101	Q15041
ADNQEKAILNIQARC	ANKRD36	1741	A6QL64
NQEKAILNIQARCDA	ANKRD36B	1181	Q8N2N9
KSVEQEVVQSQLNHC	DMD	1491	P11532
IHAIAQCTQKLNEAN	DNHD1	826	Q96M86
QQLEECRHQENLIEN	DNHD1	3191	Q96M86
NAQVQRNKQHEVEEA	ACAP2	141	Q15057
HCRQILNYVNQAVKE	ARHGEF12	966	Q9NZN5
DQLLSIRCQHQEQVE	MTUS2	1121	Q5JR59
NKNHAQVVAQARLIV	PGK2	321	P07205
LQQQCEQTVRILHAK	RBPJL	61	Q9UBG7
KQQVDNVAQCHIQLA	PSTPIP2	81	Q9H939
EVCHLLEQERQQHNQ	RABEP1	261	Q15276
IEHCQEKQLDENANV	CYP1A1	286	P04798
QQQQQHIECVVCGDK	NR2F2	71	P24468
FHQQCKRNELVIRVQ	G6PD	381	P11413
RAQIEQVIANCEHKN	NUP205	1206	Q92621
QVIANCEHKNLRGQT	NUP205	1211	Q92621
QRIQEFCNLHQSKEE	NUBP1	301	P53384
CIGNENNQRAVREHK	ANKAR	851	Q7Z5J8
CLHVACVVQQKDARQ	CCNC	201	P24863
NQEKAILNIQARCDA	ANKRD36C	1606	Q5JPF3
NKNIIAEHEIRNISC	ANKS1B	1121	Q7Z6G8
QAQIVHAGQACVVKE	MDGA1	26	Q8NFP4
VILHQNHEEDNCVQR	ETV6	146	P41212
VALCVRQHARQQDKE	PTPRN	596	Q16849
CDRKAVHQIDQLQRE	MXD1	111	Q05195
VQQRHILESEKCQLQ	MAFA	276	Q8NHW3
LQLHRQCVVCKQADE	MAGT1	81	Q9H0U3
KSNHEQEVNTLRCQL	KRT31	191	Q15323
SQQCVFRDQEPKIHN	LRIF1	521	Q5T3J3
LQLCQCVEQHIKENT	DST	791	Q03001
EVERQAQHTLKDCLQ	KRT37	331	O76014
NAKLQQENEQHSLVC	CFAP58	281	Q5T655
HSLVCEQLSQENQQK	CFAP58	291	Q5T655
QCKNVQDAIADAEQR	KRT2	416	P35908
EVERQAQHTLKDCLQ	KRT38	331	O76015
VEKACQLVNRQDRAH	DUOX2	1526	Q9NRD8
HNQLQELKGNIRVFC	KIFC1	301	Q9BW19
QCDRRLTLQQKEHEQ	KIF27	1161	Q86VH2
QLVECVKTRELQHQE	PLVAP	196	Q9BX97
VLKVCGQEEVLQNNH	PIK3C2A	471	O00443
QIENQHRAVDQVIKA	PIK3C2A	566	O00443
ELERQENVLVICHQA	PFKFB3	376	Q16875
QNQHTNALKRCEEVA	DLG5	206	Q8TDM6
QAKDIVQHCTQCQVL	HERVK_113	616	P63132
ELLCLKQNHEQEVNT	KRT33A	186	O76009
KQNHEQEVNTLRCQL	KRT33A	191	O76009
QCKEEVSIQRQINHP	RSKR	151	Q96LW2
AVRNCLECQQHSQLK	LRBA	1451	P50851
NEVHVAKIQQIEREC	MSANTD3	216	Q96H12
AREHAQKCQQQQREA	NFKBIL1	206	Q9UBC1
LERHQKEECQDRVTQ	CYHR1	151	Q6ZMK1
DIEIVNHKTNDRCQL	OSBP2	701	Q969R2
QAKDIVQHCTQCQIL	ERVK-7	616	P63135
QAKDIVQHCTQCQVL	ERVK-6	616	Q9BXR3
QLQSQLAHQTEQKEC	MACF1	1531	Q9UPN3
KAEDRGQCNHVRINQ	ITGB7	421	P26010
RTQEQCVHNETKNEL	OPA1	781	O60313
QAKDIVQHCTQCQVL	ERVK-18	616	Q9QC07
QVVKVLHDAQQQCRD	ILVBL	596	A1L0T0
QLNDNRQLAHVEAVC	KCNB2	226	Q92953
QEANCKNHRVNRVVF	CORO2B	216	Q9UQ03
NERVAALHNDQEACK	CENPF	2451	P49454
CERAQNLKDHLIQFQ	DNAH3	676	Q8TD57
KGLNVQEQLEHTRNC	CHD2	1491	O14647
EQLTNLEHRCQKAEV	CROCC2	1496	H7BZ55
CQDVNHNKVIETNRE	DSP	646	P15924
KEAQLLVIENEVCNH	LPA	1956	P08519
EQQEQLLACKLNQHD	CEP162	1006	Q5TB80
HQREIEKLLCQNAVE	CEP162	1226	Q5TB80
QHQAEVQIARKLQCI	BMF	126	Q96LC9
VQIARKLQCIADQFH	BMF	131	Q96LC9
LIKYNQQRVHELENC	LYST	1841	Q99698
VQKGECHVNFVRKEQ	MANBA	171	O00462
VSQQVQCIQEALREH	DYNC1H1	1971	Q14204
LHQKETNQDVQCNRF	ESCO1	351	Q5FWF5
QEQEEALKQCREQHA	GRIPAP1	541	Q4V328
CAQVKRLENNHAQLL	CAVIN2	136	O95810
LQAQQDAVNIVCHSK	PSMD4	26	P55036
NHNCIKHLRSVVQQQ	RNF41	131	Q9H4P4
LCQQLQAEQAAAEKR	NUMA1	1366	Q14980
CQVAKQHVQDGRKER	REXO1	1026	Q8N1G1
ENRKCAGNHIIQTQL	THADA	176	Q6YHU6
LLQHQICKEVQAEQE	SPAG8	356	Q99932
EQEKVVTNCQERIQH	URI1	36	O94763
LQVENENHCDFVKLR	SEPTIN14	271	Q6ZU15
EVENQAHCDFVKLRN	SEPTIN5	271	Q99719
QKHVSRQDTLQQCQA	SYNE1	4036	Q8NF91
HFKDGREKTVNQQCQ	SYNE2	1496	Q8WXH0
RQDCHEKIRVLSQQA	ADSL	396	P30566
VAGEICHKVQELQQQ	SGSM2	81	O43147
NIQDHNVKDFLCQIE	HERC2P3	126	Q9BVR0
LTREQQQCHKELQQA	IQANK1	321	A8MXQ7
VLIQAAQLCREKQHT	SRP72	341	O76094
ERQQQLQEELQCHEA	CCDC136	441	Q96JN2
FLENEHQQLQAKIEC	TRAF3IP3	366	Q9Y228
HQQLQAKIECLQGDR	TRAF3IP3	371	Q9Y228
QNVSQKDCNCLHVVE	TMEM9	46	Q9P0T7
QHKQCLEEAQLENET	VIPR1	46	P32241
HCQAVLKQLNEQRLS	ZBTB11	196	O95625
HCKDSQQQIVCIAEQ	REV3L	1421	O60673
QQQIVCIAEQSKHSE	REV3L	1426	O60673
EQIFLLHRAQAQCEK	PTH1R	36	Q03431
EQQARRDCQEQAKIA	TPR	1061	P12270
RDCQEQAKIAVEAQN	TPR	1066	P12270
NRHEKVQENCIDLVG	SF3B1	1026	O75533
CAELHQNVNVKNIII	VPS35	286	Q96QK1
IQENEDKHSRQAACI	RBAK	91	Q9NYW8
ARVCHLCIEQQQLDK	RASGEF1C	81	Q8N431
LAKLIQTCQHVEVNA	MID1	241	O15344
ISVLHQNVLCKQEQV	FGD6	361	Q6ZV73
QAKDIVQHCTQCQVL	ERVK-10	616	P10266
QAKDIVQHCTQCQVL	ERVK-8	616	P63133
KALQHCEELIQQYNR	WAPL	886	Q7Z5K2
QAKDIVQHCTQCQVL	ERVK-11	616	Q9UQG0
CAQRIAEQQKAQAEV	PLEC	1156	Q15149
ICTTQQVKHNNECRD	GTF3C4	256	Q9UKN8
SIENHCSIQQQRKIA	PLCH1	391	Q4KWH8
AEFVEKVRQSNQACH	TTC28	56	Q96AY4
QENQGCIRKVTVSHQ	ZNF140	131	P52738
QQQLVQSCKAVADHI	TLN2	951	Q9Y4G6
IAQVQVLRDQLCKHC	USP34	71	Q70CQ2
VTKNHVLCQEVQRNF	TRANK1	1151	O15050
QDLLHRCFQEQEQKS	TET2	876	Q6N021
REKRAACEQLHQQQQ	PURA	286	Q00577
EIQAQCNKVLRHFAD	TTI1	346	O43156
KQNHEQEVNTLRCQL	KRT33B	191	Q14525
LNSHNCLVRENKNVV	LIMK1	461	P53667
EKRHLQVNVTNPVQC	MYO1D	956	O94832