Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	UDP-glucose:glycoprotein glucosyltransferase activity	UGGT1 UGGT2	2.43e-05	2	99	2	GO:0003980
GeneOntologyBiologicalProcess	UDP-glucosylation	UGGT1 UGGT2	2.19e-05	2	97	2	GO:0097359
Domain	UDP-g_GGtrans	UGGT1 UGGT2	2.56e-05	2	95	2	IPR009448
Domain	UDP-g_GGTase	UGGT1 UGGT2	2.56e-05	2	95	2	PF06427
Domain	Unchr_dom_Cys-rich	KCP FCGBP MUC5AC	3.51e-05	13	95	3	IPR014853
Domain	C8	KCP FCGBP MUC5AC	3.51e-05	13	95	3	SM00832
Domain	TIL_dom	KCP FCGBP MUC5AC	4.46e-05	14	95	3	IPR002919
Domain	VWD	KCP FCGBP MUC5AC	6.80e-05	16	95	3	SM00216
Domain	VWF_type-D	KCP FCGBP MUC5AC	6.80e-05	16	95	3	IPR001846
Domain	VWFD	KCP FCGBP MUC5AC	6.80e-05	16	95	3	PS51233
Domain	VWD	KCP FCGBP MUC5AC	6.80e-05	16	95	3	PF00094
Domain	VWC_out	KCP FCGBP MUC5AC	1.16e-04	19	95	3	SM00215
Domain	CABIT	GAREM2 GAREM1	1.53e-04	4	95	2	PF12736
Domain	Notch	NOTCH2 NOTCH4	1.53e-04	4	95	2	IPR008297
Domain	NODP	NOTCH2 NOTCH4	1.53e-04	4	95	2	PF07684
Domain	Notch_NODP_dom	NOTCH2 NOTCH4	1.53e-04	4	95	2	IPR011656
Domain	CABIT_dom	GAREM2 GAREM1	1.53e-04	4	95	2	IPR025946
Domain	Notch_NOD_dom	NOTCH2 NOTCH4	1.53e-04	4	95	2	IPR010660
Domain	DUF1908	MAST4 MAST1	1.53e-04	4	95	2	PF08926
Domain	NOD	NOTCH2 NOTCH4	1.53e-04	4	95	2	PF06816
Domain	MA_Ser/Thr_Kinase_dom	MAST4 MAST1	1.53e-04	4	95	2	IPR015022
Domain	MAST_pre-PK_dom	MAST4 MAST1	1.53e-04	4	95	2	IPR023142
Domain	NOD	NOTCH2 NOTCH4	1.53e-04	4	95	2	SM01338
Domain	NODP	NOTCH2 NOTCH4	1.53e-04	4	95	2	SM01339
Domain	-	MAST4 MAST1	1.53e-04	4	95	2	1.20.1480.20
Domain	Lipase_panc	PNLIP PNLIPRP2	1.53e-04	4	95	2	IPR002331
Domain	LNR	NOTCH2 NOTCH4	2.53e-04	5	95	2	PS50258
Domain	Notch_dom	NOTCH2 NOTCH4	5.29e-04	7	95	2	IPR000800
Domain	Notch	NOTCH2 NOTCH4	5.29e-04	7	95	2	PF00066
Domain	NL	NOTCH2 NOTCH4	5.29e-04	7	95	2	SM00004
Domain	LRRCT	TRIL LRIG3 LRRN3	5.68e-04	32	95	3	PF01463
Domain	VWC	KCP FCGBP MUC5AC	9.45e-04	38	95	3	SM00214
Domain	Lipase/vitellogenin	PNLIP PNLIPRP2	1.12e-03	10	95	2	IPR013818
Domain	TAG_lipase	PNLIP PNLIPRP2	1.12e-03	10	95	2	IPR000734
Domain	Lipase_LIPH	PNLIP PNLIPRP2	1.12e-03	10	95	2	IPR016272
Domain	Lipase	PNLIP PNLIPRP2	1.12e-03	10	95	2	PF00151
Domain	Lipase_N	PNLIP PNLIPRP2	1.12e-03	10	95	2	IPR033906
Domain	VWF_dom	KCP FCGBP MUC5AC	1.27e-03	42	95	3	IPR001007
Domain	TIL	FCGBP MUC5AC	1.63e-03	12	95	2	PF01826
Domain	C8	FCGBP MUC5AC	1.63e-03	12	95	2	PF08742
Domain	Calpain_cysteine_protease	CAPN8 CAPN15	2.24e-03	14	95	2	IPR022684
Domain	CysPc	CAPN8 CAPN15	2.57e-03	15	95	2	SM00230
Domain	Peptidase_C2_calpain_cat	CAPN8 CAPN15	2.57e-03	15	95	2	IPR001300
Domain	Peptidase_C2	CAPN8 CAPN15	2.57e-03	15	95	2	PF00648
Domain	CALPAIN_CAT	CAPN8 CAPN15	2.57e-03	15	95	2	PS50203
Domain	AGC-kinase_C	CIT MAST4 MAST1	2.91e-03	56	95	3	IPR000961
Domain	AGC_KINASE_CTER	CIT MAST4 MAST1	2.91e-03	56	95	3	PS51285
Domain	S_TK_X	CIT MAST4 MAST1	2.91e-03	56	95	3	SM00133
Domain	LH2	PNLIP PNLIPRP2	3.71e-03	18	95	2	SM00308
Domain	PLAT	PNLIP PNLIPRP2	5.05e-03	21	95	2	PS50095
Domain	-	PNLIP PNLIPRP2	5.05e-03	21	95	2	2.60.60.20
Domain	PLAT	PNLIP PNLIPRP2	5.05e-03	21	95	2	PF01477
Domain	PLAT/LH2_dom	PNLIP PNLIPRP2	5.05e-03	21	95	2	IPR001024
Domain	ConA-like_dom	SHBG LAMA5 PTPRU LMAN1L NBEAL2	5.22e-03	219	95	5	IPR013320
Domain	PDZ	SHROOM2 RGS12 MAST4 MAST1	5.83e-03	141	95	4	PF00595
Domain	PDZ	SHROOM2 RGS12 MAST4 MAST1	6.90e-03	148	95	4	SM00228
Domain	EGF	LAMA5 FCGBP ASTN1 NOTCH2 NOTCH4	7.00e-03	235	95	5	SM00181
Pathway	REACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3	NOTCH2 NOTCH4	1.95e-04	5	63	2	M27411
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTSL1 MUC5AC NOTCH2 NOTCH4	2.38e-04	68	63	4	M27303
Pathway	REACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM	NOTCH2 NOTCH4	2.91e-04	6	63	2	M27068
Pathway	REACTOME_DIGESTION_OF_DIETARY_LIPID	PNLIP PNLIPRP2	2.91e-04	6	63	2	MM14738
Pubmed	E3 ubiquitin ligase FBXW7 balances airway cell fates.	MUC5AC NOTCH2 NOTCH4 FOXJ1	4.34e-07	22	99	4	34998785
Pubmed	Notch signaling prevents mucous metaplasia in mouse conducting airways during postnatal development.	MUC5AC NOTCH2 NOTCH4 FOXJ1	1.03e-06	27	99	4	21791528
Pubmed	Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes.	ADAMTSL1 NLRP6 FCGBP DCLK1 GULP1	4.36e-06	84	99	5	15203218
Pubmed	Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.	MUC5AC NOTCH2 NOTCH4 FOXJ1	5.77e-06	41	99	4	22675208
Pubmed	Evaluation of Lama5 as a candidate for the mouse ragged (Ra) mutation.	LAMA5 SOX18	8.02e-06	2	99	2	9735344
Pubmed	Notch receptors and hematopoiesis.	NOTCH2 NOTCH4	8.02e-06	2	99	2	11532344
Pubmed	Two homologues encoding human UDP-glucose:glycoprotein glucosyltransferase differ in mRNA expression and enzymatic activity.	UGGT1 UGGT2	8.02e-06	2	99	2	10694380
Pubmed	Kinetic properties of mouse pancreatic lipase-related protein-2 suggest the mouse may not model human fat digestion.	PNLIP PNLIPRP2	8.02e-06	2	99	2	21382969
Pubmed	Progesterone regulates the expression and activity of two mouse isoforms of the glycoprotein folding sensor UDP-Glc: glycoprotein glucosyltransferase (UGGT).	UGGT1 UGGT2	8.02e-06	2	99	2	24140206
Pubmed	Quantitative glycoproteomics reveals cellular substrate selectivity of the ER protein quality control sensors UGGT1 and UGGT2.	UGGT1 UGGT2	8.02e-06	2	99	2	33320095
Pubmed	notch2, notch4 gene polymorphisms in psoriasis vulgaris.	NOTCH2 NOTCH4	8.02e-06	2	99	2	23587900
Pubmed	Effects of domain composition on catalytic activity of human UDP-glucose:glycoprotein glucosyltransferases.	UGGT1 UGGT2	8.02e-06	2	99	2	27496766
Pubmed	The autophagy protein, FIP200 (RB1CC1) mediates progesterone responses governing uterine receptivity and decidualization†.	RB1CC1 PGR	8.02e-06	2	99	2	31901086
Pubmed	The noncatalytic portion of human UDP-glucose: glycoprotein glucosyltransferase I confers UDP-glucose binding and transferase function to the catalytic domain.	UGGT1 UGGT2	8.02e-06	2	99	2	12913004
Pubmed	Both isoforms of human UDP-glucose:glycoprotein glucosyltransferase are enzymatically active.	UGGT1 UGGT2	8.02e-06	2	99	2	24415556
Pubmed	Inflammation dysregulates Notch signaling in endothelial cells: implication of Notch2 and Notch4 to endothelial dysfunction.	NOTCH2 NOTCH4	8.02e-06	2	99	2	20643108
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SZT2 LAMA5 LRIG3 MAST4 USP38 NBEAL2 ZNF516 RNF10 ARAP1	2.10e-05	529	99	9	14621295
Pubmed	Pancreatic lipase and its related proteins: where are we now?	PNLIP PNLIPRP2	2.40e-05	3	99	2	38081381
Pubmed	Differential expression of Notch genes in human osteoblastic cells.	NOTCH2 NOTCH4	2.40e-05	3	99	2	11836628
Pubmed	Two novel human pancreatic lipase related proteins, hPLRP1 and hPLRP2. Differences in colipase dependence and in lipase activity.	PNLIP PNLIPRP2	2.40e-05	3	99	2	1379598
Pubmed	Genetic mapping of the gene for androgen-binding protein/sex hormone-binding globulin to mouse chromosome 11.	WNT3 SHBG	2.40e-05	3	99	2	2013230
Pubmed	Resveratrol increases anti-aging Klotho gene expression via the activating transcription factor 3/c-Jun complex-mediated signaling pathway.	KL ATF3	2.40e-05	3	99	2	24911970
Pubmed	Integrity of intracellular domain of Notch ligand is indispensable for cleavage required for release of the Notch2 intracellular domain.	NOTCH2 NOTCH4	2.40e-05	3	99	2	11823422
Pubmed	Notch signaling: cell fate control and signal integration in development.	NOTCH2 NOTCH4	2.40e-05	3	99	2	10221902
Pubmed	Cloning of an interleukin-4 inducible gene from cytotoxic T lymphocytes and its identification as a lipase.	PNLIP PNLIPRP2	2.40e-05	3	99	2	2302735
Pubmed	Association between the 15-kDa selenoprotein and UDP-glucose:glycoprotein glucosyltransferase in the endoplasmic reticulum of mammalian cells.	UGGT1 UGGT2	2.40e-05	3	99	2	11278576
Pubmed	Loss of function of the maternal membrane oestrogen receptor ERα alters expansion of trophoblast cells and impacts mouse fertility.	PGR NOTCH2 NOTCH4	3.80e-05	23	99	3	36239412
Pubmed	Transient Expression of Fez Family Zinc Finger 2 Protein Regulates the Brn3b Gene in Developing Retinal Ganglion Cells.	POU4F2 NEFH	4.79e-05	4	99	2	26861874
Pubmed	Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.	NOTCH2 NOTCH4	4.79e-05	4	99	2	28061457
Pubmed	The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors.	NOTCH2 NOTCH4	4.79e-05	4	99	2	24145721
Pubmed	A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.	NOTCH2 NOTCH4	4.79e-05	4	99	2	20069356
Pubmed	Expression and clinical significance of Notch receptors in human renal cell carcinoma.	NOTCH2 NOTCH4	4.79e-05	4	99	2	19404845
Pubmed	Notch signaling pathway regulates the growth and the expression of inflammatory cytokines in mouse basophils.	NOTCH2 NOTCH4	4.79e-05	4	99	2	28669409
Pubmed	Porcupine inhibitor suppresses paracrine Wnt-driven growth of Rnf43;Znrf3-mutant neoplasia.	WNT3 ZNRF3	4.79e-05	4	99	2	26023187
Pubmed	Evolutionary analysis of vertebrate Notch genes.	NOTCH2 NOTCH4	4.79e-05	4	99	2	11466531
Pubmed	Abnormal expression pattern of Notch receptors, ligands, and downstream effectors in the dorsolateral prefrontal cortex and amygdala of suicidal victims.	NOTCH2 NOTCH4	4.79e-05	4	99	2	24151014
Pubmed	Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress.	KL ATF3	4.79e-05	4	99	2	31907991
Pubmed	Characterization and developmental expression of the amphioxus homolog of Notch (AmphiNotch): evolutionary conservation of multiple expression domains in amphioxus and vertebrates.	NOTCH2 NOTCH4	4.79e-05	4	99	2	11401408
Pubmed	Loss of lysophosphatidylcholine acyltransferase 1 leads to photoreceptor degeneration in rd11 mice.	LPCAT1 POU4F2	4.79e-05	4	99	2	20713727
Pubmed	Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation.	NOTCH2 NOTCH4	4.79e-05	4	99	2	10194420
Pubmed	Functional conservation of mouse Notch receptor family members.	NOTCH2 NOTCH4	4.79e-05	4	99	2	8898100
Pubmed	Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members.	NOTCH2 NOTCH4	4.79e-05	4	99	2	11459941
Pubmed	Notch signaling drives development of Barrett's metaplasia from Dclk1-positive epithelial tuft cells in the murine gastric mucosa.	DCLK1 NOTCH2	4.79e-05	4	99	2	33627749
Pubmed	A brain-specific Grb2-associated regulator of extracellular signal-regulated kinase (Erk)/mitogen-activated protein kinase (MAPK) (GAREM) subtype, GAREM2, contributes to neurite outgrowth of neuroblastoma cells by regulating Erk signaling.	GAREM2 GAREM1	4.79e-05	4	99	2	24003223
Pubmed	Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias.	NOTCH2 NOTCH4	4.79e-05	4	99	2	18184405
Pubmed	Polypeptide N-acetylgalactosaminyltransferase 18 retains in endoplasmic reticulum depending on its luminal regions interacting with ER resident UGGT1, PLOD3 and LPCAT1.	LPCAT1 UGGT1	4.79e-05	4	99	2	33909026
Pubmed	Notch signaling in the mammalian central nervous system: insights from mouse mutants.	NOTCH2 NOTCH4	4.79e-05	4	99	2	15917835
Pubmed	Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma.	NOTCH2 NOTCH4	4.79e-05	4	99	2	23444212
Pubmed	Deregulated expression of Notch receptors in human hepatocellular carcinoma.	NOTCH2 NOTCH4	4.79e-05	4	99	2	17920003
Pubmed	Excess neuropeptides in lung signal through endothelial cells to impair gas exchange.	MUC5AC NOTCH2 FOXJ1	6.23e-05	27	99	3	35303432
Pubmed	EGFL7 is expressed in bone microenvironment and promotes angiogenesis via ERK, STAT3, and integrin signaling cascades.	PGR NOTCH2 NOTCH4	7.75e-05	29	99	3	24909139
Pubmed	Uterine Rbpj is required for embryonic-uterine orientation and decidual remodeling via Notch pathway-independent and -dependent mechanisms.	PGR NOTCH2 NOTCH4	7.75e-05	29	99	3	24971735
Pubmed	Notch signaling in stomach epithelial stem cell homeostasis.	MUC5AC NOTCH2 NOTCH4	7.75e-05	29	99	3	21402740
Pubmed	Expression patterns of Notch receptors and their ligands Jagged and Delta in human placenta.	NOTCH2 NOTCH4	7.98e-05	5	99	2	21726900
Pubmed	Notch and MAML-1 complexation do not detectably alter the DNA binding specificity of the transcription factor CSL.	NOTCH2 NOTCH4	7.98e-05	5	99	2	21124806
Pubmed	Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dll4).	NOTCH2 NOTCH4	7.98e-05	5	99	2	23675950
Pubmed	MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.	NOTCH2 NOTCH4	7.98e-05	5	99	2	11101851
Pubmed	Augmented Wnt signaling in a mammalian model of accelerated aging.	WNT3 KL	7.98e-05	5	99	2	17690294
Pubmed	Tissue-specific expression of the human laminin alpha5-chain, and mapping of the gene to human chromosome 20q13.2-13.3 and to distal mouse chromosome 2 near the locus for the ragged (Ra) mutation.	LAMA5 SOX18	7.98e-05	5	99	2	9271224
Pubmed	The gene for C10, a member of the beta-chemokine family, is located on mouse chromosome 11 and contains a novel second exon not found in other chemokines.	WNT3 SHBG	7.98e-05	5	99	2	8216854
Pubmed	Functional redundancy of the Notch gene family during mouse embryogenesis: analysis of Notch gene expression in Notch3-deficient mice.	NOTCH2 NOTCH4	7.98e-05	5	99	2	15882997
Pubmed	Association of Notch pathway down-regulation with Triple Negative/Basal-like breast carcinomas and high tumor-infiltrating FOXP3+ Tregs.	NOTCH2 NOTCH4	7.98e-05	5	99	2	27118257
Pubmed	Uterine Notch2 facilitates pregnancy recognition and corpus luteum maintenance via upregulating decidual Prl8a2.	PGR NOTCH2	7.98e-05	5	99	2	34460816
Pubmed	RBP-L, a transcription factor related to RBP-Jkappa.	NOTCH2 NOTCH4	1.19e-04	6	99	2	9111338
Pubmed	Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease.	NOTCH2 NOTCH4	1.19e-04	6	99	2	20870902
Pubmed	Characterization of Notch receptor expression in the developing mammalian heart and liver.	NOTCH2 NOTCH4	1.19e-04	6	99	2	12244553
Pubmed	Hairy-related transcription factors inhibit Notch-induced smooth muscle alpha-actin expression by interfering with Notch intracellular domain/CBF-1 complex interaction with the CBF-1-binding site.	NOTCH2 NOTCH4	1.19e-04	6	99	2	18239137
Pubmed	Notch4 Negatively Regulates the Inflammatory Response to Mycobacterium tuberculosis Infection by Inhibiting TAK1 Activation.	NOTCH2 NOTCH4	1.19e-04	6	99	2	29228365
Pubmed	The Wilms' tumor gene Wt1 is required for normal development of the retina.	POU4F2 NEFH	1.19e-04	6	99	2	11889045
Pubmed	Genome-wide scan revealed that polymorphisms in the PNPLA3, SAMM50, and PARVB genes are associated with development and progression of nonalcoholic fatty liver disease in Japan.	PTPRU DCLK1	1.19e-04	6	99	2	23535911
Pubmed	Chromatin remodeling of prostaglandin signaling in smooth muscle enables mouse embryo passage through the female reproductive tract.	PGR FOXJ1	1.19e-04	6	99	2	37714160
Pubmed	Postsynaptic CaV1.1-driven calcium signaling coordinates presynaptic differentiation at the developing neuromuscular junction.	NEFH SLC18A3	1.19e-04	6	99	2	31804576
Pubmed	Epidermal growth factor-like domain 7 (EGFL7) modulates Notch signalling and affects neural stem cell renewal.	NOTCH2 NOTCH4	1.19e-04	6	99	2	19503073
Pubmed	Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways.	NOTCH2 NOTCH4	1.19e-04	6	99	2	18299578
Pubmed	Ribosomal collision is not a prerequisite for ZNF598-mediated ribosome ubiquitination and disassembly of ribosomal complexes by ASCC.	RNF10 ZNF598	1.19e-04	6	99	2	38366554
Pubmed	POU domain factor Brn-3b is required for the development of a large set of retinal ganglion cells.	POU4F2 NEFH	1.19e-04	6	99	2	8632990
Pubmed	Cloning and functional characterization of the murine mastermind-like 1 (Maml1) gene.	NOTCH2 NOTCH4	1.19e-04	6	99	2	15019995
Pubmed	Notch controls the magnitude of T helper cell responses by promoting cellular longevity.	NOTCH2 NOTCH4	1.19e-04	6	99	2	22615412
Pubmed	Notch lineages and activity in intestinal stem cells determined by a new set of knock-in mice.	NOTCH2 NOTCH4	1.19e-04	6	99	2	21991352
Pubmed	Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.	SOX18 MFRP NEFH ADAD2 RNF10	1.33e-04	171	99	5	28700664
Pubmed	Human ligands of the Notch receptor.	NOTCH2 NOTCH4	1.67e-04	7	99	2	10079256
Pubmed	Substituting mouse transcription factor Pou4f2 with a sea urchin orthologue restores retinal ganglion cell development.	POU4F2 NEFH	1.67e-04	7	99	2	26962139
Pubmed	Mapping of the mouse 86-kDa heat-shock protein expressed gene (Hsp86-1) on chromosome 12 and related genes on chromosomes 3, 4, 9, and 11.	WNT3 SHBG	1.67e-04	7	99	2	1916807
Pubmed	The distribution of Notch receptors and their ligands during articular cartilage development.	NOTCH2 NOTCH4	1.67e-04	7	99	2	12846471
Pubmed	Murine notch homologs (N1-4) undergo presenilin-dependent proteolysis.	NOTCH2 NOTCH4	1.67e-04	7	99	2	11518718
Pubmed	Requirement for math5 in the development of retinal ganglion cells.	POU4F2 NEFH	1.67e-04	7	99	2	11156601
Pubmed	Molecular cloning and chromosomal mapping of the mouse gene encoding cyclin-dependent kinase 5 regulatory subunit p35.	WNT3 SHBG	1.67e-04	7	99	2	8661152
Pubmed	Tissue expression patterns identify mouse cilia genes.	LRCH3 CFAP65 CABCOCO1 FOXJ1	1.68e-04	96	99	4	17971504
Pubmed	Exome sequencing supports a de novo mutational paradigm for schizophrenia.	RB1CC1 RGS12 CFAP65	2.05e-04	40	99	3	21822266
Pubmed	Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients.	NOTCH2 NOTCH4	2.22e-04	8	99	2	22156581
Pubmed	In vivo analysis of Lrig genes reveals redundant and independent functions in the inner ear.	NEFH LRIG3	2.22e-04	8	99	2	24086156
Pubmed	Roles for laminin in embryogenesis: exencephaly, syndactyly, and placentopathy in mice lacking the laminin alpha5 chain.	LAMA5 SOX18	2.22e-04	8	99	2	9852162
Pubmed	Notch1 and Jagged1 expression by the developing pulmonary vasculature.	NOTCH2 NOTCH4	2.22e-04	8	99	2	12242716
Pubmed	Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear.	NOTCH2 NOTCH4	2.22e-04	8	99	2	9858718
Pubmed	Sensory-motor deficits and neurofilament disorganization in gigaxonin-null mice.	NEFH SLC18A3	2.22e-04	8	99	2	21486449
Pubmed	A GO catalogue of human DNA-binding transcription factors.	ZNF775 ZNF469 ZNF512	2.37e-04	42	99	3	34673265
Pubmed	Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach.	LAMA5 HBP1 USP38 NOTCH2	2.46e-04	106	99	4	18654987
Pubmed	Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.	NOTCH2 NOTCH4	2.85e-04	9	99	2	11118901
Pubmed	Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.	NOTCH2 NOTCH4	2.85e-04	9	99	2	16245338
Pubmed	Essential Roles of Tbr1 in the Formation and Maintenance of the Orientation-Selective J-RGCs and a Group of OFF-Sustained RGCs in Mouse.	POU4F2 NEFH	2.85e-04	9	99	2	30995485
GeneFamily	UDP-glucose glycoprotein glucosyltransferases	UGGT1 UGGT2	1.31e-05	2	66	2	440
GeneFamily	C2 domain containing\|Calpains	CAPN8 CAPN15	1.34e-03	15	66	2	975
GeneFamily	PDZ domain containing	SHROOM2 RGS12 MAST4 MAST1	2.31e-03	152	66	4	1220
GeneFamily	Lipases\|Arylacetamide deacetylase family	PNLIP PNLIPRP2	2.89e-03	22	66	2	464
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ADAMTSL1 CAPN8 FCGBP MAST4 MUC5AC GULP1	2.82e-06	177	99	6	779ba86f53650772755b52460be03f18bb204e55
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS-Secretory\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ADAMTSL1 CAPN8 FCGBP MAST4 MUC5AC GULP1	2.82e-06	177	99	6	0f210cfb61b873c5fd77dc17eadf4d017306500e
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Adult / Lineage, Cell type, age group and donor	LPCAT1 CIT CAPN8 LRIG3 MAST4 GAREM1	3.64e-06	185	99	6	673f0c688ae6984bc8027df2da335787924f4137
ToppCell	facs-Heart-LV-24m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGPP2 PGR CAPN8 FCGBP KRTCAP3 ATF3	3.64e-06	185	99	6	a835f821a5e6568d648df831ec4c2d0048d67093
ToppCell	facs-Heart-LV-24m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGPP2 PGR CAPN8 FCGBP KRTCAP3 ATF3	3.64e-06	185	99	6	386b08bcb304db543e3c5ff75f85e99bf0c592df
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D175\|Adult / Lineage, Cell type, age group and donor	SGPP2 CAPN8 LRIG3 MAST4 ZNRF3 GAREM1	3.99e-06	188	99	6	ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D231\|Adult / Lineage, Cell type, age group and donor	LPCAT1 SGPP2 CAPN8 MAST4 ZNRF3 GAREM1	4.11e-06	189	99	6	dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCell	Epithelial-alveolar_epithelial_cell_type_2\|World / Lineage, Cell type, age group and donor	LPCAT1 SGPP2 CAPN8 MAST4 ZNRF3 GAREM1	4.50e-06	192	99	6	58c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LPCAT1 SGPP2 CAPN8 MAST4 ZNRF3 GAREM1	4.50e-06	192	99	6	cc9911e182a289779a2612bc213daae5607689e7
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2\|Adult / Lineage, Cell type, age group and donor	LPCAT1 SGPP2 CAPN8 MAST4 ZNRF3 GAREM1	4.64e-06	193	99	6	738f4f0a9ddde2432b429ab46838e353b1790589
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LPCAT1 SGPP2 CAPN8 MAST4 ZNRF3 GAREM1	5.37e-06	198	99	6	f948391296c261c473d339069a6d0f20ccd6f38f
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LPCAT1 SGPP2 CAPN8 MAST4 ZNRF3 GAREM1	5.37e-06	198	99	6	2e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCell	10x5'-Lung-Myeloid_Mac-Intestinal_macrophages\|Lung / Manually curated celltypes from each tissue	ZNF775 KLF15 PTPRU ARHGEF17 FCGBP	1.59e-05	141	99	5	7671d300b1722711fd2d8034b96a3aa7e3ccb560
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_1\|343B / Donor, Lineage, Cell class and subclass (all cells)	PDE12 MAST4 SMG9 METTL8 FOXJ1	2.51e-05	155	99	5	a4ff78e2efc6fe9a513bb2b64e5848f2ce65a09f
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LPCAT1 LAMA5 CAPN8 LRIG3 MAST4	2.83e-05	159	99	5	8680b054622f573a82b1625fb93c2d5db81d1034
ToppCell	Thalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Chrnb3_(interneuron,_Lateral_Geniculate_Nucleus__(LGN))-\|Thalamus / BrainAtlas - Mouse McCarroll V32	PNLIPRP2 POU4F2 MFRP LMAN1L	2.92e-05	79	99	4	d4f9297084aea33203dd98d7f6f837b6eb00b6c3
ToppCell	Thalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Chrnb3_(interneuron,_Lateral_Geniculate_Nucleus__(LGN))--\|Thalamus / BrainAtlas - Mouse McCarroll V32	PNLIPRP2 POU4F2 MFRP LMAN1L	2.92e-05	79	99	4	5c37af70dca7e9847f44d7f5969d4b06c32b4ca0
ToppCell	Thalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Chrnb3_(interneuron,_Lateral_Geniculate_Nucleus__(LGN))\|Thalamus / BrainAtlas - Mouse McCarroll V32	PNLIPRP2 POU4F2 MFRP LMAN1L	2.92e-05	79	99	4	75d8cbf8c7a6a4a825143f7d04a604e97bab0fe5
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231\|Adult / Lineage, Cell type, age group and donor	CIT CAPN8 LRIG3 MAST4 GAREM1	3.90e-05	170	99	5	269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DCHS2 KCP ARHGEF17 PGR NOTCH2	3.90e-05	170	99	5	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SGPP2 CAPN8 FCGBP MAST4 WDR62	4.12e-05	172	99	5	63a91974b12c3f7f0c6bf66c30088d7fc07f5cea
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFAP65 MLXIPL FCGBP KRTCAP3 MUC5AC	4.35e-05	174	99	5	e7cca4b6a3935fad61cf2a3d9984ab1ffa1a9447
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet-Goblet_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFAP65 MLXIPL FCGBP KRTCAP3 MUC5AC	4.35e-05	174	99	5	ad5b56f0ace6455c033834b931ec870cc0dc9290
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SCG5 WNT3 CSMD2 NEFH KL	4.47e-05	175	99	5	8362a46f5804333baa84cd56d450bc147f372a7e
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SCG5 WNT3 CSMD2 NEFH KL	4.47e-05	175	99	5	8b4c62e608f0ec84e563bbf0ebffe3ed44085298
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCHS2 ADAMTSL1 SGPP2 PTPRU KL	4.72e-05	177	99	5	bde307e67ad8e48a5ff4c0827015f4688f6b3e46
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCHS2 ADAMTSL1 SGPP2 PTPRU KL	4.98e-05	179	99	5	7954c0026754ab869b88ab7feb13c2f27d6e272d
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	LPCAT1 SGPP2 CAPN8 MAST4 GAREM1	5.12e-05	180	99	5	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	Control-Epithelial_cells-Airway_club\|Control / group, cell type (main and fine annotations)	SGPP2 CIT CAPN8 MAST4 GAREM1	5.25e-05	181	99	5	c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l19\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SGPP2 SOX18 MAST4 RFLNB NOTCH4	5.39e-05	182	99	5	840427d1c23d60482c943ff006b14007ed44d247
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PDE12 MAST4 SMG9 METTL8 FOXJ1	5.53e-05	183	99	5	807d64deaf4e50dccf6f831f88578a6d903c1421
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LPCAT1 RGS12 FCGBP AJAP1 GRIN3B	5.53e-05	183	99	5	83592c332b1e82673f993d37c7f480befdc3dcda
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SCG5 SGPP2 MLXIPL KL GRIN3B	5.53e-05	183	99	5	d23018193b9c0806e0d1a9ac15e6392eb8e96aaf
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SGPP2 CIT CAPN8 MAST4 GAREM1	5.68e-05	184	99	5	102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCell	droplet-Mammary_Gland-nan-21m-Endothelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGPP2 SOX18 RFLNB ATF3 NOTCH4	5.82e-05	185	99	5	62cfcb0e2a9e6718e6b200dfbb1a81eaead229b5
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	PDE12 MAST4 SMG9 METTL8 FOXJ1	5.98e-05	186	99	5	76cbc3610aedf8c19c17ad5faf6ef5e8980b6af5
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SGPP2 CAPN8 MAST4 ZNRF3 GAREM1	5.98e-05	186	99	5	acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MLXIPL KL MAST4 ZNRF3 ZNF804B	5.98e-05	186	99	5	5784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADAMTSL1 LAMA5 MLXIPL NBEAL2 ATF3	6.13e-05	187	99	5	4ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ADAMTSL1 SOX18 ADAD2 KL NOTCH4	6.29e-05	188	99	5	366a2d59b9c81d8a7659749f9c07efa46b49a39a
ToppCell	3'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-arterial_capillary\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA5 SOX18 ADAD2 RFLNB NOTCH4	6.29e-05	188	99	5	be3d287ca60ec9b42be1a8eb0a9b911c16cd8c3a
ToppCell	COVID-19-lung-Secretory\|lung / Disease (COVID-19 only), tissue and cell type	SGPP2 CAPN8 LRIG3 MUC5AC GAREM1	6.44e-05	189	99	5	84d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCell	IPF-Epithelial-Basal\|IPF / Disease state, Lineage and Cell class	SGPP2 LAMA5 PTPRU LRIG3 MAST4	6.61e-05	190	99	5	ea19e9ce954f2dfde97388db9695325cd92ab88f
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LPCAT1 CAPN8 MAST4 ZNRF3 GAREM1	6.77e-05	191	99	5	a0332a4ef629510fb313ec119195c44a3f704a80
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	LPCAT1 SGPP2 CAPN8 MAST4 ZNRF3	6.77e-05	191	99	5	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	Children_(3_yrs)-Epithelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LPCAT1 CAPN8 MAST4 ZNRF3 GAREM1	6.77e-05	191	99	5	e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell	Epithelial\|World / Lineage, Cell type, age group and donor	LPCAT1 CAPN8 MAST4 ZNRF3 GAREM1	6.94e-05	192	99	5	499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	SHROOM2 LRIG3 KRTCAP3 GRIN3B GAREM1	6.94e-05	192	99	5	8899d81306770adda893b5e146df1253971754c5
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	SHROOM2 LRIG3 KRTCAP3 GRIN3B GAREM1	6.94e-05	192	99	5	5fda9a465c9f77c7fa1a3ea07a2b0374bbc23b2a
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D122\|Adult / Lineage, Cell type, age group and donor	LPCAT1 CAPN8 MLXIPL MAST4 ZNRF3	6.94e-05	192	99	5	06013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGPP2 SOX18 RGS12 RFLNB NOTCH4	6.94e-05	192	99	5	9ae05db5bfb8b9d3935c0328e6f2d489d2b1ebfd
ToppCell	IPF-Epithelial-Basal\|World / Disease state, Lineage and Cell class	SGPP2 LAMA5 PTPRU LRIG3 MAST4	6.94e-05	192	99	5	9b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGPP2 SOX18 RGS12 RFLNB NOTCH4	6.94e-05	192	99	5	a116db7dec495e5a0ba9c7537057cd1e567d7885
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGPP2 SOX18 RGS12 RFLNB NOTCH4	6.94e-05	192	99	5	66defad13bd8e79319741e43ddb056841710b1d7
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	LPCAT1 SGPP2 CAPN8 MAST4 ZNRF3	7.11e-05	193	99	5	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	(6)_Endothelial-C_(Capillary_Aerocyte_)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	LAMA5 SOX18 KL AJAP1 NOTCH4	7.11e-05	193	99	5	f7f2dc6aff02d096a282835094d26d12b3b73e61
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	LPCAT1 SGPP2 CAPN8 MAST4 ZNRF3	7.11e-05	193	99	5	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SGPP2 SOX18 AJAP1 RFLNB NOTCH4	7.29e-05	194	99	5	ea5e1bc8d9e27cabfe1fb833ca47ec0893593b12
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SGPP2 SOX18 AJAP1 RFLNB NOTCH4	7.29e-05	194	99	5	cceb7c88492bb6cd531e1c2651638da1ddf30931
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SCG5 LRRN3 SLC18A3 ASTN1 DCLK1	7.47e-05	195	99	5	5a6a5048af638872700b76b7c71a8fa3fb8d3772
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-tRG\|World / Primary Cells by Cluster	LRIG3 MAST4 ATF3 NOTCH2 FOXJ1	7.84e-05	197	99	5	61749ccafeb938c310cff1de5ff924a1c794325a
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A2_(IPAN/IN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SCG5 LRRN3 SLC18A3 ASTN1 DCLK1	7.84e-05	197	99	5	27c044833e471a312a572e0b1c83e4bc8a36e896
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-tRG-25\|World / Primary Cells by Cluster	LRIG3 MAST4 ATF3 NOTCH2 FOXJ1	7.84e-05	197	99	5	9d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTSL1 CIT CAPN8 MAST4 MUC5AC	8.03e-05	198	99	5	af399569c718f5fd971d73a7926768c9311002a3
ToppCell	medial-2-Epithelial-Mucous\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SGPP2 CAPN8 FCGBP KRTCAP3 MUC5AC	8.22e-05	199	99	5	4737250b7ffa7cc19eb6b057d35d78f13b1afe66
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX18 KL MAST4 RFLNB NOTCH4	8.22e-05	199	99	5	b15304d3d3f6c254969b54a61bee3d9f368840b2
ToppCell	medial-Epithelial-Mucous\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SGPP2 CAPN8 FCGBP KRTCAP3 MUC5AC	8.22e-05	199	99	5	4385963ab25b5378e7964b984028c25b27e5794e
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-arteriolar_fibroblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SCG5 TRIL LRIG3 ASTN1 DCLK1	8.22e-05	199	99	5	95d95e9b7bd3933188998ae94986213eb0f1e5ea
ToppCell	distal-2-Epithelial-Mucous\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SGPP2 CAPN8 FCGBP KRTCAP3 MUC5AC	8.22e-05	199	99	5	c0275b5011c2bb08e873955afe2e213ec8070d0e
ToppCell	medial-Epithelial-Mucous-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SGPP2 CAPN8 FCGBP KRTCAP3 MUC5AC	8.22e-05	199	99	5	53198bcf5f2f012a3ed1600d95c0923d6976a099
ToppCell	10x3'2.3-week_12-13-Mesenchymal_fibro-stroma-arteriolar_fibroblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ADAMTSL1 TRIL LRIG3 DCLK1 GULP1	8.41e-05	200	99	5	fee22a6a6c7b93af204b5b56f2c34f1411500e18
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	CSMD2 MAST4 AJAP1 RFLNB MAST1	8.41e-05	200	99	5	5c7263c862093ad9dbc81d06b16b6f74e8a6b634
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FCGBP SMG9 METTL8 WDR62	1.97e-04	129	99	4	cbeeaa554da971ba2e4c4b82c85a1d070a45abb8
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Col15a1_Pde1a\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LAMA5 RGS12 ATF3 GULP1	2.27e-04	134	99	4	d63fff23040eada31bc35ba1e05b7c6a663e0037
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast-matrix_-_mature_3\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	KLF15 LRCH3 RIN1 LRRN3	2.48e-04	137	99	4	9bfdbc102cdd861996b3c4eac35b606be8af97eb
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	DCHS2 SGPP2 CFAP65 NEFH	2.99e-04	144	99	4	08005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCell	mild_COVID-19_(asymptomatic)-Treg\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	CHAC2 SGPP2 MAST4 KRTCAP3	3.07e-04	145	99	4	2d0903009e918500facfd017ff31f2cec1e76131
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SGPP2 CSMD2 RIN1 GAREM1	3.24e-04	147	99	4	8f725ff8fb4ced5db2643e80669d3f7945b820ab
ToppCell	MS-CD4-CD8_1\|MS / Condition, Cell_class and T cell subcluster	KCP GPR135 CSMD2 DCLK1	3.49e-04	150	99	4	7dc95c58b98d8c4c6c49fb1a03ec6ac24fb41f54
ToppCell	Enthrocyte\|World / shred on cell class and cell subclass (v4)	CHAC2 CSMD2 NEFH RNF10	3.77e-04	153	99	4	654265f3c14344071b2af7ca05cbdbb17ce2c5d3
ToppCell	Enthrocyte\|World / shred on cell class and cell subclass (v4)	CHAC2 CSMD2 NEFH RNF10	3.77e-04	153	99	4	105b91f5277d145f7717307d7eb9b7d8e8e23576
ToppCell	367C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	NLRP6 ADAD2 LRIG3 ATF3	3.96e-04	155	99	4	335cd798afbaa0a3a3e1dc558a81cfa32da48983
ToppCell	367C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	NLRP6 ADAD2 LRIG3 ATF3	4.05e-04	156	99	4	fc8b8aef29d6d1c0f0c1d08280d8aaff8d30535e
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	SZT2 MLXIPL NOTCH2 GAREM1	4.67e-04	162	99	4	810881210e015c788814e4fe8d7a24c929cf2621
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SOX18 ZNF469 RFLNB NOTCH4	4.67e-04	162	99	4	c399b9e4854916a59f5cae2d8dbf19660f8759be
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SOX18 ZNF469 RFLNB NOTCH4	4.67e-04	162	99	4	a291248b693c771845174393934a782f1d8bd7ce
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADAMTSL1 CIT CAPN8 MAST4	4.67e-04	162	99	4	5c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Htr2c\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LAMA5 CIT RGS12 ATF3	5.01e-04	165	99	4	c6b23013d77fa9aa967b76e451c8e42b0a657c30
ToppCell	368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)\|368C / Donor, Lineage, Cell class and subclass (all cells)	DCHS2 LAMA5 KL NOTCH4	5.12e-04	166	99	4	30a991fc3275b571d53bd0976df4789e5d40b01d
ToppCell	368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	DCHS2 LAMA5 KL NOTCH4	5.12e-04	166	99	4	76b4cd32698900797ec009f17e50ea7ae36b85f4
ToppCell	Adult-Epithelial-lung_goblet_cell-D122\|Adult / Lineage, Cell type, age group and donor	ADAMTSL1 CAPN8 FCGBP MUC5AC	5.24e-04	167	99	4	6efbb2ef6adc8da5dd67210969f825f5cc8ed022
ToppCell	TCGA-Pancreas\|World / Sample_Type by Project: Shred V9	PNLIP PNLIPRP2 CAPN8 MUC5AC	5.36e-04	168	99	4	279d5fcf9bd3f56ab560e37eed6fb3bd57dd93de
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX18 TRIL RFLNB NOTCH4	5.36e-04	168	99	4	37249f38f8f04ec5743097259de67b106ca2b02f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCHS2 ADAMTSL1 PTPRU KL	5.36e-04	168	99	4	7abaddbcc55e44653d54aa15464266aa6bd5c9d2
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PNLIP PNLIPRP2 TRIL FCGBP	5.48e-04	169	99	4	d18b823836ca6fba79a2d2f10cb9966fa2623af2
ToppCell	3'_v3-Lung-Myeloid_Mac-Intestinal_macrophages\|Lung / Manually curated celltypes from each tissue	TRIL FCGBP ATF3 GULP1	5.48e-04	169	99	4	241644823e6f949aaf4c671d4579721d7ef6b0e5
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PNLIP PNLIPRP2 TRIL FCGBP	5.48e-04	169	99	4	befb9b1618ea30fbf8983bcc493853da53b809c3
ToppCell	facs-Lung-nan-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR135 PTPRU RIN1 RFLNB	5.60e-04	170	99	4	8e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LAMA5 CIT CAPN8 MAST4	5.60e-04	170	99	4	a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RGS12 LRIG3 FCGBP ZNRF3	5.60e-04	170	99	4	5d5f208682be21ed58320f5fc083a7898f8712da
Disease	obsolete_red blood cell distribution width	SCG5 SHBG FTCDNL1 CIT MLXIPL MAST4 GAREM2 ZNRF3 ZNF516 RNF10 SMG9 MAST1 USP4 GRIN3B	1.29e-04	1347	97	14	EFO_0005192
Disease	Hodgkins lymphoma	TM7SF3 ZNF526 FCGBP SLC18A3	1.58e-04	82	97	4	EFO_0000183
Disease	obesity (implicated_via_orthology)	DCHS2 PNLIP CAPN8 NOTCH2 NOTCH4	7.34e-04	215	97	5	DOID:9970 (implicated_via_orthology)
Disease	hemoglobin A1 measurement	SHBG MLXIPL KL USP4 NOTCH2 ARAP1 GULP1	1.66e-03	520	97	7	EFO_0007629
Disease	HbA1c measurement	SHBG NLRP6 MLXIPL KL MAST1 USP4 NOTCH2 ARAP1	1.74e-03	675	97	8	EFO_0004541
Disease	Primary microcephaly	CIT WDR62	2.37e-03	22	97	2	C0431350
Disease	Autosomal Recessive Primary Microcephaly	CIT WDR62	2.37e-03	22	97	2	C3711387

Protein segments in the cluster

Peptide	Gene	Start	Entry
EFPGCHSPAPPENFG	DCANP1	36	Q8TF63
LLFREDQPPGPCFPF	ADAD2	131	Q8NCV1
DQPPGPCFPFSVSAE	ADAD2	136	Q8NCV1
CGPFPNPLEEGISFD	CABCOCO1	106	Q8IVU9
ELPQCFPVFCGDPGV	CSMD2	3061	Q7Z408
VDLPACEALGPGPEF	AJAP1	36	Q9UKB5
SVPELPTIPEGGCFD	CCNG2	286	Q16589
DFSEDQGYPDPPNPC	SCG5	106	P05408
DSGVLFKDPEFPACP	CAPN8	41	A6NHC0
PCQLSPSGFSGEELP	CIT	401	O14578
TAFGADGLPTCAPLP	ASTN1	1016	O14525
DLAPPASPGIFAEAC	R3HDM4	96	Q96D70
GLEFGKLPFGACEDP	RAB3GAP1	261	Q15042
VCGFTPEPAPGAAFL	CAPN15	66	O75808
EGIGADPEPPVAAFC	ARHGEF17	646	Q96PE2
DPEPPVAAFCGLGTT	ARHGEF17	651	Q96PE2
DDNCSGPLFPPPELA	MFRP	451	Q9BY79
APELYGACAPELPGE	RB1CC1	1406	Q8TDY2
PPGFTGPVCQIDIDD	NOTCH2	521	Q04721
PAPIPNGFCADFSPE	LPCAT1	506	Q8NF37
HPLLDGVDGECPFPS	LRCH3	521	Q96II8
GLDPAEPCFQGTPEL	PNLIP	191	P16233
VSPDGFVCDDFPKPQ	LRIG3	486	Q6UXM1
LTPSDPGEFCVDVGP	LMAN1L	206	Q9HAT1
VEVDFGACPGPEAPN	CFAP65	656	Q6ZU64
LCGFPPFRGSGDDQE	DCLK1	581	O15075
GSPFTFCVVDEPPGI	DSG4	521	Q86SJ6
GPCSGEIPEFNPDET	ADAMTSL1	581	Q8N6G6
PGPGCVFLSQEISFP	HTD2	101	P86397
GFPVCPKLSLEFGDP	PDE12	176	Q6L8Q7
PAPFDFDGCELLASP	GAREM1	666	Q9H706
PDTCPEVGFFDVLGN	ACBD3	126	Q9H3P7
CELPGGPPSDAFVVS	MUC5AC	5406	P98088
TPCILGPLEAGLFFP	LAMA5	3511	O15230
LVGCVPFFGDTPEEL	MAST1	581	Q9Y2H9
PGGQDCFPVPLTFEA	PTPRU	641	Q92729
DINDNRPFFPQCLPG	DCHS2	1286	Q6V1P9
DGLLFPRPCQGQDPS	PGR	56	P06401
LEGEECRIGFGPIPF	NEFH	406	P12036
CLPAAFLDLFTPPGG	GPR135	156	Q8IZ08
PCTPEQQESFGGPDA	FCGBP	2251	Q9Y6R7
DCPVPTPGFGNVEEI	FUT11	426	Q495W5
AEPFDPFNCGAADFP	GULP1	256	Q9UBP9
PFNCGAADFPPDIQS	GULP1	261	Q9UBP9
SGCLPPEPLFEAGDA	FOXJ1	391	Q92949
PCLSPPGSLVFEDFA	ATF3	21	P18847
FLVGCVPFFGDTPEE	MAST4	776	O15021
NGFPGPETLERFCPE	KL	951	Q9UEF7
KGEHFCLPEFPLGDP	KLF15	116	Q9UIH9
GDVCLPPGHPDAINF	HBP1	331	O60381
PGCSVFLFGEADLPE	FTCDNL1	81	E5RQL4
SGKAFCFLPLPPGEE	SACS	441	Q9NZJ4
DVCDDGLPYPFPDGI	METTL8	256	Q9H825
ALGGPEAAPCTDPFE	NLRP6	286	P59044
VPLDEGPGHTDCPFD	KRTCAP3	141	Q53RY4
ITGLDPAGPCFQDEP	PNLIPRP2	191	P54317
FPSTPLVTEQDGCGP	NUTM2B	181	A6NNL0
PFVFARDPDEDGQCP	GRIN3B	426	O60391
PVLEPFDPFELGQGS	GAREM2	696	Q75VX8
PEGVPFAEGSCPAND	SZT2	1016	Q5T011
ALCFFNPLFPGDLGP	RIN1	221	Q13671
PRSPPGPFDACEDDY	SLC18A3	511	Q16572
PDSLFCVDPPEFQGQ	LRRN3	391	Q9H3W5
CPLSFGEGVEFDPLP	RFLNB	86	Q8N5W9
YEPGESFQPGADPCE	KCP	1026	Q6ZWJ8
LLPASFPCIFGPGEN	OPLAH	401	O14841
CLPTPPSNIFGGLDE	POU4F2	91	Q12837
VFLPSEAPCPDPDGF	NBEAL2	1331	Q6ZNJ1
CNVFPGLPPDFLDSE	SMG9	411	Q9H0W8
SCDVESNPGIFLPPG	SHBG	216	P04278
PGADIDPTQITFPGC	SETMAR	61	Q53H47
GDPQGSEEKLSCFPP	SHROOM2	256	Q13796
PVCGFVTPLQGPEAD	MLXIPL	141	Q9NP71
PGFIGPDCEVNPDNC	NOTCH4	266	Q99466
CGLFPAPDEGPRENG	SGPP2	21	Q8IWX5
AGINCFSGDPEAPTP	ARAP1	686	Q96P48
GTCDNPDYLGPAPLE	CHAC2	111	Q8WUX2
LFCGDPGPEIEPFSL	CLUHP3	51	Q96NS8
LDRFTEPPAFGPVCD	PPP3CC	211	P48454
PELSPGEFPCEVCGQ	ZNF516	241	Q92618
PDEFGSSPLEPGACN	USP4	636	Q13107
CDPVPNEFPGAFPSN	ZNF804B	1066	A4D1E1
PVCSFDPEGLIFAAG	WDR82	151	Q6UXN9
FCPDPEGSPPFEAAH	RGS12	476	O14924
PSFCVGSLEEDSPFP	RNF10	696	Q8N5U6
GLPPLVSDPCDFNKF	TRIL	571	Q7L0X0
GPEGPGEPRQFICNE	ZNF775	271	Q96BV0
PNFCEPNPETGSFGT	WNT3	281	P56703
SCSFRPNGFDDNDPP	USP38	1006	Q8NB14
CDPAGFNRDPLGVPV	ZNF469	1326	Q96JG9
FPGCAGPTEDELSLP	WDR62	1026	O43379
RCPELPPFSLFGDLE	ZNF598	121	Q86UK7
CQGYDPPEGFIPDLS	FTSJ1	196	Q9UET6
GCPPEEAGAVRANFP	ZNRF3	891	Q9ULT6
LEPELVPGAEGPFQC	ZNF526	96	Q8TF50
GEAAFFPPPAAPEDC	SOX18	226	P35713
AADEPPPDGCNAFVV	UGGT2	126	Q9NYU1
AVREFLCLDDPPGPF	SNX16	206	P57768
GPISFFPESGQPECL	ZNF512	311	Q96ME7
EPPPEGCNSFFSVHG	UGGT1	141	Q9NYU2
PGGCNLEFDLDIDPN	TM7SF3	136	Q9NS93
FPVQPPFAEGSDECL	NDC1	301	Q9BTX1