Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhigh-affinity IgG receptor activity

FCGR1A FCGR1BP

2.65e-062332GO:0019771
GeneOntologyMolecularFunctionleukotriene receptor binding

FCGR1A FCGR1BP

2.65e-062332GO:0031774
GeneOntologyMolecularFunctionIgG receptor activity

FCGR1A FCGR1BP

5.53e-057332GO:0019770
GeneOntologyMolecularFunctionIgG binding

FCGR1A FCGR1BP

1.44e-0411332GO:0019864
GeneOntologyMolecularFunctionimmunoglobulin receptor activity

FCGR1A FCGR1BP

2.38e-0414332GO:0019763
GeneOntologyMolecularFunctionimmunoglobulin binding

FCGR1A FCGR1BP

1.61e-0336332GO:0019865
GeneOntologyBiologicalProcesstype III hypersensitivity

FCGR1A FCGR1BP

2.63e-055342GO:0001802
GeneOntologyBiologicalProcessregulation of type III hypersensitivity

FCGR1A FCGR1BP

2.63e-055342GO:0001803
GeneOntologyBiologicalProcesspositive regulation of type III hypersensitivity

FCGR1A FCGR1BP

2.63e-055342GO:0001805
GeneOntologyBiologicalProcessdetermination of adult lifespan

CFH SCN2A HTT

9.58e-0554343GO:0008340
GeneOntologyBiologicalProcesspositive regulation of type IIa hypersensitivity

FCGR1A FCGR1BP

1.18e-0410342GO:0001798
GeneOntologyBiologicalProcesspositive regulation of type II hypersensitivity

FCGR1A FCGR1BP

1.18e-0410342GO:0002894
GeneOntologyBiologicalProcessregulation of type IIa hypersensitivity

FCGR1A FCGR1BP

1.44e-0411342GO:0001796
GeneOntologyBiologicalProcessregulation of type II hypersensitivity

FCGR1A FCGR1BP

1.44e-0411342GO:0002892
GeneOntologyBiologicalProcessantibody-dependent cellular cytotoxicity

FCGR1A FCGR1BP

2.03e-0413342GO:0001788
GeneOntologyBiologicalProcesstype IIa hypersensitivity

FCGR1A FCGR1BP

2.73e-0415342GO:0001794
GeneOntologyBiologicalProcesspositive regulation of hypersensitivity

FCGR1A FCGR1BP

2.73e-0415342GO:0002885
GeneOntologyBiologicalProcesstype II hypersensitivity

FCGR1A FCGR1BP

2.73e-0415342GO:0002445
GeneOntologyBiologicalProcesspositive regulation of acute inflammatory response to antigenic stimulus

FCGR1A FCGR1BP

3.53e-0417342GO:0002866
GeneOntologyBiologicalProcesspositive regulation of phagocytosis, engulfment

FCGR1A FCGR1BP

3.97e-0418342GO:0060100
GeneOntologyBiologicalProcesspositive regulation of membrane invagination

FCGR1A FCGR1BP

3.97e-0418342GO:1905155
GeneOntologyBiologicalProcessnegative regulation of muscle tissue development

USP2 HDAC7

3.97e-0418342GO:1901862
GeneOntologyBiologicalProcessantigen processing and presentation of exogenous peptide antigen via MHC class I

FCGR1A FCGR1BP

3.97e-0418342GO:0042590
GeneOntologyBiologicalProcessregulation of hypersensitivity

FCGR1A FCGR1BP

4.43e-0419342GO:0002883
GeneOntologyBiologicalProcessmaintenance of location

TMED2 LTBP1 CAV1 CD19 HTT

4.47e-04396345GO:0051235
GeneOntologyBiologicalProcessimmunoglobulin mediated immune response

CFH FCGR1A FCGR1BP CD19

5.82e-04235344GO:0016064
GeneOntologyBiologicalProcessprotein localization to cell periphery

TMED2 PPIL2 CAV1 C1QL3 WDR72

5.97e-04422345GO:1990778
GeneOntologyBiologicalProcesspositive regulation of inflammatory response to antigenic stimulus

FCGR1A FCGR1BP

6.53e-0423342GO:0002863
GeneOntologyBiologicalProcessB cell mediated immunity

CFH FCGR1A FCGR1BP CD19

6.70e-04244344GO:0019724
GeneOntologyBiologicalProcessblood vessel development

CFH PCSK5 TMED2 LTBP1 CAV1 HDAC7 TIPARP

6.80e-04929347GO:0001568
GeneOntologyBiologicalProcessregulation of phagocytosis, engulfment

FCGR1A FCGR1BP

7.12e-0424342GO:0060099
GeneOntologyBiologicalProcesspositive regulation of calcium ion transmembrane transport

CAV1 CD19 HTT

7.62e-04109343GO:1904427
GeneOntologyBiologicalProcessregulation of membrane invagination

FCGR1A FCGR1BP

7.73e-0425342GO:1905153
GeneOntologyBiologicalProcesshypersensitivity

FCGR1A FCGR1BP

7.73e-0425342GO:0002524
GeneOntologyBiologicalProcessmaintenance of protein location

TMED2 LTBP1 CAV1

8.25e-04112343GO:0045185
GeneOntologyBiologicalProcessmaintenance of location in cell

TMED2 CAV1 CD19 HTT

8.38e-04259344GO:0051651
GeneOntologyBiologicalProcessvasculature development

CFH PCSK5 TMED2 LTBP1 CAV1 HDAC7 TIPARP

8.73e-04969347GO:0001944
GeneOntologyBiologicalProcessregulation of acute inflammatory response to antigenic stimulus

FCGR1A FCGR1BP

9.02e-0427342GO:0002864
GeneOntologyBiologicalProcessprotein localization to membrane

ETV5 TMED2 PPIL2 CAV1 C1QL3 WDR72

9.26e-04705346GO:0072657
GeneOntologyBiologicalProcessvasculogenesis

CAV1 HDAC7 TIPARP

9.60e-04118343GO:0001570
DomainZnf_CCCH

TRMT1 ZC3H12B TIPARP

1.73e-0458353IPR000571
DomainZF_C3H1

TRMT1 ZC3H12B TIPARP

1.73e-0458353PS50103
DomainMAM_1

ZAN MAMDC2

4.03e-0416352PS00740
DomainMAM

ZAN MAMDC2

4.56e-0417352SM00137
DomainMAM

ZAN MAMDC2

5.12e-0418352PF00629
DomainMAM_dom

ZAN MAMDC2

5.12e-0418352IPR000998
DomainMAM_2

ZAN MAMDC2

5.12e-0418352PS50060
DomainEGF

PCSK5 LTBP1 ZAN ATRAID

9.42e-04235354SM00181
DomainEGF-like_dom

PCSK5 LTBP1 ZAN ATRAID

1.17e-03249354IPR000742
Domainzf-CCCH

TRMT1 TIPARP

3.80e-0349352PF00642
DomainUSP_CS

USP2 USP32

6.79e-0366352IPR018200
DomainUSP_1

USP2 USP32

7.61e-0370352PS00972
DomainIG

FCGR1A FCGR1BP CD19 HAPLN1

7.67e-03421354SM00409
DomainIg_sub

FCGR1A FCGR1BP CD19 HAPLN1

7.67e-03421354IPR003599
DomainUCH

USP2 USP32

7.82e-0371352PF00443
DomainUSP_2

USP2 USP32

7.82e-0371352PS00973
DomainUSP_3

USP2 USP32

8.03e-0372352PS50235
DomainUSP_dom

USP2 USP32

8.03e-0372352IPR028889
DomainPeptidase_C19_UCH

USP2 USP32

8.03e-0372352IPR001394
DomainIg_2

FCGR1A FCGR1BP

8.25e-0373352PF13895
DomainEGF_3

LTBP1 ZAN ATRAID

9.57e-03235353PS50026
DomainEGF_1

LTBP1 ZAN ATRAID

1.19e-02255353PS00022
DomainEGF-like_CS

LTBP1 ZAN ATRAID

1.27e-02261353IPR013032
DomainIG_LIKE

FCGR1A FCGR1BP CD19 HAPLN1

1.30e-02491354PS50835
DomainEGF_2

LTBP1 ZAN ATRAID

1.32e-02265353PS01186
DomainIg-like_dom

FCGR1A FCGR1BP CD19 HAPLN1

1.41e-02503354IPR007110
Pubmed

Single Nucleotide Polymorphisms of the High Affinity IgG Receptor FcγRI Reduce Immune Complex Binding and Downstream Effector Functions.

FCGR1A FCGR1BP

9.84e-07235228814603
Pubmed

Features and protective efficacy of human mAbs targeting Mycobacterium tuberculosis arabinomannan.

FCGR1A FCGR1BP

9.84e-07235237733444
Pubmed

Modulating IgG effector function by Fc glycan engineering.

FCGR1A FCGR1BP

9.84e-07235228289219
Pubmed

Amelioration of Lupus Serum-Induced Skin Inflammation in CD64-Deficient Mice.

FCGR1A FCGR1BP

9.84e-07235235273604
Pubmed

IgG3-mediated enhancement of the antibody response is normal in Fc gammaRI-deficient mice.

FCGR1A FCGR1BP

9.84e-07235216305642
Pubmed

Congenic mapping of the insulin-dependent diabetes (Idd) gene, Idd10, localizes two genes mediating the Idd10 effect and eliminates the candidate Fcgr1.

FCGR1A FCGR1BP

9.84e-0723529257847
Pubmed

Fcγ receptor I alpha chain (CD64) expression in macrophages is critical for the onset of meningitis by Escherichia coli K1.

FCGR1A FCGR1BP

9.84e-07235221124939
Pubmed

Macrophages eliminate circulating tumor cells after monoclonal antibody therapy.

FCGR1A FCGR1BP

9.84e-07235224430180
Pubmed

Expression of modified FcγRI enables myeloid cells to elicit robust tumor-specific cytotoxicity.

FCGR1A FCGR1BP

9.84e-07235238885133
Pubmed

Novel Fc gamma receptor I family gene products in human mononuclear cells.

FCGR1A FCGR1BP

9.84e-0723521430234
Pubmed

The FcRgamma chain is not essential for induction of experimental allergic encephalomyelitis (EAE) or anti-myelin antibody-mediated exacerbation of EAE.

FCGR1A FCGR1BP

9.84e-07235215835266
Pubmed

Extracellular mutations of non-obese diabetic mouse FcgammaRI modify surface expression and ligand binding.

FCGR1A FCGR1BP

9.84e-0723528663283
Pubmed

The interaction of N-glycans in Fcγ receptor I α-chain with Escherichia coli K1 outer membrane protein A for entry into macrophages: experimental and computational analysis.

FCGR1A FCGR1BP

9.84e-07235225231998
Pubmed

Lentivirus-mediated knockdown of FcγRI (CD64) attenuated lupus nephritis via inhibition of NF-κB regulating NLRP3 inflammasome activation in MRL/lpr mice.

FCGR1A FCGR1BP

9.84e-07235230190171
Pubmed

Neurological abnormalities in caveolin-1 knock out mice.

CAV1 HTT

9.84e-07235216750274
Pubmed

Molecular cloning and expression of the mouse high affinity Fc receptor for IgG.

FCGR1A FCGR1BP

9.84e-0723522136886
Pubmed

Gene organization of the human high affinity receptor for IgG, Fc gamma RI (CD64). Characterization and evidence for a second gene.

FCGR1A FCGR1BP

9.84e-0723521830050
Pubmed

FcRγ deficiency improves survival in experimental sepsis by down-regulating TLR4 signaling pathway.

FCGR1A FCGR1BP

9.84e-07235230552619
Pubmed

Sensory Neuron Expressed FcγRI Mediates Postinflammatory Arthritis Pain in Female Mice.

FCGR1A FCGR1BP

9.84e-07235235833115
Pubmed

Differential gene expression modulated by the cytoplasmic domain of Fc gamma RIa (CD64) alpha-chain.

FCGR1A FCGR1BP

9.84e-07235215528358
Pubmed

Functional characteristics of the high affinity IgG receptor, FcγRI.

FCGR1A FCGR1BP

9.84e-07235221325219
Pubmed

Fc receptors and the common gamma-chain in experimental autoimmune encephalomyelitis.

FCGR1A FCGR1BP

9.84e-07235214991835
Pubmed

Definition of interferon gamma-response elements in a novel human Fc gamma receptor gene (Fc gamma RIb) and characterization of the gene structure.

FCGR1A FCGR1BP

9.84e-0723521402657
Pubmed

FcR gamma-chain is essential for both surface expression and function of human Fc gamma RI (CD64) in vivo.

FCGR1A FCGR1BP

9.84e-0723528611682
Pubmed

Loss of caveolin-1 expression in knock-in mouse model of Huntington's disease suppresses pathophysiology in vivo.

CAV1 HTT

9.84e-07235224021477
Pubmed

Direct targeting of genetically modified tumour cells to Fc gammaRI triggers potent tumour cytotoxicity.

FCGR1A FCGR1BP

9.84e-07235216409296
Pubmed

Mouse FcgammaRI: identification and functional characterization of five new alleles.

FCGR1A FCGR1BP

9.84e-07235210752630
Pubmed

Fcγ Receptor Type I (CD64)-Mediated Impairment of the Capacity of Dendritic Cells to Activate Specific CD8 T Cells by IgG-opsonized Friend Virus.

FCGR1A FCGR1BP

9.84e-07235230744065
Pubmed

Serum anti-Fcgamma receptor autoantibodies in patients with alopecia areata.

FCGR1A FCGR1BP

9.84e-07235217124586
Pubmed

Neuronal FcγRI mediates acute and chronic joint pain.

FCGR1A FCGR1BP

9.84e-07235231211699
Pubmed

Linkage on chromosome 3 of autoimmune diabetes and defective Fc receptor for IgG in NOD mice.

FCGR1A FCGR1BP

9.84e-0723528480181
Pubmed

Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.

FCGR1A FCGR1BP

9.84e-07235229576375
Pubmed

Amelioration of crescentic glomerulonephritis by RhoA kinase inhibitor, Fasudil, through podocyte protection and prevention of leukocyte migration.

FCGR1A FCGR1BP

9.84e-07235218245810
Pubmed

Reconstitution of allogeneic hemopoietic stem cells: the essential role of FcR gamma and the TCR beta-chain-FCp33 complex.

FCGR1A FCGR1BP

9.84e-07235216849450
Pubmed

Biochemical characterization of murine Fc gamma RI.

FCGR1A FCGR1BP

9.84e-0723528478020
Pubmed

FcγR-binding affinity of monoclonal murine IgG1s carrying different N-linked Fc oligosaccharides.

FCGR1A FCGR1BP

9.84e-07235231554601
Pubmed

CD64 plays a key role in diabetic wound healing.

FCGR1A FCGR1BP

9.84e-07235238524127
Pubmed

Developmentally ordered appearance of a functional Fc gamma receptor on TCR V gamma 3 thymocytes. Evidence for stimulation-induced expression.

FCGR1A FCGR1BP

9.84e-0723528077658
Pubmed

The involvement of FcR mechanisms in antibody-mediated rejection.

FCGR1A FCGR1BP

9.84e-07235218049118
Pubmed

Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria.

FCGR1A FCGR1BP

2.95e-06335216841095
Pubmed

Nephrotoxic nephritis is mediated by Fcgamma receptors on circulating leukocytes and not intrinsic renal cells.

FCGR1A FCGR1BP

2.95e-06335212427132
Pubmed

MicroRNA-127 inhibits lung inflammation by targeting IgG Fcγ receptor I.

FCGR1A FCGR1BP

2.95e-06335222287715
Pubmed

Tpl2 kinase regulates FcγR signaling and immune thrombocytopenia in mice.

FCGR1A FCGR1BP

2.95e-06335223898046
Pubmed

Serine phosphorylation of FcγRI cytoplasmic domain directs lipid raft localization and interaction with protein 4.1G.

FCGR1A FCGR1BP

2.95e-06335222003208
Pubmed

Unique monoclonal antibodies define expression of Fc gamma RI on macrophages and mast cell lines and demonstrate heterogeneity among subcutaneous and other dendritic cells.

FCGR1A FCGR1BP

2.95e-06335212594281
Pubmed

Development of proteoglycan-induced arthritis is critically dependent on Fcgamma receptor type III expression.

FCGR1A FCGR1BP

2.95e-06335215880819
Pubmed

A new mouse expressing human Fcγ receptors to better predict therapeutic efficacy of human anti-cancer antibodies.

FCGR1A FCGR1BP

2.95e-06335228924242
Pubmed

Fcgamma receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalization.

FCGR1A FCGR1BP

2.95e-0633529892619
Pubmed

Residual LCMV antigen in transiently CD4+ T cell-depleted mice induces high levels of virus-specific antibodies but only limited B-cell memory.

FCGR1A FCGR1BP

2.95e-06335230636035
Pubmed

Cutting Edge: Drebrin-Regulated Actin Dynamics Regulate IgE-Dependent Mast Cell Activation and Allergic Responses.

FCGR1A FCGR1BP

2.95e-06335226056254
Pubmed

The essential role of complement in antibody-mediated resistance to Salmonella.

FCGR1A FCGR1BP

2.95e-06335230179254
Pubmed

The three genes of the human FCGR1 gene family encoding Fc gamma RI flank the centromere of chromosome 1 at 1p12 and 1q21.

FCGR1A FCGR1BP

2.95e-0633528697799
Pubmed

Transcriptional and post-transcriptional regulation of IκB-ζ upon engagement of the BCR, TLRs and FcγR.

FCGR1A FCGR1BP

2.95e-06335223728777
Pubmed

FcγRI mediates serum amyloid P inhibition of fibrocyte differentiation.

FCGR1A FCGR1BP

2.95e-06335222493081
Pubmed

FcgammaR-induced production of superoxide and inflammatory cytokines is differentially regulated by SHIP through its influence on PI3K and/or Ras/Erk pathways.

FCGR1A FCGR1BP

2.95e-06335216543474
Pubmed

Escherichia coli K1 induces pterin production for enhanced expression of Fcγ receptor I to invade RAW 264.7 macrophages.

FCGR1A FCGR1BP

2.95e-06335224161960
Pubmed

Both Fcgamma receptor I and Fcgamma receptor III mediate disease in accelerated nephrotoxic nephritis.

FCGR1A FCGR1BP

2.95e-06335212707052
Pubmed

FcgammaRI ligation leads to a complex with BLT1 in lipid rafts that enhances rat lung macrophage antimicrobial functions.

FCGR1A FCGR1BP

2.95e-06335219657115
Pubmed

Fc-optimized antibodies elicit CD8 immunity to viral respiratory infection.

FCGR1A FCGR1BP

2.95e-06335233032297
Pubmed

Localization of FCGR1 encoding Fcgamma receptor class I in primates: molecular evidence for two pericentric inversions during the evolution of human chromosome 1.

FCGR1A FCGR1BP

2.95e-0633529763663
Pubmed

C1q-Dependent Dendritic Cell Cross-Presentation of In Vivo-Formed Antigen-Antibody Complexes.

FCGR1A FCGR1BP

2.95e-06335228432146
Pubmed

Toxicity of an Fc-engineered anti-CD40 antibody is abrogated by intratumoral injection and results in durable antitumor immunity.

FCGR1A FCGR1BP

2.95e-06335230297432
Pubmed

FcgammaRI up-regulation induced by local adenoviral-mediated interferon-gamma production aggravates chondrocyte death during immune complex-mediated arthritis.

FCGR1A FCGR1BP

2.95e-06335212875993
Pubmed

Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line.

FCGR1A FCGR1BP CD19

3.72e-063035327729526
Pubmed

Identification of the mouse IgG3 receptor: implications for antibody effector function at the interface between innate and adaptive immunity.

FCGR1A FCGR1BP

5.90e-0643529551950
Pubmed

C-reactive protein-mediated suppression of nephrotoxic nephritis: role of macrophages, complement, and Fcgamma receptors.

FCGR1A FCGR1BP

5.90e-06435217182593
Pubmed

Signaling through mutants of the IgA receptor CD89 and consequences for Fc receptor gamma-chain interaction.

FCGR1A FCGR1BP

5.90e-06435216517729
Pubmed

Unveiling skin macrophage dynamics explains both tattoo persistence and strenuous removal.

FCGR1A FCGR1BP

5.90e-06435229511065
Pubmed

Universal vaccine based on ectodomain of matrix protein 2 of influenza A: Fc receptors and alveolar macrophages mediate protection.

FCGR1A FCGR1BP

5.90e-06435221169548
Pubmed

Evidence for Cd101 but not Fcgr1 as candidate for type 1 diabetes locus, Idd10.

FCGR1A FCGR1BP

5.90e-06435215850792
Pubmed

Human immunoglobulin G hinge regulates agonistic anti-CD40 immunostimulatory and antitumour activities through biophysical flexibility.

FCGR1A FCGR1BP

5.90e-06435231562320
Pubmed

Fc receptor regulation of protective immunity against Chlamydia trachomatis.

FCGR1A FCGR1BP

5.90e-06435211872097
Pubmed

Abolition of anti-glomerular basement membrane antibody-mediated glomerulonephritis in FcRgamma-deficient mice.

FCGR1A FCGR1BP

5.90e-06435210760808
Pubmed

Adenovirus-mediated human immunodeficiency virus-1 Nef expression in human monocytes/macrophages and effect of Nef on downmodulation of Fcgamma receptors and expression of monokines.

FCGR1A FCGR1BP

5.90e-0643529490697
Pubmed

Glycoprotein VI-dependent and -independent pathways of thrombus formation in vivo.

FCGR1A FCGR1BP

5.90e-06435216455953
Pubmed

Three genes for the human high affinity Fc receptor for IgG (Fc gamma RI) encode four distinct transcription products.

FCGR1A FCGR1BP

5.90e-0643521379234
Pubmed

A critical role for Syk protein tyrosine kinase in Fc receptor-mediated antigen presentation and induction of dendritic cell maturation.

FCGR1A FCGR1BP

5.90e-06435212517949
Pubmed

The high-affinity IgG receptor, FcgammaRI, plays a central role in antibody therapy of experimental melanoma.

FCGR1A FCGR1BP

5.90e-06435216452176
Pubmed

The mouse Fc receptor for IgG (Ly-17): molecular cloning and specificity.

FCGR1A FCGR1BP

5.90e-0643522957319
Pubmed

Mouse immune thrombocytopenia is associated with Th1 bias and expression of activating Fcγ receptors.

FCGR1A FCGR1BP

5.90e-06435228028748
Pubmed

The serine/threonine kinase Akt Promotes Fc gamma receptor-mediated phagocytosis in murine macrophages through the activation of p70S6 kinase.

FCGR1A FCGR1BP

5.90e-06435215485887
Pubmed

Fc receptor-mediated antibody regulation of T cell immunity against intracellular pathogens.

FCGR1A FCGR1BP

5.90e-06435212898452
Pubmed

Markedly different pathogenicity of four immunoglobulin G isotype-switch variants of an antierythrocyte autoantibody is based on their capacity to interact in vivo with the low-affinity Fcgamma receptor III.

FCGR1A FCGR1BP

5.90e-06435210770797
Pubmed

The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen.

FCGR1A FCGR1BP

5.90e-0643529171347
Pubmed

Fcgamma receptor cross-linking stimulates cell proliferation of macrophages via the ERK pathway.

FCGR1A FCGR1BP

5.90e-06435219996316
Pubmed

Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease.

FCGR1A FCGR1BP

5.90e-06435212705859
Pubmed

Transcription of the caveolin-1 gene is differentially regulated in lung type I epithelial and endothelial cell lines. A role for ETS proteins in epithelial cell expression.

ETV5 CAV1

5.90e-06435215138262
Pubmed

Coordinate expression of activating Fc gamma receptors I and III and inhibiting Fc gamma receptor type II in the determination of joint inflammation and cartilage destruction during immune complex-mediated arthritis.

FCGR1A FCGR1BP

5.90e-06435212528127
Pubmed

Dynamic macrophage "probing" is required for the efficient capture of phagocytic targets.

FCGR1A FCGR1BP

5.90e-06435221135140
Pubmed

Immune complex-loaded dendritic cells are superior to soluble immune complexes as antitumor vaccine.

FCGR1A FCGR1BP

5.90e-06435216585547
Pubmed

Fcgamma receptor deficiency confers protection against atherosclerosis in apolipoprotein E knockout mice.

FCGR1A FCGR1BP

9.82e-06535217053192
Pubmed

Fc gamma RIII and Fc gamma RIV are indispensable for acute glomerular inflammation induced by switch variant monoclonal antibodies.

FCGR1A FCGR1BP

9.82e-06535219050295
Pubmed

Efficient IgG-mediated suppression of primary antibody responses in Fcgamma receptor-deficient mice.

FCGR1A FCGR1BP

9.82e-06535210051626
Pubmed

C-reactive protein binding to murine leukocytes requires Fc gamma receptors.

FCGR1A FCGR1BP

9.82e-06535210640769
Pubmed

Phagocytosis in macrophages lacking Cbl reveals an unsuspected role for Fc gamma receptor signaling and actin assembly in target binding.

FCGR1A FCGR1BP

9.82e-06535219380812
Pubmed

Antibody isotype-specific engagement of Fcgamma receptors regulates B lymphocyte depletion during CD20 immunotherapy.

FCGR1A FCGR1BP

9.82e-06535216520392
Pubmed

Destructive arthritis in the absence of both FcgammaRI and FcgammaRIII.

FCGR1A FCGR1BP

9.82e-06535218354234
Pubmed

Role of FcRs in animal model of autoimmune bullous pemphigoid.

FCGR1A FCGR1BP

9.82e-06535216920981
Pubmed

Mouse model recapitulating human Fcγ receptor structural and functional diversity.

FCGR1A FCGR1BP

9.82e-06535222474370
Pubmed

Fc receptor biology.

FCGR1A FCGR1BP

9.82e-0653529143687
Cytoband19p13

CELF5 PLPP2

1.96e-042735219p13
Cytoband2p23.3

AGBL5 ATRAID

1.25e-03683522p23.3
CytobandEnsembl 112 genes in cytogenetic band chr2q24

UPP2 SCN2A

4.26e-03127352chr2q24
CytobandEnsembl 112 genes in cytogenetic band chr2p23

AGBL5 ATRAID

5.80e-03149352chr2p23
CytobandEnsembl 112 genes in cytogenetic band chr15q21

SPPL2A WDR72

8.09e-03177352chr15q21
CytobandEnsembl 112 genes in cytogenetic band chr9q21

PCSK5 MAMDC2

1.01e-02199352chr9q21
CytobandEnsembl 112 genes in cytogenetic band chrXp22

NHS KLHL34

1.56e-02250352chrXp22
CytobandEnsembl 112 genes in cytogenetic band chr19p13

TRMT1 CELF5 PLPP2

2.26e-02797353chr19p13
GeneFamilyImmunoglobulin like domain containing

FCGR1A FCGR1BP CD19

1.59e-03193223594
GeneFamilyUbiquitin specific peptidases

USP2 USP32

2.09e-0356222366
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK5 NHS USP2 GPT2 WDR72

3.36e-071863555784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFH NHS LTBP1 MAMDC2

6.04e-06152354621e9b33cd3bb1c7b7d0633069f286b203e3d9c0
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZC3H12B ZAN CD19 HDAC7

1.03e-05174354268be5e7d2a18b866770b7cdb966c3958c7e6534
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZC3H12B ZAN CD19 HDAC7

1.03e-051743544cdf2eedc28d88d18241ee390092426fdf849e79
ToppCell343B-Fibroblasts-Fibroblast-B_(Myofibroblast)|343B / Donor, Lineage, Cell class and subclass (all cells)

CFH ZC3H12B LTBP1 MAMDC2

1.10e-05177354e55d21d4d61a069b9bbe0e7595fbfb7cfbacfd87
ToppCellVE-plasma|VE / Condition, Cell_class and T cell subcluster

LTBP1 CAV1 CD19 HAPLN1

1.10e-051773540c1cc0834de55717cb4f69d020339060ce2c9a03
ToppCell343B-Fibroblasts-Fibroblast-B_(Myofibroblast)-|343B / Donor, Lineage, Cell class and subclass (all cells)

CFH ZC3H12B LTBP1 MAMDC2

1.10e-0517735443ba6f12c2fb32698a420bf799d46ac1b558f146
ToppCellVE-plasma-|VE / Condition, Cell_class and T cell subcluster

LTBP1 CAV1 CD19 HAPLN1

1.10e-051773543a3c94cf30012e2aa266bc4d7fe772e45fa90f6d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK5 GPT2 TIPARP WDR72

1.15e-0517935478fae47ec9bff4e0159a86a281e831d7f8ee925a
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFH NHS LTBP1 MAMDC2

1.18e-0518035401f2e5d96016823482f89ba503d007d4bd88eeac
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CFH PCSK5 DIPK1B CAV1

1.20e-051813540ba91575fe8851788cebc4cf5a6d76680bf586c5
ToppCellEndothelial-E|World / shred on cell class and cell subclass (v4)

PCSK5 LTBP1 CAV1 HAPLN1

1.28e-05184354b4c561924c508536fd2112e91e32176b95fdf63a
ToppCell(00)_Basal-(4)_1wkpi|(00)_Basal / shred by cell type and Timepoint

PCSK5 USP2 CAV1 TIPARP

1.31e-05185354bf82ba905e5eee1c39a2731702071d3de10a78b8
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK5 NHS GPT2 WDR72

1.37e-051873543ae3b8de1a195d4d5057cf3c64fcdb5f48681ce5
ToppCell(5)_Epi_basal|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

CFH CAV1 PLPP2 WDR72

1.49e-051913546bda3d5a8a391d41bb4d65872492e6c094bcc4d4
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 CELF5 LTBP1 CAV1

1.49e-05191354b9ae5af426e7a1f2652a47700bb168371bd2dec6
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CFH NHS LTBP1 CAV1

1.52e-05192354fee99ca7e658963acf968aa724ef8c96cfc00a5d
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

CFH NHS LTBP1 MAMDC2

1.55e-05193354e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell343B-Endothelial_cells-Endothelial-B_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CFH PCSK5 DIPK1B LTBP1

1.58e-05194354582db7f7fa9aa08027ae18ed607945b5d1dc908a
ToppCell343B-Endothelial_cells-Endothelial-B_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CFH PCSK5 DIPK1B LTBP1

1.58e-05194354bda89111386398a072b70e8153b2a762298a047a
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH LTBP1 MAMDC2 HAPLN1

1.65e-05196354e7bfd4fb400ae0c473131d0fa306c26be08a6d03
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH LTBP1 MAMDC2 HAPLN1

1.65e-0519635482fad623212d986a7fca3496faf3f8c8f5b83a11
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH LTBP1 MAMDC2 HAPLN1

1.65e-0519635485e5046f774537684e1443c0fc147d562b7068d0
ToppCellTracheal-10x3prime_v2-Stromal-Mesofibroblastic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CFH LTBP1 MAMDC2 USP32

1.68e-05197354d7cef7881abd807a679432766ced609a6efd1067
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH LTBP1 CAV1 MAMDC2

1.68e-0519735416758f181ef07c60aee63072e1da9572c5c85414
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CFH LTBP1 MAMDC2 HAPLN1

1.68e-0519735444673c38384453207871d3fd8e8ba9093cc06bc5
ToppCellTracheal-10x3prime_v2-Stromal-Mesofibroblastic-Mesothelia|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CFH LTBP1 MAMDC2 USP32

1.68e-0519735420a5958512bdb99daeb8f4d244df53e4f048f879
ToppCellFibroblasts-DKK3+_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

CFH LTBP1 CAV1 MAMDC2

1.71e-051983544f4632f26a2043c5e4ab89031b4229b5dca1bd48
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NHS USP2 LTBP1 KLHL34

1.71e-05198354f261a37dd07976548b897af86df1d1a0dc069889
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CFH PCSK5 LTBP1 CAV1

1.71e-051983545e781583908c4ee107d986904a646a7c6b8e3591
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFH LTBP1 MAMDC2 HAPLN1

1.71e-05198354300d7cc56207d77168390fa1ffcbcf76767b1b80
ToppCell3'-Broncho-tracheal-Mesenchymal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH LTBP1 CAV1 HAPLN1

1.71e-051983544961a3e9b953679648586afed04869ff36b81820
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRMT1 ETV5 FCGR1A MAMDC2

1.75e-05199354e1066e638af83ba5e89c7cabb8ad00b6bcdee5f4
ToppCellTracheal-10x3prime_v2-Stromal-Fibroblastic-Fibro_peribronchial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CFH LTBP1 MAMDC2 HAPLN1

1.75e-05199354e9009eee7f77b9c9917f8e0e723001d9e76eb553
ToppCelldistal-1-mesenchymal-Myofibroblast|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CFH LTBP1 MAMDC2 HAPLN1

1.75e-0519935458c36f5a30c6862b7f5587a0b9bc31da99e43dd5
ToppCellBiopsy_Other_PF-Mesenchymal-Fibroblasts|Biopsy_Other_PF / Sample group, Lineage and Cell type

CFH LTBP1 MAMDC2 SCN2A

1.78e-052003549996b6887cf2b1936e10a1aa396f09fd8da5f4c4
ToppCellParenchyma_COVID-19-Endothelial-TX-Artery|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

PCSK5 DIPK1B LTBP1 CAV1

1.78e-0520035434b279804475ea58fbb052b96f44128c082627a9
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Artery|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PCSK5 DIPK1B LTBP1 CAV1

1.78e-052003548552cc7a439449b30b59760c3e8667217b9852b5
ToppCellTracheal|World / Cell types per location group and 10X technology with lineage, and cell group designations

CFH NHS GPT2 PLPP2

1.78e-05200354682960e28542a3d6c119047cd0131941932cfdea
ToppCellBronchial-NucSeq-Stromal-Chondrocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CFH GPT2 TIPARP HAPLN1

1.78e-05200354b7b9441fa7ab0d43741a2ebd5ec1a48d537c6d47
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Artery-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PCSK5 DIPK1B LTBP1 CAV1

1.78e-0520035445c08f1befe78553bbadcc2fcffb6138306638f3
ToppCellBronchial-NucSeq-Stromal-Chondrocytic-Chondrocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CFH GPT2 TIPARP HAPLN1

1.78e-052003547c673ad0ea503ebd196579684d25d5f9e6a41030
ToppCellControl-B_naive-4|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PCSK5 TYW1 SCN2A

1.03e-0411635335d471c8dbf408d0be3837c428d9c2a73c805a6f
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Tmem182|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LTBP1 ZAN HAPLN1

1.25e-04124353690595d710b57b7cff8029a3bb06a8dd7e3c03c1
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

NHS PLPP2 UPP2

1.91e-0414335328e936c298a45f88d14f0146caf3d5a22d483cd5
ToppCellClub_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

CFH PLPP2 WDR72

2.07e-041473535a824c89e4d045af465d7333275f8191fb29b041
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LTBP1 ZAN HAPLN1

2.11e-041483535e738522d4ad35e08bc4ff8c41b7bea38ec6ef95
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LTBP1 ZAN HAPLN1

2.29e-041523538ff5a178a8f3550d89a003c0858820aab3773386
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZC3H12B SCN2A HAPLN1

2.42e-0415535377fdae85d36efb776db977eb424b32487ef222e4
ToppCell3'_v3-bone_marrow-Lymphocytic_B-Pro-B|bone_marrow / Manually curated celltypes from each tissue

KLHL34 CD19 HAPLN1

2.47e-04156353b093dbba6662e4fffc8aa577587b77f64ac44b56
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFH ZC3H12B MAMDC2

2.51e-04157353f147e24f2ece82e1c54750868954d09b3c461804
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFH ZC3H12B MAMDC2

2.56e-04158353e5636c0b608d68bd426a2b446ac508e4512e86a4
ToppCelldroplet-Kidney-nan-3m-Myeloid-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH FCGR1BP UPP2

2.61e-04159353bea6e96ba40ebfc1e38687bfa1c61fe227c5a84d
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFH NHS PLPP2

2.71e-041613532d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NHS ZC3H12B WDR72

2.71e-041613539f02b94e29e60d50e92eaa748ebf0c36d3671bb3
ToppCell368C-Fibroblasts-Fibroblast-E|368C / Donor, Lineage, Cell class and subclass (all cells)

CFH LTBP1 MAMDC2

2.76e-04162353e17632778a57c71d6005d3abca3a0443a92040e7
ToppCell368C-Fibroblasts-Fibroblast-E-|368C / Donor, Lineage, Cell class and subclass (all cells)

CFH LTBP1 MAMDC2

2.76e-04162353ac4a80fd72c9311ea2b3e574c6284bbce4f2756c
ToppCellTCGA-Colorectal-Solid_Tissue_Normal-Colon_normal_tissue-Colon_normal_tissue-6|TCGA-Colorectal / Sample_Type by Project: Shred V9

PCSK5 USP2 MAMDC2

2.76e-041623537f9385aa749bfb2fa9fee6939fe46d946bc21d31
ToppCellnormal-na-Lymphocytic_B-B_cell-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

DIPK1B LTBP1 CD19

2.76e-04162353ae292318d339305932457bb0e91430594f7a3dfa
ToppCellClub_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

CFH CAV1 PLPP2

2.86e-041643534e25e6362ef793b08de2f4d1dccb6b1fc9c072a5
ToppCell10x5'-blood-Lymphocytic_Invariant-Inducer-like-ILC3|blood / Manually curated celltypes from each tissue

CFH CAV1 WDR72

2.91e-04165353f012a27ece54c0f7b73a2f4f89c6ee8b865f8782
ToppCellInfluenza_Severe-B_memory|Influenza_Severe / Disease group and Cell class

CD19 PLPP2 SCN2A

2.91e-0416535351172acaeb667b34b8b8c7878d67cfa0c4a2dffc
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELF5 CD19 MAMDC2

3.01e-04167353e1b1a952fce27ab9cf16919b290625ff4a75261e
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

DIPK1B CELF5 LTBP1

3.07e-0416835363437b3c3a66f953eaed600965ab193f9cc49da2
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

CFH NHS WDR72

3.07e-04168353a086c306be430adf0632ba53e98cd8014d2de330
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRMT1 FCGR1A GPT2

3.12e-04169353e3100eb587005e160bd0b7990fa57ec49765133d
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-8|TCGA-Liver / Sample_Type by Project: Shred V9

CFH USP2 UPP2

3.23e-04171353c4a919fe3d56ae6df2fcab6686abacc10befc053
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LTBP1 CAV1 MAMDC2

3.23e-04171353fe0665c5ca01b0b2cc8f20d64587f0847c3d215c
ToppCellPND07-28-samps-Myeloid-Macrophage-CD163+_Macrophage|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CFH FCGR1BP WDR72

3.28e-041723539a659442dc41bd2a4361a7e38a7ee37a39781667
ToppCellTCGA-Colorectal-Solid_Tissue_Normal-Colon_normal_tissue|TCGA-Colorectal / Sample_Type by Project: Shred V9

PCSK5 USP2 MAMDC2

3.28e-0417235394842346c84542a5243bd765e49f4af8bc5182db
ToppCellTCGA-Colorectal-Solid_Tissue_Normal-Colon_normal_tissue-Colon_normal_tissue|TCGA-Colorectal / Sample_Type by Project: Shred V9

PCSK5 USP2 MAMDC2

3.28e-041723535d654dd030ed22a701e15c5f09002951d99a52e8
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFH NHS LTBP1

3.34e-041733531f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NHS GPT2 WDR72

3.34e-041733538888434641ea554a9b62c436e87920378eef29cd
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRMT1 FCGR1A FCGR1BP

3.40e-04174353eaaf17a06efc09ed4752b449827b1f0f424d3dad
ToppCell10x5'-blood-Lymphocytic_Invariant-Inducer-like|blood / Manually curated celltypes from each tissue

CFH PLPP2 WDR72

3.40e-0417435351be6f29308c01593978cbee92114151a5916c9c
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH LTBP1 MAMDC2

3.45e-041753531799a7be623dc3bf53ba580a7c47d2619969d708
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELF5 CD19 MAMDC2

3.45e-0417535359249c9e83952d7277010e7be3c779e26399eb5d
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-stromal_related|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ETV5 ZAN WDR72

3.45e-041753532fbffcb843f364645b99d1211698d96092abc5ef
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELF5 CD19 MAMDC2

3.45e-04175353b35cc1357495f2a03a6500f807c6e6f8c877734d
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-stromal_related-Germ|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ETV5 ZAN WDR72

3.45e-04175353d0d5ae2a9357aa183ab720c891d86b80c9822930
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 NHS CAV1

3.51e-041763537292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

USP2 AGBL5 MAMDC2

3.51e-041763534ed73c73972334f6dc4229920205547823252fa0
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 NHS CAV1

3.51e-0417635388ca2f83d8301633232735f39b0683efe49d0b86
ToppCellwk_08-11-Mesenchymal-Chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CFH LTBP1 HAPLN1

3.51e-041763531af28b701c4598ce761f85adbd5d79e4918d265a
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_SSTR1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK5 NHS HAPLN1

3.57e-04177353fdab7b7ddfb06f913b8224c0c80574dc3cf4cbd4
ToppCellRV-11._Adipocyte|RV / Chamber and Cluster_Paper

PCSK5 NHS GPT2

3.63e-04178353278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CFH NHS WDR72

3.63e-04178353544379f5a6145429762258d426b876bb36c112f5
ToppCellAdult-Epithelial-club_cell-D122|Adult / Lineage, Cell type, age group and donor

CFH NHS PLPP2

3.63e-0417835335a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial-Proliferative_Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

CAV1 HDAC7 HAPLN1

3.69e-04179353d24513a404c9b1d37dd47aa1cdb5713b64b88f89
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPT2 MAMDC2 HAPLN1

3.69e-04179353c7c74e26bbf86c5326ee38bac7de111d5414f46b
ToppCellEpithelial-basal_cell|World / Lineage, Cell type, age group and donor

CFH NHS PLPP2

3.69e-04179353d9be6647ec7b22747dc00dce4ea307b6af412dfa
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_mucus_secreting_cell-SMG_mucous-SMG_mucous_L.0.6.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GPT2 PLPP2 UPP2

3.75e-041803538af51245ac1269f318268f574cfaddb0b8c80a53
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NHS GPT2 WDR72

3.75e-041803531363b3254470f6ff98630d1df83a1bdbacc137e0
ToppCell390C-Fibroblasts-Fibroblast-G|390C / Donor, Lineage, Cell class and subclass (all cells)

CFH CAV1 MAMDC2

3.75e-04180353137fc14859c89e1ecd98bee388bb58c04b835847
ToppCellControl-Epithelial-Goblet|Control / Disease state, Lineage and Cell class

CFH NHS PLPP2

3.75e-041803535293d23b8b8ea587239ffde561b70bad01632521
ToppCell390C-Fibroblasts-Fibroblast-G-|390C / Donor, Lineage, Cell class and subclass (all cells)

CFH CAV1 MAMDC2

3.75e-04180353cd6790de050151fedfa2c5ea6ad58b72665414b2
ToppCellMS|World / Condition, Cell_class and T cell subcluster

TMED2 CAV1 CD19

3.81e-0418135399f054a586a95947528dc3fd8043c1bda5e74cc4
ToppCellfacs-Marrow-T_cells-18m-Hematologic-MPP_Fraction_B|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIPK1B CELF5 MAMDC2

3.81e-04181353064057ab36c6d92c36572b73142b42d201709d7b
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH LTBP1 MAMDC2

3.81e-041813539c157de9d3403e092c907599f2a2c16db5b21131
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZC3H12B AGBL5 C1QL3

3.81e-041813533fe648db1cb8326066d8bde3ca1287c5c9af19bd
Drug1ct8

CFH PCSK5 FCGR1A GPT2 HTT

6.45e-06173355CID000444888
Diseaseretinal degeneration (biomarker_via_orthology)

CFH FCGR1A FCGR1BP

4.10e-0628333DOID:8466 (biomarker_via_orthology)
DiseaseAlzheimer disease, polygenic risk score

TYW1 SPPL2A ZAN FCGR1BP GPT2

4.55e-04586335EFO_0030082, MONDO_0004975
Diseasechloride measurement

SPPL2A WDR72

4.83e-0429332EFO_0009284
Diseasehyperuricemia

ETV5 WDR72

6.27e-0433332EFO_0009104
Diseasetransient cerebral ischemia (biomarker_via_orthology)

LTBP1 CAV1 HTT

7.17e-04157333DOID:224 (biomarker_via_orthology)
Diseasepsoriasis (is_marker_for)

CFH CAV1

1.11e-0344332DOID:8893 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
FHSTSKGYMGECGYR

GPT2

336

Q8TD30
HASKRGCFMYGNSFS

AGBL5

436

Q8NDL9
YFFTYHVLMRGGDGT

C1QL3

171

Q5VWW1
YAHGTKLSYTCEGGF

CFH

891

P08603
FHGSYGTFYMCETTL

DIPK1B

286

Q5VUD6
MSGGKYVDSEGHLYT

CAV1

1

Q03135
MYITCAEYTHFYGGK

PPIL2

11

Q13356
VCGKHATMFGQGSYF

TIPARP

551

Q7Z3E1
SHYEQVMTAFGGKGY

HACL1

516

Q9UJ83
GVSGKHCLTFFYHMY

MAMDC2

576

Q7Z304
YHCSGMGKHRYTSAG

FCGR1BP

166

Q92637
MSYFLSYCKAHGGAL

KLHL34

1

Q8N239
GTCTSCAMGYYRFDH

PCSK5

1051

Q92824
LEGSYMCSCHKGYTR

LTBP1

1056

Q14766
SYMRGGYFSSSHEGF

ETV5

311

P41161
RLSFYSGHSSFGMYC

PLPP2

161

O43688
GSSSVRPGLYHYCFM

HTT

1346

P42858
AGKYYCHRGNLTMSF

CD19

256

P15391
YTGMHKGCAFLTYCA

CELF5

81

Q8N6W0
YHCSGMGKHRYTSAG

FCGR1A

166

P12314
GGYHVSAKCFGYMTQ

HDAC7

811

Q8WUI4
VSMGYHKKTYGGYQG

HAPLN1

96

P10915
GHTMCTYDFYEGQGR

UPP2

211

O95045
AGNSGETCYSKYGAM

TRMT1

266

Q9NXH9
TEGYYTSMHFDCGLK

NHS

781

Q6T4R5
GFHGYKCMRQGSFSL

ATRAID

186

Q6UW56
HASGNGTTKDYCMLY

SPPL2A

31

Q8TCT8
GKFYHCINYTTGEMF

SCN2A

1361

Q99250
AICYYHCSFRMTGEG

WDR72

111

Q3MJ13
GDHGYYSMLGDFSKL

ZC3H12B

541

Q5HYM0
SSGKYTFAAHMDGTY

TMED2

76

Q15363
SMLRGRGGCYKHTFY

TYW1

386

Q9NV66
GTTMGGHYTAYCRSP

USP2

551

O75604
AFKRTCGLSYYMGQH

USP32

31

Q8NFA0
TFDGRHFGFMGKCTY

ZAN

1166

Q9Y493