Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	TFIIF-class transcription factor complex binding	GTF2F1 CTDP1	4.67e-05	2	137	2	GO:0001096
GeneOntologyMolecularFunction	beta-catenin binding	SETD1A APC2 AJAP1 CDH2 CDH3 CDH4	1.80e-04	120	137	6	GO:0008013
GeneOntologyBiologicalProcess	regulation of mammary gland epithelial cell proliferation	GATA3 HOXA5 ROBO1 AGAP2	9.92e-06	21	136	4	GO:0033599
GeneOntologyCellularComponent	super elongation complex	AFF2 EAF1 AFF4	5.79e-06	6	140	3	GO:0032783
GeneOntologyCellularComponent	catenin complex	APC2 CDH2 CDH3 CDH4	5.99e-05	32	140	4	GO:0016342
GeneOntologyCellularComponent	adherens junction	DSG3 CCDC85A FRMD4A NDRG1 AJAP1 CDH2 CDH3 CDH4	9.32e-05	212	140	8	GO:0005912
GeneOntologyCellularComponent	postsynapse	SHANK1 WHRN LZTS3 DOK7 APC2 DGKZ ERBIN SENP1 LRFN2 TIAM1 SIPA1L1 APPL1 SAMD14 CDH2 ARHGAP33 MAPK8IP2 AGAP2	4.70e-04	1018	140	17	GO:0098794
Domain	Cadherin_pro	CDH2 CDH3 CDH4	2.01e-05	8	135	3	SM01055
Domain	Cadherin_pro_dom	CDH2 CDH3 CDH4	2.01e-05	8	135	3	IPR014868
Domain	Cadherin_C	DSG3 CDH2 CDH3 CDH4	2.94e-05	25	135	4	PF01049
Domain	Cadherin_cytoplasmic-dom	DSG3 CDH2 CDH3 CDH4	2.94e-05	25	135	4	IPR000233
Domain	Catenin_binding_dom	DSG3 CDH2 CDH3 CDH4	5.39e-05	29	135	4	IPR027397
Domain	-	DSG3 CDH2 CDH3 CDH4	5.39e-05	29	135	4	4.10.900.10
Domain	FAM122	PABIR1 PABIR2	1.55e-04	3	135	2	IPR026716
Domain	-	MSH3 MSH4	1.55e-04	3	135	2	3.30.420.110
Domain	DNA_mmatch_repair_MutS_con_dom	MSH3 MSH4	3.08e-04	4	135	2	IPR007860
Domain	MutS_II	MSH3 MSH4	3.08e-04	4	135	2	PF05188
Domain	TF_AF4/FMR2	AFF2 AFF4	3.08e-04	4	135	2	IPR007797
Domain	AF-4	AFF2 AFF4	3.08e-04	4	135	2	PF05110
Domain	SH3_2	SHANK1 DOCK3 SH3KBP1 ARHGEF38 ARHGAP33	3.99e-04	86	135	5	PF07653
Domain	SH3_2	SHANK1 DOCK3 SH3KBP1 ARHGEF38 ARHGAP33	3.99e-04	86	135	5	IPR011511
Domain	MUTSd	MSH3 MSH4	5.11e-04	5	135	2	SM00533
Domain	MUTSac	MSH3 MSH4	5.11e-04	5	135	2	SM00534
Domain	MutS_V	MSH3 MSH4	5.11e-04	5	135	2	PF00488
Domain	DNA_mismatch_repair_MutS_clamp	MSH3 MSH4	5.11e-04	5	135	2	IPR007861
Domain	DNA_MISMATCH_REPAIR_2	MSH3 MSH4	5.11e-04	5	135	2	PS00486
Domain	MutS_IV	MSH3 MSH4	5.11e-04	5	135	2	PF05190
Domain	MutS_III	MSH3 MSH4	5.11e-04	5	135	2	PF05192
Domain	DNA_mismatch_repair_MutS_C	MSH3 MSH4	5.11e-04	5	135	2	IPR000432
Domain	DNA_mismatch_repair_MutS_core	MSH3 MSH4	5.11e-04	5	135	2	IPR007696
Domain	PDZ	SHANK1 WHRN ERBIN MAST4 TIAM1 SIPA1L1	5.63e-04	141	135	6	PF00595
Domain	PDZ	SHANK1 WHRN ERBIN MAST4 TIAM1 SIPA1L1	7.26e-04	148	135	6	SM00228
Domain	-	SHANK1 WHRN ERBIN MAST4 TIAM1 SIPA1L1	7.79e-04	150	135	6	2.30.42.10
Domain	PDZ	SHANK1 WHRN ERBIN MAST4 TIAM1 SIPA1L1	8.07e-04	151	135	6	PS50106
Domain	PDZ	SHANK1 WHRN ERBIN MAST4 TIAM1 SIPA1L1	8.35e-04	152	135	6	IPR001478
Domain	AT_hook	KMT2A DOT1L ZNF653	9.51e-04	27	135	3	SM00384
Domain	AT_hook_DNA-bd_motif	KMT2A DOT1L ZNF653	9.51e-04	27	135	3	IPR017956
Domain	SH3	SHANK1 DOCK3 CACNB2 SH3KBP1 ARHGEF38 ARHGAP33 MAPK8IP2	9.96e-04	216	135	7	SM00326
Domain	SH3	SHANK1 DOCK3 CACNB2 SH3KBP1 ARHGEF38 ARHGAP33 MAPK8IP2	9.96e-04	216	135	7	PS50002
Domain	Cadherin_pro	CDH2 CDH4	1.06e-03	7	135	2	PF08758
Domain	PH_dom-like	DOK7 RALGPS2 ARHGEF25 FRMD4A CCM2 TIAM1 APPL1 PLCB2 MAPK8IP2 AGAP2	1.07e-03	426	135	10	IPR011993
Domain	SH3_domain	SHANK1 DOCK3 CACNB2 SH3KBP1 ARHGEF38 ARHGAP33 MAPK8IP2	1.11e-03	220	135	7	IPR001452
Domain	UBA	UBQLN4 TNRC6C HUWE1	1.30e-03	30	135	3	SM00165
Domain	PID	CCM2 APPL1 MAPK8IP2	1.57e-03	32	135	3	PS01179
Domain	-	DOK7 RALGPS2 ARHGEF25 FRMD4A CCM2 TIAM1 APPL1 MAPK8IP2 AGAP2	2.17e-03	391	135	9	2.30.29.30
Domain	UBA	UBQLN4 TNRC6C HUWE1	2.21e-03	36	135	3	PF00627
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	SHANK1 DOCK3 ZSWIM8 HIVEP2 CLIP2 CEP85L HIPK1 UBR4 APC2 UBQLN4 CHD9 SMG5 MSH3 NUP42 HUWE1 CCDC85A NDRG1 TIAM1 SIPA1L1 ROBO1 APPL1 KDM4A AFF4 MAPK8IP2 AGAP2	7.32e-11	1285	141	25	35914814
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SHANK1 CACNB2 LZTS3 CLIP2 NHSL2 UBR4 APC2 SH3KBP1 DGKZ HUWE1 ERBIN SENP1 MAGED2 SIPA1L1 STON2 APPL1 CDH2 AFF4 MAPK8IP2 AGAP2	2.37e-09	963	141	20	28671696
Pubmed	A human MAP kinase interactome.	SHANK1 HIVEP2 CLIP2 HIPK1 SREBF2 NUP214 MUC12 NUP42 ERBIN CIC TSC22D1 ROBO1 NKTR ARHGAP33	1.29e-08	486	141	14	20936779
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	PABIR1 HIVEP2 CEP85L RALGPS2 CBARP ERBIN PABIR2 CIC STIM1 MAST4 NDRG1 FAM13A TIAM1 SIPA1L1 RAB11FIP5 KMT2A SRRM2 CFAP97	1.45e-08	861	141	18	36931259
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	PUM2 CDK11A ISL2 NUP214 HUWE1 ERBIN CIC KANSL3 NDRG1 FAM13A MAGED2 SIPA1L1 CTDP1 KMT2A APPL1 SNAPC4 SRRM2	1.84e-08	774	141	17	15302935
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DOCK3 SETD1A ANKS6 HIVEP2 SPEG UBR4 NUP214 SMG5 TNRC6C HUWE1 TNFRSF21 CIC KANSL3 MTHFR TMCC2 CTDP1 UNKL DOT1L SNAPC4 ARHGAP33	2.35e-08	1105	141	20	35748872
Pubmed	Human transcription factor protein interaction networks.	SETD1A UBR4 SH3KBP1 GATA3 PUM2 CDK11A ISL2 NUP214 SMG5 TNRC6C ERBIN CIC HOXA5 KANSL3 ARID1B MAGED2 UBTF KMT2A SP9 EIF3H DOT1L SRRM2	7.62e-08	1429	141	22	35140242
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	DOCK3 SH3KBP1 NUP214 ZNF362 NUP42 HUWE1 ARHGEF25 FAM13A TIAM1 MAGED2 ARHGAP29 KMT2A ROBO1 APPL1 NKTR CKAP4 ARHGAP33	2.04e-07	916	141	17	32203420
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	DOCK3 SETD1A CHD9 HUWE1 CIC MAST4 SRRM2	2.37e-07	104	141	7	9205841
Pubmed	Developmental defects in mouse embryos lacking N-cadherin.	CDH2 CDH3 CDH4	2.60e-07	4	141	3	9015265
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	CLIP2 PUM2 SMG5 TNRC6C ERBIN FBXL7 SIPA1L1 TMCC2 APPL1	3.78e-07	225	141	9	12168954
Pubmed	Phosphoproteomic analysis of the developing mouse brain.	PABIR1 HUWE1 RTN2 CIC FRMD4A TMCC2 APPL1 SAMD14 SRRM2	7.96e-07	246	141	9	15345747
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	WHRN HIPK1 TRO SPEG PUM2 NUP214 TNRC6C ERBIN LRFN2 SIPA1L1 SRRM2	9.30e-07	407	141	11	12693553
Pubmed	A census of human transcription factors: function, expression and evolution.	MYF6 HIVEP2 GATA3 SREBF2 ISL2 CIC EVX2 HOXA5 TSC22D1 NFE2L1 UBTF KMT2A SP9 UNKL SNAPC4 ZNF653	9.41e-07	908	141	16	19274049
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZSWIM8 UBR4 CHD9 HUWE1 CIC FRMD4A	1.54e-06	87	141	6	12465718
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	DOCK3 SETD1A AFF2 TRO UBR4 APC2 GLIS3 NUP214 CIC NFE2L1 STON2	1.58e-06	430	141	11	35044719
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	LZTS3 CLIP2 APC2 DGKZ ERBIN ACAN SIPA1L1 AP3B2 CDH2 MAPK8IP2 AGAP2	1.58e-06	430	141	11	32581705
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	CLIP2 TMEM121B HIPK1 SH3KBP1 CBARP SIPA1L1 RAB11FIP5 SAMD14 SRRM2 AGAP2	1.67e-06	347	141	10	17114649
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	CACNB2 RALGPS2 SREBF2 MARCHF7 DGKZ CHD2 HUWE1 ERBIN EZHIP ARID1B NFE2L1 UBTF SIPA1L1 AEBP2 ADAMTS18 DOT1L AFF4	2.06e-06	1084	141	17	11544199
Pubmed	Genetic dissection of cadherin function during nephrogenesis.	CDH2 CDH3 CDH4	2.26e-06	7	141	3	11839813
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	SHANK1 DOCK3 LZTS3 UBR4 SH3KBP1 ETFA CBARP HUWE1 ERBIN STIM1 FRMD4A NDRG1 SIPA1L1 TMCC2 APPL1 CKAP4 AGAP2	3.97e-06	1139	141	17	36417873
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	PABIR1 ZSWIM8 SCHIP1 ANKS6 MARCHF7 DGKZ TNRC6C SOWAHC ERBIN PABIR2 GTF2F1 EAF1 MAGED2 ARHGAP29 RAB11FIP5 EIF3H	5.21e-06	1038	141	16	26673895
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	GATA3 GLIS3 ISL2 NUP42 CIC TSC22D1 PER3 NFE2L1 UBTF AEBP2 KDM4A EIF3H SNAPC4 ZNF653	5.68e-06	808	141	14	20412781
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PABIR1 CBARP ZNF362 HUWE1 ERBIN PABIR2 CIC STIM1 GTF2F1 ARID1B TIAM1 UBTF RAB11FIP5 ROBO1 CKAP4 SRRM2	5.95e-06	1049	141	16	27880917
Pubmed	Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131.	CHD9 NUP214 SENP1 NFE2L1 KMT2A KDM4A	6.04e-06	110	141	6	26841866
Pubmed	A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription.	KMT2A DOT1L AFF4	7.67e-06	10	141	3	20153263
Pubmed	CBX8, a polycomb group protein, is essential for MLL-AF9-induced leukemogenesis.	KMT2A DOT1L AFF4	7.67e-06	10	141	3	22094252
Pubmed	Sonic hedgehog signaling regulates actin cytoskeleton via Tiam1-Rac1 cascade during spine formation.	DGKZ FRMD4A TIAM1	1.05e-05	11	141	3	20654717
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	SETD1A UBR4 GATA3 ERBIN SENP1 ARID1B KMT2A SRRM2 AFF4	1.13e-05	341	141	9	32971831
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	MUC19 NUP214 NUP42 STIM1 SENP1 ARID1B	1.15e-05	123	141	6	26912792
Pubmed	MicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord.	ISL2 HOXA5 CDH2	1.40e-05	12	141	3	28337978
Pubmed	Molecular cloning of mouse pancreatic islet R-cadherin: differential expression in endocrine and exocrine tissue.	CDH2 CDH4	1.63e-05	2	141	2	8247017
Pubmed	The generation and in vivo differentiation of murine embryonal stem cells genetically null for either N-cadherin or N- and P-cadherin.	CDH2 CDH3	1.63e-05	2	141	2	10707907
Pubmed	Distinct Responses to Menin Inhibition and Synergy with DOT1L Inhibition in KMT2A-Rearranged Acute Lymphoblastic and Myeloid Leukemia.	KMT2A DOT1L	1.63e-05	2	141	2	38892207
Pubmed	In vivo intra-articular contrast enhanced μCT imaging of mouse knee cartilage.	ACAN DOT1L	1.63e-05	2	141	2	36436817
Pubmed	MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L.	KMT2A DOT1L	1.63e-05	2	141	2	21741597
Pubmed	DOT1L inhibition sensitizes MLL-rearranged AML to chemotherapy.	KMT2A DOT1L	1.63e-05	2	141	2	24858818
Pubmed	HUWE1 ubiquitylates and degrades the RAC activator TIAM1 promoting cell-cell adhesion disassembly, migration, and invasion.	HUWE1 TIAM1	1.63e-05	2	141	2	25543140
Pubmed	Switch of cadherin expression as a diagnostic tool for Leydig cell tumours.	CDH2 CDH3	1.63e-05	2	141	2	23398382
Pubmed	The role of DOT1L in the maintenance of leukemia gene expression.	KMT2A DOT1L	1.63e-05	2	141	2	27151433
Pubmed	Fragile XE-associated familial mental retardation protein 2 (FMR2) acts as a potent transcription activator.	AFF2 AFF4	1.63e-05	2	141	2	11355014
Pubmed	The Role of Dot1l in Prenatal and Postnatal Murine Chondrocytes and Trabecular Bone.	ACAN DOT1L	1.63e-05	2	141	2	32083237
Pubmed	NMR structure of a complex containing the TFIIF subunit RAP74 and the RNA polymerase II carboxyl-terminal domain phosphatase FCP1.	GTF2F1 CTDP1	1.63e-05	2	141	2	12732728
Pubmed	N-cadherin and P-cadherin are biomarkers for invasion, metastasis, and poor prognosis of gallbladder carcinomas.	CDH2 CDH3	1.63e-05	2	141	2	24636838
Pubmed	Postnatal lethality of P-cadherin/desmoglein 3 double knockout mice: demonstration of a cooperative effect of these cell adhesion molecules in tissue homeostasis of stratified squamous epithelia.	DSG3 CDH3	1.63e-05	2	141	2	10771476
Pubmed	Molecular mechanism of recruitment of TFIIF- associating RNA polymerase C-terminal domain phosphatase (FCP1) by transcription factor IIF.	GTF2F1 CTDP1	1.63e-05	2	141	2	12591941
Pubmed	Activation of the repulsive receptor Roundabout inhibits N-cadherin-mediated cell adhesion.	ROBO1 CDH2	1.63e-05	2	141	2	12360290
Pubmed	Functional cis-heterodimers of N- and R-cadherins.	CDH2 CDH4	1.63e-05	2	141	2	10662782
Pubmed	The molecular mechanics of mixed lineage leukemia.	KMT2A DOT1L	1.63e-05	2	141	2	26923329
Pubmed	Glutamatergic Dysfunction and Synaptic Ultrastructural Alterations in Schizophrenia and Autism Spectrum Disorder: Evidence from Human and Rodent Studies.	SHANK1 LRFN2 MAPK8IP2	1.81e-05	13	141	3	33374598
Pubmed	MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia.	KMT2A DOT1L AFF4	2.30e-05	14	141	3	20854876
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	AFF2 CHD9 CHD2 MAGED2 SIPA1L1 AP3B2 KMT2A	2.37e-05	208	141	7	33230847
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	AFF2 ETFA RALGPS2 GATA3 CDK11A CHD2 MSH3 MSH4 ERBIN MAGED2 AEBP2 ADAMTS18	2.48e-05	686	141	12	29987050
Pubmed	p63 control of desmosome gene expression and adhesion is compromised in AEC syndrome.	DSG3 CKAP4 CDH3	2.86e-05	15	141	3	23108156
Pubmed	Differential Spatiotemporal Expression of Type I and Type II Cadherins Associated With the Segmentation of the Central Nervous System and Formation of Brain Nuclei in the Developing Mouse.	CDH2 CDH3 CDH4	2.86e-05	15	141	3	33833667
Pubmed	No evidence of involvement of E-cadherin in cell fate specification or the segregation of Epi and PrE in mouse blastocysts.	CDH2 CDH3 CDH4	2.86e-05	15	141	3	30735538
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	HIVEP2 ZNF185 GATA3 SREBF2 RTN2 CIC EVX2 NDRG1 NFE2L1 UBTF KMT2A KDM4A	3.42e-05	709	141	12	22988430
Pubmed	Cadherin expression in the developing mouse olfactory system.	CDH2 CDH3 CDH4	3.51e-05	16	141	3	17278136
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	SPEG UBR4 KANSL3 FRMD4A APPL1 CFAP97	3.95e-05	153	141	6	10718198
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	CHD9 CHD2 MSH3 ZNF362 CIC UBTF KMT2A KDM4A DOT1L SNAPC4 AFF4	4.04e-05	608	141	11	36089195
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	CHD2 ARID1B AEBP2 KDM4A CDH3 CDH4	4.56e-05	157	141	6	30186101
Pubmed	Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.	SETD1A KMT2A KDM4A DOT1L	4.76e-05	49	141	4	34368113
Pubmed	Cadherins and tissue formation: integrating adhesion and signaling.	CDH2 CDH3	4.88e-05	3	141	2	10333730
Pubmed	Increased susceptibility to develop spontaneous and post-traumatic osteoarthritis in Dot1l-deficient mice.	ACAN DOT1L	4.88e-05	3	141	2	30513362
Pubmed	Cooperative gene activation by AF4 and DOT1L drives MLL-rearranged leukemia.	KMT2A DOT1L	4.88e-05	3	141	2	28394257
Pubmed	Targeting DOT1L and HOX gene expression in MLL-rearranged leukemia and beyond.	KMT2A DOT1L	4.88e-05	3	141	2	26118503
Pubmed	IQCJ-SCHIP1, a novel fusion transcript encoding a calmodulin-binding IQ motif protein.	SCHIP1 IQCJ-SCHIP1	4.88e-05	3	141	2	17045569
Pubmed	Regulation of CHD2 expression by the Chaserr long noncoding RNA gene is essential for viability.	CHD2 CDH2	4.88e-05	3	141	2	31704914
Pubmed	The role of N-cadherin/c-Jun/NDRG1 axis in the progression of prostate cancer.	NDRG1 CDH2	4.88e-05	3	141	2	34512147
Pubmed	Knock-down of ZBED6 in insulin-producing cells promotes N-cadherin junctions between beta-cells and neural crest stem cells in vitro.	ZBED6 CDH2	4.88e-05	3	141	2	26750727
Pubmed	Aberrant Expression of E-cadherin, N-cadherin, and P-cadherin in Clear Cell Renal Cell Carcinoma: Association With Adverse Clinicopathologic Factors and Poor Prognosis.	CDH2 CDH3	4.88e-05	3	141	2	32341236
Pubmed	The coactivator host cell factor-1 mediates Set1 and MLL1 H3K4 trimethylation at herpesvirus immediate early promoters for initiation of infection.	SETD1A KMT2A	4.88e-05	3	141	2	17578910
Pubmed	Systematic analysis of E-, N- and P-cadherin expression in mouse eye development.	CDH2 CDH3	4.88e-05	3	141	2	12126948
Pubmed	Expression of E-, P- and N-Cadherin and Its Clinical Significance in Cervical Squamous Cell Carcinoma and Precancerous Lesions.	CDH2 CDH3	4.88e-05	3	141	2	27223886
Pubmed	Characterization of cyclin L1 and L2 interactions with CDK11 and splicing factors: influence of cyclin L isoforms on splice site selection.	CCNL2 CDK11A	4.88e-05	3	141	2	18216018
Pubmed	NMR structure of a complex formed by the carboxyl-terminal domain of human RAP74 and a phosphorylated peptide from the central domain of the FCP1 phosphatase.	GTF2F1 CTDP1	4.88e-05	3	141	2	19215094
Pubmed	Comparative expression analysis of the MAGED genes during embryogenesis and brain development.	TRO MAGED2	4.88e-05	3	141	2	15162511
Pubmed	Leukemic transformation by the MLL-AF6 fusion oncogene requires the H3K79 methyltransferase Dot1l.	KMT2A DOT1L	4.88e-05	3	141	2	23361907
Pubmed	The prognostic value of cadherin switch in bladder cancer.	CDH2 CDH3	4.88e-05	3	141	2	20204300
Pubmed	Requirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation.	KMT2A DOT1L	4.88e-05	3	141	2	21398221
Pubmed	Functional characterization of the AFF (AF4/FMR2) family of RNA-binding proteins: insights into the molecular pathology of FRAXE intellectual disability.	AFF2 AFF4	4.88e-05	3	141	2	21330300
Pubmed	Set1/MLL complex is indispensable for the transcriptional ability of heat shock transcription factor 2.	SETD1A KMT2A	4.88e-05	3	141	2	26478434
Pubmed	Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: an exome sequencing study.	HIVEP2 CHD2	4.88e-05	3	141	2	23020937
Pubmed	Solution structure of the carboxyl-terminal domain of RAP74 and NMR characterization of the FCP1-binding sites of RAP74 and human TFIIB.	GTF2F1 CTDP1	4.88e-05	3	141	2	12578358
Pubmed	Differential expression of neural cell adhesion molecule and cadherins in pancreatic islets, glucagonomas, and insulinomas.	CDH2 CDH4	4.88e-05	3	141	2	1406710
Pubmed	A higher-order configuration of the heterodimeric DOT1L-AF10 coiled-coil domains potentiates their leukemogenenic activity.	KMT2A DOT1L	4.88e-05	3	141	2	31527241
Pubmed	AF5q31, a newly identified AF4-related gene, is fused to MLL in infant acute lymphoblastic leukemia with ins(5;11)(q31;q13q23).	KMT2A AFF4	4.88e-05	3	141	2	10588740
Pubmed	The N-recognin UBR4 of the N-end rule pathway is required for neurogenesis and homeostasis of cell surface proteins.	UBR4 CDH2	4.88e-05	3	141	2	30157281
Pubmed	The role of KDM4A-mediated histone methylation on temozolomide resistance in glioma cells through the HUWE1/ROCK2 axis.	HUWE1 KDM4A	4.88e-05	3	141	2	37873881
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	WHRN HIPK1 UBR4 UNKL SRRM2 ZNF653 MAPK8IP2	4.89e-05	233	141	7	37704626
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	CCNL2 ZSWIM8 CHD9 ZNF362 SOWAHC SENP1 ARID1B EAF1 MTHFR SIPA1L1 RAB11FIP5 CKAP4 SRRM2 AFF4 ARHGAP33	5.06e-05	1116	141	15	31753913
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	CACNB2 CBARP ERBIN STIM1 RAB11FIP5 ROBO1 APPL1 CKAP4 CDH2	5.87e-05	421	141	9	36976175
Pubmed	Teashirt 1 (Tshz1) is essential for the development, survival and function of hypoglossal and phrenic motor neurons in mouse.	GATA3 ISL2 HOXA5	6.03e-05	19	141	3	31427287
Pubmed	E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton.	CDH2 CDH3 CDH4	7.07e-05	20	141	3	7806582
Pubmed	SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.	NUP214 NUP42 GTF2F1 SENP1 TIAM1 CKAP4 SRRM2	7.61e-05	250	141	7	33536335
Pubmed	Presenilin-dependent receptor processing is required for axon guidance.	GATA3 ISL2 ROBO1	8.22e-05	21	141	3	21215373
Pubmed	New nomenclature for chromatin-modifying enzymes.	SETD1A KMT2A KDM4A DOT1L	8.65e-05	57	141	4	18022353
Pubmed	Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.	CLIP2 CEP85L SH3KBP1 KRT79 TIAM1	9.26e-05	111	141	5	22558309
Pubmed	CDK11(p58) kinase activity is required to protect sister chromatid cohesion at centromeres in mitosis.	CCNL2 CDK11A	9.74e-05	4	141	2	24436071
Pubmed	c-Myb and GATA-3 cooperatively regulate IL-13 expression via conserved GATA-3 response element and recruit mixed lineage leukemia (MLL) for histone modification of the IL-13 locus.	GATA3 KMT2A	9.74e-05	4	141	2	22039304
Interaction	NFKBIL1 interactions	SETD1A CHD9 CCDC85A EAF1 UBTF AP3B2 TNFRSF1B SNAPC4 SRRM2 AFF4	9.36e-10	93	140	10	int:NFKBIL1
Interaction	YWHAH interactions	PABIR1 HIVEP2 NHSL2 CEP85L SPEG RALGPS2 CBARP HUWE1 ERBIN PABIR2 CIC STIM1 FRMD4A MAST4 NDRG1 FAM13A TIAM1 SIPA1L1 KCNK3 RAB11FIP5 KMT2A APPL1 NKTR SRRM2 CFAP97	1.50e-07	1102	140	25	int:YWHAH
Interaction	YWHAG interactions	PABIR1 HIVEP2 NHSL2 CEP85L SPEG RALGPS2 CBARP HUWE1 ERBIN PABIR2 CIC STIM1 FRMD4A MAST4 NDRG1 FAM13A TIAM1 SIPA1L1 KCNK3 ARHGAP29 RAB11FIP5 KMT2A APPL1 NKTR SRRM2 CFAP97	4.23e-07	1248	140	26	int:YWHAG
Interaction	SYT2 interactions	SETD1A CHD9 SMG5 MTHFR AP3B2 STON2 CTDP1 AFF4	1.02e-05	150	140	8	int:SYT2
Interaction	EDA interactions	SETD1A UBR4 PTGIR UBTF AP3B2 SRRM2 AFF4	1.40e-05	113	140	7	int:EDA
Interaction	YWHAE interactions	PABIR1 HIVEP2 CEP85L RALGPS2 CDK11A CBARP HUWE1 ERBIN PABIR2 CIC STIM1 FRMD4A MAST4 FAM13A TIAM1 SIPA1L1 KCNK3 RAB11FIP5 KMT2A APPL1 DOT1L SRRM2 ARHGAP33	1.80e-05	1256	140	23	int:YWHAE
Interaction	PIP4K2A interactions	CHD9 CCDC85A HOXA5 GTF2F1 EAF1 UBTF CKAP4 SRRM2 AFF4	2.06e-05	216	140	9	int:PIP4K2A
Interaction	YWHAB interactions	PABIR1 CEP85L SPEG RALGPS2 CBARP ERBIN PABIR2 CIC STIM1 MAST4 FAM13A TIAM1 SIPA1L1 KCNK3 RAB11FIP5 KMT2A APPL1 DOT1L SRRM2 AGAP2	2.38e-05	1014	140	20	int:YWHAB
Interaction	POLR1G interactions	UBR4 CDK11A CHD9 CHD2 ZNF362 HUWE1 CIC GTF2F1 UBTF KMT2A DOT1L SRRM2 AFF4	3.76e-05	489	140	13	int:POLR1G
Interaction	MDK interactions	SETD1A UBQLN4 CHD9 UBTF SRRM2 AFF4	4.14e-05	91	140	6	int:MDK
GeneFamily	CD molecules\|Type I classical cadherins	CDH2 CDH3 CDH4	1.35e-06	5	94	3	1185
GeneFamily	PDZ domain containing	SHANK1 WHRN ERBIN MAST4 TIAM1 SIPA1L1	1.42e-04	152	94	6	1220
GeneFamily	AF4/FMR2 family\|Super elongation complex	AFF2 AFF4	1.59e-04	4	94	2	1145
GeneFamily	CD molecules\|Mucins	MUC19 MUC12 MUC22	1.69e-04	21	94	3	648
GeneFamily	MutS homologs\|PWWP domain containing	MSH3 MSH4	2.65e-04	5	94	2	1026
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	SETD1A KMT2A DOT1L	7.25e-04	34	94	3	487
GeneFamily	AF4/FMR2 family\|Super elongation complex	AFF2 AFF4	9.40e-04	9	94	2	1280
GeneFamily	Sterile alpha motif domain containing	SHANK1 ANKS6 STIM1 SAMD14	1.14e-03	88	94	4	760
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	FAM13A ARHGAP29 ARHGAP33	2.24e-03	50	94	3	721
GeneFamily	X-linked mental retardation\|Rho GTPase activating proteins\|BAR-PH domain containing	APPL1 AGAP2	3.46e-03	17	94	2	1291
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGEF38 ARHGEF25 TIAM1	4.92e-03	66	94	3	722
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HNBML5	ARPP21 AFF2 TMEM121B SPEG APC2 GATA3 MUC19 CCDC85A AJAP1 ROBO1 DOT1L SAMD14 CDH4 NOVA1	2.34e-07	465	141	14	M39066
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	DOCK3 ARPP21 AFF2 LZTS3 CEP85L TMEM121B SPEG APC2 SH3KBP1 GATA3 MUC19 TNRC6C CCDC85A MAST4 AJAP1 AP3B2 ROBO1 SAMD14 CDH4 MAPK8IP2 NOVA1	5.02e-07	1106	141	21	M39071
Coexpression	GSE40666_WT_VS_STAT1_KO_CD8_TCELL_UP	RALGPS2 MARCHF7 PTGIR CIC CCM2 NDRG1 SIPA1L1 ARHGAP29 ARHGAP33	1.44e-06	200	141	9	M9205
Coexpression	YAGI_AML_WITH_T_8_21_TRANSLOCATION	NUP214 TNFRSF21 PTGIR STIM1 PTPRCAP MAGED2 SIPA1L1 KMT2A ROBO1 CDH2 CDH4	5.76e-06	372	141	11	M19261
Coexpression	GSE25146_UNSTIM_VS_HELIOBACTER_PYLORI_LPS_STIM_AGS_CELL_DN	CCNL2 MARCHF7 ERBIN PLCB2 NKTR SNAPC4 AFF4	3.34e-05	166	141	7	M8129
Coexpression	MURARO_PANCREAS_BETA_CELL	HIVEP2 SPEG GLIS3 CHD9 HUWE1 MAST4 NDRG1 PER3 TIAM1 NFE2L1 KCNK3 RAB11FIP5 ROBO1 APPL1 EIF3H AFF4	5.19e-05	946	141	16	M39169
Coexpression	GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN	SETD1A NUP214 SMG5 CIC KDM4A DOT1L SNAPC4 SRRM2 CAPN15	9.34e-05	338	141	9	M17094
Coexpression	GSE15767_MED_VS_SCS_MAC_LN_DN	DOCK3 HIVEP2 KRT24 SIPA1L1 APPL1 EIF3H AFF4	1.05e-04	199	141	7	M3585
Coexpression	ENK_UV_RESPONSE_EPIDERMIS_DN	HIVEP2 DSG3 GATA3 ERBIN NDRG1 PER3 ARHGAP29 KMT2A ROBO1 CDH3 AFF4	1.07e-04	512	141	11	M4508
Coexpression	GSE26669_CD4_VS_CD8_TCELL_IN_MLR_COSTIM_BLOCK_UP	HIVEP2 GATA3 SREBF2 ERBIN PTGIR CCM2 EAF1	1.08e-04	200	141	7	M4672
Coexpression	GSE8685_IL2_ACT_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_UP	CLIP2 CIC CCDC85A ARID1B PTPRCAP TIAM1 CAPN15	1.08e-04	200	141	7	M331
Coexpression	GSE20754_WT_VS_TCF1_KO_MEMORY_CD8_TCELL_UP	LZTS3 CHD2 SMG5 SOWAHC NDRG1 CKAP4 AFF4	1.08e-04	200	141	7	M7783
Coexpression	GSE360_DC_VS_MAC_B_MALAYI_HIGH_DOSE_DN	HIVEP2 SREBF2 CBARP MSH4 PTGIR RAB11FIP5 TNFRSF1B	1.08e-04	200	141	7	M5186
Coexpression	GSE16385_UNTREATED_VS_12H_ROSIGLITAZONE_IFNG_TNF_TREATED_MACROPHAGE_UP	PABIR1 TRO GATA3 LRFN2 PER3 TMCC2 TNFRSF1B	1.08e-04	200	141	7	M7889
Coexpression	FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_UP	GATA3 SREBF2 TSC22D1 TIAM1 CDH4	1.21e-04	89	141	5	M6434
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NHSL2 JPH2 CCDC85A FRMD4A LRFN2 FBXL7 ARHGAP29 ADAMTS18 ROBO1	6.70e-09	181	141	9	5f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NHSL2 JPH2 CCDC85A FRMD4A LRFN2 FBXL7 ARHGAP29 ADAMTS18 ROBO1	6.70e-09	181	141	9	c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	CEP85L HIPK1 CHD2 HUWE1 ARID1B FAM13A ZBED6 KMT2A NKTR	9.33e-09	188	141	9	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	HIPK1 CDK11A ZNF362 ERBIN PER3 NFE2L1 MTHFR PLCB2	5.01e-08	162	141	8	810881210e015c788814e4fe8d7a24c929cf2621
ToppCell	Brain_organoid-organoid_Kanton_Nature\|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.	MARCHF7 CHD9 SP9 NKTR SRRM2 CDH2 CFAP97 NOVA1	1.39e-07	185	141	8	857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NHSL2 DOK7 CCDC85A FRMD4A LRFN2 FBXL7 ROBO1 CDH2	1.39e-07	185	141	8	34fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NHSL2 DOK7 CCDC85A FRMD4A LRFN2 FBXL7 ROBO1 CDH2	1.39e-07	185	141	8	8816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NHSL2 DOK7 CCDC85A FRMD4A LRFN2 FBXL7 ARHGAP29 ROBO1	1.58e-07	188	141	8	b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NHSL2 DOK7 CCDC85A FRMD4A LRFN2 FBXL7 ARHGAP29 ROBO1	1.58e-07	188	141	8	874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	ERBIN ARID1B NDRG1 ADAMTS18 ROBO1 NKTR SRRM2 AFF4	1.93e-07	193	141	8	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	COVID_non-vent-Lymphocytic-T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	HIVEP2 GATA3 CHD2 TNRC6C MAST4 PTPRCAP KMT2A NKTR	2.09e-07	195	141	8	4bdedd924564a260841a9153604026b57487c83d
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DOCK3 ANKS6 SH3KBP1 GATA3 KRT24 PTPRCAP AGAP2	4.73e-07	148	141	7	438fe292d29be0206e1d9fd59ede5f8368f13665
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell-D175\|Adult / Lineage, Cell type, age group and donor	CACNB2 ADAMTSL1 SPEG JPH2 CBARP ARHGEF25 IQCJ-SCHIP1	1.07e-06	167	141	7	c4e321bb87512ea839f324c92c0f1afea891483f
ToppCell	COVID-19-kidney-Epi_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	NHSL2 JPH2 CCDC85A FRMD4A FBXL7 ARHGAP29 CDH2	1.69e-06	179	141	7	e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCHIP1 AFF2 SPEG JPH2 MAGED2 KCNK3 CDH2	1.69e-06	179	141	7	f5bb4d3a27d56698473219970e764084096cc582
ToppCell	facs-Lung-nan-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCHIP1 AFF2 TNFRSF21 AJAP1 MAGED2 KCNK3 CDH2	1.69e-06	179	141	7	7078022e60faa86444f2a2c6eb9f767cc66b5cfa
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCHIP1 AFF2 SPEG JPH2 MAGED2 KCNK3 CDH2	1.69e-06	179	141	7	fa03ec3cc0132f977b4cb28e7b23789732375183
ToppCell	facs-Lung-nan-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCHIP1 AFF2 TNFRSF21 AJAP1 MAGED2 KCNK3 CDH2	1.69e-06	179	141	7	d4a975d8ffa5e77fb5c0ec05bf9c8f843c77ce07
ToppCell	droplet-Lung-nan-18m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCHIP1 AFF2 SPEG JPH2 MAGED2 KCNK3 CDH2	1.76e-06	180	141	7	f6a05b3751b01e74b2de8440801b0eb2e723c199
ToppCell	droplet-Lung-nan-18m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCHIP1 AFF2 SPEG JPH2 MAGED2 KCNK3 CDH2	1.76e-06	180	141	7	dfc75ae4395ff46fbec2c54915d98ead5a1ba1a1
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AFF2 PER3 TIAM1 KCNK3 SAMD14 CDH2 NOVA1	1.76e-06	180	141	7	8bf6e8b6b45ce42f8c5f23e7cd1752ec8b3fa2d2
ToppCell	IPF-Stromal-SMC\|World / Disease state, Lineage and Cell class	CACNB2 SPEG JPH2 ARHGEF25 PTGIR ACAN KCNK3	2.34e-06	188	141	7	b66264e8f8d536ed2beec31e6746c687718f239b
ToppCell	IPF-Stromal-SMC\|IPF / Disease state, Lineage and Cell class	CACNB2 SPEG JPH2 ARHGEF25 PTGIR ACAN KCNK3	2.34e-06	188	141	7	e98b24c0de41285f01f7ac194ff0a1b59fd5c333
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB2 SPEG JPH2 PTGIR FRMD4A FBXL7 ACAN	2.43e-06	189	141	7	7fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB2 SPEG JPH2 PTGIR FRMD4A FBXL7 ACAN	2.43e-06	189	141	7	06b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-bronchial_smooth_muscle_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK3 CACNB2 SPEG JPH2 FBXL7 KCNK3 INPP5J	2.43e-06	189	141	7	4dc32b463546bbe7250dddd281b92ad17ec22da1
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Airway_Smooth_Muscle\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK3 CACNB2 SPEG JPH2 FBXL7 KCNK3 INPP5J	2.43e-06	189	141	7	0d06bf0d7191d13a1c4f30a7881e7ea1093bfd6f
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AFF2 TNFRSF21 PTGIR AJAP1 MAGED2 KCNK3 CDH2	2.51e-06	190	141	7	7e4d80a3a7f83b6a50f1d0fe82fb6c242c39d5b0
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SH3KBP1 ARHGEF25 TNFRSF21 PTGIR MAGED2 KCNK3 CDH2	2.51e-06	190	141	7	106862ef44fcaa0971c3ba0147d13eb08015ca77
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNB2 RALGPS2 GLIS3 PTGIR FRMD4A TIAM1 ROBO1	2.51e-06	190	141	7	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AFF2 TNFRSF21 PTGIR AJAP1 MAGED2 KCNK3 CDH2	2.51e-06	190	141	7	7fec459cd2ad12c2923a03d098289337c0a4c1d3
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AFF2 SH3KBP1 TNFRSF21 PTGIR MAGED2 KCNK3 CDH2	2.69e-06	192	141	7	430ef714bf2544d32f3fd96a55af010f79aa9be0
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ZNF185 ETFA PTGIR RTN2 TSC22D1 STON2 SAMD14	2.69e-06	192	141	7	f48202c271c9233c78de255a2fa131b219f688d7
ToppCell	PBMC-Severe-Hematopoietic-Platelet\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZNF185 ETFA PTGIR RTN2 TSC22D1 STON2 SAMD14	2.69e-06	192	141	7	35ae787e90e7e5e333978125e19de1590316c769
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	ARID1B NDRG1 ADAMTS18 ROBO1 NKTR SRRM2 AFF4	2.69e-06	192	141	7	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	PBMC-Severe-Hematopoietic\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZNF185 PTGIR RTN2 TSC22D1 TMCC2 STON2 SAMD14	2.69e-06	192	141	7	68d0bf6249a24d23cb1b0be434bced2ff2d0f2b4
ToppCell	PBMC-Severe-Hematopoietic\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	ZNF185 PTGIR RTN2 TSC22D1 TMCC2 STON2 SAMD14	2.69e-06	192	141	7	3b75fe82018bb259b02bfaee96b310f4d6df0350
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZNF185 ETFA PTGIR RTN2 TSC22D1 STON2 SAMD14	2.69e-06	192	141	7	3276bd4f1023a020ebb26ec33424b6e9897d31c9
ToppCell	PBMC-Severe-Hematopoietic-Platelet\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	ZNF185 ETFA PTGIR RTN2 TSC22D1 STON2 SAMD14	2.69e-06	192	141	7	9ae14279e9b91e04ea2c5bbbeadb111a1b966bd1
ToppCell	COVID-19-lung-Pericytes/_Smooth_Muscle\|lung / Disease (COVID-19 only), tissue and cell type	CACNB2 ADAMTSL1 AFF2 SPEG JPH2 ACAN KCNK3	2.89e-06	194	141	7	5e1e0513a54ec4cf0b247ec85c9fbc68dfac1da3
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HUWE1 KMT2A NKTR SRRM2 CDH2 AFF4 MAPK8IP2	2.99e-06	195	141	7	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	wk_08-11-Epithelial-PNS-TM4SF4+_PENK+_neuron\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ARPP21 TMC2 APC2 GATA3 LRFN2 REM2 MAPK8IP2	3.09e-06	196	141	7	afa3a2f5f3a51d1830c6f95f97a4b3e13ed42512
ToppCell	COVID-19-COVID-19_Severe-Others-Platelet\|COVID-19_Severe / Disease, condition lineage and cell class	ZNF185 ETFA PTGIR RTN2 TSC22D1 STON2 SAMD14	3.53e-06	200	141	7	af373636f540544addd94f51ce94ea2cb1f3ecc9
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	HIVEP2 CEP85L CCDC85A MAST4 ARHGAP29 KMT2A NOVA1	3.53e-06	200	141	7	edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCell	COVID-19-COVID-19_Severe-Others\|COVID-19_Severe / Disease, condition lineage and cell class	ZNF185 PTGIR RTN2 TSC22D1 TMCC2 STON2 SAMD14	3.53e-06	200	141	7	932b310a2838e4b354b90460fa904a8ebca4747a
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOCK3 CACNB2 SPEG JPH2 FBXL7 CDH2	1.01e-05	155	141	6	cd7d95cbcad248670e531d80bb83c55e36ebc573
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AFF2 TNFRSF21 MAGED2 KCNK3 CDH2 AGAP2	1.71e-05	170	141	6	1f994b690e881106a5d54b3080ccce6260bc3ac5
ToppCell	COVID-19-kidney-PEC\|kidney / Disease (COVID-19 only), tissue and cell type	NHSL2 CCDC85A FRMD4A FBXL7 ARHGAP29 CDH2	1.83e-05	172	141	6	36a96714a0eb6ac438648135336c9791881ddadb
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WHRN ANKS6 MSH3 FBXL7 MTHFR ACAN	1.89e-05	173	141	6	2b448acd5e584f24567204c31b8d74715e92f32a
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WHRN ANKS6 MSH3 FBXL7 MTHFR ACAN	1.89e-05	173	141	6	5086edc29c5a6137ca09877929a1317f9739c801
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOCK3 CACNB2 SPEG JPH2 FBXL7 CDH2	2.15e-05	177	141	6	b59967219f7d874805768e247c0eb2bc4d4420c8
ToppCell	LA-01._Fibroblast_I\|LA / Chamber and Cluster_Paper	GLIS3 CHD9 PTGIR FBXL7 ROBO1 NOVA1	2.29e-05	179	141	6	dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTSL1 ARPP21 TMC2 APC2 HOXA5 AP3B2	2.44e-05	181	141	6	7f99002a6411117cc2361334c7c9228e20c574b4
ToppCell	Pericytes-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	ADAMTSL1 SPEG JPH2 ARHGEF25 ACAN KCNK3	2.52e-05	182	141	6	46c213597445b1f4f09dc367f27702d24b201daf
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 JPH2 PTGIR AP3B2 KCNK3 CDH3	2.59e-05	183	141	6	0e8fb371d8eac777451c76f41d53577f5dfb740d
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 JPH2 PTGIR AP3B2 KCNK3 CDH3	2.59e-05	183	141	6	cbc3b00faa7e4e0dbbbc8ee105467c65241c7470
ToppCell	E17.5-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TRO JPH2 PTGIR MAGED2 KCNK3 CDH2	2.93e-05	187	141	6	0dee138738b65531ff134a125b92234b5d0a653c
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DOCK3 SPEG JPH2 KCNK3 CKAP4 CDH2	3.02e-05	188	141	6	c29aaae3c5bb7cd6b9b3defd4d27afde3af19ba0
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Striatum / BrainAtlas - Mouse McCarroll V32	ARPP21 TMEM121B PTPRCAP SIPA1L1 REM2 AGAP2	3.02e-05	188	141	6	e34ea7014c5a059a7db38f78bd903cf02616ddd3
ToppCell	MS-Treg-CD4_Treg\|MS / Condition, Cell_class and T cell subcluster	WHRN GATA3 PTGIR CCM2 MAST4 TNFRSF1B	3.11e-05	189	141	6	b1310eed6113b3536868340a5b2b2587ad377fa9
ToppCell	MS-Treg\|MS / Condition, Cell_class and T cell subcluster	WHRN GATA3 PTGIR CCM2 MAST4 TNFRSF1B	3.11e-05	189	141	6	3fa79242fb3dba4a3f52276da0124ba260423fb6
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	AFF2 SH3KBP1 PTGIR FRMD4A KCNK3 ADAMTS18	3.20e-05	190	141	6	10125091ad648163777b02e9f0d5e8d7f17d44a5
ToppCell	LV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	GLIS3 CHD9 PTGIR FBXL7 ROBO1 NOVA1	3.20e-05	190	141	6	12992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCell	P03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	AFF2 TNFRSF21 PTGIR MAGED2 KCNK3 CDH2	3.20e-05	190	141	6	979b1476fd2692fde977ce56257315fcfc8a01d5
ToppCell	E15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CLIP2 TNFRSF21 PTGIR MAGED2 KCNK3 CDH2	3.20e-05	190	141	6	84fbd5664ec886120963d4f50dfa1fd1851d36c1
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK3 CACNB2 SPEG JPH2 ARHGEF25 ACAN	3.30e-05	191	141	6	7853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCell	COVID-19_Severe-Hematopoietic_Mega-Platelet\|COVID-19_Severe / Disease group, lineage and cell class	ZNF185 ETFA PTGIR TSC22D1 STON2 SAMD14	3.39e-05	192	141	6	6ebdb70cc0292e41b348d38d89f77e9a3b029bd8
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK3 CACNB2 SPEG JPH2 ARHGEF25 KCNK3	3.39e-05	192	141	6	992d08092edbc68c47b945deb8708379738c239a
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	HIVEP2 CLIP2 UBR4 SREBF2 GLIS3 AFF4	3.39e-05	192	141	6	6bba80887d6f64cf913a5c22f62baaddda417ce0
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNB2 GLIS3 PTGIR FRMD4A TIAM1 ROBO1	3.39e-05	192	141	6	df1545670370fb1010c567cd059c2783eab315f7
ToppCell	Pericytes\|World / lung cells shred on cell class, cell subclass, sample id	SPEG JPH2 ARHGEF25 PTGIR ACAN KCNK3	3.39e-05	192	141	6	057ad22b878c0c5fb59ed1412ca13db945c57a5a
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AFF2 TRO SPEG JPH2 KCNK3 CDH2	3.39e-05	192	141	6	2cc712186e37fb21a964c032765c36a8b4a852cf
ToppCell	P03-Mesenchymal-developing_mesenchymal_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	AFF2 TNFRSF21 PTGIR MAGED2 KCNK3 CDH2	3.39e-05	192	141	6	063e119c4b58957643908f667e6cfd6f7517fd03
ToppCell	COVID-19_Severe-Hematopoietic_Mega\|COVID-19_Severe / Disease group, lineage and cell class	ZNF185 ETFA PTGIR TSC22D1 STON2 SAMD14	3.39e-05	192	141	6	2764c3c68982077a448ff5da58344e0f6cec0a52
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-Pericytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SCHIP1 JPH2 ARHGEF25 PTGIR ACAN KCNK3	3.49e-05	193	141	6	7631bf3362b4fa061ffeab4879ab12c4708dc4c0
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	DOCK3 CACNB2 JPH2 MAST4 IQCJ-SCHIP1 CDH2	3.49e-05	193	141	6	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RALGPS2 ARHGEF38 GLIS3 AJAP1 ARHGAP29 CDH3	3.49e-05	193	141	6	263d185af6ed80e639f864e4966268e0862c61dc
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SCHIP1 JPH2 ARHGEF25 PTGIR ACAN KCNK3	3.49e-05	193	141	6	8d15c63f2ae48d0a00d7ef5fdafa917ab8ad0571
ToppCell	LA-14._Fibroblast_III\|LA / Chamber and Cluster_Paper	HIVEP2 GLIS3 ARID1B FBXL7 TIAM1 NOVA1	3.49e-05	193	141	6	7426c291bac59e539c427bcaae18abc7d397d44e
ToppCell	LV-01._Fibroblast_I\|LV / Chamber and Cluster_Paper	GLIS3 CHD9 PTGIR FBXL7 ROBO1 NOVA1	3.49e-05	193	141	6	dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ARPP21 TMC2 APC2 HOXA5 AP3B2 MAPK8IP2	3.60e-05	194	141	6	15224fb3e7ca5bd1fb8c41f8275842f737014095
ToppCell	10x5'-blood-Hematopoietic_Erythro-Mega-Megakaryocyte_early\|blood / Manually curated celltypes from each tissue	ZNF185 ETFA PTGIR TSC22D1 STON2 SAMD14	3.60e-05	194	141	6	63dea7d630962761a70aa88e720ee35c22cbc81a
ToppCell	10x5'-blood-Hematopoietic_Erythro-Mega\|blood / Manually curated celltypes from each tissue	ZNF185 ETFA PTGIR TSC22D1 STON2 SAMD14	3.60e-05	194	141	6	d0e7d35b5086834929c4bd39d4c6719b2d5fc71e
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AFF2 TNFRSF21 TSC22D1 MAGED2 KCNK3 CDH2	3.70e-05	195	141	6	4a5d2f62aad5817d077177bf8b4ff0e46d3b8d97
ToppCell	E17.5-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CACNB2 ARHGEF25 TSC22D1 KCNK3 ROBO1 CDH4	3.70e-05	195	141	6	1daddd801bd4596fffbdb822fc326d5127c96004
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AFF2 TNFRSF21 TSC22D1 MAGED2 KCNK3 CDH2	3.70e-05	195	141	6	7a32a8535c29b819dacba901d0658280a2631c94
ToppCell	E17.5-Mesenchymal-myocytic_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CACNB2 ARHGEF25 TSC22D1 MAGED2 KCNK3 CDH4	3.70e-05	195	141	6	01a750d660993017af00736215cbcff2de5909c1
ToppCell	RA-02._Fibroblast_II\|RA / Chamber and Cluster_Paper	GLIS3 CHD9 ARID1B FBXL7 TIAM1 ROBO1	3.70e-05	195	141	6	6a02ebbeb3199447ddce64d92d8809436e040eba
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gabrg1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	WHRN KCNK3 SP9 TNFRSF1B INPP5J	3.71e-05	118	141	5	3f0a304ef9c9e5ba047fc09f4372590eed624328
ToppCell	CV-Moderate-6\|CV / Virus stimulation, Condition and Cluster	HUWE1 MAGED2 KMT2A APPL1 SRRM2 AFF4	3.81e-05	196	141	6	7bced0cc2112697593c478fa291b8ed3941fb811
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	AFF2 JPH2 ARHGEF25 AJAP1 IQCJ-SCHIP1 CDH3	3.81e-05	196	141	6	a58bdf9de05d13d84211e09a933679d485bf8ab4
ToppCell	NS-critical-d_16-33-Lymphoid-Treg\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CEP85L GATA3 TNRC6C PTPRCAP TIAM1 KMT2A	3.81e-05	196	141	6	ad2d17cbfa1af4142f9cec2ea1a37d11d4b4151a
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTSL1 ARPP21 APC2 HOXA5 AP3B2 MAPK8IP2	3.92e-05	197	141	6	5593721407f61fc5bc3f2f8bf8fa2604c4e29565
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGEF25 TSC22D1 MAGED2 KCNK3 CDH2 CDH4	3.92e-05	197	141	6	e132f4b9deef6a565262c0aa0863cafe28f248e6
ToppCell	Bronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CACNB2 SPEG JPH2 MSH4 ARHGEF25 ACAN	3.92e-05	197	141	6	d1cb30ec4f3024541e9876c70bf63fe4d5c55bf1
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK3 CACNB2 SPEG JPH2 KCNK3 IQCJ-SCHIP1	3.92e-05	197	141	6	ac4f53acb2f8a428b0f2fab3c30a34e095a1bed7
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADAMTSL1 ARHGEF38 SREBF2 MAST4 NDRG1 FAM13A	4.03e-05	198	141	6	5fc25b008a4d8d6bec83923a16f64dd9e1ff1f2d
ToppCell	Tracheal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CACNB2 ARPP21 SPEG JPH2 MTHFR KCNK3	4.03e-05	198	141	6	cbb63b255bdc92a557c5db1f08f7766ed9346607
ToppCell	IPF-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	ADAMTSL1 MAST4 NDRG1 ADAMTS18 ROBO1 IQCJ-SCHIP1	4.03e-05	198	141	6	b8bd1ba268480f54451648e01631b615a3401144
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK3 CACNB2 SPEG JPH2 KCNK3 IQCJ-SCHIP1	4.03e-05	198	141	6	22e766df1276c5b14aa0d83f434f47140ebb98ea
Drug	0317956-0000 [391210-11-0]; Down 200; 10uM; MCF7; HT_HG-U133A	SOWAHC TNFRSF21 CIC SIGLEC7 PTPRCAP TIAM1 ACAN INPP5J MAPK8IP2	2.73e-06	191	139	9	3855_DN
Drug	Trioxsalen [3902-71-4]; Up 200; 17.6uM; HL60; HT_HG-U133A	DSG3 TRO HUWE1 MTHFR ACAN RAB11FIP5 SAMD14 ARHGAP33 MAPK8IP2	3.52e-06	197	139	9	2516_UP
Drug	Ungerine nitrate; Up 200; 10.2uM; HL60; HT_HG-U133A	LZTS3 ZNF362 TNFRSF21 KRT24 SIGLEC7 RAB11FIP5 ARHGAP33 MAPK8IP2 AGAP2	3.82e-06	199	139	9	2514_UP
Drug	Tribenoside [10310-32-4]; Up 200; 8.4uM; HL60; HT_HG-U133A	SREBF2 SMG5 TSC22D1 SIGLEC7 FAM13A MTHFR UBTF SIPA1L1	1.79e-05	184	139	8	2946_UP
Drug	Danazol [17230-88-5]; Down 200; 11.8uM; HL60; HG-U133A	HIPK1 TNFRSF21 GTF2F1 NDRG1 PTPRCAP CTDP1 NKTR SNAPC4	2.34e-05	191	139	8	2038_DN
Drug	Methylhydantoin-5-(L) [40856-73-3]; Down 200; 35uM; MCF7; HT_HG-U133A	WHRN LZTS3 CIC STIM1 MAST4 AJAP1 PTPRCAP AFF4	2.52e-05	193	139	8	3378_DN
Drug	0173570-0000 [211245-44-2]; Up 200; 10uM; MCF7; HT_HG-U133A	WHRN LZTS3 DSG3 TNFRSF21 PTGIR FRMD4A NKTR CDH2	2.52e-05	193	139	8	4712_UP
Drug	Karakoline [39089-30-0]; Down 200; 10.6uM; MCF7; HT_HG-U133A	AFF2 RALGPS2 SMG5 MTHFR NKTR ARHGAP33 CAPN15 AGAP2	2.61e-05	194	139	8	4763_DN
Drug	Hesperidin [520-26-3]; Down 200; 6.6uM; MCF7; HT_HG-U133A	ZSWIM8 MARCHF7 GTF2F1 MAST4 TIAM1 KMT2A ROBO1 SNAPC4	2.71e-05	195	139	8	5313_DN
Drug	Estropipate [7280-37-7]; Up 200; 9.2uM; MCF7; HT_HG-U133A	CIC FBXL7 SIGLEC7 AJAP1 PER3 ACAN ARHGAP33 CAPN15	2.71e-05	195	139	8	6808_UP
Drug	Oxymetazoline hydrochloride [2315-02-8]; Down 200; 13.4uM; HL60; HG-U133A	MARCHF7 CHD9 MSH3 ERBIN SIGLEC7 UBTF ACAN CKAP4	2.71e-05	195	139	8	1431_DN
Drug	Propafenone hydrochloride [34183-22-7]; Up 200; 10.6uM; MCF7; HT_HG-U133A	WHRN SPEG RALGPS2 SIGLEC7 INPP5J ARHGAP33 MAPK8IP2 AGAP2	2.81e-05	196	139	8	2871_UP
Drug	Racecadotril [81110-73-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A	TRO RALGPS2 RTN2 CIC FRMD4A PER3 TMCC2 CAPN15	2.81e-05	196	139	8	2774_UP
Drug	Ethambutol dihydrochloride [1070-11-7]; Up 200; 14.4uM; MCF7; HT_HG-U133A	DOCK3 WHRN SPEG FRMD4A KRT24 AJAP1 AP3B2 AFF4	2.92e-05	197	139	8	4120_UP
Drug	Ramipril [87333-19-5]; Up 200; 9.6uM; MCF7; HT_HG-U133A	CACNB2 CLIP2 FBXL7 PER3 MTHFR ACAN TMCC2 NKTR	2.92e-05	197	139	8	6792_UP
Drug	Lomefloxacin hydrochloride [98079-52-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A	WHRN AFF2 MARCHF7 STIM1 MAST4 PER3 MTHFR INPP5J	2.92e-05	197	139	8	4745_DN
Drug	Tadjakonine [11087-94-8]; Down 200; 7.4uM; HL60; HT_HG-U133A	SETD1A ZNF185 SMG5 HOXA5 MAGED2 CCDC106 CKAP4 SRRM2	3.13e-05	199	139	8	2165_DN
Drug	DAPH; Up 200; 10uM; PC3; HG-U133A	SMG5 CIC MAST4 FAM13A MAGED2 CTDP1 CDH3 MAPK8IP2	3.13e-05	199	139	8	578_UP
Drug	Tiaprofenic acid [33005-95-7]; Up 200; 15.4uM; PC3; HT_HG-U133A	PTGIR KANSL3 FRMD4A KRT24 MTHFR ACAN AFF4 AGAP2	3.25e-05	200	139	8	4091_UP
Drug	Austricine [10180-88-8]; Down 200; 14.2uM; HL60; HT_HG-U133A	AFF2 LZTS3 ZNF185 SIGLEC7 PER3 MAGED2 RAB11FIP5 CCDC106	3.25e-05	200	139	8	2157_DN
Drug	Dobutamine hydrochloride [49745-95-1]; Up 200; 11.8uM; PC3; HT_HG-U133A	WHRN SMG5 HUWE1 MAST4 TIAM1 SNAPC4 AFF4	1.44e-04	185	139	7	6286_UP
Drug	Mebendazole [31431-39-7]; Up 200; 13.6uM; MCF7; HT_HG-U133A	WHRN RALGPS2 ARHGEF38 TNFRSF21 PTPRCAP SIPA1L1 AGAP2	1.65e-04	189	139	7	2300_UP
Drug	MS-275; Down 200; 10uM; PC3; HT_HG-U133A	LZTS3 SMG5 GTF2F1 UBTF KMT2A UNKL SRRM2	1.65e-04	189	139	7	7074_DN
Drug	Dicumarol [66-76-2]; Up 200; 11.8uM; MCF7; HT_HG-U133A	WHRN SETD1A CACNB2 HIPK1 TMCC2 KMT2A AFF4	1.70e-04	190	139	7	3848_UP
Drug	Methapyrilene hydrochloride [135-23-9]; Down 200; 13.4uM; PC3; HT_HG-U133A	WHRN HIPK1 GTF2F1 MAST4 FAM13A KMT2A KDM4A	1.76e-04	191	139	7	6644_DN
Drug	Rilmenidine hemifumarate [54187-04-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A	WHRN CBARP NUP214 ZNF362 ACAN CTDP1 AGAP2	1.82e-04	192	139	7	6512_UP
Drug	rosiglitazone; Up 200; 10uM; HL60; HT_HG-U133A	UBR4 TNFRSF21 FBXL7 SIGLEC7 MTHFR SIPA1L1 ARHGAP33	1.82e-04	192	139	7	1174_UP
Drug	Decamethonium bromide [541-22-0]; Up 200; 9.6uM; HL60; HT_HG-U133A	DSG3 ZNF185 ARHGEF38 ZNF362 FAM13A MTHFR TMCC2	1.88e-04	193	139	7	2933_UP
Drug	Heliotrine [303-33-3]; Down 200; 12.8uM; PC3; HT_HG-U133A	WHRN RALGPS2 GATA3 MAST4 CCDC106 ARHGAP33 CAPN15	1.94e-04	194	139	7	3717_DN
Drug	Hydralazine hydrochloride [304-20-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A	SHANK1 LZTS3 TRO SPEG RALGPS2 ARHGEF38 PLCB2	1.94e-04	194	139	7	2311_UP
Drug	ICI182,780; Down 200; 1uM; MCF7; HT_HG-U133A	SETD1A TRO HUWE1 TNFRSF21 FRMD4A FBXL7 SIPA1L1	1.94e-04	194	139	7	7534_DN
Drug	15d-PGJ2; Down 200; 10uM; PC3; HT_HG-U133A	WHRN SETD1A HIVEP2 CTDP1 PLCB2 INPP5J ARHGAP33	1.94e-04	194	139	7	4455_DN
Drug	Flutamide [13311-84-7]; Down 200; 14.4uM; MCF7; HT_HG-U133A	HIPK1 FRMD4A KMT2A KDM4A NKTR SRRM2 AGAP2	1.94e-04	194	139	7	4361_DN
Drug	Amyleine hydrochloride [532-59-2]; Down 200; 14.8uM; MCF7; HT_HG-U133A	WHRN SMG5 FRMD4A FBXL7 INPP5J ARHGAP33 CAPN15	1.94e-04	194	139	7	4169_DN
Drug	Moricizine hydrochloride [31883-05-3]; Up 200; 8.6uM; HL60; HT_HG-U133A	UBR4 SIGLEC7 FAM13A MAGED2 UBTF ARHGAP33 AGAP2	1.94e-04	194	139	7	2959_UP
Drug	Methyl benzethonium chloride [25155-18-4]; Down 200; 8.6uM; PC3; HT_HG-U133A	SETD1A ARHGEF38 UBTF CTDP1 CCDC106 ARHGAP33 CAPN15	1.94e-04	194	139	7	4325_DN
Drug	9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2; Up 200; 10uM; PC3; HT_HG-U133A	LZTS3 SREBF2 SOWAHC RTN2 TSC22D1 SNAPC4 CAPN15	2.00e-04	195	139	7	7557_UP
Drug	Nefopam hydrochloride [23327-57-3]; Up 200; 13.8uM; MCF7; HT_HG-U133A	SPEG APC2 RALGPS2 RTN2 KRT24 SIGLEC7 AFF4	2.00e-04	195	139	7	2317_UP
Drug	Amphotericin B [1397-89-3]; Up 200; 4.4uM; PC3; HT_HG-U133A	AFF2 TRO RTN2 MTHFR ACAN ARHGAP33 NOVA1	2.00e-04	195	139	7	6303_UP
Drug	Tenoxicam [59804-37-4]; Up 200; 11.8uM; HL60; HT_HG-U133A	AFF2 ZNF185 FBXL7 SIGLEC7 FAM13A RAB11FIP5 SRRM2	2.00e-04	195	139	7	2501_UP
Drug	2-propylpentanoic acid; Up 200; 50uM; MCF7; HT_HG-U133A	SPEG FRMD4A PTPRCAP ACAN KMT2A PLCB2 NOVA1	2.00e-04	195	139	7	5582_UP
Drug	Cefmetazole sodium salt [56796-39-5]; Down 200; 8.2uM; PC3; HT_HG-U133A	SREBF2 MARCHF7 NUP214 MSH3 UBTF KMT2A KDM4A	2.06e-04	196	139	7	5868_DN
Drug	Clomipramine hydrochloride [17321-77-6]; Up 200; 11.4uM; HL60; HG-U133A	ZNF185 RTN2 SIGLEC7 FAM13A ACAN KDM4A ARHGAP33	2.06e-04	196	139	7	1566_UP
Drug	Epicatechin-(-) [154-23-4]; Down 200; 13.8uM; PC3; HT_HG-U133A	CACNB2 CLIP2 SPEG GATA3 MAST4 UBTF ARHGAP33	2.06e-04	196	139	7	4594_DN
Drug	Erythromycin [114-07-8]; Up 200; 5.4uM; HL60; HG-U133A	ZNF185 NUP214 TNFRSF21 NFE2L1 UBTF ACAN ARHGAP33	2.06e-04	196	139	7	2010_UP
Drug	Parbendazole [14255-87-9]; Up 200; 16.2uM; MCF7; HT_HG-U133A	ZSWIM8 SPEG UBR4 CBARP HUWE1 PTPRCAP ACAN	2.06e-04	196	139	7	4357_UP
Drug	Iohexol [66108-95-0]; Down 200; 4.8uM; PC3; HT_HG-U133A	TRO TIAM1 CCDC106 SNAPC4 SRRM2 MAPK8IP2 NOVA1	2.06e-04	196	139	7	4643_DN
Drug	Quinidine hydrochloride monohydrate [6151-40-2]; Up 200; 10.6uM; PC3; HT_HG-U133A	AFF2 SREBF2 HUWE1 FRMD4A SIGLEC7 ACAN KMT2A	2.06e-04	196	139	7	5793_UP
Drug	Morantel tartrate [26155-31-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A	SMG5 SOWAHC MAST4 AJAP1 KMT2A KDM4A SNAPC4	2.06e-04	196	139	7	7010_UP
Drug	Etomidate [33125-97-2]; Up 200; 16.4uM; HL60; HT_HG-U133A	UBR4 FRMD4A MAGED2 UBTF RAB11FIP5 CCDC106 AGAP2	2.06e-04	196	139	7	2958_UP
Drug	Gliclazide [21187-98-4]; Up 200; 12.4uM; HL60; HG-U133A	LZTS3 NUP214 TNFRSF21 ACAN CTDP1 PLCB2 ARHGAP33	2.06e-04	196	139	7	1720_UP
Drug	Tetracaone hydrochloride [136-47-0]; Up 200; 13.2uM; MCF7; HT_HG-U133A	RTN2 STIM1 FRMD4A SIGLEC7 NDRG1 SIPA1L1 MAPK8IP2	2.13e-04	197	139	7	2888_UP
Drug	ICI 182,780; Up 200; 1uM; MCF7; HT_HG-U133A	WHRN ARHGEF38 ZNF362 KRT24 TMCC2 PLCB2 AGAP2	2.13e-04	197	139	7	5565_UP
Drug	Azapropazone [13539-59-8]; Up 200; 13.4uM; HL60; HT_HG-U133A	ZSWIM8 MSH4 FBXL7 SIGLEC7 MTHFR AFF4 AGAP2	2.13e-04	197	139	7	3143_UP
Drug	PNU-0251126 [267429-19-6]; Up 200; 10uM; PC3; HT_HG-U133A	WHRN LZTS3 NUP214 FBXL7 PER3 FAM13A MTHFR	2.13e-04	197	139	7	7388_UP
Drug	Idazoxan hydrochloride [79944-56-2]; Down 200; 16.6uM; PC3; HT_HG-U133A	WHRN ARHGEF38 FBXL7 TIAM1 NKTR NOVA1 CAPN15	2.13e-04	197	139	7	6747_DN
Drug	Griseofulvin [126-07-8]; Up 200; 11.2uM; PC3; HT_HG-U133A	SHANK1 MSH3 CIC KRT24 AJAP1 MTHFR AFF4	2.13e-04	197	139	7	3664_UP
Drug	LY 294002; Up 200; 10uM; HL60; HT_HG-U133A	ZSWIM8 HIVEP2 NUP214 MSH3 RTN2 MAGED2 SIPA1L1	2.13e-04	197	139	7	6198_UP
Drug	Esculetin [305-01-1]; Up 200; 22.4uM; HL60; HT_HG-U133A	ZSWIM8 CACNB2 LZTS3 SIGLEC7 ACAN TMCC2 ARHGAP33	2.13e-04	197	139	7	3120_UP
Drug	Colistin sulfate [1264-72-8]; Down 200; 3uM; PC3; HT_HG-U133A	WHRN KANSL3 FBXL7 TIAM1 SNAPC4 AFF4 NOVA1	2.13e-04	197	139	7	4212_DN
Drug	Ajmaline [4360-12-7]; Up 200; 12.2uM; HL60; HG-U133A	MYF6 NUP214 MSH3 SIGLEC7 ACAN TMCC2 SAMD14	2.13e-04	197	139	7	1749_UP
Drug	Levonordefrin [829-74-3]; Down 200; 21.8uM; MCF7; HT_HG-U133A	NUP214 MAST4 UBTF SIPA1L1 NKTR SRRM2 CAPN15	2.13e-04	197	139	7	7208_DN
Drug	Sulfabenzamide [127-71-9]; Up 200; 14.4uM; MCF7; HT_HG-U133A	CACNB2 NUP214 HUWE1 MAST4 AJAP1 INPP5J ARHGAP33	2.13e-04	197	139	7	4979_UP
Drug	Niridazole [61-57-4]; Down 200; 18.6uM; MCF7; HT_HG-U133A	SETD1A SMG5 MSH3 SOWAHC TNFRSF21 MAST4 RAB11FIP5	2.13e-04	197	139	7	3301_DN
Drug	chlorpropamide; Up 200; 100uM; MCF7; HG-U133A	AFF2 ZNF185 SREBF2 TNFRSF21 CIC NKTR AGAP2	2.13e-04	197	139	7	141_UP
Drug	Dapsone [80-08-0]; Down 200; 16.2uM; MCF7; HT_HG-U133A	WHRN SETD1A LZTS3 CIC STIM1 MAST4 SRRM2	2.13e-04	197	139	7	1705_DN
Drug	Cefotiam hydrochloride; Up 200; 7.2uM; MCF7; HT_HG-U133A	WHRN ZSWIM8 SPEG NUP214 KRT24 SIGLEC7 CDH2	2.13e-04	197	139	7	3319_UP
Drug	Dicloxacillin sodium salt [13412-64-1]; Up 200; 8.2uM; MCF7; HT_HG-U133A	WHRN SPEG RALGPS2 SREBF2 KRT24 PTPRCAP AGAP2	2.13e-04	197	139	7	3307_UP
Drug	Pyridoxine hydrochloride [58-56-0]; Down 200; 19.4uM; MCF7; HT_HG-U133A	SMG5 CIC GTF2F1 APPL1 SNAPC4 SRRM2 CAPN15	2.13e-04	197	139	7	7171_DN
Drug	Amikacin hydrate [37517-28-5]; Up 200; 6.6uM; MCF7; HT_HG-U133A	SETD1A SREBF2 NUP214 FRMD4A RAB11FIP5 ROBO1 SNAPC4	2.13e-04	197	139	7	5314_UP
Drug	Cefixime [79350-37-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A	WHRN SETD1A CIC NDRG1 NKTR SRRM2 ARHGAP33	2.13e-04	197	139	7	3247_UP
Drug	Pseudopelletierine hydrochloride [6164-62-1]; Up 200; 21uM; MCF7; HT_HG-U133A	SETD1A ZNF362 CIC UNKL SRRM2 INPP5J ARHGAP33	2.13e-04	197	139	7	2766_UP
Drug	Bromopride [4093-35-0]; Up 200; 11.6uM; MCF7; HT_HG-U133A	WHRN ARHGEF38 KRT24 FBXL7 NKTR CDH2 NOVA1	2.19e-04	198	139	7	6037_UP
Drug	trifluoperazine dihydrochloride; Down 200; 10uM; PC3; HT_HG-U133A	PER3 FAM13A CCDC106 PLCB2 SNAPC4 SRRM2 INPP5J	2.19e-04	198	139	7	4448_DN
Drug	Deltaline [6836-11-9]; Up 200; 7.8uM; MCF7; HT_HG-U133A	CACNB2 ARHGEF38 HUWE1 RTN2 ACAN KMT2A CDH2	2.19e-04	198	139	7	6026_UP
Drug	Thioperamide maleate [106243-16-7]; Up 200; 9.8uM; PC3; HT_HG-U133A	SETD1A RALGPS2 HUWE1 KANSL3 PTPRCAP PER3 ACAN	2.19e-04	198	139	7	4675_UP
Drug	Flufenamic acid [530-78-9]; Up 200; 14.2uM; PC3; HT_HG-U133A	TRO APC2 ARHGEF38 KRT24 MTHFR ACAN AGAP2	2.19e-04	198	139	7	5059_UP
Drug	Amoxapine [14028-44-5]; Down 200; 12.8uM; MCF7; HT_HG-U133A	SETD1A SMG5 UBTF TMCC2 SNAPC4 INPP5J CAPN15	2.19e-04	198	139	7	1513_DN
Drug	Isocorydine (+) [475-67-2]; Up 200; 11.8uM; HL60; HG-U133A	ARHGEF38 SMG5 MSH3 TNFRSF21 MAGED2 ACAN SNAPC4	2.19e-04	198	139	7	1787_UP
Drug	Seneciphylline [480-81-9]; Up 200; 12uM; MCF7; HT_HG-U133A	RALGPS2 CIC SIGLEC7 NDRG1 MTHFR CTDP1 CAPN15	2.19e-04	198	139	7	2797_UP
Drug	Chlorogenic acid [327-97-9]; Up 200; 11.2uM; MCF7; HT_HG-U133A	WHRN RALGPS2 PER3 KMT2A UNKL NOVA1 CAPN15	2.19e-04	198	139	7	4142_UP
Drug	Mephenesin [59-47-2]; Up 200; 22uM; MCF7; HT_HG-U133A	DOCK3 LZTS3 CLIP2 ARHGEF38 KRT24 PTPRCAP ACAN	2.19e-04	198	139	7	2304_UP
Drug	Verapamyl hydrochloride [152-11-4]; Up 200; 8.2uM; MCF7; HT_HG-U133A	LZTS3 ZNF362 FBXL7 MAST4 TMCC2 RAB11FIP5 KMT2A	2.19e-04	198	139	7	5387_UP
Drug	Oxprenolol hydrochloride [6452-73-9]; Up 200; 13.2uM; HL60; HT_HG-U133A	SHANK1 ARHGEF38 MSH4 AJAP1 PER3 ACAN SAMD14	2.19e-04	198	139	7	6145_UP
Drug	AC1L7GLZ	DSG3 NUP214	2.20e-04	4	139	2	CID000360406
Drug	Flunixin meglumine [42461-84-7]; Up 200; 8.2uM; MCF7; HT_HG-U133A	SPEG FBXL7 AJAP1 PTPRCAP MTHFR RAB11FIP5 CCDC106	2.26e-04	199	139	7	4735_UP
Drug	Edrophonium chloride [116-38-1]; Down 200; 19.8uM; PC3; HT_HG-U133A	WHRN GATA3 SMG5 MAST4 FAM13A AFF4 ARHGAP33	2.26e-04	199	139	7	6655_DN
Drug	Alfuzosin hydrochloride [81403-68-1]; Down 200; 9.4uM; MCF7; HT_HG-U133A	WHRN ZSWIM8 LZTS3 SMG5 TNFRSF21 CTDP1 SRRM2	2.26e-04	199	139	7	3203_DN
Drug	Metaraminol bitartrate [33402-03-8]; Up 200; 8.6uM; MCF7; HT_HG-U133A	RALGPS2 RTN2 FBXL7 SIPA1L1 TMCC2 INPP5J MAPK8IP2	2.26e-04	199	139	7	2298_UP
Drug	Vincamine [1617-90-9]; Up 200; 11.2uM; HL60; HT_HG-U133A	TRO SIGLEC7 PER3 MAGED2 SIPA1L1 PLCB2 CKAP4	2.26e-04	199	139	7	2367_UP
Drug	Isosorbide dinitrate [87-33-2]; Up 200; 17uM; MCF7; HT_HG-U133A	ZSWIM8 CACNB2 AFF2 TRO FBXL7 AJAP1 MTHFR	2.33e-04	200	139	7	6038_UP
Drug	Iohexol [66108-95-0]; Up 200; 4.8uM; MCF7; HT_HG-U133A	WHRN ZSWIM8 CIC KRT24 PER3 SRRM2 CAPN15	2.33e-04	200	139	7	3322_UP
Drug	Hesperidin [520-26-3]; Up 200; 6.6uM; MCF7; HT_HG-U133A	CACNB2 LZTS3 RTN2 KRT24 ACAN AP3B2 ARHGAP33	2.33e-04	200	139	7	2648_UP
Disease	Malignant neoplasm of breast	CEP85L UBR4 APC2 ARHGEF38 GATA3 SREBF2 NUP214 CIC ARID1B NDRG1 PER3 MAGED2 MTHFR SIPA1L1 ARHGAP29 ROBO1 APPL1 CDH2 AGAP2	4.70e-07	1074	135	19	C0006142
Disease	chronic obstructive pulmonary disease	SETD1A ADAMTSL1 HIVEP2 SPEG RALGPS2 ARHGEF38 GLIS3 ZNF362 NUP42 FRMD4A FAM13A AEBP2 DOT1L NOVA1	3.50e-06	688	135	14	EFO_0000341
Disease	systolic blood pressure, alcohol consumption measurement	CACNB2 MTHFR RP1L1 KCNK3	6.42e-05	47	135	4	EFO_0006335, EFO_0007878
Disease	Nystagmus	AFF2 MSH3 MAST4	1.17e-04	21	135	3	HP_0000639
Disease	response to calcium channel blocker	DOCK3 MUC19 TIAM1 KCNK3	1.28e-04	56	135	4	EFO_0007767
Disease	QRS-T angle	ADAMTSL1 CEP85L SPEG SIPA1L1 KMT2A	1.30e-04	106	135	5	EFO_0020097
Disease	C-reactive protein measurement	DOCK3 ZSWIM8 CACNB2 ARPP21 ETFA ISL2 DGKZ LRFN2 TMCC2 RP1L1 KCNK3 SP9 SNAPC4 CDH4 AFF4 ARHGAP33	1.31e-04	1206	135	16	EFO_0004458
Disease	aspartate aminotransferase measurement	WHRN CACNB2 WWC3 ETFA MUC19 MARCHF7 NUP214 KRT79 FAM13A NFE2L1 TMCC2 ARHGAP29 ROBO1	2.70e-04	904	135	13	EFO_0004736
Disease	neuroimaging measurement, brain volume measurement	CACNB2 GLIS3 FBXL7 MAST4 TMCC2 ROBO1 IQCJ-SCHIP1	3.60e-04	286	135	7	EFO_0004346, EFO_0006930
Disease	mean arterial pressure, unipolar depression	CACNB2 MTHFR KCNK3	4.22e-04	32	135	3	EFO_0003761, EFO_0006340
Disease	Developmental regression	NUP214 UBTF	4.30e-04	7	135	2	C1836830
Disease	CHARGE syndrome (implicated_via_orthology)	CHD9 CHD2	4.30e-04	7	135	2	DOID:0050834 (implicated_via_orthology)
Disease	myoclonic-atonic epilepsy (implicated_via_orthology)	CHD2 ROBO1	4.30e-04	7	135	2	DOID:0060475 (implicated_via_orthology)
Disease	Abnormality of the eye	APC2 CDH2	4.30e-04	7	135	2	C4316870
Disease	vital capacity	ADAMTSL1 HIVEP2 DOK7 RALGPS2 GLIS3 JPH2 HOXA5 SENP1 FAM13A ACAN ADAMTS18 EIF3H DOT1L SNAPC4 CDH2	5.50e-04	1236	135	15	EFO_0004312
Disease	autism spectrum disorder (implicated_via_orthology)	SHANK1 CHD9 CHD2 ARID1B LRFN2	6.88e-04	152	135	5	DOID:0060041 (implicated_via_orthology)
Disease	prostate cancer (is_marker_for)	SREBF2 KMT2A KDM4A EIF3H AGAP2	7.73e-04	156	135	5	DOID:10283 (is_marker_for)
Disease	smoking status measurement, systolic blood pressure	CACNB2 ADAMTSL1 AJAP1 MTHFR KCNK3	7.73e-04	156	135	5	EFO_0006335, EFO_0006527
Disease	diverticular disease	DOCK3 CACNB2 ETFA KCNK3 ROBO1 IQCJ-SCHIP1	7.82e-04	236	135	6	EFO_0009959
Disease	smoking status measurement, diastolic blood pressure	CACNB2 ADAMTSL1 ARID1B MTHFR KCNK3	8.42e-04	159	135	5	EFO_0006336, EFO_0006527
Disease	cholesteryl ester 20:5 measurement	DOK7 CKAP4 CDH2	1.08e-03	44	135	3	EFO_0010349
Disease	polymyositis (is_marker_for)	ROBO1 TNFRSF1B	1.11e-03	11	135	2	DOID:0080745 (is_marker_for)
Disease	corpus callosum volume measurement	SCHIP1 CCM2 FBXL7 IQCJ-SCHIP1	1.17e-03	100	135	4	EFO_0010299
Disease	selective IgA deficiency disease	GATA3 DGKZ MAST4	1.23e-03	46	135	3	EFO_1001929
Disease	dimethylglycine measurement	ADAMTSL1 ETFA ISL2	1.23e-03	46	135	3	EFO_0010476
Disease	Diverticular Bleeding	ETFA ISL2	1.57e-03	13	135	2	C4505353
Disease	Diverticular Diseases	ETFA ISL2	1.57e-03	13	135	2	C4317009
Disease	L2 Acute Lymphoblastic Leukemia	NUP214 MTHFR KMT2A	1.57e-03	50	135	3	C0023453
Disease	cognitive inhibition measurement	CACNB2 HIVEP2 MUC22	1.57e-03	50	135	3	EFO_0007969
Disease	mean arterial pressure, alcohol consumption measurement	MTHFR RP1L1 KCNK3	1.76e-03	52	135	3	EFO_0006340, EFO_0007878
Disease	Childhood Acute Lymphoblastic Leukemia	NUP214 MTHFR KMT2A	1.76e-03	52	135	3	C0023452
Disease	Myopathy, Centronuclear, Autosomal Dominant	MYF6 STIM1	1.82e-03	14	135	2	C1834558
Disease	lobe size	HIVEP2 SOWAHC	1.82e-03	14	135	2	EFO_0007666
Disease	colonic neoplasm, overall survival	AFF2 DSG3	1.82e-03	14	135	2	EFO_0000638, EFO_0004288
Disease	cortical thickness	RALGPS2 GLIS3 MSH3 ARID1B FBXL7 MAST4 MTHFR UBTF KCNK3 ADAMTS18 KMT2A ROBO1 IQCJ-SCHIP1	1.83e-03	1113	135	13	EFO_0004840
Disease	Mouth Neoplasms	HOXA5 NDRG1 TIAM1	1.96e-03	54	135	3	C0026640
Disease	Malignant neoplasm of mouth	HOXA5 NDRG1 TIAM1	1.96e-03	54	135	3	C0153381
Disease	Replication Error Phenotype	MSH3 MTHFR	2.10e-03	15	135	2	C1721098
Disease	cis/trans-18:2 fatty acid measurement, trans fatty acid measurement	DOK7 CDH4	2.10e-03	15	135	2	EFO_0006821, EFO_0006824
Disease	Microsatellite Instability	MSH3 MTHFR	2.10e-03	15	135	2	C0920269
Disease	Autosomal Recessive Centronuclear Myopathy	SPEG STIM1	2.10e-03	15	135	2	C3645536
Disease	polyp of colon	DOK7 EIF3H CDH3	2.17e-03	56	135	3	MONDO_0021400
Disease	Cardiovascular Abnormalities	ANKS6 APC2	2.39e-03	16	135	2	C0243050
Disease	Astrocytosis	TNFRSF21 KCNK3	2.70e-03	17	135	2	C3887640
Disease	glutarylcarnitine (C5-DC) measurement	ETFA ISL2	2.70e-03	17	135	2	EFO_0800030
Disease	Gliosis	TNFRSF21 KCNK3	2.70e-03	17	135	2	C0017639
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	NUP214 MTHFR KMT2A	2.78e-03	61	135	3	C1961102
Disease	response to bronchodilator, FEV/FEC ratio	ARHGEF38 LRFN2 FBXL7 MAST4 FAM13A SIPA1L1 RP1L1 KCNK3 IQCJ-SCHIP1 CDH2	2.82e-03	766	135	10	EFO_0004713, GO_0097366
Disease	hypertension	CACNB2 TIAM1 MTHFR KCNK3 PLCB2 KDM4A	2.96e-03	307	135	6	EFO_0000537
Disease	Calcium channel blocker use measurement	CACNB2 GLIS3 JPH2 MTHFR KCNK3	3.04e-03	213	135	5	EFO_0009930
Disease	white matter integrity	FBXL7 TMCC2 ADAMTS18 CDH2	3.05e-03	130	135	4	EFO_0004641
Disease	electrocardiography	CACNB2 CEP85L SPEG NUP42 MAST4 SIPA1L1 ADAMTS18 CDH2	3.12e-03	530	135	8	EFO_0004327
Disease	neuroticism measurement	DOCK3 SETD1A ARPP21 AFF2 TRO ETFA GLIS3 MAGED2 SIPA1L1 RP1L1 KMT2A	3.13e-03	909	135	11	EFO_0007660
Disease	Neoplasm Metastasis	SREBF2 CIC NDRG1 MTHFR CDH2	3.29e-03	217	135	5	C0027627
Disease	ankylosing spondylitis (is_implicated_in)	MTHFR TNFRSF1B	3.38e-03	19	135	2	DOID:7147 (is_implicated_in)
Disease	Breast Carcinoma	APC2 GATA3 SREBF2 ARID1B NDRG1 PER3 MTHFR CDH2	3.41e-03	538	135	8	C0678222
Disease	cortical surface area measurement	ADAMTSL1 ETFA RALGPS2 GLIS3 MARCHF7 ARID1B FBXL7 MAST4 FAM13A UBTF RP1L1 ADAMTS18 ROBO1 NOVA1	3.50e-03	1345	135	14	EFO_0010736
Disease	attention deficit hyperactivity disorder (is_implicated_in)	DOCK3 MTHFR	3.74e-03	20	135	2	DOID:1094 (is_implicated_in)
Disease	diastolic blood pressure, systolic blood pressure	CACNB2 CLIP2 SPEG DOK7 RALGPS2 JPH2 ARID1B ACAN CDH2	3.78e-03	670	135	9	EFO_0006335, EFO_0006336
Disease	systemic lupus erythematosus	TMC2 TENT4A CLIP2 RALGPS2 CHD9 STIM1 IQCJ-SCHIP1 DOT1L MUC22 CDH2	3.79e-03	799	135	10	MONDO_0007915
Disease	brain measurement, neuroimaging measurement	CACNB2 RALGPS2 GLIS3 FBXL7 MAST4 ADAMTS18 ROBO1 IQCJ-SCHIP1	3.90e-03	550	135	8	EFO_0004346, EFO_0004464
Disease	congenital heart disease (implicated_via_orthology)	CHD9 KMT2A PLCB2	3.94e-03	69	135	3	DOID:1682 (implicated_via_orthology)
Disease	HbA1c measurement	DOK7 ZNF185 ETFA GLIS3 SMG5 TNRC6C SENP1 IQCJ-SCHIP1 CDH3	3.96e-03	675	135	9	EFO_0004541
Disease	pulse pressure measurement, alcohol drinking	CACNB2 MTHFR KCNK3	4.10e-03	70	135	3	EFO_0004329, EFO_0005763
Disease	Precursor B-cell lymphoblastic leukemia	GATA3 KMT2A	4.12e-03	21	135	2	C1292769

Protein segments in the cluster

Peptide	Gene	Start	Entry
SASSDSGEGTSLDAG	CBARP	246	Q8N350
GTKSSSSASDGESEG	CTDP1	466	Q9Y5B0
VFTGSSSSSDLISGT	ERBIN	926	Q96RT1
SAESLVGSSGGSSSD	AEBP2	121	Q6ZN18
VGSSGGSSSDETRSL	AEBP2	126	Q6ZN18
EGTGSTATSSSSTAG	EIF3H	6	O15372
TATSSSSTAGAAGKG	EIF3H	11	O15372
SIAGSEGSISASAAS	ARHGEF25	36	Q86VW2
SLSSSSSGSGTDCLD	CFAP97	176	Q9P2B7
GGKSSSSSSASAAAA	CKAP4	76	Q07065
SGGSGSSSESESSSE	AFF2	481	P51816
TSESSIGDSSSSLSG	ARHGEF38	681	Q9NXL2
ESGSAAGTTTSASGS	EVX2	146	Q03828
ASSSSSSSSAVAGGA	AJAP1	131	Q9UKB5
SSAGTGASVSAAATA	AGAP2	226	Q99490
GRTSTGSASSSAAVA	CLIP2	21	Q9UDT6
GSASSSAAVAASSKE	CLIP2	26	Q9UDT6
GGSAAALSSSSSSSA	ARID1B	111	Q8NFD5
GTEATLSSAVSASGS	ARID1B	761	Q8NFD5
AESSRGLSAGSLSES	CCM2	171	Q9BSQ5
DESSSSGSLFATVGS	DOT1L	966	Q8TEK3
SGSSSSDSESSSGSD	EAF1	191	Q96JC9
SKAGSESSSSAGSSG	ARPP21	406	Q9UBL0
ESSSSAGSSGSLSRT	ARPP21	411	Q9UBL0
SVAAALASDSSSGAS	ADAMTS18	41	Q8TE60
DDSSSHSGSESSSGS	AFF4	426	Q9UHB7
RFKGSDGSTSSDTTS	CACNB2	51	Q08289
SDSKSSSESGSGESS	AP3B2	701	Q13367
SSSASSSFSEEGAVG	NFE2L1	511	Q14494
SLGSDSTLSSASGSL	RAB11FIP5	251	Q9BXF6
ALSGFGSSVGSSASS	PUM2	566	Q8TB72
GTSRVEAGSSTSGSD	CAPN15	306	O75808
LSGSQGASALSTSGS	DSG3	901	P32926
TGSLKSTSSSTGAAD	MSH3	31	P20585
EGSASSGSESSKDSS	MTHFR	16	P42898
SDLSSGASDAASTAS	JPH2	251	Q9BR39
SDSGRASSKSGSSSS	LZTS3	276	O60299
ASASTSGGFSAGASL	MAGED2	561	Q9UNF1
FTTGSDTTTGSTAGS	MUC22	111	E2RYF6
EGSGTTAASTAGSET	MUC22	831	E2RYF6
SGSGTTTASTAGSET	MUC22	1341	E2RYF6
IGSEATTSSAAGSEA	MUC22	1411	E2RYF6
VTAADSSGSAATSTF	HIPK1	86	Q86Z02
GGSAHTTDTASSTAA	KCNK3	276	O14649
ASGGSGSQARTSFSS	KRT79	21	Q5XKE5
SSSGSLGSESTNLAA	APPL1	426	Q9UKG1
GGAALSSSTAGSSAA	EZHIP	56	Q86X51
LELSSDGGSSSSGRS	MAPK8IP2	276	Q13387
FSSSLRTSSTGDAGG	ADAMTSL1	1141	Q8N6G6
SESPSRTGSAASGSS	PER3	1051	P56645
GGKTGATSSEATSSE	MUC19	1816	Q7Z5P9
TLSGGSSTTRSSDGT	MUC19	2551	Q7Z5P9
ATTLTGDRSSTGSES	MUC19	6751	Q7Z5P9
FSTATTSSGASGITR	MUC19	7251	Q7Z5P9
AKEGGASIDSSASSS	MYF6	201	P23409
SRTASGSSVTSLDGT	NDRG1	326	Q92597
SLSNSSGASADAGST	HOXA5	121	P20719
SLGSGSSRDSISSDS	KDM4A	511	O75164
SSARVSAGGSSFSSG	KRT24	16	Q2M2I5
GTSAATTTAATSGFS	NUP214	1821	P35658
SDTLDGNSSSAGSSC	PABIR1	241	Q96E09
DSESGTLSASSATSA	FAM13A	391	O94988
ADGASTETSASGTSQ	HUWE1	2016	Q7Z6Z7
GSSASSVSSLSGSDV	TENT4A	586	Q5XG87
SGDLDSSGLTSTVGS	ACAN	896	P16112
FGAAASTSSGISTSA	NUP42	271	O15504
SDILDGSSSSSGLSS	PABIR2	201	Q7Z309
SSSSSSESSAAGLGA	ARHGAP33	691	O14559
SESTGGSSESRSLDS	ARHGAP29	541	Q52LW3
SRGSMTALGGASSST	GATA3	201	P23771
SGSLLSSGSQESDSS	FRMD4A	366	Q9P2Q2
ASALSSGSESSDRSG	APC2	1976	O95996
GSEKADASSGSDSTS	CHD9	2871	Q3L8U1
SGLDGSNSTLSGSAS	DOCK3	1876	Q8IZD9
ASSLSGASEEGSASE	CCDC106	136	Q9BWC9
SHSASEEASGSDSGS	CHD2	21	O14647
SEGKGSSSISSDVSS	FBXL7	11	Q9UJT9
SDSGSTSGGSKSQSR	CCNL2	406	Q96S94
SSSSSLFGESLRSGA	GLIS3	736	Q8NEA6
EGSGSTAGSVSSLNS	CDH4	871	P55283
SKSSGGSSSGTITDE	ANKS6	761	Q68DC2
SDSGDTGIGTSCSDS	CEP85L	61	Q5SZL2
KTSSAESSSAESGSG	CDK11A	276	Q9UQ88
DVGDGSSTSSTGSTD	CCDC85A	206	Q96PX6
SAASSSATTGGSTSD	MARCHF7	451	Q9H992
ASSPGASSAESSSGS	MAST4	31	O15021
SAASSDTSSAKAAGG	MAST4	2476	O15021
TTAKSSSSEGGVSAS	KANSL3	696	Q9P2N6
GGAAAASAASSSSAS	KMT2A	76	Q03164
ESASASSSGSERDAG	DGKZ	16	Q13574
SGGDDRSLSSSSSEA	DOK7	256	Q18PE1
LATSSSSLGFESESG	C4orf54	296	D6RIA3
GSDAASLSSLTSSAS	CDH3	786	P22223
EGSGSTAGSLSSLNS	CDH2	861	P19022
AESSTLSSGISIGSS	RALGPS2	386	Q86X27
ASEASASGSTAGGTA	NOVA1	366	P51513
ESGSLGNSSGSDVTS	ISL2	326	Q96A47
SEGSSNTTEATSGSG	RTL1	26	A6NKG5
ARGTGSGEDSSTSSS	RTN2	151	O75298
SAEGGSTSSTLRAAA	GTF2F1	391	P35269
AKAASSGTTASEGSS	TNRC6C	386	Q9HCJ0
SSGAVATTTSSAGDH	SRRM2	2476	Q9UQ35
DSTSSGSSALSRNGS	TNFRSF21	561	O75509
SASASSAGAGSNSGA	TMCC2	481	O75069
SARASEGSDSGSDKS	SMG5	486	Q9UPR3
RGSGDSSTSTSTSRG	TMEM121B	41	Q9BXQ6
STATAGSGSSANLDA	NHSL2	1156	Q5HYW2
SSSASLASAGESTGK	NKTR	1196	P30414
GSDAGSSSSSSRASS	SCHIP1	31	P0DPB3
SGGSAEDSVGSSSVT	PTPRCAP	21	Q14761
TSFDAAATSGGSASS	ETFA	171	P13804
AATSGGSASSEKASS	ETFA	176	P13804
RETTGSESDGGDSSS	SH3KBP1	176	Q96B97
IGSDTSSSGSASILT	SENP1	246	Q9P0U3
SNLSSSSDTGSVGGT	SIPA1L1	1151	O43166
EGTASTALGNSSSLS	SIGLEC7	251	Q9Y286
FTDSGKGSASSGSTT	SAMD14	241	Q8IZD0
TSGAAGDRSSSSSSL	MSH4	56	O15457
DGLSVSSSSTGSLGS	WHRN	6	Q9P202
SVASSSAEEESSGGG	SOWAHC	246	Q53LP3
DSGGMSAVSDGSSSS	TSC22D1	931	Q15714
SAVSDGSSSSLAASA	TSC22D1	936	Q15714
LGSDAGSSSSSSRAS	IQCJ-SCHIP1	106	B3KU38
ATGTSSGANSEESTA	STIM1	31	Q13586
SSDSSSSSDGEGALR	SETD1A	1376	O15047
AFSSTGLGSSAAAAS	SP9	231	P0CG40
SGQASGADSTDNSSS	STON2	181	Q8WXE9
ISSASTLSSLSAEGG	SHANK1	1691	Q9Y566
SSSASAATSFSLGSG	CIC	541	Q96RK0
LASSSTDSSGTSSEG	INPP5J	846	Q15735
LVAGSSDSSSSGSAS	ZNF653	191	Q96CK0
TGRAFVGSDSGSSST	TIAM1	361	Q13009
VGSDSGSSSTGDAAR	TIAM1	366	Q13009
SAESLGSEASATSGS	SPEG	2521	Q15772
RSEEGASSDSSASTG	RP1L1	526	Q8IWN7
ASSDSSASTGSHEGS	RP1L1	531	Q8IWN7
TSTSFSSEASISFGG	TRO	801	Q12816
SSGSAVGTSSKAEAS	PTGIR	366	P43119
SSSSNGRGSSSGAVD	SREBF2	71	Q12772
QASSSGSSDSLGSGE	REM2	91	Q8IYK8
GRSSVSSSDGSFFTD	ROBO1	1386	Q9Y6N7
TSSSKDTGGEAEGSS	PLCB2	471	Q00722
SSSVASSLASSAGSG	UNKL	376	Q9H9P5
GSSSSSGSRRASASG	ZSWIM8	1191	A7E2V4
SSLKEGTSSSGSVDS	ZBED6	831	P86452
GTSSSGSVDSSAVDN	ZBED6	836	P86452
SVSTSESSAGAGTGT	ZNF362	126	Q5T0B9
SGGSSSSSSSSSEED	SNAPC4	531	Q5SXM2
SGAGEARASTGSSDS	TNFRSF1B	356	P20333
SSLASSASGGESLSE	TMC2	136	Q8TDI7
EGSSSSSSSSGDSSD	UBTF	746	P17480
SGESSFESTGTGLSR	HIVEP2	951	P31629
SSLDAGTLSDTTASA	UBR4	2851	Q5T4S7
EGSTAATDGSTLRTS	UBR4	2871	Q5T4S7
SASSDAGSGSRRSSG	UBQLN4	126	Q9NRR5
DIGSERGSSSATSVS	ZNF185	366	O15231
LTVSSGSSRGSLASS	WWC3	361	Q9ULE0
SSAHSTTSGRGESTT	MUC12	2761	Q9UKN1
ARASDSSSSSSLGSG	LRFN2	616	Q9ULH4
SSSSSSLGSGEAAGL	LRFN2	621	Q9ULH4