Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	lysine-acetylated histone binding	BRD3 BRD2 BRD4 ZMYND8	4.90e-07	30	43	4	GO:0070577
GeneOntologyMolecularFunction	acetylation-dependent protein binding	BRD3 BRD2 BRD4 ZMYND8	5.62e-07	31	43	4	GO:0140033
GeneOntologyMolecularFunction	histone binding	MBTD1 BRD3 BRD2 BRD4 HIRA ZMYND8	2.08e-05	265	43	6	GO:0042393
GeneOntologyMolecularFunction	modification-dependent protein binding	MBTD1 BRD3 BRD2 BRD4 ZMYND8	7.79e-05	206	43	5	GO:0140030
GeneOntologyMolecularFunction	actin filament binding	MYH11 MYH13 XIRP2 CD2AP MPRIP	1.23e-04	227	43	5	GO:0051015
GeneOntologyMolecularFunction	chromatin binding	H1-10 NCOA6 MBTD1 BRD3 BRD2 EP400 BRD4 HIRA	1.56e-04	739	43	8	GO:0003682
GeneOntologyMolecularFunction	cadherin binding	APC H1-10 TBC1D10A CD2AP MPRIP	7.76e-04	339	43	5	GO:0045296
GeneOntologyMolecularFunction	transcription coregulator activity	NRG1 NCOA6 MYBBP1A BRD4 HIRA ZMYND8	1.22e-03	562	43	6	GO:0003712
GeneOntologyMolecularFunction	cell adhesion molecule binding	APC H1-10 NRG1 TBC1D10A CD2AP MPRIP	1.69e-03	599	43	6	GO:0050839
GeneOntologyMolecularFunction	cytoskeletal protein binding	APC MYH11 PDE6G PTPRC MYH13 XIRP2 CD2AP MPRIP	2.13e-03	1099	43	8	GO:0008092
GeneOntologyMolecularFunction	protein kinase regulator activity	APC NOLC1 NRG1 ALK	2.29e-03	259	43	4	GO:0019887
GeneOntologyMolecularFunction	spectrin binding	PDE6G PTPRC	2.43e-03	34	43	2	GO:0030507
GeneOntologyMolecularFunction	snoRNA binding	NOLC1 BMS1	2.43e-03	34	43	2	GO:0030515
GeneOntologyMolecularFunction	protein domain specific binding	NOLC1 NCOA6 TBC1D10A UBR5 CD2AP EXOC4 ZMYND8	2.46e-03	875	43	7	GO:0019904
GeneOntologyMolecularFunction	protein tyrosine kinase activator activity	NRG1 ALK	2.72e-03	36	43	2	GO:0030296
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	NOLC1 NRG1 NCOA6 MYBBP1A BRD3 BRD4 HIRA ZMYND8	2.98e-03	1160	43	8	GO:0030674
GeneOntologyMolecularFunction	microfilament motor activity	MYH11 MYH13	3.03e-03	38	43	2	GO:0000146
GeneOntologyMolecularFunction	chromatin-protein adaptor activity	NCOA6 BRD4	3.52e-03	41	43	2	GO:0140463
GeneOntologyMolecularFunction	actin binding	MYH11 MYH13 XIRP2 CD2AP MPRIP	3.53e-03	479	43	5	GO:0003779
GeneOntologyMolecularFunction	kinase regulator activity	APC NOLC1 NRG1 ALK	4.12e-03	305	43	4	GO:0019207
GeneOntologyBiologicalProcess	chromatin organization	H1-10 MBTD1 MYBBP1A BRD3 BRD2 EP400 UBR5 BRD4 HIRA ZMYND8	7.48e-06	896	41	10	GO:0006325
GeneOntologyBiologicalProcess	protein-DNA complex organization	H1-10 MBTD1 MYBBP1A BRD3 BRD2 EP400 UBR5 BRD4 HIRA ZMYND8	1.93e-05	999	41	10	GO:0071824
GeneOntologyBiologicalProcess	DNA recombination	H1-10 MBTD1 PTPRC EP400 ZMYND8 SANBR	8.22e-05	368	41	6	GO:0006310
GeneOntologyBiologicalProcess	chromatin remodeling	H1-10 MYBBP1A BRD3 BRD2 EP400 UBR5 BRD4 HIRA	8.92e-05	741	41	8	GO:0006338
GeneOntologyBiologicalProcess	positive regulation of T-helper 17 cell lineage commitment	BRD2 BRD4	1.07e-04	8	41	2	GO:2000330
GeneOntologyBiologicalProcess	positive T cell selection	PTPRC BRD2 BRD4	1.59e-04	53	41	3	GO:0043368
GeneOntologyBiologicalProcess	regulation of T-helper 17 cell lineage commitment	BRD2 BRD4	2.10e-04	11	41	2	GO:2000328
GeneOntologyBiologicalProcess	regulation of DNA recombination	H1-10 MBTD1 PTPRC EP400	2.21e-04	150	41	4	GO:0000018
GeneOntologyBiologicalProcess	protein localization to organelle	APC NOLC1 BRD3 BRD2 UBR5 VPS13C CD2AP NOL8 ZMYND8	2.37e-04	1091	41	9	GO:0033365
GeneOntologyBiologicalProcess	protein localization to chromatin	BRD3 BRD2 ZMYND8	2.92e-04	65	41	3	GO:0071168
GeneOntologyBiologicalProcess	positive regulation of T-helper 17 cell differentiation	BRD2 BRD4	3.46e-04	14	41	2	GO:2000321
GeneOntologyBiologicalProcess	T cell selection	PTPRC BRD2 BRD4	3.49e-04	69	41	3	GO:0045058
GeneOntologyBiologicalProcess	positive regulation of calcium-mediated signaling	NRG1 PTPRC EXOC4	3.64e-04	70	41	3	GO:0050850
GeneOntologyCellularComponent	muscle myosin complex	MYH11 MYH13	4.43e-04	16	41	2	GO:0005859
GeneOntologyCellularComponent	chromatin	H1-10 MBTD1 MYBBP1A BRD3 BRD2 EP400 UBR5 BRD4 HIRA ZMYND8	4.53e-04	1480	41	10	GO:0000785
GeneOntologyCellularComponent	myosin filament	MYH11 MYH13	1.09e-03	25	41	2	GO:0032982
GeneOntologyCellularComponent	contractile actin filament bundle	MYH11 XIRP2 MPRIP	1.21e-03	107	41	3	GO:0097517
GeneOntologyCellularComponent	stress fiber	MYH11 XIRP2 MPRIP	1.21e-03	107	41	3	GO:0001725
GeneOntologyCellularComponent	myosin II complex	MYH11 MYH13	1.37e-03	28	41	2	GO:0016460
GeneOntologyCellularComponent	actomyosin	MYH11 XIRP2 MPRIP	1.56e-03	117	41	3	GO:0042641
GeneOntologyCellularComponent	actin filament bundle	MYH11 XIRP2 MPRIP	1.60e-03	118	41	3	GO:0032432
GeneOntologyCellularComponent	NuA4 histone acetyltransferase complex	MBTD1 EP400	1.79e-03	32	41	2	GO:0035267
GeneOntologyCellularComponent	H4/H2A histone acetyltransferase complex	MBTD1 EP400	1.79e-03	32	41	2	GO:0043189
GeneOntologyCellularComponent	contractile muscle fiber	DNAJB4 MYH11 MYH13 XIRP2	2.45e-03	290	41	4	GO:0043292
GeneOntologyCellularComponent	nucleosome	H1-10 MBTD1 EP400	2.50e-03	138	41	3	GO:0000786
Domain	BET	BRD3 BRD2 BRD4	4.54e-08	4	43	3	PF17035
Domain	NET_dom	BRD3 BRD2 BRD4	4.54e-08	4	43	3	IPR027353
Domain	NET	BRD3 BRD2 BRD4	4.54e-08	4	43	3	PS51525
Domain	Bromodomain	BRD3 BRD2 BRD4 ZMYND8	1.70e-06	38	43	4	PF00439
Domain	BROMODOMAIN_2	BRD3 BRD2 BRD4 ZMYND8	2.32e-06	41	43	4	PS50014
Domain	BROMO	BRD3 BRD2 BRD4 ZMYND8	2.56e-06	42	43	4	SM00297
Domain	Bromodomain	BRD3 BRD2 BRD4 ZMYND8	2.56e-06	42	43	4	IPR001487
Domain	-	BRD3 BRD2 BRD4 ZMYND8	2.56e-06	42	43	4	1.20.920.10
Domain	Bromodomain_CS	BRD3 BRD2 BRD4	2.85e-05	26	43	3	IPR018359
Domain	BROMODOMAIN_1	BRD3 BRD2 BRD4	8.36e-05	37	43	3	PS00633
Domain	Myosin_N	MYH11 MYH13	5.33e-04	15	43	2	IPR004009
Domain	Myosin_N	MYH11 MYH13	5.33e-04	15	43	2	PF02736
Domain	Myosin_tail_1	MYH11 MYH13	7.74e-04	18	43	2	PF01576
Domain	Myosin_tail	MYH11 MYH13	7.74e-04	18	43	2	IPR002928
Domain	Myosin-like_IQ_dom	MYH11 MYH13	8.64e-04	19	43	2	IPR027401
Domain	-	MYH11 MYH13	8.64e-04	19	43	2	4.10.270.10
Domain	MYOSIN_MOTOR	MYH11 MYH13	3.45e-03	38	43	2	PS51456
Domain	Myosin_head	MYH11 MYH13	3.45e-03	38	43	2	PF00063
Domain	Myosin_head_motor_dom	MYH11 MYH13	3.45e-03	38	43	2	IPR001609
Domain	MYSc	MYH11 MYH13	3.45e-03	38	43	2	SM00242
Pubmed	Human transcription factor protein interaction networks.	NOLC1 H1-10 PUM3 NCOA6 MBTD1 MYBBP1A CCDC59 BRD2 TEX10 ANKHD1 EP400 HIRA EXOC4 MPRIP ZMYND8 BMS1	5.64e-12	1429	43	16	35140242
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	APC PUM3 FAM184A BRD3 CCDC59 BRD2 TEX10 ANKHD1 EP400 TBC1D10A CD2AP HIRA NOL8 MPRIP ZMYND8 BMS1	1.13e-11	1497	43	16	31527615
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	H1-10 MYBBP1A BRD3 BRD2 EP400 BRD4 CD2AP EXOC4 ZMYND8	1.13e-09	394	43	9	27248496
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	NOLC1 H1-10 PUM3 NCOA6 MYBBP1A BRD2 EP400 ALK BRD4 CD2AP NOL8 ZMYND8	1.19e-09	954	43	12	36373674
Pubmed	Comparative structure-function analysis of bromodomain and extraterminal motif (BET) proteins in a gene-complementation system.	BRD3 BRD2 BRD4	1.76e-09	3	43	3	31792058
Pubmed	Bromo- and extraterminal domain chromatin regulators serve as cofactors for murine leukemia virus integration.	BRD3 BRD2 BRD4	1.76e-09	3	43	3	24049186
Pubmed	BET Proteins Exhibit Transcriptional and Functional Opposition in the Epithelial-to-Mesenchymal Transition.	BRD3 BRD2 BRD4	1.76e-09	3	43	3	29437854
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	NCOA6 MYBBP1A TEX10 EP400 BRD4 NOL8 ZMYND8 BMS1	1.97e-09	283	43	8	30585729
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	NOLC1 H1-10 NCOA6 MBTD1 MYBBP1A BRD3 BRD2 EP400 CDCA7L BRD4 HIRA NOL8 ZMYND8	3.19e-09	1294	43	13	30804502
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	NOLC1 H1-10 PUM3 MYBBP1A TEX10 ANKHD1 EP400 UBR5 MAP4K5 HIRA EXOC4 MPRIP BMS1	5.43e-09	1353	43	13	29467282
Pubmed	Expression of BET genes in testis of men with different spermatogenic impairments.	BRD3 BRD2 BRD4	7.04e-09	4	43	3	22035730
Pubmed	Regulation of NO synthesis, local inflammation, and innate immunity to pathogens by BET family proteins.	BRD3 BRD2 BRD4	7.04e-09	4	43	3	24248598
Pubmed	Selective inhibition of CD4+ T-cell cytokine production and autoimmunity by BET protein and c-Myc inhibitors.	BRD3 BRD2 BRD4	7.04e-09	4	43	3	22912406
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	NOLC1 DNAJB4 H1-10 FAM184A MYBBP1A FAM193A BRD2 UBR5 MAP4K5 NOL8 EXOC4 MPRIP BMS1	1.67e-08	1487	43	13	33957083
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	NOLC1 H1-10 NCOA6 MYBBP1A BRD3 PTPRC BRD2 EP400 BRD4 ZMYND8	2.78e-08	774	43	10	15302935
Pubmed	HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.	NOLC1 MYBBP1A TEX10 BRD4 NOL8 ZMYND8	2.87e-08	148	43	6	32538781
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	NOLC1 DNAJB4 MYBBP1A BRD3 BRD2 TEX10 EP400 UBR5 CDCA7L BRD4 ZMYND8	3.00e-08	1014	43	11	32416067
Pubmed	Intron 1-Mediated Regulation of EGFR Expression in EGFR-Dependent Malignancies Is Mediated by AP-1 and BET Proteins.	BRD3 BRD2 BRD4	3.51e-08	6	43	3	31444232
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	APC FAM193A ANKHD1 UBR5 BRD4 CD2AP EXOC4 ZMYND8	4.09e-08	418	43	8	34709266
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	APC NOLC1 MYBBP1A BRD3 BRD2 TEX10 EP400 BRD4 HIRA ZMYND8 BMS1	5.80e-08	1082	43	11	38697112
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	H1-10 PUM3 MYBBP1A BRD3 TEX10 CDCA7L NOL8 MPRIP ZMYND8 BMS1	6.45e-08	847	43	10	35850772
Pubmed	BRD4 Promotes Gastric Cancer Progression and Metastasis through Acetylation-Dependent Stabilization of Snail.	BRD3 BRD2 BRD4	9.82e-08	8	43	3	31311807
Pubmed	The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.	NOLC1 H1-10 PUM3 MYBBP1A CCDC59 TEX10 NOL8 BMS1	1.24e-07	483	43	8	36912080
Pubmed	Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT-mTORC1 activation.	BRD3 BRD2 BRD4 ZMYND8	1.79e-07	40	43	4	28805822
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	NOLC1 BRD3 BRD2 BRD4 ZMYND8	1.82e-07	103	43	5	32744500
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	MBTD1 MYBBP1A BRD2 TEX10 EP400 BRD4 BMS1	1.87e-07	339	43	7	30415952
Pubmed	The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.	H1-10 PUM3 MYBBP1A TEX10 HIRA NOL8 BMS1	2.28e-07	349	43	7	25665578
Pubmed	Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4.	BRD3 BRD2 BRD4	2.88e-07	11	43	3	28805820
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	NOLC1 H1-10 PUM3 MYBBP1A CCDC59 TEX10 NOL8 EXOC4 BMS1	3.11e-07	759	43	9	35915203
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	NCOA6 MYBBP1A ANKHD1 EP400 BRD4 CD2AP EXOC4 MPRIP	3.27e-07	549	43	8	38280479
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	APC NOLC1 MYBBP1A MYH13 EP400 UBR5 VPS13C NOL8 BMS1	3.78e-07	777	43	9	35844135
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	APC H1-10 MBTD1 BRD3 BRD2 EP400 BRD4	5.51e-07	398	43	7	35016035
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	PUM3 MYBBP1A MYH11 CCDC59 MYH13 TEX10 ANKHD1 EP400 ALK MPRIP BMS1	6.17e-07	1371	43	11	36244648
Pubmed	The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.	NOLC1 BRD3 BRD2 BRD4	7.63e-07	57	43	4	21555454
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	NOLC1 H1-10 MBTD1 BRD3 BRD2 ANKHD1 EP400 UBR5 BRD4 ZMYND8	8.13e-07	1116	43	10	31753913
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	MBTD1 CCDC59 TEX10 ANKHD1 EP400 UBR5 HIRA ZMYND8 BMS1	8.55e-07	857	43	9	25609649
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	APC PUM3 MYBBP1A TEX10 EP400 UBR5 MPRIP	1.08e-06	440	43	7	34244565
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	PUM3 BRD3 CCDC59 BRD2 EP400 CD2AP HIRA EXOC4	1.10e-06	645	43	8	25281560
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	NOLC1 H1-10 PUM3 MYBBP1A TEX10 ANKHD1 UBR5 BMS1	1.20e-06	653	43	8	22586326
Pubmed	PRC1 and PRC2 are not required for targeting of H2A.Z to developmental genes in embryonic stem cells.	NCOA6 MBTD1 MYBBP1A EP400	1.30e-06	65	43	4	22496869
Pubmed	Bromodomain and extra-terminal domain (BET) proteins regulate melanocyte differentiation.	BRD2 BRD4	1.49e-06	2	43	2	32151278
Pubmed	BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism.	BRD2 BRD4	1.49e-06	2	43	2	23255218
Pubmed	A structural basis for BRD2/4-mediated host chromatin interaction and oligomer assembly of Kaposi sarcoma-associated herpesvirus and murine gammaherpesvirus LANA proteins.	BRD2 BRD4	1.49e-06	2	43	2	24146614
Pubmed	Chromosomal localization, gene structure and transcription pattern of the ORFX gene, a homologue of the MHC-linked RING3 gene.	BRD3 BRD2	1.49e-06	2	43	2	9373153
Pubmed	BRD3 and BRD4 BET Bromodomain Proteins Differentially Regulate Skeletal Myogenesis.	BRD3 BRD4	1.49e-06	2	43	2	28733670
Pubmed	BET bromodomain proteins mediate downstream signaling events following growth factor stimulation in human lung fibroblasts and are involved in bleomycin-induced pulmonary fibrosis.	BRD2 BRD4	1.49e-06	2	43	2	23115324
Pubmed	Bromodomain and extra-terminal domain bromodomain inhibition prevents synovial inflammation via blocking IκB kinase-dependent NF-κB activation in rheumatoid fibroblast-like synoviocytes.	BRD2 BRD4	1.49e-06	2	43	2	26324948
Pubmed	The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription.	BRD3 BRD2	1.49e-06	2	43	2	18406326
Pubmed	Viral E protein neutralizes BET protein-mediated post-entry antagonism of SARS-CoV-2.	BRD2 BRD4	1.49e-06	2	43	2	35839775
Pubmed	Brd4-Brd2 isoform switching coordinates pluripotent exit and Smad2-dependent lineage specification.	BRD2 BRD4	1.49e-06	2	43	2	28588073
Pubmed	Recruitment of Brd3 and Brd4 to acetylated chromatin is essential for proinflammatory cytokine-induced matrix-degrading enzyme expression.	BRD3 BRD4	1.49e-06	2	43	2	30786900
Pubmed	Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen interacts with bromodomain protein Brd4 on host mitotic chromosomes.	BRD2 BRD4	1.49e-06	2	43	2	16940503
Pubmed	BRD3/4 inhibition and FLT3-ligand deprivation target pathways that are essential for the survival of human MLL-AF9+ leukemic cells.	BRD3 BRD4	1.49e-06	2	43	2	29240787
Pubmed	WHAT do viruses BET on?	BRD2 BRD4	1.49e-06	2	43	2	20036832
Pubmed	SARS-CoV-2 E protein interacts with BRD2 and BRD4 SEED domains and alters transcription in a different way than BET inhibition.	BRD2 BRD4	1.49e-06	2	43	2	39066826
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	NOLC1 MYBBP1A BRD3 BRD2 EP400 CDCA7L BRD4	1.64e-06	469	43	7	27634302
Pubmed	Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.	BRD3 BRD2 BRD4 ZMYND8	2.31e-06	75	43	4	25593309
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	APC FAM193A ANKHD1 CD2AP HIRA NOL8 EXOC4 MPRIP	2.59e-06	724	43	8	36232890
Pubmed	ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.	NOLC1 H1-10 MYBBP1A TEX10 ZMYND8 BMS1	3.16e-06	330	43	6	33301849
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	NOLC1 NCOA6 ANKHD1 EP400 VPS13C BMS1 SANBR	3.63e-06	529	43	7	14621295
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	NOLC1 MYBBP1A BRD3 BRD2 TEX10 BRD4 ZMYND8	3.82e-06	533	43	7	30554943
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	NOLC1 NCOA6 MYBBP1A EP400 HIRA ZMYND8	3.82e-06	341	43	6	32971831
Pubmed	In vitro nuclear interactome of the HIV-1 Tat protein.	PUM3 BRD3 BRD2 EP400 CDCA7L	4.26e-06	195	43	5	19454010
Pubmed	Targeting BRD3 eradicates nuclear TYRO3-induced colorectal cancer metastasis.	APC BRD3	4.48e-06	3	43	2	37043564
Pubmed	HIRA-mediated loading of histone variant H3.3 controls androgen-induced transcription by regulation of AR/BRD4 complex assembly at enhancers.	BRD4 HIRA	4.48e-06	3	43	2	37638746
Pubmed	NF-κB signaling activation via increases in BRD2 and BRD4 confers resistance to the bromodomain inhibitor I-BET151 in U937 cells.	BRD2 BRD4	4.48e-06	3	43	2	30300821
Pubmed	Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation.	BRD2 BRD4	4.48e-06	3	43	2	28262505
Pubmed	BRD-NUT oncoproteins: a family of closely related nuclear proteins that block epithelial differentiation and maintain the growth of carcinoma cells.	BRD3 BRD4	4.48e-06	3	43	2	17934517
Pubmed	Bromodomain and Extraterminal (BET) Protein Inhibition Restores Redox Balance and Inhibits Myofibroblast Activation.	BRD3 BRD4	4.48e-06	3	43	2	31119153
Pubmed	Blockade of oncogenic IκB kinase activity in diffuse large B-cell lymphoma by bromodomain and extraterminal domain protein inhibitors.	BRD2 BRD4	4.48e-06	3	43	2	25049379
Pubmed	Elucidation of Resistance Mechanisms to Second-Generation ALK Inhibitors Alectinib and Ceritinib in Non-Small Cell Lung Cancer Cells.	NRG1 ALK	4.48e-06	3	43	2	26992917
Pubmed	[Expression of BRD7-interacting proteins,BRD2 and BRD3, in nasopharyngeal carcinoma tissues].	BRD3 BRD2	4.48e-06	3	43	2	12600283
Pubmed	Phylogeny and structure of the RING3 gene.	BRD3 BRD2	4.48e-06	3	43	2	8781126
Pubmed	Putative tumor suppressor EDD interacts with and up-regulates APC.	APC UBR5	4.48e-06	3	43	2	18076571
Pubmed	Metabolically Derived Lysine Acylations and Neighboring Modifications Tune the Binding of the BET Bromodomains to Histone H4.	BRD3 BRD2	4.48e-06	3	43	2	28945351
Pubmed	Functional proteomics mapping of a human signaling pathway.	NCOA6 EVC2 PTPRC TEX10 UBR5 BRD4 ZMYND8	7.49e-06	591	43	7	15231748
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	NOLC1 MYBBP1A BRD3 MYNN MYH11 BRD2 MYH13 TEX10 SNX25 SANBR	7.98e-06	1442	43	10	35575683
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	BRD2 TEX10 EP400 BRD4 NOL8	8.00e-06	222	43	5	37071664
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	H1-10 MYBBP1A BRD2 TEX10 ANKHD1 EXOC4 MPRIP	8.35e-06	601	43	7	33658012
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	NOLC1 H1-10 PUM3 MYBBP1A BRD2 ZMYND8 BMS1	8.71e-06	605	43	7	28977666
Pubmed	LYAR potentiates rRNA synthesis by recruiting BRD2/4 and the MYST-type acetyltransferase KAT7 to rDNA.	BRD2 BRD4	8.94e-06	4	43	2	31504794
Pubmed	The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability.	APC ZMYND8	8.94e-06	4	43	2	33932349
Pubmed	Targeting the EWS-ETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma.	BRD3 BRD4	8.94e-06	4	43	2	26623725
Pubmed	Genomic analysis of Meckel-Gruber syndrome in Arabs reveals marked genetic heterogeneity and novel candidate genes.	EVC2 EXOC4	8.94e-06	4	43	2	23169490
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	NCOA6 MYBBP1A MYH13 SNX25 MPRIP	1.03e-05	234	43	5	36243803
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	NCOA6 FAM193A EP400 XIRP2 MAP4K5 ZMYND8	1.43e-05	430	43	6	35044719
Pubmed	Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes.	NCOA6 UBR5 CDCA7L CD2AP	1.45e-05	119	43	4	23508102
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	NOLC1 H1-10 PUM3 MYBBP1A FAM193A ANKHD1 UBR5	1.46e-05	655	43	7	35819319
Pubmed	Bromodomain and extraterminal proteins suppress NF-E2-related factor 2-mediated antioxidant gene expression.	BRD2 BRD4	1.49e-05	5	43	2	24733848
Pubmed	The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.	NOLC1 PUM3 MYBBP1A TEX10 UBR5	1.50e-05	253	43	5	29911972
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	NOLC1 MYBBP1A FAM193A ANKHD1 EP400 NOL8 MPRIP ZMYND8	1.65e-05	934	43	8	33916271
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	NCOA6 EP400 BRD4 HIRA ZMYND8	1.98e-05	268	43	5	33640491
Pubmed	Broader expression of the mouse platelet factor 4-cre transgene beyond the megakaryocyte lineage.	APC PTPRC	2.23e-05	6	43	2	25393502
Pubmed	BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.	MBTD1 EP400 BRD4 ZMYND8	2.31e-05	134	43	4	25452129
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	NOLC1 CCDC59 TEX10 ANKHD1 BRD4 NOL8 BMS1	2.74e-05	723	43	7	34133714
Pubmed	Localization and characterization of proenkephalin-A as a potential biomarker for kidney disease in murine and human kidneys.	MYH11 PTPRC	3.12e-05	7	43	2	36354355
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	NOLC1 H1-10 PUM3 MYBBP1A BRD2 TEX10 EP400 UBR5	3.19e-05	1024	43	8	24711643
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	NRG1 BRD3 MYH13 TEX10 XIRP2 ZMYND8	3.22e-05	497	43	6	36774506
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	DNAJB4 PUM3 BRD2 UBR5 BRD4 NOL8 BMS1	3.58e-05	754	43	7	33060197
Pubmed	CRL3-SPOP ubiquitin ligase complex suppresses the growth of diffuse large B-cell lymphoma by negatively regulating the MyD88/NF-κB signaling.	BRD2 ZMYND8	4.16e-05	8	43	2	31776466
Interaction	POLR1G interactions	NOLC1 PUM3 MYBBP1A BRD3 BRD2 TEX10 EP400 BRD4 NOL8 ZMYND8 BMS1	4.38e-09	489	43	11	int:POLR1G
Interaction	H2AC4 interactions	H1-10 MYBBP1A BRD2 TEX10 ANKHD1 EP400 UBR5 BRD4 CD2AP EXOC4 ZMYND8	6.24e-09	506	43	11	int:H2AC4
Interaction	RPS24 interactions	NOLC1 H1-10 PUM3 MYBBP1A CCDC59 TEX10 BRD4 NOL8 RBIS ZMYND8 BMS1	9.88e-09	529	43	11	int:RPS24
Interaction	MACROH2A2 interactions	PUM3 MYBBP1A BRD3 BRD2 TEX10 BRD4 ZMYND8 BMS1	1.34e-08	211	43	8	int:MACROH2A2
Interaction	NIFK interactions	NOLC1 PUM3 MYBBP1A BRD3 CCDC59 BRD2 TEX10 BRD4 NOL8 BMS1	1.84e-08	431	43	10	int:NIFK
Interaction	ZNF330 interactions	NOLC1 H1-10 PUM3 MYBBP1A BRD3 BRD2 TEX10 NOL8 ZMYND8 BMS1	2.54e-08	446	43	10	int:ZNF330
Interaction	H2BC26 interactions	MBTD1 BRD2 TEX10 EP400 BRD4 MPRIP BMS1	1.11e-07	183	43	7	int:H2BC26
Interaction	RPL31 interactions	NOLC1 H1-10 PUM3 MYBBP1A BRD3 CCDC59 BRD2 TEX10 BRD4 NOL8 BMS1	1.28e-07	680	43	11	int:RPL31
Interaction	MEN1 interactions	NOLC1 H1-10 PUM3 NCOA6 MYBBP1A TEX10 EP400 UBR5 CDCA7L HIRA NOL8 ZMYND8 BMS1	1.30e-07	1029	43	13	int:MEN1
Interaction	NOP56 interactions	NOLC1 H1-10 PUM3 MYBBP1A BRD3 BRD2 TEX10 BRD4 NOL8 BMS1	2.50e-07	570	43	10	int:NOP56
Interaction	NOLC1 interactions	APC NOLC1 BRD3 BRD2 MYH13 UBR5 BRD4 CD2AP	3.72e-07	325	43	8	int:NOLC1
Interaction	PHF21A interactions	APC FAM193A MYH13 ANKHD1 UBR5 BRD4 EXOC4 ZMYND8	5.60e-07	343	43	8	int:PHF21A
Interaction	DDX23 interactions	NOLC1 PUM3 MYBBP1A BRD2 TEX10 UBR5 BRD4 NOL8 BMS1	6.28e-07	480	43	9	int:DDX23
Interaction	POLR1E interactions	NOLC1 MYBBP1A BRD3 BRD2 TEX10 BRD4 NOL8 BMS1	6.52e-07	350	43	8	int:POLR1E
Interaction	SMC5 interactions	NOLC1 H1-10 PUM3 NCOA6 MYBBP1A BRD2 EP400 ALK BRD4 CD2AP NOL8 ZMYND8	7.67e-07	1000	43	12	int:SMC5
Interaction	H1-4 interactions	NOLC1 PUM3 MYBBP1A BRD2 TEX10 XIRP2 ALK BRD4 CD2AP BMS1	9.05e-07	656	43	10	int:H1-4
Interaction	RNF2 interactions	NOLC1 H1-10 PUM3 NCOA6 MBTD1 MYBBP1A TEX10 EP400 UBR5 BRD4 BMS1	1.41e-06	866	43	11	int:RNF2
Interaction	RPL15 interactions	NOLC1 PUM3 MYBBP1A CCDC59 TEX10 BRD4 NOL8 ZMYND8 BMS1	1.43e-06	530	43	9	int:RPL15
Interaction	APEX1 interactions	NOLC1 FAM184A BRD3 FAM193A BRD2 TEX10 ANKHD1 EP400 BRD4 NOL8 ZMYND8 BMS1 SANBR	1.45e-06	1271	43	13	int:APEX1
Interaction	SPDYE7P interactions	BRD3 BRD2 BRD4	1.96e-06	12	43	3	int:SPDYE7P
Interaction	HMGN4 interactions	PUM3 BRD3 BRD2 BRD4 BMS1	2.25e-06	100	43	5	int:HMGN4
Interaction	CAVIN1 interactions	NOLC1 MYBBP1A BRD3 BRD2 UBR5 CDCA7L BRD4	2.57e-06	292	43	7	int:CAVIN1
Interaction	WWTR1 interactions	NCOA6 MYBBP1A ANKHD1 EP400 BRD4 CD2AP EXOC4 MPRIP	2.64e-06	422	43	8	int:WWTR1
Interaction	MNDA interactions	H1-10 PUM3 MYBBP1A TEX10 NOL8 BMS1	2.78e-06	188	43	6	int:MNDA
Interaction	DNAJC9 interactions	NOLC1 DNAJB4 MYBBP1A BRD3 BRD2 BRD4 BMS1	2.81e-06	296	43	7	int:DNAJC9
Interaction	H2BC8 interactions	MBTD1 BRD3 CCDC59 BRD2 TEX10 EP400 BRD4 ZMYND8 BMS1	2.83e-06	576	43	9	int:H2BC8
Interaction	DMAP1 interactions	MBTD1 BRD3 BRD2 EP400 CDCA7L BRD4	3.05e-06	191	43	6	int:DMAP1
Interaction	CHD4 interactions	NOLC1 H1-10 PUM3 MYBBP1A BRD3 MYNN BRD2 ANKHD1 BRD4 ZMYND8 BMS1	3.06e-06	938	43	11	int:CHD4
Interaction	FGF8 interactions	PUM3 MYBBP1A ANKHD1 NOL8 BMS1	3.30e-06	108	43	5	int:FGF8
Interaction	MRGBP interactions	MBTD1 BRD3 BRD2 EP400 BRD4	3.45e-06	109	43	5	int:MRGBP
Interaction	C1orf226 interactions	BRD3 BRD2 MYH13 BRD4	4.88e-06	53	43	4	int:C1orf226
Interaction	H2BC12 interactions	NOLC1 H1-10 MYH11 BRD4 HIRA NOL8 RBIS	4.90e-06	322	43	7	int:H2BC12
Interaction	H1-5 interactions	H1-10 PUM3 TEX10 XIRP2 ALK BRD4 HIRA BMS1	5.23e-06	463	43	8	int:H1-5
Interaction	BAG2 interactions	DNAJB4 NCOA6 BRD3 EVC2 BRD2 ANKHD1 VPS13C BRD4 HIRA	5.29e-06	622	43	9	int:BAG2
Interaction	DOT1L interactions	H1-10 PUM3 MYBBP1A BRD3 TEX10 CDCA7L NOL8 MPRIP ZMYND8 BMS1	5.78e-06	807	43	10	int:DOT1L
Interaction	NOVA2 interactions	BRD3 BRD2 BRD4	6.03e-06	17	43	3	int:NOVA2
Interaction	PIP4K2A interactions	NOLC1 H1-10 BRD3 CCDC59 BRD2 BRD4	6.19e-06	216	43	6	int:PIP4K2A
Interaction	PWWP2B interactions	BRD3 BRD2 BRD4	7.22e-06	18	43	3	int:PWWP2B
Interaction	ERG interactions	NOLC1 NCOA6 BRD3 BRD2 UBR5 BRD4	7.43e-06	223	43	6	int:ERG
Interaction	KIF23 interactions	APC NOLC1 PUM3 MYBBP1A MYH11 UBR5 BRD4 CD2AP NOL8 MPRIP BMS1	7.56e-06	1031	43	11	int:KIF23
Interaction	SMARCA2 interactions	FAM184A MYBBP1A BRD3 BRD2 BRD4 HIRA MPRIP	7.84e-06	346	43	7	int:SMARCA2
Interaction	RCOR1 interactions	APC FAM193A ANKHD1 UBR5 BRD4 CD2AP EXOC4 ZMYND8	8.40e-06	494	43	8	int:RCOR1
Interaction	H1-2 interactions	H1-10 PUM3 BRD2 EP400 MAP4K5 BRD4 RBIS BMS1 SANBR	9.18e-06	666	43	9	int:H1-2
Interaction	DNAJC17 interactions	NOLC1 BRD2 BRD4 NOL8 BMS1	9.48e-06	134	43	5	int:DNAJC17
Interaction	CDC5L interactions	NOLC1 NRG1 MYBBP1A BRD2 TEX10 UBR5 BRD4 NOL8 EXOC4 BMS1	9.61e-06	855	43	10	int:CDC5L
Interaction	MECP2 interactions	APC NOLC1 MYBBP1A BRD3 BRD2 TEX10 EP400 BRD4 HIRA NOL8 ZMYND8 BMS1	1.05e-05	1287	43	12	int:MECP2
Interaction	RPS6 interactions	NOLC1 H1-10 PUM3 MYBBP1A BRD3 CCDC59 TEX10 BRD4 NOL8 BMS1	1.16e-05	874	43	10	int:RPS6
Interaction	CENPA interactions	H1-10 BRD3 BRD2 TEX10 HIRA NOL8 BMS1	1.37e-05	377	43	7	int:CENPA
Interaction	DHX40 interactions	BRD2 TEX10 UBR5 BRD4 NOL8 BMS1	1.39e-05	249	43	6	int:DHX40
Interaction	TP53BP1 interactions	NCOA6 TEX10 EP400 UBR5 BRD4 HIRA NOL8 EXOC4	1.46e-05	533	43	8	int:TP53BP1
Interaction	FGFBP1 interactions	PUM3 MYBBP1A TEX10 ANKHD1 NOL8 BMS1	1.67e-05	257	43	6	int:FGFBP1
Interaction	CSNK2A2 interactions	NOLC1 BRD3 CCDC59 PTPRC BRD2 TEX10 EP400 BRD4 ZMYND8	1.67e-05	718	43	9	int:CSNK2A2
Interaction	ZNF740 interactions	BRD3 BRD2 BRD4	2.01e-05	25	43	3	int:ZNF740
Interaction	CDC14B interactions	MYBBP1A BRD3 BRD2 TEX10 BMS1	2.10e-05	158	43	5	int:CDC14B
Interaction	PIP4K2C interactions	NOLC1 BRD3 CCDC59 BRD2 BRD4	2.17e-05	159	43	5	int:PIP4K2C
Interaction	SIRT7 interactions	NOLC1 H1-10 PUM3 MYBBP1A TEX10 ANKHD1 UBR5 BRD4 BMS1	2.22e-05	744	43	9	int:SIRT7
Interaction	CT45A5 interactions	NOLC1 BRD2 ANKHD1 BRD4	2.28e-05	78	43	4	int:CT45A5
Interaction	INO80E interactions	BRD3 BRD2 UBR5 CD2AP	2.40e-05	79	43	4	int:INO80E
Interaction	NEIL1 interactions	PUM3 MYBBP1A CCDC59 TEX10 ANKHD1 BMS1	2.49e-05	276	43	6	int:NEIL1
Interaction	CDX1 interactions	MYBBP1A ANKHD1 HIRA BMS1	2.53e-05	80	43	4	int:CDX1
Interaction	NOP2 interactions	NOLC1 PUM3 MYBBP1A CDCA7L BRD4 NOL8 BMS1	2.58e-05	416	43	7	int:NOP2
Interaction	ZNF592 interactions	BRD3 BRD2 BRD4 ZMYND8	2.65e-05	81	43	4	int:ZNF592
Interaction	RPL4 interactions	NOLC1 H1-10 PUM3 MYBBP1A BRD3 TEX10 BRD4 NOL8 BMS1	2.73e-05	764	43	9	int:RPL4
Interaction	FTSJ3 interactions	APC PUM3 MYBBP1A BRD3 CCDC59 VPS13C BRD4	2.82e-05	422	43	7	int:FTSJ3
Interaction	ABT1 interactions	PUM3 MYBBP1A TEX10 CDCA7L BRD4 NOL8 BMS1	2.87e-05	423	43	7	int:ABT1
Interaction	KLF16 interactions	NOLC1 H1-10 PUM3 MBTD1 MYBBP1A BRD2 EP400	2.95e-05	425	43	7	int:KLF16
Interaction	NPM1 interactions	DNAJB4 H1-10 PUM3 MYBBP1A BRD3 CCDC59 TEX10 ALK BRD4 ZMYND8 BMS1	3.16e-05	1201	43	11	int:NPM1
Interaction	ACTL6A interactions	MBTD1 BRD3 BRD2 EP400 UBR5 BRD4	3.22e-05	289	43	6	int:ACTL6A
Interaction	HECTD1 interactions	APC NOLC1 H1-10 PUM3 MYBBP1A CCDC59 TEX10 NOL8 EXOC4 BMS1	3.24e-05	984	43	10	int:HECTD1
Interaction	USP36 interactions	NOLC1 H1-10 PUM3 MYBBP1A CCDC59 TEX10 NOL8 BMS1	3.36e-05	599	43	8	int:USP36
Interaction	AR interactions	NCOA6 MYBBP1A BRD3 BRD2 EP400 UBR5 VPS13C BRD4 HIRA ZMYND8	3.47e-05	992	43	10	int:AR
Interaction	ARGLU1 interactions	NOLC1 DNAJB4 BRD3 UBR5 BRD4	3.53e-05	176	43	5	int:ARGLU1
Interaction	PDGFB interactions	PUM3 MYBBP1A TEX10 BMS1	3.68e-05	88	43	4	int:PDGFB
Interaction	RPL18A interactions	NOLC1 PUM3 MYBBP1A CCDC59 TEX10 BRD4 BMS1	4.07e-05	447	43	7	int:RPL18A
Interaction	RUVBL2 interactions	APC DNAJB4 MBTD1 BRD3 BRD2 EP400 UBR5 BRD4	4.10e-05	616	43	8	int:RUVBL2
Interaction	CTTN interactions	H1-10 ALK MAP4K5 BRD4 CD2AP HIRA MPRIP	4.25e-05	450	43	7	int:CTTN
Interaction	MED4 interactions	FAM184A BRD3 MYH11 UBR5 BRD4 CD2AP EXOC4	4.25e-05	450	43	7	int:MED4
Interaction	NUP43 interactions	APC H1-10 NCOA6 TEX10 EP400 UBR5 ZMYND8 BMS1	4.55e-05	625	43	8	int:NUP43
Interaction	CSNK2B interactions	APC NOLC1 BRD3 BRD2 EP400 BRD4 ZMYND8 BMS1	4.55e-05	625	43	8	int:CSNK2B
Interaction	SIRT6 interactions	APC PUM3 MYBBP1A TEX10 EP400 UBR5 BRD4 MPRIP	4.70e-05	628	43	8	int:SIRT6
Interaction	CTCF interactions	H1-10 PUM3 MYBBP1A BRD3 BRD2 BRD4 HIRA	4.95e-05	461	43	7	int:CTCF
Interaction	SMARCA4 interactions	MYBBP1A BRD3 BRD2 EP400 BRD4 HIRA ZMYND8	5.02e-05	462	43	7	int:SMARCA4
Interaction	ZNF711 interactions	BRD3 BRD2 BRD4	5.17e-05	34	43	3	int:ZNF711
Interaction	PIP4K2B interactions	BRD3 BRD2 CDCA7L BRD4	5.17e-05	96	43	4	int:PIP4K2B
Interaction	AKAP17A interactions	BRD3 BRD2 ANKHD1 UBR5	5.84e-05	99	43	4	int:AKAP17A
Interaction	PHIP interactions	NOLC1 BRD3 BRD2 ANKHD1 BRD4	6.04e-05	197	43	5	int:PHIP
Interaction	DENND2D interactions	NOLC1 BRD2 RBIS	6.15e-05	36	43	3	int:DENND2D
Interaction	UHRF2 interactions	NOLC1 MYBBP1A BRD3 PTPRC BRD4	6.49e-05	200	43	5	int:UHRF2
Interaction	BACC1 interactions	BRD3 BRD2 BRD4 CD2AP	7.07e-05	104	43	4	int:BACC1
Interaction	NUCB1 interactions	FAM184A BRD3 BRD2 BRD4	7.07e-05	104	43	4	int:NUCB1
Interaction	BANF1 interactions	BRD3 EVC2 BRD2 VPS13C BRD4	7.12e-05	204	43	5	int:BANF1
Interaction	PSIP1 interactions	BRD3 BRD2 CDCA7L BRD4 CD2AP	7.29e-05	205	43	5	int:PSIP1
Interaction	MED19 interactions	BRD3 BRD2 UBR5 BRD4	7.62e-05	106	43	4	int:MED19
Interaction	KMT5B interactions	BRD3 BRD2 BRD4	7.84e-05	39	43	3	int:KMT5B
Interaction	RRS1 interactions	NOLC1 PUM3 MYBBP1A BRD3 BRD4 BMS1	8.61e-05	345	43	6	int:RRS1
Interaction	RPL36 interactions	H1-10 PUM3 MYBBP1A TEX10 BRD4 NOL8 BMS1	8.67e-05	504	43	7	int:RPL36
Interaction	HDAC1 interactions	APC NOLC1 MYBBP1A ANKHD1 EP400 UBR5 BRD4 CD2AP EXOC4 ZMYND8	8.80e-05	1108	43	10	int:HDAC1
Interaction	LARP7 interactions	NOLC1 H1-10 PUM3 MYBBP1A BRD3 MYH11 BRD2 BRD4 CD2AP BMS1	9.14e-05	1113	43	10	int:LARP7
Interaction	TOP1 interactions	H1-10 NCOA6 BRD3 BRD2 EP400 UBR5 BRD4 ZMYND8	9.66e-05	696	43	8	int:TOP1
Interaction	HMGXB4 interactions	BRD3 BRD2 UBR5 BRD4	9.77e-05	113	43	4	int:HMGXB4
GeneFamily	Myosin heavy chains	MYH11 MYH13	1.91e-04	15	25	2	1098
Coexpression	SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN	NOLC1 NCOA6 MYBBP1A ANKHD1 TBC1D10A BRD4 CD2AP NOL8 MPRIP ZMYND8	3.32e-09	467	43	10	M1347
Coexpression	SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN	NOLC1 NCOA6 MYBBP1A ANKHD1 TBC1D10A BRD4 CD2AP NOL8 MPRIP ZMYND8	4.67e-09	484	43	10	MM999
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	APC NRG1 PUM3 FAM193A UBR5 MAP4K5 CD2AP HIRA ZMYND8	8.42e-06	856	43	9	M4500
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	NRG1 PUM3 UBR5 MAP4K5 CD2AP HIRA ZMYND8	9.95e-06	466	43	7	M13522
Coexpression	GSE6674_ANTI_IGM_VS_ANTI_IGM_AND_CPG_STIM_BCELL_DN	NOLC1 PUM3 MYBBP1A CDCA7L BMS1	1.83e-05	199	43	5	M6935
Coexpression	NAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_UP	APC NCOA6 CCDC59 TEX10 ANKHD1 UBR5 MAP4K5 NOL8 MPRIP ZMYND8	2.09e-05	1215	43	10	M41122
Coexpression	SHEN_SMARCA2_TARGETS_UP	APC NCOA6 ANKHD1 GIN1 MAP4K5 VPS13C	6.78e-05	429	43	6	M29
Coexpression	WELCSH_BRCA1_TARGETS_DN	NOLC1 H1-10 BRD2 BMS1	8.41e-05	141	43	4	M2428
Coexpression	SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX4_UP	NCOA6 ZMYND8	1.43e-04	11	43	2	M1358
Coexpression	SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX4_UP	NCOA6 ZMYND8	1.43e-04	11	43	2	MM569
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000	NOLC1 NRG1 PUM3 NCOA6 FAM184A FAM193A ANKHD1 UBR5 GIN1 CDCA7L NOL8 SANBR	2.95e-07	989	42	12	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	NCOA6 FAM184A MYNN FAM193A ANKHD1 UBR5 GIN1 NOL8 EXOC4 SANBR	3.76e-06	831	42	10	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#3	NOLC1 NRG1 PUM3 CDCA7L NOL8	2.02e-05	169	42	5	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K3
CoexpressionAtlas	dev gonad_e11.5_F_PrimGermCell_Oct_k-means-cluster#3_top-relative-expression-ranked_1000	NOLC1 PUM3 MYBBP1A TEX10 UBR5 NOL8 BMS1	3.12e-05	463	42	7	gudmap_dev gonad_e11.5_F_PrimGermCell_Oct_k3_1000
CoexpressionAtlas	dev gonad_e11.5_M_PrimGermCell_Oct_k-means-cluster#4_top-relative-expression-ranked_1000	NOLC1 PUM3 MYBBP1A TEX10 UBR5 NOL8	3.40e-05	315	42	6	gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_k4_1000
CoexpressionAtlas	dev gonad_e12.5_M_GermCellTestis_Oct_k-means-cluster#1_top-relative-expression-ranked_1000	NOLC1 PUM3 MYBBP1A TEX10 UBR5 NOL8	4.71e-05	334	42	6	gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_k1_1000
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#4_top-relative-expression-ranked_1000	PUM3 TEX10 UBR5 NOL8 BMS1	1.13e-04	243	42	5	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k4_1000
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3	APC NOLC1 NCOA6 FAM184A FAM193A TEX10 GIN1 BRD4 NOL8 SANBR	1.32e-04	1257	42	10	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlas	dev gonad_e12.5_M_GermCellTestis_Oct_top-relative-expression-ranked_1000	NOLC1 PUM3 MYBBP1A TEX10 UBR5 GIN1 NOL8 BMS1	1.42e-04	795	42	8	gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_1000
CoexpressionAtlas	FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_500_k-means-cluster#2	NOLC1 CDCA7L NOL8	2.76e-04	64	42	3	Facebase_RNAseq_e9.5_Maxillary Arch_500_K2
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	NCOA6 FAM184A FAM193A ANKHD1 GIN1	3.56e-04	311	42	5	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500	APC NOLC1 NCOA6 FAM184A FAM193A TEX10 GIN1 BRD4 NOL8 SANBR	4.40e-04	1459	42	10	facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlas	FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#3	NOLC1 NRG1 CDCA7L NOL8	4.53e-04	182	42	4	Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	UBR5 GIN1 VPS13C NOL8 SANBR	4.54e-04	328	42	5	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K2
CoexpressionAtlas	FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#3	NOLC1 CDCA7L NOL8	6.79e-04	87	42	3	Facebase_RNAseq_e9.5_Maxillary Arch_1000_K3
CoexpressionAtlas	DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#5_top-relative-expression-ranked_1000	APC MBTD1 MYNN CD2AP	6.83e-04	203	42	4	gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000_k5
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APC PTPRC VPS13C CD2AP	2.95e-05	184	43	4	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-intestinal_crypt_stem_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NOLC1 PUM3 MYBBP1A VPS13C	3.34e-05	190	43	4	52c59001a079c76249abbaa3141e9e661b83d9a0
ToppCell	facs-Thymus-nan-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MBTD1 PTPRC VPS13C MPRIP	3.55e-05	193	43	4	a6a864644e1b80b7417ea0a27281e79068a3fd3d
ToppCell	COVID-19_Severe-PLT_4\|COVID-19_Severe / Disease Group and Platelet Clusters	MBTD1 XIRP2 MAP4K5 RBIS	3.93e-05	198	43	4	abfddbee99ef8c7719e6e6f62571e9be030e4acf
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	MAP4K5 VPS13C BRD4 CD2AP	3.93e-05	198	43	4	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	MAP4K5 VPS13C BRD4 CD2AP	4.00e-05	199	43	4	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	(04)_Interm._basal>secr.-(2)_GFP_FOXI1\|(04)_Interm._basal>secr. / shred by cell type by condition	MAP4K5 VPS13C BRD4 CD2AP	4.00e-05	199	43	4	53ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	MAP4K5 VPS13C BRD4 CD2AP	4.00e-05	199	43	4	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
Drug	OTX015	BRD3 BRD2 BRD4	3.45e-06	16	43	3	ctd:C000605331
Disease	Childhood Medulloblastoma	APC BRD3 BRD2 BRD4	4.20e-07	43	42	4	C0278510
Disease	Melanotic medulloblastoma	APC BRD3 BRD2 BRD4	4.20e-07	43	42	4	C1275668
Disease	Medullomyoblastoma	APC BRD3 BRD2 BRD4	4.20e-07	43	42	4	C0205833
Disease	Desmoplastic Medulloblastoma	APC BRD3 BRD2 BRD4	4.20e-07	43	42	4	C0751291
Disease	Adult Medulloblastoma	APC BRD3 BRD2 BRD4	4.20e-07	43	42	4	C0278876
Disease	Medulloblastoma	APC BRD3 BRD2 BRD4	7.78e-07	50	42	4	C0025149
Disease	fasting blood glucose measurement, glucose tolerance test, fasting blood insulin measurement	MAP4K5 VPS13C	1.97e-05	5	42	2	EFO_0004307, EFO_0004465, EFO_0004466
Disease	platelet component distribution width	BRD3 PTPRC MYH13 TBC1D10A CD2AP MPRIP ZMYND8	8.64e-05	755	42	7	EFO_0007984
Disease	schizophrenia, intelligence, self reported educational attainment	DNAJB4 FAM184A BRD3 MYH11 EXOC4	1.28e-04	346	42	5	EFO_0004337, EFO_0004784, MONDO_0005090
Disease	distal myopathy (implicated_via_orthology)	DNAJB4 MYH13	1.29e-04	12	42	2	DOID:11720 (implicated_via_orthology)
Disease	Glioblastoma	APC BRD2 BRD4	1.97e-04	79	42	3	C0017636
Disease	Giant Cell Glioblastoma	APC BRD2 BRD4	2.36e-04	84	42	3	C0334588
Disease	Benign neoplasm of stomach	APC UBR5	2.65e-04	17	42	2	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	APC UBR5	2.65e-04	17	42	2	C0496905
Disease	Carcinoma in situ of stomach	APC UBR5	2.65e-04	17	42	2	C0154060
Disease	Stomach Carcinoma	APC UBR5	4.08e-04	21	42	2	C0699791
Disease	Glioblastoma Multiforme	APC BRD2 BRD4	5.34e-04	111	42	3	C1621958
Disease	mean platelet volume	BRD3 MYH11 PTPRC MAP4K5 CD2AP MPRIP ZMYND8	5.41e-04	1020	42	7	EFO_0004584
Disease	immature platelet fraction	BRD3 CD2AP ZMYND8	5.78e-04	114	42	3	EFO_0009187
Disease	eosinophil percentage of leukocytes	BRD3 MYNN FAM193A PTPRC MAP4K5 ZMYND8	6.18e-04	746	42	6	EFO_0007991
Disease	immature platelet measurement	BRD3 CD2AP ZMYND8	6.55e-04	119	42	3	EFO_0803541
Disease	glucose tolerance test	MAP4K5 VPS13C	6.79e-04	27	42	2	EFO_0004307
Disease	mean corpuscular hemoglobin concentration	BRD3 MYNN PTPRC EP400 UBR5 MAP4K5 BRD4	8.68e-04	1105	42	7	EFO_0004528
Disease	melanoma (is_marker_for)	BRD2 BRD4	1.02e-03	33	42	2	DOID:1909 (is_marker_for)
Disease	Neoplastic Cell Transformation	APC NRG1 ALK	1.03e-03	139	42	3	C0007621
Disease	colon cancer (is_implicated_in)	NCOA6 BRD4	1.21e-03	36	42	2	DOID:219 (is_implicated_in)
Disease	red blood cell density measurement	NRG1 PTPRC EP400 UBR5 MAP4K5 BRD4	1.45e-03	880	42	6	EFO_0007978
Disease	response to simvastatin, myopathy	EVC2 ALK	1.57e-03	41	42	2	EFO_0004145, GO_1903491
Disease	Prostatic Neoplasms	APC MYBBP1A PTPRC BRD4 NOL8	1.75e-03	616	42	5	C0033578
Disease	Malignant neoplasm of prostate	APC MYBBP1A PTPRC BRD4 NOL8	1.75e-03	616	42	5	C0376358
Disease	Gastric Adenocarcinoma	BRD3 BRD2	1.88e-03	45	42	2	C0278701
Disease	lung adenocarcinoma	DNAJB4 NRG1 MYNN	1.95e-03	174	42	3	EFO_0000571
Disease	lean body mass	DNAJB4 TEX10 MAP4K5 VPS13C	2.04e-03	379	42	4	EFO_0004995
Disease	cholesteryl ester 20:3 measurement	FAM184A MYH11	2.23e-03	49	42	2	EFO_0010347
Disease	serum selenium measurement	NRG1 PUM3	2.60e-03	53	42	2	EFO_0005266

Protein segments in the cluster

Peptide	Gene	Start	Entry
KKNILLKQQVPFAKP	EP400	2336	Q96L91
PAKQAQQKKAPAKKA	BRD3	526	Q15059
AALSQPQQNKPKKKE	BRD4	526	O60885
KEPPPKKTKKNNSSN	BRD4	566	O60885
QPHPQTKNIKKKTKK	CD2AP	96	Q9Y5K6
QKALPFKNKPKTQAK	BMS1	1171	Q14692
FKNKPKTQAKAGKVP	BMS1	1176	Q14692
LAESPQPKGKNKKNK	FAM193A	1141	P78312
INPLAKQKKKNDKSP	FAM184A	1041	Q8NB25
QKKQPVQKGVKPQAK	NOLC1	141	Q14978
KKIKLQTPNTFPKRK	NOLC1	601	Q14978
KSPKNKFQPANKFNK	PUM3	76	Q15397
NKPQNIKIQKKPGKS	NRG1	81	Q02297
NNLKPSKKKLGQHYK	KIAA0100	1306	Q14667
TNKQNQKKKRKVEPP	MPRIP	151	Q6WCQ1
QGKPPTKKAKVLQKQ	MBTD1	96	Q05BQ5
SPSKKRKNSKKKNQP	H1-10	31	Q92522
KKKKAFNSPKTGQNK	MYNN	181	Q9NPC7
HVPPRKKKNFLNAKK	EVC2	1286	Q86UK5
FQFPTKKLANKPDKN	CDCA7L	146	Q96GN5
CGKQKPKENNLKPKF	NOL8	556	Q76FK4
PKENNLKPKFQAFKG	NOL8	561	Q76FK4
AKSPKLQKKNQKPSQ	MYBBP1A	1246	Q9BQG0
QNNTNANKPKKKKPP	NCOA6	906	Q14686
KKKPQRPKNSLFKFE	EXOC4	431	Q96A65
KQALKFHPDKNKSPQ	DNAJB4	26	Q9UDY4
FNPKIFKKKQKNGSS	HIRA	276	P54198
PIKKKKKPGLLNSNN	ZMYND8	41	Q9ULU4
KQRQTRQFKSKPPKK	PDE6G	31	P18545
SKSNFQPPKLKDKTK	MAP4K5	231	Q9Y4K4
QNAPKPDKKIVSKLK	SNX25	466	Q9H3E2
IVKKKPKQLNPFHLK	GIN1	351	Q9NXP7
VFKILNKKTKKGQPN	CCDC59	211	Q9P031
KPKKFTRQPKKQVSS	SANBR	586	Q6NSI8
KNFKAKNKAKPVTTN	RBIS	21	Q8N0T1
QLNSTKKPPKKANEK	BRD2	746	P25440
FTEKPTKKNNPIAKK	ALK	1511	Q9UM73
TNRKNKKNKTKETPP	ANKHD1	1541	Q8IWZ3
NKNQLDGKKKKPTSP	APC	1761	P25054
PKFQKPKQLKDKTEF	MYH11	561	P35749
KPKLPKHIKDNKNDF	XIRP2	2251	A4UGR9
KSNNFQKPKPAKGKA	MYH13	561	Q9UKX3
KKPKLQNATPTNFKT	TEX10	21	Q9NXF1
VKPKQKWKPFSQKQI	VPS13C	3121	Q709C8
SKAKPKPPKQAQKEQ	TBC1D10A	421	Q9BXI6
KFPIKEARKPFNQNK	PTPRC	666	P08575
SKKKNNFIPQPIGKC	UBR5	1446	O95071
KKGKNQKVLSKNLNP	ZNF311	216	Q5JNZ3