Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstructural constituent of nuclear pore

NUP98 NUP214 NUP58

2.54e-0525463GO:0017056
GeneOntologyMolecularFunctionnuclear localization sequence binding

NUP98 NUP214 NUP58

3.22e-0527463GO:0008139
GeneOntologyMolecularFunctionsignal sequence binding

NUP98 NUP214 NUP58

2.21e-0451463GO:0005048
GeneOntologyBiologicalProcessrespiratory system development

MUC19 CLDN18 MYOCD EYA1 MAN2A1 CIC MYT1

6.32e-06305487GO:0060541
GeneOntologyBiologicalProcesstube development

GREB1L MUC19 CLDN18 NUP50 MYOCD EYA1 DLC1 MAN2A1 PTPRM BECN1 JMJD1C CIC JAG1

1.28e-0514024813GO:0035295
GeneOntologyBiologicalProcessimmunoglobulin production

IGKV1-16 IGLV2-23 IGLV2-14 IGLV5-45 IGLV5-39 MCM3AP

1.95e-05241486GO:0002377
GeneOntologyBiologicalProcessmRNA transport

NUP98 NUP50 NUP214 NUP58 MCM3AP

2.15e-05145485GO:0051028
GeneOntologyBiologicalProcesslung alveolus development

CLDN18 MYOCD MAN2A1 CIC

2.78e-0575484GO:0048286
GeneOntologyBiologicalProcesslung development

MUC19 CLDN18 MYOCD EYA1 MAN2A1 CIC

3.61e-05269486GO:0030324
GeneOntologyBiologicalProcessproduction of molecular mediator of immune response

IGKV1-16 IGLV2-23 IGLV2-14 IL31RA IGLV5-45 IGLV5-39 MCM3AP

3.81e-05403487GO:0002440
GeneOntologyBiologicalProcessrespiratory tube development

MUC19 CLDN18 MYOCD EYA1 MAN2A1 CIC

3.92e-05273486GO:0030323
GeneOntologyBiologicalProcessRNA transport

NUP98 NUP50 NUP214 NUP58 MCM3AP

5.29e-05175485GO:0050658
GeneOntologyBiologicalProcessnucleic acid transport

NUP98 NUP50 NUP214 NUP58 MCM3AP

5.29e-05175485GO:0050657
GeneOntologyBiologicalProcessestablishment of RNA localization

NUP98 NUP50 NUP214 NUP58 MCM3AP

5.74e-05178485GO:0051236
GeneOntologyBiologicalProcessRNA localization

NUP98 NUP50 NUP214 NUP58 MCM3AP

1.46e-04217485GO:0006403
GeneOntologyBiologicalProcessnucleobase-containing compound transport

NUP98 NUP50 NUP214 NUP58 MCM3AP

2.76e-04249485GO:0015931
GeneOntologyCellularComponentnuclear pore

NUP98 NUP50 NUP214 NUP58 MCM3AP

3.46e-06101485GO:0005643
GeneOntologyCellularComponentimmunoglobulin complex

IGKV1-16 IGLV2-23 IGLV2-14 IGLV5-45 IGLV5-39

3.86e-05166485GO:0019814
GeneOntologyCellularComponentnuclear pore nuclear basket

NUP98 MCM3AP

7.72e-0418482GO:0044615
DomainVWC_out

MUC19 JAG1

8.64e-0419432SM00215
DomainVWC

MUC19 JAG1

3.45e-0338432SM00214
DomainVWF_dom

MUC19 JAG1

4.20e-0342432IPR001007
PathwayREACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN

NUP98 NUP50 NUP214 NUP58

2.30e-0632424M29579
PathwayREACTOME_ISG15_ANTIVIRAL_MECHANISM

NUP98 NUP50 NUP214 NUP58 BECN1

2.54e-0674425M48006
PathwayREACTOME_EXPORT_OF_VIRAL_RIBONUCLEOPROTEINS_FROM_NUCLEUS

NUP98 NUP50 NUP214 NUP58

2.62e-0633424M27016
PathwayREACTOME_NUCLEAR_IMPORT_OF_REV_PROTEIN

NUP98 NUP50 NUP214 NUP58

2.96e-0634424M27041
PathwayREACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS

NUP98 NUP50 NUP214 NUP58

3.33e-0635424M27320
PathwayREACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY

NUP98 NUP50 NUP214 NUP58

3.74e-0636424M27245
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

NUP98 NUP50 NUP214 NUP58

3.74e-0636424M26974
PathwayREACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS

NUP98 NUP50 NUP214 NUP58

4.19e-0637424M1029
PathwayREACTOME_INTERACTIONS_OF_REV_WITH_HOST_CELLULAR_PROTEINS

NUP98 NUP50 NUP214 NUP58

4.19e-0637424M27038
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

NUP98 NUP50 NUP214 NUP58

5.19e-0639424M27238
PathwayREACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY

NUP98 NUP50 NUP214 NUP58

5.75e-0640424MM14945
PathwayREACTOME_NS1_MEDIATED_EFFECTS_ON_HOST_PATHWAYS

NUP98 NUP50 NUP214 NUP58

6.36e-0641424M29574
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

NUP98 NUP50 NUP214 NUP58

6.36e-0641424MM15200
PathwayREACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS

NUP98 NUP50 NUP214 NUP58

7.02e-0642424MM15039
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

NUP98 NUP50 NUP214 NUP58

7.72e-0643424MM14609
PathwayREACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS

NUP98 NUP50 NUP214 NUP58

7.72e-0643424M26975
PathwayREACTOME_SARS_COV_INFECTIONS

NUP98 IGKV1-16 NUP50 IGLV2-23 IGLV2-14 NUP214 NUP58 MAN2A1 BECN1

8.02e-06471429M39009
PathwayREACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS

NUP98 NUP50 NUP214 NUP58

8.47e-0644424M109
PathwayREACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS

NUP98 NUP50 NUP214 NUP58

1.01e-0546424M27397
PathwayREACTOME_SLC_TRANSPORTER_DISORDERS

NUP98 NUP50 NUP214 NUP58 SLC20A2

1.07e-0599425M27474
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

NUP98 NUP50 NUP214 NUP58

1.11e-0547424MM14939
PathwayREACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS

NUP98 NUP50 NUP214 NUP58

1.11e-0547424M27395
PathwayREACTOME_GENE_SILENCING_BY_RNA

NUP98 NUP50 NUP214 NUP58

1.31e-0549424MM14837
PathwayREACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS

NUP98 NUP50 NUP214 NUP58

1.42e-0550424MM14610
PathwayREACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS

NUP98 NUP50 NUP214 NUP58

1.54e-0551424MM15151
PathwayREACTOME_NUCLEAR_ENVELOPE_BREAKDOWN

NUP98 NUP50 NUP214 NUP58

1.79e-0553424M27212
PathwayREACTOME_SNRNP_ASSEMBLY

NUP98 NUP50 NUP214 NUP58

1.93e-0554424M29594
PathwayREACTOME_NUCLEAR_ENVELOPE_BREAKDOWN

NUP98 NUP50 NUP214 NUP58

2.08e-0555424MM14917
PathwayREACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS

NUP98 NUP50 NUP214 NUP58

2.57e-0558424MM15149
PathwayREACTOME_SNRNP_ASSEMBLY

NUP98 NUP50 NUP214 NUP58

2.57e-0558424MM14736
PathwayREACTOME_TRNA_PROCESSING_IN_THE_NUCLEUS

NUP98 NUP50 NUP214 NUP58

2.75e-0559424M27606
PathwayREACTOME_SARS_COV_2_ACTIVATES_MODULATES_INNATE_AND_ADAPTIVE_IMMUNE_RESPONSES

NUP98 NUP50 NUP214 NUP58 BECN1

3.44e-05126425M45009
PathwayREACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS

NUP98 NUP50 NUP214 NUP58

4.04e-0565424MM15147
PathwayREACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS

NUP98 NUP50 NUP214 NUP58

5.72e-0571424M27394
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

NUP98 NUP50 NUP214 NUP58

6.38e-0573424MM14948
PathwayREACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS

NUP98 NUP50 NUP214 NUP58

7.87e-0577424M27226
PathwayREACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES

NUP98 NUP50 NUP214 NUP58 BECN1

8.15e-05151425M550
PathwayREACTOME_GLUCOSE_METABOLISM

NUP98 NUP50 NUP214 NUP58

1.01e-0482424MM15394
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

NUP98 NUP50 NUP214 NUP58

1.01e-0482424M27250
PathwayREACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS

NUP98 NUP50 NUP214 NUP58

1.10e-0484424MM14929
PathwayREACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM

NUP98 NUP50 NUP214 NUP58

1.10e-0484424M725
PathwayREACTOME_GLUCOSE_METABOLISM

NUP98 NUP50 NUP214 NUP58

1.16e-0485424M1870
PathwayREACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM

NUP98 NUP50 NUP214 NUP58

1.21e-0486424MM15413
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

NUP98 NUP50 NUP214 NUP58

1.57e-0492424MM14951
PathwayREACTOME_DISORDERS_OF_TRANSMEMBRANE_TRANSPORTERS

NUP98 NUP50 NUP214 NUP58 SLC20A2

1.72e-04177425M27476
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

NUP98 NUP50 NUP214 NUP58

2.25e-04101424M27253
PathwayREACTOME_SARS_COV_2_INFECTION

NUP98 NUP50 NUP214 NUP58 MAN2A1 BECN1

2.39e-04299426M41727
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

NUP98 NUP50 NUP214 NUP58

2.71e-04106424M27458
PathwayWP_PRADERWILLI_AND_ANGELMAN_SYNDROME

NUP98 NUP50 NUP214 NUP58

3.02e-04109424M39542
PathwayREACTOME_TRNA_PROCESSING

NUP98 NUP50 NUP214 NUP58

3.24e-04111424M27684
PathwayREACTOME_SARS_COV_2_HOST_INTERACTIONS

NUP98 NUP50 NUP214 NUP58 BECN1

3.33e-04204425M45011
PathwayREACTOME_MITOTIC_PROPHASE

NUP98 NUP50 NUP214 NUP58

3.58e-04114424MM15361
PathwayREACTOME_HCMV_LATE_EVENTS

NUP98 NUP50 NUP214 NUP58

3.83e-04116424M29806
PathwayREACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS

NUP98 NUP50 NUP214 NUP58

6.06e-04131424M5283
PathwayREACTOME_HCMV_EARLY_EVENTS

NUP98 NUP50 NUP214 NUP58

7.37e-04138424M29805
PathwayREACTOME_GENE_SILENCING_BY_RNA

NUP98 NUP50 NUP214 NUP58

7.58e-04139424M715
PathwayREACTOME_CD22_MEDIATED_BCR_REGULATION

IGKV1-16 IGLV2-23 IGLV2-14

7.85e-0461423M27581
PathwayREACTOME_MITOTIC_PROPHASE

NUP98 NUP50 NUP214 NUP58

8.21e-04142424M27660
PathwayREACTOME_HIV_LIFE_CYCLE

NUP98 NUP50 NUP214 NUP58

9.82e-04149424M4076
PathwayREACTOME_VIRAL_INFECTION_PATHWAYS

NUP98 IGKV1-16 NUP50 IGLV2-23 IGLV2-14 NUP214 NUP58 MAN2A1 BECN1

1.01e-03888429M48034
PathwayREACTOME_FCGR_ACTIVATION

IGKV1-16 IGLV2-23 IGLV2-14

1.12e-0369423M27108
PathwayREACTOME_SCAVENGING_OF_HEME_FROM_PLASMA

IGKV1-16 IGLV2-23 IGLV2-14

1.12e-0369423M27150
PathwayREACTOME_INFLUENZA_INFECTION

NUP98 NUP50 NUP214 NUP58

1.19e-03157424M4669
PathwayREACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS

IGKV1-16 IGLV2-23 IGLV2-14

1.22e-0371423M1078
PathwayREACTOME_ROLE_OF_LAT2_NTAL_LAB_ON_CALCIUM_MOBILIZATION

IGKV1-16 IGLV2-23 IGLV2-14

1.22e-0371423M27203
PathwayREACTOME_INTERFERON_SIGNALING

NUP98 NUP50 NUP214 NUP58 BECN1

1.24e-03273425M983
PathwayWP_NEPHROGENESIS

GREB1L JAG1

1.29e-0318422M40045
PathwayREACTOME_HCMV_INFECTION

NUP98 NUP50 NUP214 NUP58

1.34e-03162424M29804
PathwayREACTOME_SUMOYLATION

NUP98 NUP50 NUP214 NUP58

1.56e-03169424MM14919
PathwayREACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT

IGKV1-16 IGLV2-23 IGLV2-14

1.72e-0380423M6121
PathwayREACTOME_ROLE_OF_PHOSPHOLIPIDS_IN_PHAGOCYTOSIS

IGKV1-16 IGLV2-23 IGLV2-14

1.85e-0382423M27110
PathwayREACTOME_FCERI_MEDIATED_CA_2_MOBILIZATION

IGKV1-16 IGLV2-23 IGLV2-14

2.12e-0386423M27206
PathwayREACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_BCR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS

IGKV1-16 IGLV2-23 IGLV2-14

2.12e-0386423M601
PathwayREACTOME_FCERI_MEDIATED_MAPK_ACTIVATION

IGKV1-16 IGLV2-23 IGLV2-14

2.19e-0387423M27205
PathwayREACTOME_SUMOYLATION

NUP98 NUP50 NUP214 NUP58

2.35e-03189424M27214
PathwayREACTOME_FCGR3A_MEDIATED_IL10_SYNTHESIS

IGKV1-16 IGLV2-23 IGLV2-14

2.81e-0395423M29842
PathwayREACTOME_POSTMITOTIC_NUCLEAR_PORE_COMPLEX_NPC_REFORMATION

NUP98 NUP58

2.90e-0327422M29807
PathwayREACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS

IGKV1-16 IGLV2-23 IGLV2-14

3.07e-0398423M27152
PathwayKEGG_MEDICUS_REFERENCE_NUCLEAR_EXPORT_OF_MRNA

NUP214 NUP58

3.58e-0330422M47752
PathwayREACTOME_INFECTIOUS_DISEASE

NUP98 IGKV1-16 NUP50 IGLV2-23 IGLV2-14 NUP214 NUP58 MAN2A1 BECN1

3.93e-031081429M27548
PathwayREACTOME_COMPLEMENT_CASCADE

IGKV1-16 IGLV2-23 IGLV2-14

4.82e-03115423M19752
PathwayREACTOME_HIV_INFECTION

NUP98 NUP50 NUP214 NUP58

4.83e-03231424M12469
PathwayREACTOME_PARASITE_INFECTION

IGKV1-16 IGLV2-23 IGLV2-14

4.93e-03116423M29843
PathwayREACTOME_ANTI_INFLAMMATORY_RESPONSE_FAVOURING_LEISHMANIA_PARASITE_INFECTION

IGKV1-16 IGLV2-23 IGLV2-14

7.36e-03134423M29840
PathwayREACTOME_INTRA_GOLGI_TRAFFIC

NAPA MAN2A1

7.57e-0344422M27652
PathwayREACTOME_FCERI_MEDIATED_NF_KB_ACTIVATION

IGKV1-16 IGLV2-23 IGLV2-14

7.66e-03136423M27207
PathwayREACTOME_KIDNEY_DEVELOPMENT

EYA1 JAG1

8.25e-0346422M48243
PathwayPID_RHOA_REG_PATHWAY

MCF2 DLC1

8.25e-0346422M68
PathwayREACTOME_METABOLISM_OF_CARBOHYDRATES

NUP98 NUP50 NUP214 NUP58

8.43e-03271424MM15406
PathwayREACTOME_CELL_CYCLE

NUP98 NUP50 NUP214 NUP58 POLE2 PIF1

8.44e-03603426MM14635
Pubmed

Probing nuclear pore complex architecture with proximity-dependent biotinylation.

NUP98 NUP50 NUP214 NUP58 CSMD3 MCM3AP

1.10e-097748624927568
Pubmed

Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein, whereas export is due to a nuclear export signal sequence in glucokinase.

NUP98 NUP50 NUP214 NUP58

3.95e-082548410601273
Pubmed

Docking of HIV-1 Vpr to the nuclear envelope is mediated by the interaction with the nucleoporin hCG1.

NUP98 NUP50 NUP214 NUP58

4.67e-082648412228227
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

NUP98 NAPA NUP50 NUP214 NUP58 JMJD1C CIC MCM3AP

1.99e-0745748832344865
Pubmed

Peering through the pore: nuclear pore complex structure, assembly, and function.

NUP98 NUP50 NUP214 NUP58

2.28e-073848412791264
Pubmed

Phase-separated nuclear bodies of nucleoporin fusions promote condensation of MLL1/CRM1 and rearrangement of 3D genome structure.

NUP98 NUP50 NUP214 NUP58

2.81e-074048437516964
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

NUP98 MUC19 NUP50 NUP214 JMJD1C

7.73e-0712348526912792
Pubmed

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

NUP98 NUP50 NUP58 JMJD1C MCM3AP

5.02e-0618048535198878
Pubmed

Nucleoporins nup98 and nup214 participate in nuclear export of human immunodeficiency virus type 1 Rev.

NUP98 NUP214

5.59e-0634829847314
Pubmed

Notch signaling represses myocardin-induced smooth muscle cell differentiation.

MYOCD JAG1

5.59e-06348215634680
Pubmed

Nup98 localizes to both nuclear and cytoplasmic sides of the nuclear pore and binds to two distinct nucleoporin subcomplexes.

NUP98 NUP214

5.59e-06348212589057
Pubmed

Myocardin/microRNA-30a/Beclin1 signaling controls the phenotypic modulation of vascular smooth muscle cells by regulating autophagy.

MYOCD BECN1

5.59e-06348235136037
Pubmed

The nuclear pore complex: a new dynamic in HIV-1 replication.

NUP98 NUP214

5.59e-06348221327100
Pubmed

A role for nucleoporin FG repeat domains in export of human immunodeficiency virus type 1 Rev protein and RNA from the nucleus.

NUP98 NUP214

5.59e-0634828943370
Pubmed

Nup50 is required for cell differentiation and exhibits transcription-dependent dynamics.

NUP98 NUP50

5.59e-06348224943837
Pubmed

Integrated structural analysis of the human nuclear pore complex scaffold.

NUP50 NUP214 NUP58

9.76e-063048324315095
Pubmed

The Structure Inventory of the Nuclear Pore Complex.

NUP50 NUP214 NUP58

9.76e-063048327016207
Pubmed

In vitro analysis of nuclear transport mediated by the C-terminal shuttle domain of Tap.

NUP98 NUP214

1.12e-05448211551912
Pubmed

The importin-beta family member Crm1p bridges the interaction between Rev and the nuclear pore complex during nuclear export.

NUP98 NUP214

1.12e-0544829368759
Pubmed

Biallelic mutations in nucleoporin NUP88 cause lethal fetal akinesia deformation sequence.

NUP98 NUP214

1.12e-05448230543681
Pubmed

Nuclear pore composition regulates neural stem/progenitor cell differentiation in the mouse embryo.

NUP98 NUP50 NUP214

1.43e-053448318539113
Pubmed

Oxidative stress inhibits nuclear protein export by multiple mechanisms that target FG nucleoporins and Crm1.

NUP98 NUP214

1.86e-05548219828735
Pubmed

A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells.

NUP98 NUP50 NUP214 MCM3AP

2.41e-0512148422412018
Pubmed

Karyopherin beta2 mediates nuclear import of a mRNA binding protein.

NUP98 NUP214

2.79e-0564829144189
Pubmed

Cessation of HIV-1 transcription by inhibiting regulatory protein Rev-mediated RNA transport.

NUP98 NUP214

2.79e-05648219149559
Pubmed

Activation of C1r by proteolytic cleavage.

IGLV2-23 IGLV2-14 IGLV5-45

2.93e-05434831249422
Pubmed

Physicochemical and functional characterization of the C1r subunit of the first complement component.

IGLV2-23 IGLV2-14 IGLV5-45

3.83e-0547483814163
Pubmed

Notch1 haploinsufficiency causes ascending aortic aneurysms in mice.

MYOCD JAG1

3.90e-05748229093270
Pubmed

Direct interaction with nup153 mediates binding of Tpr to the periphery of the nuclear pore complex.

NUP98 NUP50

3.90e-05748212802065
Pubmed

Cofactor requirements for nuclear export of Rev response element (RRE)- and constitutive transport element (CTE)-containing retroviral RNAs. An unexpected role for actin.

NUP98 NUP214

3.90e-05748211238447
Pubmed

Recognition of immunoglobulins by Fcgamma receptors.

IGLV2-23 IGLV2-14 IGLV5-45

4.08e-054848311955599
Pubmed

Sequence and evolution of the human germline V lambda repertoire.

IGLV2-14 IGLV5-45 IGLV5-39

4.35e-05494838951372
Pubmed

Imaging within single NPCs reveals NXF1's role in mRNA export on the cytoplasmic side of the pore.

NUP98 NUP214

5.19e-05848231375530
Pubmed

Endothelial Notch activity promotes angiogenesis and osteogenesis in bone.

MCF2 JAG1

5.19e-05848224647000
Pubmed

A tissue-specific, Gata6-driven transcriptional program instructs remodeling of the mature arterial tree.

MYOCD JAG1

5.19e-05848228952437
Pubmed

Cloning and characterization of human karyopherin beta3.

NUP98 NUP214

6.67e-0594829114010
Pubmed

Pax2 and Pax8 cooperate in mouse inner ear morphogenesis and innervation.

EYA1 JAG1

6.67e-05948220727173
Pubmed

Nuclear import of the glucocorticoid receptor-hsp90 complex through the nuclear pore complex is mediated by its interaction with Nup62 and importin beta.

NUP98 NUP214

8.33e-051048219581287
Pubmed

Crosstalk between Jagged1 and GDNF/Ret/GFRalpha1 signalling regulates ureteric budding and branching.

EYA1 JAG1

8.33e-051048215905075
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

NUP98 NUP50 NUP214 NUP58 MCM3AP

9.41e-0533248525693804
Pubmed

Lack of pendrin expression leads to deafness and expansion of the endolymphatic compartment in inner ears of Foxi1 null mutant mice.

EYA1 JAG1

1.02e-041148212642503
Pubmed

Osr1 acts downstream of and interacts synergistically with Six2 to maintain nephron progenitor cells during kidney organogenesis.

EYA1 JAG1

1.22e-041248224598167
Pubmed

Interaction network of human early embryonic transcription factors.

NUP98 RLF NUP214 NUP58 MCM3AP

1.22e-0435148538297188
Pubmed

TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture.

NUP98 NUP214

1.68e-041448211073998
Pubmed

Mutations in Hnrnpa1 cause congenital heart defects.

MYOCD JAG1

2.21e-041648229367466
Pubmed

The role of Pax2 in mouse inner ear development.

EYA1 JAG1

2.50e-041748215242798
Pubmed

The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates.

NUP98 NUP214

2.50e-041748210668806
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

GREB1L RLF NUP214 JMJD1C CIC

2.74e-0441848534709266
Pubmed

Negative regulation of endothelin signaling by SIX1 is required for proper maxillary development.

EYA1 JAG1

2.81e-041848228455376
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

NUP98 NUP214 UBQLN2 CIC SH3D21

3.12e-0443048535044719
Pubmed

Stromally expressed β-catenin modulates Wnt9b signaling in the ureteric epithelium.

EYA1 JAG1

3.49e-042048225803581
Pubmed

ISL1 and POU4F1 Directly Interact to Regulate the Differentiation and Survival of Inner Ear Sensory Neurons.

EYA1 MYT1

3.49e-042048238267260
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

NUP214 UBQLN2 JMJD1C CIC

3.50e-0424248434011540
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

NUP98 SEMG1 NUP50 NUP214 EYA1 PTPRM POLE2

3.58e-0497448728675297
Pubmed

Fibroblast growth factor receptor-Frs2α signaling is critical for nephron progenitors.

EYA1 JAG1

4.23e-042248225641696
Pubmed

An Eya1-Notch axis specifies bipotential epibranchial differentiation in mammalian craniofacial morphogenesis.

EYA1 JAG1

4.23e-042248229140246
Pubmed

Notch signalling regulates epibranchial placode patterning and segregation.

EYA1 JAG1

4.63e-042348231988190
Pubmed

Msx genes define a population of mural cell precursors required for head blood vessel maturation.

MYOCD JAG1

4.63e-042348221693521
Pubmed

One-megabase sequence analysis of the human immunoglobulin lambda gene locus.

IGLV2-23 IGLV2-14 IGLV5-45

4.67e-041094839074928
Pubmed

Von Hippel-Lindau Acts as a Metabolic Switch Controlling Nephron Progenitor Differentiation.

EYA1 JAG1

5.05e-042448231142573
Pubmed

Hemodynamic force is required for vascular smooth muscle cell recruitment to blood vessels during mouse embryonic development.

MYOCD JAG1

5.05e-042448230796970
Pubmed

Continued expression of GATA3 is necessary for cochlear neurosensory development.

EYA1 JAG1

5.05e-042448223614009
Pubmed

A human MAP kinase interactome.

NUP98 NUP214 NUP58 CIC MCM3AP

5.45e-0448648520936779
Pubmed

Genomic architecture of Shh-dependent cochlear morphogenesis.

EYA1 JAG1

6.89e-042848231488567
Pubmed

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.

NUP98 NUP214 NUP58 AASS

7.64e-0429848432353859
Pubmed

Recapitulating early development of mouse musculoskeletal precursors of the paraxial mesoderm in vitro.

GREB1L MYOCD

7.92e-043048229555813
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZNF704 ZNF300 ZNF397 NFAT5 CIC MYT1

8.25e-0480848620412781
Pubmed

BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs.

NUP98 NUP214

8.45e-043148223086144
Pubmed

GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.

CDSN JMJD1C

1.14e-033648223263863
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

EYA1 JMJD1C CIC

1.23e-0315248338360978
Pubmed

Loss of Rearranged L-Myc Fusion (RLF) results in defects in heart development in the mouse.

RLF JAG1

1.27e-033848227930960
InteractionDPPA3 interactions

NUP98 NUP214 NUP58 MCM3AP

1.64e-0567464int:DPPA3
InteractionSLC9A8 interactions

ZNF300 ZNF397 GALNT8

2.47e-0525463int:SLC9A8
InteractionSEH1L interactions

NUP98 MIOS SEMG1 NUP214 BECN1

2.94e-05158465int:SEH1L
InteractionNUP35 interactions

NUP98 NUP50 NUP214 NUP58 JMJD1C CIC MCM3AP

4.58e-05424467int:NUP35
InteractionNUP58 interactions

NUP98 NUP214 NUP58 UBQLN2

5.73e-0592464int:NUP58
InteractionNUP43 interactions

NUP98 RLF MUC19 NUP50 NUP214 CSMD3 JMJD1C MCM3AP

7.54e-05625468int:NUP43
Cytoband22q11.2

IGLV2-23 IGLV2-14 IGLV5-45 IGLV5-39

7.90e-0612048422q11.2
GeneFamilyNucleoporins

NUP98 NUP50 NUP214 NUP58

4.57e-07323641051
GeneFamilyImmunoglobulin lambda locus at 22q11.2

IGLV2-23 IGLV2-14 IGLV5-45 IGLV5-39

2.86e-0589364353
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GREB1L EYA1 NFAT5 JAG1

2.32e-051584741cefb82b9bf79c687a119be568cfc15b14c6e040
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 MYOCD AASS UNC80

2.44e-05160474c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 MYOCD AASS UNC80

2.44e-0516047425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellPlasma_cells|World / lung cells shred on cell class, cell subclass, sample id

IGKV1-16 IGLV2-14 IGLV5-45 PIF1

3.31e-0517347452a387e2a4694af61a9223a4c2ecf4e6f762c064
ToppCellCOPD-Lymphoid-B_Plasma|World / Disease state, Lineage and Cell class

IGKV1-16 IGLV2-23 IGLV2-14 IGLV5-45

3.46e-05175474d73ee324479172501481b54967a0f3bd870fcf3a
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

NUP98 MAN2A1 NFAT5 NLGN4Y

3.54e-051764743de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IGKV1-16 IGLV2-23 IGLV2-14 PIF1

3.62e-05177474c2b0fb5921eea24d248d6e6ccb57c29b0832602c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IGKV1-16 IGLV2-23 IGLV2-14 PIF1

3.62e-05177474111fb0707ff37ca631d85bb5a09e067ffe568eb8
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

NUP98 MAN2A1 NFAT5 NLGN4Y

3.62e-0517747482fdd6185b368f54f03de389427cbe3071d21a99
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GREB1L EYA1 NFAT5 JAG1

3.70e-05178474c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-16 IGLV2-23 IGLV2-14 IGLV5-45

3.86e-05180474cea079bc02e08c46600eed05ab9924ec90e1e3d3
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-16 IGLV2-23 IGLV2-14 IGLV5-45

3.95e-05181474e47664a264a2c37390d1668ce04eef2e0172f4cb
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-16 IGLV2-23 IGLV2-14 IGLV5-45

4.21e-0518447415f2c10101ccc8ed059520fc082ee42593dff269
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-16 IGLV2-23 IGLV2-14 IGLV5-45

4.21e-05184474a90a58d9e319afa1cd572e4c2f516fadc42f56e5
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IGKV1-16 IGLV2-23 IGLV2-14 IGLV5-45

4.30e-051854740fff2608f507e019ebb69c27e58fd5be3b049bef
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IGKV1-16 IGLV2-23 IGLV2-14 IGLV5-45

4.30e-0518547479edc1eeb7b5b9123961ac3ecf398ee68d9dddb9
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-B_cells-Immature_B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGKV1-16 IGLV2-23 IGLV2-14 IGLV5-45

4.87e-051914748c35fccc4617694eae1e55b1107841ffe7f1bac8
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

NUP98 RLF NUP58 JMJD1C

4.87e-051914741ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NUP98 PTPRM NFAT5 JMJD1C

5.07e-05193474779276e775cb2492e8dd36436295a536084a6415
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells-IgG_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGKV1-16 IGLV2-23 IGLV2-14 IGLV5-45

5.17e-05194474f083777353e76a2d9c39f8b6cb1a689b68b81c56
ToppCellBiopsy_IPF-Immune-Plasma_cells|Biopsy_IPF / Sample group, Lineage and Cell type

IGKV1-16 IGLV2-23 IGLV2-14 IGLV5-45

5.38e-05196474a1b6a8000b86efcb07843998aa3a49bb1f54bcda
ToppCellNeuronal-Excitatory-eD(FEZF2)|Neuronal / cells hierarchy compared to all cells using T-Statistic

ZNF704 MYOCD DLC1 AASS

5.82e-052004741b485ff2435c6732be58cbc9eb2f5c273f9c4bf2
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF300 IL31RA FBXO47

3.56e-041314731823cab28fab40486247ca92104267b1e370bdc1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GREB1L CDSN MYT1

4.06e-0413747348c21e6938a46e3cd74ac10b8ace0a4751741af7
ToppCellmetastatic_Lymph_Node-B_lymphocytes-Plasma_cells|metastatic_Lymph_Node / Location, Cell class and cell subclass

IGKV1-16 IGLV2-23 IGLV2-14

4.51e-041424735ba3a33c2ee20be8baaed97536ca6e9d1de6752f
ToppCellmild_COVID-19_(asymptomatic)-Treg|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

GREB1L SLC20A2 POLE2

4.79e-041454732d0903009e918500facfd017ff31f2cec1e76131
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSMD3 UNC80 MYT1

4.79e-0414547396712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellmild_COVID-19_(asymptomatic)-Treg|World / disease group, cell group and cell class (v2)

GREB1L ZNF300 SLC20A2

4.79e-04145473a3b0e1d0ce0caa8b281a146439d6455db64cc3e5
ToppCell3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-MAIT|GI_small-bowel / Manually curated celltypes from each tissue

NLGN4Y GALNT8 POLE2

4.99e-041474734ba9a86ab7033688a9a2a2dc84c001a49af835b4
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ZNF397 ACSF2 SLC20A2

5.60e-0415347391e9d70a5d3f6fd68c284ed0cc113f03d7d1e10b
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ZNF397 ACSF2 SLC20A2

5.60e-04153473f17f62646633cf95c810dcd5328978058741b276
ToppCellLPS-IL1RA+antiTNF-Unknown-Endothelial-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GREB1L MYOCD NLGN4Y

5.71e-0415447316fdafb5c64d2db321554f87129a962d113f1668
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DLC1 AASS POLE2

5.71e-04154473b6e982e341c6cfb6ff80a318078fcb10c36d182f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DLC1 AASS POLE2

5.71e-04154473d76fd51a4587decbfe1dde1c8a9b880c5fa18e4a
ToppCellnormal_Lung-B_lymphocytes-MALT_B_cells|normal_Lung / Location, Cell class and cell subclass

IGKV1-16 IGLV2-14 IGLV5-45

6.27e-04159473fbd0131b66f4267f7b0d6c3ad874ad097b859074
ToppCelltumor_Lymph_Node_/_Brain-B_lymphocytes-MALT_B_cells|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

IGKV1-16 IGLV2-14 IGLV5-45

6.27e-04159473204e5a675f4684c9570c24c8d34bbf632fd8164a
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-3|TCGA-Skin / Sample_Type by Project: Shred V9

ZNF704 EYA1 DLC1

6.27e-04159473fb222c42f66901852b01cec073ec0732245ee973
ToppCellMild-Lymphoid-Plasma-|Mild / Condition, Lineage, Cell class and cell subclass

MCF2 IGLV2-23 IGLV2-14

6.38e-04160473aa79848913910c01249d6cacf4ed53ec0e4f5c3d
ToppCellMild-Lymphoid-Plasma|Mild / Condition, Lineage, Cell class and cell subclass

MCF2 IGLV2-23 IGLV2-14

6.38e-041604737fdb849f5caf5a127a2582326215e11f8eb4fa0e
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma|TCGA-Brain / Sample_Type by Project: Shred V9

MCF2 CSMD3 UNC80

6.50e-041614735f6b2d7f80a8ee16651e304481d2da3fae313824
ToppCellBL-critical-LOC-Myeloid-Basophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ZNF704 DLC1 AASS

6.61e-0416247325ec9df914445b4daae4fd28fd0e60b64797c46d
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CSMD3 UNC80 MYT1

6.61e-04162473bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellTCGA-Adrenal-Primary_Tumor-Adrenocortical_carcinoma-Usual_Type-6|TCGA-Adrenal / Sample_Type by Project: Shred V9

SEMG1 CDSN ACSF2

6.61e-041624730e8fb83acb8ea9905cc3ca985feb8a00931549ff
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MCF2 CDSN AASS

6.85e-04164473b6df1e67a5ce5f2d86f4e1420f4ee931f760bf4d
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF704 ZNF397 CIC

6.85e-04164473b895674ed2df87db8fbfb30b7e31620945588491
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MCF2 MYOCD PIF1

6.98e-041654739de841c1c95967c562720feba930246debc626fd
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MCF2 MYOCD PIF1

6.98e-04165473a612a7d3a5415ecacc3df8fbff0ce498f982aad0
ToppCellLV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

MYOCD DLC1 JAG1

6.98e-04165473f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

POMT2 PTPRM JAG1

6.98e-0416547362457b7b74c6eae42d91d65e7dc6df6bf8e061f7
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MCF2 MYOCD PIF1

6.98e-04165473cdc94a640ec01c6892521bcd6f0ee0a66ff23866
ToppCell367C-Lymphocytic-Plasma_cell-|367C / Donor, Lineage, Cell class and subclass (all cells)

IGLV2-23 IGLV2-14 IGLV5-45

7.22e-04167473f2185eb72f0137136f6d71af2a70168fded6c940
ToppCell367C-Lymphocytic-Plasma_cell|367C / Donor, Lineage, Cell class and subclass (all cells)

IGLV2-23 IGLV2-14 IGLV5-45

7.22e-041674735e768cf24699893e05d1bcb1c92dba2336943a64
ToppCellBAL-Mild-Lymphocyte-B|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-16 IGLV2-23 IGLV2-14

7.48e-04169473307571e57c3bfdf15f0fe1a8b36585e8e4f8a207
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CDSN PTPRM JAG1

7.48e-04169473c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLDN18 DLC1 GALNT8

7.48e-04169473cd16e8462ee09877be962fbd9a3badcb825820b0
ToppCellmetastatic_Brain-B_lymphocytes-Plasma_cells|metastatic_Brain / Location, Cell class and cell subclass

IGKV1-16 IGLV2-23 IGLV2-14

7.61e-0417047353634da9e9c72f6400639954c286c6e38ea5a188
ToppCell368C-Myeloid-Monocyte-CD16+_Monocyte|Monocyte / Donor, Lineage, Cell class and subclass (all cells)

CLDN18 PTPRM MCM3AP

7.61e-041704734a19c7e3bb0f9c2601a10debe7000066789b4150
ToppCell10x5'-Lung-Lymphocytic_B-Memory_B_cells|Lung / Manually curated celltypes from each tissue

IGKV1-16 IGLV2-14 MYT1

7.87e-041724732cb2dc7cfd6db5a98a393b1a84c23abf3d692a53
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

NUP98 POMT2 POLE2

8.00e-04173473b9dee61973559e8c2fef3f2dafd43475b386befb
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-arterial_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MUC19 PTPRM JAG1

8.00e-041734733a9e9a09b3eeb37cbe56d650e112a8398879477f
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-16 IGLV2-14 IGLV5-45

8.00e-041734737e6bfe85f60834f317941b70d6e0dc3bd527d293
ToppCellCOVID-19-Heart-VSMC|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYOCD DLC1 JAG1

8.27e-041754731125f0d3a5b2388fa77a820dea0288e824d84a82
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 CSMD3 UNC80

8.27e-04175473887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCellmetastatic_Brain-B_lymphocytes-MALT_B_cells|metastatic_Brain / Location, Cell class and cell subclass

IGLV2-23 IGLV2-14 IGLV5-45

8.41e-0417647350e207403d48ce1b55a78897adb5519a2430a626
ToppCellControl-Lymphoid_P|Control / Disease group, lineage and cell class

IGKV1-16 IGLV2-23 IGLV2-14

8.41e-04176473d895a6b295cd649273ff80ad7785a3e0ae4c728a
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

NUP98 POMT2 POLE2

8.41e-04176473437cfc5e06416bb0fc76d1f9dc106f74e279e880
ToppCellControl-Lymphoid_P-Plasmablast|Control / Disease group, lineage and cell class

IGKV1-16 IGLV2-23 IGLV2-14

8.41e-041764734b4416f342b732d2cc60133838728880326257d8
ToppCell-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

IGKV1-16 IGLV2-14 PIF1

8.55e-04177473ae2d2e138946535596fa30a55207f261cafda461
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IGKV1-16 IGLV2-23 IGLV2-14

8.55e-041774734c434a7b7cc54cf4dac996bbc3f5124d9ef9a9cd
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGKV1-16 IGLV2-23 IGLV2-14

8.55e-04177473fc40918825b7e1eb6861df59dfca944778a64b98
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGKV1-16 IGLV2-23 IGLV2-14

8.55e-04177473d746122bf8d208c3aa4d156e8c12d0a0e555c6e5
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-5|TCGA-Skin / Sample_Type by Project: Shred V9

IL31RA GALNT8 MYT1

8.69e-04178473ad5cd505ca1cef8ac29b2af7e2c3e01ebc140c14
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GREB1L EYA1 PTPRM

8.69e-04178473e86ed30652c2de70f16430f04b78789b87df4af2
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGLV2-23 IGLV2-14 IGLV5-45

8.69e-04178473107dae8b00c4257697a63700e72bb434cdb8406f
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-16 IGLV2-23 IGLV2-14

8.83e-04179473837ed81f18257f444eaeadc4fac89deedd4e3061
ToppCellPCW_07-8.5-Neuronal-Neuronal_postreplicative-neuro_migrating_neuronal_(3)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

EYA1 UNC80 MYT1

8.83e-04179473df6d2cdc4e204ce1a4628dc71dfbc5e6c6309b2a
ToppCellCOVID-19-Heart-VSMC|Heart / Disease (COVID-19 only), tissue and cell type

MYOCD DLC1 JAG1

8.83e-04179473a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-16 IGLV2-23 IGLV2-14

8.83e-04179473494febe77c6d4e6a2c6f0928bbf4c84b0301f188
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-16 IGLV2-23 IGLV2-14

8.83e-04179473b6ee4f41d8fb5f047b7bdd8489dda0a89fc6d43f
ToppCell3'_v3-bone_marrow-Mast|bone_marrow / Manually curated celltypes from each tissue

ZNF704 CDSN DLC1

8.97e-04180473b37ee81b792213d6595b4ec65d04bc35d83321c7
ToppCellfacs-Lung-18m-Mesenchymal-myofibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZNF704 MYOCD SH3D21

9.12e-04181473dff264815a3569f5666d0bbc3867c0496cd78774
ToppCellfacs-Heart-RA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOCD CDSN JAG1

9.12e-04181473429df38438d5a7ff490c9ede34b69e2970c7ded2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GREB1L EYA1 NFAT5

9.12e-041814736a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCellfacs-Heart-RA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOCD CDSN JAG1

9.12e-04181473395cf5aa2d89b05328ab516b8c89401020b6d830
ToppCell3'_v3-bone_marrow-Mast-Mast_cells|bone_marrow / Manually curated celltypes from each tissue

ZNF704 CDSN DLC1

9.12e-0418147330ec4635474ee0f0ea1415ec0ba7f008d97e8c1a
ToppCellCOPD-Myeloid-Mast|World / Disease state, Lineage and Cell class

ZNF704 MAN2A1 AASS

9.26e-0418247368a1e7b804f309bfd6c23d65fad20a9a962712ae
ToppCellmetastatic_Lymph_Node-B_lymphocytes-Plasma_cells|B_lymphocytes / Location, Cell class and cell subclass

IGKV1-16 IGLV2-23 IGLV2-14

9.26e-0418247327d1688fdfc570cedd233aa7030bce7d9b604d42
ToppCell10x5'-Lung-Lymphocytic_B|Lung / Manually curated celltypes from each tissue

IGKV1-16 IGLV2-14 MYT1

9.26e-04182473310f94437d197eaaaf6e30e68063b33e94befe77
ToppCellcellseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IGLV2-23 IGLV2-14 IGLV5-45

9.41e-041834735ab4aa0304b832f98fff89b6c24ad5b7dd014c11
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYOCD DLC1 JAG1

9.41e-04183473667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP2_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

EYA1 MYT1 PIF1

9.41e-04183473e0854864d377e158a4793088d1cb6b3dbf2c805d
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-16 IGLV2-23 IGLV2-14

9.41e-04183473cf5c98f451a568308c52da5c926543dd4836c6b2
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOCD CSMD3 UNC80

9.56e-04184473ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOCD CSMD3 UNC80

9.56e-041844732cbed6462fea2622871bb7e49b0df3d984239281
ToppCellwk_15-18-Hematologic_Lymphocytic-B-CD5+_CCL22-_mature_B|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

IGLV2-23 IGLV2-14 IGLV5-45

9.56e-0418447318aa9c43b79d12c9e420dfd9822745c022be6789
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOCD CSMD3 UNC80

9.56e-041844732b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EYA1 NFAT5 JAG1

9.56e-04184473da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

GREB1L MYOCD PTPRM

9.56e-04184473ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GREB1L EYA1 PTPRM

9.71e-0418547379cff4f3c6ae8e5ea60e8eae082b9275f2679ee9
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGLV2-23 IGLV2-14 PIF1

9.71e-04185473ff598af88c7f9d7224cc4ed96b1c3463ef76b550
DiseaseAsymmetric crying face association

EYA1 JMJD1C

1.02e-0410452C0431406
Diseasepulse pressure measurement

CDSN UBQLN2 DLC1 NFAT5 SLC20A2 MYT1 PIF1 JAG1

1.09e-031392458EFO_0005763
Diseaseosteoarthritis (is_marker_for)

BECN1 JAG1

1.31e-0335452DOID:8398 (is_marker_for)
Diseasesystemic lupus erythematosus (implicated_via_orthology)

MAN2A1 BECN1

1.97e-0343452DOID:9074 (implicated_via_orthology)
DiseaseCongenital Heart Defects

EYA1 JAG1

2.07e-0344452C0018798
Diseasetestosterone measurement

ZNF704 MYOCD UBQLN2 EYA1 CSMD3 JMJD1C SLC20A2

2.98e-031275457EFO_0004908

Protein segments in the cluster

PeptideGeneStartEntry
PNGNKIGTQTSYGST

CSMD3

2766

Q7Z407
PLTFVFTGTGNVSKG

AASS

216

Q9UDR5
GNINFFGGPSNTSVK

POLE2

256

P56282
QFTSGTTGSPKGATL

ACSF2

261

Q96CM8
GSAGSFKPGTGYSQV

CDSN

101

Q15517
TGFSFSPGNSSLFGK

NUP50

291

Q9UKX7
QTKPGGLFGTSSFSQ

NUP98

56

P52948
QNKPTGFGNFGTSTS

NUP98

111

P52948
SGGLFGTTNTTSNPF

NUP98

126

P52948
KTAFGTSTTGFGTNP

NUP98

256

P52948
GSTLFGNNKLTTFGS

NUP98

361

P52948
GTNTSGNSIFGSKPA

NUP98

411

P52948
GGLLQSKFTSGAFLS

NUP98

1046

P52948
GPKSSQSNFSQGAGS

MAN2A1

86

Q16706
DKQQGSGVPSRFSGS

IGLV5-39

76

A0A0G2JS06
GGTNGTSINFKTLSF

IL31RA

501

Q8NI17
SKTGSVVQPSSGFSG

JMJD1C

1461

Q15652
GNTGFSFKSPTSVGA

MCM3AP

106

O60318
TGGSGGSYSIKTQFN

BECN1

406

Q14457
PSGVSNRFSGSKSGN

IGLV2-23

76

P01705
SGPSAKVTGNYGQSS

MUC19

2046

Q7Z5P9
QSPGQTGFLSYGTSF

EYA1

156

Q99502
ASGQFSKPFSFSPSG

NUP214

1206

P35658
QPTKTSGVPSGFNFT

NUP214

1361

P35658
GGFASSSFGEQKPTG

NUP214

1931

P35658
SSFGEQKPTGTFSSG

NUP214

1936

P35658
SQGFGFSSPNKTGGF

NUP214

1956

P35658
SNASAPGTFGSLSKG

ANKS4B

186

Q8N8V4
TPENGTTNGYKSGFT

GREB1L

261

Q9C091
SPGSSQQTSGMFLFG

NFAT5

1436

O94916
NSFSGQTGVSSFKPG

MYOCD

351

Q8IZQ8
PLHTFKTFSGGQNST

NLGN4Y

791

Q8NFZ3
VFSSKGTLQNLFTGG

GALNT8

26

Q9NY28
NLVTSGTPFFSSKQG

MCF2

441

P10911
LGSGFQPISTFGNFK

FBXO47

31

Q5MNV8
LQSGVPSKFSGSGSG

IGKV1-16

76

P04430
SVKSPISNGTFGFDG

SLC20A2

321

Q08357
KPGGFKASTGFGSNT

CLDN18

221

P56856
ASTFGFGTTNKPSGS

NUP58

526

Q9BVL2
FGTTNKPSGSLSAGF

NUP58

531

Q9BVL2
STAKGFGPPATNQFT

PTPRM

566

P28827
SGSTPVIGGNTFNLK

JAG1

96

P78504
PSGVSNRFSGSKSGN

IGLV2-14

76

P01704
GQSIFFTGSAGTGKS

PIF1

221

Q9H611
SQKLTSRDSGPNGGF

SH3D21

181

A4FU49
SKSGPGDGFFSSAFQ

POMT2

306

Q9UKY4
DKQQGSGVPSRFSGS

IGLV5-45

76

A0A087WSX0
QGNSPSGKGISSQYS

SEMG1

146

P04279
VKNSQSFFSGLFGGS

NAPA

21

P54920
GTFPKALTNGSFSPS

DLC1

816

Q96QB1
TFKAQESGQGSTAGP

CIC

556

Q96RK0
TNGGQKPSSSDTFFR

UHRF1BP1L

781

A0JNW5
PSEGAFQFKGVSGSS

UNC80

711

Q8N2C7
RGFSQYGVSGSPTKS

MIOS

756

Q9NXC5
FSGSLQGYPSSGAKS

RLF

1081

Q13129
IPGSAKFTPNGSSFS

ZNF704

316

Q6ZNC4
GEKLRSPSQGGSFSQ

ZNF397

231

Q8NF99
QFGGNPFASVGSSSS

UBQLN2

286

Q9UHD9
KPDQSFGGGKSSSQS

ZNF300

211

Q96RE9
FGGGKSSSQSEPNSN

ZNF300

216

Q96RE9
FGSNPIGSATASSKG

MYT1

141

Q01538