Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentF-actin capping protein complex

CAPZA1 CAPZA2

1.54e-049442GO:0008290
GeneOntologyCellularComponentaxon

NAV1 ROBO2 RIN3 CAD SHANK2 KIF1A DSCAML1 SCN3A

4.78e-04891448GO:0030424
GeneOntologyCellularComponentlateral element

BRCA2 STAG3

7.24e-0419442GO:0000800
HumanPhenoHypogeusia

KIF1A WNK1

7.59e-056122HP:0000224
HumanPhenoAbnormality of taste sensation

KIF1A WNK1

1.06e-047122HP:0000223
HumanPhenoPainless fractures due to injury

KIF1A WNK1

1.41e-048122HP:0002661
HumanPhenoFoot acroosteolysis

KIF1A WNK1

1.41e-048122HP:0001842
HumanPhenoOsteolytic defects of the phalanges of the toes

KIF1A WNK1

1.41e-048122HP:0010177
HumanPhenoAcral ulceration

KIF1A WNK1

1.81e-049122HP:0006121
HumanPhenoDigital ulcer

KIF1A WNK1

1.81e-049122HP:0031917
HumanPhenoDecreased corneal reflex

KIF1A WNK1

2.27e-0410122HP:0008000
HumanPhenoAbnormal corneal reflex

KIF1A WNK1

3.31e-0412122HP:0034251
HumanPhenoOsteolysis involving bones of the feet

KIF1A WNK1

3.31e-0412122HP:0009134
HumanPhenoOsteolysis involving bones of the lower limbs

KIF1A WNK1

3.91e-0413122HP:0009139
DomainF_ACTIN_CAPPING_A_1

CAPZA1 CAPZA2

1.62e-053442PS00748
DomainF_ACTIN_CAPPING_A_2

CAPZA1 CAPZA2

1.62e-053442PS00749
DomainF-actin_cap_A

CAPZA1 CAPZA2

1.62e-053442PF01267
DomainCapZ_alpha

CAPZA1 CAPZA2

1.62e-053442IPR002189
DomainF-actin_cap_asu_CS

CAPZA1 CAPZA2

1.62e-053442IPR017865
DomainNeurotransmitter_ion_chnl_CS

GABRP CHRNB1

5.04e-0345442IPR018000
DomainNeur_chan_memb

GABRP CHRNB1

5.26e-0346442PF02932
DomainNeur_chan_LBD

GABRP CHRNB1

5.48e-0347442PF02931
DomainNEUROTR_ION_CHANNEL

GABRP CHRNB1

5.48e-0347442PS00236
DomainNeurotrans-gated_channel_TM

GABRP CHRNB1

5.48e-0347442IPR006029
Domain-

GABRP CHRNB1

5.48e-03474422.70.170.10
DomainNeur_channel

GABRP CHRNB1

5.48e-0347442IPR006201
DomainNeur_chan_lig-bd

GABRP CHRNB1

5.48e-0347442IPR006202
Domainfn3

ROBO2 IGSF22 DSCAML1

6.54e-03162443PF00041
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

NAV1 CAD BRCA2 WNK1 KRT19 USP28 ZGRF1 CAPZA1 CAPZA2

5.47e-0858845938580884
Pubmed

Diagnostic utility of LDH, CA125 and CYFRA21-1 in tuberculosis pleural effusion.

MUC16 KRT19

1.64e-06245233495032
Pubmed

Vertebrates have conserved capping protein alpha isoforms with specific expression patterns.

CAPZA1 CAPZA2

4.91e-0634529331217
Pubmed

Clinical Evaluation of Tumor Markers for Diagnosis in Patients with Non-small Cell Lung Cancer in China.

MUC16 KRT19

4.91e-06345226163610
Pubmed

Solution NMR structure of S100B bound to the high-affinity target peptide TRTK-12.

CAPZA1 CAPZA2

4.91e-06345212470955
Pubmed

Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors.

CAPZA1 CAPZA2

4.91e-06345234796874
Pubmed

Rewarding effects of opiates are absent in mice lacking the receptor for substance P.

ROBO2 TACR1

4.91e-06345210821273
Pubmed

Sequence analysis and chromosomal localization of human Cap Z. Conserved residues within the actin-binding domain may link Cap Z to gelsolin/severin and profilin protein families.

CAPZA1 CAPZA2

9.81e-0644527665558
Pubmed

Deregulation of CRAD-controlled cytoskeleton initiates mucinous colorectal cancer via β-catenin.

CAPZA1 CAPZA2

9.81e-06445230361697
Pubmed

Hereditary Sensory and Autonomic Neuropathy Type II

KIF1A WNK1

9.81e-06445221089229
Pubmed

Mammalian CARMIL inhibits actin filament capping by capping protein.

CAPZA1 CAPZA2

9.81e-06445216054028
Pubmed

Identifying the cellular origin of squamous skin tumors.

BRCA2 KRT19

2.45e-05645221502497
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

PRICKLE2 REV3L CCDC73 KIF1A KRT19 DSCAML1 SCN3A

4.17e-0573645729676528
Pubmed

The phosphorylation of CapZ-interacting protein (CapZIP) by stress-activated protein kinases triggers its dissociation from CapZ.

CAPZA1 CAPZA2

8.94e-051145215850461
Pubmed

Mapping of the mouse actin capping protein alpha subunit genes and pseudogenes.

CAPZA1 CAPZA2

8.94e-05114529119363
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

NAV1 DENND4A WNK1 KRT19 PCDH7 BACH1 RUSC2

1.11e-0486145736931259
Pubmed

Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice.

CAPZA1 CAPZA2

3.06e-042045218723693
Pubmed

The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85.

CAPZA1 CAPZA2

4.44e-042445221822214
Pubmed

Substrate specificities and identification of putative substrates of ATM kinase family members.

PPP2R3A BRCA2

4.82e-042545210608806
Pubmed

A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers.

CAD BRCA2 KRT19

5.76e-0412545321654808
Pubmed

Genetic variation in immune regulation and DNA repair pathways and stomach cancer in China.

REV3L BRCA2

6.06e-042845219661089
Pubmed

Identification of 14-3-3epsilon substrates from embryonic murine brain.

NAV1 CAPZA1 CAPZA2

6.75e-0413245316944949
Pubmed

Multiple roles of FOXJ3 in spermatogenesis: A lesson from Foxj3 conditional knockout mouse models.

BRCA2 STAG3

7.92e-043245227739607
Pubmed

Robo signalling controls pancreatic progenitor identity by regulating Tead transcription factors.

ROBO2 KRT19

8.94e-043445230504829
Pubmed

Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.

NAV1 RUSC2 CAPZA1 CAPZA2

1.22e-0336145430344098
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

DNAAF9 REV3L KIF1A DSCAML1 USP28 BACH1 CAPZA2

1.23e-03128545735914814
Cytoband11q23

DSCAML1 USP28

5.79e-043645211q23
GeneFamilyFibronectin type III domain containing

ROBO2 IGSF22 DSCAML1

2.32e-03160303555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

ROBO2 IGSF22 DSCAML1

2.36e-03161303593
GeneFamilyUbiquitin specific peptidases

USP38 USP28

3.88e-0356302366
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

PRICKLE2 NAV1 ROBO2 PPP2R3A CCPG1 REV3L SHANK2 KIF1A PCDH7 DSCAML1 SCN3A RUSC2

1.81e-0711064412M39071
CoexpressionGSE7218_IGM_VS_IGG_SIGNAL_THGOUGH_ANTIGEN_BCELL_UP

NAV1 CAD REV3L MED16 RUSC2

1.52e-05187445M6807
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

MUC16 GABRP TACR1 SHANK2 KRT19 PCDH7

2.88e-081824563f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPP2R3A HMGCS2 WNK1 KRT19 PCDH7 SCN3A

3.28e-0818645608632045d499e61dd96ff29a5a9a208afe58dc58
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MUC16 GABRP TACR1 KRT19 PCDH7

8.56e-07173455464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP13A4 TACR1 SHANK2 KRT19 DSCAML1

9.58e-071774559af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCellControl-Epithelial_alveolar-AT_1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP13A4 TACR1 SHANK2 KRT19 DSCAML1

9.85e-07178455aa7d43c655df493f1330a5001efaa484e4a19f69
ToppCellControl-Epithelial_alveolar-AT_1-AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP13A4 TACR1 SHANK2 KRT19 DSCAML1

9.85e-071784551817bc520f3d23da8c0fa09bba50ae703a820cb1
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP13A4 TACR1 SHANK2 KRT19 DSCAML1

1.01e-0617945504ce3673e46606f63d9c87bcba3a64c96817d812
ToppCellControl-Epithelial_cells-Airway_mucous|Control / group, cell type (main and fine annotations)

MUC16 GABRP KRT19 SCN3A MGAM2

1.13e-0618345515d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPP2R3A WNK1 KRT19 PCDH7 SCN3A

1.22e-06186455d65fa6d8e8a195ea10cfde1499d096d6acf7a634
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 GABRP CCPG1 HMGCS2 KRT19

1.47e-06193455605fc2a25ed6846fb283b2918cfed98df6039d6b
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 TACR1 SHANK2 KRT19 PCDH7

1.66e-06198455fab3135f03cf23a9f04f0eed543a9dc181f39f5f
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 GABRP CCPG1 HMGCS2 KRT19

1.70e-061994551e693d7bb481bf03a943b460a69787229625d7b1
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

MUC16 CFAP54 SHANK2 KRT19

1.63e-051514548216462e723fec2797387929dde095370947e10a
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TACR1 SHANK2 KRT19 DSCAML1

1.90e-051574549665a1375cfd8e9b8781c852686591226c0e0d9a
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 GABRP KRT19 ZGRF1

1.90e-05157454c43f2e1ea53b375a7432f17f87cfef3b2261003d
ToppCellwk_20-22-Epithelial-Proximal_epithelial-SMG_basal_1|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

GABRP SHANK2 KRT19 MGAM2

1.95e-05158454adad97e6cf479d42791c5ba9cbc5f15f469322bf
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TACR1 SHANK2 KRT19 DSCAML1

2.10e-051614541e17a993126e1f2a25ee7dfbb95a74ccb2a26791
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MUC16 GABRP SHANK2 PCDH7

2.10e-051614542d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ATP13A4 CFAP54 SHANK2 KRT19

2.31e-0516545482530f96aaefe28a13bad0474bbad043f127a86c
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ATP13A4 CFAP54 SHANK2 KRT19

2.31e-051654540c714e852f912b5749de4cb0895406673979b2e6
ToppCell15-Airway-Epithelial-Club-like_secretory|Airway / Age, Tissue, Lineage and Cell class

MUC16 GABRP ATP13A4 KRT19

2.60e-051704541418031cc4b4a87a48621eb53a3c819cd713ddd0
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_3|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

MUC16 GABRP ATP13A4 KRT19

2.84e-051744549e5fae9ecc7c0111fc8a252e72b89dc89c0d3a7c
ToppCell(00)_Basal-(2)_48hpi|(00)_Basal / shred by cell type and Timepoint

MUC16 GABRP KRT19 CAPZA1

2.97e-051764540f6770296d7fa453ffbf6ca6d5fdebc888f6eb60
ToppCellpdx-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ROBO2 DNAAF9 SHANK2 DSCAML1

2.97e-051764541e21f80cf0e695ffdd63e4a72cf1e3fa41b60341
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Proximal_secretory_3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MUC16 GABRP ATP13A4 KRT19

2.97e-051764548d9d0fb46c418b2067be58aec822e8c2b1561461
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

PPP2R3A CFAP54 SHANK2 DSCAML1

3.11e-05178454544379f5a6145429762258d426b876bb36c112f5
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PRICKLE2 ATP13A4 HMGCS2 SHANK2

3.11e-05178454f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCellAdult-Epithelial-lung_goblet_cell|Adult / Lineage, Cell type, age group and donor

MUC16 TACR1 KRT19 PCDH7

3.18e-051794541fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCellnucseq-Epithelial-Epithelial_Glandular|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 GABRP KRT19 MGAM2

3.18e-05179454859cd8ee414ad6207c046ada2e655e49322dd01c
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 GABRP KRT19 MGAM2

3.25e-051804543dc80bc636bf0e6ffc9762853132a9fe59fd1f66
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 GABRP KRT19 MGAM2

3.25e-05180454668a2d8e1d5a390309d5eb62c836f5903144bea9
ToppCellControl-Epithelial_alveolar-AT_1-AT1-AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP13A4 TACR1 SHANK2 KRT19

3.39e-05182454a95956ce4adccb34cc0c47ebfa1878ce4617904e
ToppCellCOVID-19-Epithelial_cells-ECM-high_epithelial|COVID-19 / group, cell type (main and fine annotations)

ROBO2 ATP13A4 SHANK2 KRT19

3.46e-05183454dc1d380bf7564f290256cb7108063d1bd2da732b
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP13A4 TACR1 SHANK2 KRT19

3.46e-05183454274483009b309289e4cb84beedf6806430db6ff6
ToppCellEpithelial-lung_goblet_cell|World / Lineage, Cell type, age group and donor

MUC16 TACR1 SHANK2 KRT19

3.46e-05183454940cbe298e9c53b5622af09264586ed823d3141f
ToppCellCOPD-Epithelial-Basal|COPD / Disease state, Lineage and Cell class

ATP13A4 SHANK2 KRT19 PCDH7

3.46e-051834540f760e393edc91009bf6c7e02eeac039a1dfb4ed
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

WNK1 KRT19 PCDH7 SCN3A

3.54e-051844549690d4290e70f9bda889754ffb30b0af1f7cb94b
ToppCellControl-Epithelial_cells-Airway_goblet|Control / group, cell type (main and fine annotations)

MUC16 GABRP KRT19 MGAM2

3.54e-05184454d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCellLPS_only-Epithelial_alveolar-AT_1-AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP13A4 SHANK2 KIF1A KRT19

3.61e-051854540c247a3f394c42e2a6f67fee3d9cf33096fecd13
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

PRICKLE2 ATP13A4 HMGCS2 SHANK2

3.61e-05185454673f0c688ae6984bc8027df2da335787924f4137
ToppCellControl-Epithelial_alveolar|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP13A4 TACR1 SHANK2 KRT19

3.61e-051854543937e026add96a396122139daf8011cfbc60e75c
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

PRICKLE2 ATP13A4 HMGCS2 SHANK2

3.61e-0518545498b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPP2R3A DENND4A CFAP54 DSCAML1

3.69e-05186454f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

WNK1 KRT19 PCDH7 SCN3A

3.69e-05186454b3358e0fa6d845c81e94d56c8575f016621d28ff
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP13A4 SHANK2 KRT19 DSCAML1

3.69e-051864543aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPP2R3A DENND4A CFAP54 DSCAML1

3.77e-05187454c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMGCS2 SHANK2 KRT19 CHRNB1

3.77e-051874549aa411ae9b5a923378a5daebb8bb2fc2613f2510
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Proximal_secretory_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

MUC16 GABRP ATP13A4 KRT19

3.85e-0518845407705bed928683470a52c8ccfa40ffb9a0971318
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ATP13A4 CFAP54 SHANK2 DSCAML1

3.85e-0518845463a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellCOVID-19-kidney-CD-PC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PPP2R3A HMGCS2 SHANK2 KRT19

3.85e-051884548f9996c3f3b27efaaae8960a66af77412de9c7ef
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ROBO2 SHANK2 PCDHGA2 SCN3A

3.85e-05188454e239bcdbd210a398a5850cb6fbf171d402f45a4f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

WNK1 KRT19 PCDH7 SCN3A

3.85e-051884544154f4787483c7e076e87a187733a9f666742c3d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HMGCS2 KRT19 PCDH7 SCN3A

3.93e-051894543a295c215b5c18e7c673f92b7af5be523421682c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO2 HMGCS2 KRT19 PCDH7

3.93e-05189454fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HMGCS2 KRT19 PCDH7 SCN3A

3.93e-05189454532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

WNK1 KRT19 PCDH7 SCN3A

3.93e-0518945490aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCellCOVID-19-Epithelial_cells-Airway_goblet|COVID-19 / group, cell type (main and fine annotations)

MUC16 TACR1 SHANK2 KRT19

4.01e-0519045451ca9ef4df3220487152fcf684147730637c7cc1
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ATP13A4 CFAP54 SHANK2 KRT19

4.09e-0519145460ff989fe99d243a3d52955223680cdd1f1917a4
ToppCellNS-critical-d_16-33-Epithelial-Secretory-diff|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MUC16 GABRP CCPG1 KRT19

4.18e-0519245402b11233b4da2d85b96498b3c6e22e3a31b3d049
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO2 KRT19 PCDH7 SCN3A

4.18e-051924540bb06738e1c3ec0c044a7ee61f6cf1d4781fb53c
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ATP13A4 CFAP54 SHANK2 KRT19

4.18e-05192454b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCellCOPD-Epithelial|COPD / Disease state, Lineage and Cell class

PRICKLE2 ATP13A4 SHANK2 KRT19

4.18e-051924540644fad5df18f0021f6f49cca996d8cf47f972ff
ToppCellCOVID-19-kidney-CNT|kidney / Disease (COVID-19 only), tissue and cell type

PPP2R3A KRT19 PCDH7 SCN3A

4.18e-05192454d32ae226d95b4b6adb99d14b602be09b661d4cd9
ToppCellfacs-Pancreas-Exocrine-3m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMGCS2 SHANK2 KRT19 CHRNB1

4.26e-05193454c3161a14a40323a58aa202c8a1d6ea0e9c2b9814
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HMGCS2 WNK1 KRT19 PCDH7

4.26e-0519345446d5d1f8150ebbc7f1941b96ab184491e5c1210b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO2 HMGCS2 KRT19 SCN3A

4.35e-05194454be869e186386d03ebb670971dd24fa656b4b0edf
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ATP13A4 CFAP54 SHANK2 KRT19

4.35e-051944546b286992d4bb56013c0ea5a7601d3476d806175a
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ATP13A4 CFAP54 SHANK2 KRT19

4.35e-05194454f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO2 HMGCS2 KRT19 SCN3A

4.35e-051944544d6c9b016e3a0641954a8ea10c97d1cd76fadd9f
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

PRICKLE2 CFAP54 SHANK2 KRT19

4.44e-05195454fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PPP2R3A DNAAF9 SHANK2 DSCAML1

4.44e-051954546477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellControl-Multiplet|Control / Disease state, Lineage and Cell class

PRICKLE2 ATP13A4 SHANK2 KRT19

4.44e-05195454618900c80bea09d46dad3f741bd1bff8bf0a64ee
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

PRICKLE2 CFAP54 SHANK2 KRT19

4.44e-05195454eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellControl-Multiplet-Multiplet|Control / Disease state, Lineage and Cell class

PRICKLE2 ATP13A4 SHANK2 KRT19

4.44e-0519545406ac685855e14e4dd2cbe6d0e73f894f2eeff91f
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

PRICKLE2 CFAP54 SHANK2 KRT19

4.44e-0519545421dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCellCOVID-19-Epithelial-Club,_Basal_cells|COVID-19 / Condition, Lineage and Cell class

MUC16 GABRP TACR1 KRT19

4.53e-05196454dd32046067d93b9484cfbf1d7826a436a3d9f0e9
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

PRICKLE2 CFAP54 SHANK2 KRT19

4.53e-051964546d02d494196e3f857d53eea46d9419690d43beca
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 GABRP KRT19 PCDH7

4.53e-05196454b07db4a53ab9be9aad6fae5e45f9547db829d096
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPP2R3A SHANK2 PCDH7 SCN3A

4.53e-05196454c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

PRICKLE2 CFAP54 SHANK2 KRT19

4.53e-05196454af4cdc61830685a888a1209826c23bcf54a43084
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A WNK1 CAPZA1 CAPZA2

4.53e-05196454151f1a29a91f8b234e9b6ed062666357a2f69128
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

PRICKLE2 CFAP54 SHANK2 KRT19

4.53e-0519645487d9881cfec461a5d89b688a83749b618c519485
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ATP13A4 SHANK2 KRT19 DSCAML1

4.71e-05198454b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TPRX1 KIF1A DSCAML1 SCN3A

4.71e-051984548f25e8dff42bad8e779ca618bdb1cb1610667962
ToppCellwk_08-11-Epithelial-Proximal_epithelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

MUC16 KIF1A KRT19 SCN3A

4.71e-051984549895f1d65d18d939f3974a914ee41c6d5575e765
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TPRX1 KIF1A DSCAML1 SCN3A

4.71e-05198454e3e0aa3ef20b2370f5b133048510677aaa562dfa
ToppCellNS-moderate-d_07-13-Epithelial-Secretory-diff|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MUC16 GABRP CCPG1 KRT19

4.71e-05198454361f3062f73a0add16dd6fbe927698416515879f
ToppCellBL-critical-LOC-Epithelial-Secretory_LYPD2|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MUC16 GABRP HMGCS2 KRT19

4.71e-05198454484d16aaa601a1e11b871b0475dd01a2de1a29ce
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ATP13A4 SHANK2 KRT19 DSCAML1

4.80e-05199454a270630626df614f8605abddb7dee7c4d74f6149
ToppCellTracheal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Duct|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 GABRP SHANK2 KRT19

4.80e-05199454ef1a0c278c23614fd6a3218a9733abe6ecd6f686
ToppCellTracheal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Mucous|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 HMGCS2 SHANK2 KRT19

4.80e-05199454f37114cf849837fdb8ed9a767de773e8681b7df3
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ATP13A4 SHANK2 KRT19 DSCAML1

4.80e-05199454d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal-Suprabasal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 GABRP KRT19 PCDH7

4.80e-05199454f5c3561744e2a0e7716657cb521acb1d8f054b41
ToppCellmoderate-Epithelial-Secretory-diff|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MUC16 GABRP CCPG1 KRT19

4.89e-052004546f29ef9dcf126c5c19386f6aa9a20c38a2c8ccc8
ToppCellParenchyma_COVID-19-Epithelial-TX-Club|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

MUC16 GABRP TACR1 KRT19

4.89e-0520045485f946dd3831acf3488c87efba96689cc2667c3a
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 TACR1 KRT19 PCDH7

4.89e-05200454b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCellNasal_Brush-Epithelial|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

MUC16 GABRP CCPG1 KRT19

4.89e-052004547911073119ee47a37b68b73fc54f063e902a5067
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ATP13A4 SHANK2 KRT19 DSCAML1

4.89e-05200454ddfb1f006365bf16203ee49f20200f68220cc288
ToppCellNS-moderate-d_16-33-Epithelial-Secretory-diff|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MUC16 GABRP CCPG1 KRT19

4.89e-052004548f179b5768fd504af6dd6f6749a0bed7b689e77f
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Club-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MUC16 GABRP TACR1 KRT19

4.89e-052004548a44a4f7ea9358f2194a490e79601c98ff7fdcb0
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

HMGCS2 WNK1 KRT19

1.57e-0450233GAVISH_3CA_METAPROGRAM_EPITHELIAL_METABOLISM_KIDNEY_2
DiseaseNeuropathy, hereditary sensory and autonomic, type 2A

KIF1A WNK1

1.30e-054442cv:C2752089
DiseaseNeuropathy, Hereditary Sensory And Autonomic, Type IIA

KIF1A WNK1

1.30e-054442C2752089
DiseaseNEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE IIA

KIF1A WNK1

1.30e-054442201300
DiseaseHereditary sensory and autonomic neuropathy type 2

KIF1A WNK1

1.30e-054442cv:C5574675
Diseasehereditary sensory neuropathy (is_implicated_in)

KIF1A WNK1

1.30e-054442DOID:0050548 (is_implicated_in)
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

GABRP CAPZA1 CAPZA2

5.43e-0549443DOID:0060037 (implicated_via_orthology)
DiseaseHereditary Motor and Sensory-Neuropathy Type II

KIF1A WNK1

1.68e-0413442C0270914
Diseaseseborrheic dermatitis

PRICKLE2 TACR1

4.06e-0420442EFO_1000764
DiseaseRS-6-hydroxywarfarin measurement

ATP13A4 SHANK2 PCDH7

1.61e-03155443EFO_0803328
Diseasesystemic juvenile idiopathic arthritis

PRICKLE2 RIN3

1.64e-0340442EFO_1001999

Protein segments in the cluster

PeptideGeneStartEntry
MSLSENSVFAYESSV

BACH1

1

O14867
MSKTQTVYDSDSQSG

CFAP54

1581

Q96N23
SSSLTMSEYFQNTSL

C2orf78

26

A6NCI8
KMESNSTFTSFENTT

ATP13A4

1026

Q4VNC1
TAISENYQTMSDTTF

CAPZA1

241

P52907
TMVFSSYSYDSSEVS

CHRNB1

166

P11230
FTMYTTSSKDQSSDR

DENND4A

1341

Q7Z401
EFYMTSATSSVSEDS

PCDHGA2

346

Q9Y5H1
DTAVTNMEATSSEYS

MUC16

4246

Q8WXI7
MTSYSYRQSSATSSF

KRT19

1

P08727
VDTTSNSFSIMTTSF

MGAM2

2191

Q2M2H8
NSFSIMTTSFSESTN

MGAM2

2196

Q2M2H8
MFNDFLSASSDTQTS

HMGCS2

316

P54868
SIENDTGTIYSTMSF

PCDH7

686

O60245
STMSFDREHQTTYTF

PCDH7

696

O60245
SGNDTISSSETVYMN

PPP2R3A

266

Q06190
YTATSDTQDSMSLLF

MED16

676

Q9Y2X0
ESYSDMSSQSFSETR

PRICKLE2

481

Q7Z3G6
SEDFNMGSSSSSQYT

CCPG1

131

Q9ULG6
MEFSSSTTHVQTFSQ

IGSF22

16

Q8N9C0
QDTYLSNSSMSNSYS

BRCA2

1736

P51587
SNSSMSNSYSYHSDE

BRCA2

1741

P51587
NSMVSTESASSTYEE

DSCAML1

1796

Q8TD84
MESNFNTESSSTFTL

CCDC73

1

Q6ZRK6
STSSMEDYVNFNFTD

CCR9

21

P51686
MNSISFYDGDSTSTV

DNAAF9

586

Q5TEA3
ADSTSVEAMYSVASQ

IRAK4

421

Q9NWZ3
SISSISESNMDYTAT

GABRP

71

O00591
NDTTNDNMSYSVEVS

KIF1A

131

Q12756
SVMATDQDSYSTSST

RIN3

541

Q8TB24
SASSTYSSAEERMQS

NAV1

1066

Q8NEY1
SSQSEAADQSMGYVS

RUSC2

256

Q8N2Y8
DSKTMTESFSFSSNV

TACR1

391

P25103
AFETNTTSYFNGTMD

SCN3A

286

Q9NY46
TSSEDEMAQSFSDYS

SHANK2

6

Q9UPX8
TAISENYQTMSDTTF

CAPZA2

241

P47755
SSLYTASEENSYMRS

TEX44

261

Q53QW1
VNNYTDFSGSSFEMT

TSPAN16

156

Q9UKR8
SSVSTMTSQYQEGDD

TPRX1

366

Q8N7U7
DNSVTSFTNESTYSM

REV3L

611

O60673
DTDMQASSYSSTSER

STAG3

1196

Q9UJ98
SQYSMVSDAETESIF

STYXL2

36

Q5VZP5
SIDFTTKTSYNSSSQ

ROBO2

976

Q9HCK4
MESSTNSSSQDYSTS

USP28

706

Q96RU2
TSTDSSYQMYHQSEA

USP38

866

Q8NB14
ASMFYEVSTRTSSSF

CAD

1966

P27708
DSHSYMINSNTYESS

ZGRF1

1081

Q86YA3
SNSFNSSYMSSDNES

WNK1

2051

Q9H4A3