| MousePheno | abnormal inguinal lymph node morphology | RUNX1 NFKB1 RAB13 HR | 7.54e-06 | 25 | 72 | 4 | MP:0002353 |
| Domain | MOZART2 | MZT2A MZT2B | 2.30e-05 | 2 | 90 | 2 | IPR024332 |
| Domain | MOZART2 | MZT2A MZT2B | 2.30e-05 | 2 | 90 | 2 | PF12926 |
| Domain | IQSEC_PH | IQSEC2 IQSEC1 | 6.87e-05 | 3 | 90 | 2 | IPR033742 |
| Domain | IQ_SEC7_PH | IQSEC2 IQSEC1 | 6.87e-05 | 3 | 90 | 2 | PF16453 |
| Domain | DEAD/DEAH_box_helicase_dom | DHX16 DDX47 DDX51 DDX39A | 4.26e-04 | 73 | 90 | 4 | IPR011545 |
| Domain | DEAD | DHX16 DDX47 DDX51 DDX39A | 4.26e-04 | 73 | 90 | 4 | PF00270 |
| Domain | WWE | TRIP12 PARP12 | 1.47e-03 | 12 | 90 | 2 | PS50918 |
| Domain | WWE | TRIP12 PARP12 | 1.47e-03 | 12 | 90 | 2 | PF02825 |
| Domain | WWE-dom | TRIP12 PARP12 | 1.47e-03 | 12 | 90 | 2 | IPR004170 |
| Domain | Helicase_C | DHX16 DDX47 DDX51 DDX39A | 1.78e-03 | 107 | 90 | 4 | PF00271 |
| Domain | HELICc | DHX16 DDX47 DDX51 DDX39A | 1.78e-03 | 107 | 90 | 4 | SM00490 |
| Domain | Helicase_C | DHX16 DDX47 DDX51 DDX39A | 1.84e-03 | 108 | 90 | 4 | IPR001650 |
| Domain | HELICASE_CTER | DHX16 DDX47 DDX51 DDX39A | 1.91e-03 | 109 | 90 | 4 | PS51194 |
| Domain | HELICASE_ATP_BIND_1 | DHX16 DDX47 DDX51 DDX39A | 1.91e-03 | 109 | 90 | 4 | PS51192 |
| Domain | DEXDc | DHX16 DDX47 DDX51 DDX39A | 1.91e-03 | 109 | 90 | 4 | SM00487 |
| Domain | Helicase_ATP-bd | DHX16 DDX47 DDX51 DDX39A | 1.97e-03 | 110 | 90 | 4 | IPR014001 |
| Domain | - | IQSEC2 IQSEC1 | 2.31e-03 | 15 | 90 | 2 | 1.10.1000.11 |
| Domain | Sec7 | IQSEC2 IQSEC1 | 2.31e-03 | 15 | 90 | 2 | PF01369 |
| Domain | Sec7_alpha_orthog | IQSEC2 IQSEC1 | 2.31e-03 | 15 | 90 | 2 | IPR023394 |
| Domain | Sec7 | IQSEC2 IQSEC1 | 2.64e-03 | 16 | 90 | 2 | SM00222 |
| Domain | SEC7 | IQSEC2 IQSEC1 | 2.64e-03 | 16 | 90 | 2 | PS50190 |
| Domain | Sec7_dom | IQSEC2 IQSEC1 | 2.64e-03 | 16 | 90 | 2 | IPR000904 |
| Domain | HSP70 | HSPA7 HSPA9 | 2.64e-03 | 16 | 90 | 2 | PF00012 |
| Domain | HSP70_2 | HSPA7 HSPA9 | 2.98e-03 | 17 | 90 | 2 | PS00329 |
| Domain | HSP70_3 | HSPA7 HSPA9 | 2.98e-03 | 17 | 90 | 2 | PS01036 |
| Domain | HSP70_1 | HSPA7 HSPA9 | 2.98e-03 | 17 | 90 | 2 | PS00297 |
| Domain | Hsp_70_fam | HSPA7 HSPA9 | 3.34e-03 | 18 | 90 | 2 | IPR013126 |
| Domain | - | PNKD MAP1S | 4.12e-03 | 20 | 90 | 2 | 3.60.15.10 |
| Domain | Metallo-B-lactamas | PNKD MAP1S | 4.12e-03 | 20 | 90 | 2 | IPR001279 |
| Pubmed | Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function. | DHX16 DDX47 OAS3 DDX51 RUNX1 TRIP12 ARHGEF40 NAT10 IQSEC1 DHRS2 DDX39A TIMM44 SNRPD3 RAB13 HSPA9 RPL8 PARP12 DNMT1 | 2.86e-08 | 1353 | 96 | 18 | 29467282 |
| Pubmed | FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2. | DHX16 OAS3 TRIP12 NAT10 TMPO TNKS1BP1 MTCL1 DHRS2 TIMM44 SNRPD3 RPL8 DNMT1 | 1.06e-07 | 601 | 96 | 12 | 33658012 |
| Pubmed | Systematic analysis of human protein complexes identifies chromosome segregation proteins. | DHX16 TSEN54 PNKD THBS1 ARID1B MAP1S RASSF1 TMPO TNKS1BP1 MZT2A CTNNA1 MTCL1 MZT2B DDX39A SNRPD3 | 6.36e-07 | 1155 | 96 | 15 | 20360068 |
| Pubmed | BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis. | DDX47 THBS1 KMT2D NAT10 TMPO CTNNA1 TIMM44 SNRPD3 HSPA9 RPL8 DNMT1 | 4.41e-06 | 711 | 96 | 11 | 33022573 |
| Pubmed | HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation. | DHX16 DDX47 RBM26 OAS3 TRIP12 ARHGEF40 NAT10 IQSEC1 TMPO DHRS2 TIMM44 SNRPD3 HSPA9 PARP12 DNMT1 | 5.22e-06 | 1371 | 96 | 15 | 36244648 |
| Pubmed | Single-cell architecture and functional requirement of alternative splicing during hematopoietic stem cell formation. | RUNX1 NFKB1 TMPO | 7.26e-06 | 14 | 96 | 3 | 34995116 |
| Pubmed | RUNX1 Plays an Important Role in Mediating BMP9-Induced Osteogenic Differentiation of Mesenchymal Stem Cells Line C3H10T1/2, Murine Multi-Lineage Cells Lines C2C12 and MEFs. | RUNX1 GDF2 | 7.54e-06 | 2 | 96 | 2 | 28644396 |
| Pubmed | Specificity of the methylation-suppressed A isoform of candidate tumor suppressor RASSF1 for microtubule hyperstabilization is determined by cell death inducer C19ORF5. | MAP1S RASSF1 | 7.54e-06 | 2 | 96 | 2 | 15753381 |
| Pubmed | P19INK4D links endomitotic arrest and megakaryocyte maturation and is regulated by AML-1. | CDKN2D RUNX1 | 7.54e-06 | 2 | 96 | 2 | 18276842 |
| Pubmed | Overexpression of myofibrillogenesis regulator-1 aggravates cardiac hypertrophy induced by angiotensin II in mice. | PNKD NFKB1 | 7.54e-06 | 2 | 96 | 2 | 17420335 |
| Pubmed | RASSF1A Enhances Chemosensitivity of NSCLC Cells Through Activating Autophagy by Regulating MAP1S to Inactivate Keap1-Nrf2 Pathway. | MAP1S RASSF1 | 7.54e-06 | 2 | 96 | 2 | 33442234 |
| Pubmed | The role of RUNX1/NF-κB in regulating PVAT inflammation in aortic dissection. | RUNX1 NFKB1 | 7.54e-06 | 2 | 96 | 2 | 38693222 |
| Pubmed | AML1/RUNX1 functions as a cytoplasmic attenuator of NF-κB signaling in the repression of myeloid tumors. | RUNX1 NFKB1 | 7.54e-06 | 2 | 96 | 2 | 22021368 |
| Pubmed | Methylation of RASSF1A gene promoter and the correlation with DNMT1 expression that may contribute to esophageal squamous cell carcinoma. | RASSF1 DNMT1 | 7.54e-06 | 2 | 96 | 2 | 25886188 |
| Pubmed | Hypermethylation of the thrombospondin-1 gene is associated with poor prognosis in penile squamous cell carcinoma. | THBS1 RASSF1 | 7.54e-06 | 2 | 96 | 2 | 18336597 |
| Pubmed | Upregulation of DNMT1 mediated by HBx suppresses RASSF1A expression independent of DNA methylation. | RASSF1 DNMT1 | 7.54e-06 | 2 | 96 | 2 | 24247422 |
| Pubmed | GEP100/BRAG2: activator of ADP-ribosylation factor 6 for regulation of cell adhesion and actin cytoskeleton via E-cadherin and alpha-catenin. | IQSEC1 CTNNA1 | 7.54e-06 | 2 | 96 | 2 | 16807291 |
| Pubmed | Thrombospondin 1 and Nuclear Factor Kappa B Signaling Pathways in Non-alcoholic Fatty Liver Disease. | THBS1 NFKB1 | 7.54e-06 | 2 | 96 | 2 | 36112712 |
| Pubmed | Large-scale characterization of HeLa cell nuclear phosphoproteins. | DHX16 DDX51 RUNX1 TRIP12 KMT2D MAP1S IQSEC1 TMPO TNKS1BP1 CTNNA1 DNMT1 | 9.79e-06 | 774 | 96 | 11 | 15302935 |
| Pubmed | RECQ1 helicase is involved in replication stress survival and drug resistance in multiple myeloma. | DHX16 DDX47 RUNX1 TMPO DDX39A HSPA7 | 1.22e-05 | 183 | 96 | 6 | 28186131 |
| Pubmed | MZT Proteins Form Multi-Faceted Structural Modules in the γ-Tubulin Ring Complex. | MZT2A MZT2B | 2.26e-05 | 3 | 96 | 2 | 32610146 |
| Pubmed | ER stress activates NF-κB by integrating functions of basal IKK activity, IRE1 and PERK. | NFKB1 EIF2AK3 | 2.26e-05 | 3 | 96 | 2 | 23110043 |
| Pubmed | Silencing DNA methyltransferase 1 (DNMT1) inhibits proliferation, metastasis and invasion in ESCC by suppressing methylation of RASSF1A and DAPK. | RASSF1 DNMT1 | 2.26e-05 | 3 | 96 | 2 | 27286455 |
| Pubmed | The tumor suppressor gene, RASSF1A, is essential for protection against inflammation -induced injury. | RASSF1 NFKB1 | 2.26e-05 | 3 | 96 | 2 | 24146755 |
| Pubmed | Mahanine restores RASSF1A expression by down-regulating DNMT1 and DNMT3B in prostate cancer cells. | RASSF1 DNMT1 | 2.26e-05 | 3 | 96 | 2 | 24001151 |
| Pubmed | DNA methylation-dependent regulation of BORIS/CTCFL expression in ovarian cancer. | CTCFL DNMT1 | 2.26e-05 | 3 | 96 | 2 | 18095639 |
| Pubmed | Developmental trajectory of prehematopoietic stem cell formation from endothelium. | SOX17 RUNX1 | 2.26e-05 | 3 | 96 | 2 | 32392346 |
| Pubmed | Increased expression of GGN promotes tumorigenesis in bladder cancer and is correlated with poor prognosis. | GGN NFKB1 | 2.26e-05 | 3 | 96 | 2 | 29412153 |
| Pubmed | Early epigenetic downregulation of WNK2 kinase during pancreatic ductal adenocarcinoma development. | PTF1A WNK2 | 2.26e-05 | 3 | 96 | 2 | 23912455 |
| Pubmed | Association between SOX17, Wif-1 and RASSF1A promoter methylation status and response to chemotherapy in patients with metastatic gastric cancer. | SOX17 RASSF1 | 2.26e-05 | 3 | 96 | 2 | 32870805 |
| Pubmed | Mahanine reverses an epigenetically silenced tumor suppressor gene RASSF1A in human prostate cancer cells. | RASSF1 DNMT1 | 2.26e-05 | 3 | 96 | 2 | 17698033 |
| Pubmed | CTNNA1 hypermethylation, a frequent event in acute myeloid leukemia, is independently associated with an adverse outcome. | RUNX1 CTNNA1 | 2.26e-05 | 3 | 96 | 2 | 27129146 |
| Pubmed | Age-Dependent Alterations in the Interactions of NF-κB and N-myc with GLT-1/EAAT2 Promoter in the Pericontusional Cortex of Mice Subjected to Traumatic Brain Injury. | SLC1A2 NFKB1 | 2.26e-05 | 3 | 96 | 2 | 26081154 |
| Pubmed | Inhibin α-subunit inhibits BMP9-induced osteogenic differentiation through blocking BMP/Smad signal and activating NF-κB signal in mesenchymal stem cells. | GDF2 NFKB1 | 2.26e-05 | 3 | 96 | 2 | 29923343 |
| Pubmed | RASSF1A interacts with microtubule-associated proteins and modulates microtubule dynamics. | MAP1S RASSF1 | 2.26e-05 | 3 | 96 | 2 | 15205320 |
| Pubmed | Prognostic Role of RASSF1A, SOX17 and Wif-1 Promoter Methylation Status in Cell-Free DNA of Advanced Gastric Cancer Patients. | SOX17 RASSF1 | 2.26e-05 | 3 | 96 | 2 | 33928818 |
| Pubmed | A tetratricopeptide repeat-containing protein gene, tpis, whose expression is induced with differentiation of spermatogenic cells. | SPAG1 LHX8 | 2.26e-05 | 3 | 96 | 2 | 10527845 |
| Pubmed | Interplay of RUNX1/MTG8 and DNA methyltransferase 1 in acute myeloid leukemia. | RUNX1 DNMT1 | 2.26e-05 | 3 | 96 | 2 | 15735013 |
| Pubmed | Runt-related Transcription Factor 1 (RUNX1) Binds to p50 in Macrophages and Enhances TLR4-triggered Inflammation and Septic Shock. | RUNX1 NFKB1 | 2.26e-05 | 3 | 96 | 2 | 27573239 |
| Pubmed | Functional specialization of beta-arrestin interactions revealed by proteomic analysis. | STXBP5 TMPO RAB11FIP5 CTNNA1 DHRS2 HSPA7 HSPA9 | 2.91e-05 | 317 | 96 | 7 | 17620599 |
| Pubmed | A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. | DHX16 DDX47 IQSEC2 RBM26 RASSF1 PI4KB NFKB1 IQSEC1 RAB11FIP5 TNKS1BP1 RPL8 PARP12 | 2.93e-05 | 1038 | 96 | 12 | 26673895 |
| Pubmed | Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice. | DDX47 TRIP12 NAT10 TMPO TNKS1BP1 CTNNA1 MTCL1 DDX39A SNRPD3 | 3.45e-05 | 582 | 96 | 9 | 20467437 |
| Pubmed | E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins. | TOPAZ1 IQSEC2 NAGLU CSMD2 ZNF831 TRIP12 PRR35 GIMAP8 TMPO MTCL1 | 3.72e-05 | 736 | 96 | 10 | 29676528 |
| Pubmed | Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma. | DHX16 DDX47 OAS3 TRIP12 THBS1 NAT10 TMPO TNKS1BP1 CTNNA1 SNRPD3 HSPA9 RPL8 DNMT1 | 4.22e-05 | 1257 | 96 | 13 | 36526897 |
| Pubmed | Regulated cycling of mitochondrial Hsp70 at the protein import channel. | TIMM44 HSPA9 | 4.51e-05 | 4 | 96 | 2 | 12677068 |
| Pubmed | Identification and manipulation of biliary metaplasia in pancreatic tumors. | PTF1A SOX17 | 4.51e-05 | 4 | 96 | 2 | 23999170 |
| Pubmed | Subunit-selective N-Methyl-d-aspartate (NMDA) Receptor Signaling through Brefeldin A-resistant Arf Guanine Nucleotide Exchange Factors BRAG1 and BRAG2 during Synapse Maturation. | IQSEC2 IQSEC1 | 4.51e-05 | 4 | 96 | 2 | 26884337 |
| Pubmed | Identification of rare sequence variation underlying heritable pulmonary arterial hypertension. | SOX17 GDF2 | 4.51e-05 | 4 | 96 | 2 | 29650961 |
| Pubmed | Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. | STXBP5 SLC1A2 AMER2 IQSEC1 RAB11FIP5 TNKS1BP1 CTNNA1 | 5.16e-05 | 347 | 96 | 7 | 17114649 |
| Pubmed | PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα. | RBM26 RUNX1 THAP4 ARID1B KMT2D TMPO MZT2B DDX39A SNRPD3 HSPA9 DNMT1 ZNF121 | 5.26e-05 | 1103 | 96 | 12 | 34189442 |
| Pubmed | The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA. | DDX47 DDX51 TRIP12 NAT10 TMPO DDX39A DNMT1 | 5.35e-05 | 349 | 96 | 7 | 25665578 |
| Pubmed | Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer. | DDX47 RUNX1 C4orf54 TMPO TNKS1BP1 SNRPD3 RAB13 HSPA9 RPL8 | 6.04e-05 | 626 | 96 | 9 | 33644029 |
| Pubmed | Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents. | DHX16 DDX47 NAT10 TMPO HSPA7 HSPA9 RPL8 DNMT1 | 6.21e-05 | 486 | 96 | 8 | 30940648 |
| Pubmed | TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1. | DDX47 DDX51 NAT10 RAB11FIP5 CTNNA1 DDX39A SNRPD3 HSPA7 RAB13 HSPA9 RPL8 | 6.29e-05 | 949 | 96 | 11 | 36574265 |
| Pubmed | BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression. | DHX16 DDX47 TRIP12 NAT10 IQSEC1 TMPO DDX39A TIMM44 SNRPD3 RAB13 HSPA9 RPL8 DNMT1 | 6.82e-05 | 1318 | 96 | 13 | 30463901 |
| Pubmed | Differentiation of the epithelial apical junctional complex during mouse preimplantation development: a role for rab13 in the early maturation of the tight junction. | CTNNA1 RAB13 | 7.50e-05 | 5 | 96 | 2 | 11025210 |
| Pubmed | Methylation of RASSF1A gene promoter is regulated by p53 and DAXX. | RASSF1 DNMT1 | 7.50e-05 | 5 | 96 | 2 | 23038753 |
| Pubmed | DLL4/Notch1 and BMP9 Interdependent Signaling Induces Human Endothelial Cell Quiescence via P27KIP1 and Thrombospondin-1. | GDF2 THBS1 | 7.50e-05 | 5 | 96 | 2 | 26471266 |
| Pubmed | Transcriptional regulatory network controlling the ontogeny of hematopoietic stem cells. | SOX17 RUNX1 | 7.50e-05 | 5 | 96 | 2 | 32499402 |
| Pubmed | DNA methyltransferase 1 and 3B activate BAG-1 expression via recruitment of CTCFL/BORIS and modulation of promoter histone methylation. | CTCFL DNMT1 | 7.50e-05 | 5 | 96 | 2 | 18413740 |
| Pubmed | Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase. | GSR TMPO TNKS1BP1 SNRPD3 HSPA9 RPL8 | 7.99e-05 | 256 | 96 | 6 | 32698014 |
| Pubmed | Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. | DHX16 DDX51 TRIP12 NAT10 TNKS1BP1 CTNNA1 HSPA9 RPL8 DNMT1 | 8.33e-05 | 653 | 96 | 9 | 22586326 |
| Pubmed | Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2. | DHX16 P3H3 OAS3 DHRS2 HSPA9 | 8.69e-05 | 161 | 96 | 5 | 32572027 |
| Pubmed | A protein-RNA interaction atlas of the ribosome biogenesis factor AATF. | DHX16 DDX47 RBM26 NAT10 RPL8 | 8.95e-05 | 162 | 96 | 5 | 31363146 |
| Pubmed | AMPA receptor signaling through BRAG2 and Arf6 critical for long-term synaptic depression. | IQSEC2 IQSEC1 | 1.12e-04 | 6 | 96 | 2 | 20547133 |
| Pubmed | Positive and negative regulation of EAAT2 by NF-kappaB: a role for N-myc in TNFalpha-controlled repression. | SLC1A2 NFKB1 | 1.12e-04 | 6 | 96 | 2 | 15660126 |
| Pubmed | Cloning of the gene for spinocerebellar ataxia 2 reveals a locus with high sensitivity to expanded CAG/glutamine repeats. | ARID1B KMT2D | 1.12e-04 | 6 | 96 | 2 | 8896557 |
| Pubmed | Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage. | CPPED1 PLEKHH3 GSR NAT10 TNKS1BP1 CTNNA1 DHRS2 SNRPD3 HSPA7 HSPA9 | 1.16e-04 | 844 | 96 | 10 | 25963833 |
| Pubmed | Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes. | RAB11FIP5 TNKS1BP1 CTNNA1 TIMM44 FAM8A1 HSPA7 HSPA9 DNMT1 | 1.18e-04 | 533 | 96 | 8 | 25544563 |
| Pubmed | ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1. | P3H3 NAGLU GSR THBS1 ALG9 TMPO TNKS1BP1 ALG3 CTNNA1 EIF2AK3 FAM8A1 DNMT1 | 1.18e-04 | 1201 | 96 | 12 | 35696571 |
| Pubmed | Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease. | RUNX1 GDF2 THBS1 NFKB1 | 1.37e-04 | 94 | 96 | 4 | 20346360 |
| Pubmed | Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells. | DHX16 RBM26 TRIP12 NAT10 TMPO DNMT1 | 1.38e-04 | 283 | 96 | 6 | 30585729 |
| Pubmed | HEY1 functions are regulated by its phosphorylation at Ser-68. | IQSEC1 TNKS1BP1 SNRPD3 RPL8 | 1.43e-04 | 95 | 96 | 4 | 27129302 |
| Pubmed | SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway. | RBM26 ARID1B KMT2D NAT10 TMPO TNKS1BP1 WIPI2 DNMT1 | 1.44e-04 | 549 | 96 | 8 | 38280479 |
| Pubmed | A Noncanonical Role of Fructose-1, 6-Bisphosphatase 1 Is Essential for Inhibition of Notch1 in Breast Cancer. | OAS3 NFKB1 TMPO SNRPD3 HSPA9 RPL8 | 1.46e-04 | 286 | 96 | 6 | 32041737 |
| Pubmed | Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators. | NAGLU C2CD4C ARID1B KMT2D TBC1D31 NFKB1 NAT10 TMPO RAB11FIP5 CTNNA1 DNMT1 | 1.52e-04 | 1049 | 96 | 11 | 27880917 |
| Pubmed | Efficient derivation of extraembryonic endoderm stem cell lines from mouse postimplantation embryos. | SOX17 DNMT1 | 1.57e-04 | 7 | 96 | 2 | 27991575 |
| Pubmed | Thbs1 induces lethal cardiac atrophy through PERK-ATF4 regulated autophagy. | THBS1 EIF2AK3 | 1.57e-04 | 7 | 96 | 2 | 34168130 |
| Pubmed | Molecular basis of T cell-mediated recognition of pancreatic cancer cells. | OAS3 WNK2 | 1.57e-04 | 7 | 96 | 2 | 11280764 |
| Pubmed | Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. | ZCCHC2 NAT10 TNKS1BP1 WNK2 | 1.88e-04 | 102 | 96 | 4 | 11214970 |
| Pubmed | MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons. | DHX16 DDX47 TRIP12 ARID1B NAT10 IQSEC1 TMPO TNKS1BP1 DDX39A SNRPD3 RPL8 | 1.98e-04 | 1082 | 96 | 11 | 38697112 |
| Pubmed | Intronic miR-3151 within BAALC drives leukemogenesis by deregulating the TP53 pathway. | RUNX1 NFKB1 | 2.09e-04 | 8 | 96 | 2 | 24736457 |
| Pubmed | Dominant and context-specific control of endodermal organ allocation by Ptf1a. | PTF1A SOX17 | 2.09e-04 | 8 | 96 | 2 | 25371369 |
| Pubmed | Role of Magmas in protein transport and human mitochondria biogenesis. | TIMM44 HSPA9 | 2.09e-04 | 8 | 96 | 2 | 20053669 |
| Pubmed | Network organization of the human autophagy system. | RBM26 MAP1S RASSF1 PI4KB TMPO DDX39A WIPI2 | 2.15e-04 | 437 | 96 | 7 | 20562859 |
| Pubmed | H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids. | DDX47 DDX51 RUNX1 TRIP12 THAP4 KMT2D NAT10 TMPO SNRPD3 HSPA9 RPL8 DNMT1 | 2.34e-04 | 1294 | 96 | 12 | 30804502 |
| Pubmed | Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. | DDX47 ZCWPW1 ZNF280D ZCCHC2 ALG9 NAT10 WIPI2 ZNF541 PARP12 | 2.35e-04 | 750 | 96 | 9 | 11230166 |
| Pubmed | Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling. | DHX16 P3H3 TRIP12 GSR ARHGEF40 MAP1S TNKS1BP1 MTCL1 DDX39A RAB13 HSPA9 DNMT1 | 2.39e-04 | 1297 | 96 | 12 | 33545068 |
| Pubmed | LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy. | TRIP12 THBS1 ARHGEF40 TMPO DNMT1 | 2.50e-04 | 202 | 96 | 5 | 33005030 |
| Pubmed | STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production. | DDX47 DDX51 NAT10 DDX39A HSPA9 RPL8 | 2.51e-04 | 316 | 96 | 6 | 31665637 |
| Pubmed | N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective. | RBM26 GSR NAT10 TMPO TNKS1BP1 SNRPD3 HSPA9 RPL8 PARP12 DNMT1 | 2.61e-04 | 934 | 96 | 10 | 33916271 |
| Pubmed | Emergence of hematopoietic stem and progenitor cells involves a Chd1-dependent increase in total nascent transcription. | SOX17 RUNX1 | 2.68e-04 | 9 | 96 | 2 | 25831528 |
| Pubmed | CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality. | DDX47 DDX51 NAT10 TMPO DDX39A SNRPD3 HSPA9 RPL8 | 2.77e-04 | 605 | 96 | 8 | 28977666 |
| Pubmed | Directed proteomic analysis of the human nucleolus. | DDX51 DDX39A SNRPD3 HSPA9 RPL8 | 2.87e-04 | 208 | 96 | 5 | 11790298 |
| Pubmed | ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication. | DDX47 SCARF2 PI4KB ALG9 TMPO CTNNA1 EIF2AK3 RAB13 HSPA9 RPL8 | 3.04e-04 | 952 | 96 | 10 | 38569033 |
| Pubmed | Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB. | SCARF2 C2CD4C TRIP12 PI4KB TMPO RAB11FIP5 HSPA9 RPL8 DNMT1 | 3.04e-04 | 777 | 96 | 9 | 35844135 |
| Pubmed | The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4. | THBS1 NFKB1 TNKS1BP1 CTNNA1 MTCL1 DNMT1 | 3.26e-04 | 332 | 96 | 6 | 37433992 |
| Pubmed | Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression. | DHX16 DDX47 DDX51 TRIP12 NAT10 TNKS1BP1 | 3.26e-04 | 332 | 96 | 6 | 25693804 |
| Pubmed | Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells. | ZNF831 TRIP12 KMT2D NFKB1 TNKS1BP1 CTNNA1 DNMT1 | 3.29e-04 | 469 | 96 | 7 | 27634302 |
| Pubmed | Let-7 microRNA-dependent control of leukotriene signaling regulates the transition of hematopoietic niche in mice. | SOX17 RUNX1 | 3.34e-04 | 10 | 96 | 2 | 28743859 |
| GeneFamily | Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing | C2CD4C C2CD4D RAB11FIP5 | 1.87e-04 | 36 | 56 | 3 | 823 |
| GeneFamily | DEAD-box helicases | DDX47 DDX51 DDX39A | 2.97e-04 | 42 | 56 | 3 | 499 |
| GeneFamily | Dolichyl D-mannosyl phosphate dependent mannosyltransferases|Phosphatidylinositol glycan anchor biosynthesis | ALG9 ALG3 | 3.35e-04 | 9 | 56 | 2 | 430 |
| GeneFamily | Heat shock 70kDa proteins | HSPA7 HSPA9 | 1.24e-03 | 17 | 56 | 2 | 583 |
| Disease | lung non-small cell carcinoma (is_implicated_in) | ARID1B KMT2D RASSF1 NFKB1 DNMT1 | 8.04e-05 | 139 | 93 | 5 | DOID:3908 (is_implicated_in) |
| Disease | Influenza | OAS3 ZCCHC2 PARP12 | 5.99e-04 | 52 | 93 | 3 | C0021400 |
| Disease | intracranial aneurysm (is_implicated_in) | SOX17 KMT2D | 6.35e-04 | 12 | 93 | 2 | DOID:10941 (is_implicated_in) |
| Disease | 2-oxo-hept-3-ene-1,7-dioate hydratase activity | SOX17 GDF2 | 8.72e-04 | 14 | 93 | 2 | C1150929 |
| Disease | Familial primary pulmonary hypertension | SOX17 GDF2 | 1.30e-03 | 17 | 93 | 2 | C0340543 |
| Disease | reticulocyte count | PNKD TMEM91 ADRB1 GIMAP8 RASSF1 NFKB1 SPOCD1 DDX39A WIPI2 DNMT1 | 1.68e-03 | 1045 | 93 | 10 | EFO_0007986 |
| Disease | Mood Disorders | SLC1A2 ADRB1 NFKB1 DNMT1 | 2.00e-03 | 168 | 93 | 4 | C0525045 |
| Disease | lung non-small cell carcinoma (is_marker_for) | RUNX1 NFKB1 IQSEC1 DNMT1 | 2.04e-03 | 169 | 93 | 4 | DOID:3908 (is_marker_for) |
| Disease | Epilepsy, Cryptogenic | IQSEC2 SLC1A2 ARID1B | 2.24e-03 | 82 | 93 | 3 | C0086237 |
| Disease | Awakening Epilepsy | IQSEC2 SLC1A2 ARID1B | 2.24e-03 | 82 | 93 | 3 | C0751111 |
| Disease | Aura | IQSEC2 SLC1A2 ARID1B | 2.24e-03 | 82 | 93 | 3 | C0236018 |
| Disease | Myocardial Ischemia | ADRB1 TMPO EIF2AK3 HSPA9 | 2.36e-03 | 176 | 93 | 4 | C0151744 |
| Disease | Hereditary Diffuse Gastric Cancer | CDKN2D SLC1A2 ADRB1 CTNNA1 DNMT1 | 2.38e-03 | 293 | 93 | 5 | C1708349 |
| Disease | generalized anxiety disorder | LHX8 CTNNA1 | 2.38e-03 | 23 | 93 | 2 | EFO_1001892 |
| Disease | Neonatal diabetes mellitus | PTF1A EIF2AK3 | 2.81e-03 | 25 | 93 | 2 | C0158981 |
