Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	fructose-bisphosphate aldolase activity	ALDOA ALDOB ALDOC	2.99e-08	3	63	3	GO:0004332
GeneOntologyMolecularFunction	aldehyde-lyase activity	ALDOA ALDOB ALDOC	4.85e-06	11	63	3	GO:0016832
GeneOntologyMolecularFunction	cytoskeletal protein binding	SLC6A4 RANBP10 FLNA ABI3BP GLI1 LMTK2 DIXDC1 ALDOA ALDOB ALDOC VASP KIF1C	1.43e-04	1099	63	12	GO:0008092
GeneOntologyMolecularFunction	fructose binding	ALDOA ALDOB	1.46e-04	6	63	2	GO:0070061
GeneOntologyMolecularFunction	ATP hydrolysis activity	DDX52 PEX6 ATP13A5 DDX56 ABCD1 MORC4 KIF1C	4.65e-04	441	63	7	GO:0016887
GeneOntologyMolecularFunction	SH2 domain binding	AFAP1L2 SIGLEC16 SIGLEC11	5.92e-04	52	63	3	GO:0042169
GeneOntologyMolecularFunction	carbon-carbon lyase activity	ALDOA ALDOB ALDOC	7.36e-04	56	63	3	GO:0016830
GeneOntologyMolecularFunction	RNA stem-loop binding	RC3H1 DDX56	1.98e-03	21	63	2	GO:0035613
GeneOntologyMolecularFunction	collagen binding	HSPG2 VWF ABI3BP	2.14e-03	81	63	3	GO:0005518
GeneOntologyMolecularFunction	protease binding	HSPG2 VWF ALDOA COL1A1	2.56e-03	181	63	4	GO:0002020
GeneOntologyMolecularFunction	sialic acid binding	SIGLEC16 SIGLEC11	2.80e-03	25	63	2	GO:0033691
GeneOntologyMolecularFunction	extracellular matrix structural constituent	HSPG2 VWF ABI3BP COL1A1	2.94e-03	188	63	4	GO:0005201
GeneOntologyMolecularFunction	carbohydrate binding	KRT1 SIGLEC16 SIGLEC11 ALDOA ALDOB	2.94e-03	310	63	5	GO:0030246
GeneOntologyMolecularFunction	ATP-dependent activity	DDX52 PEX6 ATP13A5 DDX56 ABCD1 MORC4 KIF1C	3.13e-03	614	63	7	GO:0140657
GeneOntologyBiologicalProcess	fructose 1,6-bisphosphate metabolic process	ALDOA ALDOB ALDOC	2.36e-06	9	64	3	GO:0030388
GeneOntologyBiologicalProcess	fructose metabolic process	ALDOA ALDOB ALDOC	1.55e-05	16	64	3	GO:0006000
HumanPheno	Reduced circulating aldolase concentration	ALDOA ALDOB	1.32e-05	2	19	2	HP:0012545
Domain	FBA_I	ALDOA ALDOB ALDOC	3.48e-08	3	62	3	IPR000741
Domain	Glycolytic	ALDOA ALDOB ALDOC	3.48e-08	3	62	3	PF00274
Domain	Aldolase_I_AS	ALDOA ALDOB ALDOC	3.48e-08	3	62	3	IPR029768
Domain	ALDOLASE_CLASS_I	ALDOA ALDOB ALDOC	3.48e-08	3	62	3	PS00158
Domain	-	TGM4 HSPG2 FLNA ABI3BP BTNL8 HLA-DOA FSD2 SIGLEC11 PKHD1L1 ALPK2	6.02e-05	663	62	10	2.60.40.10
Domain	Ig-like_fold	TGM4 HSPG2 FLNA ABI3BP BTNL8 HLA-DOA FSD2 SIGLEC11 PKHD1L1 ALPK2	1.01e-04	706	62	10	IPR013783
Domain	-	ALDOA ALDOB ALDOC	3.65e-04	42	62	3	3.20.20.70
Domain	Aldolase_TIM	ALDOA ALDOB ALDOC	4.19e-04	44	62	3	IPR013785
Pathway	REACTOME_GP1B_IX_V_ACTIVATION_SIGNALLING	FLNA VWF COL1A1	8.49e-06	12	49	3	MM15093
Pathway	REACTOME_GP1B_IX_V_ACTIVATION_SIGNALLING	FLNA VWF COL1A1	8.49e-06	12	49	3	M27352
Pathway	KEGG_MEDICUS_REFERENCE_GLYCOLYSIS	ALDOA ALDOB ALDOC	8.60e-05	25	49	3	M47623
Pathway	REACTOME_GLUCONEOGENESIS	ALDOA ALDOB ALDOC	9.70e-05	26	49	3	MM15392
Pathway	REACTOME_GLUCONEOGENESIS	ALDOA ALDOB ALDOC	9.70e-05	26	49	3	M13748
Pathway	KEGG_PENTOSE_PHOSPHATE_PATHWAY	ALDOA ALDOB ALDOC	1.09e-04	27	49	3	M1386
Pathway	KEGG_FRUCTOSE_AND_MANNOSE_METABOLISM	ALDOA ALDOB ALDOC	2.19e-04	34	49	3	M15898
Pathway	REACTOME_ENHANCED_BINDING_OF_GP1BA_VARIANT_TO_VWF_MULTIMER_COLLAGEN	VWF COL1A1	2.46e-04	7	49	2	M48265
Pathway	REACTOME_DEFECTS_OF_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN	VWF COL1A1	3.27e-04	8	49	2	M48236
Pathway	WP_GLYCOLYSIS_AND_GLUCONEOGENESIS	ALDOA ALDOB ALDOC	5.05e-04	45	49	3	M39474
Pathway	WP_GLYCOLYSIS_AND_GLUCONEOGENESIS	ALDOA ALDOB ALDOC	7.31e-04	51	49	3	MM15928
Pathway	REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN	VWF COL1A1	7.64e-04	12	49	2	MM15452
Pathway	REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2	FLNA VWF NHLRC2 ALDOA	1.06e-03	130	49	4	MM15455
Pathway	REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2	FLNA VWF NHLRC2 ALDOA	1.12e-03	132	49	4	M724
Pathway	KEGG_GLYCOLYSIS_GLUCONEOGENESIS	ALDOA ALDOB ALDOC	1.29e-03	62	49	3	M11521
Pathway	REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN	VWF COL1A1	1.38e-03	16	49	2	M9450
Pathway	REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS	FLNA VASP	1.75e-03	18	49	2	MM15123
Pathway	REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS	FLNA VASP	1.75e-03	18	49	2	M840
Pathway	REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION	FLNA VWF NHLRC2 ALDOA COL1A1	1.92e-03	257	49	5	MM15454
Pathway	REACTOME_DISEASES_OF_HEMOSTASIS	VWF COL1A1	1.95e-03	19	49	2	M48230
Pathway	REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION	FLNA VWF NHLRC2 ALDOA COL1A1	2.05e-03	261	49	5	M1077
Pathway	REACTOME_HEMOSTASIS	FLNA VWF DOCK11 IRF2 NHLRC2 ALDOA KIF1C COL1A1	2.17e-03	679	49	8	M8395
Pubmed	Mode of interactions of human aldolase isozymes with cytoskeletons.	ALDOA ALDOB ALDOC	5.94e-09	3	64	3	9244396
Pubmed	Aldolase positively regulates of the canonical Wnt signaling pathway.	ALDOA ALDOB ALDOC	5.94e-09	3	64	3	24993527
Pubmed	Human skeletal-muscle aldolase: N-terminal sequence analysis of CNBr- and o-iodosobenzoic acid-cleavage fragments.	ALDOA ALDOB ALDOC	5.94e-09	3	64	3	6696436
Pubmed	Interaction between aldolase and vacuolar H+-ATPase: evidence for direct coupling of glycolysis to the ATP-hydrolyzing proton pump.	ALDOA ALDOB ALDOC	2.37e-08	4	64	3	11399750
Pubmed	Rewiring of embryonic glucose metabolism via suppression of PFK-1 and aldolase during mouse chorioallantoic branching.	ALDOA ALDOB ALDOC COL1A1	3.13e-08	18	64	4	28049690
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	USP34 RANBP10 HSPG2 FLNA SEPHS2 GLI1 LMTK2 PEX6 DDX56 ABCD1 SNAPC4 FAAP100 COL1A1	9.16e-08	1105	64	13	35748872
Pubmed	Developmental basis for filamin-A-associated myxomatous mitral valve disease.	SLC6A4 FLNA COL1A1	9.70e-07	11	64	3	22843703
Pubmed	Structure and expression of mouse aldolase genes. Brain-specific aldolase C amino acid sequence is closely related to aldolase A.	ALDOA ALDOC	3.33e-06	2	64	2	3009179
Pubmed	Aldolase-B knockout in mice phenocopies hereditary fructose intolerance in humans.	ALDOA ALDOB	3.33e-06	2	64	2	25637246
Pubmed	A human-specific gene in microglia.	SIGLEC16 SIGLEC11	3.33e-06	2	64	2	16151003
Pubmed	SIGLEC16 encodes a DAP12-associated receptor expressed in macrophages that evolved from its inhibitory counterpart SIGLEC11 and has functional and non-functional alleles in humans.	SIGLEC16 SIGLEC11	3.33e-06	2	64	2	18629938
Pubmed	An analysis of expression patterns of genes encoding proteins with catalytic activities.	SUCLG1 ALDOA ALDOB ALDOC	7.32e-06	67	64	4	17626619
Pubmed	SIGLEC-G deficiency increases susceptibility to develop B-cell lymphoproliferative disorders.	SIGLEC16 SIGLEC11	9.99e-06	3	64	2	24859880
Pubmed	The role of Siglec-G on B cells in autoimmune disease and leukemia.	SIGLEC16 SIGLEC11	9.99e-06	3	64	2	38042621
Pubmed	Visualization of individual cell division history in complex tissues using iCOUNT.	GLI1 COL1A1	9.99e-06	3	64	2	34525348
Pubmed	The ligand-binding domain of Siglec-G is crucial for its selective inhibitory function on B1 cells.	SIGLEC16 SIGLEC11	9.99e-06	3	64	2	24790146
Pubmed	Isolation and characterization of a collagen binding domain in human von Willebrand factor.	VWF COL1A1	9.99e-06	3	64	2	3490481
Pubmed	Siglec-G is a B1 cell-inhibitory receptor that controls expansion and calcium signaling of the B1 cell population.	SIGLEC16 SIGLEC11	9.99e-06	3	64	2	17572677
Pubmed	Phospholipase D2 directly interacts with aldolase via Its PH domain.	ALDOA ALDOC	9.99e-06	3	64	2	11876650
Pubmed	Copresentation of antigen and ligands of Siglec-G induces B cell tolerance independent of CD22.	SIGLEC16 SIGLEC11	9.99e-06	3	64	2	23836061
Pubmed	Factor VIII/von Willebrand factor in subendothelium mediates platelet adhesion.	VWF COL1A1	9.99e-06	3	64	2	3872140
Pubmed	Siglecg limits the size of B1a B cell lineage by down-regulating NFkappaB activation.	SIGLEC16 SIGLEC11	2.00e-05	4	64	2	17912374
Pubmed	Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo.	SIGLEC16 SIGLEC11	2.00e-05	4	64	2	20038598
Pubmed	CD22 x Siglec-G double-deficient mice have massively increased B1 cell numbers and develop systemic autoimmunity.	SIGLEC16 SIGLEC11	2.00e-05	4	64	2	20200274
Pubmed	Siglec-G regulates B1 cell survival and selection.	SIGLEC16 SIGLEC11	2.00e-05	4	64	2	20729333
Pubmed	Sialic Acid Ligand Binding of CD22 and Siglec-G Determines Distinct B Cell Functions but Is Dispensable for B Cell Tolerance Induction.	SIGLEC16 SIGLEC11	2.00e-05	4	64	2	30143587
Pubmed	Siglec-G-CD24 axis controls the severity of graft-versus-host disease in mice.	SIGLEC16 SIGLEC11	2.00e-05	4	64	2	24695850
Pubmed	Siglecs induce tolerance to cell surface antigens by BIM-dependent deletion of the antigen-reactive B cells.	SIGLEC16 SIGLEC11	2.00e-05	4	64	2	25252961
Pubmed	Siglec-G deficiency leads to more severe collagen-induced arthritis and earlier onset of lupus-like symptoms in MRL/lpr mice.	SIGLEC16 SIGLEC11	2.00e-05	4	64	2	24600033
Pubmed	Identification of novel candidate genes in heterotaxy syndrome patients with congenital heart diseases by whole exome sequencing.	FLNA GLI1	2.00e-05	4	64	2	32738303
Pubmed	Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.	SUCLG1 ALDOA ALDOB ALDOC	2.69e-05	93	64	4	27215380
Pubmed	Structure and location of the murine adrenoleukodystrophy gene.	FLNA ABCD1	3.32e-05	5	64	2	8838803
Pubmed	Heparanase, heparan sulfate and perlecan distribution along with the vascular penetration during stellate reticulum retraction in the mouse enamel organ.	HSPG2 VWF	3.32e-05	5	64	2	20684947
Pubmed	Epistatic effects of Siglec-G and DNase1 or DNase1l3 deficiencies in the development of systemic lupus erythematosus.	SIGLEC16 SIGLEC11	3.32e-05	5	64	2	36969253
Pubmed	CD24 and Siglec-10 selectively repress tissue damage-induced immune responses.	SIGLEC16 SIGLEC11	3.32e-05	5	64	2	19264983
Pubmed	Evolutionary implications of the human aldolase-A, -B, -C, and -pseudogene chromosome locations.	ALDOA ALDOC	3.32e-05	5	64	2	3674018
Pubmed	Siglec-G Deficiency Leads to Autoimmunity in Aging C57BL/6 Mice.	SIGLEC16 SIGLEC11	3.32e-05	5	64	2	25987743
Pubmed	B Lymphocyte-Derived CCL7 Augments Neutrophil and Monocyte Recruitment, Exacerbating Acute Kidney Injury.	SIGLEC16 SIGLEC11	3.32e-05	5	64	2	32737150
Pubmed	The lectin Siglec-G inhibits dendritic cell cross-presentation by impairing MHC class I-peptide complex formation.	SIGLEC16 SIGLEC11	3.32e-05	5	64	2	27548433
Pubmed	Sialic Acid-Binding Immunoglobulin-like Lectin G Promotes Atherosclerosis and Liver Inflammation by Suppressing the Protective Functions of B-1 Cells.	SIGLEC16 SIGLEC11	3.32e-05	5	64	2	26947073
Pubmed	A hypomorphic IgH-chain allele affects development of B-cell subsets and favours receptor editing.	SIGLEC16 SIGLEC11	3.32e-05	5	64	2	21623346
Pubmed	Molecular analysis of human Siglec-8 orthologs relevant to mouse eosinophils: identification of mouse orthologs of Siglec-5 (mSiglec-F) and Siglec-10 (mSiglec-G).	SIGLEC16 SIGLEC11	4.98e-05	6	64	2	14559209
Pubmed	Cloning and characterization of human Siglec-11. A recently evolved signaling molecule that can interact with SHP-1 and SHP-2 and is expressed by tissue macrophages, including brain microglia.	SIGLEC16 SIGLEC11	4.98e-05	6	64	2	11986327
Pubmed	Are integrin alpha(2)beta(1), glycoprotein Ib and vWf levels correlated with their contributions to platelet adhesion on collagen under high-shear flow?	VWF COL1A1	4.98e-05	6	64	2	20063990
Pubmed	Identification of molecular determinants required for interaction of ubiquitin-conjugating enzymes and RING finger proteins.	UBE2L6 RNF144A	4.98e-05	6	64	2	11722579
Pubmed	Nidogen-2: a new basement membrane protein with diverse binding properties.	HSPG2 COL1A1	4.98e-05	6	64	2	9733643
Pubmed	Inhibition of Hb Binding to GP1bα Abrogates Hb-Mediated Thrombus Formation on Immobilized VWF and Collagen under Physiological Shear Stress.	VWF COL1A1	4.98e-05	6	64	2	27105433
Pubmed	Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.	SUCLG1 ALDOA ALDOB ALDOC	5.98e-05	114	64	4	28245920
Pubmed	A role for hedgehog signaling in the differentiation of the insertion site of the patellar tendon in the mouse.	GLI1 COL1A1	6.96e-05	7	64	2	23762363
Pubmed	von Willebrand factor binding to platelet GpIb initiates signals for platelet activation.	VWF COL1A1	6.96e-05	7	64	2	1939645
Pubmed	Paired Siglec receptors generate opposite inflammatory responses to a human-specific pathogen.	SIGLEC16 SIGLEC11	6.96e-05	7	64	2	28100677
Pubmed	Filamin B mutations cause chondrocyte defects in skeletal development.	FLNA COL1A1	9.27e-05	8	64	2	17510210
Pubmed	The leucine-rich repeat protein PRELP binds perlecan and collagens and may function as a basement membrane anchor.	HSPG2 COL1A1	9.27e-05	8	64	2	11847210
Pubmed	Periostin advances atherosclerotic and rheumatic cardiac valve degeneration by inducing angiogenesis and MMP production in humans and rodents.	VWF COL1A1	9.27e-05	8	64	2	20551517
Pubmed	3D Mapping Reveals a Complex and Transient Interstitial Matrix During Murine Kidney Development.	HSPG2 COL1A1	9.27e-05	8	64	2	33875569
Pubmed	Mapping Extracellular Protein-Protein Interactions Using Extracellular Proximity Labeling (ePL).	KRT1 FLNA EDC3 ABI3BP COL1A1	9.40e-05	247	64	5	39238192
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	TGM4 HSPG2 FLNA VWF SYPL1 SLC44A4 ALDOA ALDOC VASP	9.75e-05	1016	64	9	19056867
Pubmed	Widespread macromolecular interaction perturbations in human genetic disorders.	KRT1 FLNA GLI1 FSD2 ALDOA ALDOC ZNF496	1.05e-04	590	64	7	25910212
Pubmed	Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.	KRT1 HSPG2 COL1A1	1.10e-04	50	64	3	23658023
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	HSPG2 VWF ABI3BP COL1A1	1.15e-04	135	64	4	28675934
Pubmed	Perlecan is essential for cartilage and cephalic development.	HSPG2 COL1A1	1.19e-04	9	64	2	10545953
Pubmed	A large pool of actively cycling progenitors orchestrates self-renewal and injury repair of an ectodermal appendage.	GLI1 COL1A1	1.19e-04	9	64	2	31481792
Pubmed	Single nucleotide polymorphisms associated with aggressive periodontitis and severe chronic periodontitis in Japanese.	HSPG2 COL1A1	1.19e-04	9	64	2	15081423
Pubmed	Induction of Siglec-G by RNA viruses inhibits the innate immune response by promoting RIG-I degradation.	SIGLEC16 SIGLEC11	1.19e-04	9	64	2	23374343
Pubmed	Impaired skin and hair follicle development in Runx2 deficient mice.	KRT1 GLI1	1.19e-04	9	64	2	18262513
Pubmed	A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis.	GLI1 ALDOA ALDOC	1.30e-04	53	64	3	38466355
Pubmed	Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens.	DOCK11 NHLRC2 ALDOC VASP	1.44e-04	143	64	4	30397336
Pubmed	Epicardially derived fibroblasts preferentially contribute to the parietal leaflets of the atrioventricular valves in the murine heart.	FLNA COL1A1	1.49e-04	10	64	2	22546693
Pubmed	Essential role for Sonic hedgehog during hair follicle morphogenesis.	KRT1 GLI1	1.49e-04	10	64	2	9882493
Pubmed	Development of migrating tendon-bone attachments involves replacement of progenitor populations.	GLI1 COL1A1	1.49e-04	10	64	2	30504126
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	HSPG2 VWF ABI3BP COL1A1	1.56e-04	146	64	4	27068509
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	AFMID TGM4 USP34 FLNA EDC3 GLI1 DDX52 LMTK2 ZNF496	1.59e-04	1084	64	9	11544199
Pubmed	Extracellular matrix protein composition dynamically changes during murine forelimb development.	HSPG2 COL1A1	1.81e-04	11	64	2	38303699
Pubmed	Role of Indian hedgehog signaling in palatal osteogenesis.	GLI1 COL1A1	1.81e-04	11	64	2	21364421
Pubmed	SPARC, a secreted protein associated with cellular proliferation, inhibits cell spreading in vitro and exhibits Ca+2-dependent binding to the extracellular matrix.	HSPG2 COL1A1	1.81e-04	11	64	2	2745554
Pubmed	Gli1 protein participates in Hedgehog-mediated specification of osteoblast lineage during endochondral ossification.	GLI1 COL1A1	1.81e-04	11	64	2	22493482
Pubmed	Mitochondrial Raf1 Regulates Glutamine Catabolism.	RANBP10 ZNF618 ABCD1 SUCLG1 UAP1L1	1.92e-04	288	64	5	38496616
Pubmed	Identification of atrogin-1-targeted proteins during the myostatin-induced skeletal muscle wasting.	KRT1 ALDOA ALDOC COL1A1	1.96e-04	155	64	4	22673621
Pubmed	Role of GSK-3β in the osteogenic differentiation of palatal mesenchyme.	GLI1 COL1A1	2.17e-04	12	64	2	22022457
Pubmed	Kindlin-2 Is Essential for Preserving Integrity of the Developing Heart and Preventing Ventricular Rupture.	HSPG2 COL1A1	2.17e-04	12	64	2	30883226
Pubmed	Hedgehog signaling orchestrates cartilage-to-bone transition independently of Smoothened.	GLI1 COL1A1	2.17e-04	12	64	2	35472633
Pubmed	A novel modifier gene for plasma von Willebrand factor level maps to distal mouse chromosome 11.	VWF COL1A1	2.17e-04	12	64	2	8986815
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	HSPG2 FREM3 COL1A1	2.29e-04	64	64	3	22261194
Pubmed	Hypomorphic and dominant-negative impact of truncated SOX9 dysregulates Hedgehog-Wnt signaling, causing campomelia.	GLI1 COL1A1	2.57e-04	13	64	2	36584300
Pubmed	CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder.	SIGLEC16 SIGLEC11	2.57e-04	13	64	2	35921817
Pubmed	Gorab Is Required for Dermal Condensate Cells to Respond to Hedgehog Signals during Hair Follicle Morphogenesis.	KRT1 GLI1	2.57e-04	13	64	2	26967474
Pubmed	Role of epidermal primary cilia in the homeostasis of skin and hair follicles.	KRT1 GLI1	2.57e-04	13	64	2	21429982
Pubmed	Noggin Overexpression Impairs the Development of Muscles, Tendons, and Aponeurosis in Soft Palates by Disrupting BMP-Smad and Shh-Gli1 Signaling.	GLI1 COL1A1	2.57e-04	13	64	2	34557486
Pubmed	NFAT5/TonEBP controls early acquisition of notochord phenotypic markers, collagen composition, and sonic hedgehog signaling during mouse intervertebral disc embryogenesis.	GLI1 COL1A1	2.57e-04	13	64	2	31301300
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	HSPG2 VWF ABI3BP COL1A1	2.60e-04	167	64	4	22159717
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	AFMID RANBP10 SYPL1 FSD2 PKHD1L1 TARBP1 ALPK2	2.64e-04	686	64	7	29987050
Pubmed	mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.	KRT1 FLNA ALDOA UAP1L1 VASP	2.78e-04	312	64	5	37120454
Pubmed	Membrane-type MMPs are indispensable for placental labyrinth formation and development.	HSPG2 COL1A1	2.99e-04	14	64	2	20858856
Pubmed	Desert hedgehog-primary cilia cross talk shapes mitral valve tissue by organizing smooth muscle actin.	FLNA COL1A1	2.99e-04	14	64	2	32151560
Pubmed	The transcription factor Foxc1 is necessary for Ihh-Gli2-regulated endochondral ossification.	GLI1 COL1A1	2.99e-04	14	64	2	25808752
Pubmed	Role of LTBP4 in alveolarization, angiogenesis, and fibrosis in lungs.	VWF COL1A1	3.45e-04	15	64	2	28684544
Pubmed	Fgfr2 is integral for bladder mesenchyme patterning and function.	GLI1 COL1A1	3.45e-04	15	64	2	28052872
Pubmed	WNT signals are required for the initiation of hair follicle development.	KRT1 GLI1	3.45e-04	15	64	2	12015971
Pubmed	Tsukushi controls the hair cycle by regulating TGF-β1 signaling.	KRT1 GLI1	3.45e-04	15	64	2	22995554
Pubmed	The steroid and xenobiotic receptor negatively regulates B-1 cell development in the fetal liver.	SIGLEC16 SIGLEC11	3.45e-04	15	64	2	22496360
Cytoband	10q25.3	AFAP1L2 NHLRC2	7.58e-04	29	64	2	10q25.3
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	HSPG2 SIGLEC16 SIGLEC11 ALPK2	5.70e-04	161	43	4	593
GeneFamily	CD molecules\|C2-set domain containing\|Sialic acid binding Ig like lectins	SIGLEC16 SIGLEC11	2.01e-03	28	43	2	745
GeneFamily	C2-set domain containing\|Immunoglobulin like domain containing\|Scavenger receptors	SIGLEC16 SIGLEC11	4.07e-03	40	43	2	592
GeneFamily	DEAD-box helicases	DDX52 DDX56	4.48e-03	42	43	2	499
GeneFamily	Adenosine receptors\|V-set domain containing	BTNL8 SIGLEC16 SIGLEC11	6.82e-03	163	43	3	590
Coexpression	GSE7459_UNTREATED_VS_IL6_TREATED_ACT_CD4_TCELL_UP	RANBP10 ABI3BP DDX52 SNAPC4 MORC4 ALPK2	1.11e-06	138	64	6	M462
Coexpression	MOOTHA_GLYCOLYSIS	ALDOA ALDOB ALDOC	1.79e-05	21	64	3	M16111
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLNA ABI3BP HECTD2 GLI1 DIXDC1 COL1A1	2.83e-07	186	64	6	6add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FLNA ABI3BP HECTD2 GLI1 DIXDC1 COL1A1	4.20e-07	199	64	6	e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FLNA ABI3BP HECTD2 GLI1 DIXDC1 COL1A1	4.33e-07	200	64	6	c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FLNA ABI3BP HECTD2 GLI1 DIXDC1 COL1A1	4.33e-07	200	64	6	08bf8c00eee6468215edb3611296bfc8784c4d56
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FLNA ABI3BP HECTD2 GLI1 DIXDC1 COL1A1	4.33e-07	200	64	6	dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCell	343B-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SLC6A4 VWF BTNL8 AFF3 LMTK2	7.16e-06	186	64	5	dae6a98963c78bf7518ebab8dc02f173c3b0f7f7
ToppCell	343B-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SLC6A4 VWF BTNL8 AFF3 LMTK2	7.16e-06	186	64	5	080e56113b89138277a2bd2eabddfa6cd1a18b61
ToppCell	P15-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	VWF ABI3BP RNF144A ALDOA ALDOC	7.54e-06	188	64	5	50b27fc12347ca16bd62333baf345c83cb422a8f
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABI3BP HECTD2 GLI1 DIXDC1 COL1A1	7.54e-06	188	64	5	293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 IQSEC3 VWF ABI3BP PKHD1L1	7.54e-06	188	64	5	26915db8863f4115b46a81982e187322e21600fd
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 IQSEC3 VWF ABI3BP PKHD1L1	7.54e-06	188	64	5	3f76c0f912f8f023ea425be7f43593b3d7f967e3
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 IQSEC3 VWF ABI3BP PKHD1L1	7.54e-06	188	64	5	61ee7b152745164293d8a44ef91ee2393efbdca5
ToppCell	343B-Endothelial_cells-Endothelial-B_(Artery)\|343B / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 AFAP1L2 VWF ABI3BP DIXDC1	8.14e-06	191	64	5	27a532a35d9e8822014f581fd56c4ca62e39f8fe
ToppCell	Control-Endothelial-VE_Venous\|Control / Disease state, Lineage and Cell class	SLC6A4 HSPG2 VWF ABI3BP PKHD1L1	8.14e-06	191	64	5	617546cf4883dedf3323e03a53ba5adec334cf8e
ToppCell	343B-Endothelial_cells-Endothelial-B_(Artery)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 AFAP1L2 VWF ABI3BP DIXDC1	8.14e-06	191	64	5	1dfcff08e01e6a695953334342bcfde04ba005ad
ToppCell	droplet-Pancreas-Exocrine-21m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA AFAP1L2 ABI3BP RNF144A COL1A1	8.78e-06	194	64	5	775600880bb77781de48085d8744c1030223de1f
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 DIXDC1 SLC44A4 FAM135B ALPK2	8.78e-06	194	64	5	70185c0b8e0f4e896645b17a243482ba3cdf4a5d
ToppCell	droplet-Pancreas-Exocrine-21m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA AFAP1L2 ABI3BP RNF144A COL1A1	8.78e-06	194	64	5	04ecb609d233a4b12e275c604810937830363e17
ToppCell	COVID-19-lung-Capillary_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC6A4 VWF BTNL8 RNF144A AFF3	9.23e-06	196	64	5	ac28e9be288af6f00a841aea4ce4b99aed6b4505
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC6A4 HSPG2 VWF ABI3BP PKHD1L1	9.46e-06	197	64	5	8437c33e2c4a10a1b95343431e48d5e820b1f742
ToppCell	COVID-19-lung-Capillary_1\|lung / Disease (COVID-19 only), tissue and cell type	SLC6A4 VWF BTNL8 RNF144A AFF3	9.46e-06	197	64	5	7e86ff9dafcbaaa7464d61484dd48bfeb7eae6e4
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC6A4 HSPG2 VWF ABI3BP PKHD1L1	9.46e-06	197	64	5	0542badae77d2f606c13cfaf361319495c354351
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC6A4 HSPG2 VWF ABI3BP PKHD1L1	9.46e-06	197	64	5	a6a64581699cfcb9607b288976fa3b09648725b7
ToppCell	normal_Lung-Endothelial_cells-Stalk-like_ECs\|normal_Lung / Location, Cell class and cell subclass	HSPG2 AFAP1L2 VWF ABI3BP DIXDC1	9.69e-06	198	64	5	2a251d13c2488d15ca9b11e643c1d17d428b6ef0
ToppCell	distal-Endothelial-Vein-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SLC6A4 HSPG2 VWF ABI3BP PKHD1L1	9.93e-06	199	64	5	f9fc0482d7ab11f2165b30cce3564b4ff87d61a6
ToppCell	cellseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SLC6A4 HSPG2 VWF ABI3BP PKHD1L1	9.93e-06	199	64	5	68412bc39639edc4045437d62548f7101b9f1989
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	FLNA ABI3BP GLI1 DIXDC1 COL1A1	1.02e-05	200	64	5	c5e051f1aac8dda376c342a9932785a23450e073
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FLNA DOCK11 DIXDC1 ALDOC COL1A1	1.02e-05	200	64	5	a3a1e35934d676c39f917652e50c502cb2f613c1
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	FLNA ABI3BP GLI1 DIXDC1 COL1A1	1.02e-05	200	64	5	9d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FLNA ABI3BP HECTD2 DIXDC1 COL1A1	1.02e-05	200	64	5	87827041663013f5e7273168dc8709d69840e7ce
ToppCell	distal-3-Endothelial-Vein\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SLC6A4 HSPG2 VWF ABI3BP PKHD1L1	1.02e-05	200	64	5	3a5c85bad2e7a9ecf55d90acb04178a343b3f5fd
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FLNA DOCK11 DIXDC1 ALDOC COL1A1	1.02e-05	200	64	5	c06426f877919bdd267ea2fd7e7973c6619832ae
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	FLNA ABI3BP HECTD2 DIXDC1 COL1A1	1.02e-05	200	64	5	593bf6a7c557437db9a9249a5058a46014179ef6
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FLNA ABI3BP HECTD2 DIXDC1 COL1A1	1.02e-05	200	64	5	8988f113708eef7d9d2a6a6c1bcfd7c8f9804d3e
ToppCell	normal_Lung-Endothelial_cells-Stalk-like_ECs\|Endothelial_cells / Location, Cell class and cell subclass	HSPG2 AFAP1L2 VWF ABI3BP DIXDC1	1.02e-05	200	64	5	413ac64bbe95b8c921c5396d8b5f298fec8c4f82
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic\|LPS_only / Treatment groups by lineage, cell group, cell type	FLNA ABI3BP HECTD2 DIXDC1 COL1A1	1.02e-05	200	64	5	02cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCell	distal-Endothelial-Vein\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SLC6A4 HSPG2 VWF ABI3BP PKHD1L1	1.02e-05	200	64	5	6acf7afe122f81a95c4c66f4d0878d997b57127a
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	AFMID IQSEC3 ZNF74 FSD2	5.81e-05	146	64	4	1bf67a9416f52198931b912a31be4bab09fefd19
ToppCell	Bac-SEP-Lymphocyte-T_NK-dnT\|Bac-SEP / Disease, Lineage and Cell Type	ZNF717 SEPHS2 AFAP1L2 ALDOC	8.29e-05	160	64	4	f5ca49801c981b903a85a64b21ece6b59fe91cbc
ToppCell	NS-critical-LOC-Myeloid-Basophil\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	IQSEC3 CTPS2 ZNF618 RNF144A	8.29e-05	160	64	4	8a4746463ca1976f7d6de803496c851249ced797
ToppCell	Adult-Endothelial-endothelial_cell_of_vein-D122\|Adult / Lineage, Cell type, age group and donor	SLC6A4 AFAP1L2 VWF PKHD1L1	8.29e-05	160	64	4	0cfe130606af433b2aa90e0a20b6c44659dd6fd4
ToppCell	Club-club-13\|World / Class top	ATP13A5 BPIFA1 SLC44A4 COL1A1	8.70e-05	162	64	4	7d18f05a65ac715e62d610df9cc4a26539340dee
ToppCell	Club-club-12\|World / Class top	ATP13A5 BPIFA1 SLC44A4 ALDOC	9.34e-05	165	64	4	9b7a31cbdcd2f96b8bd08a4cd4141b92bd5e9062
ToppCell	Mild-Myeloid-Mast\|Mild / Condition, Lineage, Cell class and cell subclass	HSPG2 VWF RNF144A FAM135B	9.34e-05	165	64	4	5fa9552c37890c5cc7e672a47038aebba2413cb4
ToppCell	Mild-Myeloid-Mast-\|Mild / Condition, Lineage, Cell class and cell subclass	HSPG2 VWF RNF144A FAM135B	9.34e-05	165	64	4	93d3909a0f5f43d473d5005c842d7d73e25eceed
ToppCell	Adult-Mesenchymal-myofibroblast_cell\|Adult / Lineage, Cell type, age group and donor	AFAP1L2 ABI3BP GLI1 COL1A1	9.78e-05	167	64	4	d584a8548a5317bd9686b3be8246ae6ed568796b
ToppCell	356C-Endothelial_cells-Endothelial-B_(Artery)\|356C / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 AFAP1L2 VWF ABI3BP	1.02e-04	169	64	4	605cc2638271803cf1d972ab3fa8f13f89666376
ToppCell	356C-Endothelial_cells-Endothelial-B_(Artery)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 AFAP1L2 VWF ABI3BP	1.02e-04	169	64	4	337be3bf485b54afad86e256cb0c4c1d0c2a9a2a
ToppCell	facs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT1 AFAP1L2 HECTD2 DIXDC1	1.07e-04	171	64	4	b54d9d6b03c9c6f28a71cf2ed2bfa9a335bba949
ToppCell	facs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT1 AFAP1L2 HECTD2 DIXDC1	1.07e-04	171	64	4	9d825a2e799421af4f2cf4f4dc8e239b5d00476d
ToppCell	ICU-SEP-Lymphocyte-B-B_intermediate\|ICU-SEP / Disease, Lineage and Cell Type	HLA-DOA AFF3 SYPL1 PKHD1L1	1.07e-04	171	64	4	2e44bf6f3d90193e7cadcac48bb852bd632a81bc
ToppCell	Club-club-3\|World / Class top	BPIFA1 SLC44A4 ALDOC PKHD1L1	1.10e-04	172	64	4	34fbb82a2ec77dd183cf26b38edeb7e936b707bc
ToppCell	10x5'-Lung-Lymphocytic_B-Memory_B_cells\|Lung / Manually curated celltypes from each tissue	AFAP1L2 AFF3 ALDOB PKHD1L1	1.10e-04	172	64	4	2cb2dc7cfd6db5a98a393b1a84c23abf3d692a53
ToppCell	(6)_Endothelial_cells-(6)_Endothelial-E\|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	SLC6A4 VWF BTNL8 AFF3	1.15e-04	174	64	4	4a1b67ce5ea353b3f81f59fa57da07668146afca
ToppCell	CV-Healthy-4\|Healthy / Virus stimulation, Condition and Cluster	SYPL1 ALDOA UBASH3A ALDOC	1.15e-04	174	64	4	26544cc5f51cb4dc1251e62d9f80b6c956194d38
ToppCell	Adult-Endothelial-endothelial_cell_of_vein-D231\|Adult / Lineage, Cell type, age group and donor	HSPG2 VWF ABI3BP PKHD1L1	1.15e-04	174	64	4	2dd647c4fdf99fd1f7b838efef01baf2cbc3446d
ToppCell	(03)_Secretory\|World / shred by cell type and Timepoint	ATP13A5 BPIFA1 SLC44A4 ALDOC	1.20e-04	176	64	4	cb7b1945788196ca79007f0768b6576ec885a0e5
ToppCell	AT1_cells-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	SLC6A4 HSPG2 ABI3BP FREM3	1.20e-04	176	64	4	458720776b0151cd55acc352d509599cb62f0ca8
ToppCell	Adult-Endothelial-endothelial_cell_of_vein\|Adult / Lineage, Cell type, age group and donor	SLC6A4 VWF ABI3BP PKHD1L1	1.20e-04	176	64	4	043683c61c5d1a7f8a4666a612310246bd3d83a2
ToppCell	E16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC6A4 VWF UBASH3A ALDOB	1.22e-04	177	64	4	84591e28482ab62a5ef41e61043eb64912766356
ToppCell	E16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC6A4 VWF UBASH3A ALDOB	1.22e-04	177	64	4	4bc100062891d07cacd10ffba38966cc6302c92f
ToppCell	E16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC6A4 VWF UBASH3A ALDOB	1.22e-04	177	64	4	9f3a2adb9cd4f0a059afc87b6e377a9702154bb1
ToppCell	Hippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Nts_(Neuron.Slc17a6.Nts)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SLC44A4 TARBP1 ALPK2	1.23e-04	67	64	3	bc06a697f47b60c43e238f8c6803a1b061f22550
ToppCell	Hippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Nts_(Neuron.Slc17a6.Nts)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SLC44A4 TARBP1 ALPK2	1.23e-04	67	64	3	50acd69659f6d827868dc48bfb00af8634a8b4c7
ToppCell	Endothelial-A-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	SLC6A4 AFAP1L2 VWF ABI3BP	1.25e-04	178	64	4	2f2602b9305d55f25afa9861dd6c6347ae179337
ToppCell	droplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AFAP1L2 VWF BPIFA1 ALDOB	1.28e-04	179	64	4	a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCell	COPD-Endothelial-VE_Venous\|World / Disease state, Lineage and Cell class	SLC6A4 VWF ABI3BP PKHD1L1	1.28e-04	179	64	4	9968da1adcb561d9bf167a42ab5d9de85c071c4a
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IQSEC3 ABI3BP GLI1 COL1A1	1.28e-04	179	64	4	948c2a01ec7a626c68281e6e796a9f0527a88591
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEPHS2 GLI1 ZNF496 COL1A1	1.28e-04	179	64	4	ce3ca7f3a5864e62307aa744a3173f350a90df28
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_memory-B_memory-0\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HLA-DOA AFF3 SYPL1 PKHD1L1	1.28e-04	179	64	4	fce1ba53815145f6248d4e90aedca3dad84e33e4
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HSPG2 AFAP1L2 VWF ABI3BP	1.31e-04	180	64	4	40d4838a0ccb10d5e49266bc8a0037d27b75ccc2
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SLC6A4 HSPG2 VWF ABI3BP	1.31e-04	180	64	4	27e8bbee388e64dd79d70b160b76d45b1f398006
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(other)\|COVID-19 / group, cell type (main and fine annotations)	SLC6A4 VWF BTNL8 AFF3	1.33e-04	181	64	4	26eb4ee57a70dbf54e096b73129fda9dfda1f6ec
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AFAP1L2 VWF ABI3BP RNF144A	1.33e-04	181	64	4	4d7793026373cbcf04b15c77f95f1025d07d4c00
ToppCell	droplet-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 AFAP1L2 VWF PKHD1L1	1.33e-04	181	64	4	2c44c41b4e8a75ebdbaeb0c6cc5a03f17c44758c
ToppCell	TCGA-Colorectal-Solid_Tissue_Normal\|TCGA-Colorectal / Sample_Type by Project: Shred V9	ABI3BP AFF3 PKHD1L1 FAM135B	1.33e-04	181	64	4	88f6f56f5f58b479d5db91b32c45934c045f88ea
ToppCell	Int-URO-Lymphocyte-B-B_naive\|Int-URO / Disease, Lineage and Cell Type	HLA-DOA AFF3 SYPL1 PKHD1L1	1.36e-04	182	64	4	af7482c63e87a53cf686200a8f4d5b9749235dcd
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AFAP1L2 VWF ABI3BP RNF144A	1.39e-04	183	64	4	3427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 AFAP1L2 MORC4 ALDOB	1.39e-04	183	64	4	351d575339038bd4a66f408da518c567444208e8
ToppCell	facs-Liver-Non-hepatocytes-24m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT1 ABI3BP PKHD1L1 COL1A1	1.39e-04	183	64	4	ebe369dc80c4fbf8f4dbe947147f8c47507ffb60
ToppCell	3'_v3-bone_marrow-Lymphocytic_B-Memory_B_cells\|bone_marrow / Manually curated celltypes from each tissue	HLA-DOA AFF3 SYPL1 PKHD1L1	1.42e-04	184	64	4	ffc9eec123de34a4f17ed27fe4f0a1b3cb84697f
ToppCell	metastatic_Brain-Endothelial_cells-Stalk-like_ECs\|metastatic_Brain / Location, Cell class and cell subclass	HSPG2 VWF HECTD2 DIXDC1	1.45e-04	185	64	4	ad52970e88e8947ef256095bd4b40229b912d58a
ToppCell	droplet-Lung-nan-3m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AFAP1L2 VWF ABI3BP PKHD1L1	1.45e-04	185	64	4	eeb6f55a6f79adf80247baa2c4b0df44553557ad
ToppCell	Endothelial-A-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	HSPG2 AFAP1L2 VWF ABI3BP	1.45e-04	185	64	4	ae49c61f6ecf128fe2a958b8c75c83688da75f59
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_memory-B_memory-3\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HLA-DOA AFF3 SYPL1 PKHD1L1	1.45e-04	185	64	4	05e6eb78ead81268c1656e7ffe34f9cb7329b908
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABI3BP HECTD2 DIXDC1 COL1A1	1.45e-04	185	64	4	e64e8c98dd88d91f6501d3fb10b60fd2f3c90af3
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HSPG2 AFAP1L2 VWF ABI3BP	1.45e-04	185	64	4	a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCell	URO-Lymphocyte-B\|URO / Disease, Lineage and Cell Type	HLA-DOA AFF3 SYPL1 PKHD1L1	1.48e-04	186	64	4	c46ff4fc280b67a454ee9614e93c6854a5a400b8
ToppCell	BLOOD--(2)_Naive_B_cells\| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	HLA-DOA AFF3 SYPL1 PKHD1L1	1.48e-04	186	64	4	2e55a3892459152fc4a3a7834ccbf5d71b65d29a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 SLC44A4 FAM135B ALPK2	1.48e-04	186	64	4	f28d72b47624b69a580b4429e2be560a26898591
ToppCell	BLOOD--(2)_B_cell\| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	HLA-DOA AFF3 SYPL1 PKHD1L1	1.48e-04	186	64	4	d9f2cab7f9e7aa476d9bcf5d15896113e59e03f8
ToppCell	ILEUM-inflamed-(8)_Fibroblast-(8)_Smooth_muscle_cells\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ABI3BP GLI1 AFF3 UBASH3A	1.48e-04	186	64	4	cacc2f0b2ed46516173b61ba1c5c226a2db7cddc
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_memory\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	HLA-DOA AFF3 SYPL1 PKHD1L1	1.51e-04	187	64	4	ea56cfca919a09db852b7ee5e42323f822962465
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SLC6A4 HSPG2 VWF ABI3BP	1.51e-04	187	64	4	e35716f8b482be3bf5ab79f087a9caf67a9d197a
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AFAP1L2 VWF ABI3BP PKHD1L1	1.51e-04	187	64	4	12129e02638c20d9b7c1c6e512d48bfd966e1029
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	AFMID DIXDC1 ALDOB ALPK2	1.51e-04	187	64	4	dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABI3BP GLI1 PKHD1L1 COL1A1	1.51e-04	187	64	4	4e553721fa5598cb211f44e3226280b7e6885484
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_memory-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	HLA-DOA AFF3 SYPL1 PKHD1L1	1.51e-04	187	64	4	43f81863063509337bd56a67010c62fb51109bd5
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABI3BP GLI1 PKHD1L1 COL1A1	1.51e-04	187	64	4	d36e7fc6125e7a4310499365022d38f34b757a73
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABI3BP GLI1 PKHD1L1 COL1A1	1.51e-04	187	64	4	827eae63fabf6892a82ce7779b5f395958d3d628
Computational	Glycolysis and TCA cycle.	SUCLG1 ALDOA ALDOC	9.24e-05	26	37	3	MODULE_306
Drug	2-keto-3-deoxy- l-lyxonate	ALDOA ALDOB ALDOC	2.12e-08	3	64	3	CID000192781
Drug	acetol phosphate	ALDOA ALDOB ALDOC	2.12e-08	3	64	3	CID000150865
Drug	androisoxazole	ALDOA ALDOB ALDOC	2.12e-08	3	64	3	CID000009676
Drug	2-keto-3-bromobutyrate	ALDOA ALDOB ALDOC	2.12e-08	3	64	3	CID000191968
Drug	3-isochromanone	ALDOA ALDOB ALDOC	2.12e-08	3	64	3	CID000078092
Drug	5-deoxy-5-fluoro-L-sorbose	ALDOA ALDOB ALDOC	2.12e-08	3	64	3	CID000191809
Drug	D-ribulose-1-p	ALDOA ALDOB ALDOC	2.12e-08	3	64	3	CID000000615
Drug	4-hydroxy-9-fluorenone	ALDOA ALDOB ALDOC	2.12e-08	3	64	3	CID000016139
Drug	4-hydroxy-2-ketopimelate	ALDOA ALDOB ALDOC	2.12e-08	3	64	3	CID000000553
Drug	AC1L19F1	ALDOA ALDOB ALDOC	2.12e-08	3	64	3	CID000000519
Drug	Htfp	ALDOA ALDOB ALDOC	2.12e-08	3	64	3	CID000125055
Drug	DIDIT	ALDOA ALDOB ALDOC	2.12e-08	3	64	3	CID000196082
Drug	C06441	ALDOA ALDOB ALDOC	8.46e-08	4	64	3	CID000441020
Drug	formylacetate	ALDOA ALDOB ALDOC	8.46e-08	4	64	3	CID000075269
Drug	3-hydroxy-1-indanone	ALDOA ALDOB ALDOC	8.46e-08	4	64	3	CID000176448
Drug	l-123	ALDOA ALDOB ALDOC	8.46e-08	4	64	3	CID000093552
Drug	dihydroxyacetone sulfate	ALDOA ALDOB ALDOC	8.46e-08	4	64	3	CID000439751
Drug	1,3-dioxan-5-one	ALDOA ALDOB ALDOC	2.11e-07	5	64	3	CID009793707
Drug	AC1L4F2K	ALDOA ALDOB ALDOC	2.11e-07	5	64	3	CID000184526
Drug	gamma-oxalocitramalate	ALDOA ALDOB ALDOC	2.11e-07	5	64	3	CID000000130
Drug	phosphoglycollamide	ALDOA ALDOB ALDOC	2.11e-07	5	64	3	CID000191768
Drug	D-erythrulose 1-phosphate	ALDOA ALDOB ALDOC	2.11e-07	5	64	3	CID000152153
Drug	2,3-dihydroxy-p-cumate	ALDOA ALDOB ALDOC	2.11e-07	5	64	3	CID000029587
Drug	AC1NX490	ALDOA ALDOB ALDOC	2.11e-07	5	64	3	CID005743230
Drug	hydroxypyruvaldehyde phosphate	ALDOA ALDOB ALDOC	2.11e-07	5	64	3	CID000193787
Drug	mycestericin D	ALDOA ALDOB ALDOC	4.21e-07	6	64	3	CID006439504
Drug	2,2-dimethyl-1,3-dioxan-5-one	ALDOA ALDOB ALDOC	4.21e-07	6	64	3	CID002733141
Drug	2-(N-decyl)aminonaphthalene-6-sulfonic acid	ALDOA ALDOB ALDOC	4.21e-07	6	64	3	CID000189836
Drug	parapyruvate	ALDOA ALDOB ALDOC	4.21e-07	6	64	3	CID000440249
Drug	acetyldithio-CoA	ALDOA ALDOB ALDOC	4.21e-07	6	64	3	CID003082679
Drug	0 Gz	ALDOA ALDOB ALDOC	4.21e-07	6	64	3	CID000000372
Drug	chloroacetol phosphate	ALDOA ALDOB ALDOC	4.21e-07	6	64	3	CID000168137
Drug	C02783	ALDOA ALDOB ALDOC	4.21e-07	6	64	3	CID000439805
Drug	5-deoxy-D-xylulose-1-phosphate	ALDOA ALDOB ALDOC	7.35e-07	7	64	3	CID000192931
Drug	Z-Glu-Tyr	ALDOA ALDOB ALDOC	7.35e-07	7	64	3	CID000096820
Drug	acenaphthenone	ALDOA ALDOB ALDOC	7.35e-07	7	64	3	CID000075229
Drug	C0447	ALDOA ALDOB ALDOC	7.35e-07	7	64	3	CID000128786
Drug	DAPpNP	ALDOA ALDOB ALDOC	7.35e-07	7	64	3	CID005492375
Drug	AC1L2T2K	FLNA ALDOA ALDOB ALDOC	8.10e-07	26	64	4	CID000128038
Drug	AC1Q6S3P	DDX52 DDX56 ALDOA ALDOB ALDOC	9.28e-07	63	64	5	CID000000665
Drug	3-hydroxy-4-oxobutyl-1-phosphonate	ALDOA ALDOB ALDOC	1.17e-06	8	64	3	CID003016813
Drug	L-rhamnulose-1-phosphate	ALDOA ALDOB ALDOC	1.17e-06	8	64	3	CID000439413
Drug	amorphin	ALDOA ALDOB ALDOC	1.17e-06	8	64	3	CID000122792
Drug	2-oxopentenoate	ALDOA ALDOB ALDOC	1.76e-06	9	64	3	CID000000976
Drug	AC1Q5BXE	HSPG2 ALDOA ALDOB ALDOC	1.92e-06	32	64	4	CID000000037
Drug	lactaldehyde	ABCD1 ALDOA ALDOB ALDOC	1.92e-06	32	64	4	CID000000855
Drug	7,8-dihydro-D-neopterin	DDX52 DDX56 ALDOA ALDOB ALDOC	2.37e-06	76	64	5	CID000000659
Drug	3,4-dihydro-2(1H)-quinolinone	SLC6A4 ALDOA ALDOC	2.51e-06	10	64	3	CID000064796
Drug	tartronate semialdehyde	ALDOA ALDOB ALDOC	2.51e-06	10	64	3	CID000001122
Drug	SM-8	ALDOA ALDOB ALDOC	2.51e-06	10	64	3	CID000486037
Drug	1trd	ALDOA ALDOB ALDOC	4.58e-06	12	64	3	CID000004797
Drug	dihydropteridine	ALDOA ALDOB ALDOC	4.58e-06	12	64	3	CID000000167
Drug	ManNAc-6-P	ALDOA ALDOB ALDOC UAP1L1	5.86e-06	42	64	4	CID000000898
Drug	fuculose	ALDOA ALDOB ALDOC	5.94e-06	13	64	3	CID000000841
Drug	beta-isopropyl-tropolone	ALDOA ALDOB ALDOC	7.54e-06	14	64	3	CID000080297
Drug	2-keto-4-hydroxyglutarate	ALDOA ALDOB ALDOC	7.54e-06	14	64	3	CID000000599
Drug	Ichiba acid	ALDOA ALDOC	7.78e-06	2	64	2	CID000440403
Drug	3-HM	ALDOA ALDOC	7.78e-06	2	64	2	CID000439464
Drug	bromohydroxyacetone phosphate	ALDOA ALDOC	7.78e-06	2	64	2	CID000152675
Drug	anthracene diol	ALDOA ALDOC	7.78e-06	2	64	2	CID000155464
Drug	glyoxylate	PEX6 ABCD1 SUCLG1 ALDOA ALDOB ALDOC	1.01e-05	176	64	6	CID000000760
Drug	glycidaldehyde	ALDOA ALDOB ALDOC	1.16e-05	16	64	3	CID000013002
Drug	3-bromopyruvate	HSPG2 ALDOA ALDOB ALDOC	1.39e-05	52	64	4	CID000070684
Drug	ZnATP	ALDOA ALDOB ALDOC	1.40e-05	17	64	3	CID006455240
Drug	trimethylaminobutyraldehyde	ALDOA ALDOB ALDOC	1.40e-05	17	64	3	CID000000133
Drug	N-bromoacetylethanolamine phosphate	ALDOA ALDOB ALDOC	1.40e-05	17	64	3	CID000188343
Drug	3HPP	ALDOA ALDOB ALDOC	1.40e-05	17	64	3	CID000000091
Drug	gluconate	AFF3 ABCD1 SUCLG1 ALDOA ALDOB ALDOC COL1A1	1.58e-05	287	64	7	CID000000604
Drug	1H-imidazole hydrochloride	ALDOA ALDOB ALDOC	1.68e-05	18	64	3	CID000518985
Drug	2-deoxyribose 5-phosphate	ALDOA ALDOB ALDOC	1.68e-05	18	64	3	CID000150629
Drug	PF-00539745-00 [351321-33-0]; Down 200; 10uM; PC3; HT_HG-U133A	TGM4 LMTK2 PEX6 ZNF74 FAAP100 KIF1C	1.92e-05	197	64	6	5939_DN
Drug	AC1L2YVP	ALDOA ALDOB ALDOC	1.99e-05	19	64	3	CID000080135
Drug	malonate semialdehyde	ALDOA ALDOB ALDOC	1.99e-05	19	64	3	CID000000868
Drug	4-fluorothreonine	ALDOA ALDOC	2.33e-05	3	64	2	CID000128057
Drug	(4S,7R,8R,9R,13Z,16S)-4,8-dihydroxy-5,5,7,9-tetramethyl-16-[(E)-1-methyl-2-(2-methylthiazol-4-yl)vinyl]-1-oxacyclohexadec-13-ene-2,6-dione	ALDOA ALDOC	2.33e-05	3	64	2	CID009869661
Drug	3,3,3-trifluoropropanoic acid	ALDOA ALDOC	2.33e-05	3	64	2	CID002777972
Drug	AC1L19ID	ALDOA ALDOC	2.33e-05	3	64	2	CID000000560
Drug	C11 -427	ALDOA ALDOC	2.33e-05	3	64	2	CID000443195
Drug	AC1Q6S6V	ALDOA ALDOB ALDOC	2.33e-05	20	64	3	CID000000475
Drug	acetyltryptophanamide	AFMID ALDOA ALDOC	2.72e-05	21	64	3	CID000002003
Drug	d-sedoheptulose 1,7-diphosphate	ALDOA ALDOB ALDOC	3.14e-05	22	64	3	CID000001193
Drug	diphenylacetylene	ALDOA ALDOB ALDOC	3.14e-05	22	64	3	CID000010390
Drug	2-carboxybenzaldehyde	ALDOA ALDOB ALDOC	3.60e-05	23	64	3	CID000008406
Drug	h Kp	ALDOA ALDOB ALDOC	3.60e-05	23	64	3	CID000000124
Drug	9-fluorenone-1-carboxylic acid	ALDOA ALDOC	4.65e-05	4	64	2	CID000074083
Drug	phenanthrene trans-3,4-dihydrodiol	ALDOA ALDOC	4.65e-05	4	64	2	CID000119398
Drug	DHMP	ALDOA ALDOC	4.65e-05	4	64	2	CID000098784
Drug	AC1L9A8P	ALDOA ALDOC	4.65e-05	4	64	2	CID000440943
Drug	deoxyribose	ALDOA ALDOB ALDOC	4.66e-05	25	64	3	CID000010786
Drug	mpMap	ALDOA ALDOB ALDOC	4.66e-05	25	64	3	CID000100806
Drug	pteridine	AFMID ALDOA ALDOB ALDOC	4.79e-05	71	64	4	CID000001043
Drug	oxalocrotonate	ALDOA ALDOB ALDOC	5.26e-05	26	64	3	CID000440019
Drug	AC1MRI6N	ALDOA ALDOB ALDOC	5.90e-05	27	64	3	CID000417447
Drug	1H-n	ALDOA ALDOB ALDOC	5.90e-05	27	64	3	CID000006844
Drug	neuraminic acid	ALDOA ALDOB ALDOC ALPK2	6.26e-05	76	64	4	CID000441037
Drug	diketone	ALDOA ALDOB ALDOC	6.60e-05	28	64	3	CID000167775
Drug	dihydroxyacetone phosphate	PEX6 ABCD1 ALDOA ALDOB ALDOC	7.11e-05	153	64	5	CID000000668
Drug	1-o-phosphonohex-2-ulose	ALDOA ALDOB ALDOC	7.35e-05	29	64	3	CID000000481
Drug	alpha-methylserine	ALDOA ALDOC	7.74e-05	5	64	2	CID000094309
Drug	f-3p	ALDOA ALDOC	7.74e-05	5	64	2	CID015991581
Disease	liver benign neoplasm (biomarker_via_orthology)	ALDOB COL1A1	2.36e-04	11	62	2	DOID:916 (biomarker_via_orthology)
Disease	Schwartz-Jampel Syndrome, Type 1	HSPG2 FLNA	5.11e-04	16	62	2	C4551479
Disease	Spondyloepiphyseal Dysplasia	HSPG2 FLNA	5.11e-04	16	62	2	C0038015
Disease	Schwartz-Jampel Syndrome	HSPG2 FLNA	5.11e-04	16	62	2	C0036391
Disease	Melnick-Needles Syndrome	HSPG2 FLNA	5.11e-04	16	62	2	C0025237
Disease	Spondyloepiphyseal Dysplasia Tarda, X-Linked	HSPG2 FLNA	5.11e-04	16	62	2	C3541456
Disease	lung carcinoma	RIF1 HLA-DOA ZNF618 SIGLEC11 SLC44A4 UBASH3A	5.22e-04	482	62	6	EFO_0001071
Disease	Disproportionate short stature	HSPG2 FLNA COL1A1	5.78e-04	77	62	3	C0878659
Disease	Van Buchem disease	HSPG2 FLNA	5.79e-04	17	62	2	C0432272
Disease	borna disease (biomarker_via_orthology)	SLC6A4 ALDOC	6.50e-04	18	62	2	DOID:5154 (biomarker_via_orthology)
Disease	carotid artery disease (is_marker_for)	HSPG2 VWF	7.26e-04	19	62	2	DOID:3407 (is_marker_for)
Disease	osteochondrodysplasia (is_implicated_in)	HSPG2 FLNA	7.26e-04	19	62	2	DOID:2256 (is_implicated_in)
Disease	Dyschondroplasias	HSPG2 FLNA	7.26e-04	19	62	2	C0013366
Disease	Osteochondrodysplasias	HSPG2 FLNA	7.26e-04	19	62	2	C0029422
Disease	Multiple Epiphyseal Dysplasia	HSPG2 FLNA	8.05e-04	20	62	2	C0026760
Disease	Involutional paraphrenia	SLC6A4 FREM3	1.26e-03	25	62	2	C1571983
Disease	Psychosis, Involutional	SLC6A4 FREM3	1.26e-03	25	62	2	C1571984
Disease	Involutional Depression	SLC6A4 FREM3	1.26e-03	25	62	2	C0011574
Disease	pulmonary hypertension (is_implicated_in)	SLC6A4 VWF	1.82e-03	30	62	2	DOID:6432 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
NIVENPCPEILGVDV	C2orf16	806	Q68DN1
VCNVEVGLQTQERPP	AFF3	186	P51826
SVANVIQQAGCPVPE	DDX52	526	Q9Y2R4
LVCGPNAIEVEIQPI	ATP13A5	181	Q4VNC0
EQNGTPIVICPVTQE	BTNL8	451	Q6UX41
EIQPAILQVPCLQGT	ALPK2	1446	Q86TB3
SICQQNGIVPIVEPE	ALDOC	176	P09972
SICQQNGLVPIVEPE	ALDOB	176	P05062
SICQQNGIVPIVEPE	ALDOA	176	P04075
CEPGVNPEEQLIIIQ	DIXDC1	326	Q155Q3
VAQQPLSLVGCEVVP	AFAP1L2	391	Q8N4X5
AQVPEQQPITLCSGV	RC3H1	76	Q5TC82
VGQQLDPIQREPVCA	RANBP10	556	Q6VN20
GQCLPETNQAPLVVE	HSPG2	1666	P98160
EIVTNPPDICQVVEV	IRF2	191	P14316
QPVDPTCRVLVVVGQ	AFMID	231	Q63HM1
EQGIICENIPIVTPS	ABCD1	471	P33897
GPNQIHQIFCDLVPV	OR6K3	186	Q8NGY3
EVQVPPGTRAQDIQC	NUDCD2	31	Q8WVJ2
IIPSDQNIPVGICNV	HECTD2	536	Q5U5R9
PGPDQLQQFQVVCET	DDX56	226	Q9NY93
VCPPGGIQEVTINQS	KRT1	146	P04264
IQVALVVQLPFCGPN	OR4S2	156	Q8NH73
QIPRVVQEGDVLCVP	PEX6	346	Q13608
QEPGQQGIVPQLCED	KIF1C	111	O43896
TQGETQPTCLDVIVP	LMTK2	836	Q8IWU2
QVQVKPEQGCPVGSD	GLI1	811	P08151
LCDIGIPQQVFQEVG	EDC3	476	Q96F86
LCPAGPIQAVEIQVE	FAAP100	776	Q0VG06
PPGTLVQCQQIVKVI	IQSEC3	1086	Q9UPP2
PLQITDTQQGCIAPV	NHLRC2	706	Q8NBF2
QLQDVGLQTPQPVQC	RNF144A	121	P50876
PELVQGNVCPLVNEV	BPIFA1	216	Q9NP55
GQPNILICIVDNIFP	HLA-DOA	126	P06340
IIPGQLNITVECVPV	DOCK11	581	Q5JSL3
PLRVQVQDNEGCPVE	FLNA	706	P21333
ISVAENGLQCPTPQV	SLC44A4	101	Q53GD3
VIRCPEPGENVATQN	FAM135B	476	Q49AJ0
VQVQVTVLPVDNVGP	FREM3	1056	P0C091
GQTEIQVNCPPAVTE	SYPL1	56	Q16563
VNCVAPVDIILPQIT	RIF1	2296	Q5UIP0
VGIPTCESVVQLQPG	FSD2	521	A1L4K1
LECVQAQAVIVPIVP	MORC4	156	Q8TE76
QPGETIQSQIKCTPI	TGM4	641	P49221
EIPLVVCITEGIPQQ	SUCLG1	136	P53597
QDEDIPPITCVQNGL	COL1A1	31	P02452
VPVDGNKEEPQICVI	CTPS2	131	Q9NRF8
IIIGGVATVVCQPNE	SEPHS2	221	Q99611
PAEICVVIGGVRNQQ	ZNF618	96	Q5T7W0
VQRPGQTCQPILEEQ	VWF	2116	P04275
HPNVDENGQICLPII	UBE2L6	76	O14933
PVGVVCQVDGVPQVV	UAP1L1	291	Q3KQV9
GDEPCQIISINPNEV	PKHD1L1	1866	Q86WI1
VIVQVITQVGQPTCC	ZNF717	251	Q9BY31
LQVPEFQACPQTVVP	ZNF496	316	Q96IT1
VPSQQQGICKEEPAQ	ZNF74	121	Q16587
VVPCTQASQRPAVVQ	SNAPC4	756	Q5SXM2
LIQQLDVCVEIPQQG	TARBP1	1576	Q13395
DCPENIRLIVQNPVV	USP34	2811	Q70CQ2
QNPPTNLTVVTVEGC	ABI3BP	831	Q7Z7G0
CQENGVLQKVVPTPG	SLC6A4	21	P31645
LQVQRQVPVPEGLCV	SIGLEC11	36	Q96RL6
QVPVPEGLCVIVSCN	SIGLEC11	41	Q96RL6
TLEPGQPVTVICVFN	SIGLEC11	166	Q96RL6
VQRQVPVPEGLCVIV	SIGLEC16	26	A6NMB1
QIVNTCPQDTGVILI	UBASH3A	571	P57075
PDQQVVINCAIVRGV	VASP	56	P50552