Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone chaperone activity	IPO9 NAP1L1 APLF SPTY2D1	5.46e-08	15	52	4	GO:0140713
GeneOntologyMolecularFunction	protein carrier chaperone	IPO9 NAP1L1 APLF SPTY2D1	2.83e-06	38	52	4	GO:0140597
GeneOntologyMolecularFunction	histone binding	RAG2 IPO9 NAP1L1 TAF1 TAF1L APLF SPTY2D1	5.38e-06	265	52	7	GO:0042393
GeneOntologyMolecularFunction	H3K27me3 modified histone binding	TAF1 TAF1L	6.62e-05	5	52	2	GO:0061628
GeneOntologyMolecularFunction	ubiquitin conjugating enzyme activity	UBE2R2 TAF1 TAF1L	1.22e-04	37	52	3	GO:0061631
GeneOntologyMolecularFunction	molecular carrier activity	IPO9 NAP1L1 APLF SPTY2D1	1.79e-04	108	52	4	GO:0140104
GeneOntologyMolecularFunction	ubiquitin-like protein conjugating enzyme activity	UBE2R2 TAF1 TAF1L	1.91e-04	43	52	3	GO:0061650
GeneOntologyMolecularFunction	ubiquitin-protein transferase activity	RAG2 UBE2R2 CUL9 TAF1 ARIH1 RNF180 TAF1L	2.13e-04	473	52	7	GO:0004842
GeneOntologyMolecularFunction	RNA polymerase I general transcription initiation factor activity	TAF1 TAF1L	2.37e-04	9	52	2	GO:0001181
GeneOntologyMolecularFunction	complement component C1q complex binding	C4A C4B	2.95e-04	10	52	2	GO:0001849
GeneOntologyMolecularFunction	ubiquitin-like protein transferase activity	RAG2 UBE2R2 CUL9 TAF1 ARIH1 RNF180 TAF1L	3.45e-04	512	52	7	GO:0019787
GeneOntologyMolecularFunction	aminoacyltransferase activity	RAG2 UBE2R2 CUL9 TAF1 ARIH1 RNF180 TAF1L	4.34e-04	532	52	7	GO:0016755
GeneOntologyMolecularFunction	chromatin binding	RAG2 KMT5B SUPT16H NAP1L1 TAF1 UPF1 TAF1L BAP1	6.03e-04	739	52	8	GO:0003682
GeneOntologyMolecularFunction	general transcription initiation factor binding	BDP1 TAF1 TAF1L	6.20e-04	64	52	3	GO:0140296
GeneOntologyMolecularFunction	p53 binding	BLM TAF1 TAF1L	1.06e-03	77	52	3	GO:0002039
GeneOntologyMolecularFunction	methylated histone binding	RAG2 TAF1 TAF1L	1.46e-03	86	52	3	GO:0035064
GeneOntologyMolecularFunction	methylation-dependent protein binding	RAG2 TAF1 TAF1L	1.56e-03	88	52	3	GO:0140034
GeneOntologyMolecularFunction	RNA polymerase II core promoter sequence-specific DNA binding	TAF1 TAF1L	1.92e-03	25	52	2	GO:0000979
GeneOntologyMolecularFunction	opsonin binding	C4A C4B	1.92e-03	25	52	2	GO:0001846
GeneOntologyMolecularFunction	zinc ion binding	BLM RAG2 USP13 ZNF330 DNAJC21 CUL9 UPF1 ARIH1	2.00e-03	891	52	8	GO:0008270
GeneOntologyMolecularFunction	modification-dependent protein binding	RAG2 TAF1 TAF1L APLF	2.02e-03	206	52	4	GO:0140030
GeneOntologyMolecularFunction	RNA polymerase II general transcription initiation factor binding	TAF1 TAF1L	2.24e-03	27	52	2	GO:0001091
GeneOntologyMolecularFunction	lysine-acetylated histone binding	TAF1 TAF1L	2.76e-03	30	52	2	GO:0070577
GeneOntologyMolecularFunction	acetylation-dependent protein binding	TAF1 TAF1L	2.95e-03	31	52	2	GO:0140033
GeneOntologyMolecularFunction	phosphatidylinositol-3,5-bisphosphate binding	RAG2 CLVS2	2.95e-03	31	52	2	GO:0080025
GeneOntologyMolecularFunction	histone modifying activity	KMT5B TAF1 TAF1L BAP1	2.96e-03	229	52	4	GO:0140993
GeneOntologyMolecularFunction	complement binding	C4A C4B	3.14e-03	32	52	2	GO:0001848
GeneOntologyMolecularFunction	transition metal ion binding	BLM RAG2 USP13 ZNF330 DNAJC21 CUL9 APLP2 UPF1 ARIH1	3.30e-03	1189	52	9	GO:0046914
GeneOntologyMolecularFunction	TBP-class protein binding	TAF1 TAF1L	3.34e-03	33	52	2	GO:0017025
GeneOntologyMolecularFunction	acyltransferase activity	RAG2 UBE2R2 CUL9 TAF1 ARIH1 RNF180 TAF1L	3.78e-03	775	52	7	GO:0016746
GeneOntologyMolecularFunction	ubiquitin conjugating enzyme binding	ARIH1 RNF180	3.96e-03	36	52	2	GO:0031624
GeneOntologyMolecularFunction	transcription regulator inhibitor activity	TAF1 TAF1L	3.96e-03	36	52	2	GO:0140416
GeneOntologyMolecularFunction	telomeric DNA binding	BLM UPF1	4.87e-03	40	52	2	GO:0042162
GeneOntologyMolecularFunction	ubiquitin-like protein conjugating enzyme binding	ARIH1 RNF180	5.36e-03	42	52	2	GO:0044390
GeneOntologyBiologicalProcess	protein-DNA complex assembly	BDP1 SUPT16H NAP1L1 TAF1 TAF1L SPTY2D1	3.73e-05	249	52	6	GO:0065004
GeneOntologyCellularComponent	pronucleus	BLM TAF1 TAF1L	4.29e-05	28	51	3	GO:0045120
GeneOntologyCellularComponent	symbiont cell surface	C4A C4B	1.62e-04	8	51	2	GO:0106139
GeneOntologyCellularComponent	other organism part	C4A C4B	2.08e-04	9	51	2	GO:0044217
HumanPheno	Retinopathy	BLM MIA3 MLX JAZF1 C4A C4B BAP1	1.36e-06	142	22	7	HP:0000488
HumanPheno	Malar rash	BLM JAZF1 C4A C4B	1.94e-05	39	22	4	HP:0025300
HumanPheno	Malaise	MLX JAZF1 C4A C4B	3.46e-05	45	22	4	HP:0033834
HumanPheno	Skin rash	BLM RAG2 JAZF1 DNAJC21 C4A C4B	6.46e-05	172	22	6	HP:0000988
HumanPheno	Reduced impulse control	TNIK SOX5 PIEZO2 MLX KMT5B GAS1 SUPT16H JAZF1 DNAJC21 C4A C4B TAF1 BAP1	7.16e-05	1032	22	13	HP:5200045
HumanPheno	Abnormality of skin physiology	BLM SOX5 RAG2 MIA3 MLX JAZF1 DNAJC21 C4A C4B TAF1	7.42e-05	593	22	10	HP:0011122
HumanPheno	Cheilitis	BLM JAZF1 C4A C4B	9.50e-05	58	22	4	HP:0100825
HumanPheno	Short attention span	TNIK SOX5 PIEZO2 KMT5B GAS1 SUPT16H DNAJC21 TAF1 BAP1	1.58e-04	517	22	9	HP:0000736
HumanPheno	Reduced attention regulation	TNIK SOX5 PIEZO2 KMT5B GAS1 SUPT16H DNAJC21 TAF1 BAP1	1.81e-04	526	22	9	HP:5200044
HumanPheno	Attention deficit hyperactivity disorder	TNIK SOX5 PIEZO2 KMT5B GAS1 SUPT16H TAF1 BAP1	2.02e-04	413	22	8	HP:0007018
HumanPheno	Oral ulcer	JAZF1 DNAJC21 C4A C4B	2.10e-04	71	22	4	HP:0000155
HumanPheno	Anti-complement component C1q antibody positivity	JAZF1 C4A C4B	2.63e-04	30	22	3	HP:0034077
HumanPheno	Anti-ribosome Po antibody positivity	JAZF1 C4A C4B	2.63e-04	30	22	3	HP:0034076
HumanPheno	Anti-phosphatidic acid antibody positivity	JAZF1 C4A C4B	2.63e-04	30	22	3	HP:0034096
HumanPheno	Anti-Ro52/TRIM21 antibody positivity	JAZF1 C4A C4B	2.63e-04	30	22	3	HP:0034093
HumanPheno	Anti-La/SS-B antibody positivity	JAZF1 C4A C4B	2.63e-04	30	22	3	HP:0032235
HumanPheno	Anti-nucleoporin 62 antibody positivity	JAZF1 C4A C4B	2.63e-04	30	22	3	HP:0033556
HumanPheno	Anti-titin antibody positivity	JAZF1 C4A C4B	2.63e-04	30	22	3	HP:5000038
HumanPheno	Hyperactivity	TNIK SOX5 PIEZO2 KMT5B GAS1 SUPT16H DNAJC21 TAF1 BAP1	2.85e-04	558	22	9	HP:0000752
HumanPheno	Pyuria	JAZF1 C4A C4B	2.91e-04	31	22	3	HP:0012085
HumanPheno	Lupus nephritis	JAZF1 C4A C4B	3.20e-04	32	22	3	HP:0033726
HumanPheno	Anti-U1 ribonucleoprotein antibody positivity	JAZF1 C4A C4B	3.20e-04	32	22	3	HP:0033028
HumanPheno	Anti-Sm antibody positivity	JAZF1 C4A C4B	3.20e-04	32	22	3	HP:0033040
HumanPheno	Extractable nuclear antigen positivity	JAZF1 C4A C4B	3.84e-04	34	22	3	HP:0033476
HumanPheno	Anti-dsDNA antibody positivity	JAZF1 C4A C4B	3.84e-04	34	22	3	HP:0020151
HumanPheno	Decreased circulating complement C4 concentration	JAZF1 C4A C4B	4.19e-04	35	22	3	HP:0045042
HumanPheno	Lymphadenopathy	RAG2 SH3BP2 JAZF1 C4A C4B BAP1	4.84e-04	248	22	6	HP:0002716
HumanPheno	Abnormal retinal morphology	BLM MIA3 PIEZO2 DST MLX SH3BP2 JAZF1 DNAJC21 C4A C4B PRPF6 BAP1	5.21e-04	1065	22	12	HP:0000479
HumanPheno	Chromosome breakage	BLM DNAJC21 BAP1	5.35e-04	38	22	3	HP:0040012
HumanPheno	Discoid lupus rash	JAZF1 C4A C4B	5.78e-04	39	22	3	HP:0007417
HumanPheno	Alopecia	BLM RAG2 JAZF1 C4A C4B BAP1	6.36e-04	261	22	6	HP:0001596
HumanPheno	Abnormal lymph node morphology	RAG2 SH3BP2 JAZF1 C4A C4B BAP1	6.62e-04	263	22	6	HP:0002733
HumanPheno	Decreased circulating complement C3 concentration	JAZF1 C4A C4B	7.72e-04	43	22	3	HP:0005421
HumanPheno	Recurrent maladaptive behavior	TNIK SOX5 PIEZO2 MLX KMT5B GAS1 SUPT16H JAZF1 DNAJC21 C4A C4B TAF1 BAP1	7.98e-04	1293	22	13	HP:5200241
HumanPheno	Abnormal pigmentation of the oral mucosa	JAZF1 C4A C4B	8.26e-04	44	22	3	HP:0100669
HumanPheno	Serositis	JAZF1 C4A C4B PLCE1	8.71e-04	103	22	4	HP:0045073
HumanPheno	Erosion of oral mucosa	JAZF1 DNAJC21 C4A C4B	9.37e-04	105	22	4	HP:0031446
Domain	TAF_II_230-bd	TAF1 TAF1L	7.60e-06	2	52	2	IPR009067
Domain	TFIID_sub1_DUF3591	TAF1 TAF1L	7.60e-06	2	52	2	IPR022591
Domain	-	TAF1 TAF1L	7.60e-06	2	52	2	1.10.1100.10
Domain	TBP-binding	TAF1 TAF1L	7.60e-06	2	52	2	PF09247
Domain	DUF3591	TAF1 TAF1L	7.60e-06	2	52	2	PF12157
Domain	TAF1_animal	TAF1 TAF1L	7.60e-06	2	52	2	IPR011177
Domain	Anaphylatoxin_comp_syst	C4A C4B	7.56e-05	5	52	2	IPR018081
Domain	Anaphylatoxn_comp_syst_dom	C4A C4B	7.56e-05	5	52	2	IPR001840
Domain	ANATO	C4A C4B	1.58e-04	7	52	2	SM00104
Domain	ANATO	C4A C4B	1.58e-04	7	52	2	PF01821
Domain	ANAPHYLATOXIN_2	C4A C4B	1.58e-04	7	52	2	PS01178
Domain	ANAPHYLATOXIN_1	C4A C4B	1.58e-04	7	52	2	PS01177
Domain	Anaphylatoxin/fibulin	C4A C4B	1.58e-04	7	52	2	IPR000020
Domain	Thiol-ester_cl	C4A C4B	2.11e-04	8	52	2	PF10569
Domain	MacrogloblnA2_thiol-ester-bond	C4A C4B	2.11e-04	8	52	2	IPR019565
Domain	MacrogloblnA2_CS	C4A C4B	2.11e-04	8	52	2	IPR019742
Domain	A2M_N	C4A C4B	3.37e-04	10	52	2	PF01835
Domain	A2M_N	C4A C4B	3.37e-04	10	52	2	IPR002890
Domain	A-macroglobulin_rcpt-bd	C4A C4B	3.37e-04	10	52	2	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	C4A C4B	3.37e-04	10	52	2	PS00477
Domain	A2M	C4A C4B	3.37e-04	10	52	2	PF00207
Domain	A2M_N_2	C4A C4B	3.37e-04	10	52	2	IPR011625
Domain	A2M_comp	C4A C4B	3.37e-04	10	52	2	IPR011626
Domain	A2M_N_2	C4A C4B	3.37e-04	10	52	2	PF07703
Domain	A2M_recep	C4A C4B	3.37e-04	10	52	2	PF07677
Domain	A2M_comp	C4A C4B	3.37e-04	10	52	2	PF07678
Domain	Macroglobln_a2	C4A C4B	3.37e-04	10	52	2	IPR001599
Domain	IBR	CUL9 ARIH1	6.77e-04	14	52	2	SM00647
Domain	IBR	CUL9 ARIH1	6.77e-04	14	52	2	PF01485
Domain	IBR_dom	CUL9 ARIH1	7.80e-04	15	52	2	IPR002867
Domain	C345C	C4A C4B	1.01e-03	17	52	2	SM00643
Domain	Terpenoid_cyclase/PrenylTrfase	C4A C4B	1.13e-03	18	52	2	IPR008930
Domain	NTR	C4A C4B	1.26e-03	19	52	2	PF01759
Domain	Netrin_module_non-TIMP	C4A C4B	1.26e-03	19	52	2	IPR018933
Domain	NTR	C4A C4B	1.85e-03	23	52	2	PS50189
Domain	Netrin_domain	C4A C4B	1.85e-03	23	52	2	IPR001134
Domain	Bromodomain_CS	TAF1 TAF1L	2.37e-03	26	52	2	IPR018359
Domain	TIMP-like_OB-fold	C4A C4B	2.37e-03	26	52	2	IPR008993
Domain	BROMODOMAIN_1	TAF1 TAF1L	4.76e-03	37	52	2	PS00633
Domain	Bromodomain	TAF1 TAF1L	5.01e-03	38	52	2	PF00439
Pathway	REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_PHOSPHORYLATION	BLM SUPT16H TAF1 TAF1L	8.53e-05	92	36	4	MM15338
Pathway	REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_PHOSPHORYLATION	BLM SUPT16H TAF1 TAF1L	8.53e-05	92	36	4	M27636
Pathway	REACTOME_ACTIVATION_OF_C3_AND_C5	C4A C4B	1.32e-04	7	36	2	MM14685
Pathway	KEGG_MEDICUS_REFERENCE_CLASSICAL_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION	C4A C4B	1.76e-04	8	36	2	M47872
Pathway	REACTOME_ACTIVATION_OF_C3_AND_C5	C4A C4B	1.76e-04	8	36	2	M27031
Pathway	REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_TRANSPORT_AND_UPTAKE_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS	MIA3 APLP2 C4A C4B	2.38e-04	120	36	4	MM14982
Pathway	KEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION	C4A C4B	3.44e-04	11	36	2	M47874
Pathway	BIOCARTA_LECTIN_PATHWAY	C4A C4B	3.44e-04	11	36	2	MM1430
Pathway	BIOCARTA_CLASSIC_PATHWAY	C4A C4B	4.12e-04	12	36	2	MM1368
Pathway	BIOCARTA_LECTIN_PATHWAY	C4A C4B	4.86e-04	13	36	2	M4732
Pathway	BIOCARTA_CLASSIC_PATHWAY	C4A C4B	6.52e-04	15	36	2	M7146
Pathway	REACTOME_REGULATION_OF_TP53_ACTIVITY	BLM SUPT16H TAF1 TAF1L	6.61e-04	157	36	4	MM15226
Pathway	REACTOME_REGULATION_OF_TP53_ACTIVITY	BLM SUPT16H TAF1 TAF1L	7.09e-04	160	36	4	M27498
Pathway	REACTOME_TRANSCRIPTION_OF_THE_HIV_GENOME	SUPT16H TAF1 TAF1L	7.44e-04	70	36	3	M27008
Pathway	WP_COMPLEMENT_ACTIVATION_CLASSICAL_PATHWAY	C4A C4B	8.42e-04	17	36	2	MM15944
Pathway	BIOCARTA_COMP_PATHWAY	C4A C4B	8.42e-04	17	36	2	MM1369
Pathway	REACTOME_RNA_POLYMERASE_II_PRE_TRANSCRIPTION_EVENTS	SUPT16H TAF1 TAF1L	1.14e-03	81	36	3	M865
Pathway	BIOCARTA_COMP_PATHWAY	C4A C4B	1.17e-03	20	36	2	M917
Pathway	REACTOME_RNA_POLYMERASE_II_PRE_TRANSCRIPTION_EVENTS	SUPT16H TAF1 TAF1L	1.22e-03	83	36	3	MM15314
Pathway	WP_COMPLEMENT_ACTIVATION	C4A C4B	1.42e-03	22	36	2	M39502
Pathway	BIOCARTA_VDR_PATHWAY	SUPT16H COPS2	1.69e-03	24	36	2	M13404
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	PCSK5 USP13 HBS1L MIA3 DST GSE1 DNAJC21 C4A C4B PLCE1	3.79e-08	650	52	10	38777146
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	BLM USP13 EAPP SUPT16H NAP1L1 NVL PRPF6 TAF1 UPF1 ARIH1 COPS2	2.48e-07	1014	52	11	32416067
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	BLM HBS1L MIA3 RBM10 SUPT16H NVL PRPF6 UPF1	2.85e-07	440	52	8	34244565
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	BLM BDP1 DNAJC21 NID1 C4A C4B PRPF6 COPS2	7.13e-07	497	52	8	36774506
Pubmed	Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.	SUPT16H NAP1L1 NVL NID1 APLP2 UPF1	2.05e-06	251	52	6	28077445
Pubmed	Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.	C4A C4B	2.19e-06	2	52	2	22737222
Pubmed	Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.	C4A C4B	2.19e-06	2	52	2	16565498
Pubmed	Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.	C4A C4B	2.19e-06	2	52	2	15998580
Pubmed	Structural polymorphism of murine C4 and its linkage to H-2.	C4A C4B	2.19e-06	2	52	2	7373044
Pubmed	High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.	C4A C4B	2.19e-06	2	52	2	19062096
Pubmed	The chemical structure of the C4d fragment of the human complement component C4.	C4A C4B	2.19e-06	2	52	2	3696167
Pubmed	Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.	C4A C4B	2.19e-06	2	52	2	1357031
Pubmed	Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.	C4A C4B	2.19e-06	2	52	2	16098595
Pubmed	Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.	C4A C4B	2.19e-06	2	52	2	19933335
Pubmed	Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.	C4A C4B	2.19e-06	2	52	2	2459207
Pubmed	Antigen-induced B cell apoptosis is independent of complement C4.	C4A C4B	2.19e-06	2	52	2	17645767
Pubmed	Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.	C4A C4B	2.19e-06	2	52	2	15787745
Pubmed	Anti-DNA autoreactivity in C4-deficient mice.	C4A C4B	2.19e-06	2	52	2	12207352
Pubmed	Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.	C4A C4B	2.19e-06	2	52	2	30026462
Pubmed	A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.	C4A C4B	2.19e-06	2	52	2	6559257
Pubmed	Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.	C4A C4B	2.19e-06	2	52	2	27758680
Pubmed	Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.	C4A C4B	2.19e-06	2	52	2	22387014
Pubmed	Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Spectrum Disorder Subjects.	C4A C4B	2.19e-06	2	52	2	34299197
Pubmed	Assessment of complement C4 gene copy number using the paralog ratio test.	C4A C4B	2.19e-06	2	52	2	20506482
Pubmed	Polymerase chain reaction based C4AQ0 and C4BQ0 genotyping: association with systemic lupus erythematosus in southwest Han Chinese.	C4A C4B	2.19e-06	2	52	2	12480675
Pubmed	Low C4, C4A and C4B gene copy numbers are stronger risk factors for juvenile-onset than for adult-onset systemic lupus erythematosus.	C4A C4B	2.19e-06	2	52	2	26800705
Pubmed	Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.	C4A C4B	2.19e-06	2	52	2	23749435
Pubmed	Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.	C4A C4B	2.19e-06	2	52	2	23918728
Pubmed	Murine complement C4 is not required for experimental autoimmune encephalomyelitis.	C4A C4B	2.19e-06	2	52	2	15390104
Pubmed	Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.	C4A C4B	2.19e-06	2	52	2	3037333
Pubmed	Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.	C4A C4B	2.19e-06	2	52	2	11726230
Pubmed	Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.	C4A C4B	2.19e-06	2	52	2	4216347
Pubmed	Importance of the alpha 3-fragment of complement C4 for the binding with C4b-binding protein.	C4A C4B	2.19e-06	2	52	2	1699796
Pubmed	Sequence determination of the thiolester site of the fourth component of human complement.	C4A C4B	2.19e-06	2	52	2	6950384
Pubmed	Molecular cloning and characterization of complementary and genomic DNA clones for mouse C4 and Slp.	C4A C4B	2.19e-06	2	52	2	2997024
Pubmed	Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.	C4A C4B	2.19e-06	2	52	2	8660986
Pubmed	Constitutive expression of Slp genes in mouse strain B10.WR directed by C4 regulatory sequences.	C4A C4B	2.19e-06	2	52	2	3624865
Pubmed	Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.	C4A C4B	2.19e-06	2	52	2	8428773
Pubmed	Determination of the loss of function complement C4 exon 29 CT insertion using a novel paralog-specific assay in healthy UK and Spanish populations.	C4A C4B	2.19e-06	2	52	2	21857912
Pubmed	Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.	C4A C4B	2.19e-06	2	52	2	24638111
Pubmed	Isolation of cDNA clones specifying the fourth component of mouse complement and its isotype, sex-limited protein.	C4A C4B	2.19e-06	2	52	2	6208559
Pubmed	The role of the histocompatibility-2-linked Ss-Slp region in the control of mouse complement.	C4A C4B	2.19e-06	2	52	2	4514997
Pubmed	Transcriptional repression of C4 complement by hepatitis C virus proteins.	C4A C4B	2.19e-06	2	52	2	21345967
Pubmed	The inheritance of susceptibility to the Gross leukemia virus in mice.	C4A C4B	2.19e-06	2	52	2	5919331
Pubmed	An ancient provirus has imposed androgen regulation on the adjacent mouse sex-limited protein gene.	C4A C4B	2.19e-06	2	52	2	3167981
Pubmed	The dichotomous size variation of human complement C4 genes is mediated by a novel family of endogenous retroviruses, which also establishes species-specific genomic patterns among Old World primates.	C4A C4B	2.19e-06	2	52	2	7545960
Pubmed	Insights on the relationship between complement component C4 serum concentrations and C4 gene copy numbers in a Western Australian systemic lupus erythematosus cohort.	C4A C4B	2.19e-06	2	52	2	30041577
Pubmed	Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.	C4A C4B	2.19e-06	2	52	2	2572548
Pubmed	The complement component C4 of mammals.	C4A C4B	2.19e-06	2	52	2	2302180
Pubmed	Complete cDNA sequence of the fourth component of murine complement.	C4A C4B	2.19e-06	2	52	2	3862104
Pubmed	The BS variant of C4 protects against age-related loss of white matter microstructural integrity.	C4A C4B	2.19e-06	2	52	2	34358307
Pubmed	Acute renal allograft rejection: diagnostic significance of focal peritubular capillary C4d.	C4A C4B	2.19e-06	2	52	2	18360261
Pubmed	Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.	C4A C4B	2.19e-06	2	52	2	22151770
Pubmed	C4d-positive chronic rejection: a frequent entity with a poor outcome.	C4A C4B	2.19e-06	2	52	2	18091514
Pubmed	Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.	C4A C4B	2.19e-06	2	52	2	29080553
Pubmed	Schizophrenia risk from complex variation of complement component 4.	C4A C4B	2.19e-06	2	52	2	26814963
Pubmed	Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.	C4A C4B	2.19e-06	2	52	2	6589636
Pubmed	C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.	C4A C4B	2.19e-06	2	52	2	25339671
Pubmed	A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.	C4A C4B	2.19e-06	2	52	2	17728371
Pubmed	Taf1 knockout is lethal in embryonic male mice and heterozygous females show weight and movement disorders.	TAF1 TAF1L	2.19e-06	2	52	2	38804708
Pubmed	Structure and organization of the C4 genes.	C4A C4B	2.19e-06	2	52	2	6149580
Pubmed	Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.	C4A C4B	2.19e-06	2	52	2	6149581
Pubmed	The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.	C4A C4B	2.19e-06	2	52	2	12115608
Pubmed	Biochemistry and biology of anaphylatoxins.	C4A C4B	2.19e-06	2	52	2	3542363
Pubmed	C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.	C4A C4B	2.19e-06	2	52	2	2387317
Pubmed	Promoter elements of the mouse complement C4 gene critical for transcription activation and start site location.	C4A C4B	2.19e-06	2	52	2	8132550
Pubmed	TAFII250, Egr-1, and D-type cyclin expression in mice and neonatal rat cardiomyocytes treated with doxorubicin.	TAF1 TAF1L	2.19e-06	2	52	2	10070062
Pubmed	Substitution of a single amino acid (aspartic acid for histidine) converts the functional activity of human complement C4B to C4A.	C4A C4B	2.19e-06	2	52	2	2395880
Pubmed	Effects of Complement C4 Gene Copy Number Variations, Size Dichotomy, and C4A Deficiency on Genetic Risk and Clinical Presentation of Systemic Lupus Erythematosus in East Asian Populations.	C4A C4B	2.19e-06	2	52	2	26814708
Pubmed	cDNA clone spanning the alpha-gamma subunit junction in the precursor of the murine fourth complement component (C4).	C4A C4B	2.19e-06	2	52	2	6192448
Pubmed	Sustained expression of a neuron-specific isoform of the Taf1 gene in development stages and aging in mice.	TAF1 TAF1L	2.19e-06	2	52	2	22842574
Pubmed	Complete primary structure of human C4a anaphylatoxin.	C4A C4B	2.19e-06	2	52	2	6167582
Pubmed	Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.	C4A C4B	2.19e-06	2	52	2	16908004
Pubmed	Slp is an essential component of an EDTA-resistant activation pathway of mouse complement.	C4A C4B	2.19e-06	2	52	2	1438267
Pubmed	Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.	C4A C4B	2.19e-06	2	52	2	7365238
Pubmed	Genetic deficiency of complement isoforms C4A or C4B predicts improved survival of metastatic renal cell carcinoma.	C4A C4B	2.19e-06	2	52	2	19150565
Pubmed	Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.	C4A C4B	2.19e-06	2	52	2	7391573
Pubmed	Elevated levels of endogenous apoptotic DNA and IFN-alpha in complement C4-deficient mice: implications for induction of systemic lupus erythematosus.	C4A C4B	2.19e-06	2	52	2	17506029
Pubmed	Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.	C4A C4B	2.19e-06	2	52	2	17971360
Pubmed	Low C4 gene copy numbers are associated with superior graft survival in patients transplanted with a deceased donor kidney.	C4A C4B	2.19e-06	2	52	2	23715124
Pubmed	Identification of the 5'-flanking regulatory region responsible for the difference in transcriptional control between mouse complement C4 and Slp genes.	C4A C4B	2.19e-06	2	52	2	3464002
Pubmed	Complete nucleotide and derived amino acid sequences of the fourth component of mouse complement (C4). Evolutionary aspects.	C4A C4B	2.19e-06	2	52	2	2993295
Pubmed	Clinical features of patients with homozygous complement C4A or C4B deficiency.	C4A C4B	2.19e-06	2	52	2	29928053
Pubmed	Frameshift Mutations in the Mononucleotide Repeats of TAF1 and TAF1L Genes in Gastric and Colorectal Cancers with Regional Heterogeneity.	TAF1 TAF1L	2.19e-06	2	52	2	27571988
Pubmed	Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.	C4A C4B	2.19e-06	2	52	2	17971229
Pubmed	Striatal Cholinergic Dysregulation after Neonatal Decrease in X-Linked Dystonia Parkinsonism-Related TAF1 Isoforms.	TAF1 TAF1L	2.19e-06	2	52	2	34403156
Pubmed	Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease. Genetic and immunologic studies.	C4A C4B	2.19e-06	2	52	2	6881182
Pubmed	Identification of the site of sulfation of the fourth component of human complement.	C4A C4B	2.19e-06	2	52	2	3944109
Pubmed	Partial C4 deficiency in juvenile idiopathic arthritis patients.	C4A C4B	2.19e-06	2	52	2	17921792
Pubmed	Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant.	C4A C4B	2.19e-06	2	52	2	21880985
Pubmed	Amino acid sequence around the thiol and reactive acyl groups of human complement component C4.	C4A C4B	2.19e-06	2	52	2	6978711
Pubmed	Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD.	C4A C4B	2.19e-06	2	52	2	35898513
Pubmed	Overexpression of schizophrenia susceptibility factor human complement C4A promotes excessive synaptic loss and behavioral changes in mice.	C4A C4B	2.19e-06	2	52	2	33353966
Pubmed	Sequence comparison of alleles of the fourth component of complement (C4) and sex-limited protein (Slp).	C4A C4B	2.19e-06	2	52	2	3008092
Pubmed	Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival.	C4A C4B	2.19e-06	2	52	2	28873507
Pubmed	The molecular basis for the difference in immune hemolysis activity of the Chido and Rodgers isotypes of human complement component C4.	C4A C4B	2.19e-06	2	52	2	6609966
Pubmed	Heterogeneity and linkage of equine C4 and steroid 21-hydroxylase genes.	C4A C4B	2.19e-06	2	52	2	2900855
Pubmed	Studies on the murine Ss protein: demonstration that the Ss protein is functionally the fourth component of complement.	C4A C4B	2.19e-06	2	52	2	276882
Pubmed	Amino acid sequence of a polymorphic segment from fragment C4d of human complement component C4.	C4A C4B	2.19e-06	2	52	2	6832377
Pubmed	Recombination of two homologous MHC class III genes of the mouse (C4 and Slp) that accounts for the loss of testosterone dependence of sex-limited protein expression.	C4A C4B	2.19e-06	2	52	2	3794341
Interaction	CSNK2A1 interactions	BDP1 UBE2R2 USP13 DST MLX CCDC82 RBM10 SUPT16H NAP1L1 CUL9 TAF1 UPF1 COPS2 BAP1	8.70e-08	956	52	14	int:CSNK2A1
Interaction	ZNF330 interactions	BLM IPO9 ZNF330 SUPT16H NAP1L1 NVL PRPF6 TAF1 SPTY2D1	1.86e-06	446	52	9	int:ZNF330
Interaction	ZIC2 interactions	TNIK TAF1 ARIH1 RNF180	3.03e-06	39	52	4	int:ZIC2
Interaction	DCTN1 interactions	CEP350 IPO9 DST SUPT16H NAP1L1 DNAJC21 SLAIN1 UPF1 BAP1	4.50e-06	497	52	9	int:DCTN1
Interaction	H2AC8 interactions	IPO9 EID1 SUPT16H NAP1L1 APLF SPTY2D1	6.14e-06	177	52	6	int:H2AC8
Interaction	FBXO22 interactions	BLM BDP1 DNAJC21 NID1 C4A C4B PRPF6 ARIH1 COPS2	8.78e-06	540	52	9	int:FBXO22
Interaction	NOP56 interactions	BLM TNIK MIA3 ZNF330 SUPT16H NAP1L1 PRPF6 SPTY2D1 BAP1	1.35e-05	570	52	9	int:NOP56
Interaction	SUPT16H interactions	TNIK CCDC82 ZNF330 SUPT16H NAP1L1 PRPF6 APLF BAP1	1.62e-05	442	52	8	int:SUPT16H
Interaction	XRCC6 interactions	BLM GSE1 ZNF330 RBM10 EID1 SUPT16H NVL TAF1 TAF1L APLF BAP1	1.98e-05	928	52	11	int:XRCC6
Interaction	TULP3 interactions	UBE2R2 HBS1L DST GSE1 SLAIN1 ARIH1 COPS2	2.85e-05	346	52	7	int:TULP3
Interaction	PDS5A interactions	USP13 ZNF330 RBM10 PRPF6 ZNF654 BAP1	3.87e-05	245	52	6	int:PDS5A
Interaction	SRP14 interactions	BLM USP13 IPO9 NVL DNAJC21 ARIH1 BAP1	4.08e-05	366	52	7	int:SRP14
Interaction	CEP19 interactions	CEP350 HBS1L IPO9 NVL UPF1	5.21e-05	157	52	5	int:CEP19
Interaction	RPL31 interactions	BLM SUPT16H NAP1L1 NVL PRPF6 TAF1 UPF1 SPTY2D1 BAP1	5.40e-05	680	52	9	int:RPL31
Interaction	CDC5L interactions	TNIK IPO9 DST EAPP GSE1 RBM10 PRPF6 UPF1 COPS2 BAP1	5.61e-05	855	52	10	int:CDC5L
Interaction	SSRP1 interactions	CCDC82 ZNF330 RBM10 SUPT16H NAP1L1 PRPF6 APLF SPTY2D1 BAP1	5.71e-05	685	52	9	int:SSRP1
Interaction	SFN interactions	CEP350 TNIK UBE2R2 STOX2 IPO9 DST SUPT16H APLP2 BAP1	6.17e-05	692	52	9	int:SFN
Interaction	AGRN interactions	TNIK IPO9 SUPT16H DNAJC21 RNF180 COPS2	6.24e-05	267	52	6	int:AGRN
Interaction	KLHL4 interactions	MIA3 ARIH1 COPS2	8.37e-05	33	52	3	int:KLHL4
Interaction	HMGB3 interactions	IPO9 ZNF330 SUPT16H BAP1	9.31e-05	92	52	4	int:HMGB3
Interaction	H2BC1 interactions	IPO9 SUPT16H NAP1L1 JAZF1 APLF	9.44e-05	178	52	5	int:H2BC1
Interaction	FNTA interactions	BLM TNIK NAP1L1 BAP1	1.01e-04	94	52	4	int:FNTA
Interaction	UBC interactions	USP13 DST ZNF330 NVL DNAJC21 APLP2 COPS2	1.40e-04	446	52	7	int:UBC
Interaction	PHIP interactions	GSE1 ZNF330 SUPT16H TAF1 COPS2	1.52e-04	197	52	5	int:PHIP
Interaction	USP39 interactions	EAPP SUPT16H PRPF6 ARIH1 BAP1	1.67e-04	201	52	5	int:USP39
Interaction	HECTD1 interactions	BLM HBS1L SUPT16H NAP1L1 NVL DNAJC21 PRPF6 TAF1 UPF1 SPTY2D1	1.79e-04	984	52	10	int:HECTD1
Interaction	SIRT6 interactions	BLM HBS1L MIA3 RBM10 SUPT16H NVL PRPF6 UPF1	1.91e-04	628	52	8	int:SIRT6
Interaction	UHRF1 interactions	HBS1L IPO9 ZNF330 SUPT16H ARIH1	1.96e-04	208	52	5	int:UHRF1
Interaction	SNRNP40 interactions	BLM GSE1 RBM10 SUPT16H CUL9 PRPF6 COPS2 SPTY2D1	2.10e-04	637	52	8	int:SNRNP40
Interaction	NAP1L1 interactions	IPO9 ZNF330 SUPT16H NAP1L1 COPS2 BAP1	2.53e-04	345	52	6	int:NAP1L1
Interaction	CASK interactions	TNIK MLX RBM10 CUL9 ARIH1	2.59e-04	221	52	5	int:CASK
Interaction	UIMC1 interactions	BLM USP13 PRPF6 COPS2	2.68e-04	121	52	4	int:UIMC1
Interaction	EXOSC10 interactions	HBS1L ZNF330 NVL UPF1 BAP1	2.70e-04	223	52	5	int:EXOSC10
Interaction	H2AC19 interactions	IPO9 SUPT16H APLF	2.92e-04	50	52	3	int:H2AC19
Interaction	H2AC4 interactions	BLM IPO9 SUPT16H NAP1L1 PRPF6 APLF BAP1	3.04e-04	506	52	7	int:H2AC4
Interaction	PYHIN1 interactions	SUPT16H NAP1L1 NVL NID1 APLP2 UPF1	3.08e-04	358	52	6	int:PYHIN1
Interaction	RPL7A interactions	ZNF330 RBM10 NAP1L1 NVL DNAJC21 UPF1 SPTY2D1 BAP1	3.23e-04	679	52	8	int:RPL7A
Interaction	H2AC17 interactions	BLM IPO9 SUPT16H NAP1L1 APLF	3.24e-04	232	52	5	int:H2AC17
Interaction	PRPF31 interactions	USP13 ZNF330 SLAIN1 PRPF6 ARIH1 BAP1	3.89e-04	374	52	6	int:PRPF31
Interaction	ECT2 interactions	BLM IPO9 DST SUPT16H NAP1L1 NVL PRPF6 UPF1 ARIH1	3.98e-04	887	52	9	int:ECT2
Interaction	MAGED2 interactions	TNIK EID1 NAP1L1 JAZF1 BAP1	4.01e-04	243	52	5	int:MAGED2
Interaction	ASF1A interactions	BLM BDP1 GSE1 TAF1 SPTY2D1	4.48e-04	249	52	5	int:ASF1A
Interaction	EWSR1 interactions	TNIK SOX5 MIA3 MLX SUPT16H PRPF6 TAF1 UPF1 BAP1	4.65e-04	906	52	9	int:EWSR1
Interaction	CSNK2A2 interactions	UBE2R2 MLX CCDC82 RBM10 SUPT16H NAP1L1 COPS2 BAP1	4.69e-04	718	52	8	int:CSNK2A2
Interaction	SNAI1 interactions	BLM USP13 IPO9 GSE1 RBM10 PRPF6 UPF1	4.80e-04	546	52	7	int:SNAI1
Interaction	ZFP82 interactions	ZNF330 ARIH1	5.00e-04	13	52	2	int:ZFP82
Cytoband	Xq13.1	RTL5 TAF1	1.37e-03	48	52	2	Xq13.1
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C4A C4B	8.88e-05	9	29	2	1234
GeneFamily	Complement system\|Sushi domain containing	C4A C4B	1.51e-03	36	29	2	492
GeneFamily	Glycosyltransferase family 6\|Blood group antigens	C4A C4B	1.60e-03	37	29	2	454
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	CEP350 BLM PCSK5 BDP1 STOX2 PIEZO2 NAP1L1 NID1 ZNF654	5.13e-06	656	52	9	M18979
Coexpression	GSE369_IFNG_KO_VS_WT_LIVER_UP	GSE1 CCDC82 KMT5B DNAJC21 SLAIN1	4.67e-05	199	52	5	M5970
Coexpression	GSE8685_IL2_STARVED_VS_IL2_ACT_IL2_STARVED_CD4_TCELL_UP	MIA3 CCDC82 KMT5B JAZF1 SLAIN1	4.67e-05	199	52	5	M324
Coexpression	GSE6674_ANTI_IGM_VS_PL2_3_STIM_BCELL_DN	BLM BDP1 IPO9 MLX DNAJC21	4.67e-05	199	52	5	M6932
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 KMT5B GAS1 SUPT16H PRPF6	1.94e-06	176	52	5	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	COPD-Endothelial-Lymphatic\|Endothelial / Disease state, Lineage and Cell class	STOX2 PIEZO2 DST NID1 PLCE1	3.20e-06	195	52	5	e91ce548ae7224661ee5d2f2639794a5f69798ee
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PCSK5 PIEZO2 DST GAS1 NID1	3.20e-06	195	52	5	f54bc4454270ff06e85596f98199372b50d0179f
ToppCell	Control-Endothelial-Lymphatic\|Endothelial / Disease state, Lineage and Cell class	STOX2 PIEZO2 DST NID1 PLCE1	3.28e-06	196	52	5	e0cf617b0f5d9c3c19574f587a3d0ccbf93d8ca4
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CUL9 C4A C4B PLCE1	1.30e-05	123	52	4	a45d6907c041ad3f3218cd46dccfc25d4bd961cb
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Myocytic\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SOX5 CLVS2 NID1 PLCE1	3.31e-05	156	52	4	6365b69ede98bc866e996bc52736b00401aacf6f
ToppCell	facs-Aorta-Heart-18m-Mesenchymal-fibrocyte\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLVS2 SH3BP2 SLAIN1 C4A	3.31e-05	156	52	4	5b56217336771baf57d791efcb4e206c6aea83b1
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CEP350 USP13 NAP1L1 PLCE1	5.65e-05	179	52	4	d15182c668d7c37be8214cad9f1fe35d1409c9a1
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CEP350 USP13 NAP1L1 PLCE1	5.65e-05	179	52	4	e22a275a7c0ed19113c833a75d6c49fcc19aa13a
ToppCell	droplet-Lung-LUNG-30m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST APLP2 PNPLA7 RNF180	5.90e-05	181	52	4	8fcdab61fad2efd324d2b27c58f5a594f1dc15de
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STOX2 PIEZO2 DST NID1	6.16e-05	183	52	4	4d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SOX5 CLVS2 NID1 PLCE1	6.16e-05	183	52	4	8a799807fbf24456a9811e0c64068187940a2f71
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BLM SOX5 NACC2 PLCE1	6.29e-05	184	52	4	2ba98708dfd7f1b2a661578a334684094ff453ad
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SOX5 CLVS2 NID1 PLCE1	6.29e-05	184	52	4	327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	CEP350 TNIK TAF1 SPTY2D1	6.56e-05	186	52	4	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	PCW_13-14\|World / Celltypes from embryonic and fetal-stage human lung	TNIK PIEZO2 DST GSE1	7.12e-05	190	52	4	62a3ec1ae0829602b0569cc051210551644f1d46
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 KMT5B DNAJC21 APLP2	7.27e-05	191	52	4	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SOX5 USP13 STOX2 SLAIN1	7.27e-05	191	52	4	ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCell	ASK454-Mesenchymal-Fibroblast\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	PCSK5 PIEZO2 DST GAS1	7.27e-05	191	52	4	1726add3f392a061536b7aff72ba84303f4a0b1f
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 PIEZO2 GSE1 NID1	7.27e-05	191	52	4	1caf726bd07fdca389e678fc16304a6ef1790423
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 KMT5B DNAJC21 APLP2	7.27e-05	191	52	4	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 PIEZO2 GSE1 NID1	7.27e-05	191	52	4	3d60c46bced2984c27a1fcf2910bc38b31fb0148
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 KMT5B DNAJC21 APLP2	7.27e-05	191	52	4	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	ASK454-Mesenchymal\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	PCSK5 PIEZO2 DST GAS1	7.27e-05	191	52	4	e30ae7a12439f8a79820b13f03e822c1223fd0cb
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 PIEZO2 GSE1 NID1	7.41e-05	192	52	4	4022f208eb5db760abd0aac782a25e8ab63efc64
ToppCell	LPS_only-Stromal_mesenchymal\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SOX5 PIEZO2 GAS1 NID1	7.41e-05	192	52	4	162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 PIEZO2 GSE1 NID1	7.41e-05	192	52	4	9333aba0d04203ccccad78d82bf6359922f810a7
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TNIK PIEZO2 DST PLCE1	7.72e-05	194	52	4	35f132cc38ac133be01834ed0946188aa0757eb4
ToppCell	LPS-antiTNF-Stromal_mesenchymal\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SOX5 PIEZO2 GAS1 NID1	7.72e-05	194	52	4	6e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 PIEZO2 DST NID1	7.72e-05	194	52	4	90efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 PIEZO2 DST NID1	7.72e-05	194	52	4	df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SOX5 PIEZO2 DST GSE1	7.72e-05	194	52	4	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	COVID-19-Fibroblasts-Alveolar_FB\|COVID-19 / group, cell type (main and fine annotations)	SOX5 PIEZO2 DST NID1	7.87e-05	195	52	4	603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell	facs-Thymus-Thymus_Epithelium\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 PIEZO2 GAS1 NID1	8.03e-05	196	52	4	6bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCell	facs-Thymus-Thymus_Epithelium-18m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 PIEZO2 GAS1 NID1	8.03e-05	196	52	4	c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell	Children_(3_yrs)-Mesenchymal\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SOX5 PIEZO2 DST NID1	8.03e-05	196	52	4	bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell	facs-Lung-nan\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAS1 NID1 C4B PLCE1	8.03e-05	196	52	4	b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCell	facs-Lung-nan-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAS1 NID1 C4B PLCE1	8.03e-05	196	52	4	787c6cd92035e0b1108c2c086c42a229016e476b
ToppCell	Mild\|World / Condition, Lineage, Cell class and cell subclass	CEP350 BDP1 MIA3 DST	8.19e-05	197	52	4	476b0d0389f9fcd4614f6bb1f494281f467f6730
ToppCell	ILEUM-inflamed-(6)_ILC-(6)_ILC3\|(6)_ILC / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	DST EID1 NAP1L1 PRPF6	8.51e-05	199	52	4	02879df850b0c72b57d7b22cfc43f3407e182dcb
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Classical_Monocyte\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	UBE2R2 NACC2 NID1 APLP2	8.51e-05	199	52	4	c40cb51c738b15d2761a50cfc8415a31a673be7f
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	CEP350 DST NAP1L1 DNAJC21	8.51e-05	199	52	4	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Monocytic\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	UBE2R2 NACC2 NID1 APLP2	8.68e-05	200	52	4	9e8659bbc6547f1ab7f4e0a81b0bcbe158e9e2f7
ToppCell	cellseq-Mesenchymal-Fibroblastic\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PIEZO2 DST GAS1 NID1	8.68e-05	200	52	4	8978867bf69c830b1e48cac2ad6b512dbe60f149
ToppCell	critical-Epithelial-FOXN4+\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CEP350 BLM USP13 PLCE1	8.68e-05	200	52	4	f39db4250ce220a3eb58edee3f7fc3671701d46f
ToppCell	wk_15-18-Mesenchymal\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PIEZO2 DST EID1 NID1	8.68e-05	200	52	4	4d484260ecbbbd9f820b445bdcc2666f6c464b73
ToppCell	Parenchymal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_endoneurial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	PCSK5 GAS1 BAP1	6.45e-04	145	52	3	e808502fa52baf1c400f3c9b918a167127e78af9
ToppCell	TCGA-Thymus-Primary_Tumor-Thymoma-Type_AB-8\|TCGA-Thymus / Sample_Type by Project: Shred V9	SOX5 PIEZO2 PLCE1	7.26e-04	151	52	3	5906562efd36fbcb91f96e0a0d3a8fe999ba1e79
ToppCell	PND07-28-samps-Mesenchymal-Mesothelial-Mesothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	JAZF1 SLAIN1 PLCE1	7.98e-04	156	52	3	605d95a900e1443d3f6aae163ef2e893d3293203
ToppCell	PND07-28-samps-Mesenchymal-Mesothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	JAZF1 SLAIN1 PLCE1	7.98e-04	156	52	3	574f761962a7dd3308bd41fc529dd3ea1b8625f8
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CLVS2 NID1 PLCE1	8.13e-04	157	52	3	bfec34182f052cf1c0d847ba53ea335d4d1190de
ToppCell	wk_20-22-Hematologic_Lymphocytic-T_&_ILC-T_entry\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	PCSK5 RAG2 GSE1	8.90e-04	162	52	3	a27750117e7f16a0bd07cc5f58a56becb39e800b
ToppCell	368C-Myeloid-Dendritic-cDC_activated\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CEP350 STOX2 RNF180	9.22e-04	164	52	3	67c636a2cc32e56c6186dc7e779cc19af04639d2
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	PCSK5 GAS1 BAP1	9.22e-04	164	52	3	d6806deabf5f5c355934387be2baae125ac33fb8
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 PIEZO2 RTL5	9.22e-04	164	52	3	b6df1e67a5ce5f2d86f4e1420f4ee931f760bf4d
ToppCell	368C-Myeloid-Dendritic-cDC_activated\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	CEP350 STOX2 RNF180	9.38e-04	165	52	3	9d2bdc42c13c8c2a68889bec8612a1ce56f659fa
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SOX5 NAP1L1 NID1	9.55e-04	166	52	3	94636dbc039f794c735960c3425e00bdd5523602
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_E\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	RTL5 GAS1 ZNF654	9.71e-04	167	52	3	b5d15773be32cd277125fd3b4056a8fefaefa5ec
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GAS1 C4B PLCE1	9.71e-04	167	52	3	d50311b1f66f143bae4c4cf50e2e9b13c85d6920
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GAS1 C4B PLCE1	9.71e-04	167	52	3	351f8de1fbdf742ac74f9099b254d515ab539bb2
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GAS1 C4B PLCE1	9.71e-04	167	52	3	c042d6cdddd0e1ddef1e3ac6f4fe23151127b0f2
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GAS1 C4B PLCE1	9.71e-04	167	52	3	7abc785e688a384672d7fb5a62d32538fe7e5a51
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-TRGV4_gdT\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GAS1 SLAIN1 APLF	1.02e-03	170	52	3	65c7ed586e7615203a59999549892ed466a89502
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNIK UBE2R2 TAF1	1.02e-03	170	52	3	adb625124832b0786a590e8f75b61e7263a1e0d4
ToppCell	Severe-B_naive-11\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	RTL5 JAZF1 APLP2	1.04e-03	171	52	3	7c2699f19ca38414447a286f7658f507882d57c2
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	IPO9 DNAJC21 NID1	1.04e-03	171	52	3	2a34685f7d83d1cf9a88d304173cbca868c5f9fd
ToppCell	5'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EECs\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX5 RTL5 CUL9	1.04e-03	171	52	3	dd37e1693a5cfc42e40992d504f92048a8038b52
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	USP13 STOX2 PIEZO2	1.08e-03	173	52	3	7dc988fc0ba29990567bf1bcdeb3faeeee507eb1
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GAS1 C4B PLCE1	1.08e-03	173	52	3	3725525b99a6011eda2ff5459b4fd2e1eab1f090
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D122\|Adult / Lineage, Cell type, age group and donor	STOX2 PIEZO2 NID1	1.08e-03	173	52	3	dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCell	Adult-Mesenchymal-pericyte_cell-D175\|Adult / Lineage, Cell type, age group and donor	SOX5 NID1 PLCE1	1.08e-03	173	52	3	fd6653d6be9ca6ac36798590694efe03cb758c67
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GAS1 C4B PLCE1	1.08e-03	173	52	3	ee7d1429f23f1b89a9a9f7bc07a84a44cf7acd1c
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GAS1 C4B PLCE1	1.08e-03	173	52	3	30d67738633493d47f06ae452424382f069b6c0a
ToppCell	Endothelial-B-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	PIEZO2 NID1 PLCE1	1.08e-03	173	52	3	a81992965137195d20fc498f750975303961a828
ToppCell	PND07-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TNIK GSE1 NACC2	1.09e-03	174	52	3	a3f4981b10afa9d41a1c66c7f98522a8a534f82b
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	IPO9 DST SLAIN1	1.09e-03	174	52	3	2274648b80dd74f3c948a779bba3391095964c34
ToppCell	PND07-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TNIK GSE1 NACC2	1.09e-03	174	52	3	6cc108dde4b3f98a78a6040280f0d5e4aaa5bd75
ToppCell	PND07-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TNIK GSE1 NACC2	1.09e-03	174	52	3	4b8bc5568e36031c8ecf001bb646809038c23919
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GAS1 C4B PLCE1	1.09e-03	174	52	3	a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCell	Control-Epithelial_cells-AT1\|Control / group, cell type (main and fine annotations)	STOX2 DST PLCE1	1.09e-03	174	52	3	548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TNIK UBE2R2 DST	1.11e-03	175	52	3	e99e145a152f534b75267ec492a252a0b814b4f8
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L2-4_SST_AHR\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BLM PCSK5 PIEZO2	1.13e-03	176	52	3	322259a35f5c97d73ce7f75835dcdb5c954c91f8
ToppCell	droplet-Fat-Mat-18m-Hematologic-monocyte\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAZF1 SLAIN1 PNPLA7	1.13e-03	176	52	3	867936a20f73f638055c19c8d88834aa2cc657cf
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L2-4_SST_AHR\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BLM PCSK5 PIEZO2	1.13e-03	176	52	3	014aa4a9aeae37309d7e05b20a06893a50f10bfe
ToppCell	COVID-19-Heart-Lymph_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	STOX2 PIEZO2 PLCE1	1.15e-03	177	52	3	326fde0734ef0d7272693966d346ca479b9d8147
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SOX5 NID1 PLCE1	1.17e-03	178	52	3	185b44700f06ec58b3c09c80520502166c965fd6
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GAS1 C4B PLCE1	1.17e-03	178	52	3	c413861148129be1ee94f2ceb5999840217eebe5
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-5\|TCGA-Skin / Sample_Type by Project: Shred V9	RTL5 NID1 PLCE1	1.17e-03	178	52	3	ad5cd505ca1cef8ac29b2af7e2c3e01ebc140c14
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	PIEZO2 NID1 PRPF6	1.17e-03	178	52	3	edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STOX2 PIEZO2 DST	1.17e-03	178	52	3	ad3de3e03a401dac64431a541899445262246347
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GAS1 C4B PLCE1	1.17e-03	178	52	3	c77a1d1a9aef0ab51b4408b9e84f201219788ca2
ToppCell	droplet-Spleen-nan-21m-Lymphocytic-B_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX5 NAP1L1 NID1	1.17e-03	178	52	3	0265c0bc005c05fd5906a88c1eafd17891e952f1
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GAS1 C4B PLCE1	1.17e-03	178	52	3	bcbdd45a2307f8aea14122fa0144b96b1f6eec48
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_atypical-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SOX5 BAP1 PLCE1	1.19e-03	179	52	3	5be883d7d0be3180bb9844e4a757f0dd247294e4
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SOX5 STOX2 SLAIN1	1.19e-03	179	52	3	815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BLM PIEZO2 PLCE1	1.19e-03	179	52	3	d1365d48d1b017a7917f4f63a82ac4720c3d87df
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX5 PIEZO2 NID1	1.19e-03	179	52	3	a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 PIEZO2 NID1	1.20e-03	180	52	3	fdbd7c22044d9328a1e06e2f9a4451529d1df767
ToppCell	IPF-Epithelial-Mesothelial\|IPF / Disease state, Lineage and Cell class	GAS1 C4A C4B	1.20e-03	180	52	3	1fa54bf4dba72866b2295639d991af639341bc08
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 PIEZO2 NID1	1.20e-03	180	52	3	280ff5c8f292be1b88120db5ff1788b750644856
Disease	response to hydrochlorothiazide, triglyceride measurement	STOX2 PIEZO2 JAZF1	7.48e-05	47	51	3	EFO_0004530, EFO_0005202
Disease	Lupus Erythematosus, Systemic	JAZF1 C4A C4B	2.56e-04	71	51	3	C0024141
Disease	Immunologic Deficiency Syndromes	BLM C4A	7.24e-04	23	51	2	C0021051
Disease	phosphatidylcholine 38:4 measurement	GAS1 JAZF1	1.08e-03	28	51	2	EFO_0010386
Disease	non-high density lipoprotein cholesterol measurement	PCSK5 HBS1L JAZF1 APLP2 SPTY2D1 PLCE1	1.39e-03	713	51	6	EFO_0005689
Disease	Complement deficiency disease	C4A C4B	1.49e-03	33	51	2	C0272242
Disease	LDL peak particle diameter measurement, total fat intake measurement	SOX5 MIA3	1.59e-03	34	51	2	EFO_0007677, EFO_0007678
Disease	pulse pressure measurement, diastolic blood pressure, systolic blood pressure, hypertension	GSE1 CLVS2	1.68e-03	35	51	2	EFO_0000537, EFO_0005763, EFO_0006335, EFO_0006336

Protein segments in the cluster

Peptide	Gene	Start	Entry
DDADDFESDYEEESY	BDP1	1876	A6H8Y1
EYDLNDSFLDDEEED	APLF	461	Q8IW19
DDFMCDDEEDYDLEY	COPS2	6	P61201
DDEEDYDLEYSEDSN	COPS2	11	P61201
MEANEDYEDYEYDEL	C4B	1411	P0C0L5
YYDLDDSYDESDEEE	GSE1	756	Q14687
NEDYEHDDEDDSYLE	SH3BP2	171	P78314
YYDDIYFDSDSEDED	EAPP	101	Q56P03
PQQYSDDEDDYEDDE	BAP1	391	Q92560
TYNEDDEEDESETGY	RAG2	401	P55895
DYDDSSEEQSAEDSY	RBM10	56	P98175
YFTGEAIEDDDDDYD	NAP1L1	341	P55209
EEDNEYTESYSDDDS	NVL	91	O15381
NYDEDFEDDDLYGQS	HBS1L	11	Q9Y450
FEDDDLYGQSVEDDY	HBS1L	16	Q9Y450
DDEDSDYHQEAYKES	MLX	111	Q9UH92
GYNYEFDEDEECSEE	ARIH1	6	Q9Y4X5
EEDEEEDYDVYKSEF	APLP2	226	Q06481
YIYDSNDQDDDDDDG	DST	2586	Q03001
DDYSQYEEESTDDSS	KMT5B	816	Q4FZB7
EYDEEEVDYEESDSD	JAZF1	131	Q86VZ6
EFDDWEDDYDYPEEE	EID1	101	Q9Y6B2
RDRDYDEDDDDDIVY	PCSK5	1811	Q92824
GAEYDDEDEDYDLAT	NID1	286	P14543
LDDYYDEDYDDEQRT	GAS1	261	P54826
DSDEAEDAELYDDLY	DNAJC21	301	Q5F1R6
DESDYQTEYEEELLD	PNPLA7	1256	Q6ZV29
AELNFEEDEEDTYYT	UPF1	101	Q92900
EDNYESDEDGDDYII	CCDC82	281	Q8N4S0
YDIDNFDIDDFDDDD	BLM	551	P54132
DDYVDINEDEDCYSD	CEP350	2571	Q5VT06
TSKYEEDYYEDDEED	IPO9	976	Q96P70
EDYYEDDEEDDPDAL	IPO9	981	Q96P70
FDEELDNDSFSYDES	CUL9	2481	Q8IWT3
MEANEDYEDYEYDEL	C4A	1411	P0C0L4
STDEDNEYAEEKDSY	RNF180	416	Q86T96
EESEDEEYYSEDEDQ	RTL5	336	Q5HYW3
DDFDEELDTEYYAVG	MIA3	301	Q5JRA6
EDEYDYDYESLSDDN	PLCE1	1586	Q9P212
ADDDDEDLNDTNYDE	PRPF6	66	O94906
SDYDEDDYDADCEDI	TAF1L	136	Q8IZX4
HSDYDEDDYDADCED	TAF1	136	P21675
QEYDQYSLEDEEEFD	SLAIN1	316	Q8ND83
YKRQREYEEEDDDDD	SPTY2D1	581	Q68D10
DSDEDYSSEAEESDY	SUPT16H	961	Q9Y5B9
LDHEYDDDSEYNVDS	CLVS2	266	Q5SYC1
YEYSGSEEEEEENDS	TNIK	321	Q9UKE5
FDYYNVSDDDDSEEG	STOX2	771	Q9P2F5
YYLFETDSEEEEEEE	PIEZO2	1551	Q9H5I5
EEGDYEEDDYDLNQE	ZNF654	706	Q8IZM8
YDEYDEEEDDPDVDY	SOX5	736	P35711
SYHDEEEDEYEAEDD	ZNF330	266	Q9Y3S2
LYDDLYDDDIDDEDE	UBE2R2	206	Q712K3
DTDDDLNSDDYEYED	USP13	121	Q92995
TSYHNEEDEEDDEAY	NACC2	261	Q96BF6