Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-19 ERVK-24	2.42e-10	37	148	8	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-19 ERVK-24	3.05e-10	38	148	8	GO:0070001
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-6 ERVK-7 ERVK-10 NYNRIN ERVK-8	9.32e-09	11	148	5	GO:0004523
GeneOntologyMolecularFunction	RNA-directed DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8	2.74e-06	14	148	4	GO:0003964
GeneOntologyMolecularFunction	RNA endonuclease activity, producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 NYNRIN ERVK-8	7.53e-06	37	148	5	GO:0016891
GeneOntologyMolecularFunction	DNA polymerase activity	ERVK-6 POLG ERVK-7 ERVK-10 ERVK-8	8.61e-06	38	148	5	GO:0034061
GeneOntologyMolecularFunction	zinc ion binding	ERVK-6 UBR4 AIRE CHD3 ERVK-7 ERVK-21 ERVK-9 NR6A1 ERVK-10 POLR3A ZBTB32 UBR5 TRIM28 ERVK-8 ERVK-19 SNCA ERVK-24 ZNF282 TRIM37 ZMYM3	9.70e-06	891	148	20	GO:0008270
GeneOntologyMolecularFunction	RNA stem-loop binding	ERVK-6 ERVK-7 ERVK-10 ERVK-8	1.57e-05	21	148	4	GO:0035613
GeneOntologyMolecularFunction	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 NYNRIN ERVK-8	2.24e-05	46	148	5	GO:0016893
GeneOntologyMolecularFunction	P-type manganese transporter activity	ATP2C1 ATP2C2	5.46e-05	2	148	2	GO:0140613
GeneOntologyMolecularFunction	nuclease activity	ERVK-6 POLG ANGEL1 ERVK-7 ERVK-10 NYNRIN ERVK-8 N4BP1 LAS1L	5.78e-05	231	148	9	GO:0004518
GeneOntologyMolecularFunction	transition metal ion binding	ERVK-6 UBR4 AIRE XDH CHD3 ERVK-7 ERVK-21 ERVK-9 NR6A1 ERVK-10 POLR3A ATP2C1 ZBTB32 UBR5 TRIM28 ERVK-8 ERVK-19 SNCA ERVK-24 ZNF282 TRIM37 ZMYM3	6.54e-05	1189	148	22	GO:0046914
GeneOntologyMolecularFunction	RNA nuclease activity	ERVK-6 ANGEL1 ERVK-7 ERVK-10 NYNRIN ERVK-8 N4BP1	7.01e-05	136	148	7	GO:0004540
GeneOntologyMolecularFunction	RNA endonuclease activity	ERVK-6 ERVK-7 ERVK-10 NYNRIN ERVK-8	3.03e-04	79	148	5	GO:0004521
GeneOntologyMolecularFunction	calmodulin binding	SPTAN1 UBR4 ITPKB PHKG2 SCN3A MAPKAPK3 FKBP8 CAMSAP1	3.24e-04	230	148	8	GO:0005516
GeneOntologyMolecularFunction	extracellular matrix structural constituent conferring tensile strength	COL2A1 COL5A1 COL11A2 COL15A1	3.71e-04	46	148	4	GO:0030020
GeneOntologyMolecularFunction	endonuclease activity	ERVK-6 ERVK-7 ERVK-10 NYNRIN ERVK-8 LAS1L	5.34e-04	136	148	6	GO:0004519
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	SCN1A SCN3A CACNA1I	9.15e-04	26	148	3	GO:0005248
GeneOntologyMolecularFunction	nucleotidyltransferase activity	ERVK-6 POLG ERVK-7 ERVK-10 POLR3A ERVK-8	9.56e-04	152	148	6	GO:0016779
GeneOntologyMolecularFunction	structural molecule activity	COL2A1 ERVK-6 COL5A1 COL11A2 COL15A1 MAP1A SPTAN1 ERVK-7 ERVK-21 ERVK-9 ERVK-10 AHNAK ERVK-8 ERVK-19 ERVK-24 TNXB	9.57e-04	891	148	16	GO:0005198
GeneOntologyMolecularFunction	chromatin binding	POLG APBB1 AIRE CHD3 KDM6B BAHD1 STAT1 POLR3A PWWP2A NCOR2 KDM4D TNRC18 TRIM28 TRIM37	1.21e-03	739	148	14	GO:0003682
GeneOntologyBiologicalProcess	DNA integration	ERVK-6 ERVK-7 ERVK-10 NYNRIN ERVK-8	2.11e-08	13	147	5	GO:0015074
GeneOntologyBiologicalProcess	Golgi organization	GOLGA8T BLZF1 GOLGA8Q COG8 GOLGA8N TBC1D20 TMED3 GOLGA8IP PLK3	3.35e-06	168	147	9	GO:0007030
GeneOntologyBiologicalProcess	DNA synthesis involved in DNA repair	ERVK-6 ERVK-7 ERVK-10 NYNRIN ERVK-8	2.30e-05	48	147	5	GO:0000731
GeneOntologyBiologicalProcess	cell-cell fusion	ERVK-6 ERVK-21 ERVK-9 STAT1 ERVK-8 ERVK-19	3.26e-05	85	147	6	GO:0140253
GeneOntologyBiologicalProcess	syncytium formation by plasma membrane fusion	ERVK-6 ERVK-21 ERVK-9 STAT1 ERVK-8 ERVK-19	3.26e-05	85	147	6	GO:0000768
GeneOntologyBiologicalProcess	syncytium formation	ERVK-6 ERVK-21 ERVK-9 STAT1 ERVK-8 ERVK-19	4.23e-05	89	147	6	GO:0006949
GeneOntologyBiologicalProcess	membrane depolarization during action potential	KCNH2 SCN1A SCN3A CACNA1I	1.22e-04	36	147	4	GO:0086010
GeneOntologyBiologicalProcess	viral process	ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 STAT1 TBC1D20 TRIM28 ERVK-8 ERVK-19 N4BP1 ERVK-24	1.26e-04	464	147	12	GO:0016032
GeneOntologyBiologicalProcess	cytoplasm protein quality control by the ubiquitin-proteasome system	UBR4 UBR5	1.51e-04	3	147	2	GO:0071629
GeneOntologyBiologicalProcess	cytoplasm protein quality control	UBR4 UBR5	1.51e-04	3	147	2	GO:0140455
GeneOntologyCellularComponent	cis-Golgi network	GOLGA8T ANGEL1 BLZF1 GOLGA8Q GOLGA8N GOLGA8IP ATP2C1	2.63e-06	85	150	7	GO:0005801
GeneOntologyCellularComponent	collagen type XI trimer	COL2A1 COL5A1 COL11A2	3.58e-06	5	150	3	GO:0005592
GeneOntologyCellularComponent	Golgi cisterna membrane	GOLGA8T GOLGA8Q GOLGA8N TMED3 GOLGA8IP ATP2C1	5.98e-05	94	150	6	GO:0032580
GeneOntologyCellularComponent	fibrillar collagen trimer	COL2A1 COL5A1 COL11A2	7.60e-05	12	150	3	GO:0005583
GeneOntologyCellularComponent	banded collagen fibril	COL2A1 COL5A1 COL11A2	7.60e-05	12	150	3	GO:0098643
GeneOntologyCellularComponent	Golgi cis cisterna	GOLGA8T GOLGA8Q GOLGA8N GOLGA8IP	8.86e-05	33	150	4	GO:0000137
GeneOntologyCellularComponent	voltage-gated sodium channel complex	SCN1A SCN3A CACNA1I	2.29e-04	17	150	3	GO:0001518
GeneOntologyCellularComponent	Golgi stack	GOLGA8T GOLGA8Q GOLGA8N TMED3 GOLGA8IP ATP2C1 PLK3	2.39e-04	171	150	7	GO:0005795
GeneOntologyCellularComponent	Golgi cisterna	GOLGA8T GOLGA8Q GOLGA8N TMED3 GOLGA8IP ATP2C1	4.34e-04	135	150	6	GO:0031985
GeneOntologyCellularComponent	complex of collagen trimers	COL2A1 COL5A1 COL11A2	4.38e-04	21	150	3	GO:0098644
GeneOntologyCellularComponent	main axon	MAP1A SPTAN1 APBB1 GJC2 SCN1A	4.55e-04	89	150	5	GO:0044304
GeneOntologyCellularComponent	nuclear body	PABIR1 SETD1B FLYWCH1 RTEL1 APBB1 AIRE MECOM CHD3 PASD1 NCBP3 NCOR2 PSME4 SCN1A PRPF19 N4BP1 MTREX	7.88e-04	903	150	16	GO:0016604
GeneOntologyCellularComponent	sodium channel complex	SCN1A SCN3A CACNA1I	1.15e-03	29	150	3	GO:0034706
GeneOntologyCellularComponent	Golgi apparatus subcompartment	GOLGA8T GOLGA8Q COG8 GOLGA8N TMED3 GOLGA8IP ATP2C1 ATP2C2 PLK3 RAB11FIP3	1.38e-03	443	150	10	GO:0098791
Domain	P-type_ATPase_IIA_PMR1	ATP2C1 ATP2C2	5.26e-05	2	136	2	IPR006413
Domain	NC1_FIB	COL2A1 COL5A1 COL11A2	5.97e-05	11	136	3	PS51461
Domain	Fib_collagen_C	COL2A1 COL5A1 COL11A2	5.97e-05	11	136	3	PD002078
Domain	Fib_collagen_C	COL2A1 COL5A1 COL11A2	5.97e-05	11	136	3	IPR000885
Domain	COLFI	COL2A1 COL5A1 COL11A2	5.97e-05	11	136	3	PF01410
Domain	COLFI	COL2A1 COL5A1 COL11A2	5.97e-05	11	136	3	SM00038
Pubmed	Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.	ERVK-6 ERVK-7 ERVK-10 ERVK-24	3.60e-10	4	153	4	10469592
Pubmed	Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.	ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19	1.19e-09	12	153	5	14557543
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-6 ERVK-7 ERVK-21 ERVK-19	1.79e-09	5	153	4	12629516
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TFEB SETD1B TRIO POLG UBR4 KDM6B BAHD1 TYK2 NCOR2 TNRC18 PSME4 PTPRF TRIM28 KCNH2 AHNAK ANKRD11 CAMSAP1 SIPA1L2 PLK3 PLXNA1 RAI1 RAB11FIP3	3.66e-09	1105	153	22	35748872
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-19 ERVK-24	9.43e-09	94	153	8	21542922
Pubmed	Collagen XI chain misassembly in cartilage of the chondrodysplasia (cho) mouse.	COL2A1 COL5A1 COL11A2	3.33e-07	4	153	3	17683922
Pubmed	Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.	ERVK-6 ERVK-10 ERVK-19	3.33e-07	4	153	3	7983737
Pubmed	TRIM37 deficiency induces autophagy through deregulating the MTORC1-TFEB axis.	TFEB RRAGB TRIM37	8.29e-07	5	153	3	29940807
Pubmed	Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.	ERVK-21 ERVK-9 ERVK-10 ERVK-24	1.05e-06	18	153	4	18664271
Pubmed	Regulation of collagen fibril nucleation and initial fibril assembly involves coordinate interactions with collagens V and XI in developing tendon.	COL2A1 COL5A1 COL11A2	1.65e-06	6	153	3	21467034
Pubmed	The collagen family members as cell adhesion proteins.	COL2A1 COL5A1 COL11A2	1.65e-06	6	153	3	17876790
Pubmed	Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.	ERVK-6 ERVK-9 ERVK-19	1.65e-06	6	153	3	15063128
Pubmed	Developmental pattern of expression of the mouse alpha 1 (XI) collagen gene (Col11a1).	COL2A1 COL5A1 COL11A2	1.65e-06	6	153	3	8563024
Pubmed	The pro-alpha2(XI) collagen gene is expressed in odontoblasts.	COL2A1 COL5A1 COL11A2	4.60e-06	8	153	3	20059976
Pubmed	Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration.	FMNL3 CAMSAP1 ZMYM3 BRWD1	7.85e-06	29	153	4	21834987
Pubmed	Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.	ERVK-6 ERVK-21 ERVK-19	9.79e-06	10	153	3	12970426
Pubmed	A directed protein interaction network for investigating intracellular signal transduction.	DDR1 COL11A2 SPTAN1 UBR4 APBB1 TSEN54 CHD3 TSSC4 KDM6B BAHD1 TYK2 MAPKAPK3 SNCA ZNF282 ACAP3 GOT2 RAI1	1.01e-05	1124	153	17	21900206
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	TRIO SPTAN1 CHD3 TNRC18 TRIM28 AHNAK ANKRD11 SOHLH1 CAMSAP1	1.77e-05	332	153	9	37433992
Pubmed	Secretory pathway Ca2+ -ATPases promote in vitro microcalcifications in breast cancer cells.	ATP2C1 ATP2C2	1.92e-05	2	153	2	28618103
Pubmed	Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2alpha subunit of NuRD.	CHD3 TRIM28	1.92e-05	2	153	2	11230151
Pubmed	Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.	SCN1A SCN3A	1.92e-05	2	153	2	24990319
Pubmed	Sumoylation of the transcriptional intermediary factor 1beta (TIF1beta), the Co-repressor of the KRAB Multifinger proteins, is required for its transcriptional activity and is modulated by the KRAB domain.	TRIM28 ZNF74	1.92e-05	2	153	2	17298944
Pubmed	TRIM28 represses transcription of endogenous retroviruses in neural progenitor cells.	NES TRIM28	1.92e-05	2	153	2	25543143
Pubmed	Mapping of a FEB3 homologous febrile seizure locus on mouse chromosome 2 containing candidate genes Scn1a and Scn3a.	SCN1A SCN3A	1.92e-05	2	153	2	27690330
Pubmed	Dissection of the functional differences between human secretory pathway Ca2+/Mn2+-ATPase (SPCA) 1 and 2 isoenzymes by steady-state and transient kinetic analyses.	ATP2C1 ATP2C2	1.92e-05	2	153	2	16332677
Pubmed	The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains.	TRIO PTPRF	1.92e-05	2	153	2	8643598
Pubmed	Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome.	SCN1A SCN3A	1.92e-05	2	153	2	23965409
Pubmed	Increased Levels of the Parkinson's Disease-Associated Gene ITPKB Correlate with Higher Expression Levels of α-Synuclein, Independent of Mutation Status.	ITPKB SNCA	1.92e-05	2	153	2	36768321
Pubmed	Rab11-dependent Recycling of the Human Ether-a-go-go-related Gene (hERG) Channel.	RAB11FIP1 KCNH2	1.92e-05	2	153	2	26152716
Pubmed	More knee joint osteoarthritis (OA) in mice after inactivation of one allele of type II procollagen gene but less OA after lifelong voluntary wheel running exercise.	COL2A1 COL11A2	1.92e-05	2	153	2	11237662
Pubmed	A SPLICS reporter reveals [Formula: see text]-synuclein regulation of lysosome-mitochondria contacts which affects TFEB nuclear translocation.	TFEB SNCA	1.92e-05	2	153	2	38374070
Pubmed	Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.	ERVK-6 ERVK-19	1.92e-05	2	153	2	9060628
Pubmed	Genetic and chemical activation of TFEB mediates clearance of aggregated α-synuclein.	TFEB SNCA	1.92e-05	2	153	2	25790376
Pubmed	Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.	ERVK-6 ERVK-19	1.92e-05	2	153	2	9460924
Pubmed	Intracellular signal transduction of interferon on the suppression of haematopoietic progenitor cell growth.	STAT1 TYK2	1.92e-05	2	153	2	14617019
Pubmed	ADAP restraint of STAT1 signaling regulates macrophage phagocytosis in immune thrombocytopenia.	STAT1 FYB1	1.92e-05	2	153	2	35637282
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	FLYWCH1 ARID4A UBR4 MECOM ALX4 STAT1 NCOR2 PHKG2 UBR5 ANAPC1 MAPKAPK3 CCDC15 CAMSAP1 ZMYM3	2.78e-05	857	153	14	25609649
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	PABIR1 TFEB NES TRIO SPTAN1 APBB1 RAB11FIP1 ITPKB AHNAK ANKRD11 TSC22D4 MTREX CAMSAP1 SIPA1L2	2.92e-05	861	153	14	36931259
Pubmed	Identification of host proteins required for HIV infection through a functional genomic screen.	KLHL1 SPTAN1 RRAGB BAHD1 POLR3A TMEM132C NCOR2 KDM4D	2.94e-05	272	153	8	18187620
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	NES SETD1B SPTAN1 UBR4 PPIL4 TSSC4 STAT1 POLR3A NCOR2 PSME4 UBR5 TRIM28 AHNAK PRPF19 MTREX LAS1L ZMYM3 GOT2	3.02e-05	1353	153	18	29467282
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	COL5A1 DDR1 TRIO RTEL1 POLG TOM1 CHD3 ALX4 ITPKB TYK2 NCOR2 TNRC18 ATP2C1 TESMIN ANKRD11 TSC22D4 SYTL1 RAI1 PDZD2	3.16e-05	1489	153	19	28611215
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	COL5A1 NES SPTAN1 UBR4 KRI1 UBR5 ANAPC1 AHNAK MTREX LAS1L ZMYM3 RAI1	3.46e-05	653	153	12	22586326
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	MAP1A ANGEL1 MECOM CHD3 RAB11FIP1 TYK2 NCOR2 ATP2C1 UBR5 ANAPC1 TRIM28 FKBP8 SIPA1L2 ZMYM3 RAI1 BRWD1	3.56e-05	1116	153	16	31753913
Pubmed	Perlecan maintains the integrity of cartilage and some basement membranes.	COL2A1 NES COL11A2	3.65e-05	15	153	3	10579729
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	UBR4 MECOM CHD3 TNRC18 UBR5 ANAPC1 MTREX LAS1L	3.79e-05	282	153	8	23667531
Pubmed	The functional interactome landscape of the human histone deacetylase family.	ARID4A CHD3 PWWP2A NCOR2 TNRC18 UBR5 ANKRD11 ZMYM3	4.51e-05	289	153	8	23752268
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	MAP1A TRIO SPTAN1 UBR4 APBB1 RTN1 TNRC18 ATP2C1 TRIM28 AJM1 SCN1A FKBP8 SNCA CAMSAP1 SIPA1L2 PHACTR1	4.53e-05	1139	153	16	36417873
Pubmed	Assembly and Function of Heterotypic Ubiquitin Chains in Cell-Cycle and Protein Quality Control.	UBR4 UBR5 ANAPC1	5.43e-05	17	153	3	29033132
Pubmed	Maturational disturbance of chondrocytes in Cbfa1-deficient mice.	COL2A1 COL5A1 COL11A2	5.43e-05	17	153	3	10213384
Pubmed	KAP1 regulates type I interferon/STAT1-mediated IRF-1 gene expression.	STAT1 TRIM28	5.75e-05	3	153	2	18381204
Pubmed	Febrile infection-related epilepsy syndrome (FIRES) is not caused by SCN1A, POLG, PCDH19 mutations or rare copy number variations.	POLG SCN1A	5.75e-05	3	153	2	23066759
Pubmed	SCN1A, ABCC2 and UGT2B7 gene polymorphisms in association with individualized oxcarbazepine therapy.	SCN1A ABCC2	5.75e-05	3	153	2	25823783
Pubmed	Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+).	SCN1A SCN3A	5.75e-05	3	153	2	33895391
Pubmed	Associations of genetic polymorphisms of the transporters organic cation transporter 2 (OCT2), multidrug and toxin extrusion 1 (MATE1), and ATP-binding cassette subfamily C member 2 (ABCC2) with platinum-based chemotherapy response and toxicity in non-small cell lung cancer patients.	SLC47A1 ABCC2	5.75e-05	3	153	2	27590272
Pubmed	The role of Tyk2, Stat1 and Stat4 in LPS-induced endotoxin signals.	STAT1 TYK2	5.75e-05	3	153	2	15226272
Pubmed	SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.	SCN1A SCN3A	5.75e-05	3	153	2	23859570
Pubmed	Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock.	STAT1 TYK2	5.75e-05	3	153	2	12679810
Pubmed	Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma.	STAT1 TYK2	5.75e-05	3	153	2	30131584
Pubmed	Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.	ERVK-6 ERVK-9	5.75e-05	3	153	2	9971820
Pubmed	GAPDH-mediated posttranscriptional regulations of sodium channel Scn1a and Scn3a genes under seizure and ketogenic diet conditions.	SCN1A SCN3A	5.75e-05	3	153	2	27816501
Pubmed	Respiratory syncytial virus impairs macrophage IFN-alpha/beta- and IFN-gamma-stimulated transcription by distinct mechanisms.	STAT1 TYK2	5.75e-05	3	153	2	19502390
Pubmed	Pro-alpha3(V) collagen chain is expressed in bone and its basic N-terminal peptide adheres to osteosarcoma cells.	COL2A1 COL5A1	5.75e-05	3	153	2	15908193
Pubmed	Col11a1 and Col11a2 mRNA expression in the developing mouse cochlea: implications for the correlation of hearing loss phenotype with mutant type XI collagen genotype.	COL2A1 COL11A2	5.75e-05	3	153	2	15141750
Pubmed	The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction.	STAT1 TYK2	5.75e-05	3	153	2	8232552
Pubmed	TYK2-STAT1-BCL2 pathway dependence in T-cell acute lymphoblastic leukemia.	STAT1 TYK2	5.75e-05	3	153	2	23471820
Pubmed	The Association of Variants within Types V and XI Collagen Genes with Knee Joint Laxity Measurements.	COL5A1 COL11A2	5.75e-05	3	153	2	36553626
Pubmed	UBR E3 ligases and the PDIA3 protease control degradation of unfolded antibody heavy chain by ERAD.	UBR4 UBR5	5.75e-05	3	153	2	32558906
Pubmed	Sodium channels SCN1A, SCN2A and SCN3A in familial autism.	SCN1A SCN3A	5.75e-05	3	153	2	12610651
Pubmed	An IFNγ/STAT1/JMJD3 Axis Induces ZEB1 Expression and Promotes Aggressiveness in Lung Adenocarcinoma.	KDM6B STAT1	5.75e-05	3	153	2	33771881
Pubmed	A comprehensive study of the spatial and temporal expression of the col5a1 gene in mouse embryos: a clue for understanding collagen V function in developing connective tissues.	COL2A1 COL5A1	5.75e-05	3	153	2	17024418
Pubmed	Tyrosine kinase 2 controls IL-1ß production at the translational level.	STAT1 TYK2	5.75e-05	3	153	2	20713887
Pubmed	Human endogenous retrovirus protein Rec interacts with the testicular zinc-finger protein and androgen receptor.	ERVK-6 ZBTB32	5.75e-05	3	153	2	20147518
Pubmed	KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response.	CHD3 TRIM28	5.75e-05	3	153	2	21642969
Pubmed	Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.	SCN1A SCN3A	5.75e-05	3	153	2	18784617
Pubmed	Association Between COL5a1, COL11a1, and COL11a2 Gene Variations and Rotator Cuff Tendinopathy in Young Athletes.	COL5A1 COL11A2	5.75e-05	3	153	2	34009784
Pubmed	Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.	ERVK-6 ERVK-19	5.75e-05	3	153	2	10516026
Pubmed	Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.	SCN1A SCN3A	5.75e-05	3	153	2	17544618
Pubmed	Oligomerization of transcriptional intermediary factor 1 regulators and interaction with ZNF74 nuclear matrix protein revealed by bioluminescence resonance energy transfer in living cells.	TRIM28 ZNF74	5.75e-05	3	153	2	12684500
Pubmed	The SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFN-alpha signals.	STAT1 TYK2	5.75e-05	3	153	2	8605877
Pubmed	Age-related deregulation of Aire and peripheral tissue antigen genes in the thymic stroma of non-obese diabetic (NOD) mice is associated with autoimmune type 1 diabetes mellitus (DM-1).	COL2A1 AIRE	5.75e-05	3	153	2	20414703
Pubmed	Association of SCN1A, SCN2A and ABCC2 gene polymorphisms with the response to antiepileptic drugs in Chinese Han patients with epilepsy.	SCN1A ABCC2	5.75e-05	3	153	2	25155934
Pubmed	Collagen binding specificity of the discoidin domain receptors: binding sites on collagens II and III and molecular determinants for collagen IV recognition by DDR1.	COL2A1 DDR1	5.75e-05	3	153	2	21044884
Pubmed	TRIM28 regulates the nuclear accumulation and toxicity of both alpha-synuclein and tau.	TRIM28 SNCA	5.75e-05	3	153	2	27779468
Pubmed	Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.	SCN1A SCN3A	5.75e-05	3	153	2	14973256
Pubmed	Store-independent activation of Orai1 by SPCA2 in mammary tumors.	ATP2C1 ATP2C2	5.75e-05	3	153	2	20887894
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	PABIR1 TFEB TOM1 PPIL4 APBA3 FAM98B RAB11FIP1 BLZF1 STAT1 GPALPP1 UBR5 MTREX LAS1L TRIM37 ACAP3	5.78e-05	1038	153	15	26673895
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	TFEB FLYWCH1 ARID4A MECOM CHD3 ZBTB7B PWWP2A NCOR2 ANAPC1 TRIM28 AHNAK ANKRD11 PRPF19 MTREX LAS1L ZMYM3 RAI1	5.94e-05	1294	153	17	30804502
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	TFEB SETD1B MAP1A MECOM NCOR2 UBR5 ANAPC1 MTREX SIPA1L2 TRIM37 ZMYM3	6.31e-05	588	153	11	38580884
Pubmed	LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.	PCDHGA10 CC2D1B NCOR2 ANKRD11 PALM3 PHACTR1	1.04e-04	168	153	6	30631154
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	UBR4 MECOM CHD3 NCOR2 UBR5 ANAPC1 AHNAK CAMSAP1 ZMYM3	1.04e-04	418	153	9	34709266
Pubmed	Corepressor SMRT is required to maintain Hox transcriptional memory during somitogenesis.	UNCX KDM6B NCOR2	1.05e-04	21	153	3	30254164
Pubmed	Stat2 loss leads to cytokine-independent, cell-mediated lethality in LPS-induced sepsis.	STAT1 TYK2	1.15e-04	4	153	2	23653476
Pubmed	Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.	SCN1A SCN3A	1.15e-04	4	153	2	17537961
Pubmed	A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons.	UBR4 UBR5	1.15e-04	4	153	2	16055722
Pubmed	The signal transducers Stat1 and Stat3 and their novel target Jmjd3 drive the expression of inflammatory genes in microglia.	KDM6B STAT1	1.15e-04	4	153	2	24097101
Pubmed	Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau.	TRIM28 SNCA	1.15e-04	4	153	2	29863470
Pubmed	Re-examination of the role of suppressor of cytokine signaling 1 (SOCS1) in the regulation of toll-like receptor signaling.	STAT1 TYK2	1.15e-04	4	153	2	15491990
Pubmed	Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.	SCN1A SCN3A	1.15e-04	4	153	2	35801810
Pubmed	The rab11 effector protein FIP1 regulates adiponectin trafficking and secretion.	RAB11FIP1 RAB11FIP3	1.15e-04	4	153	2	24040321
Pubmed	PHD domain-mediated E3 ligase activity directs intramolecular sumoylation of an adjacent bromodomain required for gene silencing.	CHD3 TRIM28	1.15e-04	4	153	2	18082607
Cytoband	15q13.2	GOLGA8T GOLGA8Q GOLGA8N	4.53e-05	21	152	3	15q13.2
Cytoband	11p15	APBB1 IRAG1 NLRP6	3.98e-04	43	152	3	11p15
Cytoband	9q34.3	LINC02908 AJM1 SOHLH1 CAMSAP1	4.41e-04	106	152	4	9q34.3
Cytoband	Ensembl 112 genes in cytogenetic band chr9q34	COL5A1 SPTAN1 LINC02908 AJM1 SOHLH1 CAMSAP1	7.84e-04	325	152	6	chr9q34
GeneFamily	Collagens	COL2A1 COL5A1 COL11A2 COL15A1	8.34e-05	46	91	4	490
GeneFamily	Ubiquitin protein ligase E3 component n-recognins	UBR4 UBR5	5.18e-04	7	91	2	785
GeneFamily	ATPases Ca2+ transporting	ATP2C1 ATP2C2	8.82e-04	9	91	2	1209
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN1A SCN3A	8.82e-04	9	91	2	1203
GeneFamily	PDZ domain containing	APBA3 CYTIP AHNAK SIPA1L2 PDZD2	1.02e-03	152	91	5	1220
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	TRIO SPTAN1 BLZF1 SLC4A3 POLR3A NCOR2 PTPRF MTREX CAMSAP1 ZNF282	1.18e-09	200	145	10	1fa8422fd820d21e285a7e7c4c6fbd8b7277d2af
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NIBAN1 ARHGAP30 CCDC88B RTN1 FCHO1 FMNL3 PIK3R6 FYB1	2.39e-07	193	145	8	3e3d7cb3e7242ec9c9677e07e303835649852b52
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TFEB NIBAN1 RNF149 KDM6B CYTIP KLF2 FYB1 PHACTR1	2.49e-07	194	145	8	607b5d194ba56efa9b106f10f89368fc103712a0
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TFEB NIBAN1 RNF149 KDM6B CYTIP KLF2 FYB1 PHACTR1	2.49e-07	194	145	8	f5367072b259ae170cf0df3d4d871ab41be29d29
ToppCell	facs-Marrow-B-cells-18m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDR1 TOM1 TMED3 PTPRF AHNAK ARHGAP27 FYB1	2.20e-06	181	145	7	e6c78038b14100e0c9c6fe25e8f0b75c02c33549
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNCX RTN1 KCNH2 SCN1A SLC17A7 CACNA1I SNCA	2.54e-06	185	145	7	70de48988c1f8e0809afc8092b663aa439d8e528
ToppCell	Control-Epithelial_cells\|Control / group, cell type (main and fine annotations)	MECOM NR6A1 RAB11FIP1 SCN1A ATP2C2 PDZD2 PHACTR1	2.82e-06	188	145	7	707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	NIBAN1 RNF149 KDM6B CYTIP KLF2 FYB1 PHACTR1	3.47e-06	194	145	7	b04cbd240c59755ef7bdeb17fee3028caef6dedb
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NIBAN1 ARHGAP30 CCDC88B RTN1 FCHO1 PIK3R6 FYB1	3.47e-06	194	145	7	badefcec2af86cbcd97305f4843e84db0f3ebc66
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	NIBAN1 RNF149 KDM6B CYTIP KLF2 FYB1 PHACTR1	3.47e-06	194	145	7	744fd4580942183a1058717d0c3ac86483e366ed
ToppCell	COVID-19_Severe-Neu_0\|COVID-19_Severe / 5 Neutrophil clusters in COVID-19 patients	NIBAN1 RNF149 RAB11FIP1 KLF2 FYB1 PLK3 PHACTR1	3.72e-06	196	145	7	4831243fcd680cf4821fa0246e758c3e7c13a962
ToppCell	COVID-19_Severe-Neu_0\|World / 5 Neutrophil clusters in COVID-19 patients	NIBAN1 RNF149 RAB11FIP1 KLF2 FYB1 PLK3 PHACTR1	3.72e-06	196	145	7	4fdea41ac7d84f0c52d102d87a5fce620480985e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NIBAN1 ARHGAP30 CCDC88B RTN1 CYTIP PIK3R6 FYB1	3.72e-06	196	145	7	291c59b609985167c98a40d4e2caeea2fad74941
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NIBAN1 RNF149 KDM6B CYTIP KLF2 FYB1 PHACTR1	3.84e-06	197	145	7	340ce4fef244176fb52e38ffbcbdfda5ac3467dd
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NIBAN1 ARHGAP30 CCDC88B RTN1 LINC02908 PIK3R6 FYB1	3.84e-06	197	145	7	826cc6baafab13e7ef5cfcf28cd79d0fbf3af38d
ToppCell	facs-MAT-Fat-3m-Epithelial-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL11A2 IRAG1 NLRP6 ATP2C2 SNCA	1.34e-05	93	145	5	dbfaa7f23d25f5c286ab7ca3ca795b734cb95153
ToppCell	facs-MAT-Fat-3m-Epithelial-epithelial_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL11A2 IRAG1 NLRP6 ATP2C2 SNCA	1.34e-05	93	145	5	0d6d1d8dd9c91ba31eb35a4b5979d087890936c1
ToppCell	facs-MAT-Fat-3m-Epithelial\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL11A2 IRAG1 NLRP6 ATP2C2 SNCA	1.34e-05	93	145	5	abffb1fd5a919b7c08e62e1c3c08a8dd8783a4ca
ToppCell	frontal_cortex-Non-neuronal-endothelial_cell\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NES XDH MECOM RAB11FIP1 KLF2 AHNAK	1.64e-05	164	145	6	6a41a159134e605b80d5e731f9ed5bc803bb531b
ToppCell	droplet-Lung-21m-Hematologic-myeloid-intermediate_monocyte\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TFEB NIBAN1 RNF149 CYTIP SLC17A7 FYB1	1.64e-05	164	145	6	cd0794f84dfd346807e2d803723718b7f22e9232
ToppCell	droplet-Lung-21m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TFEB NIBAN1 RNF149 CYTIP SLC17A7 FYB1	1.64e-05	164	145	6	12251a49fd4af32d4edb58046245548c260cf04b
ToppCell	frontal_cortex-Non-neuronal-endothelial_cell-Endo\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NES XDH MECOM RAB11FIP1 KLF2 AHNAK	1.64e-05	164	145	6	ec68954fc09b6850273b5e59caa6b09d02151097
ToppCell	frontal_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NES XDH MECOM RAB11FIP1 KLF2 AHNAK	1.75e-05	166	145	6	27af6c906cff1d40d134f0386db7708869691121
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NIBAN1 MAP1A RNF149 IRAG1 TNXB PLXNA1	1.81e-05	167	145	6	784776d1fcc098f84d3c2eca58fa56cb9428f434
ToppCell	droplet-Thymus-nan-18m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD3 ZBTB7B STAT1 CYTIP KLF2 FYB1	2.01e-05	170	145	6	90f7640f04672c800cb28aea50004b1bb0565e8a
ToppCell	3'_v3-bone_marrow-Mast-Mast_cell_lympho\|bone_marrow / Manually curated celltypes from each tissue	COL5A1 LURAP1 MAP1A TRIO LINC02908 KCNH2	2.01e-05	170	145	6	4dedf482cd4521b3f87d2b5ae80f7a3ea8686a15
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD4_INF-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NIBAN1 CYTIP KLF2 AHNAK N4BP1 FYB1	2.07e-05	171	145	6	e6dfbd2652b67577c8834c05348f62150637f348
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD4_INF\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NIBAN1 CYTIP KLF2 AHNAK N4BP1 FYB1	2.07e-05	171	145	6	ddaeb96ce9c9c3bf232b4a42266fa2ee7e8f3f41
ToppCell	droplet-Thymus-nan-18m-Lymphocytic-DN4\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD3 ZBTB7B STAT1 CYTIP KLF2 FYB1	2.07e-05	171	145	6	f08402d0f42822c35673522043b652f8fb68d2f6
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Plasmacytoid_Dendritic_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MAP1A RAB11FIP1 CCDC88B FCHO1 FMNL3 LINC02908	2.07e-05	171	145	6	af1c93eb75f45c042ea475d93db56e4da207e31f
ToppCell	facs-Marrow-T-cells-24m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDR1 LRRC74A PTPRF AHNAK ARHGAP27 FYB1	2.21e-05	173	145	6	ca3d2a9562734f76127e3e7d54c10b63e95141bb
ToppCell	facs-Marrow-T-cells-24m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDR1 LRRC74A PTPRF AHNAK ARHGAP27 FYB1	2.21e-05	173	145	6	19a9e10885173d7712996be8660a3a5a7a9aa39f
ToppCell	P03-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DDR1 APBB1 RAB11FIP1 PTPRF AHNAK PHACTR1	2.44e-05	176	145	6	f3a54038cde58326f1caed96ecca33c141bcc8b3
ToppCell	3'-Adult-LargeIntestine-Hematopoietic-T_cells-Treg\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	APBB1 ARHGAP30 CYTIP ZBTB32 CACNA1I FYB1	2.60e-05	178	145	6	307b6e21bc69a0310c550f1fafa8600285e99ccd
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	TFEB COL15A1 SETD1B PALM3 PRPF19	2.65e-05	107	145	5	410b37beffaf637a2a64c9d0ce7baf81f4bc667c
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	TFEB COL15A1 SETD1B PALM3 PRPF19	2.65e-05	107	145	5	5bae4b3aede9bcbf7e88414e3453973cc8b0c3e7
ToppCell	COVID-19-Epithelial_cells-AT1\|COVID-19 / group, cell type (main and fine annotations)	MECOM NR6A1 RAB11FIP1 PTPRF PDZD2 PHACTR1	2.68e-05	179	145	6	a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL2A1 NES LURAP1 ANGEL1 NCOR2 SLC47A1	2.77e-05	180	145	6	c72f15763ba707189e29c85db533557f01c7fdb1
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNCX AKAIN1 CCDC88B RTN1 CYTIP SLC17A7	2.77e-05	180	145	6	6ac62bf1251978c8c12e715f7b73144fca619794
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NES COL15A1 MAP1A IRAG1 PIK3R6 KCNH2	2.77e-05	180	145	6	79c5725f02e038d0187f4a1e1591f2492538aa57
ToppCell	control-Lymphoid-B_cell\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	FMNL3 ZBTB32 LINC02908 PIK3R6 SCN3A PHACTR1	2.85e-05	181	145	6	e414303bb90e5fe7b667c2acf9a50f8694b90e54
ToppCell	PCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_B-im_B_cell_(15)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	AIRE ARHGAP30 FCHO1 CYTIP SCN3A ARHGAP27	2.85e-05	181	145	6	51e4d6bfdbf414d8e30aee2e6f7492f4f7f54373
ToppCell	NS-control-d_0-4-Lymphoid-B_cell\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FMNL3 ZBTB32 LINC02908 PIK3R6 SCN3A PHACTR1	2.94e-05	182	145	6	4b9b55154a79992112c1c467e8752c3cdbb541d9
ToppCell	Cerebellum-Macroglia\|Cerebellum / BrainAtlas - Mouse McCarroll V32	COL2A1 TMEM52 DDR1 COL11A2 GJC2 TSC22D4	3.13e-05	184	145	6	91b047a01d2cad231308279ca37fa699630f7864
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNCX AKAIN1 RTN1 KCNH2 SCN1A SLC17A7	3.13e-05	184	145	6	7d9bcdaff8cbea4c50ab7db0f8e01f6bbd0ef593
ToppCell	P15-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DDR1 APBB1 MECOM RAB11FIP1 PTPRF AHNAK	3.33e-05	186	145	6	521e6e007bbae73e7328153aa170cf04ca3c1093
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNCX RTN1 SCN1A SLC17A7 CACNA1I SNCA	3.43e-05	187	145	6	7b2cd0c618ed081223343f3bec2244c8723c9a31
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNCX AKAIN1 RTN1 KCNH2 SCN1A SLC17A7	3.53e-05	188	145	6	1efbc99bcd6542e5d9fa91edb7c4295167914786
ToppCell	COVID-19-Epithelial_cells\|COVID-19 / group, cell type (main and fine annotations)	MECOM NR6A1 RAB11FIP1 PTPRF ATP2C2 PDZD2	3.53e-05	188	145	6	c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL5A1 NIBAN1 TRIO TMED3 SCN3A TNXB	3.75e-05	190	145	6	947807863a9b247c301c6cf63d6fd5a2c8018e66
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Monocytic-Classical_Monocyte-Mono_c1-CD14-CCL3\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NIBAN1 KDM6B KLF2 FYB1 PLK3 PHACTR1	3.75e-05	190	145	6	212f0d9defcc3174e225cc3d90e7814e238794b6
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL5A1 NIBAN1 TRIO TMED3 SCN3A TNXB	3.86e-05	191	145	6	db4943dd19207663fb9e27f8940fa4b06a933625
ToppCell	NS-moderate-d_16-33-Myeloid-Neutrophil\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NIBAN1 RNF149 KDM6B KLF2 FYB1 PHACTR1	3.97e-05	192	145	6	545c3990cbe3c04bfd95a0ab7499d2c4af509be1
ToppCell	NS-critical-d_0-4-Myeloid-Neutrophil\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NIBAN1 RNF149 KDM6B KLF2 FYB1 PHACTR1	3.97e-05	192	145	6	3db74359c30172a51177e00eac1f48f483e15578
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-T_follicular_helper_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RNF149 KDM6B ITPKB NLRP6 TRIM28 PLK3	3.97e-05	192	145	6	3e2a0f332e7f9833ba88f3c809cee78b65090401
ToppCell	moderate-Myeloid-Neutrophil\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	NIBAN1 RNF149 KDM6B KLF2 FYB1 PHACTR1	3.97e-05	192	145	6	8105408400dac5dcb0ce62b558433257559c9f09
ToppCell	moderate-Lymphoid-B_cell\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TFEB KDM6B KLF2 ZBTB32 SCN3A PHACTR1	3.97e-05	192	145	6	ae3727503c3b9f4695e565fd3161cc33b898f349
ToppCell	COVID-19_Severe-Classical_Monocyte-cMono_2\|Classical_Monocyte / Disease condition and Cell class	MAP1A RNF149 KDM6B RTN1 FKBP8 SNCA	4.09e-05	193	145	6	add29b6abdfa49c7f0a0f49841a588d03e3bdb48
ToppCell	18-Distal-Mesenchymal-Cartilage\|Distal / Age, Tissue, Lineage and Cell class	COL2A1 COL11A2 COL15A1 MECOM ALX4 TSC22D4	4.09e-05	193	145	6	52f3d1bb8d8ca91ba12439d46392f377928ff8f8
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NIBAN1 RNF149 ARHGAP30 RTN1 CYTIP FYB1	4.21e-05	194	145	6	96f16bcd393a0d3f8df479b172b5360ae5a1e663
ToppCell	facs-Bladder-nan-3m-Epithelial-bladder_urothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MECOM IRF6 RAB11FIP1 PTPRF MAPKAPK3 SYTL1	4.21e-05	194	145	6	1531dcace28a14bd700e909a027426a8cee20337
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NIBAN1 RNF149 KDM6B KLF2 FYB1 PHACTR1	4.21e-05	194	145	6	4eef50c38e6edb2ef2cdcd14eb50805f6cd65bc8
ToppCell	COVID-19-lung-NK_cells\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TSEN54 ARHGAP30 CCDC88B CYTIP SYTL1 FYB1	4.21e-05	194	145	6	4c92f18e0a34fb50630d4b260eaf179202508b6d
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|390C / Donor, Lineage, Cell class and subclass (all cells)	PTPRF UBR5 ATP2C2 ARHGAP27 TRIM37 RAB11FIP3	4.21e-05	194	145	6	88db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	PTPRF UBR5 ATP2C2 ARHGAP27 TRIM37 RAB11FIP3	4.21e-05	194	145	6	a71728202493d4858342ea2756ea281cd0d99a3a
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	NIBAN1 KDM6B CYTIP KLF2 FYB1 PHACTR1	4.21e-05	194	145	6	d2f6c8900b5c448eede8047ca964e94b19bd6ca5
ToppCell	Control-B_memory-3\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TFEB NIBAN1 VSIG1 LINC02908 PIK3R6 AHNAK	4.33e-05	195	145	6	135234f068da3e8db7213b53c09ed6d1d0cdc351
ToppCell	nucseq-Epithelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MECOM NR6A1 PTPRF ATP2C2 PDZD2 PHACTR1	4.33e-05	195	145	6	9406866f99555198a9be311fbd65751b70f35446
ToppCell	droplet-Tongue\|droplet / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDR1 IRF6 PTPRF MAPKAPK3 SYTL1 GOT2	4.33e-05	195	145	6	e460b09ae354b579ce552acebdaa5877a6e62343
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NIBAN1 KDM6B CYTIP KLF2 FYB1 PHACTR1	4.45e-05	196	145	6	6230b4a26770d30f1ab83345c087f03be1be0f9e
ToppCell	control-Others-Megakaryocytes\|Others / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	NIBAN1 RNF149 ARHGAP30 RAB11FIP1 KLF2 FYB1	4.45e-05	196	145	6	10d914f1612622f64ac71da04e1995a854a4bec9
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL5A1 NES TRIO NCOR2 PLXNA1 ACAP3	4.45e-05	196	145	6	b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCell	3'-Adult-LargeIntestine-Hematopoietic-B_cells-Memory_B\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TFEB ARHGAP30 CYTIP KLF2 ZBTB32 PHACTR1	4.45e-05	196	145	6	c7363794fb731848e4343b3a4e4f800f9c81999a
ToppCell	PND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DDR1 APBB1 RAB11FIP1 PTPRF AHNAK PHACTR1	4.45e-05	196	145	6	9790340c25f446ec655f5a0b64ec3bb44ed2e1bd
ToppCell	PND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DDR1 APBB1 RAB11FIP1 PTPRF AHNAK PHACTR1	4.45e-05	196	145	6	b9ceceeacbcf81976ce92adf044f0d0aa132632b
ToppCell	15-Trachea\|15 / Age, Tissue, Lineage and Cell class	DDR1 IRF6 RAB11FIP1 PTPRF ATP2C2 SYTL1	4.45e-05	196	145	6	fd17403422cf95c24f6be1c2d78764bb352f7f2e
ToppCell	Monocytes-cDCs\|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis	NIBAN1 RAB11FIP1 SLC4A3 RTN1 FCHO1 PHACTR1	4.58e-05	197	145	6	15cb9fe1c3bab80bd24728fd9ac7ba385912ac33
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NIBAN1 ARHGAP30 CCDC88B RTN1 CYTIP FYB1	4.58e-05	197	145	6	0523aec9713ae21e6b879aa98e07fa2576610d5f
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	NIBAN1 SPTAN1 CD320 ZBTB32 SYTL1 ZNF282	4.58e-05	197	145	6	7c9df6025b9d168bd6d041c6cff1e87e08b11847
ToppCell	critical-Myeloid-Neutrophil\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	NIBAN1 RNF149 KDM6B KLF2 FYB1 PHACTR1	4.58e-05	197	145	6	f1248781e71e3a158d06e9ec93eb90dc6d48bcb2
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NIBAN1 RNF149 KDM6B KLF2 FYB1 PHACTR1	4.58e-05	197	145	6	3cd1c816bc7a57278b2ef615b69545356ab8f522
ToppCell	(2)_Fibroblasts-(24)_Fibro-5\|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis	COL5A1 COL15A1 APBB1 KLF2 AHNAK TNXB	4.58e-05	197	145	6	83a4b79fbfa1cf63441dee4424c3b87c988287bf
ToppCell	NS-critical-d_07-13-Myeloid-Neutrophil\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NIBAN1 RNF149 KDM6B KLF2 FYB1 PHACTR1	4.58e-05	197	145	6	f38037dfa6c33e9336130d0cc65eaba0f120efb9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP30 CCDC88B RTN1 FCHO1 CYTIP FYB1	4.58e-05	197	145	6	72cd61b868d57862ec9c230ea68913d3829b0f2b
ToppCell	wk_20-22\|World / Celltypes from embryonic and fetal-stage human lung	ARHGAP30 CYTIP KLF2 ARHGAP27 SYTL1 FYB1	4.71e-05	198	145	6	56eb765773a1a27a44262a447df7cfae8a9db90d
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL2A1 COL5A1 COL11A2 COL15A1 TMED3 TNXB	4.71e-05	198	145	6	1b90d632e59c3c47b936e829cceeb0334f05f34f
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4\|lymph-node_spleen / Manually curated celltypes from each tissue	APBB1 CHD3 CYTIP ITPKB FYB1 PLK3	4.71e-05	198	145	6	2cbafcb03df3c9aca68371df500d18ab8dcc416c
ToppCell	critical-Myeloid-Neutrophil\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	NIBAN1 RNF149 KDM6B KLF2 FYB1 PHACTR1	4.71e-05	198	145	6	4da73dc3acb29d70b160903600d2bf7fdab34333
ToppCell	severe-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	NIBAN1 RNF149 RAB11FIP1 KDM6B PLK3 PHACTR1	4.71e-05	198	145	6	d5e525d2f2226d06a3fb985ce3a33555ff4b2e7b
ToppCell	Epithelial_cells-AT1-AT2_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	ARID4A SPTAN1 RAB11FIP1 AHNAK N4BP1 PLXNA1	4.71e-05	198	145	6	fbc46b20bcd44f2083170aacbc6f5dd00fba685c
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MECOM NR6A1 SCN1A ATP2C2 PDZD2 PHACTR1	4.85e-05	199	145	6	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MECOM NR6A1 SCN1A ATP2C2 PDZD2 PHACTR1	4.85e-05	199	145	6	8587bd98de7767a575088afbea07a1feb4516b9b
ToppCell	21-Trachea-Epithelial\|Trachea / Age, Tissue, Lineage and Cell class	DDR1 IRF6 RAB11FIP1 PTPRF AHNAK ATP2C2	4.85e-05	199	145	6	8eb8b086c38960200578a9fe8853ca6e894ddee4
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KLHL1 RTN1 TMEM132C SCN1A ATP2C2 PDZD2	4.85e-05	199	145	6	333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KLHL1 RTN1 TMEM132C SCN1A ATP2C2 PDZD2	4.85e-05	199	145	6	e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCell	(1)_T_cell-(12)_Th1\|(1)_T_cell / shred on Cell_type and subtype	NIBAN1 MAP1A RAB11FIP1 KDM6B AHNAK PLK3	4.85e-05	199	145	6	15133e0a4ea6cfcc27c1d438d9e854879ea84c30
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_\|World / Primary Cells by Cluster	ARID4A SPTAN1 CHD3 RTN1 SCN3A SNCA	4.85e-05	199	145	6	058373b4ac3cec2108cb24265628ff0a50646e33
ToppCell	NS-moderate-d_0-4-Epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DDR1 MECOM RAB11FIP1 PTPRF AHNAK ATP2C2	4.98e-05	200	145	6	64462a18afca3c1a8548a857924b8166058bf958
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuroepithelial\|10w / Sample Type, Dataset, Time_group, and Cell type.	COL5A1 IRF6 TSEN54 ITPKB TMEM132C AHNAK	4.98e-05	200	145	6	ff0b2675c68e9fc1fa16b3276431f199f3642eac
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuroepithelial-Proteoglycan-expressing_cell\|10w / Sample Type, Dataset, Time_group, and Cell type.	COL5A1 IRF6 TSEN54 ITPKB TMEM132C AHNAK	4.98e-05	200	145	6	07d2133c85e0a4eb8bef653ee15ecd0f1b2bbd44
Drug	Sanguinarine [2447-54-3]; Down 200; 12uM; MCF7; HT_HG-U133A	COL5A1 POLG UBR4 IRF6 CHD3 PTPRF UBR5 AHNAK BRWD1	3.66e-06	191	144	9	4168_DN
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A	RTEL1 RRAGB NR6A1 SLC4A3 CEP68 TESMIN CACNA1I CAMSAP1 PLK3	4.15e-06	194	144	9	5914_DN
Drug	Phensuximide [86-34-0]; Up 200; 21.2uM; PC3; HT_HG-U133A	COL5A1 SETD1B RTEL1 SPTAN1 TOM1 APBA3 XDH BRWD1 RAB11FIP3	4.52e-06	196	144	9	5097_UP
Drug	Furosemide [54-31-9]; Down 200; 12uM; PC3; HT_HG-U133A	TFEB MAP1A RTEL1 SLC4A3 AHNAK CACNA1I FKBP8 SNCA PLK3	4.71e-06	197	144	9	4503_DN
Drug	Neostigmine bromide [114-80-7]; Down 200; 13.2uM; MCF7; HT_HG-U133A	NES SETD1B SPTAN1 APBA3 CHD3 BLZF1 BAHD1 PLXNA1 ZMYM3	4.91e-06	198	144	9	5335_DN
Drug	Althiazide [5588-16-9]; Down 200; 10.4uM; MCF7; HT_HG-U133A	SPTAN1 TOM1 RRAGB ITPKB KCNH2 FKBP8 SNCA CAMSAP1 PLK3	5.32e-06	200	144	9	6829_DN
Drug	Primaquine diphosphate [63-45-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A	TRIO CHD3 PSME4 PTPRF UBR5 ANKRD11 ZMYM3 BRWD1	2.69e-05	188	144	8	4845_DN
Drug	Budesonide [51333-22-3]; Up 200; 9.2uM; PC3; HT_HG-U133A	COL2A1 COL15A1 XDH KDM6B CEP68 NCOR2 SNCA PLK3	3.49e-05	195	144	8	6330_UP
Drug	Methoxy-6-harmalan [3589-73-9]; Down 200; 18.6uM; HL60; HG-U133A	ANGEL1 KDM6B ATP2C1 ANKRD11 N4BP1 FKBP8 CAMSAP1 PLXNA1	3.49e-05	195	144	8	1743_DN
Drug	Alfadolone acetate [23930-37-2]; Down 200; 10.2uM; HL60; HT_HG-U133A	PCDHGA10 SPTAN1 CD320 CEP68 PHKG2 ABCC2 PLK3 RAB11FIP3	3.76e-05	197	144	8	3127_DN
Drug	Carcinine [56897-53-1]; Up 200; 22uM; HL60; HT_HG-U133A	TFEB CHD3 BAHD1 CEP68 N4BP1 TSC22D4 SNCA PLXNA1	3.76e-05	197	144	8	1305_UP
Drug	Zimelidine dihydrochloride monohydrate [61129-30-4]; Down 200; 9.8uM; HL60; HG-U133A	ANGEL1 KRI1 APBA3 IRGQ RAB11FIP1 AHNAK N4BP1 PLXNA1	3.76e-05	197	144	8	2012_DN
Drug	Mefenamic acid [61-68-7]; Down 200; 16.6uM; HL60; HT_HG-U133A	COL15A1 POLG SPTAN1 CD320 BAHD1 STAT1 FKBP8 ZMYM3	3.76e-05	197	144	8	1863_DN
Drug	Beta-sistosterol [83-46-5]; Down 200; 9.6uM; HL60; HT_HG-U133A	KRI1 RRAGB BAHD1 ITPKB AHNAK FKBP8 TSC22D4 PLXNA1	3.76e-05	197	144	8	2912_DN
Drug	Chlorogenic acid [327-97-9]; Down 200; 11.2uM; PC3; HT_HG-U133A	TFEB MAP1A SPTAN1 MECOM ATP2C2 SLC17A7 CACNA1I N4BP1	3.76e-05	197	144	8	4024_DN
Drug	Meclofenoxate hydrochloride [3685-84-5]; Up 200; 13.6uM; MCF7; HT_HG-U133A	TRIO SPTAN1 KCNH2 SLC17A7 CACNA1I FKBP8 CAMSAP1 BRWD1	3.89e-05	198	144	8	3405_UP
Drug	Tribenoside [10310-32-4]; Up 200; 8.4uM; MCF7; HT_HG-U133A	RTEL1 SPTAN1 MECOM AHNAK SLC47A1 ZNF282 PLK3 PDZD2	3.89e-05	198	144	8	5429_UP
Drug	cis-4,7,10,13,16,19-Docosahexaenoic acid ethyl ester; Down 200; 100uM; PC3; HG-U133A	KLHL1 RTEL1 TOM1 KRI1 APBA3 MECOM KCNH2 RAB11FIP3	3.89e-05	198	144	8	664_DN
Drug	Cinoxacin [28657-80-9]; Up 200; 15.2uM; MCF7; HT_HG-U133A	COL5A1 SETD1B SPTAN1 TOM1 CHD3 KCNH2 FKBP8 SNCA	3.89e-05	198	144	8	6257_UP
Drug	Amantadine	STAT1 KCNH2 SLC47A1	3.94e-05	11	144	3	ctd:D000547
Drug	Nitrocaramiphen hydrochloride; Down 200; 10.8uM; HL60; HT_HG-U133A	PCDHGA10 KRI1 KDM6B N4BP1 FKBP8 ABCC2 CAMSAP1 RAB11FIP3	4.04e-05	199	144	8	3125_DN
Drug	Diphenylpyraline hydrochloride [132-18-3]; Down 200; 12.6uM; MCF7; HT_HG-U133A	RTEL1 SPTAN1 BLZF1 CEP68 FKBP8 ABCC2 CAMSAP1 BRWD1	4.04e-05	199	144	8	4765_DN
Drug	Ketoprofen [22071-15-4]; Up 200; 15.8uM; HL60; HT_HG-U133A	ANGEL1 XDH NR6A1 AHNAK SLC17A7 FKBP8 SNCA CAMSAP1	4.04e-05	199	144	8	2354_UP
Drug	Condelphine [7633-69-4]; Up 200; 8.8uM; MCF7; HT_HG-U133A	TRIO AIRE MECOM KLF2 AHNAK CACNA1I ABCC2 PLK3	4.18e-05	200	144	8	3538_UP
Drug	lariat	COL5A1 DDR1 ANGEL1 MECOM SCN3A PRPF19	5.55e-05	105	144	6	CID000165706
Drug	NSC172219	XDH GOT2	1.19e-04	3	144	2	CID000425265
Drug	N-desmethylmethsuximide	CACNA1I TRIM37	1.19e-04	3	144	2	CID000092154
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A	MAP1A IRF6 NR6A1 RAB11FIP1 STAT1 KCNH2 SLC17A7	1.52e-04	180	144	7	4344_UP
Drug	Zonisamide	SCN1A SCN3A CACNA1I	1.58e-04	17	144	3	DB00909
Drug	trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A	SPTAN1 IRF6 RAB11FIP1 STAT1 CEP68 PHKG2 PLK3	1.63e-04	182	144	7	7503_UP
Drug	trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A	SPTAN1 XDH IRF6 RAB11FIP1 CEP68 SLC17A7 PLK3	1.68e-04	183	144	7	6874_UP
Drug	nevirapine	ERVK-6 POLG FYB1 GOT2	1.87e-04	45	144	4	CID000004463
Drug	foscarnet	COL2A1 ERVK-6 COL5A1 COL11A2 POLG PSME4 TRIM37	2.12e-04	190	144	7	CID000003414
Drug	Thioguanosine [85-31-4]; Up 200; 12.6uM; MCF7; HT_HG-U133A	COL5A1 TRIO SPTAN1 AIRE BLZF1 SNCA CAMSAP1	2.12e-04	190	144	7	2619_UP
Drug	2-propylpentanoic acid; Up 200; 1000uM; SKMEL5; HG-U133A	ARID4A XDH RAB11FIP1 ATP2C1 KCNH2 SLC17A7 N4BP1	2.26e-04	192	144	7	629_UP
Drug	Gramine [87-52-5]; Up 200; 23uM; MCF7; HT_HG-U133A	TFEB KLHL1 MAP1A MECOM FKBP8 SNCA RAB11FIP3	2.33e-04	193	144	7	4118_UP
Drug	Pramoxine hydrochloride [637-58-1]; Up 200; 12.2uM; PC3; HT_HG-U133A	COL2A1 AIRE MECOM NR6A1 NCOR2 AHNAK N4BP1	2.33e-04	193	144	7	3811_UP
Drug	Gallamine triethiodide [65-29-2]; Down 200; 4.4uM; MCF7; HT_HG-U133A	NES POLG IRGQ BLZF1 GPALPP1 N4BP1 ZMYM3	2.33e-04	193	144	7	6215_DN
Drug	methsuximide	CACNA1I TRIM37	2.36e-04	4	144	2	CID000006476
Drug	cinchonine	KCNH2 SLC47A1	2.36e-04	4	144	2	ctd:C010086
Drug	W-13, hydrochloride; Up 200; 10uM; MCF7; HG-U133A	COL5A1 NR6A1 FCHO1 TYK2 CACNA1I FKBP8 FYB1	2.41e-04	194	144	7	440_UP
Drug	Dirithromycin [62013-04-1]; Down 200; 4.8uM; HL60; HG-U133A	ANGEL1 IRGQ STAT1 PHKG2 TRIM28 N4BP1 FKBP8	2.41e-04	194	144	7	1712_DN
Drug	PHA-00745360 [351320-33-7]; Down 200; 10uM; PC3; HT_HG-U133A	TFEB RTEL1 CHD3 N4BP1 TSC22D4 PLK3 RAB11FIP3	2.41e-04	194	144	7	4559_DN
Drug	Omeprazole [73590-58-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A	RTEL1 PCDHGA10 KCNH2 SLC17A7 TSC22D4 CAMSAP1 FYB1	2.41e-04	194	144	7	4951_UP
Drug	Methyl benzethonium chloride [25155-18-4]; Down 200; 8.6uM; MCF7; HT_HG-U133A	TFEB NES RTEL1 APBA3 ITPKB SLC47A1 N4BP1	2.48e-04	195	144	7	3850_DN
Drug	Clorsulon [60200-06-8]; Down 200; 10.6uM; PC3; HT_HG-U133A	COL5A1 NIBAN1 IRGQ FCHO1 ITPKB PSME4 ZNF282	2.48e-04	195	144	7	7264_DN
Drug	Hemicholinium bromide [312-45-8]; Down 200; 7uM; PC3; HT_HG-U133A	TRIO SPTAN1 APBA3 CACNA1I FKBP8 TSC22D4 FYB1	2.48e-04	195	144	7	6739_DN
Drug	Ethamsylate [2624-44-4]; Up 200; 15.2uM; PC3; HT_HG-U133A	PCDHGA10 UBR4 KDM6B SLC17A7 CACNA1I ABCC2 CAMSAP1	2.48e-04	195	144	7	4576_UP
Drug	Sulfadiazine [68-35-9]; Down 200; 16uM; MCF7; HT_HG-U133A	CHD3 KCNH2 ATP2C2 FKBP8 PLXNA1 BRWD1 RAB11FIP3	2.48e-04	195	144	7	1688_DN
Drug	radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; PC3; HT_HG-U133A	KDM6B KCNH2 CACNA1I ABCC2 CAMSAP1 FYB1 PDZD2	2.56e-04	196	144	7	4443_UP
Drug	Deptropine citrate [2169-75-7]; Up 200; 7.6uM; HL60; HT_HG-U133A	SPTAN1 NR6A1 NCOR2 SLC17A7 CACNA1I SNCA PLXNA1	2.56e-04	196	144	7	3144_UP
Drug	Trimethoprim [738-70-5]; Down 200; 13.8uM; PC3; HT_HG-U133A	POLG APBA3 CHD3 KDM6B FKBP8 TSC22D4 RAB11FIP3	2.56e-04	196	144	7	7377_DN
Drug	Fluvoxamine maleate [61718-82-9]; Up 200; 9.2uM; MCF7; HT_HG-U133A	TFEB AIRE NR6A1 SLC17A7 FKBP8 TSC22D4 SNCA	2.56e-04	196	144	7	4114_UP
Drug	alpha-estradiol; Up 200; 0.01uM; HL60; HT_HG-U133A	MAP1A POLG UBR4 BLZF1 FCHO1 N4BP1 SNCA	2.56e-04	196	144	7	1151_UP
Drug	Digoxigenin [1672-46-4]; Down 200; 10.2uM; MCF7; HT_HG-U133A	ITPKB NYNRIN ABCC2 TSC22D4 SNCA CAMSAP1 PLK3	2.56e-04	196	144	7	3397_DN
Drug	Benfotiamine [22457-89-2]; Up 200; 8.6uM; MCF7; HT_HG-U133A	SETD1B TRIO NCOR2 KCNH2 CAMSAP1 ZNF282 PLK3	2.56e-04	196	144	7	3837_UP
Drug	Proadifen hydrochloride [62-68-0]; Up 200; 10.2uM; PC3; HT_HG-U133A	TFEB COL5A1 RRAGB BLZF1 TSC22D4 PLK3 BRWD1	2.56e-04	196	144	7	5807_UP
Drug	351A	COL2A1 COL5A1 COL11A2	2.61e-04	20	144	3	CID000122144
Drug	Sulpiride [15676-16-1]; Up 200; 11.8uM; PC3; HG-U133A	SETD1B ARID4A CHD3 KDM6B KDM4D ATP2C1 SLC17A7	2.64e-04	197	144	7	1887_UP
Drug	0317956-0000 [391210-11-0]; Down 200; 1uM; PC3; HT_HG-U133A	TOM1 APBB1 SLC4A3 PSME4 TSC22D4 PLK3 RAB11FIP3	2.64e-04	197	144	7	3777_DN
Drug	WY-14643; Up 200; 100uM; PC3; HG-U133A	NIBAN1 KLHL1 NR6A1 FCHO1 STAT1 CACNA1I PLXNA1	2.64e-04	197	144	7	464_UP
Drug	Glycopyrrolate [596-51-0]; Down 200; 10uM; PC3; HT_HG-U133A	RTEL1 KDM6B BAHD1 CEP68 KDM4D ATP2C1 RAB11FIP3	2.64e-04	197	144	7	7386_DN
Drug	Talampicillin hydrochloride [39878-70-1]; Up 200; 7.8uM; MCF7; HT_HG-U133A	PCDHGA10 TOM1 IRF6 KCNH2 ABCC2 SNCA FYB1	2.64e-04	197	144	7	7014_UP
Drug	Trichlorfon [52-68-6]; Up 200; 15.6uM; MCF7; HT_HG-U133A	SETD1B MAP1A XDH NR6A1 KLF2 CEP68 SLC47A1	2.64e-04	197	144	7	1675_UP
Drug	Griseofulvin [126-07-8]; Up 200; 11.2uM; PC3; HT_HG-U133A	COL2A1 COL5A1 PCDHGA10 NR6A1 SLC17A7 CACNA1I N4BP1	2.64e-04	197	144	7	3664_UP
Drug	Trolox [53188-07-1]; Up 200; 16uM; PC3; HT_HG-U133A	TRIO RRAGB ATP2C2 ZNF74 N4BP1 SNCA RAB11FIP3	2.64e-04	197	144	7	7304_UP
Drug	6-Furfurylaminopurine [525-79-1]; Down 200; 18.6uM; PC3; HT_HG-U133A	MAP1A RTEL1 APBA3 KLF2 PHKG2 FKBP8 RAB11FIP3	2.64e-04	197	144	7	4477_DN
Drug	Cinoxacin [28657-80-9]; Down 200; 15.2uM; MCF7; HT_HG-U133A	POLG MECOM IRGQ KDM6B ATP2C2 CCDC15 RAB11FIP3	2.64e-04	197	144	7	6257_DN
Drug	Todralazine hydrochloride [3778-76-5]; Down 200; 14.8uM; PC3; HT_HG-U133A	POLG TOM1 CHD3 KDM6B PSME4 FKBP8 TSC22D4	2.64e-04	197	144	7	1799_DN
Drug	Etilefrine hydrochloride [534-87-2]; Down 200; 18.4uM; MCF7; HT_HG-U133A	RTEL1 FCHO1 BAHD1 STAT1 ITPKB KCNH2 ZMYM3	2.64e-04	197	144	7	7350_DN
Drug	Sulfamethizole [144-82-1]; Down 200; 14.8uM; MCF7; HT_HG-U133A	COL5A1 XDH CHD3 CEP68 CACNA1I SNCA PLK3	2.64e-04	197	144	7	6099_DN
Drug	Benzonatate [104-31-4]; Down 200; 6.6uM; PC3; HT_HG-U133A	RTEL1 TOM1 CHD3 PSME4 FKBP8 TSC22D4 CAMSAP1	2.64e-04	197	144	7	1801_DN
Drug	Flunisolide [3385-03-3]; Down 200; 9.2uM; MCF7; HT_HG-U133A	TFEB TRIO SPTAN1 IRF6 KDM6B KLF2 FYB1	2.72e-04	198	144	7	6023_DN
Drug	Viomycin sulfate [37883-00-4]; Up 200; 5.2uM; PC3; HT_HG-U133A	RAB11FIP1 BLZF1 CEP68 KDM4D ATP2C1 PLK3 BRWD1	2.72e-04	198	144	7	7278_UP
Drug	Metformin hydrochloride [1115-70-4]; Down 200; 24.2uM; PC3; HT_HG-U133A	COL5A1 TOM1 APBB1 APBA3 PHKG2 FKBP8 TSC22D4	2.72e-04	198	144	7	1816_DN
Drug	Sisomicin sulfate [53179-09-2]; Up 200; 2.8uM; HL60; HT_HG-U133A	RTEL1 PCDHGA10 APBB1 SLC17A7 CACNA1I SNCA RAB11FIP3	2.72e-04	198	144	7	2493_UP
Drug	Zimelidine dihydrochloride monohydrate [61129-30-4]; Up 200; 9.8uM; PC3; HT_HG-U133A	TRIO AIRE XDH SLC17A7 ABCC2 SNCA FYB1	2.72e-04	198	144	7	4609_UP
Drug	Pizotifen malate [5189-11-7]; Up 200; 9.4uM; HL60; HT_HG-U133A	NES POLG AIRE BLZF1 NCOR2 SNCA FYB1	2.72e-04	198	144	7	3134_UP
Drug	0173570-0000 [211245-44-2]; Up 200; 1uM; PC3; HT_HG-U133A	POLG SPTAN1 NCOR2 NYNRIN ATP2C2 SNCA FYB1	2.72e-04	198	144	7	7391_UP
Drug	Sulfabenzamide [127-71-9]; Down 200; 14.4uM; MCF7; HT_HG-U133A	TRIO POLG SPTAN1 ITPKB SLC47A1 FKBP8 RAB11FIP3	2.72e-04	198	144	7	4979_DN
Drug	Naproxen [22204-53-1]; Down 200; 17.4uM; HL60; HT_HG-U133A	SPTAN1 BLZF1 FCHO1 STAT1 CEP68 UBR5 N4BP1	2.72e-04	198	144	7	1869_DN
Drug	15(S)-15-methyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A	RTEL1 SPTAN1 ANGEL1 SLC4A3 FCHO1 PHKG2 ZNF74	2.72e-04	198	144	7	7526_DN
Drug	Pyrithyldione [77-04-3]; Up 200; 24uM; MCF7; HT_HG-U133A	TRIO RTEL1 APBA3 SLC47A1 N4BP1 FKBP8 SNCA	2.72e-04	198	144	7	3482_UP
Drug	Cholecalciferol [67-97-0]; Up 200; 10.4uM; HL60; HT_HG-U133A	MAP1A AIRE NCOR2 SLC17A7 CACNA1I ABCC2 FYB1	2.72e-04	198	144	7	2436_UP
Drug	Amoxapine [14028-44-5]; Down 200; 12.8uM; HL60; HG-U133A	IRGQ CD320 TSSC4 KDM6B ATP2C1 N4BP1 ZNF282	2.72e-04	198	144	7	2013_DN
Drug	2-propylpentanoic acid; Up 200; 50uM; PC3; HT_HG-U133A	SPTAN1 STAT1 NCOR2 N4BP1 SNCA PLK3 PLXNA1	2.72e-04	198	144	7	1222_UP
Drug	Promazine hydrochloride [53-60-1]; Up 200; 12.4uM; HL60; HT_HG-U133A	NES MAP1A RTEL1 NR6A1 AHNAK SLC17A7 FKBP8	2.72e-04	198	144	7	2173_UP
Drug	Cephalothin sodium salt [58-71-9]; Down 200; 9.6uM; PC3; HT_HG-U133A	RTEL1 APBB1 BAHD1 STAT1 AHNAK N4BP1 SNCA	2.72e-04	198	144	7	4482_DN
Drug	Diflunisal [22494-42-4]; Down 200; 16uM; MCF7; HT_HG-U133A	COL5A1 MAP1A PCDHGA10 APBA3 BLZF1 CAMSAP1 ZNF282	2.72e-04	198	144	7	4794_DN
Drug	Pyrazinamide [ 98-96-4]; Down 200; 32.4uM; MCF7; HT_HG-U133A	ARID4A TOM1 IRF6 TSSC4 ITPKB CEP68 CAMSAP1	2.72e-04	198	144	7	4962_DN
Drug	Bisoprolol fumarate; Up 200; 9uM; PC3; HT_HG-U133A	TFEB PCDHGA10 BLZF1 CEP68 AHNAK ATP2C2 N4BP1	2.72e-04	198	144	7	6748_UP
Drug	PF-01378883-00 [351320-41-7]; Up 200; 10uM; PC3; HT_HG-U133A	CHD3 CEP68 ATP2C2 ZNF74 CACNA1I TSC22D4 PLK3	2.81e-04	199	144	7	6410_UP
Drug	Levocabastine hydrochloride [79547-78-7]; Down 200; 8.8uM; MCF7; HT_HG-U133A	NES TRIO BAHD1 STAT1 CEP68 ATP2C1 PTPRF	2.81e-04	199	144	7	7009_DN
Drug	Allantoin [97-59-6]; Up 200; 25.2uM; MCF7; HT_HG-U133A	PCDHGA10 FCHO1 KCNH2 FKBP8 CAMSAP1 FYB1 PDZD2	2.81e-04	199	144	7	5471_UP
Drug	Diperodon hydrochloride [537-12-2]; Down 200; 9.2uM; MCF7; HT_HG-U133A	TRIO RRAGB TSSC4 FCHO1 ITPKB KLF2 ATP2C2	2.81e-04	199	144	7	6836_DN
Drug	clozapine; Up 200; 10uM; PC3; HT_HG-U133A	TRIO RTEL1 POLG ANGEL1 SLC4A3 ZNF74 RAB11FIP3	2.81e-04	199	144	7	1229_UP
Drug	Delcorine; Down 200; 8.4uM; MCF7; HT_HG-U133A	TFEB TOM1 KCNH2 CACNA1I FYB1 ZNF282 PLXNA1	2.81e-04	199	144	7	6033_DN
Drug	Vigabatrin [60643-86-9]; Up 200; 31uM; MCF7; HT_HG-U133A	COL5A1 TRIO ITPKB SLC17A7 N4BP1 SNCA PLK3	2.81e-04	199	144	7	5415_UP
Drug	Caffeic acid [3331-39-5]; Up 200; 22.2uM; PC3; HT_HG-U133A	TFEB COL5A1 PCDHGA10 POLG SPTAN1 CEP68 ATP2C2	2.81e-04	199	144	7	6753_UP
Drug	Oxethazaine [126-27-2]; Down 200; 8.6uM; MCF7; HT_HG-U133A	TRIO KRI1 MECOM CHD3 ITPKB CEP68 N4BP1	2.81e-04	199	144	7	1484_DN
Disease	Intellectual Disability	TRIO TSEN54 CHD3 KDM6B TBC1D20 SCN1A SCN3A LAS1L GOT2 RAI1 PHACTR1	6.60e-06	447	134	11	C3714756
Disease	cleft palate (is_implicated_in)	COL2A1 COL11A2 IRF6	1.96e-05	12	134	3	DOID:674 (is_implicated_in)
Disease	Otospondylomegaepiphyseal dysplasia	COL2A1 COL11A2	2.05e-05	2	134	2	C4520892
Disease	Stickler syndrome, type 3	COL2A1 COL11A2	2.05e-05	2	134	2	C1861481
Disease	Megaepiphyseal dwarfism	COL2A1 COL11A2	2.05e-05	2	134	2	C1855310
Disease	short QT syndrome (implicated_via_orthology)	SLC4A3 KCNH2	6.12e-05	3	134	2	DOID:0050793 (implicated_via_orthology)
Disease	Craniofacial Abnormalities	COL2A1 COL11A2 IRF6 ALX4 TRIM37 RAI1	8.15e-05	156	134	6	C0376634
Disease	migraine disorder, diastolic blood pressure	ARID4A IRAG1 NCOR2	1.96e-04	25	134	3	EFO_0006336, MONDO_0005277
Disease	response to venlafaxine	POLG ANGEL1 LRRC74A	1.96e-04	25	134	3	EFO_0006328
Disease	Stickler syndrome	COL2A1 COL11A2	2.03e-04	5	134	2	cv:C0265253
Disease	Cardiac Arrest	SLC4A3 KCNH2	2.03e-04	5	134	2	C0018790
Disease	testosterone measurement	TFEB DDR1 MAP1A XDH MECOM KDM6B ZBTB7B TYK2 CEP68 NCOR2 PTPRF ANAPC1 NYNRIN PALM3 RAI1 BRWD1	2.26e-04	1275	134	16	EFO_0004908
Disease	Cartilage Diseases	COL2A1 COL11A2	3.03e-04	6	134	2	C0007302
Disease	Chondromalacia	COL2A1 COL11A2	3.03e-04	6	134	2	C0085700
Disease	Hailey-Hailey disease (implicated_via_orthology)	ATP2C1 ATP2C2	3.03e-04	6	134	2	DOID:0050429 (implicated_via_orthology)
Disease	Seizures	POLG TBC1D20 SLC17A7 ABCC2 GOT2 PHACTR1	4.97e-04	218	134	6	C0036572
Disease	Eczema	COL15A1 RTEL1 ZBTB7B CCDC88B ANAPC1 ARHGAP27 RAI1	5.56e-04	310	134	7	HP_0000964
Disease	chemotherapy-induced alopecia, methylcobalamin deficiency type cblE	TRIO TMEM132C	5.63e-04	8	134	2	EFO_0005400, MONDO_0009354
Disease	Ventricular Fibrillation	SLC4A3 KCNH2	5.63e-04	8	134	2	C0042510
Disease	Ehlers-Danlos syndrome (is_implicated_in)	COL5A1 TNXB	7.22e-04	9	134	2	DOID:13359 (is_implicated_in)
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN1A SCN3A	8.99e-04	10	134	2	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN1A SCN3A	8.99e-04	10	134	2	DOID:0080422 (implicated_via_orthology)
Disease	JT interval	SLC4A3 FMNL3 KCNH2 TSC22D4 RAI1 BRWD1	9.72e-04	248	134	6	EFO_0007885
Disease	gastric adenocarcinoma (is_implicated_in)	RTEL1 UBR5	1.10e-03	11	134	2	DOID:3717 (is_implicated_in)
Disease	Shortened QT interval	SLC4A3 KCNH2	1.10e-03	11	134	2	C0151879
Disease	Sensory hearing loss	COL2A1 COL11A2	1.10e-03	11	134	2	C1691779
Disease	Heart Diseases	XDH SLC4A3 ABCC2	1.21e-03	46	134	3	C0018799
Disease	Methionine sulfoxide measurement	TMEM132C SLC23A3	1.31e-03	12	134	2	EFO_0021650
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN1A SCN3A	1.31e-03	12	134	2	DOID:0060170 (implicated_via_orthology)
Disease	response to xenobiotic stimulus	KLHL1 UBR4 NKX2-6 SCN1A N4BP1	1.49e-03	182	134	5	GO_0009410
Disease	N-acetyl-isoputreanine measurement	KCNH2 SLC47A1	1.55e-03	13	134	2	EFO_0800107
Disease	multiple myeloma	TOM1 MECOM KLF2 ANKRD11	1.73e-03	112	134	4	EFO_0001378
Disease	platelet component distribution width	MECOM PWWP2A CEP68 NCOR2 NYNRIN TSC22D4 FYB1 TNXB BRWD1 RAB11FIP3	2.40e-03	755	134	10	EFO_0007984
Disease	Limb Deformities, Congenital	COL11A2 IRF6	2.66e-03	17	134	2	C0206762
Disease	cervical artery dissection	IRAG1 PHACTR1	2.66e-03	17	134	2	EFO_1000059
Disease	migraine disorder, systolic blood pressure	IRAG1 PHACTR1	2.99e-03	18	134	2	EFO_0006335, MONDO_0005277
Disease	Global developmental delay	CHD3 TBC1D20 GOT2 PHACTR1	3.22e-03	133	134	4	C0557874
Disease	osteochondrodysplasia (is_implicated_in)	COL2A1 COL11A2	3.33e-03	19	134	2	DOID:2256 (is_implicated_in)
Disease	Profound Mental Retardation	TSEN54 KDM6B SCN1A RAI1	3.77e-03	139	134	4	C0020796
Disease	Mental Retardation, Psychosocial	TSEN54 KDM6B SCN1A RAI1	3.77e-03	139	134	4	C0025363
Disease	Mental deficiency	TSEN54 KDM6B SCN1A RAI1	3.77e-03	139	134	4	C0917816
Disease	osteoarthritis, hip, osteoarthritis, knee, total joint arthroplasty	NCOR2 BRWD1	4.06e-03	21	134	2	EFO_0004616, EFO_0010726, EFO_1000786
Disease	ulcerative colitis	RTEL1 UBR4 TOM1 TYK2 TNRC18 TNXB	4.36e-03	335	134	6	EFO_0000729
Disease	renal system measurement, blood urea nitrogen measurement	UNCX MECOM	4.46e-03	22	134	2	EFO_0004741, EFO_0004742
Disease	anxiety disorder (implicated_via_orthology)	SCN1A SCN3A	4.46e-03	22	134	2	DOID:2030 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LGEPELPPDSDTVGM	ALX4	161	Q9H161
MVFAPGEKPGNEPEE	AKAIN1	1	P0CW23
PDGAVPTMADDLGEP	SLC4A3	461	P48751
PLKEDEDAMPLIGPE	ARID4A	941	P29374
VEESLAPPEEMPPGA	ANKRD11	2156	Q6UB99
GPDPGELAPAELEML	CCDC88B	191	A6NC98
PMSGEQPPRLEAEGG	CEP68	36	Q76N32
DPEGVVLKDLGPPMV	DDR1	146	Q08345
LEALDGPAMETLPEP	AJM1	56	C9J069
SGPPAMDLEGPRDIL	APBA3	11	O96018
EMREAEAAPGPPGAL	ACAP3	796	Q96P50
PKLDADMPEVAVEGP	AHNAK	2351	Q09666
AEEASQEPEMAPLGP	APBB1	96	O00213
PSDEAPMELGLKEPE	APBB1	321	O00213
MEAPPDGAADLVPLD	CAMSAP1	16	Q5T5Y3
MDGPPAQSLGVEPVD	ATP2C1	741	P98194
MDGPPAQSLGVEPVD	ATP2C2	771	O75185
EVRGPPGEPLAGMDT	AIRE	376	O43918
PIIDIAPMDIGGPEQ	COL2A1	1461	P02458
MEELGLASQPPEGRP	RAI1	1501	Q7Z5J4
EPPGGPCEAVLEMDA	NKX2-6	71	A6NCS4
ALEDPSPELMEGPEE	RAB11FIP3	446	O75154
MVGDLPDADIKPPEN	PPIL4	226	Q8WUA2
LMDGAAAVPEPSEDP	PALM3	51	A6NDB9
YPEIPLEEMPDADGV	MECOM	21	Q03112
EVLLAEIGRPPGPEM	ANAPC1	1271	Q9H1A4
GGDLMPAPADPTARE	FCHO1	541	O14526
EDGIEPVSPPEGMTE	NCOR2	2216	Q9Y618
LALAPAPSLPGDMGD	MAP1A	2316	P78559
MDGETAEEQGGPVPP	MAPKAPK3	1	Q16644
GEEAPQPMPSVPEDL	GOLGA8T	436	H3BQL2
PIRGAGDGMETEEPP	BLZF1	16	Q9H2G9
PEPADLGEEEPMLGL	GJC2	136	Q5T442
DMDADPGGPEFLKTP	FLYWCH1	411	Q4VC44
EILPEGDATTMGPPV	CD320	171	Q9NPF0
TPGAMEPAGEEERPP	KIAA2026	6	Q5HYC2
DDIEAMRAGVLPPPP	KCNH2	286	Q12809
EEAPGPPGVSRADML	KDM6B	1076	O15054
EAAMPHIPEDEEPPG	IRAG1	41	Q9Y6F6
PPELGERPDELGFVM	PLXNA1	1116	Q9UIW2
AAGMRFPLPEAIDPD	PCDHGA10	151	Q9Y5H3
EGMTPAGAVLPGDPL	PDZD2	1331	O15018
GFPAPPKQLDMGDEV	FYB1	636	O15117
GEEAPQPMPSVPEDL	GOLGA8Q	436	H3BV12
GEPAVLEPGMLVEGP	COL11A2	386	P13942
AIFSDEDPLLPPAMG	COG8	291	Q96MW5
PGDPMDQEDLGPCSE	POLG	521	P54098
PEAESGVDRGEPEPM	NCBP3	26	Q53F19
DKVPGPLEIPSGMED	NES	1511	P48681
PLEIPSGMEDAGPGA	NES	1516	P48681
PEPEPLPEDGALMDK	KDM4D	486	Q6B0I6
TAGSPGMPPDEIEIE	LRRC74A	21	Q0VAA2
LDEQGPPGAPRSEMD	LURAP1	156	Q96LR2
PLGRMPGQTEDPAEL	LAS1L	651	Q9Y4W2
GSLMGPESPPAQEEE	KRI1	621	Q8N9T8
PDLEMLPGGDLAEIG	ABCC2	741	Q92887
MELDLELPPGTGGSP	PABIR1	6	Q96E09
PFPIMGPEEEGDSAA	PHKG2	381	P15735
PLDQAGLMDPVDPED	PASD1	331	Q8IV76
VLQPSDIMDGPDPGA	PHACTR1	211	Q9C0D0
PSVVGAGEPMDLGEL	PRPF19	151	Q9UMS4
LEPMPPGEGAQEGEP	ERVK-10	286	P87889
LEPMPPGEGAQEGEP	ERVK-19	286	Q9YNA8
LEPMPPGEGAQEGEP	ERVK-21	286	P62683
LEPMPPGEGAQEGEP	ERVK-24	286	P63145
LEPMPPGEGAQEGEP	ERVK-6	286	Q7LDI9
LEPMPPGEGAQEGEP	ERVK-7	286	P63130
LEPMPPGEGAQEGEP	ERVK-8	286	P62685
LEPMPPGEGAQEGEP	ERVK-9	286	P63126
LELMPPGEGAQEGEP	HERVK_113	286	P62684
MRTEAEAAGPPLEPG	GUCD1	1	Q96NT3
ELPPLEDMGQPPAEE	FKBP8	51	Q14318
EDMGQPPAEEAEQPG	FKBP8	56	Q14318
MAEPGEGLPEEVLAL	FBXL8	1	Q96CD0
PLEDEVPGVPGEMEP	CHD3	1616	Q12873
PDPDVLEISMQTPGG	LINC02908	46	Q6ZV77
MGNLESAEGVPGEPP	FMNL3	1	Q8IVF7
PDGQEMGLPNPEEVK	GAGE10	91	A6NGK3
DSKGELDPPEPMRVG	CACNA1I	1886	Q9P0X4
SEDEDIIGPMPAKGP	GPALPP1	141	Q8IXQ4
GQPVDLSAMPPAPED	CC2D1B	326	Q5T0F9
PPIPGLESTMGVEED	CC2D1B	446	Q5T0F9
GDVPEPGAAREALMP	DNAAF8	501	Q8IYS4
EQGVEGVEPGMPESP	BAHD1	31	Q8TBE0
GEPAIIEPGMLIEGP	COL5A1	456	P20908
PGPQPTMEGDVLDTL	FAM98B	6	Q52LJ0
MEPIPDNVDPPEELG	BRWD1	1121	Q9NSI6
MDLDELSLFGPLPGP	CYTIP	216	O60759
SGDVAAPEPIMGEPG	C1orf127	401	Q8N9H9
APEPIMGEPGQASEE	C1orf127	406	Q8N9H9
PFEDMELSGEPVPEG	COL15A1	286	P39059
LIAPESAAPEEAMGP	NLRP6	151	P59044
GLVVDMLLGLDPGDP	IRGQ	236	Q8WZA9
EEEQLPPGFPSIDMG	PTPRF	126	P10586
FMVPDDPLGRDGPTL	NYNRIN	926	Q9P2P1
EEMEPEGQPSPDGCL	ARHGAP30	896	Q7Z6I6
LGPMPDQEELFGPVS	IRF6	256	O14896
LPGGLPSPEDAMVTE	TESMIN	6	Q9Y4I5
EDLEPLGTPMLIEDG	NR6A1	261	Q15406
PGMEPPGPQEERLAV	RTEL1	1141	Q9NZ71
VMELPEQDGGRALPP	RTL1	981	A6NKG5
MAAPGDPQDELLPLA	RTN1	1	Q16799
GAPQEGILEDMPVDP	SNCA	106	P37840
NGEEAPGPDPSLDRM	SYTL1	221	Q8IYJ3
DAAEEVAPPLPMGAS	RAB11FIP1	766	Q6WKZ4
AMGAAPLGEPAKEDP	SOHLH1	271	Q5JUK2
PLGEPAKEDPMLAQE	SOHLH1	276	Q5JUK2
GEAEPEMEPIPGSEA	PWWP2A	21	Q96N64
EMEPIPGSEAGTDPL	PWWP2A	26	Q96N64
PVLPEGASAAPEEGM	TRIM37	886	O94972
PGEALMLGAEVPDPE	TFEB	356	P19484
EAPEPMELDGPKGTG	STAT1	686	P42224
MEPEPEPAAVEVPAG	TSEN54	1	Q7Z6J9
NEAELLESMGDAPPP	TMEM132C	976	Q8N3T6
LGAPEEMGQVPPLDS	TSC22D4	246	Q9Y3Q8
MPGSGEPEVGKRPEE	ITPKB	381	P27987
DELPAPGSPEMERAG	PIK3R6	351	Q5UE93
PEEELEMQPGLSPGS	ARHGAP27	336	Q6ZUM4
PAEDVPLLLMNPEAG	POLR3A	231	O14802
DPGLMPLPDTATGLD	SIPA1L2	1561	Q9P2F8
REPPEEPGLSQEGAM	SETD1B	1266	Q9UPS6
DSEMEDEAEPPGAPP	SLC17A7	521	Q9P2U7
GDIPPEMVSEPLEDL	SCN3A	66	Q9NY46
EMADLLPGSGEPCPE	SLC23A3	586	Q6PIS1
MEAPEEPAPVRGGPE	SLC47A1	1	Q96FL8
LEPMPPGEGAQEGEP	ERVK-9	286	P63128
GDIPPEMVSEPLEDL	SCN1A	66	P35498
VEMGPPDPILGVTEA	GOT2	36	P00505
LPPSLMPGDGIEDEE	CCDC15	146	Q0P6D6
PFPEMLGEEPLLEVE	ANGEL1	126	Q9UNK9
EVEDMDEGPTELPPL	TNRC18	1161	O15417
PELEMLAGLPTSDPG	PLK3	36	Q9H4B4
GEPGDVQEMPAPESP	RNF149	321	Q8NC42
MGSPEDDLIGIPFPD	ZBTB7B	1	O15156
EPAPGSEPMAVPDLD	VSIG1	331	Q86XK7
PDGIPLLDPIDDMGI	MTREX	771	P42285
EPLGPMEGELPGEAC	NIBAN1	806	Q9BZQ8
LPFGELDLDSMAPPA	TMEM52	131	Q8NDY8
AEPAADLIDMGPDPA	TOM1	316	O60784
GYDLPMVEEGEPDPE	SPTAN1	2356	Q13813
GDEPPILPDMGNRVT	TMED3	121	Q9Y3Q3
SMEAPEPAEEPLLGE	TNXB	2086	P22105
PGGAEVEALSPMGLP	TSSC4	41	Q9Y5U2
AEELHLPPDAPGGMV	XDH	491	P47989
EKENLGPRMDPPLGE	RRAGB	11	Q5VZM2
MEPAERAGVGEPPEP	PSME4	1	Q14997
LEEPPMAGPAAEAER	PRR33	146	A8MZF0
EEPAQEPIMERPLGG	ZNF74	131	Q16587
PPGMPEEQREGLQEE	TBC1D20	111	Q96BZ9
LPQGPAQLSPGEMEE	ZBTB32	321	Q9Y2Y4
ELIGPMLEPGDEEPQ	XAGE3	21	Q8WTP9
GAEGFPPMLDIPPDA	UBR4	2796	Q5T4S7
PEKPLAGDLPVDMEF	ZMYM3	16	Q14202
IPMDPEAGAEPLVPA	ZNF282	271	Q9UDV7
EEGADAVPLPPPMAI	TRIO	1861	O75962
PVLMALAEGPGAEGP	TRIM28	576	Q13263
PAMDPDGDIDFILAP	UBR5	1031	O95071
EAPMREAEAGPPQVG	nan	11	Q6ZQT7
PEEGKMDDEDPLVPG	TYK2	616	P29597
AAAGPSPPEGEELDM	UNCX	516	A6NJT0
GEEAPQPMPSVPEDL	GOLGA8IP	436	A6NC78
GEEAPQPMPSVPEDL	GOLGA8N	436	F8WBI6
MGLDGLGAEAAPEPP	KLF2	51	Q9Y5W3
EEEVVPGMDFPGPHE	KLHL1	126	Q9NR64
DIFMVPDDPLGRSGP	N4BP1	751	O75113