Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	Ank_2	ASPG NFKB2 ESPNL TNKS ANKRD52 NOTCH1	9.33e-05	215	64	6	PF12796
Domain	-	ASPG NFKB2 ESPNL TNKS ANKRD52 NOTCH1	2.03e-04	248	64	6	1.25.40.20
Domain	ANK	ASPG NFKB2 ESPNL TNKS ANKRD52 NOTCH1	2.17e-04	251	64	6	SM00248
Domain	ANK_REPEAT	ASPG NFKB2 ESPNL TNKS ANKRD52 NOTCH1	2.26e-04	253	64	6	PS50088
Domain	Ankyrin_rpt-contain_dom	ASPG NFKB2 ESPNL TNKS ANKRD52 NOTCH1	2.31e-04	254	64	6	IPR020683
Domain	ANK_REP_REGION	ASPG NFKB2 ESPNL TNKS ANKRD52 NOTCH1	2.31e-04	254	64	6	PS50297
Domain	Ankyrin_rpt	ASPG NFKB2 ESPNL TNKS ANKRD52 NOTCH1	2.73e-04	262	64	6	IPR002110
Domain	Ank	NFKB2 ESPNL TNKS ANKRD52 NOTCH1	1.10e-03	228	64	5	PF00023
Domain	GRAM	TBC1D8 NSMAF	1.34e-03	16	64	2	SM00568
Domain	GRAM	TBC1D8 NSMAF	2.55e-03	22	64	2	PF02893
Domain	GRAM	TBC1D8 NSMAF	2.55e-03	22	64	2	IPR004182
Domain	WGR_domain	TNKS ART5	3.04e-03	24	64	2	IPR008893
Domain	Ribosomal_S5_D2-typ_fold	GALK1 EXOSC4	6.04e-03	34	64	2	IPR020568
Pubmed	The LIM homeodomain factor Lhx2 is required for hypothalamic tanycyte specification and differentiation.	TH NKX2-1 ESR1 NOTCH1	9.58e-08	23	65	4	25505333
Pubmed	Interaction between estrogen receptor-α and PNPLA3 p.I148M variant drives fatty liver disease susceptibility in women.	ESR1 PNPLA3	3.44e-06	2	65	2	37749332
Pubmed	Sexual cues influence cocaine-induced locomotion, anxiety and the immunoreactivity of oestrogen receptor alpha and tyrosine hydroxylase in both sexes.	TH ESR1	3.44e-06	2	65	2	31009113
Pubmed	Notch/Rbpjκ signaling regulates progenitor maintenance and differentiation of hypothalamic arcuate neurons.	TH NKX2-1 NOTCH1	4.98e-06	18	65	3	23884446
Pubmed	Cellular fate decisions in the developing female anteroventral periventricular nucleus are regulated by canonical Notch signaling.	TH ESR1 NOTCH1	5.91e-06	19	65	3	29885287
Pubmed	Tissue-selective expression of a conditionally-active ROCK2-estrogen receptor fusion protein.	ROCK2 ESR1	1.03e-05	3	65	2	27775859
Pubmed	Molecular dependence of estrogen receptor-negative breast cancer on a notch-survivin signaling axis.	ESR1 NOTCH1	1.03e-05	3	65	2	18593928
Pubmed	Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches.	ESR1 NOTCH1	1.03e-05	3	65	2	18593923
Pubmed	Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinases.	ROCK2 NOTCH1	2.06e-05	4	65	2	17344417
Pubmed	Genomic structure and chromosomal localization of the mouse LIM/homeobox gene Lhx3.	SPTAN1 NOTCH1	2.06e-05	4	65	2	7665181
Pubmed	Cloning, analysis, and chromosomal localization of Notch-1, a mouse homolog of Drosophila Notch.	SPTAN1 NOTCH1	2.06e-05	4	65	2	8449489
Pubmed	Endocytosis and intracellular processing of BODIPY-sphingomyelin by murine CATH.a neurons.	SMPD2 NSMAF	2.06e-05	4	65	2	23973266
Pubmed	Estrogen receptors in granulosa cells govern meiotic resumption of pre-ovulatory oocytes in mammals.	NPR2 ESR1	2.06e-05	4	65	2	28277543
Pubmed	Forebrain Ptf1a Is Required for Sexual Differentiation of the Brain.	TH NKX2-1 ESR1	2.44e-05	30	65	3	29972793
Pubmed	An atlas of genetic influences on human blood metabolites.	ADHFE1 ASPG PYROXD2 SLC7A6 PRODH	2.92e-05	190	65	5	24816252
Pubmed	Distinct adapter proteins mediate acid versus neutral sphingomyelinase activation through the p55 receptor for tumor necrosis factor.	SMPD2 NSMAF	3.43e-05	5	65	2	9620659
Pubmed	Multigene family for sarcomeric myosin heavy chain in mouse and human DNA: localization on a single chromosome.	MYH2 GALK1	3.43e-05	5	65	2	6879174
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	PLEKHH1 PRR12 KIF26A KCNH3	4.27e-05	103	65	4	10574462
Pubmed	Spatiotemporal patterns of sortilin and SorCS2 localization during organ development.	TH NKX2-1	5.13e-05	6	65	2	26964886
Pubmed	Detection and Quantification of Multiple RNA Sequences Using Emerging Ultrasensitive Fluorescent In Situ Hybridization Techniques.	TH NKX2-1	5.13e-05	6	65	2	30791216
Pubmed	Notch-1 activates estrogen receptor-alpha-dependent transcription via IKKalpha in breast cancer cells.	ESR1 NOTCH1	5.13e-05	6	65	2	19838210
Pubmed	MYPT1, the targeting subunit of smooth-muscle myosin phosphatase, is a substrate for the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH).	TNKS NOTCH1	7.18e-05	7	65	2	19245366
Pubmed	Aberrant trajectory of ascending dopaminergic pathway in mice lacking Nkx2.1.	TH NKX2-1	7.18e-05	7	65	2	12821380
Pubmed	The Bmp8 gene is expressed in developing skeletal tissue and maps near the Achondroplasia locus on mouse chromosome 4.	NPR2 CSF3R	7.18e-05	7	65	2	9070944
Pubmed	Null mutation of Dlx-2 results in abnormal morphogenesis of proximal first and second branchial arch derivatives and abnormal differentiation in the forebrain.	TH NKX2-1	7.18e-05	7	65	2	7590232
Pubmed	Direct Parabrachial-Cortical Connectivity.	TH ESR1	9.56e-05	8	65	2	32383444
Pubmed	Sonic hedgehog is a chemoattractant for midbrain dopaminergic axons.	TH NKX2-1	9.56e-05	8	65	2	19774071
Pubmed	MEK-SHP2 inhibition prevents tibial pseudarthrosis caused by NF1 loss in Schwann cells and skeletal stem/progenitor cells.	TH PRSS56	9.56e-05	8	65	2	38924432
Pubmed	Isolation and characterization of the human and mouse homologues (SUPT4H and Supt4h) of the yeast SPT4 gene.	SPTAN1 NOTCH1	9.56e-05	8	65	2	8786137
Pubmed	Regional and cell-type-specific afferent and efferent projections of the mouse claustrum.	TH NKX2-1 ESR1	1.15e-04	50	65	3	36774552
Pubmed	Telomere shortening in neural stem cells disrupts neuronal differentiation and neuritogenesis.	ROCK2 TH	1.23e-04	9	65	2	19923274
Pubmed	Conditional deletion of neurogenin-3 using Nkx2.1iCre results in a mouse model for the central control of feeding, activity and obesity.	TH ESR1	1.23e-04	9	65	2	23649822
Pubmed	Anatomical characterization of Cre driver mice for neural circuit mapping and manipulation.	TH NKX2-1 ESR1	1.29e-04	52	65	3	25071457
Pubmed	Radial and tangential migration of telencephalic somatostatin neurons originated from the mouse diagonal area.	TH NKX2-1	1.53e-04	10	65	2	26189100
Pubmed	Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.	NPR2 GALK1 CSF3R BCKDK PRODH	1.70e-04	276	65	5	28319085
Pubmed	Early construction of the thalamocortical axon pathway requires c-Jun N-terminal kinase signaling within the ventral forebrain.	TH NKX2-1	1.87e-04	11	65	2	34494344
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PRR12 FNTB KIF26A PCNX4 NFKB2 TBC1D25 ATP2A3 NOTCH1 KCNH3	2.07e-04	1105	65	9	35748872
Pubmed	Mouse GLI3 regulates Fgf8 expression and apoptosis in the developing neural tube, face, and limb bud.	TH NKX2-1	2.24e-04	12	65	2	12435361
Pubmed	Notch signaling promotes airway mucous metaplasia and inhibits alveolar development.	NKX2-1 NOTCH1	2.24e-04	12	65	2	19369400
Pubmed	YAP regulates the expression of Hoxa1 and Hoxc13 in mouse and human oral and skin epithelial tissues.	FGF3 NOTCH1	2.24e-04	12	65	2	25691658
Pubmed	Identification of midbrain floor plate radial glia-like cells as dopaminergic progenitors.	TH NOTCH1	2.24e-04	12	65	2	18351630
Pubmed	Patterning of the basal telencephalon and hypothalamus is essential for guidance of cortical projections.	TH NKX2-1	2.24e-04	12	65	2	11830575
Pubmed	Notch signaling coordinates the patterning of striatal compartments.	TH NOTCH1	2.65e-04	13	65	2	16120638
Pubmed	Eya1 is required for the morphogenesis of mammalian thymus, parathyroid and thyroid.	NKX2-1 FGF3	2.65e-04	13	65	2	12070080
Pubmed	Mash1 regulates neurogenesis in the ventral telencephalon.	TH NKX2-1	2.65e-04	13	65	2	9876181
Pubmed	SOX2 hypomorphism disrupts development of the prechordal floor and optic cup.	NKX2-1 NOTCH1	2.65e-04	13	65	2	22522080
Pubmed	Human tyrosinase gene, mapped to chromosome 11 (q14----q21), defines second region of homology with mouse chromosome 7.	TH FGF3	3.08e-04	14	65	2	3146546
Pubmed	Genetic linkage analysis of the Ak1, Col5a1, Epb7.2, Fpgs, Grp78, Pbx3, and Notch1 genes in the region of mouse chromosome 2 homologous to human chromosome 9q.	SPTAN1 NOTCH1	3.08e-04	14	65	2	8088777
Pubmed	Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways.	NKX2-1 NOTCH1	3.08e-04	14	65	2	22797898
Pubmed	The transcription factors Grainyhead-like 2 and NK2-homeobox 1 form a regulatory loop that coordinates lung epithelial cell morphogenesis and differentiation.	NKX2-1 NOTCH1	3.08e-04	14	65	2	22955271
Pubmed	Genetic interactions between Pax9 and Msx1 regulate lip development and several stages of tooth morphogenesis.	FGF3 NOTCH1	3.08e-04	14	65	2	20123092
Pubmed	Maps from two interspecific backcross DNA panels available as a community genetic mapping resource.	GALK1 SPTAN1 NOTCH1	3.39e-04	72	65	3	8075499
Pubmed	Ripply3, a Tbx1 repressor, is required for development of the pharyngeal apparatus and its derivatives in mice.	NKX2-1 FGF3	3.56e-04	15	65	2	21177346
Pubmed	NOTCH1 is required for regeneration of Clara cells during repair of airway injury.	NKX2-1 NOTCH1	3.56e-04	15	65	2	22331706
Pubmed	BMP receptor 1A regulates development of hypothalamic circuits critical for feeding behavior.	TH NKX2-1	3.56e-04	15	65	2	23197713
Pubmed	Distinct temporal requirements for Sonic hedgehog signaling in development of the tuberal hypothalamus.	TH NKX2-1	3.56e-04	15	65	2	30291164
Pubmed	Decoding neuronal composition and ontogeny of individual hypothalamic nuclei.	TH NKX2-1	3.56e-04	15	65	2	33600763
Pubmed	A role for Gsh1 in the developing striatum and olfactory bulb of Gsh2 mutant mice.	TH NKX2-1	3.56e-04	15	65	2	11731457
Pubmed	Financial and psychological risk attitudes associated with two single nucleotide polymorphisms in the nicotine receptor (CHRNA4) gene.	TH ESR1	4.06e-04	16	65	2	19693267
Pubmed	Fbxw7α- and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma.	NFKB2 NOTCH1	4.06e-04	16	65	2	22388891
Pubmed	Aurora B opposes PP1 function in mitosis by phosphorylating the conserved PP1-binding RVxF motif in PP1 regulatory proteins.	CDCA2 MPHOSPH10	4.06e-04	16	65	2	29764992
Pubmed	Genetic ablation of the Rho GTPase Rnd3 triggers developmental defects in internal capsule and the globus pallidus formation.	TH NKX2-1	4.06e-04	16	65	2	33576044
Pubmed	Alk5-mediated transforming growth factor β signaling acts upstream of fibroblast growth factor 10 to regulate the proliferation and maintenance of dental epithelial stem cells.	FGF3 NOTCH1	4.06e-04	16	65	2	21402782
Pubmed	Notch Dosage: Jagged1 Haploinsufficiency Is Associated With Reduced Neuronal Division and Disruption of Periglomerular Interneurons in Mice.	TH NOTCH1	4.06e-04	16	65	2	32161758
Pubmed	Olig2 defines a subset of neural stem cells that produce specific olfactory bulb interneuron subtypes in the subventricular zone of adult mice.	TH NKX2-1	4.59e-04	17	65	2	35132995
Pubmed	Slit2 activity in the migration of guidepost neurons shapes thalamic projections during development and evolution.	TH NKX2-1	4.59e-04	17	65	2	21435555
Pubmed	Involvement of TRAF4 in oxidative activation of c-Jun N-terminal kinase.	TBC1D8 BCKDK	4.59e-04	17	65	2	12023963
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	SPTAN1 BCKDK TNKS CLASRP	5.16e-04	197	65	4	20811636
Pubmed	OL-Protocadherin is essential for growth of striatal axons and thalamocortical projections.	TH NKX2-1	5.16e-04	18	65	2	17721516
Pubmed	CAMSAP3 is required for mTORC1-dependent ependymal cell growth and lateral ventricle shaping in mouse brains.	TH CAMSAP3	5.16e-04	18	65	2	33462112
Pubmed	Molecular and behavioral profiling of Dbx1-derived neurons in the arcuate, lateral and ventromedial hypothalamic nuclei.	TH ESR1	5.16e-04	18	65	2	27209204
Pubmed	Chromosomal mapping of Adam9, Adam15 and Adam21.	FNTB TNKS	5.16e-04	18	65	2	10842103
Pubmed	Epithelial Notch signaling regulates lung alveolar morphogenesis and airway epithelial integrity.	NKX2-1 NOTCH1	5.16e-04	18	65	2	27364009
Pubmed	BCL11B regulates epithelial proliferation and asymmetric development of the mouse mandibular incisor.	FGF3 NOTCH1	5.76e-04	19	65	2	22629441
Pubmed	Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum.	TH NKX2-1	5.76e-04	19	65	2	10393115
Pubmed	Vascular abnormalities in mice lacking the endothelial gap junction proteins connexin37 and connexin40.	TH NKX2-1	5.76e-04	19	65	2	12435353
Pubmed	Mind bomb-1 is essential for intraembryonic hematopoiesis in the aortic endothelium and the subaortic patches.	TH NOTCH1	5.76e-04	19	65	2	18505817
Pubmed	Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk.	NPR2 ESR1	5.76e-04	19	65	2	25342443
Pubmed	Frizzled3 Controls Axonal Polarity and Intermediate Target Entry during Striatal Pathway Development.	TH NKX2-1	5.76e-04	19	65	2	26490861
Pubmed	Single cell transcriptome analysis of developing arcuate nucleus neurons uncovers their key developmental regulators.	TH ESR1	5.76e-04	19	65	2	31420539
Pubmed	Patterning of ventral telencephalon requires positive function of Gli transcription factors.	TH NKX2-1	6.39e-04	20	65	2	19632216
Pubmed	Mash1 is required for generic and subtype differentiation of hypothalamic neuroendocrine cells.	TH NKX2-1	6.39e-04	20	65	2	16469766
Pubmed	The histone H3-lysine 4-methyltransferase Mll4 regulates the development of growth hormone-releasing hormone-producing neurons in the mouse hypothalamus.	TH NKX2-1	6.39e-04	20	65	2	33431871
Pubmed	Notch signaling augments the canonical Wnt pathway to specify the size of the otic placode.	FGF3 NOTCH1	6.39e-04	20	65	2	18495817
Pubmed	Inactivation of Arx, the murine ortholog of the X-linked lissencephaly with ambiguous genitalia gene, leads to severe disorganization of the ventral telencephalon with impaired neuronal migration and differentiation.	TH NKX2-1	6.39e-04	20	65	2	17460091
Pubmed	A Highly Conserved Shh Enhancer Coordinates Hypothalamic and Craniofacial Development.	TH NKX2-1	7.06e-04	21	65	2	33869166
Pubmed	An estrogen-responsive module in the ventromedial hypothalamus selectively drives sex-specific activity in females.	NKX2-1 ESR1	7.06e-04	21	65	2	25543145
Pubmed	Regulation of the protocadherin Celsr3 gene and its role in globus pallidus development and connectivity.	TH NKX2-1	7.06e-04	21	65	2	25113559
Pubmed	Proteomic analysis of a detergent-resistant membrane skeleton from neutrophil plasma membranes.	MYH2 SPTAN1	7.06e-04	21	65	2	12202484
Pubmed	Prss56, a novel marker of adult neurogenesis in the mouse brain.	TH PRSS56	7.06e-04	21	65	2	26701169
Pubmed	Diabetogenic response to streptozotocin varies among obese yellow and among lean agouti (BALB/c x VY)F1 hybrid mice.	TH PRSS56	7.06e-04	21	65	2	2137249
Pubmed	Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease.	ROCK2 ESR1 NFKB2	7.40e-04	94	65	3	20346360
Pubmed	An Eya1-Notch axis specifies bipotential epibranchial differentiation in mammalian craniofacial morphogenesis.	FGF3 NOTCH1	7.76e-04	22	65	2	29140246
Pubmed	Genome-wide association study identifies five new breast cancer susceptibility loci.	ESR1 FGF3	7.76e-04	22	65	2	20453838
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	TBC1D8 CRIM1 PYROXD2 SPG11 KIF5C SLC7A6 ATP2A3 NOTCH1	7.91e-04	1061	65	8	33845483
Pubmed	Notch signaling controls the balance of ciliated and secretory cell fates in developing airways.	NKX2-1 NOTCH1	8.48e-04	23	65	2	19502490
Pubmed	Loss of function of the maternal membrane oestrogen receptor ERα alters expansion of trophoblast cells and impacts mouse fertility.	ESR1 NOTCH1	8.48e-04	23	65	2	36239412
Pubmed	Chromosomal localization of the proteasome Z subunit gene reveals an ancient chromosomal duplication involving the major histocompatibility complex.	SPTAN1 NOTCH1	8.48e-04	23	65	2	8799160
Pubmed	Notch signalling regulates epibranchial placode patterning and segregation.	FGF3 NOTCH1	8.48e-04	23	65	2	31988190
Pubmed	Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons.	TH ESR1	8.48e-04	23	65	2	29795232
GeneFamily	Ankyrin repeat domain containing	ASPG NFKB2 ESPNL TNKS ANKRD52 NOTCH1	1.42e-05	242	40	6	403
GeneFamily	WD repeat domain containing\|GRAM domain containing\|BEACH domain containing	TBC1D8 NSMAF	3.67e-04	13	40	2	1146
Coexpression	LIM_MAMMARY_STEM_CELL_DN	TBC1D8 HDHD3 ZDHHC24 CMC1 FNTB ESR1 PYROXD2 CAMSAP3	8.77e-06	417	65	8	M2574
Coexpression	LIM_MAMMARY_STEM_CELL_DN	TBC1D8 HDHD3 ZDHHC24 CMC1 FNTB ESR1 PYROXD2 CAMSAP3	1.21e-05	436	65	8	MM1326
Disease	histidine measurement, amino acid measurement	ASPG PRODH	1.26e-05	3	61	2	EFO_0005134, EFO_0009769
Disease	alanine measurement, amino acid measurement	ASPG PRODH	1.26e-05	3	61	2	EFO_0005134, EFO_0009765
Disease	asparagine measurement, amino acid measurement	KIF26A ASPG	2.52e-05	4	61	2	EFO_0005134, EFO_0009766
Disease	tyrosine measurement, amino acid measurement	ASPG PRODH	2.52e-05	4	61	2	EFO_0005058, EFO_0005134
Disease	phenylalanine measurement, amino acid measurement	ASPG PRODH	4.19e-05	5	61	2	EFO_0005001, EFO_0005134
Disease	proline measurement, amino acid measurement	ASPG PRODH	4.19e-05	5	61	2	EFO_0005134, EFO_0009773
Disease	fructose-1,6-bisphosphatase 1 measurement	PCNX4 PNPLA3	6.27e-05	6	61	2	EFO_0801606
Disease	Neoplasm of uncertain or unknown behavior of breast	ESR1 FGF3 NOTCH1	8.47e-05	41	61	3	C0496956
Disease	Breast adenocarcinoma	ESR1 FGF3 NOTCH1	8.47e-05	41	61	3	C0858252
Disease	amino acid measurement, threonine measurement	ASPG PRODH	8.77e-05	7	61	2	EFO_0005134, EFO_0009775
Disease	Malignant neoplasm of breast	ADHFE1 MAN2C1 ESR1 SPTAN1 FGF3 ATP2A3 NOTCH1 PRODH CLASRP	3.43e-04	1074	61	9	C0006142
Disease	caudal middle frontal gyrus volume measurement	PCNX4 NSMAF	6.30e-04	18	61	2	EFO_0010290
Disease	metabolite measurement	ADHFE1 ASPG PYROXD2 PNPLA3 SLC7A6 PRODH	1.04e-03	560	61	6	EFO_0004725
Disease	Cerebral Astrocytoma	ESR1 NOTCH1	1.22e-03	25	61	2	C0750935
Disease	Intracranial Astrocytoma	ESR1 NOTCH1	1.22e-03	25	61	2	C0750936
Disease	Pilocytic Astrocytoma	ESR1 NOTCH1	1.22e-03	25	61	2	C0334583
Disease	Astrocytoma	ESR1 NOTCH1	1.22e-03	25	61	2	C0004114
Disease	Juvenile Pilocytic Astrocytoma	ESR1 NOTCH1	1.22e-03	25	61	2	C0280783
Disease	Diffuse Astrocytoma	ESR1 NOTCH1	1.22e-03	25	61	2	C0280785
Disease	Grade I Astrocytoma	ESR1 NOTCH1	1.22e-03	25	61	2	C1704230
Disease	Subependymal Giant Cell Astrocytoma	ESR1 NOTCH1	1.22e-03	25	61	2	C0205768
Disease	Mixed oligoastrocytoma	ESR1 NOTCH1	1.22e-03	25	61	2	C0547065
Disease	Childhood Cerebral Astrocytoma	ESR1 NOTCH1	1.22e-03	25	61	2	C0338070
Disease	Gemistocytic astrocytoma	ESR1 NOTCH1	1.32e-03	26	61	2	C0334581
Disease	Protoplasmic astrocytoma	ESR1 NOTCH1	1.32e-03	26	61	2	C0334580
Disease	Fibrillary Astrocytoma	ESR1 NOTCH1	1.32e-03	26	61	2	C0334582
Disease	Anaplastic astrocytoma	ESR1 NOTCH1	1.43e-03	27	61	2	C0334579
Disease	Parkinsonism (implicated_via_orthology)	ESR1 NFKB2	1.65e-03	29	61	2	DOID:0080855 (implicated_via_orthology)
Disease	age at first birth measurement	ESR1 TNKS KCNH3	1.99e-03	120	61	3	EFO_0009101
Disease	neutrophil count	TBC1D8 CSF3R FNTB UHMK1 PNPLA3 RNF183 CPNE4 PRODH ARHGAP19	2.04e-03	1382	61	9	EFO_0004833

Protein segments in the cluster

Peptide	Gene	Start	Entry
NLMPLLEGRASHSDH	ARSH	406	Q5FYA8
MALDPADQHLRHVEK	CMC1	1	Q7Z7K0
HAPEIARMALALLDA	NPR2	926	P20594
ARRGIHDMFPLHLAV	ANKRD52	366	Q8NB46
RMLATHHLALHEDKP	BCKDK	201	O14874
DLRHQPILMGAHLAV	CAMSAP3	126	Q9P1Y5
MEAAHLLPAADVLRH	ATP2A3	1	Q93084
LSAPEREHLASMIHL	NKX2-1	186	P43699
ALRLAHMEPVVAAHV	HDHD3	176	Q9BSH5
LPDELRADIAMHLHK	KCNH3	561	Q9ULD8
MVRNVDDLDFHLPSH	KLHL30	1	Q0D2K2
AMHSALDPVLDAHLN	PAN2	16	Q504Q3
IALLEMDARLHEDHL	EXOSC4	196	Q9NPD3
ADVHLRALDGMSALH	ESPNL	196	Q6ZVH7
LPRDIAQERMHHDIV	NOTCH1	2096	P46531
PDHHVAVDMLALANA	LINS1	326	Q8NG48
AAILRTLPMFHDEEH	ASPG	36	Q86U10
SLFLPRVLDHRDHEM	FGF3	176	P11487
DLAHRFVVNMPALEH	PCNX4	226	Q63HM2
LEMLDAHRLHAPTSR	ESR1	541	P03372
HHEVDHFLREMPALI	OR2W3	171	Q7Z3T1
TPGAMEHELVLHQLR	MYH2	686	Q9UKX2
EHAPHLLRDARMLFG	PNPLA3	31	Q9NST1
LEASAAPHAMRHIQE	GALK1	356	P51570
LEETLHFDHAVRMAP	MPHOSPH10	401	O00566
TREAMHLLQAPASHE	KIF26A	136	Q9ULI4
DHEALMATLFVRHSP	SMPD2	271	O60906
ADTREAIVHASHLPM	CPNE4	451	Q96A23
SENDIVHLPRDMGHL	CRIM1	906	Q9NZV1
ALTRLHAMARDPHSL	CSF3R	431	Q99062
FHRDVHMLLVDLELL	MAN2C1	181	Q9NTJ4
KDLLRHDPDLHMHQG	CDCA2	636	Q69YH5
LHRALHAQGDPALSM	FNTB	311	P49356
MPGTKRHHFDLLAEL	NSMAF	746	Q92636
LSDIHHRMPAILDGE	HMCES	206	Q96FZ2
VPSEHLAMNFHEVLA	PRSS56	496	P0CW18
PDDLEARSHMHLASA	ADHFE1	301	Q8IWW8
TDTAMLALLRLEPHH	RNF183	76	Q96D59
DLASPILAVMDHEGH	TBC1D25	336	Q3MII6
MGIIPRIAHDIFDHI	KIF5C	106	O60282
EHDHVLPLQELAMRG	LRRC28	266	Q86X40
ALRRMEELGLHPADH	PRODH	506	O43272
LHEATMPVLLDHLRE	FAM13C	506	Q8NE31
MPLQLEAHLRSHGLE	PRR12	846	Q9ULL5
MIDRFDVRAHLDHIP	CLASRP	76	Q8N2M8
EASMEDLHPEIHALL	SPG11	1921	Q96JI7
PARAELINIHHLMVE	VPS52	701	Q8N1B4
RMGVPFLLHEDHLDV	UNC80	471	Q8N2C7
MPHLSADIESAHIER	SYNGAP1	1161	Q96PV0
MHRLALAIDPLLDAA	PYROXD2	166	Q8N2H3
HKRLEAELAAHEPAI	SPTAN1	1806	Q13813
HLPELAEHMNDLSAL	TBC1D8	646	O95759
PLHVAAERAHNDVME	TNKS	561	O95271
ALDAIHSMGLIHRDV	ROCK2	201	O75116
EALRELFQHVHDMPE	ARHGAP19	371	Q14CB8
RHGAPAEQLRHLADM	PLEKHH1	1181	Q9ULM0
LSALLRAHTPLHMAA	ZDHHC24	161	Q6UX98
LHHPMAVDLGELDSL	ZNF697	166	Q5TEC3
HLPDLLSMIHIERFT	SLC7A6	351	Q92536
MRIPHSHAFIDLTED	ITFG1	201	Q8TB96
HLRDLIKSMLHDDPS	UHMK1	276	Q8TAS1
LAHLGRHMEALEIAA	ZHX1-C8orf76	71	Q96EF9
HELLGHVPMLADRTF	TH	361	P07101
APLLKEEMAHHALLR	ART5	51	Q96L15
ADPALLDRHGDSAMH	NFKB2	551	Q00653