Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	IQSEC_PH	IQSEC2 IQSEC1	1.39e-04	3	128	2	IPR033742
Domain	IQ_SEC7_PH	IQSEC2 IQSEC1	1.39e-04	3	128	2	PF16453
Domain	RUN	RUSC1 RUSC2 SGSM2	2.38e-04	18	128	3	SM00593
Domain	DNA_pol_B	POLD1 POLE	2.77e-04	4	128	2	PF00136
Domain	DNA-dir_DNA_pol_B	POLD1 POLE	2.77e-04	4	128	2	IPR006172
Domain	DNA-dir_DNA_pol_B_exonuc	POLD1 POLE	2.77e-04	4	128	2	IPR006133
Domain	DNA-dir_DNA_pol_B_multi_dom	POLD1 POLE	2.77e-04	4	128	2	IPR006134
Domain	DNA_pol_B_exo1	POLD1 POLE	2.77e-04	4	128	2	PF03104
Domain	POLBc	POLD1 POLE	2.77e-04	4	128	2	SM00486
Domain	RUN	RUSC1 RUSC2 SGSM2	2.81e-04	19	128	3	PS50826
Domain	RUN	RUSC1 RUSC2 SGSM2	2.81e-04	19	128	3	PF02759
Domain	Run_dom	RUSC1 RUSC2 SGSM2	2.81e-04	19	128	3	IPR004012
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	KIF13B UAP1 CARMIL2 KIF26B TBC1D5 IQSEC2 USP43 STK32C TRIP11 DENND1A CDC14A CARD8 LUZP1 MPRIP RUSC2 USP31 ABLIM1 VPS13D RESF1 CLMN KIAA1217 IQSEC1 NAV1 COBL MAP3K21	1.97e-15	861	131	25	36931259
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TNIK KIF13B CACNA1E CENPF TBC1D5 IQSEC2 SPATA20 TRIP11 TENM2 AKAP12 LUZP1 MPRIP NCOR1 ABLIM1 ZC2HC1A NETO1 KIAA1217 IQSEC1 NAV1 WDFY3 CABIN1 AGAP2	1.28e-11	963	131	22	28671696
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	CENPF VPS4B ATG2B DVL3 RUSC1 BIRC6 LUZP1 PRDM2 NCOR1 RESF1 GTF3C1 ZBTB10 NAV1 KIAA1958 CHD6	6.60e-11	418	131	15	34709266
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PRKD2 NDST1 SZT2 POLE SPATA20 SMG5 STK32C BIRC6 DENND1A MPRIP PIKFYVE SCAF1 NCOR1 MTMR14 SGSM2 NAV1 CENPV COBL WDFY3 CABIN1 SOWAHB WDR24	1.76e-10	1105	131	22	35748872
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	PRKD2 NDST1 DCHS2 PDE9A IQSEC2 PEG3 DVL3 SMG5 UBASH3A TRIP11 MPRIP THAP4 ABLIM1 FBN1 SBNO1 NETO1 SGSM2 DAAM2 CHD6 WDFY3 CABIN1 AGAP1 AGAP2	5.10e-10	1285	131	23	35914814
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	CAAP1 GCFC2 DAB2 TATDN2 MORC2 GPRIN1 PRDM2 SCAF1 NCOR1 MSH6 ABLIM1 BRD8 GTF3C1 MDC1 IQSEC1 KIAA1958	3.99e-08	774	131	16	15302935
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TNIK PEG3 TENM2 RUSC2 USP31 ABLIM1 ACOT11 SGSM2 NAV1 COBL DAAM2 CHD6	5.09e-08	407	131	12	12693553
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	TNIK GPRIN1 TRIP11 AKAP12 MPRIP USP31 ABLIM1 TFB1M KIAA1217 WDR20 COBL AGAP1	7.35e-08	421	131	12	36976175
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	TNIK PRKD2 POLD1 TBC1D5 IQSEC2 DVL3 DAB2 DENND1A RUSC2 ABLIM1 ZC2HC1A MTMR14 STRADA KIAA1217 WDR20 IQSEC1 LSM11 AGAP1	7.58e-08	1038	131	18	26673895
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	KIF13B FLG PDE9A POLD1 IQSEC2 ATG2B DVL3 TRIP11 DENND1A AKAP12 LUZP1 MPRIP USP21 ABLIM1 SBNO1 WDR20 NAV1 MAP3K21 AGAP1 WDR24	1.21e-07	1321	131	20	27173435
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	TNIK CACNA1E PCLO IQSEC2 GPRIN1 LUZP1 ABLIM1 IQSEC1 AGAP1 AGAP2	1.23e-07	281	131	10	28706196
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	TBC1D5 DAB2 RUSC1 DENND1A PIKFYVE MTMR14 WDR20 COBL WDFY3 MAP3K21	1.41e-07	285	131	10	34369648
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	CACNA1E PCLO GPRIN1 LUZP1 MPRIP ABLIM1 CLMN IQSEC1 AGAP2	2.52e-07	231	131	9	16452087
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PDE9A TSHZ2 TBC1D5 WNT4 STK32C DENND1A MAP3K12 THAP4 ABLIM1 GTF3C1 NETO1 CLMN SGSM2 KIAA1217 NAV1 COBL RASEF CHD6 OLFM2 AGAP1	7.99e-07	1489	131	20	28611215
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	CENPF KIF26B PCLO IQSEC2 MUC19 GPRIN1 BIRC6 PRDM2 SCAF1 MSH6 LOXHD1 GTF3C1 CHD6 CFAP44	8.00e-07	736	131	14	29676528
Pubmed	Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry.	PCLO UBASH3A LUZP1 DAAM2 AGAP2	2.10e-06	55	131	5	18570454
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	DCHS2 CENPF POLD1 MORC2 GPRIN1 SNX14 VPS13D LOXHD1 GTF3C1 SEPTIN1 COBL	3.09e-06	497	131	11	36774506
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	BORCS6 TMEM201 TBC1D5 ATG2B GPRIN1 TRIP11 AKAP12 PIKFYVE SNX14 VPS13D WDR24	3.53e-06	504	131	11	34432599
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	MUC19 NCOR1 FBN1 RESF1 NETO1 MDC1	7.54e-06	123	131	6	26912792
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	ATG2B GPRIN1 LUZP1 MPRIP NCOR1 MSH6 ABLIM1 BRD8 GTF3C1 CEBPZ MDC1	7.91e-06	549	131	11	38280479
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	MACC1 ABCF3 DVL3 USP43 GPRIN1 TRIP11 LUZP1 MPRIP ABLIM1 CLMN KIAA1217	1.03e-05	565	131	11	25468996
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	CAAP1 MACC1 POLD1 MORC2 DENND1A LUZP1 MPRIP SCAF1 MSH6 ABLIM1 BRD8 TFB1M CEBPZ MDC1 WDR20 LSM11 CHD6 AGAP1	1.36e-05	1497	131	18	31527615
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	TNIK KIF26B DAB2 GPRIN1 AKAP12 WDR20 DAAM2 DCUN1D3 AGAP1	1.39e-05	377	131	9	38117590
Pubmed	Race, Prevalence of POLE and POLD1 Alterations, and Survival Among Patients With Endometrial Cancer.	POLD1 POLE	1.41e-05	2	131	2	38231514
Pubmed	Combined mismatch repair and POLE/POLD1 defects explain unresolved suspected Lynch syndrome cancers.	POLD1 POLE	1.41e-05	2	131	2	26648449
Pubmed	AGAP1, an endosome-associated, phosphoinositide-dependent ADP-ribosylation factor GTPase-activating protein that affects actin cytoskeleton.	AGAP1 AGAP2	1.41e-05	2	131	2	12388557
Pubmed	Polymerase proofreading-associated polyposis: a new, dominantly inherited syndrome of hereditary colorectal cancer predisposition.	POLD1 POLE	1.41e-05	2	131	2	24509466
Pubmed	Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas.	POLD1 POLE	1.41e-05	2	131	2	23263490
Pubmed	Increased somatic mutation burdens in normal human cells due to defective DNA polymerases.	POLD1 POLE	1.41e-05	2	131	2	34594041
Pubmed	Short CCG repeat in huntingtin gene is an obstacle for replicative DNA polymerases, potentially hampering progression of replication fork.	POLD1 POLE	1.41e-05	2	131	2	26271349
Pubmed	Long patch base excision repair with purified human proteins. DNA ligase I as patch size mediator for DNA polymerases delta and epsilon.	POLD1 POLE	1.41e-05	2	131	2	10559260
Pubmed	ALFY-Controlled DVL3 Autophagy Regulates Wnt Signaling, Determining Human Brain Size.	DVL3 WDFY3	1.41e-05	2	131	2	27008544
Pubmed	Role of POLE and POLD1 in familial cancer.	POLD1 POLE	1.41e-05	2	131	2	32792570
Pubmed	POLE and POLD1 germline exonuclease domain pathogenic variants, a rare event in colorectal cancer from the Middle East.	POLD1 POLE	1.41e-05	2	131	2	32567205
Pubmed	POLE/POLD1 mutation and tumor immunotherapy.	POLD1 POLE	1.41e-05	2	131	2	35780178
Pubmed	Daam2 is required for dorsal patterning via modulation of canonical Wnt signaling in the developing spinal cord.	DVL3 DAAM2	1.41e-05	2	131	2	22227309
Pubmed	DNA polymerase ε and δ exonuclease domain mutations in endometrial cancer.	POLD1 POLE	1.41e-05	2	131	2	23528559
Pubmed	Human mismatch repair system balances mutation rates between strands by removing more mismatches from the lagging strand.	POLD1 POLE	1.41e-05	2	131	2	28512192
Pubmed	New insights into POLE and POLD1 germline mutations in familial colorectal cancer and polyposis.	POLD1 POLE	1.41e-05	2	131	2	24501277
Pubmed	Functional landscapes of POLE and POLD1 mutations in checkpoint blockade-dependent antitumor immunity.	POLD1 POLE	1.41e-05	2	131	2	35817971
Pubmed	The Arf GAPs AGAP1 and AGAP2 distinguish between the adaptor protein complexes AP-1 and AP-3.	AGAP1 AGAP2	1.41e-05	2	131	2	16079295
Pubmed	Germline and somatic polymerase ε and δ mutations define a new class of hypermutated colorectal and endometrial cancers.	POLD1 POLE	1.41e-05	2	131	2	23447401
Pubmed	Tumor-Infiltrating Lymphocytes, Tumor Mutational Burden, and Genetic Alterations in Microsatellite Unstable, Microsatellite Stable, or Mutant POLE/POLD1 Colon Cancer.	POLD1 POLE	1.41e-05	2	131	2	34250404
Pubmed	Rare germline variants in POLE and POLD1 encoding the catalytic subunits of DNA polymerases ε and δ in glioma families.	POLD1 POLE	1.41e-05	2	131	2	37990341
Pubmed	DNA polymerase ε and δ variants drive mutagenesis in polypurine tracts in human tumors.	POLD1 POLE	1.41e-05	2	131	2	38219146
Pubmed	Comprehensive analysis of POLE and POLD1 Gene Variations identifies cancer patients potentially benefit from immunotherapy in Chinese population.	POLD1 POLE	1.41e-05	2	131	2	31673068
Pubmed	Germline variants in POLE are associated with early onset mismatch repair deficient colorectal cancer.	POLD1 POLE	1.41e-05	2	131	2	25370038
Pubmed	POLE/POLD1 mutation in non-exonuclease domain matters for predicting efficacy of immune-checkpoint-inhibitor therapy.	POLD1 POLE	1.41e-05	2	131	2	34586735
Pubmed	Mutation spectrum of POLE and POLD1 mutations in South East Asian women presenting with grade 3 endometrioid endometrial carcinomas.	POLD1 POLE	1.41e-05	2	131	2	26748215
Pubmed	POLE and POLD1 mutations in 529 kindred with familial colorectal cancer and/or polyposis: review of reported cases and recommendations for genetic testing and surveillance.	POLD1 POLE	1.41e-05	2	131	2	26133394
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	TNIK KIF26B ATG2B DAB2 LUZP1 VPS13D COBL	1.52e-05	209	131	7	36779422
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	TNIK KIF13B PRKD2 CENPF POLD1 POLE MORC2 BIRC6 TRIP10 MSH6 GTF3C1 CEBPZ	1.53e-05	704	131	12	29955894
Pubmed	Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca2+/CaM) and CaM Kinase II (CaMKII) Binding Partner.	PCLO MPRIP ABLIM1 ZC2HC1A ACOT11 IQSEC1 AGAP2	3.05e-05	233	131	7	29518331
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	CACNA1E AKAP12 PIKFYVE SCAF1 NCOR1 RESF1 IQSEC1	3.05e-05	233	131	7	37704626
Pubmed	MORC2B is essential for meiotic progression and fertility.	MORC1 MORC2 SYCP2	4.09e-05	18	131	3	29329290
Pubmed	Effect of exogenous MSH6 and POLD1 expression on the mutation rate of the HPRT locus in a human colon cancer cell line with mutator phenotype, DLD-1.	POLD1 MSH6	4.21e-05	3	131	2	14767555
Pubmed	A CRISPR knockout screen identifies SETDB1-target retroelement silencing factors in embryonic stem cells.	MORC2 RESF1	4.21e-05	3	131	2	29728365
Pubmed	Distinctive activities of DNA polymerases during human DNA replication.	POLD1 POLE	4.21e-05	3	131	2	16762037
Pubmed	Segregation of replicative DNA polymerases during S phase: DNA polymerase ε, but not DNA polymerases α/δ, are associated with lamins throughout S phase in human cells.	POLD1 POLE	4.21e-05	3	131	2	22887995
Pubmed	Frameshift mutational target gene analysis identifies similarities and differences in constitutional mismatch repair-deficiency and Lynch syndrome.	POLD1 POLE	4.21e-05	3	131	2	28218421
Pubmed	Kif26b controls endothelial cell polarity through the Dishevelled/Daam1-dependent planar cell polarity-signaling pathway.	KIF26B DVL3	4.21e-05	3	131	2	26792835
Pubmed	The function of DNA polymerases in DNA repair synthesis of ultraviolet-irradiated human fibroblasts.	POLD1 POLE	4.21e-05	3	131	2	1730053
Pubmed	AP-4 vesicles contribute to spatial control of autophagy via RUSC-dependent peripheral delivery of ATG9A.	RUSC1 RUSC2	4.21e-05	3	131	2	30262884
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	TNIK IQSEC2 MPRIP ABLIM1 NETO1 IQSEC1 AGAP2	4.89e-05	251	131	7	27507650
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	TMEM201 ABCF3 POLD1 POLE BIRC6 LUZP1 MPRIP MSH6 ZC2HC1A GTF3C1 TFB1M CEBPZ MDC1 IQSEC1 ZBTB10 WDFY3	5.20e-05	1353	131	16	29467282
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	CACNA1E AMFR PCLO GPRIN1 RUSC2 ABLIM1 IQSEC1 AGAP2	5.40e-05	347	131	8	17114649
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	TNIK KIF13B CARMIL2 TBC1D5 USP43 WDR20 NAV1 COBL DCUN1D3 AGAP1	6.24e-05	569	131	10	30639242
Pubmed	SIVA1 directs the E3 ubiquitin ligase RAD18 for PCNA monoubiquitination.	POLD1 POLE MSH6	6.61e-05	21	131	3	24958773
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	KIF13B TRIP11 LUZP1 MPRIP PIKFYVE NCOR1 RESF1 KIAA1217 NAV1 CFAP44	8.19e-05	588	131	10	38580884
Pubmed	Subunit-selective N-Methyl-d-aspartate (NMDA) Receptor Signaling through Brefeldin A-resistant Arf Guanine Nucleotide Exchange Factors BRAG1 and BRAG2 during Synapse Maturation.	IQSEC2 IQSEC1	8.41e-05	4	131	2	26884337
Pubmed	DNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice.	POLD1 POLE	8.41e-05	4	131	2	19805137
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	PRKD2 CAAP1 POLD1 CRACR2B LUZP1 SCAF1 MSH6 BRD8 RESF1 WDR20 IQSEC1 ZBTB10 FOXL2NB WDFY3	8.49e-05	1116	131	14	31753913
Pubmed	Atmin mediates kidney morphogenesis by modulating Wnt signaling.	DVL3 WNT4 DAAM2	9.98e-05	24	131	3	24852369
Pubmed	Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.	IQSEC2 TENM2 EVI5 NETO1 IQSEC1 LSM11	1.06e-04	197	131	6	36604605
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	MORC2 PRDM2 MSH6 GTF3C1 SBNO1 MDC1 ZBTB10 CENPV CHD6 CABIN1	1.08e-04	608	131	10	36089195
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	TNIK GCFC2 VPS4B BIRC6 PIKFYVE ABLIM1 CEBPZ CLMN MDC1 NAV1 CHD6	1.09e-04	733	131	11	34672954
Pubmed	Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction.	PCLO KIAA1217 IQSEC1 CENPV AGAP2	1.43e-04	131	131	5	28634551
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	SZT2 MORC2 LUZP1 PRDM2 MPRIP COBL	1.43e-04	208	131	6	33230847
Pubmed	The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.	TNIK PCLO LUZP1 PIKFYVE ABLIM1 AGAP1	1.84e-04	218	131	6	33378226
Pubmed	AMPA receptor signaling through BRAG2 and Arf6 critical for long-term synaptic depression.	IQSEC2 IQSEC1	2.09e-04	6	131	2	20547133
Pubmed	Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.	MUC19 MUC16	2.09e-04	6	131	2	19110483
Pubmed	KR-POK interacts with p53 and represses its ability to activate transcription of p21WAF1/CDKN1A.	LCMT2 NCOR1	2.09e-04	6	131	2	22253232
Pubmed	MORC2 regulates DNA damage response through a PARP1-dependent pathway.	MORC1 MORC2	2.09e-04	6	131	2	31616951
Pubmed	A proteomics approach to identify proliferating cell nuclear antigen (PCNA)-binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein.	POLD1 POLE MSH6	2.17e-04	31	131	3	12171929
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	TNIK SMG5 BIRC6 ABLIM1 CHD6 WDFY3	2.19e-04	225	131	6	12168954
Pubmed	Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.	MAGEL2 TENM2 BRD8 TACR3 OLFM2	2.60e-04	149	131	5	25231870
Pubmed	The transcription factor Otx2 regulates choroid plexus development and function.	WNT4 FGF12 NEUROG2	2.62e-04	33	131	3	23364326
Pubmed	SYCP2 and SYCP3 are required for cohesin core integrity at diplotene but not for centromere cohesion at the first meiotic division.	SYCP2 STAG3	2.92e-04	7	131	2	15870106
Pubmed	Mapping specific protein-protein interactions within the core component of the breast cell DNA synthesome.	POLD1 POLE	2.92e-04	7	131	2	9563011
Pubmed	Characterization of WDR20: A new regulator of the ERAD machinery.	AMFR WDR20	2.92e-04	7	131	2	29655804
Pubmed	Glutamylation of an HIV-1 protein inhibits the immune response by hijacking STING.	AMFR TTLL6	2.92e-04	7	131	2	37099423
Pubmed	Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes.	MORC2 TRIP11 MSH6 MDC1	3.07e-04	85	131	4	16051665
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	TMEM201 TBC1D5 ATG2B DVL3 DAB2 TRIP11 AKAP12 LUZP1 VPS13D	3.15e-04	568	131	9	37774976
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	PRKD2 TMEM201 KIF27 CENPF POLD1 POLE PCLO PRDM2 SCAF1 MSH6 GTF3C1 SBNO1 CEBPZ MDC1 CENPV	3.18e-04	1425	131	15	30948266
Pubmed	Human transcription factor protein interaction networks.	FLG SMG5 MORC2 PRDM2 MPRIP NCOR1 BRD8 FBN1 RESF1 GTF3C1 MDC1 WDR20 ZBTB10 CHD6 CABIN1	3.28e-04	1429	131	15	35140242
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PCLO MPRIP NCOR1 WDFY3	3.36e-04	87	131	4	12465718
Pubmed	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	PRKD2 UBASH3A COBL	3.69e-04	37	131	3	19430480
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	SRSF4 TRIP10 LUZP1 MPRIP NCOR1 GTF3C1 CEBPZ MDC1 ZBTB10 CENPV COBL	3.76e-04	847	131	11	35850772
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	SRSF4 POLD1 PCLO SMG5 TENM2 GTF3C1 NAV1 LSM11	3.80e-04	462	131	8	31138677
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	TNIK PCLO IQSEC2 ATG2B DVL3 GPRIN1 BIRC6 TENM2 ABLIM1 KIAA1217 IQSEC1 NAV1 AGAP2	3.82e-04	1139	131	13	36417873
Interaction	YWHAH interactions	KIF13B PRKD2 UAP1 CARMIL2 KIF26B TBC1D5 IQSEC2 USP43 TRIP11 DENND1A CDC14A LUZP1 MPRIP USP21 RUSC2 USP31 ABLIM1 VPS13D RESF1 TFB1M CLMN KIAA1217 WDR20 NAV1 COBL MAP3K21 AGAP1	1.92e-09	1102	131	27	int:YWHAH
Interaction	SFN interactions	TNIK KIF13B UAP1 SRSF4 KIF26B POLD1 TBC1D5 TRIP11 DENND1A CARD8 LUZP1 MPRIP RUSC2 USP31 ABLIM1 CLMN NAV1 COBL MAP3K21	1.14e-07	692	131	19	int:SFN
Interaction	YWHAB interactions	KIF13B UAP1 CARMIL2 KIF26B POLD1 TBC1D5 IQSEC2 USP43 TRIP11 DENND1A CDC14A LUZP1 MPRIP RUSC2 USP31 ABLIM1 VPS13D WDR20 NAV1 MAP3K21 AGAP1 AGAP2	6.06e-07	1014	131	22	int:YWHAB
Interaction	YWHAQ interactions	KIF13B PRKD2 UAP1 CARMIL2 KIF26B TBC1D5 IQSEC2 USP43 TRIP11 DENND1A MAP3K12 CDC14A LUZP1 MPRIP RUSC2 USP31 ABLIM1 VPS13D WDR20 NAV1 MAP3K21 CABIN1 AGAP1	8.17e-07	1118	131	23	int:YWHAQ
Interaction	YWHAG interactions	KIF13B UAP1 CARMIL2 KIF26B TBC1D5 IQSEC2 USP43 TRIP11 DENND1A CDC14A LUZP1 MPRIP USP21 RUSC2 USP31 ABLIM1 VPS13D CLMN WDR20 IQSEC1 NAV1 COBL MAP3K21 AGAP1	1.50e-06	1248	131	24	int:YWHAG
Interaction	DCLK1 interactions	TNIK KIF13B DENND1A USP21 NAV1 MAP3K21 AGAP1 AGAP2	1.80e-06	127	131	8	int:DCLK1
Interaction	CDC25B interactions	KIF13B DENND1A CDC14A USP21 MSH6 NAV1 MAP3K21 AGAP1	2.70e-06	134	131	8	int:CDC25B
Interaction	NUP43 interactions	SZT2 POLD1 MUC19 MORC2 PRDM2 SCAF1 NCOR1 BRD8 FBN1 RESF1 NETO1 CEBPZ MDC1 ZBTB10 CHD6 FAM199X	3.07e-06	625	131	16	int:NUP43
Interaction	YWHAZ interactions	KIF13B PRKD2 UAP1 CARMIL2 KIF26B TBC1D5 IQSEC2 USP43 DENND1A CDC14A LUZP1 MPRIP USP21 RUSC2 USP31 NCOR1 ABLIM1 VPS13D MDC1 WDR20 NAV1 WDFY3 MAP3K21 AGAP1	3.92e-06	1319	131	24	int:YWHAZ
Interaction	YWHAE interactions	KIF13B MACC1 UAP1 CARMIL2 SRSF4 KIF26B TBC1D5 IQSEC2 USP43 TRIP11 DENND1A CDC14A LUZP1 MPRIP USP21 RUSC2 USP31 ABLIM1 WDR20 NAV1 FGF12 MAP3K21 AGAP1	5.80e-06	1256	131	23	int:YWHAE
Interaction	TOP3B interactions	PRKD2 NDST1 SZT2 CENPF POLE SPATA20 SMG5 STK32C BIRC6 DENND1A CDC14A MPRIP PIKFYVE SCAF1 NCOR1 MTMR14 SGSM2 MDC1 NAV1 CENPV COBL WDFY3 CABIN1 SOWAHB WDR24	7.81e-06	1470	131	25	int:TOP3B
Interaction	RTKN interactions	KIF13B DENND1A USP21 ACOT11 NAV1 MAP3K21 AGAP1	1.02e-05	115	131	7	int:RTKN
Interaction	AGAP1 interactions	KIF13B PRKD2 DENND1A USP21 NAV1 MAP3K21 AGAP1	1.14e-05	117	131	7	int:AGAP1
Interaction	PLEKHA7 interactions	KIF13B DENND1A CDC14A USP21 MAP3K21 SOWAHB AGAP1	1.28e-05	119	131	7	int:PLEKHA7
Interaction	NADK interactions	KIF13B DENND1A USP21 NAV1 MAP3K21 AGAP1	1.36e-05	80	131	6	int:NADK
Interaction	SIPA1L1 interactions	TNIK KIF13B POLD1 DENND1A USP21 NAV1 MAP3K21 AGAP1	1.84e-05	174	131	8	int:SIPA1L1
Interaction	SRSF12 interactions	KIF13B SRSF4 DENND1A USP21 NAV1 MAP3K21 AGAP1	2.27e-05	130	131	7	int:SRSF12
Interaction	ANKRD34A interactions	KIF13B DENND1A USP21 MAP3K21 AGAP1	2.40e-05	53	131	5	int:ANKRD34A
Interaction	CBY1 interactions	KIF13B DENND1A USP21 ABLIM1 NAV1 OLFM2 MAP3K21 AGAP1	2.55e-05	182	131	8	int:CBY1
Interaction	ATG9A interactions	AMFR TBC1D5 DAB2 RUSC1 DENND1A RUSC2 PIKFYVE MTMR14 WDR20 COBL WDFY3 MAP3K21	3.43e-05	445	131	12	int:ATG9A
Interaction	KDM1A interactions	TNIK CENPF VPS4B ATG2B DVL3 RUSC1 BIRC6 LUZP1 PRDM2 NCOR1 MSH6 RESF1 GTF3C1 KIAA1217 ZBTB10 NAV1 KIAA1958 CHD6	3.85e-05	941	131	18	int:KDM1A
Interaction	TESK2 interactions	KIF13B DENND1A USP21 NAV1 MAP3K21 AGAP1	4.10e-05	97	131	6	int:TESK2
Interaction	TBC1D25 interactions	KIF13B RUSC1 DENND1A USP21 AGAP1	4.41e-05	60	131	5	int:TBC1D25
Interaction	DENND1A interactions	KIF13B DENND1A USP21 NAV1 MAP3K21 AGAP1	5.14e-05	101	131	6	int:DENND1A
Interaction	CACNA1E interactions	TNIK CACNA1E AGAP2	5.66e-05	12	131	3	int:CACNA1E
Interaction	AGAP2 interactions	TNIK CACNA1E PCLO IQSEC2 LUZP1 MPRIP IQSEC1 AGAP2	7.03e-05	210	131	8	int:AGAP2
Interaction	FAM110B interactions	KIF13B DENND1A USP21 MAP3K21 AGAP1	7.52e-05	67	131	5	int:FAM110B
Interaction	FAM53C interactions	KIF13B DENND1A USP21 MAP3K21 AGAP1	8.07e-05	68	131	5	int:FAM53C
Interaction	SYDE1 interactions	KIF13B DENND1A USP21 NAV1 MAP3K21 AGAP1	8.29e-05	110	131	6	int:SYDE1
Interaction	LIMA1 interactions	KIF13B DAB2 DENND1A LUZP1 MPRIP USP21 ABLIM1 NAV1 COBL MAP3K21 AGAP1	1.15e-04	429	131	11	int:LIMA1
Interaction	PPM1H interactions	KIF13B DENND1A USP21 NAV1 MAP3K21 AGAP1	1.53e-04	123	131	6	int:PPM1H
Interaction	GIGYF1 interactions	KIF13B TSHZ2 DENND1A USP21 NAV1 MAP3K21 AGAP1	1.60e-04	177	131	7	int:GIGYF1
Interaction	LRFN1 interactions	KIF13B DENND1A USP21 NAV1 MAP3K21 AGAP1	1.60e-04	124	131	6	int:LRFN1
Interaction	NF1 interactions	KIF13B BIRC6 DENND1A USP21 NAV1 MAP3K21 AGAP1 AGAP2	1.67e-04	238	131	8	int:NF1
Interaction	DLGAP1 interactions	TNIK IQSEC2 MPRIP ABLIM1 KIAA1217 IQSEC1 AGAP2	1.78e-04	180	131	7	int:DLGAP1
Interaction	IQSEC2 interactions	TNIK IQSEC2 IQSEC1 AGAP2	1.89e-04	44	131	4	int:IQSEC2
Interaction	SH3PXD2A interactions	KIF13B DENND1A USP21 NAV1 MAP3K21 AGAP1	1.91e-04	128	131	6	int:SH3PXD2A
Interaction	MAST3 interactions	KIF13B DENND1A USP21 NAV1 MAP3K21 AGAP1	1.99e-04	129	131	6	int:MAST3
Interaction	FBXO22 interactions	DCHS2 CENPF POLD1 MORC2 GPRIN1 NCOR1 SNX14 VPS13D LOXHD1 GTF3C1 SEPTIN1 COBL	2.13e-04	540	131	12	int:FBXO22
Interaction	KSR1 interactions	KIF13B DENND1A USP21 NAV1 MAP3K21 AGAP1	2.25e-04	132	131	6	int:KSR1
Interaction	RNF123 interactions	CENPF KIF26B PCLO IQSEC2 MUC19 GPRIN1 BIRC6 LCMT2 PRDM2 SCAF1 MSH6 LOXHD1 GTF3C1 CHD6 CFAP44	3.04e-04	824	131	15	int:RNF123
Interaction	DENND4C interactions	KIF13B DENND1A USP21 NAV1 MAP3K21 AGAP1	3.10e-04	140	131	6	int:DENND4C
Interaction	HDAC7 interactions	KIF13B PRKD2 DENND1A AKAP12 NCOR1 ACOT11	3.22e-04	141	131	6	int:HDAC7
Interaction	KIF13B interactions	KIF13B DENND1A USP21 NAV1 MAP3K21 AGAP1	3.34e-04	142	131	6	int:KIF13B
Interaction	HDAC4 interactions	KIF13B PRKD2 CACNA1E SPATA20 SMG5 MORC2 DENND1A USP21 NCOR1 CLMN NAV1 CHD6 MAP3K21 AGAP1	3.50e-04	744	131	14	int:HDAC4
Interaction	RHOB interactions	TNIK PRKD2 KIF26B IQSEC2 DAB2 GPRIN1 TENM2 AKAP12 MPRIP USP31 ABLIM1 IQSEC1 COBL MAP3K21 DCUN1D3	3.72e-04	840	131	15	int:RHOB
Interaction	GABARAP interactions	AMFR BIRC6 NCOR1 RESF1 MTMR14 WDFY3	3.74e-04	145	131	6	int:GABARAP
Interaction	RCOR1 interactions	TNIK CENPF VPS4B ATG2B DVL3 BIRC6 LUZP1 NCOR1 MSH6 RESF1 CHD6	3.87e-04	494	131	11	int:RCOR1
Interaction	MAPKAP1 interactions	KIF13B DENND1A USP21 NAV1 MAP3K21 AGAP1	3.88e-04	146	131	6	int:MAPKAP1
Interaction	MAGI1 interactions	KIF13B DENND1A USP21 NAV1 MAP3K21 AGAP1	4.02e-04	147	131	6	int:MAGI1
Interaction	KALRN interactions	TNIK IQSEC2 GPRIN1 IQSEC1 AGAP2	4.09e-04	96	131	5	int:KALRN
Interaction	PHF21A interactions	CENPF VPS4B ATG2B DVL3 BIRC6 LUZP1 RESF1 NAV1 CHD6	4.14e-04	343	131	9	int:PHF21A
Interaction	WWTR1 interactions	ATG2B DVL3 GPRIN1 LUZP1 MPRIP NCOR1 MSH6 ABLIM1 GTF3C1 CEBPZ	4.42e-04	422	131	10	int:WWTR1
GeneFamily	Zinc fingers CW-type	MORC1 MORC2	4.00e-04	7	80	2	96
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF13B KIF27 KIF26B	1.10e-03	46	80	3	622
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	DMTF1 NCOR1 CHD6	1.67e-03	53	80	3	532
GeneFamily	Ubiquitin specific peptidases	USP43 USP21 USP31	1.95e-03	56	80	3	366
GeneFamily	X-linked mental retardation\|Rho GTPase activating proteins\|BAR-PH domain containing	AGAP1 AGAP2	2.52e-03	17	80	2	1291
GeneFamily	CD molecules\|Mucins	MUC19 MUC16	3.84e-03	21	80	2	648
GeneFamily	DNA polymerases	POLD1 POLE	4.61e-03	23	80	2	535
GeneFamily	Mitogen-activated protein kinase kinase kinases\|RAF family	MAP3K12 MAP3K21	5.01e-03	24	80	2	654
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PCLO MUC16 CRACR2B ABLIM1 CLMN KIAA1217 COBL RASEF AGAP1	8.38e-09	200	131	9	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MACC1 PCLO ABLIM1 ACOT11 CLMN KIAA1958 COBL MAP3K21	1.14e-07	194	131	8	5eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD4+_Memory_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	TNIK TSHZ2 UBASH3A CDC14A MPRIP ABLIM1 RESF1 SEPTIN1	1.18e-07	195	131	8	22191d361af136942508f1553ff41a626ed982ad
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_3\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	MACC1 KIF26B PCLO MUC16 WNT4 SLC9A2 RASEF	8.55e-07	174	131	7	9e5fae9ecc7c0111fc8a252e72b89dc89c0d3a7c
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MACC1 TSHZ2 MUC16 ABLIM1 SGSM2 KIAA1217 RASEF	1.03e-06	179	131	7	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DCHS2 TSHZ2 KIF26B FBN1 LOXHD1 KIAA1217 DAAM2	1.54e-06	190	131	7	2306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DCHS2 TSHZ2 KIF26B FBN1 LOXHD1 KIAA1217 DAAM2	1.54e-06	190	131	7	1f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DCHS2 TSHZ2 KIF26B FBN1 LOXHD1 KIAA1217 DAAM2	1.59e-06	191	131	7	a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DCHS2 TSHZ2 KIF26B FBN1 LOXHD1 KIAA1217 DAAM2	1.65e-06	192	131	7	9093a9e94a25682d109a7f6edc256a25a61103a0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DCHS2 TSHZ2 KIF26B FBN1 LOXHD1 KIAA1217 DAAM2	1.65e-06	192	131	7	9ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MACC1 PCLO ABLIM1 ACOT11 KIAA1958 COBL MAP3K21	1.77e-06	194	131	7	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	COVID_non-vent-Lymphocytic-T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	TNIK TSHZ2 UBASH3A CDC14A MPRIP ABLIM1 RESF1	1.83e-06	195	131	7	4bdedd924564a260841a9153604026b57487c83d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MACC1 PCLO ABLIM1 ACOT11 KIAA1958 COBL MAP3K21	1.89e-06	196	131	7	6ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1E MUC16 CRACR2B ABLIM1 CLMN COBL RASEF	2.16e-06	200	131	7	c450a15e21fa72d071ed6e3b9f22de557a0f3cea
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1E MUC16 CRACR2B ACOT11 CLMN COBL RASEF	2.16e-06	200	131	7	ed093626a9cac7531a2bf02f6e345c5e84b8c060
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1E MUC16 CRACR2B ACOT11 KIAA1217 COBL RASEF	2.16e-06	200	131	7	85c0f038bcfb42669dca2b80273b0f8a1421405e
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	SZT2 TBC1D5 RESF1 ACOT11 MAP3K21 CFAP44	9.84e-06	166	131	6	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Sgol2a_(Very_small_cluster)\|Striatum / BrainAtlas - Mouse McCarroll V32	AMFR SYT9 BIRC6 TRIP11 STRADA CFAP44	1.09e-05	169	131	6	c3bf0cb67f200d02d5a021754e9b2a68d23ea168
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Sgol2a_(Very_small_cluster)--\|Striatum / BrainAtlas - Mouse McCarroll V32	AMFR SYT9 BIRC6 TRIP11 STRADA CFAP44	1.09e-05	169	131	6	5375eb52ebadccb7bfff997a11985f23e81014d6
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Sgol2a_(Very_small_cluster)-\|Striatum / BrainAtlas - Mouse McCarroll V32	AMFR SYT9 BIRC6 TRIP11 STRADA CFAP44	1.09e-05	169	131	6	1c132d21255f5a5174ac38db4e91927f9093418e
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SZT2 IQSEC2 RUSC1 ABLIM1 IQSEC1 VWA3B	1.13e-05	170	131	6	55fe16d98ea284d05fb899888e4569c685644c7b
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRDM2 PIKFYVE RESF1 NETO1 ZBTB10 STAG3	1.82e-05	185	131	6	e913c64f9b4873443d88dce270f0b7b6d1b4cbce
ToppCell	ILEUM-inflamed-(7)_Lymphatics\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	TSHZ2 PCLO CRACR2B AKAP12 USP31 KIAA1217	1.82e-05	185	131	6	d711dd2e91cfee723dae1ccb2b910b8cf3becc3b
ToppCell	Control-Epithelial-Club\|Epithelial / Disease state, Lineage and Cell class	MACC1 CRACR2B FBN1 KIAA1217 FGF12 CHD6	1.82e-05	185	131	6	6814b3c94c7558443c038a227b5c8563d2cfeac4
ToppCell	wk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	POLE PEG3 MORC2 TFB1M SGSM2 MAP3K21	1.82e-05	185	131	6	636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TNIK MACC1 DENND1A AKAP12 WDFY3 AGAP1	1.93e-05	187	131	6	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCLO PEG3 WNT4 TENM2 ACOT11 NAV1	1.99e-05	188	131	6	a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TNIK MACC1 SYT9 SLC9A2 FGF12 MAP3K21	2.24e-05	192	131	6	0bb06738e1c3ec0c044a7ee61f6cf1d4781fb53c
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNIK TSHZ2 UBASH3A CDC14A MPRIP ABLIM1	2.24e-05	192	131	6	7ab626a516b07d899175ff12f1c8257688324e4b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PCLO ABLIM1 ACOT11 CLMN KIAA1958 COBL	2.31e-05	193	131	6	82e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TNIK MACC1 ABLIM1 KIAA1958 COBL AGAP1	2.38e-05	194	131	6	7002937e8903e037332a215d00fbc7c7843b33f2
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TSHZ2 KIF26B AKAP12 FBN1 LOXHD1 DAAM2	2.38e-05	194	131	6	240d122dcb9dd1ab2867503ad85869853adcacae
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TSHZ2 KIF26B AKAP12 FBN1 LOXHD1 DAAM2	2.38e-05	194	131	6	ae7df037592f1c20c9d32be15fe6fc3c562ebeb1
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TSHZ2 AKAP12 FBN1 LOXHD1 KIAA1217 DAAM2	2.45e-05	195	131	6	803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TSHZ2 KIF26B AKAP12 FBN1 LOXHD1 DAAM2	2.45e-05	195	131	6	44d7bef5f59c2c2bad1392ee6aabdaa5d7f531d9
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TSHZ2 AKAP12 FBN1 LOXHD1 KIAA1217 DAAM2	2.45e-05	195	131	6	4f70157d42a16ff0259bc24a62803c4df4285c44
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TSHZ2 KIF26B AKAP12 FBN1 LOXHD1 DAAM2	2.52e-05	196	131	6	ba869f7a86f37fd6d84d6ad69baca0e0faaf5887
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TSHZ2 KIF26B AKAP12 FBN1 LOXHD1 DAAM2	2.52e-05	196	131	6	30ad56d49000e4ddce73b4443b3994564bd1e2d6
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Penk_Col27a1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MACC1 KIF27 LOXHD1 NEUROG2	2.58e-05	58	131	4	ee9038695d11a428dc222962721bfdf11dd6954f
ToppCell	saliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	USP43 CRACR2B KIAA1217 COBL RASEF CHD6	2.59e-05	197	131	6	d6c9da7a3a6d2bcb13e2fc6605c8a59e7fb121c5
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TSHZ2 PEG3 WNT4 AKAP12 IER2 OLFM2	2.59e-05	197	131	6	05e303fff86db31f7b742324c64980eb2b9cff9a
ToppCell	saliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	USP43 CRACR2B KIAA1217 COBL RASEF CHD6	2.59e-05	197	131	6	80b05c8ad9c1edc5dea3236079372475431343fe
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TSHZ2 TENM2 USP31 ACOT11 CLMN KIAA1217	2.59e-05	197	131	6	1e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TSHZ2 KIF26B FBN1 LOXHD1 KIAA1217 DAAM2	2.59e-05	197	131	6	b349f8e96d61a4c296af64711e11fc44459a9413
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-F\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	UAP1 TSHZ2 AKAP12 ABLIM1 FBN1 NAV1	2.59e-05	197	131	6	fbff2fb7a8142b88c9dc71aa10980f4350b7e081
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TSHZ2 KIF26B FBN1 LOXHD1 KIAA1217 DAAM2	2.59e-05	197	131	6	c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCell	moderate-Epithelial-Secretory\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	MACC1 UAP1 TSHZ2 MUC16 CRACR2B ABLIM1	2.67e-05	198	131	6	7d96d7105a849c7280ce87bd76ce130ac47384fd
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TSHZ2 PEG3 WNT4 AKAP12 IER2 OLFM2	2.67e-05	198	131	6	cfe2d52b19a1b4c2c2076fa1d5a69baf21a49623
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TSHZ2 WNT4 TENM2 LUZP1 USP31 KIAA1217	2.67e-05	198	131	6	fc00cb25cdc6c31b7f9d397bc9f9a8f4e9708003
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MACC1 TSHZ2 MUC16 ABLIM1 CLMN CFAP44	2.67e-05	198	131	6	d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCell	356C-Fibroblasts-Fibroblast-F-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	UAP1 DAB2 AKAP12 ABLIM1 FBN1 NAV1	2.74e-05	199	131	6	beca4c7eb29ac771fd37f30cd23d4dce4afcfff8
ToppCell	356C-Fibroblasts-Fibroblast-F\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	UAP1 DAB2 AKAP12 ABLIM1 FBN1 NAV1	2.74e-05	199	131	6	cd3ab9a75b40e0d417d53b3d8756fc9bed30ac83
ToppCell	normal_Lung-Fibroblasts-COL14A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	UAP1 TSHZ2 AKAP12 IER2 ABLIM1 FBN1	2.82e-05	200	131	6	6d8f6a6b3f61c529fbed1376659641030abf4f2c
ToppCell	Neuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_2-SLC17A7_IL15-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	DCHS2 DAB2 CDC14A KIAA1217 RASEF NEUROG2	2.82e-05	200	131	6	48fd48990a6833066be314dc5b66b90893f7ea8f
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-CD4+_T_activated\|COVID-19_Mild / Disease, condition lineage and cell class	PDE9A TSHZ2 UBASH3A CDC14A MPRIP ABLIM1	2.82e-05	200	131	6	d9e8a0d047d4403fb7265fde7448e23a7780785c
ToppCell	Neuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_2-SLC17A7_IL15--L5-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	DCHS2 DAB2 CDC14A KIAA1217 RASEF NEUROG2	2.82e-05	200	131	6	9103e6f72a04f66f2b7069b0d71a719e9b10026b
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MUC16 CRACR2B ABLIM1 KIAA1217 COBL RASEF	2.82e-05	200	131	6	0eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCell	Neuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_2-SLC17A7_IL15\|Neuronal / cells hierarchy compared to all cells using T-Statistic	DCHS2 DAB2 CDC14A KIAA1217 RASEF NEUROG2	2.82e-05	200	131	6	e5e97767beb4413e87c9817a60a5f1ee5209198a
ToppCell	RV-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	TENM2 IRX4 ABLIM1 ACOT11 FGF12	3.06e-05	122	131	5	1cb1dd03b2aaedbe04f3ed907568c3b7f54767b3
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Cervical_Squamous_Cell_Carcinoma\|TCGA-Cervix / Sample_Type by Project: Shred V9	NDST1 CARMIL2 POLD1 MORC2 USP21	4.30e-05	131	131	5	88b3298110bc2333ffa202a3f41ac0d24e2308c7
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNIK TSHZ2 CDC14A ABLIM1 OLFM2	7.43e-05	147	131	5	463af96748349c8fec2911b353a7e7e4cb072280
ToppCell	368C-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	AMFR POLE KIAA1217 FGF12 WDR24	9.84e-05	156	131	5	4877aabf647238c0279e497345b6a6d5ee07ef9c
ToppCell	368C-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	AMFR POLE KIAA1217 FGF12 WDR24	9.84e-05	156	131	5	1d681fa17e62815f5d5f90c86be3c248b38e011b
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PEG3 USP43 TENM2 THAP4 ACOT11	1.01e-04	157	131	5	1f21d78a467fe22c5ab75d0917b840c1ac93f32c
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MAGEL2 DAB2 SLC9A2 PROKR2 DAAM2	1.11e-04	160	131	5	dd16ca90feb3ae88b6409d6c278b4765da565514
ToppCell	Influenza_Severe-Neutrophil\|Influenza_Severe / Disease group and Cell class	CACNA1E IER2 RESF1 DAAM2 WDFY3	1.14e-04	161	131	5	98c95b1b85d5427415af2ca8fb14849e97f6e8b5
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	SRSF4 SZT2 CDC14A CARD8 EVI5	1.17e-04	162	131	5	810881210e015c788814e4fe8d7a24c929cf2621
ToppCell	facs-Marrow-KLS-24m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAB2 WNT4 STK32C MAP3K12 DCUN1D3	1.21e-04	163	131	5	b83a35c4426d66b5734a98fa6c72b345fe462030
ToppCell	facs-Marrow-KLS-24m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAB2 WNT4 STK32C MAP3K12 DCUN1D3	1.21e-04	163	131	5	c20ca9b6b4170ebcb0e66eef3e5d8ebff22b1a91
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TMEM201 TSHZ2 KIF26B DAB2 STK32C	1.28e-04	165	131	5	50a8513d8d2630861499393a7f102b35366bad37
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DCHS2 TSHZ2 KIF26B MUC19 LSM11	1.32e-04	166	131	5	c11dcf9705b85ac3da6ae86358f5ffd64ae8327e
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-9\|TCGA-Brain / Sample_Type by Project: Shred V9	TNIK CDC14A ABLIM1 VPS13D DAAM2	1.35e-04	167	131	5	013971700e80b71e4b8c79b8fff0d8beeac295c3
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL2 UBASH3A ABLIM1 SYCP2 FAM199X	1.39e-04	168	131	5	182f08106ac65ea501e2fb9139d3b44b7c4662c9
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCHS2 DAB2 CDC14A KIAA1217 RASEF	1.39e-04	168	131	5	217770a94ace446cdfc7687b459dece707576e76
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CACNA1E CENPF UBASH3A THAP4 AGAP2	1.43e-04	169	131	5	c8691c4f707d46b2865fe46eabe24ea4d03c7b43
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_SLITRK6\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCHS2 PDE9A DAB2 KIAA1217 NEUROG2	1.43e-04	169	131	5	1c9e54e7b14eb99996590fb93b257cf881a9f184
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PEG3 SYT9 SLC9A2 RASEF SOWAHB	1.43e-04	169	131	5	d382a76d85875663502cc7dde2e3e0682605768e
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_ETV4\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCHS2 PDE9A TSHZ2 DAB2 KIAA1217	1.43e-04	169	131	5	716e9d4c5fb99c56b76afaa5ed90bfa859fde802
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_TBC1D26\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCHS2 DAB2 CDC14A KIAA1217 RASEF	1.43e-04	169	131	5	2abdd8ae9a5d88aac30992142d1b502c959bc015
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCHS2 DAB2 PROKR2 KIAA1217 RASEF	1.43e-04	169	131	5	0c341f91dc21aaf92bead18d59684d11510502ce
ToppCell	3'_v3-bone_marrow-Mast-Mast_cell_lympho\|bone_marrow / Manually curated celltypes from each tissue	MACC1 ATG2B AKAP12 MAP3K21 DCUN1D3	1.47e-04	170	131	5	4dedf482cd4521b3f87d2b5ae80f7a3ea8686a15
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MORC1 TNIK UBASH3A ABLIM1 SEPTIN1	1.51e-04	171	131	5	a8adce007ff4c713f71f2359b40cb3575b28c98d
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DCHS2 MUC16 CRACR2B SYCP2 KIAA1217	1.60e-04	173	131	5	464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CARMIL2 STK32C UBASH3A ABLIM1 SEPTIN1	1.64e-04	174	131	5	262d14b42bc5ec2c8d5f33a1a0eb49a8e38dd0f0
ToppCell	Adult-Epithelial-lung_goblet_cell-D231\|Adult / Lineage, Cell type, age group and donor	DCHS2 MUC16 CRACR2B SYCP2 KIAA1217	1.64e-04	174	131	5	7d2f802f493f19a068e097b2909a9000e2160266
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF13B TMEM201 WNT4 AKAP12 RUSC2	1.68e-04	175	131	5	31f0fb2e47e357dbf9c15436b7df85b3c370ded7
ToppCell	T_cells-Tph_and_Tfh\|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	TSHZ2 KIF26B EVI5 ZC2HC1A KIAA1217	1.73e-04	176	131	5	56c055488e34605d32562571a2fee621b47c9441
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCHS2 DAB2 CDC14A KIAA1217 RASEF	1.73e-04	176	131	5	ed421d8525108d2f585265d2cf777f07b29f44f0
ToppCell	Fetal_29-31_weeks-Epithelial-lung_goblet_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	UAP1 MUC16 CRACR2B SYCP2 RASEF	1.78e-04	177	131	5	a4c001a8e44142babf9f24dfe6f7b73a70b11b16
ToppCell	Fetal_29-31_weeks-Epithelial-lung_goblet_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	UAP1 MUC16 CRACR2B SYCP2 RASEF	1.78e-04	177	131	5	363e07b0f347f3716d530a28ead854b98e27d37c
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF13B PCLO PEG3 USP31 ACOT11	1.82e-04	178	131	5	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	Adult-Epithelial-lung_goblet_cell\|Adult / Lineage, Cell type, age group and donor	DCHS2 MUC16 CRACR2B SYCP2 KIAA1217	1.87e-04	179	131	5	1fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCell	FF-Differ-KC\|World / shred by cell class for mouse tongue	TNIK PDE9A KIF26B PCLO TENM2	1.87e-04	179	131	5	1526a130565a97c291a25a7a988089bffc1515c1
ToppCell	ILEUM-non-inflamed-(7)_Lymphatics\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	TSHZ2 PCLO CRACR2B AKAP12 USP31	1.87e-04	179	131	5	99777a8931356d1206b8ab22aaa1b1d5a600b809
ToppCell	Fetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	KIF26B LUZP1 USP31 ABLIM1 NAV1	1.92e-04	180	131	5	d8ef44710a77ad0fc03243428e5e1dc4d41200cb
ToppCell	RA-16._Neuronal\|RA / Chamber and Cluster_Paper	PDE9A CLMN KIAA1217 COBL DAAM2	1.92e-04	180	131	5	5842febfdabac61ce970254fb0ef17a628f1b8c0
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRDM2 PIKFYVE NETO1 ZBTB10 STAG3	1.97e-04	181	131	5	d66838fca0429cad2079cd8d92a5cd33eb0d3522
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MACC1 KIF26B SYT9 FGF12 MAP3K21	1.97e-04	181	131	5	b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCell	Globus_pallidus-Neuronal-Inhibitory\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MAGEL2 TENM2 IQSEC1 TACR3 SOWAHB	2.02e-04	182	131	5	04ccfa951eaa31fed6d140edb6c702d49363c5fa
ToppCell	Epithelial-lung_goblet_cell\|World / Lineage, Cell type, age group and donor	UAP1 MUC16 CRACR2B SYCP2 KIAA1217	2.07e-04	183	131	5	940cbe298e9c53b5622af09264586ed823d3141f
Drug	Mefloquine hydrochloride [51773-92-3]; Down 200; 9.6uM; PC3; HT_HG-U133A	TNIK ABCF3 MAP3K12 RUSC2 EVI5 ACOT11 SGSM2 COBL CABIN1	2.07e-06	196	131	9	5724_DN
Disease	cortical surface area measurement	TNIK PRKD2 DCHS2 KIF26B TBC1D5 WNT4 DENND1A TENM2 LUZP1 MPRIP EVI5 NCOR1 FBN1 RP1L1 MDC1 NAV1 FOXL2NB NEUROG2 AGAP1	5.63e-06	1345	128	19	EFO_0010736
Disease	neuroticism measurement, cognitive function measurement	CACNA1E KIF27 PCLO BIRC6 DENND1A SCAF1 GTF3C1 KIAA1217 NAV1 AGAP1	1.87e-04	566	128	10	EFO_0007660, EFO_0008354
Disease	pentachlorophenol measurement	TSHZ2 MUC16 CDC14A FGF12	2.92e-04	73	128	4	EFO_0022071
Disease	parathion measurement	TSHZ2 MUC16 CDC14A FGF12	2.92e-04	73	128	4	EFO_0022070
Disease	potassium chromate measurement	TSHZ2 MUC16 CDC14A FGF12	2.92e-04	73	128	4	EFO_0022072
Disease	mercuric chloride measurement	TSHZ2 MUC16 CDC14A FGF12	2.92e-04	73	128	4	EFO_0022068
Disease	heptachlor epoxide measurement	TSHZ2 MUC16 CDC14A FGF12	2.92e-04	73	128	4	EFO_0022067
Disease	methoxychlor measurement	TSHZ2 MUC16 CDC14A FGF12	2.92e-04	73	128	4	EFO_0022069
Disease	4,6-dinitro-o-cresol measurement	TSHZ2 MUC16 CDC14A FGF12	2.92e-04	73	128	4	EFO_0022053
Disease	2,4,5-trichlorophenol measurement	TSHZ2 MUC16 CDC14A FGF12	2.92e-04	73	128	4	EFO_0022052
Disease	azinphos methyl measurement	TSHZ2 MUC16 CDC14A FGF12	2.92e-04	73	128	4	EFO_0022055
Disease	aldrin measurement	TSHZ2 MUC16 CDC14A FGF12	2.92e-04	73	128	4	EFO_0022054
Disease	dicofol measurement	TSHZ2 MUC16 CDC14A FGF12	2.92e-04	73	128	4	EFO_0022060
Disease	disulfoton measurement	TSHZ2 MUC16 CDC14A FGF12	2.92e-04	73	128	4	EFO_0022062
Disease	dieldrin measurement	TSHZ2 MUC16 CDC14A FGF12	2.92e-04	73	128	4	EFO_0022061
Disease	endrin measurement	TSHZ2 MUC16 CDC14A FGF12	2.92e-04	73	128	4	EFO_0022064
Disease	endosulfan measurement	TSHZ2 MUC16 CDC14A FGF12	2.92e-04	73	128	4	EFO_0022063
Disease	heptachlor measurement	TSHZ2 MUC16 CDC14A FGF12	2.92e-04	73	128	4	EFO_0022066
Disease	ethion measurement	TSHZ2 MUC16 CDC14A FGF12	2.92e-04	73	128	4	EFO_0022065
Disease	chlorpyrifos measurement	TSHZ2 MUC16 CDC14A FGF12	2.92e-04	73	128	4	EFO_0022057
Disease	cadmium chloride measurement	TSHZ2 MUC16 CDC14A FGF12	2.92e-04	73	128	4	EFO_0022056
Disease	diazinon measurement	TSHZ2 MUC16 CDC14A FGF12	2.92e-04	73	128	4	EFO_0022059
Disease	dibutyl phthalate measurement	TSHZ2 MUC16 CDC14A FGF12	2.92e-04	73	128	4	EFO_0022058
Disease	environmental exposure measurement	TSHZ2 MUC16 CDC14A FGF12	2.92e-04	73	128	4	EFO_0008360
Disease	DDT metabolite measurement	TSHZ2 MUC16 CDC14A FGF12	3.07e-04	74	128	4	EFO_0007886
Disease	risk-taking behaviour	CACNA1E CAAP1 TSHZ2 TBC1D5 STK32C BIRC6 DENND1A TENM2 MSH6 RP1L1 ZBTB10	5.11e-04	764	128	11	EFO_0008579
Disease	ovarian cancer (implicated_via_orthology)	POLE MSH6	5.14e-04	8	128	2	DOID:2394 (implicated_via_orthology)
Disease	unipolar depression, bipolar disorder	DMTF1 CACNA1E PCLO DENND1A TENM2	6.08e-04	156	128	5	EFO_0003761, MONDO_0004985
Disease	brain measurement, neuroimaging measurement	TNIK DCHS2 ABCF3 KIF26B TBC1D5 LUZP1 SBNO1 FOXL2NB NEUROG2	6.82e-04	550	128	9	EFO_0004346, EFO_0004464
Disease	neuroimaging measurement	TNIK DCHS2 SZT2 KIF26B TBC1D5 DENND1A LUZP1 NCOR1 ABLIM1 SBNO1 FOXL2NB NEUROG2 AGAP1	7.79e-04	1069	128	13	EFO_0004346
Disease	venous thromboembolism	DCHS2 CAAP1 KIF26B TBC1D5 IER2 SBNO1 CLMN MAP3K21	9.20e-04	460	128	8	EFO_0004286
Disease	blood cobalt measurement	TSHZ2 MUC16 CDC14A FGF12	9.97e-04	101	128	4	EFO_0007577
Disease	polybrominated biphenyl measurement, gestational serum measurement, fetal genotype effect measurement, polybrominated diphenyl ether measurement	TBC1D5 LOXHD1	1.00e-03	11	128	2	EFO_0007959, EFO_0007961, EFO_0007962, EFO_0007964
Disease	motor function measurement	TSHZ2 IQSEC1	1.00e-03	11	128	2	EFO_0010749
Disease	insulin measurement	CACNA1E CAAP1 TBC1D5 SGSM2 COBL CHD6	1.12e-03	267	128	6	EFO_0004467
Disease	taurodeoxycholate measurement	CDC14A BRD8	1.20e-03	12	128	2	EFO_0010539
Disease	mismatch repair cancer syndrome (is_implicated_in)	POLE MSH6	1.20e-03	12	128	2	DOID:0112182 (is_implicated_in)
Disease	overall survival, pancreatic carcinoma	BRD8 ACOT11 IQSEC1	1.27e-03	49	128	3	EFO_0000638, EFO_0002618
Disease	pulse pressure measurement, social deprivation	TBC1D5 FBN1	1.64e-03	14	128	2	EFO_0005763, EFO_0009696
Disease	blood nickel measurement	TSHZ2 MUC16 CDC14A FGF12	1.88e-03	120	128	4	EFO_0007583
Disease	Hypogonadotropic hypogonadism	POLD1 TACR3	1.89e-03	15	128	2	C0271623
Disease	Primary hypogonadism	POLD1 TACR3	1.89e-03	15	128	2	C0948896
Disease	Hypogonadism, Isolated Hypogonadotropic	POLD1 TACR3	1.89e-03	15	128	2	C3489396
Disease	Hypogonadism	POLD1 TACR3	2.15e-03	16	128	2	C0020619
Disease	Malignant neoplasm of endometrium	POLE MSH6	2.73e-03	18	128	2	C0007103
Disease	Carcinoma in situ of endometrium	POLE MSH6	2.73e-03	18	128	2	C0346191
Disease	Bladder Neoplasm	AMFR PRDM2 NCOR1 CHD6	3.29e-03	140	128	4	C0005695
Disease	cortical thickness	TNIK ABCF3 TBC1D5 DENND1A TENM2 LUZP1 VPS13D FBN1 NAV1 FOXL2NB NEUROG2 AGAP1	3.36e-03	1113	128	12	EFO_0004840
Disease	Deaf Mutism	POLD1 CDC14A	3.37e-03	20	128	2	C4082305
Disease	citrulline measurement	KIF26B RP1L1	3.37e-03	20	128	2	EFO_0009777
Disease	Deafness, Acquired	POLD1 CDC14A	3.37e-03	20	128	2	C0751068
Disease	Hearing Loss, Extreme	POLD1 CDC14A	3.37e-03	20	128	2	C0086395
Disease	Complete Hearing Loss	POLD1 CDC14A	3.37e-03	20	128	2	C0581883
Disease	Prelingual Deafness	POLD1 CDC14A	3.37e-03	20	128	2	C0011052
Disease	Bilateral Deafness	POLD1 CDC14A	3.37e-03	20	128	2	C3665473
Disease	Malignant neoplasm of urinary bladder	AMFR PRDM2 NCOR1 CHD6	3.37e-03	141	128	4	C0005684
Disease	Colorectal Carcinoma	POLD1 POLE PEG3 SYT9 STK32C CDC14A AKAP12 MSH6 OLFM2	3.60e-03	702	128	9	C0009402
Disease	Endometrial Carcinoma	POLD1 POLE MSH6	3.82e-03	72	128	3	C0476089
Disease	colorectal carcinoma (is_implicated_in)	AKAP12 MSH6	4.07e-03	22	128	2	DOID:0080199 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
SKRRSNLFTSRKGSD	AGAP1	311	Q9UPQ3
QSLNRSSKGSSSLDR	BIRC6	2211	Q9NR09
VRTEGKESSSASRSR	CACNA1E	926	Q15878
VTSSERTSARGSNRK	ABLIM1	21	O14639
SAKSLRGRDSTRKQD	BRD8	826	Q9H0E9
GSSKKRARRGSSSDE	AKAP12	686	Q02952
ATAKRINRTSLSSGA	CDC14A	456	Q9UNH5
DASRNVFSRTKSRAA	CARMIL2	436	Q6F5E8
ASQAGSRKESRLESS	ABCF3	156	Q9NUQ8
RGLASVFSNRTSRKS	ACOT11	11	Q8WXI4
RTSLFANRRGSDSEK	AGAP2	646	Q99490
ANRRGSDSEKRSLDS	AGAP2	651	Q99490
RRKRSSQEAAAALAA	CAAP1	11	Q9H8G2
RSSDGKSSSQVNRSR	FLG	261	P20930
SGSRSASRQTRKDKQ	FLG	1211	P20930
SGSNRSGSDRRKEKD	DVL3	576	Q92997
AALGRSASSVKDRCR	DMTF1	251	Q9Y222
SRKDGDLTTRDSISR	CFAP44	1311	Q96MT7
GRESKSNAEESSLQR	DCUN1D3	76	Q8IWE4
AFQRRSKVDSSGRSS	ATG2B	1381	Q96BY7
RLRAADGSLSAKSFQ	OLFM2	106	O95897
KGSRSNLSTRDASIL	NETO1	441	Q8TDF5
RTDKDDSRSITNLTG	RASEF	711	Q8IZ41
DSGTRRKNATRETTS	IRX4	141	P78413
SFELSASRRGQKRNI	MORC1	611	Q86VD1
RGRRTAKSSANDLLA	DAB2	441	P98082
SRKRSGSQALEVTRE	DAAM2	1046	Q86T65
RASRLENGSDTSSKS	MUC16	1871	Q8WXI7
SPSSDTRQGRSEKRA	MPRIP	326	Q6WCQ1
QASAREESRSELSGR	LSM11	286	P83369
SQATRGRTDRSSVKT	MDC1	1471	Q14676
CRASSIDRRGSSKER	MAGEL2	721	Q9UJ55
SRARAVSRGAKTAET	NEUROG2	91	Q9H2A3
LRRKDRGSTTSLGSD	MTMR14	431	Q8NCE2
QRGKALQASSRLSES	FOXL2NB	21	Q6ZUU3
DLSDRSERGSLKRQS	IQSEC1	391	Q6DN90
SERGSLKRQSAYERS	IQSEC1	396	Q6DN90
KRGALSSSLRDLSDA	IQSEC2	1136	Q5JU85
SSSLRDLSDAGKRGR	IQSEC2	1141	Q5JU85
EKAQDAGSRRSSISS	KIF26B	1266	Q2KJY2
ESRNKNSLGRSERRT	KIAA1109	2651	Q2LD37
NSSRQRAFRKGTTDT	LOXHD1	1846	Q8IVV2
SASAAERIRDSKKRS	FAM199X	321	Q6PEV8
SEGQEKSGTRCRSRS	KIF27	651	Q86VH2
QRKRRTSVGSSSSDE	PCLO	1526	Q9Y6V0
VELSRTGGNRKRSSD	MUC19	396	Q7Z5P9
TSGATEKSRERSRDV	PDE9A	571	O76083
KSGDRTSRARRTSQE	FAM205C	56	A6NFA0
LETDSKSLRSVNGSR	EVI5	96	O60447
AGSDASSKLRALQNR	NDST1	736	P52848
NNCSGARKRRLSSTS	PRKD2	186	Q9BZL6
RDDGATSSVSALKRL	POLE	21	Q07864
ALSDANKASARASRE	MSH6	16	P52701
DVSRSSKSGRARESS	PEG3	321	Q9GZU2
SKSGRARESSDRSQR	PEG3	326	Q9GZU2
QSRADSRAKASEESL	MORC2	966	Q9Y6X9
SGTLKTSNTLDREAR	DCHS2	1986	Q6V1P9
DLSSQKRETLRGADS	PIKFYVE	1756	Q9Y2I7
RTRKASAEEANFRGS	CEFIP	811	Q711Q0
GRSFSSRLQDSRSLD	BORCS6	156	Q96GS4
SGETAKRRSARVRNT	CABIN1	386	Q9Y6J0
RSTLQIGKRDANSSF	CENPF	256	P49454
KRTFRQRAADSSDSD	GCFC2	6	P16383
ESTESTDSQKRRSGR	CHD6	226	Q8TD26
RGRKRRSTNETDASN	FBN1	2726	P35555
LSRLSKASSRARSDD	GJA8	416	P48165
NRRETFRKSSLGNDE	COBL	226	O75128
EARRAGSSCRKALTT	CRACR2B	356	Q8N4Y2
DSGSSRNIDASKLIR	CARD8	21	Q9Y2G2
RTRRSASQAGSKSQA	CENPV	41	Q7Z7K6
SRKSSSIGNFNEREL	BPIFB6	386	Q8NFQ5
RAAVTRSQKRGISSE	MAP3K12	706	Q12852
ALASSRRSSSEGLSK	LUZP1	566	Q86V48
SRNSGRSKSVSELLD	MACC1	131	Q6ZN28
LARSSARAAETKQGL	DENND1A	926	Q8TEH3
SSSSRQLDRKALGSA	GPRIN1	721	Q7Z2K8
AASSGISLQADRRAK	SBNO1	941	A3KN83
IRDSSFQSKQTGRRD	POLD1	431	P28340
EQLSSGNKDSRDRRL	CEBPZ	316	Q03701
AIEEERASARSKRSS	PRDM2	151	Q13029
AKVSRKRRSSSLSDG	IER2	116	Q9BTL4
RSSSDAGRDRLSDAK	NAV1	576	Q8NEY1
ARESNSDRVSASKRR	FGF12	16	P61328
ASSLDANRKRGSLLS	KIF13B	721	Q9NQT8
RLAQSLRGTSKEAAS	RUSC1	701	Q9BVN2
GTARSIDSTKSRSRD	RUSC2	76	Q8N2Y8
RSLDNDDGRRSNSKA	SYT9	206	Q86SS6
LRNGSLETKSSAGRA	SZT2	2406	Q5T011
GDTRRKTNDASSESI	STRADA	36	Q7RTN6
SVSRGRSQEKSLRQS	SRSF4	316	Q08170
SSNDAAQVGKSSRSR	TATDN2	401	Q93075
SSGRSCRNERSIQEK	SMG5	631	Q9UPR3
EGIFQRASKSRRSAS	MAP3K21	761	Q5TCX8
DNVNSRLSKRSFSAD	RESF1	1696	Q9HCM1
IASDKDARERGSQSS	NCOR1	1941	O75376
RKRHSSGSASEDRLA	SGSM2	226	O43147
RRTKERLSNGNSRGS	KIAA1217	41	Q5T5P2
AERLAANTGSKQRSR	TFB1M	181	Q8WVM0
IKSRRSSGLSSRENS	TENM2	136	Q9NT68
GRDRANSTQSRLSKR	WDR20	341	Q8TBZ3
NDADTTRSSRKKRAT	TACR3	416	P29371
QRLASRVNVRDSSGK	SOWAHB	691	A6NEL2
RLAKNKSRDNSRDSS	STK32C	401	Q86UX6
ARGSRFSKSADERQR	AMFR	566	Q9UKV5
ENRSNSAARDKASRL	APOL5	191	Q9BWW9
SILSSRKENGRSNSL	CLMN	406	Q96JQ2
RNRILTRKANSSGEA	CLMN	941	Q96JQ2
AESRVLSNRGDSLSR	TRIP10	471	Q15642
GARDRASRSKLSRQS	SEPTIN1	306	Q8WYJ6
GSRSENESEAARRIK	VPS4B	241	O75351
TSQSESSDLAGRLKR	UHRF1BP1L	751	A0JNW5
QAGSSERTRVRANSK	TNIK	751	Q9UKE5
GNSKDSRRGTSELDR	USP43	976	Q70EL4
TNLARSKSVSSGDLR	USP21	106	Q9UK80
EIRRRASNKSTEAAS	WDFY3	91	Q8IZQ1
QRAVGDTKRALSASS	STAG3	6	Q9UJ98
KNARRSEAETLSGLT	RP1L1	231	Q8IWN7
QKRRTISIADGNSSD	SLC9A2	681	Q9UBY0
TRNSKLNRGSLSLDD	SNX14	476	Q9Y5W7
SSQKDRRRSGAASSS	SCAF1	746	Q9H7N4
LAASRRGSSSRDKDR	SPATA20	21	Q8TB22
RGSSSRDKDRSATVS	SPATA20	26	Q8TB22
NRVDNAASLKSRSSE	SYCP2	531	Q9BX26
QRGSKSSADLDLRTN	PROKR2	356	Q8NFJ6
RSKLERGSACSNRSI	TMEM201	591	Q5SNT2
SRSDSSGEKRQLDVS	TTLL6	766	Q8N841
KLSNSERRNCDTRNG	TSHZ2	146	Q9NRE2
EISLATAQKRSSDGR	UAP1	306	Q16222
RKTFDSSRQRAEGTD	ZC2HC1A	46	Q96GY0
KDTAESRSGRRTDVN	TRIP11	1906	Q15643
DVRERSKGASSSRAL	WNT4	171	P56705
RSLKNAGSRSSSREN	TEX33	91	O43247
NRDGLSSSRDQKIAS	ZBTB10	486	Q96DT7
NKNGRRTSSTLDSEG	TBC1D5	36	Q92609
SALRQKETRRSTDLG	USP31	1231	Q70CQ4
ERKDGLSNASSRRTA	VWA3B	791	Q502W6
LSNASSRRTALSDKE	VWA3B	796	Q502W6
SETRLDRSKGDARSD	WDR24	496	Q96S15
TNDSSALSKRSLAAR	LCMT2	16	O60294
EEERSSSKRRGRGSQ	GTF3C1	481	Q12789
GELKSLRQRVSRSDS	THAP4	371	Q8WY91
ATDLNSRKDGEASSR	UBASH3A	356	P57075
LTNTQDNSRRKSRDG	VPS13D	741	Q5THJ4
DNSRRKSRDGSASEE	VPS13D	746	Q5THJ4
ARTDSVKRESRSGST	KIAA1958	596	Q8N8K9