Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase I general transcription initiation factor activity	UBTF UBTFL1	1.33e-04	9	39	2	GO:0001181
GeneOntologyMolecularFunction	RNA polymerase I core promoter sequence-specific DNA binding	UBTF UBTFL1	2.02e-04	11	39	2	GO:0001164
GeneOntologyMolecularFunction	RNA polymerase I transcription regulatory region sequence-specific DNA binding	UBTF UBTFL1	2.86e-04	13	39	2	GO:0001163
GeneOntologyMolecularFunction	general transcription initiation factor activity	BRF1 UBTF UBTFL1	3.16e-04	68	39	3	GO:0140223
GeneOntologyMolecularFunction	C2H2 zinc finger domain binding	GATA2 GATA1	4.96e-04	17	39	2	GO:0070742
GeneOntologyBiologicalProcess	eosinophil fate commitment	GATA2 GATA1	3.67e-06	2	40	2	GO:0035854
GeneOntologyBiologicalProcess	regulation of primitive erythrocyte differentiation	GATA2 GATA1	1.10e-05	3	40	2	GO:0010725
GeneOntologyBiologicalProcess	positive regulation of erythrocyte differentiation	GATA2 ABCB10 GATA1	5.02e-05	37	40	3	GO:0045648
GeneOntologyBiologicalProcess	eosinophil differentiation	GATA2 GATA1	7.65e-05	7	40	2	GO:0030222
GeneOntologyBiologicalProcess	primitive erythrocyte differentiation	GATA2 GATA1	1.02e-04	8	40	2	GO:0060319
GeneOntologyBiologicalProcess	exocytosis	GATA2 ARFGEF1 RIMBP2 SYTL5 SACM1L GATA1	1.76e-04	434	40	6	GO:0006887
GeneOntologyBiologicalProcess	RNA polymerase I preinitiation complex assembly	UBTF UBTFL1	1.99e-04	11	40	2	GO:0001188
GeneOntologyBiologicalProcess	regulation of erythrocyte differentiation	GATA2 ABCB10 GATA1	2.14e-04	60	40	3	GO:0045646
GeneOntologyBiologicalProcess	primitive hemopoiesis	GATA2 GATA1	2.39e-04	12	40	2	GO:0060215
GeneOntologyCellularComponent	nuclear RNA export factor complex	NXF2 NXF5	7.45e-05	7	40	2	GO:0042272
Domain	MRF_C1	MYRFL MYRF	4.25e-06	2	39	2	IPR026932
Domain	ICA	MYRFL MYRF	4.25e-06	2	39	2	PS51688
Domain	NDT80_DNA-bd_dom	MYRFL MYRF	4.25e-06	2	39	2	IPR024061
Domain	MRF_C2	MYRFL MYRF	4.25e-06	2	39	2	IPR025719
Domain	NDT80	MYRFL MYRF	4.25e-06	2	39	2	PS51517
Domain	MRF_C1	MYRFL MYRF	4.25e-06	2	39	2	PF13887
Domain	Peptidase_S74	MYRFL MYRF	4.25e-06	2	39	2	PF13884
Domain	S74_ICA	MYRFL MYRF	4.25e-06	2	39	2	IPR030392
Domain	NDT80_PhoG	MYRFL MYRF	4.25e-06	2	39	2	PF05224
Domain	MRF_C2	MYRFL MYRF	4.25e-06	2	39	2	PF13888
Domain	-	MYRFL MYRF	4.25e-06	2	39	2	2.60.40.1390
Domain	NXF_fam	NXF2 NXF5	1.27e-05	3	39	2	IPR030217
Domain	TF_GATA-2/3	GATA2 GATA1	1.27e-05	3	39	2	IPR016374
Domain	Tap_RNA_bd	NXF2 NXF5	2.54e-05	4	39	2	PD043466
Domain	Tap_RNA-bd	NXF2 NXF5	2.54e-05	4	39	2	IPR015245
Domain	Tap-RNA_bind	NXF2 NXF5	2.54e-05	4	39	2	PF09162
Domain	NTF2	NXF2 NXF5	1.52e-04	9	39	2	IPR002075
Domain	NTF2_DOMAIN	NXF2 NXF5	1.52e-04	9	39	2	PS50177
Domain	ZnF_GATA	GATA2 GATA1	2.77e-04	12	39	2	SM00401
Domain	-	NXF2 NXF5	3.27e-04	13	39	2	3.10.450.50
Domain	NTF2-like_dom	NXF2 NXF5	4.39e-04	15	39	2	IPR032710
Domain	Znf_GATA	GATA2 GATA1	4.39e-04	15	39	2	IPR000679
Domain	GATA	GATA2 GATA1	4.39e-04	15	39	2	PF00320
Domain	GATA_ZN_FINGER_1	GATA2 GATA1	5.01e-04	16	39	2	PS00344
Domain	GATA_ZN_FINGER_2	GATA2 GATA1	5.01e-04	16	39	2	PS50114
Domain	C2	WWC2 SYTL5 CAPN6	3.22e-03	142	39	3	PS50004
Domain	AAA+_ATPase	AK9 ABCB10 DYNC2H1	3.35e-03	144	39	3	IPR003593
Domain	AAA	AK9 ABCB10 DYNC2H1	3.35e-03	144	39	3	SM00382
Domain	-	WWC2 SYTL5 CAPN6	3.62e-03	148	39	3	2.60.40.150
Domain	C2_dom	WWC2 SYTL5 CAPN6	4.82e-03	164	39	3	IPR000008
Domain	HMG_box	UBTF UBTFL1	5.47e-03	53	39	2	PF00505
Domain	p53-like_TF_DNA-bd	MYRFL MYRF	5.47e-03	53	39	2	IPR008967
Domain	HMG_BOX_2	UBTF UBTFL1	5.68e-03	54	39	2	PS50118
Domain	HMG	UBTF UBTFL1	5.68e-03	54	39	2	SM00398
Domain	-	UBTF UBTFL1	5.88e-03	55	39	2	1.10.30.10
Domain	-	GATA2 GATA1	6.31e-03	57	39	2	3.30.50.10
Domain	Znf_NHR/GATA	GATA2 GATA1	6.52e-03	58	39	2	IPR013088
Domain	HMG_box_dom	UBTF UBTFL1	8.13e-03	65	39	2	IPR009071
Pubmed	Essential and instructive roles of GATA factors in eosinophil development.	GATA2 GATA1	1.29e-06	2	40	2	12045236
Pubmed	GATA-2 reinforces megakaryocyte development in the absence of GATA-1.	GATA2 GATA1	1.29e-06	2	40	2	19620289
Pubmed	Context-dependent GATA factor function: combinatorial requirements for transcriptional control in hematopoietic and endothelial cells.	GATA2 GATA1	1.29e-06	2	40	2	17347142
Pubmed	Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy.	GATA2 GATA1	1.29e-06	2	40	2	19941826
Pubmed	Common polymorphisms in LRP and A2M do not affect genetic risk for Alzheimer disease in Northern Ireland.	A2M PTPRA	1.29e-06	2	40	2	11496365
Pubmed	[Expression of GATA-1 and GATA-2 in the bone marrow of patients with Monge's disease].	GATA2 GATA1	1.29e-06	2	40	2	18078130
Pubmed	No association of three polymorphisms in the alpha-2-macroglobulin and lipoprotein related receptor genes with multiple sclerosis.	A2M PTPRA	1.29e-06	2	40	2	11498265
Pubmed	Decreased mRNA expression of GATA1 and GATA2 is associated with tumor aggressiveness and poor outcome in clear cell renal cell carcinoma.	GATA2 GATA1	1.29e-06	2	40	2	25230694
Pubmed	GATA factor switching from GATA2 to GATA1 contributes to erythroid differentiation.	GATA2 GATA1	1.29e-06	2	40	2	23911012
Pubmed	Progenitor stage-specific activity of a cis-acting double GATA motif for Gata1 gene expression.	GATA2 GATA1	1.29e-06	2	40	2	25535330
Pubmed	Overexpression of human GATA-1 and GATA-2 interferes with spine formation and produces depressive behavior in rats.	GATA2 GATA1	1.29e-06	2	40	2	25340772
Pubmed	Dynamic Control of Enhancer Repertoires Drives Lineage and Stage-Specific Transcription during Hematopoiesis.	GATA2 GATA1	1.29e-06	2	40	2	26766440
Pubmed	Roles of hematopoietic transcription factors GATA-1 and GATA-2 in the development of red blood cell lineage.	GATA2 GATA1	1.29e-06	2	40	2	12432220
Pubmed	Functional overlap of GATA-1 and GATA-2 in primitive hematopoietic development.	GATA2 GATA1	1.29e-06	2	40	2	14504093
Pubmed	Differential GATA factor stabilities: implications for chromatin occupancy by structurally similar transcription factors.	GATA2 GATA1	1.29e-06	2	40	2	18154321
Pubmed	Chromatin occupancy analysis reveals genome-wide GATA factor switching during hematopoiesis.	GATA2 GATA1	1.29e-06	2	40	2	22383799
Pubmed	GATA-1 and GATA-2 gene expression is related to the severity of dysplasia in myelodysplastic syndrome.	GATA2 GATA1	1.29e-06	2	40	2	12145700
Pubmed	GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling.	GATA2 GATA1	1.29e-06	2	40	2	12857954
Pubmed	GATA factor mutations in hematologic disease.	GATA2 GATA1	1.29e-06	2	40	2	28179280
Pubmed	GATA suppresses erythropoietin gene expression through GATA site in mouse erythropoietin gene promoter.	GATA2 GATA1	3.87e-06	3	40	2	12041667
Pubmed	GATA transcription factors are involved in IgE-dependent mast cell degranulation by enhancing the expression of phospholipase C-γ1.	GATA2 GATA1	3.87e-06	3	40	2	22390417
Pubmed	Molecular cloning and characterization of the GATA1 cofactor human FOG1 and assessment of its binding to GATA1 proteins carrying D218 substitutions.	GATA2 GATA1	3.87e-06	3	40	2	12483298
Pubmed	GATA transcription factors inhibit cytokine-dependent growth and survival of a hematopoietic cell line through the inhibition of STAT3 activity.	GATA2 GATA1	3.87e-06	3	40	2	15673499
Pubmed	GATA-1, -2 and -3 genes expression in bone marrow microenviroment with chronic aplastic anemia.	GATA2 GATA1	3.87e-06	3	40	2	17654061
Pubmed	Globin gene activation during haemopoiesis is driven by protein complexes nucleated by GATA-1 and GATA-2.	GATA2 GATA1	3.87e-06	3	40	2	15215894
Pubmed	Regulation of GATA factor expression is distinct between erythroid and mast cell lineages.	GATA2 GATA1	3.87e-06	3	40	2	22988301
Pubmed	An intron GATA-binding site regulates chromatin accessibility and is essential for IL-4 gene expression in mast cells.	GATA2 GATA1	3.87e-06	3	40	2	15739164
Pubmed	Antagonism of FOG-1 and GATA factors in fate choice for the mast cell lineage.	GATA2 GATA1	3.87e-06	3	40	2	18299398
Pubmed	Myrf guides target gene selection of transcription factor Sox10 during oligodendroglial development.	MYRFL MYRF	3.87e-06	3	40	2	31828317
Pubmed	Chromatin occupancy and epigenetic analysis reveal new insights into the function of the GATA1 N terminus in erythropoiesis.	GATA2 GATA1	3.87e-06	3	40	2	31409672
Pubmed	Molecular hallmarks of endogenous chromatin complexes containing master regulators of hematopoiesis.	GATA2 GATA1	3.87e-06	3	40	2	18779319
Pubmed	GATA factors are essential for transcription of the survival gene E4bp4 and the viability response of interleukin-3 in Ba/F3 hematopoietic cells.	GATA2 GATA1	3.87e-06	3	40	2	12023274
Pubmed	The upregulation of Gata transcription factors family and FOG-1 in expanded and differentiated cord blood-derived CD34+ hematopoietic stem cells to megakaryocyte lineage during co-culture with cord blood mesenchymal stem cells.	GATA2 GATA1	3.87e-06	3	40	2	35690555
Pubmed	Exchange of GATA factors mediates transitions in looped chromatin organization at a developmentally regulated gene locus.	GATA2 GATA1	3.87e-06	3	40	2	18243117
Pubmed	Dynamic regulation of Gata factor levels is more important than their identity.	GATA2 GATA1	3.87e-06	3	40	2	17327407
Pubmed	GATA-1 and GATA-2 binding to 3' enhancer of WT1 gene is essential for its transcription in acute leukemia and solid tumor cell lines.	GATA2 GATA1	3.87e-06	3	40	2	19212333
Pubmed	GATA-factor dependence of the multitype zinc-finger protein FOG-1 for its essential role in megakaryopoiesis.	GATA2 GATA1	3.87e-06	3	40	2	12077323
Pubmed	Graded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate.	GATA2 GATA1	3.87e-06	3	40	2	19491391
Pubmed	Transcription factor GATA1 is dispensable for mast cell differentiation in adult mice.	GATA2 GATA1	7.73e-06	4	40	2	24615013
Pubmed	Critical Roles for PU.1, GATA1, and GATA2 in the expression of human FcεRI on mast cells: PU.1 and GATA1 transactivate FCER1A, and GATA2 transactivates FCER1A and MS4A2.	GATA2 GATA1	7.73e-06	4	40	2	24639354
Pubmed	SENP1-mediated GATA1 deSUMOylation is critical for definitive erythropoiesis.	GATA2 GATA1	7.73e-06	4	40	2	20457756
Pubmed	Clinical significance of Gata-1, Gata-2, EKLF, and c-MPL expression in acute myeloid leukemia.	GATA2 GATA1	7.73e-06	4	40	2	19097174
Pubmed	Notch1-mediated signaling induces MHC class II expression through activation of class II transactivator promoter III in mast cells.	GATA2 GATA1	7.73e-06	4	40	2	21321116
Pubmed	Histone modifications silence the GATA transcription factor genes in ovarian cancer.	GATA2 GATA1	7.73e-06	4	40	2	16607277
Pubmed	Formation of a Tap/NXF1 homotypic complex is mediated through the amino-terminal domain of Tap and enhances interaction with nucleoporins.	NXF2 NXF5	1.29e-05	5	40	2	17978099
Pubmed	Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development.	GATA2 GATA1	1.29e-05	5	40	2	17962413
Pubmed	Fragile X mental retardation protein FMRP and the RNA export factor NXF2 associate with and destabilize Nxf1 mRNA in neuronal cells.	NXF2 NXF5	1.29e-05	5	40	2	17548835
Pubmed	NXF2 is involved in cytoplasmic mRNA dynamics through interactions with motor proteins.	NXF2 NXF5	1.29e-05	5	40	2	17403691
Pubmed	Mast cell IL-4 expression is regulated by Ikaros and influences encephalitogenic Th1 responses in EAE.	GATA2 GATA1	1.29e-05	5	40	2	16628252
Pubmed	Normal reproductive and macrophage function in Pem homeobox gene-deficient mice.	GATA2 GATA1	1.29e-05	5	40	2	9769172
Pubmed	An intricate regulatory circuit between FLI1 and GATA1/GATA2/LDB1/ERG dictates erythroid vs. megakaryocytic differentiation.	GATA2 GATA1	1.29e-05	5	40	2	38695236
Pubmed	GATA-binding transcription factors in mast cells regulate the promoter of the mast cell carboxypeptidase A gene.	GATA2 GATA1	1.29e-05	5	40	2	1744088
Pubmed	Association of erythroid transcription factors: complexes involving the LIM protein RBTN2 and the zinc-finger protein GATA1.	GATA2 GATA1	1.29e-05	5	40	2	7568177
Pubmed	Genetic risk factors of sporadic Alzheimer's disease among Chinese in Taiwan.	A2M PTPRA	1.29e-05	5	40	2	11099722
Pubmed	Gfi-1B promoter remains associated with active chromatin marks throughout erythroid differentiation of human primary progenitor cells.	GATA2 GATA1	1.93e-05	6	40	2	19522008
Pubmed	Initiation of murine embryonic erythropoiesis: a spatial analysis.	GATA2 GATA1	1.93e-05	6	40	2	9028937
Pubmed	Abundant expression of transcription factor GATA-2 in proliferating but not in differentiated mast cells in tissues of mice: demonstration by in situ hybridization.	GATA2 GATA1	1.93e-05	6	40	2	8562971
Pubmed	Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators.	GATA2 GATA1	1.93e-05	6	40	2	21571218
Pubmed	Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: functional antagonism in erythroid cells.	GATA2 GATA1	1.93e-05	6	40	2	10364157
Pubmed	Direct protein interactions are responsible for Ikaros-GATA and Ikaros-Cdk9 cooperativeness in hematopoietic cells.	GATA2 GATA1	1.93e-05	6	40	2	23732910
Pubmed	Defects of the heart, eye, and megakaryocytes in peroxisome proliferator activator receptor-binding protein (PBP) null embryos implicate GATA family of transcription factors.	GATA2 GATA1	2.70e-05	7	40	2	11724781
Pubmed	GATA factors and androgen receptor collaborate to transcriptionally activate the Rhox5 homeobox gene in Sertoli cells.	GATA2 GATA1	2.70e-05	7	40	2	18212046
Pubmed	Sox7-sustained expression alters the balance between proliferation and differentiation of hematopoietic progenitors at the onset of blood specification.	GATA2 GATA1	3.60e-05	8	40	2	19801444
Pubmed	Etv2/ER71 induces vascular mesoderm from Flk1+PDGFRα+ primitive mesoderm.	GATA2 GATA1	3.60e-05	8	40	2	21911838
Pubmed	Gata6 restricts Isl1 to the posterior of nascent hindlimb buds through Isl1 cis-regulatory modules.	GATA2 GATA1	3.60e-05	8	40	2	29197504
Pubmed	Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells.	GATA2 GATA1	4.62e-05	9	40	2	7926723
Pubmed	Mouse embryonic head as a site for hematopoietic stem cell development.	GATA2 GATA1	4.62e-05	9	40	2	23122290
Pubmed	Ikaros interacts with P-TEFb and cooperates with GATA-1 to enhance transcription elongation.	GATA2 GATA1	4.62e-05	9	40	2	21245044
Pubmed	NXF5, a novel member of the nuclear RNA export factor family, is lost in a male patient with a syndromic form of mental retardation.	NXF2 NXF5	4.62e-05	9	40	2	11566096
Pubmed	Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene.	GATA2 GATA1	4.62e-05	9	40	2	7624372
Pubmed	Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression.	GATA2 GATA1	5.77e-05	10	40	2	15889140
Pubmed	mTORC1 activity is essential for erythropoiesis and B cell lineage commitment.	GATA2 GATA1	7.05e-05	11	40	2	31729420
Pubmed	Immune-related zinc finger gene ZFAT is an essential transcriptional regulator for hematopoietic differentiation in blood islands.	GATA2 GATA1	7.05e-05	11	40	2	20660741
Pubmed	Nuclear export factor family protein participates in cytoplasmic mRNA trafficking.	NXF2 NXF5	7.05e-05	11	40	2	16014633
Pubmed	Thrombopoietin rescues in vitro erythroid colony formation from mouse embryos lacking the erythropoietin receptor.	GATA2 GATA1	7.05e-05	11	40	2	8799165
Pubmed	TAF10 Interacts with the GATA1 Transcription Factor and Controls Mouse Erythropoiesis.	GATA2 GATA1	8.45e-05	12	40	2	25870109
Pubmed	GATA-1 self-association controls erythroid development in vivo.	GATA2 GATA1	8.45e-05	12	40	2	17374603
Pubmed	A critical role for endoglin in the emergence of blood during embryonic development.	GATA2 GATA1	8.45e-05	12	40	2	22535663
Pubmed	Cell signaling directing the formation and function of hemogenic endothelium during murine embryogenesis.	GATA2 GATA1	8.45e-05	12	40	2	18684862
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	RTF1 GATA2 XRN1 EAF1 PTPRA BRF1 UBTF SACM1L	1.14e-04	1327	40	8	32694731
Pubmed	TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture.	NXF2 NXF5	1.16e-04	14	40	2	11073998
Pubmed	Transcriptional ontogeny of the developing liver.	A2M GATA1	1.34e-04	15	40	2	22260730
Pubmed	Gata6 is an important regulator of mouse pancreas development.	GATA2 GATA1	1.53e-04	16	40	2	16887115
Pubmed	Developmental competence of the gut endoderm: genetic potentiation by GATA and HNF3/fork head proteins.	GATA2 GATA1	1.53e-04	16	40	2	10208738
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	CEP192 ABCB10 MYRF CDC42EP3 UBTF SACM1L	1.61e-04	719	40	6	35337019
Pubmed	Mutations in linker-2 of KLF1 impair expression of membrane transporters and cytoskeletal proteins causing hemolysis.	GATA2 GATA1	1.73e-04	17	40	2	39147774
Pubmed	The Hemogenic Competence of Endothelial Progenitors Is Restricted by Runx1 Silencing during Embryonic Development.	GATA2 GATA1	1.73e-04	17	40	2	27239041
Pubmed	Beta-Actin Is Involved in Modulating Erythropoiesis during Development by Fine-Tuning Gata2 Expression Levels.	GATA2 GATA1	1.73e-04	17	40	2	23840778
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	WWC2 CEP192 CTNNAL1 PTPRA MTUS1 UBTF SDAD1	1.74e-04	1049	40	7	27880917
Pubmed	Geminin deletion increases the number of fetal hematopoietic stem cells by affecting the expression of key transcription factors.	GATA2 GATA1	1.95e-04	18	40	2	25516969
Pubmed	Prethymic T-cell development defined by the expression of paired immunoglobulin-like receptors.	GATA2 GATA1	2.18e-04	19	40	2	16292344
Pubmed	Endothelial Smad4 restrains the transition to hematopoietic progenitors via suppression of ERK activation.	GATA2 GATA1	2.42e-04	20	40	2	24553180
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	RTF1 DIAPH2 AK9 UBTF SDAD1	2.54e-04	497	40	5	36774506
Pubmed	Jak2 is essential for signaling through a variety of cytokine receptors.	GATA2 GATA1	2.67e-04	21	40	2	9590173
Pubmed	Rapid cDNA sequencing (expressed sequence tags) from a directionally cloned human infant brain cDNA library.	MTUS1 CAPN6	2.67e-04	21	40	2	8401585
Pubmed	Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac.	GATA2 GATA1	2.94e-04	22	40	2	9324354
Pubmed	AML1(-/-) embryos do not express certain hematopoiesis-related gene transcripts including those of the PU.1 gene.	GATA2 GATA1	2.94e-04	22	40	2	9811459
Pubmed	Regulation of Hematopoiesis and Methionine Homeostasis by mTORC1 Inhibitor NPRL2.	GATA2 GATA1	2.94e-04	22	40	2	26166573
Pubmed	Human midbrain dopaminergic neuronal differentiation markers predict cell therapy outcomes in a Parkinson's disease model.	GATA2 SIM2	3.21e-04	23	40	2	35700056
Pubmed	Global gene expression analysis of murine limb development.	SIM2 LHX9 PRDM1	3.35e-04	117	40	3	22174793
Cytoband	1q42.13	ABCB10 PGBD5	8.48e-04	49	40	2	1q42.13
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	GATA2 GATA1	1.91e-04	15	25	2	82
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	ANPEP CDCP1 ICAM1	1.66e-02	394	25	3	471
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	RIMBP2 CEP192	2.57e-02	181	25	2	694
ToppCell	10x5'v1-week_17-19-Myeloid_macrophage-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	A2M ANPEP MTUS1 ICAM1 PRDM1	9.34e-07	199	40	5	cbd423c31d75f6d2f5ae85d2241641fcbe630b81
ToppCell	10x5'v1-week_17-19-Myeloid_macrophage\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	A2M ANPEP MTUS1 ICAM1 PRDM1	9.34e-07	199	40	5	980b10b81ee9dc952e3be25bd294201ce5a4ca8b
ToppCell	5'-Adult-LargeIntestine-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GATA2 A2M CTNNAL1 MTUS1 CDC42EP3	9.34e-07	199	40	5	ffebd99d55d31cf51b4878b2690ed0b9b3799223
ToppCell	5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GATA2 A2M CTNNAL1 MTUS1 CDC42EP3	9.34e-07	199	40	5	258d59cf811bf1668ffbb5f18f961021f660de62
ToppCell	5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GATA2 A2M CTNNAL1 MTUS1 CDC42EP3	9.57e-07	200	40	5	cd3c638961144a2fc91c437a173cc37c7452fa74
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Calb1-Excitatory_Neuron.Sc17a7.Calb1-Lpl-Cadm2_(Layer_2/3,_Cadm2+)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	AK9 MYBPHL SIM2	1.10e-05	48	40	3	bbfc33299ea8e6895dd4d21a7dd38bec33563127
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CTNNAL1 CDCP1 PGBD5 ICAM1	1.94e-05	178	40	4	a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	RIMBP2 SIM2 CDCP1 CAPN6	1.98e-05	179	40	4	06f92c884189197c86793191c05f65e34925c097
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	WWC2 MYBPHL MTUS1 ICAM1	1.98e-05	179	40	4	cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCell	5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GATA2 A2M MTUS1 CDC42EP3	2.11e-05	182	40	4	0639011cdd1c437ea8b7230896a4e6e5d7244ac2
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYRFL MTUS1 SYTL5 PRDM1	2.21e-05	184	40	4	2ba98708dfd7f1b2a661578a334684094ff453ad
ToppCell	5'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GATA2 A2M MTUS1 ICAM1	2.21e-05	184	40	4	97e97de52daaff8840f4ee76a94ba5e3f79de7ce
ToppCell	COPD-Myeloid-Mast\|COPD / Disease state, Lineage and Cell class	GATA2 A2M CDC42EP3 GATA1	2.30e-05	186	40	4	def6f0f284acc2154738574c8c5d3d2a5ef1f208
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	WWC2 MYRF PGBD5 ICAM1	2.35e-05	187	40	4	d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GATA2 A2M CTNNAL1 ICAM1	2.35e-05	187	40	4	d6765854154557794815514c0aa355bc74b8523e
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYRFL MTUS1 SYTL5 PRDM1	2.50e-05	190	40	4	305fbef734c350cfbf786ca7ff6e07093aab56ea
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYRFL CDC42EP3 SYTL5 PRDM1	2.50e-05	190	40	4	0acf1d5da68db449d8c9e70519a236ce825f9d11
ToppCell	COPD-Myeloid-Mast\|Myeloid / Disease state, Lineage and Cell class	GATA2 A2M CDC42EP3 GATA1	2.50e-05	190	40	4	379dbac19110b76079a7a53209569e060a852acb
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MTUS1 CDC42EP3 SYTL5 PRDM1	2.50e-05	190	40	4	e58e4b6fbeb4368f738adac67ec10879c0966f0f
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GATA2 A2M MTUS1 CDC42EP3	2.55e-05	191	40	4	adb2e3efcad02889d8229325080da5e7830fd3ae
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GATA2 A2M MTUS1 ICAM1	2.66e-05	193	40	4	807fa1443b3c883cb318c71f4fca3c41d58f4910
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CTNNAL1 MTUS1 CDC42EP3 ICAM1	2.66e-05	193	40	4	c0973a2c97deb7176c2f617c8760a55f7edc9839
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GATA2 A2M MTUS1 ICAM1	2.66e-05	193	40	4	0f2967afbbf4e538b63f985c0acc2e5d9aab7589
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA2 MTUS1 ICAM1 PRDM1	2.77e-05	195	40	4	cad21edd90bf3e2fefdf5773a59cb1a664a69ddd
ToppCell	10x3'2.3-week_14-16-Myeloid_macrophage-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	A2M ANPEP ICAM1 PRDM1	2.82e-05	196	40	4	bd2c2de103e28b65ea537c22f71225cb0deef1e0
ToppCell	10x3'2.3-week_14-16-Myeloid_macrophage\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	A2M ANPEP ICAM1 PRDM1	2.82e-05	196	40	4	072a4150ae521c6589b0f7cd60e975fb33715bf4
ToppCell	5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GATA2 A2M MTUS1 CDC42EP3	2.88e-05	197	40	4	61b1b10a017cbeb17f8529fcae66cba77ee2f115
ToppCell	5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GATA2 A2M CTNNAL1 CDC42EP3	2.88e-05	197	40	4	87eda06344498dc66cac292cf89746dc90b5cf67
ToppCell	(4)_Endothelial_cells\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	GATA2 A2M CDC42EP3 ICAM1	2.88e-05	197	40	4	dd9abb43c23e7698433e455eacbf5b23b0a756c2
ToppCell	PBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	EAF1 ANPEP CDC42EP3 ICAM1	2.88e-05	197	40	4	383d598ce3f8f5fc98bef3300e4cf7b6992aec9c
ToppCell	distal-Endothelial-Bronchial_Vessel_1-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	A2M CTNNAL1 MTUS1 CDC42EP3	2.88e-05	197	40	4	0d1afd1ad7489c071db08b3dfff598423097d7e0
ToppCell	10x5'v1-week_12-13-Myeloid_macrophage-stroma-stromal_macrophage\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	A2M MTUS1 PGBD5 PRDM1	2.88e-05	197	40	4	075044c17f1c52008cd3c292c15cbf485b50411e
ToppCell	PBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	EAF1 ANPEP CDC42EP3 ICAM1	2.88e-05	197	40	4	3cc4e56a77f96a43f9b5a24cf1b9524c927ef795
ToppCell	(4)_Blood_vessel\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	GATA2 A2M CDC42EP3 ICAM1	2.88e-05	197	40	4	1b82979a41ef46c814c82527a585900586d71260
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GATA2 A2M MTUS1 CDC42EP3	2.88e-05	197	40	4	e8e879b7634a29569061d3515d180784094a31e7
ToppCell	distal-1-Endothelial-Bronchial_Vessel_1\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	A2M CTNNAL1 MTUS1 CDC42EP3	2.94e-05	198	40	4	5cd81fe1a21c0e1a7f0d5a62ddf8e422b05aedc7
ToppCell	5'-Adult-Appendix-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GATA2 A2M MTUS1 ICAM1	2.94e-05	198	40	4	90e85fe7a0ab376a41666dfff6c0e95b7f1c9475
ToppCell	5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GATA2 A2M MTUS1 CDC42EP3	2.94e-05	198	40	4	58508a8df2714d769f137794c29441a7bd38b350
ToppCell	5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GATA2 A2M MTUS1 CDC42EP3	2.94e-05	198	40	4	8a55589b9244283e4b0b423a4a6d6202e8e0fec9
ToppCell	severe-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	DIAPH2 ANPEP CDC42EP3 ICAM1	2.94e-05	198	40	4	d5e525d2f2226d06a3fb985ce3a33555ff4b2e7b
ToppCell	Endothelial_cells-Endothelial-A\|Endothelial_cells / lung cells shred on cell class, cell subclass, sample id	A2M CTNNAL1 CDC42EP3 ICAM1	3.00e-05	199	40	4	2a1424c61ddcd1fea9574f7a3ad1955387458130
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GATA2 A2M CTNNAL1 ICAM1	3.00e-05	199	40	4	ddfb725ccbcadbd188e20b60a7567e1f8245f18d
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GATA2 A2M CTNNAL1 MTUS1	3.00e-05	199	40	4	a8f2eb00c3e4267a174bc9eff307dc2e5d18c76e
ToppCell	Transplant_Alveoli_and_parenchyma-Endothelial-Endothelial\|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X	A2M CTNNAL1 CDC42EP3 ICAM1	3.05e-05	200	40	4	2ae62c428728c1d9d4471d4be24bd6ab074fa22c
ToppCell	3'-Adult-LargeIntestine-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GATA2 A2M CDC42EP3 ICAM1	3.05e-05	200	40	4	74a3b9ec8faa1d187ad8b0d12f5c89bde2d7248e
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Mast_cell\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	GATA2 CDC42EP3 PGBD5 GATA1	3.05e-05	200	40	4	c3511607692e05f44538a376253673dd18f77908
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / Treatment groups by lineage, cell group, cell type	WWC2 MTUS1 MYRF SYTL5	3.05e-05	200	40	4	2dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCell	Biopsy_IPF-Epithelial-KRT5-/KRT17+\|Biopsy_IPF / Sample group, Lineage and Cell type	MYRF PGBD5 ICAM1 CAPN6	3.05e-05	200	40	4	2fc7a3b3aea711ad3d96fd9513f4b40533056d86
ToppCell	5'-Adult-SmallIntestine-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GATA2 A2M MTUS1 CDC42EP3	3.05e-05	200	40	4	2554b77edfe3d378296b0b25625caacbfb1c0e76
ToppCell	3'-Adult-LargeIntestine-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GATA2 A2M CDC42EP3 ICAM1	3.05e-05	200	40	4	074b5766c61fa8e61d0b1b76688ea0d1ec401e5b
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Mast_cell-Mast_cell\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	GATA2 CDC42EP3 PGBD5 GATA1	3.05e-05	200	40	4	1c58860932ed47263a5a537a64f0343201463c21
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	EAF1 PGBD5 GATA1	1.92e-04	125	40	3	43aa4b77dccf0ea2979218826af16034f2017c3a
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	GATA2 MTUS1 ICAM1	2.20e-04	131	40	3	d5bc40cd585582856881081b7130dec3515b4ae0
ToppCell	LPS-IL1RA+antiTNF-Hematopoietic_Mast-Mast_cells-Mast-cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GATA2 PGBD5 GATA1	2.30e-04	133	40	3	81189e8516a431d5890a0909f9fc7c82ec3442bc
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Intermediate_Fibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	A2M MYBPHL PGBD5	2.51e-04	137	40	3	dd5364a1002650d21e0c83d8c701b5f7b09d1c19
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Fibroblasts\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SYTL5 CAPN6 PRDM1	2.85e-04	143	40	3	57ee1830d96d73d92b5f83b028592a5d952c6013
ToppCell	356C-Myeloid-Mast_cell\|356C / Donor, Lineage, Cell class and subclass (all cells)	GATA2 PGBD5 GATA1	3.15e-04	148	40	3	1668d8a9e680da335362744f36b05446c499347e
ToppCell	356C-Myeloid-Mast_cell-\|356C / Donor, Lineage, Cell class and subclass (all cells)	GATA2 PGBD5 GATA1	3.15e-04	148	40	3	18511ba10765eda937c5a710626361f7e6b9b321
ToppCell	368C-Myeloid-Mast_cell\|368C / Donor, Lineage, Cell class and subclass (all cells)	GATA2 PGBD5 GATA1	3.41e-04	152	40	3	faf30245a1690aaa27c7be0832797c340e4af4d7
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_granulocytic\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	GATA2 PGBD5 GATA1	3.41e-04	152	40	3	32634195048858ae84605c61e43c542d90f7cab5
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_granulocytic-mast_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	GATA2 PGBD5 GATA1	3.41e-04	152	40	3	0eb185b2404f015efff1bd140e0c502d714720fb
ToppCell	368C-Myeloid-Mast_cell-\|368C / Donor, Lineage, Cell class and subclass (all cells)	GATA2 PGBD5 GATA1	3.41e-04	152	40	3	519c9ed05fdaf420e42147ffae1dc05a7f86fdd4
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	A2M MYRF PRDM1	3.54e-04	154	40	3	e94cd11488003347120eacd3ced0a8923ed09ccc
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_granulocytic-mast_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	GATA2 PGBD5 GATA1	3.89e-04	159	40	3	ecd1daa33549541aee3bf4e139ab6732efc8e74c
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_granulocytic\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	GATA2 PGBD5 GATA1	3.89e-04	159	40	3	7b6370c9567da7d40541c6e243efa704ed7e90ae
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	WWC2 MTUS1 ICAM1	3.89e-04	159	40	3	8680b054622f573a82b1625fb93c2d5db81d1034
ToppCell	PND07-Epithelial-Epithelial_Airway-Neurosecretory-Secretory\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AK9 MTUS1 SYTL5	3.96e-04	160	40	3	028b5261a1da832d52f66fb620db83e5fbbd874a
ToppCell	PND07-Immune-Immune_Myeloid-Granulocytic-Mast\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GATA2 ABCB10 ANPEP	3.96e-04	160	40	3	ca212634cf1875238071d1800ecdf34979a553fb
ToppCell	PND07-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AK9 MTUS1 SYTL5	3.96e-04	160	40	3	1f4ee446436726c3d373f56d87dd80b6a12e8b9e
ToppCell	PND07-Immune-Immune_Myeloid-Granulocytic-Mast-Mast_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GATA2 ABCB10 ANPEP	3.96e-04	160	40	3	5d22c86deead516444349d495998e04586be4396
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RIMBP2 SIM2 PGBD5	4.03e-04	161	40	3	4bb7bae54ba3bdf46b525c01f5ad3db8e49819cb
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage\|356C / Donor, Lineage, Cell class and subclass (all cells)	EAF1 PGBD5 GATA1	4.11e-04	162	40	3	2f19539c455d1e5d514725845234c7547020e6ad
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GATA2 A2M CTNNAL1	4.18e-04	163	40	3	977a970b1296234c22178420294cea73506ee02f
ToppCell	URO-Lymphocyte-T_NK-MAIT\|URO / Disease, Lineage and Cell Type	MTUS1 MYRF PRDM1	4.25e-04	164	40	3	cb42a70433b3968caca67f7aa98ea536cd90a0bc
ToppCell	356C-Myeloid-Mast_cell\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	GATA2 PGBD5 GATA1	4.25e-04	164	40	3	b3192c443f4848e6a8afdb89c155f9ec42a154b0
ToppCell	356C-Myeloid-Mast_cell-\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	GATA2 PGBD5 GATA1	4.25e-04	164	40	3	f7288ec4daf494dae770ea6c58bead27660ccae1
ToppCell	LAM-Myeloid-Mast\|LAM / Condition, Lineage and Cell class	GATA2 PGBD5 GATA1	4.41e-04	166	40	3	e0ce973cc2a091b832c67b3b32dc153379daa2ef
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CEP192 MTUS1 SYTL5	4.49e-04	167	40	3	a90f905ef38437752e2b0b71bd0322a184de1861
ToppCell	NS-critical-d_07-13-Myeloid-Mast_cell\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	GATA2 PGBD5 GATA1	4.49e-04	167	40	3	8a14fd980d8ebe8ef0216221f619d31aaa27ff15
ToppCell	PBMC-Control-Hematopoietic-Platelet-Platelet-plt_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GATA2 CTNNAL1 GATA1	4.56e-04	168	40	3	2f69e248c6fab1421c0081e01e1920e6ffcde344
ToppCell	PBMC-Control-Hematopoietic-Platelet-Platelet-plt_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GATA2 CTNNAL1 GATA1	4.56e-04	168	40	3	2d056cfbb470a088a0682576753535fb4528d48f
ToppCell	COVID-19-lung-MAST\|lung / Disease (COVID-19 only), tissue and cell type	GATA2 PGBD5 GATA1	4.72e-04	170	40	3	e90f18e5462381b38e918442b38b1c8105291908
ToppCell	Control-Myeloid-Mast\|Control / Disease state, Lineage and Cell class	GATA2 A2M GATA1	4.72e-04	170	40	3	9a14deb7f7cd4a49c217eba4023f7bf1dec6c902
ToppCell	343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	GATA2 MYBPHL GATA1	4.81e-04	171	40	3	4ccd88cf812dd8bfdc55159c6f504e9c84e4f4fc
ToppCell	Control-Myeloid-Mast\|World / Disease state, Lineage and Cell class	GATA2 A2M GATA1	4.81e-04	171	40	3	ed8e61d524f4cddc6084b261175df54d2a64a60f
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	USP6 CDCP1 CAPN6	4.81e-04	171	40	3	b7cddb8f726a43fb8a37f3e67a3f722e2178fd7a
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	A2M USP6 PRDM1	4.89e-04	172	40	3	2b0333c21b7472194a7b9feb3de121da3340fc5b
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-I_cells_(CCK+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RIMBP2 ABCB10 CDCP1	4.89e-04	172	40	3	2651dece87c3e3d2d6370f5274ebae357474b825
ToppCell	368C-Myeloid-Mast_cell\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	GATA2 PGBD5 GATA1	4.97e-04	173	40	3	8cffb4a37d30b6626188309b868ac4a62e91262f
ToppCell	AT1_cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	WWC2 MYRF PGBD5	4.97e-04	173	40	3	3afca2a429c634af0220c1aa19ce4cf4ee3e8b3e
ToppCell	5'-Adult-Appendix-Hematopoietic-Myeloid-Mast_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GATA2 SIM2 GATA1	4.97e-04	173	40	3	a7dee23b1d43d3070d502487af319ff81a9a747b
ToppCell	368C-Myeloid-Mast_cell-\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	GATA2 PGBD5 GATA1	4.97e-04	173	40	3	fb87ea74bf70aa83b458edf728c81857c8b8eb96
ToppCell	10x5'-GI_small-bowel-Mast\|GI_small-bowel / Manually curated celltypes from each tissue	GATA2 PGBD5 GATA1	5.06e-04	174	40	3	e94c980b25edfd0e8598c416828801fcc00e8ead
ToppCell	facs-Heart-RA-24m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA2 A2M ICAM1	5.06e-04	174	40	3	42dfb6f42b72e40e203b3ef341117bccf3553d54
ToppCell	10x5'-GI_small-bowel-Mast-Mast_cells\|GI_small-bowel / Manually curated celltypes from each tissue	GATA2 PGBD5 GATA1	5.06e-04	174	40	3	05525bf0a2bde2be4f7c147b17a24530ce8819e0
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors\|lymph-node_spleen / Manually curated celltypes from each tissue	GATA2 UBTFL1 GATA1	5.06e-04	174	40	3	6d9bdf4d28ff8ebb66ffd1ccdd6a4fe9440a83f3
ToppCell	facs-Heart-RA-24m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA2 A2M ICAM1	5.06e-04	174	40	3	f04edf2ca6788875c9918611e416fb739924382e
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_3\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CDCP1 SYTL5 PGBD5	5.06e-04	174	40	3	9e5fae9ecc7c0111fc8a252e72b89dc89c0d3a7c
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NXF2 SIM2 CAPN6	5.14e-04	175	40	3	8b498eea1ec1c1f27b171025c3d08adf3687bafc
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NXF2 SIM2 CAPN6	5.14e-04	175	40	3	a5db428b078938627e61b7e944c1e0c1d61ac2da
Disease	diffuse large B-cell lymphoma (is_marker_for)	ICAM1 PRDM1	4.74e-05	8	39	2	DOID:0050745 (is_marker_for)
Disease	phosphatidylcholine 38:6 measurement	PTPRA MYRF	2.02e-04	16	39	2	EFO_0010388
Disease	depressive disorder (is_implicated_in)	GATA2 GATA1	2.29e-04	17	39	2	DOID:1596 (is_implicated_in)
Disease	phosphatidylcholine 40:6 measurement	PTPRA MYRF	2.29e-04	17	39	2	EFO_0010389
Disease	myelodysplastic syndrome (is_marker_for)	GATA2 GATA1	3.19e-04	20	39	2	DOID:0050908 (is_marker_for)
Disease	Hematopoetic Myelodysplasia	GATA2 GATA1	6.76e-04	29	39	2	C2713368
Disease	Alzheimer's disease (is_implicated_in)	XRN1 A2M ICAM1	7.11e-04	132	39	3	DOID:10652 (is_implicated_in)
Disease	clear cell renal cell carcinoma (is_marker_for)	GATA2 GATA1	8.76e-04	33	39	2	DOID:4467 (is_marker_for)
Disease	cholesteryl ester 16:0 measurement	MYRF DYNC2H1	1.04e-03	36	39	2	EFO_0010341
Disease	lung cancer (is_marker_for)	GATA1 PRDM1	1.22e-03	39	39	2	DOID:1324 (is_marker_for)
Disease	attention deficit hyperactivity disorder, conduct disorder	MYRFL PGBD5	1.29e-03	40	39	2	EFO_0003888, EFO_0004216
Disease	systolic blood pressure change measurement	OGDH MYRF	1.77e-03	47	39	2	EFO_0006944
Disease	acute myeloid leukemia (is_marker_for)	GATA2 GATA1	1.92e-03	49	39	2	DOID:9119 (is_marker_for)
Disease	mouth morphology measurement	CDC42EP3 SACM1L	2.00e-03	50	39	2	EFO_0007955

Protein segments in the cluster

Peptide	Gene	Start	Entry
INTEMPRQPKKFQKG	CDCP1	711	Q9H5V8
KKPKRGIQYLQEQGM	ARFGEF1	711	Q9Y6D6
KPNGIYRKLMNKQSF	ABCB10	721	Q9NRK6
GPMKNYLKKQVTPLF	ANPEP	716	P15144
PGISLNLPYGMKQKK	DIAPH2	616	O60879
MPAKTPIYLKAANNK	CDC42EP3	1	Q9UKI2
PMTVFKGNKRPYQKD	EAF1	71	Q96JC9
SKIRKPKMCPQLQQY	A2M	681	P01023
SYPRPNFKNVKAKVM	MTUS1	501	Q9ULD2
RDQQPYPPSQKTKRM	LHX9	256	Q9NQ69
PYSVKNKLKPGQMEM	NXF5	91	Q9H1B4
NNMRKKGKPNPDQRY	MYRFL	351	Q96LU7
TPPARGQYQIKMKGN	PGBD5	386	Q8N414
FTQPLMYKQIRKQKP	OGDH	521	Q02218
YHKMNGQNRPLIRPK	GATA1	231	P15976
LYHKMNGQNRPLIKP	GATA2	321	P23769
KVVKQYTMNPKAMPR	DYNC2H1	2001	Q8NCM8
YLSLPKPMKNNANLK	CTNNAL1	536	Q9UBT7
KYKKNYLPMQGNPPR	CENPJ	1091	Q9HC77
KNKMDIQGNPKYRAL	MYBPHL	296	A2RUH7
YINMPVQFKPKSAGK	CEP192	2496	Q8TEP8
KYRLQQAQKGTPMKP	ICAM1	511	P05362
MGPPLKLFKNQKYQE	CAPN6	1	Q9Y6Q1
KYKPLPQISKVANHM	SACM1L	271	Q9NTJ5
PANMKKNRVLQIIPY	PTPRA	556	P18433
APYSVKNKLKPGQME	NXF2	201	Q9GZY0
RFRKAPPNYAMKKTQ	RTF1	501	Q92541
MLPPEQLQGNKTFKK	SYTL5	561	Q8TDW5
EKFMKNPIKYIRQPK	AK9	1391	Q5TCS8
PNMAYKVKVLAKPHQ	RIMBP2	446	O15034
QQRPGRSPQYIMKVK	IGLV4-3	56	A0A075B6K6
KMKTKLRTNPYPPQQ	SIM2	376	Q14190
KNKRNMTGYKTLPYP	PRDM1	551	O75626
TLNPQMLQKKFRGKP	SDAD1	441	Q9NVU7
YNLLPSKQMPCKKNE	WWC2	821	Q6AWC2
KMNKSQKYRNGPDFP	UBTFL1	86	P0CB47
LPSQPKQNKKLASYM	XRN1	1396	Q8IZH2
PPSYTAGQRKLRMKQ	BRF1	291	Q92994
EPKKPPMNGYQKFSQ	UBTF	566	P17480
LKNPGRYQIMKERGK	USP6	121	P35125
KKGKPNPDQRYFMLV	MYRF	491	Q9Y2G1