Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentsymbiont cell surface

C4A C4B

1.37e-048472GO:0106139
GeneOntologyCellularComponentother organism part

C4A C4B

1.76e-049472GO:0044217
MousePhenoepididymis epithelium degeneration

BMP8B BMP8A

2.04e-053372MP:0004934
MousePhenokeratoconjunctivitis sicca

NRTN CHD7

4.08e-054372MP:0013466
MousePhenokeratoconjunctivitis

NRTN CHD7

6.78e-055372MP:0006194
MousePhenoepididymis degeneration

BMP8B BMP8A

1.42e-047372MP:0004935
DomainAnaphylatoxin_comp_syst

C4A C4B

5.40e-055442IPR018081
DomainAnaphylatoxn_comp_syst_dom

C4A C4B

5.40e-055442IPR001840
DomainTGFB

BMP8B NRTN BMP8A

8.96e-0537443SM00204
DomainTGF-b_C

BMP8B NRTN BMP8A

8.96e-0537443IPR001839
DomainTGF_BETA_2

BMP8B NRTN BMP8A

8.96e-0537443PS51362
DomainTGF_beta

BMP8B NRTN BMP8A

8.96e-0537443PF00019
DomainTGF_BETA_1

BMP8B NRTN BMP8A

8.96e-0537443PS00250
DomainANATO

C4A C4B

1.13e-047442SM00104
DomainANATO

C4A C4B

1.13e-047442PF01821
DomainANAPHYLATOXIN_2

C4A C4B

1.13e-047442PS01178
DomainANAPHYLATOXIN_1

C4A C4B

1.13e-047442PS01177
DomainAnaphylatoxin/fibulin

C4A C4B

1.13e-047442IPR000020
DomainThiol-ester_cl

C4A C4B

1.51e-048442PF10569
DomainMacrogloblnA2_thiol-ester-bond

C4A C4B

1.51e-048442IPR019565
DomainMacrogloblnA2_CS

C4A C4B

1.51e-048442IPR019742
DomainA2M_N

C4A C4B

2.41e-0410442PF01835
DomainA2M_N

C4A C4B

2.41e-0410442IPR002890
DomainA-macroglobulin_rcpt-bd

C4A C4B

2.41e-0410442IPR009048
DomainALPHA_2_MACROGLOBULIN

C4A C4B

2.41e-0410442PS00477
DomainA2M

C4A C4B

2.41e-0410442PF00207
DomainA2M_N_2

C4A C4B

2.41e-0410442IPR011625
DomainA2M_comp

C4A C4B

2.41e-0410442IPR011626
DomainA2M_N_2

C4A C4B

2.41e-0410442PF07703
DomainA2M_recep

C4A C4B

2.41e-0410442PF07677
DomainA2M_comp

C4A C4B

2.41e-0410442PF07678
DomainMacroglobln_a2

C4A C4B

2.41e-0410442IPR001599
DomainSpy1

SPDYE1 SPDYE21

2.94e-0411442PF11357
DomainSpeedy

SPDYE1 SPDYE21

2.94e-0411442IPR020984
DomainInhibin_asu

BMP8B BMP8A

4.16e-0413442IPR002405
Domain-

BMP8B NRTN BMP8A

5.26e-04674432.10.90.10
DomainCystine-knot_cytokine

BMP8B NRTN BMP8A

5.26e-0467443IPR029034
DomainC345C

C4A C4B

7.21e-0417442SM00643
DomainTerpenoid_cyclase/PrenylTrfase

C4A C4B

8.10e-0418442IPR008930
DomainNTR

C4A C4B

9.04e-0419442PF01759
DomainNetrin_module_non-TIMP

C4A C4B

9.04e-0419442IPR018933
DomainNTR

C4A C4B

1.33e-0323442PS50189
DomainNetrin_domain

C4A C4B

1.33e-0323442IPR001134
DomainTIMP-like_OB-fold

C4A C4B

1.70e-0326442IPR008993
DomainTGFb_propeptide

BMP8B BMP8A

1.97e-0328442PF00688
DomainTGF-b_N

BMP8B BMP8A

1.97e-0328442IPR001111
DomainTGF-beta-rel

BMP8B BMP8A

2.57e-0332442IPR015615
DomainTGFb_CS

BMP8B BMP8A

2.57e-0332442IPR017948
DomaincNMP

RAPGEF6 PRKG2

2.90e-0334442SM00100
DomaincNMP_binding

RAPGEF6 PRKG2

2.90e-0334442PF00027
DomaincNMP-bd_dom

RAPGEF6 PRKG2

3.07e-0335442IPR000595
DomainCNMP_BINDING_3

RAPGEF6 PRKG2

3.07e-0335442PS50042
DomaincNMP-bd-like

RAPGEF6 PRKG2

3.61e-0338442IPR018490
DomainPDZ

RAPGEF6 GRID2IP RGS12

4.45e-03141443PF00595
DomainPDZ

RAPGEF6 GRID2IP RGS12

5.09e-03148443SM00228
Domain-

RAPGEF6 GRID2IP RGS12

5.28e-031504432.30.42.10
DomainPDZ

RAPGEF6 GRID2IP RGS12

5.38e-03151443PS50106
DomainPDZ

RAPGEF6 GRID2IP RGS12

5.48e-03152443IPR001478
Domain-

RAPGEF6 PRKG2

5.71e-03484422.60.120.10
DomainSANT

MTA2 CHD7

6.18e-0350442SM00717
DomainRmlC-like_jellyroll

RAPGEF6 PRKG2

6.43e-0351442IPR014710
PathwayREACTOME_ACTIVATION_OF_C3_AND_C5

C4A C4B

1.18e-047342MM14685
PathwayREACTOME_ACTIVATION_OF_C3_AND_C5

C4A C4B

1.57e-048342M27031
PathwayKEGG_MEDICUS_REFERENCE_CLASSICAL_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION

C4A C4B

1.57e-048342M47872
PathwayBIOCARTA_LECTIN_PATHWAY

C4A C4B

3.06e-0411342MM1430
PathwayKEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION

C4A C4B

3.06e-0411342M47874
PathwayBIOCARTA_CLASSIC_PATHWAY

C4A C4B

3.67e-0412342MM1368
PathwayBIOCARTA_LECTIN_PATHWAY

C4A C4B

4.33e-0413342M4732
PathwayBIOCARTA_CLASSIC_PATHWAY

C4A C4B

5.81e-0415342M7146
PathwayKEGG_MEDICUS_REFERENCE_BMP_SIGNALING_PATHWAY_BMP_ANTAGONIST

BMP8B BMP8A

5.81e-0415342M47824
PathwayWP_COMPLEMENT_ACTIVATION_CLASSICAL_PATHWAY

C4A C4B

7.51e-0417342MM15944
PathwayBIOCARTA_COMP_PATHWAY

C4A C4B

7.51e-0417342MM1369
PathwayWP_EGFR1_SIGNALING_PATHWAY

MTA2 PIK3CG SH3KBP1 SIN3A

1.04e-03188344MM15828
PathwayKEGG_MEDICUS_REFERENCE_BMP_SIGNALING_PATHWAY

BMP8B BMP8A

1.04e-0320342M47843
PathwayBIOCARTA_COMP_PATHWAY

C4A C4B

1.04e-0320342M917
PathwayWP_COMPLEMENT_ACTIVATION

C4A C4B

1.27e-0322342M39502
Pubmed

PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.

MTA2 HYOU1 UBE4B SPTBN2 C4A C4B NKTR HNRNPL

3.83e-0747750831300519
Pubmed

Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.

C4A C4B

2.03e-06250222737222
Pubmed

Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.

C4A C4B

2.03e-06250216565498
Pubmed

Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.

C4A C4B

2.03e-06250215998580
Pubmed

C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.

C4A C4B

2.03e-06250225339671
Pubmed

A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.

C4A C4B

2.03e-06250217728371
Pubmed

Structural polymorphism of murine C4 and its linkage to H-2.

C4A C4B

2.03e-0625027373044
Pubmed

High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.

C4A C4B

2.03e-06250219062096
Pubmed

The chemical structure of the C4d fragment of the human complement component C4.

C4A C4B

2.03e-0625023696167
Pubmed

Structure and organization of the C4 genes.

C4A C4B

2.03e-0625026149580
Pubmed

Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.

C4A C4B

2.03e-0625026149581
Pubmed

Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.

C4A C4B

2.03e-0625021357031
Pubmed

Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.

C4A C4B

2.03e-06250216098595
Pubmed

Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.

C4A C4B

2.03e-06250219933335
Pubmed

The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.

C4A C4B

2.03e-06250212115608
Pubmed

Biochemistry and biology of anaphylatoxins.

C4A C4B

2.03e-0625023542363
Pubmed

Human BMP8A suppresses luteinization of rat granulosa cells via the SMAD1/5/8 pathway.

BMP8B BMP8A

2.03e-06250231940275
Pubmed

C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.

C4A C4B

2.03e-0625022387317
Pubmed

Promoter elements of the mouse complement C4 gene critical for transcription activation and start site location.

C4A C4B

2.03e-0625028132550
Pubmed

Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.

C4A C4B

2.03e-0625022459207
Pubmed

Antigen-induced B cell apoptosis is independent of complement C4.

C4A C4B

2.03e-06250217645767
Pubmed

Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.

C4A C4B

2.03e-06250215787745
Pubmed

Anti-DNA autoreactivity in C4-deficient mice.

C4A C4B

2.03e-06250212207352
Pubmed

Substitution of a single amino acid (aspartic acid for histidine) converts the functional activity of human complement C4B to C4A.

C4A C4B

2.03e-0625022395880
Pubmed

Effects of Complement C4 Gene Copy Number Variations, Size Dichotomy, and C4A Deficiency on Genetic Risk and Clinical Presentation of Systemic Lupus Erythematosus in East Asian Populations.

C4A C4B

2.03e-06250226814708
Pubmed

cDNA clone spanning the alpha-gamma subunit junction in the precursor of the murine fourth complement component (C4).

C4A C4B

2.03e-0625026192448
Pubmed

Complete primary structure of human C4a anaphylatoxin.

C4A C4B

2.03e-0625026167582
Pubmed

Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.

C4A C4B

2.03e-06250216908004
Pubmed

Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.

C4A C4B

2.03e-06250230026462
Pubmed

Slp is an essential component of an EDTA-resistant activation pathway of mouse complement.

C4A C4B

2.03e-0625021438267
Pubmed

Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.

C4A C4B

2.03e-0625027365238
Pubmed

A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.

C4A C4B

2.03e-0625026559257
Pubmed

Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.

C4A C4B

2.03e-06250227758680
Pubmed

Genetic deficiency of complement isoforms C4A or C4B predicts improved survival of metastatic renal cell carcinoma.

C4A C4B

2.03e-06250219150565
Pubmed

Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.

C4A C4B

2.03e-0625027391573
Pubmed

Elevated levels of endogenous apoptotic DNA and IFN-alpha in complement C4-deficient mice: implications for induction of systemic lupus erythematosus.

C4A C4B

2.03e-06250217506029
Pubmed

Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.

C4A C4B

2.03e-06250222387014
Pubmed

Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.

C4A C4B

2.03e-06250217971360
Pubmed

Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Spectrum Disorder Subjects.

C4A C4B

2.03e-06250234299197
Pubmed

Assessment of complement C4 gene copy number using the paralog ratio test.

C4A C4B

2.03e-06250220506482
Pubmed

Low C4 gene copy numbers are associated with superior graft survival in patients transplanted with a deceased donor kidney.

C4A C4B

2.03e-06250223715124
Pubmed

Identification of the 5'-flanking regulatory region responsible for the difference in transcriptional control between mouse complement C4 and Slp genes.

C4A C4B

2.03e-0625023464002
Pubmed

Complete nucleotide and derived amino acid sequences of the fourth component of mouse complement (C4). Evolutionary aspects.

C4A C4B

2.03e-0625022993295
Pubmed

Clinical features of patients with homozygous complement C4A or C4B deficiency.

C4A C4B

2.03e-06250229928053
Pubmed

The protective role of bone morphogenetic protein-8 in the glucocorticoid-induced apoptosis on bone cells.

BMP8B BMP8A

2.03e-06250221277400
Pubmed

Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.

C4A C4B

2.03e-06250217971229
Pubmed

Polymerase chain reaction based C4AQ0 and C4BQ0 genotyping: association with systemic lupus erythematosus in southwest Han Chinese.

C4A C4B

2.03e-06250212480675
Pubmed

Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease. Genetic and immunologic studies.

C4A C4B

2.03e-0625026881182
Pubmed

Low C4, C4A and C4B gene copy numbers are stronger risk factors for juvenile-onset than for adult-onset systemic lupus erythematosus.

C4A C4B

2.03e-06250226800705
Pubmed

Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.

C4A C4B

2.03e-06250223749435
Pubmed

Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.

C4A C4B

2.03e-06250223918728
Pubmed

Identification of the site of sulfation of the fourth component of human complement.

C4A C4B

2.03e-0625023944109
Pubmed

Murine complement C4 is not required for experimental autoimmune encephalomyelitis.

C4A C4B

2.03e-06250215390104
Pubmed

Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.

C4A C4B

2.03e-0625023037333
Pubmed

Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.

C4A C4B

2.03e-06250211726230
Pubmed

Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.

C4A C4B

2.03e-0625024216347
Pubmed

Partial C4 deficiency in juvenile idiopathic arthritis patients.

C4A C4B

2.03e-06250217921792
Pubmed

Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant.

C4A C4B

2.03e-06250221880985
Pubmed

Importance of the alpha 3-fragment of complement C4 for the binding with C4b-binding protein.

C4A C4B

2.03e-0625021699796
Pubmed

Amino acid sequence around the thiol and reactive acyl groups of human complement component C4.

C4A C4B

2.03e-0625026978711
Pubmed

Sequence determination of the thiolester site of the fourth component of human complement.

C4A C4B

2.03e-0625026950384
Pubmed

Molecular cloning and characterization of complementary and genomic DNA clones for mouse C4 and Slp.

C4A C4B

2.03e-0625022997024
Pubmed

Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD.

C4A C4B

2.03e-06250235898513
Pubmed

Overexpression of schizophrenia susceptibility factor human complement C4A promotes excessive synaptic loss and behavioral changes in mice.

C4A C4B

2.03e-06250233353966
Pubmed

Sequence comparison of alleles of the fourth component of complement (C4) and sex-limited protein (Slp).

C4A C4B

2.03e-0625023008092
Pubmed

Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.

C4A C4B

2.03e-0625028660986
Pubmed

Constitutive expression of Slp genes in mouse strain B10.WR directed by C4 regulatory sequences.

C4A C4B

2.03e-0625023624865
Pubmed

Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival.

C4A C4B

2.03e-06250228873507
Pubmed

Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.

C4A C4B

2.03e-0625028428773
Pubmed

Determination of the loss of function complement C4 exon 29 CT insertion using a novel paralog-specific assay in healthy UK and Spanish populations.

C4A C4B

2.03e-06250221857912
Pubmed

Bone morphogenetic protein 8A plays a role in the maintenance of spermatogenesis and the integrity of the epididymis.

BMP8B BMP8A

2.03e-0625029463357
Pubmed

The gene encoding bone morphogenetic protein 8B is required for the initiation and maintenance of spermatogenesis in the mouse.

BMP8B BMP8A

2.03e-0625028682296
Pubmed

The molecular basis for the difference in immune hemolysis activity of the Chido and Rodgers isotypes of human complement component C4.

C4A C4B

2.03e-0625026609966
Pubmed

Heterogeneity and linkage of equine C4 and steroid 21-hydroxylase genes.

C4A C4B

2.03e-0625022900855
Pubmed

Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.

C4A C4B

2.03e-06250224638111
Pubmed

Isolation of cDNA clones specifying the fourth component of mouse complement and its isotype, sex-limited protein.

C4A C4B

2.03e-0625026208559
Pubmed

The role of the histocompatibility-2-linked Ss-Slp region in the control of mouse complement.

C4A C4B

2.03e-0625024514997
Pubmed

Studies on the murine Ss protein: demonstration that the Ss protein is functionally the fourth component of complement.

C4A C4B

2.03e-062502276882
Pubmed

Transcriptional repression of C4 complement by hepatitis C virus proteins.

C4A C4B

2.03e-06250221345967
Pubmed

The inheritance of susceptibility to the Gross leukemia virus in mice.

C4A C4B

2.03e-0625025919331
Pubmed

Amino acid sequence of a polymorphic segment from fragment C4d of human complement component C4.

C4A C4B

2.03e-0625026832377
Pubmed

An ancient provirus has imposed androgen regulation on the adjacent mouse sex-limited protein gene.

C4A C4B

2.03e-0625023167981
Pubmed

Recombination of two homologous MHC class III genes of the mouse (C4 and Slp) that accounts for the loss of testosterone dependence of sex-limited protein expression.

C4A C4B

2.03e-0625023794341
Pubmed

Complement and c4 null alleles in severe chronic adult periodontitis.

C4A C4B

2.03e-06250217257223
Pubmed

Three extra copies of a C4-related gene in H-2w7 mice are C4/Slp hybrid genes generated by multiple recombinational events.

C4A C4B

2.03e-0625022272665
Pubmed

Multiple C4/Slp genes distinguished by expression after transfection.

C4A C4B

2.03e-0625023023818
Pubmed

The dichotomous size variation of human complement C4 genes is mediated by a novel family of endogenous retroviruses, which also establishes species-specific genomic patterns among Old World primates.

C4A C4B

2.03e-0625027545960
Pubmed

Insights on the relationship between complement component C4 serum concentrations and C4 gene copy numbers in a Western Australian systemic lupus erythematosus cohort.

C4A C4B

2.03e-06250230041577
Pubmed

Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.

C4A C4B

2.03e-0625022572548
Pubmed

Fine-tuned characterization of RCCX copy number variants and their relationship with extended MHC haplotypes.

C4A C4B

2.03e-06250222785613
Pubmed

The complement component C4 of mammals.

C4A C4B

2.03e-0625022302180
Pubmed

Complete cDNA sequence of the fourth component of murine complement.

C4A C4B

2.03e-0625023862104
Pubmed

The BS variant of C4 protects against age-related loss of white matter microstructural integrity.

C4A C4B

2.03e-06250234358307
Pubmed

Association between complement 4 copy number variation and systemic lupus erythematosus: a meta-analysis.

C4A C4B

2.03e-06250232691186
Pubmed

Genetic deficiency in complement component 4b does not alter radiation-induced lung disease in mice.

C4A C4B

2.03e-06250223259761
Pubmed

Acute renal allograft rejection: diagnostic significance of focal peritubular capillary C4d.

C4A C4B

2.03e-06250218360261
Pubmed

Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.

C4A C4B

2.03e-06250222151770
Pubmed

C4d-positive chronic rejection: a frequent entity with a poor outcome.

C4A C4B

2.03e-06250218091514
Pubmed

Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.

C4A C4B

2.03e-06250229080553
Pubmed

Lack of evidence of a specific role for C4A gene deficiency in determining disease susceptibility among C4-deficient patients with systemic lupus erythematosus (SLE).

C4A C4B

2.03e-06250211168010
CytobandEnsembl 112 genes in cytogenetic band chr1p34

BMP8B PTPRF BMP8A

4.08e-03294503chr1p34
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

C4A C4B

1.23e-0493421234
GeneFamilyBone morphogenetic proteins|Astacins

BMP8B BMP8A

1.87e-0411342455
GeneFamilyEndogenous ligands

BMP8B NRTN BMP8A CTSG

9.80e-04237344542
GeneFamilyComplement system|Sushi domain containing

C4A C4B

2.08e-0336342492
GeneFamilyGlycosyltransferase family 6|Blood group antigens

C4A C4B

2.19e-0337342454
GeneFamilyCyclins|F-boxes other

CCNF FBXO3

2.44e-0339342560
GeneFamilyPDZ domain containing

RAPGEF6 GRID2IP RGS12

2.88e-031523431220
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

MTA2 CHD7

4.45e-0353342532
CoexpressionXIE_TRASTUZUMAB_CARDIOTOXICITY_MMU_MIR_345_5P_GENES

BMP8B HYOU1 DRAXIN BMP8A

1.54e-0580494MM17502
CoexpressionGSE27241_WT_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_UP

RAPGEF6 PIK3CG SH3KBP1 PHF14 CHD7

1.73e-05172495M8234
ToppCell10x5'-Lung-Lymphocytic_T_CD4-Tfh|Lung / Manually curated celltypes from each tissue

CYP27B1 C20orf204 ZDBF2 PRKG2

1.56e-05134504da3cb572d0c19932619e51e272c0555e91b482ac
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRABD2A DRAXIN SH3KBP1 TRAF3IP3

3.36e-05163504e6213900f56257fe38ac7852351bea0340294be0
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRABD2A DRAXIN SH3KBP1 TRAF3IP3

3.36e-05163504ed7319185c1ec384444309bb8be95691a0c2091c
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRABD2A DRAXIN SH3KBP1 TRAF3IP3

3.36e-05163504ef35d7ff09aa364734fea7fdaab6260c0a3fbf09
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCNF INCENP ATAD2 KIF17

4.14e-05172504c06ca5d075937747952ed915c9db39a9f62072f9
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAPGEF6 SH3KBP1 TRAF3IP3 RPL4

4.33e-0517450476694cd8a1162047a9ee60521ce84201b4378a47
ToppCelldroplet-Lung-21m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

INCENP SIN3A BMP8A ATAD2

4.43e-051755046751ee4b312d7f87275f2c35e5878cfc3be3ebe3
ToppCellClub-club-15|World / Class top

MTA2 INCENP SH3KBP1 ATAD2

4.43e-05175504ca9d012f520f697c7450ec6958a015e20538a6a8
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAPGEF6 SH3KBP1 TRAF3IP3 RPL4

4.43e-05175504f7547eade69aa1d012db963adf59f36a309beae6
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAPGEF6 SH3KBP1 TRAF3IP3 RPL4

4.53e-051765048960b3b9aca11f6edf990dd35a01bb289c176523
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAPGEF6 SH3KBP1 TRAF3IP3 RPL4

4.63e-0517750413f22e578728be477b097889af483b1e3f3e18bb
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAPGEF6 SH3KBP1 TRAF3IP3 RPL4

4.63e-0517750481511383b010ab744ebc622c180f926d469194c1
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAPGEF6 SH3KBP1 TRAF3IP3 RPL4

4.63e-051775040d6167c6a11c7dec0717ae7c8b4c45341585804f
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAPGEF6 SH3KBP1 TRAF3IP3 RPL4

4.63e-051775045b8fdf88c3a99c827dd1934beb5be102c411025a
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAPGEF6 SH3KBP1 TRAF3IP3 RPL4

4.63e-05177504c840efec4eba746543eac0f48dd688518f0fb5f0
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAPGEF6 SH3KBP1 TRAF3IP3 RPL4

4.73e-05178504a8d6aae3c35de6e7d1421cc48e58688adbdf16aa
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAPGEF6 SH3KBP1 TRAF3IP3 RPL4

4.84e-051795048498f94202434b3cb5d84f1a37d3ad191baf664e
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAPGEF6 SH3KBP1 TRAF3IP3 RPL4

4.84e-0517950420cac7b3035a2bb0b09f58741617550f1f623fc9
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAPGEF6 SH3KBP1 TRAF3IP3 RPL4

5.05e-0518150461c6e000db7047fda4b4bb5024f3af24577e7d29
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAPGEF6 SH3KBP1 TRAF3IP3 RPL4

5.05e-051815046a32eb83aa39484ca43c91e6b58302d8dea84b7e
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SPDYE1 DRAXIN PHF14 CHD7

5.27e-05183504af14da45267261e775dd6dab7a4c359b181e46f1
ToppCellBrain_organoid-organoid_Kanton_Nature|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.

PEG10 PHF14 NKTR CHD7

5.50e-05185504857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCellDividing_Macrophages-HP_01|World / lung cells shred on cell class, cell subclass, sample id

CCNF INCENP ATAD2 CTSG

6.22e-051915043e567ed6b5fefafa7f460e49d25d60bb52a0a6c8
ToppCellPBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_T_naive-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRABD2A C20orf204 TRAF3IP3 RPL4

6.48e-051935046436d3bfce02d137b76e5c4c8b2fe27974c57c99
ToppCellPBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_T_naive-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TRABD2A C20orf204 TRAF3IP3 RPL4

6.48e-051935043cde93bbfc1ae6fb586ae6b7aaa6ed8b5eee28a4
ToppCellPBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_T_naive|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TRABD2A C20orf204 TRAF3IP3 RPL4

6.48e-05193504d755dc6de4fbd4d8f5d8a88aac497e7b9e8b89de
ToppCellPBMC-Control-Lymphocyte-T/NK-CD8+_T-CD8+_T_naive|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRABD2A C20orf204 TRAF3IP3 RPL4

6.48e-05193504d371403b51281a6e37652fa8dc1b2dd81d2ab371
ToppCellsevere-B_cell|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BMP8B PEG10 ZDBF2 CHD7

6.61e-051945042fee6083fb56b16d1f04fd0b92ec622fd26ba3fa
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasmablast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BMP8B PIK3CG CYP27B1 BMP8A

6.74e-05195504c6e31038be2463f1601d52c82efa4e9facb8228f
ToppCellT_cells-CCR7+_T_cells|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

TRABD2A RAPGEF6 CHD7 RPL4

7.29e-05199504467820d6abe3024d9d655b9672c2f9cdc1303db3
ToppCellmedial-Hematologic-CD4+_Naive_T-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TRABD2A RAPGEF6 TRAF3IP3 RPL4

7.29e-051995046a896a447388fd525cff207e17a5371c0f6b38cb
ToppCellmedial-2-Hematologic-CD4+_Naive_T|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TRABD2A RAPGEF6 TRAF3IP3 RPL4

7.29e-05199504231a539899e2b76215da3e96a6755799f722e278
ToppCellmedial-Hematologic-CD4+_Naive_T|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TRABD2A RAPGEF6 TRAF3IP3 RPL4

7.29e-05199504a54c35a646ae23bdd35c278ffb027408cf8dd553
ToppCellControl-Control-Myeloid-immature_Neutrophil|Control / Disease, condition lineage and cell class

R3HCC1L INCENP CHD7 CTSG

7.44e-05200504118321ac443feb42aee171baccfc4610f00a8822
ToppCellSepsis-Int-URO-Lymphocyte-T/NK-T/NK_proliferative|Int-URO / Disease, condition lineage and cell class

CCNF INCENP CYP27B1 ATAD2

7.44e-0520050499acc1ea01288efdd5b166aa20d66735f2bbe543
ToppCellLymphoid-B_cells_(cycle)|World / shred on cell class and cell subclass (v4)

CCNF INCENP CTSG

2.63e-04111503df23af931ce0258ce97d6b4c7125ae1ab16a7eaa
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Vip_Itih5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRID2IP PIK3CG RGS12

3.00e-04116503605bd4fdf547cc41783e99cd78425760ef6461ef
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Vip_Nptx2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NRTN PEG10 RGS12

3.47e-0412250391e338db581b36baffecc323b1909f2069b27242
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Nr2f2_Necab1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NRTN PIK3CG PRKG2

3.64e-04124503298ff8bd8f0459f44ce8a8aea889c6f1cf84ac5f
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Pltp|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NRTN CHD7 RGS12

3.64e-0412450336dfc702a570e1a1a6dde09f38badf9023ea7287
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Car10|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NRTN PEG10 RGS12

3.91e-04127503f808c727c0817ed10e76eaffa9493a516e9a6b50
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sncg|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NRTN PIK3CG RGS12

4.47e-04133503840e8240db29cd21ed9830843c0fa6d65b8f300a
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Hematologic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C4A TRAF3IP3 TEP1

5.41e-0414250339ada235a46f2202c093cf2336de224a5957ed1a
ToppCellBac-SEP-Lymphocyte-T_NK-CD8_Naive|Bac-SEP / Disease, Lineage and Cell Type

TRABD2A NRTN PRKG2

5.64e-04144503fdcf84e8b5fdc0730f243919f9cc30492e24dd75
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NRTN PEG10 RGS12

5.64e-0414450304f9054895be2275eecda687a6eeb02fa5ec69b9
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NRTN PEG10 RGS12

6.10e-041485035e738522d4ad35e08bc4ff8c41b7bea38ec6ef95
ToppCellE16.5-samps-Myeloid-Fetal_macrophage-macrophage_-_intermediate_-_unactivated|E16.5-samps / Age Group, Lineage, Cell class and subclass

DRAXIN PIK3CG TRAF3IP3

6.35e-0415050360fdd266aaca1b589b9a77465a4a7fad4921339a
ToppCell3'_v3-Lung-Lymphocytic_T_CD4-Tnaive/CM_CD4_activated|Lung / Manually curated celltypes from each tissue

TRABD2A C20orf204 ZDBF2

6.47e-041515039bfb807e1180b31fa9a2c500ce993de9707c070f
ToppCellCOVID-CD4-proli_CD4|COVID / Condition, Cell_class and T cell subcluster

TRABD2A NRTN CYP27B1

6.47e-04151503dd40dfc5b1211d31607e16d9b433a5c1796e7edf
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C4A TRAF3IP3 TEP1

6.60e-04152503bfc7ef4ee26165d18ac4f475a9519e8d52453ba2
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NRTN PEG10 RGS12

6.98e-04155503105d59d8a1bb8cb37eef2c1767d737b2108ac7c5
ToppCell343B-Lymphocytic-NK_cells-NK_cell_B0|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CYP27B1 C20orf204 PRKG2

6.98e-04155503583cfaa41c755c63aee312eb442e9d97f645d5f7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCNF SPTBN2 ATAD2

6.98e-041555038b524c65fa5c901f70c7caae4ec7fd2859eaf227
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_low-phase|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCNF SPTBN2 ATAD2

6.98e-041555037fe8b8c0c8a9e3190cfd52d3934509e6780e1717
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

RAPGEF6 NKTR SMG6

7.11e-041565031545169694f686d28648a68b552c2ae606599d66
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-microglial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP8B CYP27B1 TRAF3IP3

7.24e-04157503c762b03e254c73222094725ca8ac1c8eb428bccb
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP8B CYP27B1 TRAF3IP3

7.24e-041575036b5b08bb5520fcf6f4c0560f7ed7645ec179806d
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP8B CYP27B1 TRAF3IP3

7.24e-041575037fdc0094dd5729990a91a30c1982a14c74650b52
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Pygm_C1ql1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NRTN PEG10 RGS12

7.79e-041615033b5d7a3dab479c6959a428f3954dedd989900276
ToppCellPCW_13-14-Neuronal-Neuronal_postreplicative-neuro_immature_neuronal_(2)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

BMP8B SPTBN2 C9orf163

7.79e-04161503bb9cb42882aaa4a1ecf9b480c0e7ac302f2c0d5d
ToppCellsevere_influenza-CD8+_T_naive|severe_influenza / disease group, cell group and cell class (v2)

TRABD2A ZDBF2 CHD7

7.79e-0416150382196139cdbbd70a36957a87bc9ac6d02575da3f
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

TRABD2A RAPGEF6 NKTR

7.93e-04162503b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

INCENP TEP1 KIF17

7.93e-04162503ec29c6f1c31e41ddcb041a49c593910edaf0532c
ToppCellASK428-Immune-Mast_cell|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

SH3KBP1 DIAPH2-AS1 CTSG

8.07e-04163503569ca0e8ce307f258910b0c75c498009a9651e6e
ToppCell356C-Lymphocytic-NK_cells-NK_cell_E|356C / Donor, Lineage, Cell class and subclass (all cells)

INCENP DRAXIN SMG6

8.22e-04164503d5bb57c321f2973836efc8990449494cc1fb87c7
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

INCENP TP53I13 ATAD2

8.22e-041645035621c2e3fae84d5a2e4f1595e454bcb3a2b3f93c
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3KBP1 TRAF3IP3 KIF17

8.22e-041645031a9b444d2c6abcc83d4355ec5228b27541df2bd0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCNF INCENP ATAD2

8.36e-04165503eec2d327c94832d1390314c93ef6a2be4648478b
ToppCellhealthy_donor-Lymphocytic-Plasma_cell-IgM_Plasmablast|healthy_donor / Disease condition, Lineage, Cell class and subclass

BMP8B HYOU1 CTSG

8.51e-041665032b7b580bec8d9467b0deaf97098065f72dbf2a4f
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell-mesothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPTBN2 ZDBF2 KIF17

8.66e-041675031adb566f98af0109c8cc6e36033b89651e2c75e7
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPTBN2 ZDBF2 KIF17

8.66e-04167503743df5908c1ceb43b34b240d9f9649f30f4142fa
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCNF INCENP SH3KBP1

8.66e-04167503d21635df8b74189e3309eaf435af381fbe412574
ToppCellPCW_07-8.5-Immune_Lymphocytic-Immune_Lymphocytic_B-im_B_cell_(15)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

BMP8B PIK3CG TRAF3IP3

8.81e-041685032ec53f91de3bff8a106430a78b81ee6870f0c55e
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCNF INCENP ATAD2

8.81e-04168503a1755afa2cc50960ba60e07d84d61be429cdea72
ToppCellASK428-Immune-Mast_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

BMP8B DIAPH2-AS1 CTSG

8.81e-04168503c399fcb4d1d0be48026c2ecabc34a5935e7adf73
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|343B / Donor, Lineage, Cell class and subclass (all cells)

PEG10 PRKG2 ATAD2

8.96e-04169503a949f547b53126a208819bade74a1ac9b2a36ea7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCNF INCENP ATAD2

8.96e-04169503b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCell343B-Lymphocytic-NK_cells-NK_cell_B0|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

CYP27B1 C20orf204 PRKG2

8.96e-0416950389b5452e0d8d058648a1d2659f1611fd6aebc6b6
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|343B / Donor, Lineage, Cell class and subclass (all cells)

PEG10 PRKG2 ATAD2

8.96e-04169503195d5cd60d646ac6d40a3321b2f739917e7aef14
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCNF INCENP ATAD2

9.12e-0417050321bfe070e63722672176052b386167ea4c3dc4e5
ToppCellASK454-Immune-NK_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

DRAXIN TRAF3IP3 PRKG2

9.12e-0417050384705434234bf2fbb5256bd5a1f6ab54c01c5a51
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCNF PIK3CG C4B

9.12e-041705037534ac69ca3a378df78d61c284e89bc96a71a4a8
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

CCNF INCENP ATAD2

9.12e-041705035319f73cff64f2bb67472c7156ee1d0f006c6fc0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CCNF PIK3CG ATAD2

9.27e-04171503c2dbc439af28d4fabb24d57685b75b2e588819b0
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SH3KBP1 TRAF3IP3 RPL4

9.27e-04171503801893c318f7b1abc8d97bac86a00974f910a71c
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAPGEF6 SH3KBP1 RPL4

9.43e-0417250325bf2551d698237bfd912c2ff067b1600dfb19ca
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCNF NOP16 TRAF3IP3

9.43e-0417250376c06a968d3333441eed103abef1e636a1c3e7a1
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SH3KBP1 TRAF3IP3 CTSG

9.43e-041725033a37569a5902f3c65ff8d3912421309a8c82ee9b
ToppCellASK454-Immune-NK_cell|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

DRAXIN TRAF3IP3 PRKG2

9.43e-04172503c9e738c3540ee09b08805b1cdb66b4a0d9d40d33
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Mast_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SH3KBP1 TRAF3IP3 CTSG

9.43e-04172503cc9d9dae290f11f8c348c78228af4e49469dc93b
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

INCENP ATAD2 KIF17

9.43e-041725037c238a7375341d4647ba7274d93fddfb6fae7ce4
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l5|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RAPGEF6 TRAF3IP3 RPL4

9.43e-041725035b1f6d4e09e6465acb80b58846ad387e38b155ab
ToppCelldroplet-Kidney-KIDNEY-1m-Lymphocytic-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRAF3IP3 BMP8A ATAD2

9.59e-04173503de124fb7ded04664d4184bf12f1f201c0784f07c
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAPGEF6 SH3KBP1 RPL4

9.59e-0417350346dbc51270cc80d6e0b7118c53cec8516b1bb508
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

INCENP TEP1 KIF17

9.59e-04173503506efcaa5afd6ed5e565c4c4def6a4505fea97c5
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors-Progenitor_Myeloid|bone_marrow / Manually curated celltypes from each tissue

INCENP MLNR CTSG

9.59e-041735035645a3b1e805c71d5d65fc8e4edc4e13208063fc
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-5_VIP_KCNJ2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PEG10 CHD7 RGS12

9.75e-04174503fdadac1eaab2c4a67e4832f0901df22e893add6a
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-5_VIP_KCNJ2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PEG10 CHD7 RGS12

9.75e-041745038d8cf8ad17dcc364f867e36b10834a21c0e36ad2
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-CD4+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPGEF6 SH3KBP1 TRAF3IP3

9.75e-04174503fedadde222df1952d6456f4f3413c01579146e1f
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPGEF6 SH3KBP1 TRAF3IP3

9.75e-04174503e69a011ae9698368923223d3af3243e609c08c83
Diseasesystemic lupus erythematosus (implicated_via_orthology)

MTA2 C4A C4B

4.47e-0543473DOID:9074 (implicated_via_orthology)
DiseaseImmunologic Deficiency Syndromes

C4A CHD7

6.15e-0423472C0021051
Diseasetotal blood protein measurement

HYOU1 SH3KBP1 C20orf204 RGS12 SMG6

7.23e-04449475EFO_0004536
Diseasediabetes mellitus (implicated_via_orthology)

BMP8B BMP8A

7.88e-0426472DOID:9351 (implicated_via_orthology)
DiseaseComplement deficiency disease

C4A C4B

1.27e-0333472C0272242
DiseaseGraves' disease (is_implicated_in)

C4A C4B

1.77e-0339472DOID:12361 (is_implicated_in)
Diseaseautistic disorder (is_implicated_in)

PIK3CG C4B

2.05e-0342472DOID:12849 (is_implicated_in)
Diseasefree androgen index

PTPRF UBE4B CHD7 SIN3A

2.95e-03374474EFO_0007005
Diseasesystemic lupus erythematosus (is_implicated_in)

C4A C4B

4.42e-0362472DOID:9074 (is_implicated_in)
Diseaserenal cell carcinoma (is_implicated_in)

C4A C4B

5.44e-0369472DOID:4450 (is_implicated_in)
DiseaseLupus Erythematosus, Systemic

C4A C4B

5.75e-0371472C0024141

Protein segments in the cluster

PeptideGeneStartEntry
NGCRRRRQDRTKERP

SMG6

276

Q86US8
VNQCDIRRRPTRFLR

DIAPH2-AS1

111

Q14236
GRRNRRRREAPKVVE

C4B

1446

P0C0L5
VISVPRQQGRRRCRE

C9orf163

71

Q8N9P6
RRHCRTLRQRSRRPK

C20orf204

136

A0A1B0GTL2
RKRSRNRAINRCLPL

ATAD2

376

Q6PL18
VPRQRRRRRRKIEIE

CHD7

2396

Q9P2D1
MQQESERCRVRARRP

R3HCC1L

1

Q7Z5L2
RRMCRDLLQPRRAAR

MTA2

466

O94776
RRLLQPSRRVKRSRR

TP53I13

361

Q8NBR0
RRRLRRERVRAQPCC

NRTN

151

Q99748
VVCDLVRRLRRQRGR

CYP27B1

161

O15528
DENRDPIRRRLSRRK

INCENP

76

Q9NQS7
RVFDVPIRRRRCSRL

FBXO3

456

Q9UK99
PQRREVAKRKIRRLR

PEG10

161

Q86TG7
RLNLCARRRTRVQRP

MTPAP

11

Q9NVV4
MRNRRRIQRRGPCII

RPL4

196

P36578
RVPRERRQRQSVLQK

PHF14

846

O94880
TRRPEDLIRRLCRQN

PRKG2

676

Q13237
HRNRRVTRRKGRCVE

DRAXIN

321

Q8NBI3
MADKVRRQRPRRRVC

HYOU1

1

Q9Y4L1
SRERLVRLARRCPRV

GRID2IP

61

A4D2P6
CYPTKRRIRRRPRNL

CCNF

16

P41002
CPQRRLGARERRDVQ

BMP8A

31

Q7Z5Y6
LPRAEKRRRRLEQRQ

HNRNPL

6

P14866
PRRQICVGDRRERKA

CTSG

181

P08311
CPQRRLGARERRDVQ

BMP8B

31

P34820
GRRNRRRREAPKVVE

C4A

1446

P0C0L4
CRPLRARVLVTRRRV

MLNR

141

O43193
EEQRRRRRQAERLKP

PTPRF

1171

P10586
RCRPMNQRERELRCQ

KIF17

11

Q9P2E2
PKNRRTIEVNRCRRR

MRPL32

81

Q9BYC8
REIPARQSRRRFRKI

RAPGEF6

131

Q8TEU7
VRKTARLNRRPRNQE

NKTR

1281

P30414
RLPERSRQRLRLREC

NBEAL2

1191

Q6ZNJ1
RTNKRGERRRRRCQV

SH3KBP1

91

Q96B97
LPRNLRRIRKCQRGR

SIN3A

1126

Q96ST3
LRESTLRRRRVCPQA

HERC2P3

831

Q9BVR0
RLNRNARRKAAPRIE

NOP16

21

Q9Y3C1
VLREDNCRRRRRMKP

PIK3CG

11

P48736
RQEIRESRRCRPNVT

TRAF3IP3

26

Q9Y228
PSVQSCRRLRERRVA

RGS12

696

O14924
RILTRNEKNRPRRRF

TEP1

596

Q99973
PMRERCRRLQASREQ

SPTBN2

1476

O15020
PLRQRLEERQRRRKQ

SPEF1

106

Q9Y4P9
KRRFQLRRCMNPRAR

SPDYE21

336

A0A494C086
LRRCMNPRARKNRSQ

SPDYE21

341

A0A494C086
PSCRRYIRRLRAIRE

UBE4B

771

O95155
PLVRKRRFQLRRCMN

SPDYE1

266

Q8NFV5
RRFQLRRCMNPRARK

SPDYE1

271

Q8NFV5
RRCMNPRARKNRSQI

SPDYE1

276

Q8NFV5
PKRPVRASCRVARRR

ZDBF2

2291

Q9HCK1
EQRFRKKRRRSQRRP

TRABD2A

416

Q86V40