Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH10 DYNC2H1 DNAH2 DNAH17 DNAH5

6.57e-08181235GO:0008569
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH10 DYNC2H1 DNAH2 DNAH17 DNAH5

7.17e-07281235GO:0051959
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH10 DYNC2H1 DNAH2 DNAH17 DNAH5

3.04e-06371235GO:0045505
GeneOntologyMolecularFunctioncell adhesion molecule binding

DSCAM RPS2 ICAM4 ADGRL1 SIRPB1 ACTN2 GRIN2B NECTIN3 CEMIP2 SIRPG PTPRB KIRREL1 SEPTIN7 HCFC1

1.96e-0559912314GO:0050839
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH10 DYNC2H1 DNAH2 DNAH17 DNAH5

7.18e-05701235GO:0003777
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNAH10 MYO7A DYNC2H1 DNAH2 DNAH17 DNAH5

9.07e-051181236GO:0003774
GeneOntologyMolecularFunctionadenylate cyclase activity

ADCY5 ADCY6 ADCY7

1.74e-04181233GO:0004016
GeneOntologyMolecularFunctionscaffold protein binding

GRIN2B CIT ADCY5 ADCY6 KCNQ1

2.76e-04931235GO:0097110
GeneOntologyMolecularFunctioncalcium- and calmodulin-responsive adenylate cyclase activity

ADCY5 ADCY6

3.72e-0451232GO:0008294
GeneOntologyMolecularFunctioncyclase activity

ADCY5 ADCY6 ADCY7

4.20e-04241233GO:0009975
GeneOntologyMolecularFunctionphosphorus-oxygen lyase activity

ADCY5 ADCY6 ADCY7

4.75e-04251233GO:0016849
GeneOntologyMolecularFunctionsolute:inorganic anion antiporter activity

SLC25A14 SLC25A30 SLC4A9

9.93e-04321233GO:0005452
GeneOntologyMolecularFunctionantigen binding

IGHV3-48 IGKV1-17 IGHV3-11 SIRPB1 SIRPG IGHV3-64

1.16e-031901236GO:0003823
GeneOntologyMolecularFunctionmonoatomic cation channel activity

KCNH7 PIEZO1 PKD1L1 GRIN2B PKD1L2 KCNH6 KCNQ1 KCNQ2

1.30e-033431238GO:0005261
GeneOntologyCellularComponentaxonemal dynein complex

DNAH10 DNAH2 DNAH17 DNAH5

1.35e-05251244GO:0005858
GeneOntologyCellularComponentdynein complex

DNAH10 DYNC2H1 DNAH2 DNAH17 DNAH5

1.70e-05541245GO:0030286
GeneOntologyCellularComponentaxoneme

DNAH10 DYNC2H1 DNAH2 ARFGEF2 PIERCE1 DNAH17 SEPTIN7 DNAH5

3.33e-052071248GO:0005930
GeneOntologyCellularComponentciliary plasm

DNAH10 DYNC2H1 DNAH2 ARFGEF2 PIERCE1 DNAH17 SEPTIN7 DNAH5

3.44e-052081248GO:0097014
GeneOntologyCellularComponentcilium

DNAH10 MYO7A DYNC2H1 USP9X PKD1L1 DNAH2 ARFGEF2 ADCY5 ADCY6 USH1G PIERCE1 DNAH17 KCNQ1 SEPTIN7 DNAH5

2.82e-0489812415GO:0005929
GeneOntologyCellularComponentmicrotubule associated complex

FNTA DNAH10 DYNC2H1 DNAH2 DNAH17 DNAH5

4.02e-041611246GO:0005875
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

DNAH10 DYNC2H1 DNAH2 ARFGEF2 PIERCE1 DNAH17 SEPTIN7 DNAH5

6.15e-043171248GO:0032838
GeneOntologyCellularComponentaxon

RELN DSCAM PACSIN1 USP9X ADGRL1 GRIN2B NECTIN3 GDPD5 LRP1 KCNQ2 PYGB ALCAM SEPTIN7 HCFC1

8.28e-0489112414GO:0030424
DomainDHC_N1

DNAH10 DYNC2H1 DNAH2 DNAH5

1.04e-0781184PF08385
DomainDynein_heavy_dom-1

DNAH10 DYNC2H1 DNAH2 DNAH5

1.04e-0781184IPR013594
DomainDynein_heavy_chain_D4_dom

DNAH10 DYNC2H1 DNAH2 DNAH5

1.44e-06141184IPR024317
DomainDynein_HC_stalk

DNAH10 DYNC2H1 DNAH2 DNAH5

1.44e-06141184IPR024743
DomainDynein_heavy_dom-2

DNAH10 DYNC2H1 DNAH2 DNAH5

1.44e-06141184IPR013602
DomainDHC_N2

DNAH10 DYNC2H1 DNAH2 DNAH5

1.44e-06141184PF08393
DomainATPase_dyneun-rel_AAA

DNAH10 DYNC2H1 DNAH2 DNAH5

1.44e-06141184IPR011704
DomainMT

DNAH10 DYNC2H1 DNAH2 DNAH5

1.44e-06141184PF12777
DomainAAA_8

DNAH10 DYNC2H1 DNAH2 DNAH5

1.44e-06141184PF12780
DomainAAA_5

DNAH10 DYNC2H1 DNAH2 DNAH5

1.44e-06141184PF07728
DomainDHC_fam

DNAH10 DYNC2H1 DNAH2 DNAH5

1.96e-06151184IPR026983
DomainDynein_heavy

DNAH10 DYNC2H1 DNAH2 DNAH5

1.96e-06151184PF03028
DomainDynein_heavy_dom

DNAH10 DYNC2H1 DNAH2 DNAH5

1.96e-06151184IPR004273
DomainAdcy_conserved_dom

ADCY5 ADCY6 ADCY7

4.85e-0661183IPR009398
DomainDUF1053

ADCY5 ADCY6 ADCY7

4.85e-0661183PF06327
DomainAC_N

ADCY5 ADCY6 ADCY7

1.35e-0581183IPR032628
DomainAdcy

ADCY5 ADCY6 ADCY7

1.35e-0581183IPR030672
DomainAC_N

ADCY5 ADCY6 ADCY7

1.35e-0581183PF16214
DomainQuinoprot_gluc/sorb_DH

EML5 HHIPL2 LRP1

5.19e-05121183IPR011041
DomainMit_uncoupling

SLC25A14 SLC25A30 SLC25A32

5.19e-05121183IPR002030
DomainK_chnl_volt-dep_ERG

KCNH7 KCNH6

1.18e-0431182IPR003967
DomainA/G_cyclase_CS

ADCY5 ADCY6 ADCY7

1.57e-04171183IPR018297
Domain-

ADCY5 ADCY6 ADCY7

1.87e-041811833.30.70.1230
DomainNucleotide_cyclase

ADCY5 ADCY6 ADCY7

1.87e-04181183IPR029787
DomainGuanylate_cyc

ADCY5 ADCY6 ADCY7

2.21e-04191183PF00211
DomainGUANYLATE_CYCLASE_2

ADCY5 ADCY6 ADCY7

2.21e-04191183PS50125
DomainA/G_cyclase

ADCY5 ADCY6 ADCY7

2.21e-04191183IPR001054
DomainGUANYLATE_CYCLASE_1

ADCY5 ADCY6 ADCY7

2.21e-04191183PS00452
DomainCYCc

ADCY5 ADCY6 ADCY7

2.21e-04191183SM00044
DomainREJ

PKD1L1 PKD1L2

2.36e-0441182PS51111
DomainREJ_dom

PKD1L1 PKD1L2

2.36e-0441182IPR014010
DomainIg_V-set

DSCAM SIRPB1 NECTIN3 SIRPG KIRREL1 ALCAM TREML2

2.73e-041991187IPR013106
Domain-

SLC25A21 SLC25A14 SLC25A30 SLC25A32

3.49e-045311841.50.40.10
DomainMito_carr

SLC25A21 SLC25A14 SLC25A30 SLC25A32

3.49e-04531184PF00153
DomainSOLCAR

SLC25A21 SLC25A14 SLC25A30 SLC25A32

3.49e-04531184PS50920
DomainMitochondrial_sb/sol_carrier

SLC25A21 SLC25A14 SLC25A30 SLC25A32

3.49e-04531184IPR018108
DomainMt_carrier_dom

SLC25A21 SLC25A14 SLC25A30 SLC25A32

3.49e-04531184IPR023395
DomainK_chnl_volt-dep_KCNQ_C

KCNQ1 KCNQ2

3.91e-0451182IPR013821
DomainGal_Lectin

ADGRL1 PKD1L2

3.91e-0451182PF02140
DomainK_chnl_volt-dep_KCNQ

KCNQ1 KCNQ2

3.91e-0451182IPR003937
DomainLectin_gal-bd_dom

ADGRL1 PKD1L2

3.91e-0451182IPR000922
DomainSUEL_LECTIN

ADGRL1 PKD1L2

3.91e-0451182PS50228
DomainKCNQ_channel

KCNQ1 KCNQ2

3.91e-0451182PF03520
DomainHELP

EML6 EML5

5.84e-0461182PF03451
DomainPKD/REJ-like

PKD1L1 PKD1L2

5.84e-0461182IPR002859
DomainREJ

PKD1L1 PKD1L2

5.84e-0461182PF02010
DomainHELP

EML6 EML5

5.84e-0461182IPR005108
DomainMit_carrier

SLC25A21 SLC25A14 SLC25A32

1.07e-03321183IPR002067
DomainV-set

SIRPB1 NECTIN3 SIRPG KIRREL1 ALCAM TREML2

1.12e-031841186PF07686
DomainIGv

DSCAM SIRPB1 SIRPG ALCAM

1.30e-03751184SM00406
DomainGPS

PKD1L1 ADGRL1 PKD1L2

1.51e-03361183PS50221
DomainGPS

PKD1L1 ADGRL1 PKD1L2

1.63e-03371183IPR000203
DomainPAS_9

KCNH7 KCNH6

1.72e-03101182PF13426
DomainPKD_channel

PKD1L1 PKD1L2

2.10e-03111182PF08016
DomainPKD1_2_channel

PKD1L1 PKD1L2

2.10e-03111182IPR013122
DomainC2-set_2

NECTIN3 KIRREL1 ALCAM

2.20e-03411183PF08205
DomainCD80_C2-set

NECTIN3 KIRREL1 ALCAM

2.20e-03411183IPR013162
DomainKelch_2

HCFC2 HCFC1

2.95e-03131182IPR011498
DomainKelch_2

HCFC2 HCFC1

2.95e-03131182PF07646
Domain6-blade_b-propeller_TolB-like

WSB1 HHIPL2 LRP1

3.06e-03461183IPR011042
Domain-

DSCAM ICAM4 SIRPB1 NECTIN3 SIRPG PTPRB KIRREL1 ALCAM HCFC2 HCFC1 TREML2

3.19e-03663118112.60.40.10
DomainPLAC

THSD4 PCSK5

3.43e-03141182PF08686
DomainK_chnl_volt-dep_EAG/ELK/ERG

KCNH7 KCNH6

3.43e-03141182IPR003938
DomainQuinoprotein_ADH-like_supfam

EML6 AASDH EML5

4.58e-03531183IPR011047
DomainIg-like_fold

DSCAM ICAM4 SIRPB1 NECTIN3 SIRPG PTPRB KIRREL1 ALCAM HCFC2 HCFC1 TREML2

5.11e-0370611811IPR013783
DomainLH2

PKD1L1 PKD1L2

5.67e-03181182SM00308
DomainFurin_repeat

PCSK5 FRAS1

5.67e-03181182IPR006212
DomainFU

PCSK5 FRAS1

5.67e-03181182SM00261
DomainIon_trans_dom

KCNH7 KCNH6 KCNQ1 KCNQ2

5.93e-031141184IPR005821
DomainIon_trans

KCNH7 KCNH6 KCNQ1 KCNQ2

5.93e-031141184PF00520
DomainPLAC

THSD4 PCSK5

6.31e-03191182PS50900
DomainPLAC

THSD4 PCSK5

6.31e-03191182IPR010909
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH10 DNAH2 DNAH17 DNAH5

4.15e-05271034M47755
PathwayREACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY

ADCY5 ADCY6 ADCY7

4.38e-05101033M19522
PathwayREACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY

ADCY5 ADCY6 ADCY7

4.38e-05101033MM14668
PathwayREACTOME_FCGR3A_MEDIATED_IL10_SYNTHESIS

IGHV3-48 IGKV1-17 IGHV3-11 ADCY5 ADCY6 ADCY7

6.75e-05951036M29842
PathwayREACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY

ADCY5 ADCY6 ADCY7

1.30e-04141033MM14669
PathwayREACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY

ADCY5 ADCY6 ADCY7

1.30e-04141033M750
PathwayKEGG_MEDICUS_REFERENCE_EP_NE_ADRB_CAMP_SIGNALING_PATHWAY

ADCY5 ADCY6 ADCY7

1.62e-04151033M47794
PathwayPID_LPA4_PATHWAY

ADCY5 ADCY6 ADCY7

1.62e-04151033M56
PathwayKEGG_MEDICUS_REFERENCE_PTH_PTH1R_PKA_SIGNALING_PATHWAY

ADCY5 ADCY6 ADCY7

1.62e-04151033M47504
PathwayKEGG_MEDICUS_REFERENCE_LHCGR_GNAS_PKA_SIGNALING_PATHWAY

ADCY5 ADCY6 ADCY7

1.98e-04161033M47645
PathwayKEGG_MEDICUS_REFERENCE_FSHR_GNAS_PKA_SIGNALING_PATHWAY

ADCY5 ADCY6 ADCY7

1.98e-04161033M47650
PathwayREACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB

ADCY5 ADCY6 ADCY7

1.98e-04161033MM14492
PathwayWP_MAJOR_RECEPTORS_TARGETED_BY_EPINEPHRINE_AND_NOREPINEPHRINE

ADCY5 ADCY6 ADCY7

1.98e-04161033M39849
PathwayREACTOME_PKA_ACTIVATION_IN_GLUCAGON_SIGNALLING

ADCY5 ADCY6 ADCY7

2.39e-04171033M26995
PathwayKEGG_MEDICUS_REFERENCE_CX3CR1_GNAI_AC_PKA_SIGNALING_PATHWAY

ADCY5 ADCY6 ADCY7

2.39e-04171033M47544
PathwayKEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT

DNAH10 DNAH2 DNAH17 DNAH5

2.66e-04431034M47669
PathwayREACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS

KCNH7 KCNH6 KCNQ1 KCNQ2

2.66e-04431034M1056
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH10 DNAH2 DNAH17 DNAH5

3.18e-04451034M47670
PathwayREACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB

ADCY5 ADCY6 ADCY7

3.95e-04201033M759
PathwayREACTOME_ANTI_INFLAMMATORY_RESPONSE_FAVOURING_LEISHMANIA_PARASITE_INFECTION

IGHV3-48 IGKV1-17 IGHV3-11 ADCY5 ADCY6 ADCY7

4.43e-041341036M29840
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY

ADCY5 ADCY6 ADCY7

6.86e-04241033M47520
PathwayWP_PHOSPHODIESTERASES_IN_NEURONAL_FUNCTION

GRIN2B ADCY5 ADCY6 ADCY7

6.89e-04551034M39763
PathwayKEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAI_AC_PKA_SIGNALING_PATHWAY

ADCY5 ADCY6 ADCY7

8.72e-04261033M47553
PathwayREACTOME_CA_DEPENDENT_EVENTS

ADCY5 ADCY6 ADCY7

8.72e-04261033MM14495
PathwayREACTOME_CELL_CELL_COMMUNICATION

SIRPB1 ACTN2 NECTIN3 SIRPG AGO1 KIRREL1

9.54e-041551036M522
PathwayREACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS

IGHV3-48 IGHV3-11 LRP1 IGHV3-64

9.58e-04601034MM14872
PathwayKEGG_MEDICUS_REFERENCE_CRHR_PKA_ACTH_SIGNALING_PATHWAY

ADCY5 ADCY6 ADCY7

9.75e-04271033M47518
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_RASD1_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY

ADCY5 ADCY6 ADCY7

9.75e-04271033M47519
PathwayKEGG_MEDICUS_REFERENCE_GHRHR_PKA_GH_SIGNALING_PATHWAY

ADCY5 ADCY6 ADCY7

1.09e-03281033M47647
PathwayKEGG_MEDICUS_REFERENCE_TSH_TG_SIGNALING_PATHWAY

ADCY5 ADCY6 ADCY7

1.21e-03291033M47627
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_ACTH_CORTISOL_SIGNALING_PATHWAY

ADCY5 ADCY6 ADCY7

1.21e-03291033M47515
PathwayKEGG_MEDICUS_VARIANT_CYP11B1_CYP11B2_FUSION_TO_ACTH_CORTISOL_SIGNALING_PATHWAY

ADCY5 ADCY6 ADCY7

1.47e-03311033M47507
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH10 DYNC2H1 DNAH2 DNAH17 DNAH5

1.04e-091412459373155
Pubmed

Comprehensive analysis of the expression patterns of the adenylate cyclase gene family in the developing and adult mouse brain.

RELN ADCY5 ADCY6 ADCY7

3.18e-0810124416615126
Pubmed

Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning.

MYO7A ADCY5 ADCY6 ADCY7

2.71e-0716124417567809
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH2 DNAH17 DNAH5

1.53e-067124331178125
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

PCSK5 FRAS1 DYNC2H1 PKD1L1 LRP1 DNAH5

1.65e-06100124625807483
Pubmed

Characterization of the human adenylyl cyclase gene family: cDNA, gene structure, and tissue distribution of the nine isoforms.

ADCY5 ADCY6 ADCY7

3.66e-069124312503609
Pubmed

Role of the calcium modulated cyclases in the development of the retinal projections.

ADCY5 ADCY6 ADCY7

3.66e-069124317229090
Pubmed

Mechanism of human immunodeficiency virus-induced complement expression in astrocytes and neurons.

ADCY5 ADCY6 ADCY7

5.21e-0610124311884542
Pubmed

Purification and characterization of a soluble form of mammalian adenylyl cyclase.

ADCY5 ADCY6 ADCY7

5.21e-061012438663304
Pubmed

Bimodal regulation of an Elk subfamily K+ channel by phosphatidylinositol 4,5-bisphosphate.

KCNH7 KCNH6 KCNQ1

5.21e-0610124326503718
Pubmed

Vti1b promotes TRPV1 sensitization during inflammatory pain.

MYO7A RPS2 YBX3 ACTN2 PLEKHA6 FDPS

6.61e-06127124630335684
Pubmed

Involvement of adenylate cyclase and p70(S6)-kinase activation in IL-10 up-regulation in human monocytes by gp41 envelope protein of human immunodeficiency virus type 1.

ADCY5 ADCY6 ADCY7

7.15e-0611124310089566
Pubmed

gp120- and TNF-alpha-induced modulation of human B cell function: proliferation, cyclic AMP generation, Ig production, and B-cell receptor expression.

ADCY5 ADCY6 ADCY7

7.15e-0611124310808179
Pubmed

IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes.

IGHV3-48 IGKV1-17 IGKV1-6 IGHV3-11 IGHV3-64

8.55e-0677124515608191
Pubmed

HIV-1 envelope protein gp41 modulates expression of interleukin-10 and chemokine receptors on monocytes, astrocytes and neurones.

ADCY5 ADCY6 ADCY7

9.51e-0612124310807185
Pubmed

Expression of adenylyl cyclase mRNAs in the denervated and in the developing mouse skeletal muscle.

ADCY5 ADCY6 ADCY7

9.51e-061212439611134
Pubmed

Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.

RELN PACSIN1 SLC25A14 LAMA1 FRS3 DGKA PYGB

1.10e-05210124716537572
Pubmed

Polycystin-1L2 is a novel G-protein-binding protein.

PKD1L1 PKD1L2

1.26e-052124215203210
Pubmed

Knockout of adenylyl cyclase isoform 5 or 6 differentially modifies the β1-adrenoceptor-mediated inotropic response.

ADCY5 ADCY6

1.26e-052124231009605
Pubmed

Association of lipocalin-2 and low-density lipoprotein receptor-related protein-1 (LRP1) with biomarkers of environmental enteric dysfunction (EED) among under 2 children in Bangladesh: results from a community-based intervention study.

LCN2 LRP1

1.26e-052124234423140
Pubmed

The eag family of K+ channels in Drosophila and mammals.

KCNH7 KCNH6

1.26e-052124210414305
Pubmed

The calcium paradoxon of renin release: calcium suppresses renin exocytosis by inhibition of calcium-dependent adenylate cyclases AC5 and AC6.

ADCY5 ADCY6

1.26e-052124217068292
Pubmed

Adenylyl cyclase 5-generated cAMP controls cerebral vascular reactivity during diabetic hyperglycemia.

ADCY5 ADCY6

1.26e-052124231162142
Pubmed

The human uncoupling proteins 5 and 6 (UCP5/SLC25A14 and UCP6/SLC25A30) transport sulfur oxyanions, phosphate and dicarboxylates.

SLC25A14 SLC25A30

1.26e-052124231356773
Pubmed

Structure of MyTH4-FERM domains in myosin VIIa tail bound to cargo.

MYO7A USH1G

1.26e-052124221311020
Pubmed

Differential regulation of vascular tone and remodeling via stimulation of type 2 and type 6 adenylyl cyclases in the ductus arteriosus.

ADCY5 ADCY6

1.26e-052124220431059
Pubmed

Amino acid sequence of the Fv region of a human monoclonal IgM (protein WEA) with antibody activity against 3,4-pyruvylated galactose in Klebsiella polysaccharides K30 and K33.

IGHV3-48 IGKV1-17

1.26e-05212426410398
Pubmed

LRP1 is critical for the surface distribution and internalization of the NR2B NMDA receptor subtype.

GRIN2B LRP1

1.26e-052124223866919
Pubmed

Type VI adenylyl cyclase negatively regulates GluN2B-mediated LTD and spatial reversal learning.

GRIN2B ADCY6

1.26e-052124226932446
Pubmed

Adenylyl cyclase subtype-specific compartmentalization: differential regulation of L-type Ca2+ current in ventricular myocytes.

ADCY5 ADCY6

1.26e-052124223609114
Pubmed

Adenylyl cyclase type 5 protein expression during cardiac development and stress.

ADCY5 ADCY6

1.26e-052124219734365
Pubmed

Stimulation of renin secretion by catecholamines is dependent on adenylyl cyclases 5 and 6.

ADCY5 ADCY6

1.26e-052124221282557
Pubmed

Cloning and sequence of partial cDNAs encoding the human type V and VI adenylyl cyclases and subsequent RNA-quantification in various tissues.

ADCY5 ADCY6

1.26e-052124210481931
Pubmed

International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels.

KCNH7 KCNH6 KCNQ1 KCNQ2

1.27e-0540124416382104
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

MYO7A PACSIN1 RPS2 USP9X ARFGEF2 ADGRL1 ACTN2 GRIN2B PLEKHA6 CIT AGO1 KCNQ2 PYGB USP4 SEPTIN7 CNOT1 SCAI

1.36e-0514311241737142655
Pubmed

A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse.

KCNH7 MYO7A PLEKHA6 CIT KCNQ2

1.39e-0585124523055939
Pubmed

Isoforms of mammalian adenylyl cyclase: multiplicities of signaling.

ADCY5 ADCY6 ADCY7

1.56e-0514124314993377
Pubmed

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.

KCNH7 ABL2 ADGRL1 SIRPB1 NECTIN3 CEMIP2 SIRPG KCNQ2 SEPTIN7

1.57e-05405124938187761
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

ACOT8 MYO7A DYNC2H1 USP9X DNAH2 SAR1A PPP4R4 USH1G FECH MIB1 CNOT1

1.89e-056381241131182584
Pubmed

1.3 A X-ray structure of an antibody Fv fragment used for induced membrane-protein crystallization.

IGHV3-48 IGHV3-11 IGHV3-64

1.95e-0515124312657787
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

PCSK5 FRAS1 ERF DGKA ADCY6 CEMIP2 SLC25A32 GTPBP2 SUPT5H PYGB HCFC1

2.24e-056501241138777146
Pubmed

Human variation in alcohol response is influenced by variation in neuronal signaling genes.

DOCK2 IDO1 MYO7A ACTN2 GRIN2B PTPRB

3.58e-05171124620201926
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

ABL2 ADGRL1 GRIN2B PLEKHA6 CIT ADCY5 KCNQ2 SEPTIN7

3.65e-05347124817114649
Pubmed

SIRPα maintains macrophage homeostasis by interacting with PTK2B kinase in Mycobacterium tuberculosis infection and through autophagy and necroptosis.

SIRPB1 SIRPG

3.77e-053124236202053
Pubmed

Src homology 2 domain-containing protein tyrosine phosphatase substrate 1 regulates the migration of Langerhans cells from the epidermis to draining lymph nodes.

SIRPB1 SIRPG

3.77e-053124215034021
Pubmed

Novel mutations of MYO7A and USH1G in Israeli Arab families with Usher syndrome type 1.

MYO7A USH1G

3.77e-053124222219650
Pubmed

Imaging of Glioblastoma Tumor-Associated Myeloid Cells Using Nanobodies Targeting Signal Regulatory Protein Alpha.

SIRPB1 SIRPG

3.77e-053124234917090
Pubmed

Inhibitory regulation of osteoclast bone resorption by signal regulatory protein alpha.

SIRPB1 SIRPG

3.77e-053124219667119
Pubmed

SIRPA-Inhibited, Marrow-Derived Macrophages Engorge, Accumulate, and Differentiate in Antibody-Targeted Regression of Solid Tumors.

SIRPB1 SIRPG

3.77e-053124228669759
Pubmed

Critical role for protein tyrosine phosphatase SHP-1 in controlling infection of central nervous system glia and demyelination by Theiler's murine encephalomyelitis virus.

SIRPB1 SIRPG

3.77e-053124212134038
Pubmed

Central nervous system antigen P84 can serve as a substrate for neurite outgrowth.

SIRPB1 SIRPG

3.77e-05312422303162
Pubmed

SHPS-1 promotes the survival of circulating erythrocytes through inhibition of phagocytosis by splenic macrophages.

SIRPB1 SIRPG

3.77e-053124216141346
Pubmed

A role for SHPS-1/SIRPalpha in Concanavalin A-dependent production of MMP-9.

SIRPB1 SIRPG

3.77e-053124217825046
Pubmed

SIRPα deficiency accelerates the pathologic process in models of Parkinson disease.

SIRPB1 SIRPG

3.77e-053124231322787
Pubmed

The Rho kinase pathway regulates the migration of dendritic cells through SIRP-α.

SIRPB1 SIRPG

3.77e-053124222391241
Pubmed

Dynamic regulation of cAMP synthesis through anchored PKA-adenylyl cyclase V/VI complexes.

ADCY5 ADCY6

3.77e-053124216973443
Pubmed

Adenylyl cyclase 5 links changes in calcium homeostasis to cAMP-dependent cyst growth in polycystic liver disease.

ADCY5 ADCY6

3.77e-053124227826057
Pubmed

Expression of recipient CD47 on rat insulinoma cell xenografts prevents macrophage-mediated rejection through SIRPα inhibitory signaling in mice.

SIRPB1 SIRPG

3.77e-053124223472187
Pubmed

Deficiency in SIRP-α cytoplasmic recruitment confers protection from acute kidney injury.

SIRPB1 SIRPG

3.77e-053124231370677
Pubmed

A functional subset of CD8+ T cells during chronic exhaustion is defined by SIRPα expression.

SIRPB1 SIRPG

3.77e-053124230770827
Pubmed

Myosin 7 and its adaptors link cadherins to actin.

MYO7A USH1G

3.77e-053124228660889
Pubmed

Signal regulatory protein α protects podocytes through promoting autophagic activity.

SIRPB1 SIRPG

3.77e-053124230888336
Pubmed

Podocyte SIRPα reduction aggravates lupus nephritis via promoting T cell inflammatory responses.

SIRPB1 SIRPG

3.77e-053124238758648
Pubmed

Requirement of SIRPα for protective immunity against Leishmania major.

SIRPB1 SIRPG

3.77e-053124220854790
Pubmed

BIT, an immune antigen receptor-like molecule in the brain.

SIRPB1 SIRPG

3.77e-05312429271230
Pubmed

Gene structure of mouse BIT/SHPS-1.

SIRPB1 SIRPG

3.77e-053124210585853
Pubmed

Expression of Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 in pancreatic beta-Cells and its role in promotion of insulin secretion and protection against diabetes.

SIRPB1 SIRPG

3.77e-053124218635660
Pubmed

Resistance to collagen-induced arthritis in SHPS-1 mutant mice.

SIRPB1 SIRPG

3.77e-053124218455510
Pubmed

HERG K(+) currents in human prolactin-secreting adenoma cells.

KCNH7 KCNH6

3.77e-053124212634931
Pubmed

Signal regulatory protein alpha (SIRPalpha)/CD47 interaction and function.

SIRPB1 SIRPG

3.77e-053124219223164
Pubmed

Gq-mediated Ca2+ signals inhibit adenylyl cyclases 5/6 in vascular smooth muscle cells.

ADCY5 ADCY6

3.77e-053124219889965
Pubmed

Endothelial SIRPα signaling controls VE-cadherin endocytosis for thymic homing of progenitor cells.

SIRPB1 SIRPG

3.77e-053124235511221
Pubmed

Focal cerebral ischemia upregulates SHP-1 in reactive astrocytes in juvenile mice.

SIRPB1 SIRPG

3.77e-053124212742627
Pubmed

Dendritic cell SIRPα regulates homeostasis of dendritic cells in lymphoid organs.

SIRPB1 SIRPG

3.77e-053124225818708
Pubmed

Direct recording and molecular identification of the calcium channel of primary cilia.

PKD1L1 PKD1L2

3.77e-053124224336289
Pubmed

Non-Hematopoietic and Hematopoietic SIRPα Signaling Differently Regulates Murine B Cell Maturation in Bone Marrow and Spleen.

SIRPB1 SIRPG

3.77e-053124226222253
Pubmed

Negative regulation of platelet clearance and of the macrophage phagocytic response by the transmembrane glycoprotein SHPS-1.

SIRPB1 SIRPG

3.77e-053124212167615
Pubmed

Signal regulatory protein alpha initiates cachexia through muscle to adipose tissue crosstalk.

SIRPB1 SIRPG

3.77e-053124231507080
Pubmed

Developmentally regulated expression of the mouse homologues of the potassium channel encoding genes m-erg1, m-erg2 and m-erg3.

KCNH7 KCNH6

3.77e-053124214643686
Pubmed

Involvement of signal regulatory protein α, a negative regulator of Toll-like receptor signaling, in impairing the MyD88-independent pathway and intracellular killing of Burkholderia pseudomallei-infected mouse macrophages.

SIRPB1 SIRPG

3.77e-053124222988019
Pubmed

Hypothermia-induced tyrosine phosphorylation of SIRPα in the brain.

SIRPB1 SIRPG

3.77e-053124222468987
Pubmed

Effect of Serum Deprivation Stress on Signal Induction Regulatory Protein-Alpha (SIRP-Alpha)-Mediated Erythrophagocytosis by Macrophages.

SIRPB1 SIRPG

3.77e-053124230894504
Pubmed

Constitutive inhibitory G protein activity upon adenylyl cyclase-dependent cardiac contractility is limited to adenylyl cyclase type 6.

ADCY5 ADCY6

3.77e-053124231173603
Pubmed

SIRPα controls the activity of the phagocyte NADPH oxidase by restricting the expression of gp91(phox).

SIRPB1 SIRPG

3.77e-053124223022485
Pubmed

Anti-SIRPα antibody immunotherapy enhances neutrophil and macrophage antitumor activity.

SIRPB1 SIRPG

3.77e-053124229158380
Pubmed

Lack of non-hematopoietic SIRPα signaling disturbs the splenic marginal zone architecture resulting in accumulation and displacement of marginal zone B cells.

SIRPB1 SIRPG

3.77e-053124225817792
Pubmed

Deletion of SIRPα (signal regulatory protein-α) promotes phagocytic clearance of myelin debris in Wallerian degeneration, axon regeneration, and recovery from nerve injury.

SIRPB1 SIRPG

3.77e-053124231883525
Pubmed

Signal regulatory protein α is associated with tumor-polarized macrophages phenotype switch and plays a pivotal role in tumor progression.

SIRPB1 SIRPG

3.77e-053124223504854
Pubmed

SIRPα signaling regulates podocyte structure and function.

SIRPB1 SIRPG

3.77e-053124223842779
Pubmed

Essential roles of SIRPα in homeostatic regulation of skin dendritic cells.

SIRPB1 SIRPG

3.77e-053124220955735
Pubmed

Soluble SIRP-Alpha Promotes Murine Acute Lung Injury Through Suppressing Macrophage Phagocytosis.

SIRPB1 SIRPG

3.77e-053124235634325
Pubmed

The murine P84 neural adhesion molecule is SHPS-1, a member of the phosphatase-binding protein family.

SIRPB1 SIRPG

3.77e-05312429348339
Pubmed

Targeting SIRP-α protects from type 2-driven allergic airway inflammation.

SIRPB1 SIRPG

3.77e-053124221108471
Pubmed

Mutational analysis of the mechanism of negative regulation by SRC homology 2 domain-containing protein tyrosine phosphatase substrate-1 of phagocytosis in macrophages.

SIRPB1 SIRPG

3.77e-053124216920950
Pubmed

Src homology 2 domain-containing protein tyrosine phosphatase substrate 1 regulates the induction of Langerhans cell maturation.

SIRPB1 SIRPG

3.77e-053124217109464
Pubmed

Signal regulatory protein α negatively regulates mast-cell activation following FcεRI aggregation.

SIRPB1 SIRPG

3.77e-053124223504624
Pubmed

Signal regulatory protein alpha (SIRPα) regulates the homeostasis of CD103(+) CD11b(+) DCs in the intestinal lamina propria.

SIRPB1 SIRPG

3.77e-053124225236797
Pubmed

Loss of microglial SIRPα promotes synaptic pruning in preclinical models of neurodegeneration.

SIRPB1 SIRPG

3.77e-053124233795678
Pubmed

Chromosomal mapping of human adenylyl cyclase genes type III, type V and type VI.

ADCY5 ADCY6

3.77e-05312428034296
Pubmed

Resistance to experimental autoimmune encephalomyelitis and impaired T cell priming by dendritic cells in Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 mutant mice.

SIRPB1 SIRPG

3.77e-053124217617577
GeneFamilyDyneins, axonemal

DNAH10 DNAH2 DNAH17 DNAH5

1.42e-0617924536
GeneFamilyAdenylate cyclases|Deafness associated genes

ADCY5 ADCY6 ADCY7

1.49e-051092353
GeneFamilyPotassium voltage-gated channels

KCNH7 KCNH6 KCNQ1 KCNQ2

4.99e-0540924274
GeneFamilyCD molecules|V-set domain containing|C1-set domain containing|Signal regulatory proteins

SIRPB1 SIRPG

2.54e-045922747
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

NECTIN3 KIRREL1 ALCAM

1.10e-0340923592
GeneFamilyAdenosine receptors|V-set domain containing

SIRPB1 NECTIN3 SIRPG ALCAM TREML2

1.47e-03163925590
GeneFamilyImmunoglobulin like domain containing

DSCAM ICAM4 NECTIN3 KIRREL1 ALCAM

3.06e-03193925594
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 RELN DNAH10 LAMA1 GRIN2B PKD1L2 KCNQ2 DNAH5

4.93e-0818412482cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 RELN DNAH10 LAMA1 GRIN2B PKD1L2 KCNQ2 DNAH5

4.93e-081841248ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 RELN DNAH10 LAMA1 GRIN2B PKD1L2 KCNQ2 DNAH5

4.93e-0818412482b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|390C / Donor, Lineage, Cell class and subclass (all cells)

ABL2 PIEZO1 GAL3ST4 DNAH17 CARF ALCAM NEURL4

2.70e-07155124715bacd06cc2b02b13c85bb71c5b758e5ff613e80
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 ERF DSCAM DNAH10 LCN2 RNF17 DNAH5

4.85e-07169124712bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN TBC1D9B MYO7A EXPH5 FRS3 HEPH HHIPL2

5.46e-071721247b3c4adccc34bb9e4e78e40f4e2e23736c347cc75
ToppCellfacs-Lung-Endomucin-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN TBC1D9B MYO7A EXPH5 FRS3 HEPH HHIPL2

5.46e-0717212472f1673fcb2356684d60871debb0f159aec553a1c
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN DUOX2 LCN2 PTPRB SLC12A9 UGCG TRIM37

8.90e-07185124759acaf025353405948dc34ccccf37ec5c08ea903
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Hsd11b1_Endou|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CPNE8 FRAS1 IDO1 EXPH5 GDPD5 DNAH5

5.41e-061581246c8af8964a140acb2987e3b4906d72c546108d229
ToppCellfacs-Marrow-B-cells-18m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN SLC25A21 IDO1 EML6 KCNH6 ACMSD

6.94e-061651246361a605d8f833d9ec54b120480dce397da35f9c3
ToppCellfacs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC25A21 IDO1 ICAM4 KCNH6 FECH ACMSD

7.69e-06168124617fb9426eeea407b26fb895b8397faca95b7552d
ToppCellfacs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC25A21 IDO1 ICAM4 KCNH6 FECH ACMSD

7.69e-061681246a61b39884851384cffd430079040546d125b2b40
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IGHV3-48 IGKV1-17 IGKV1-6 IGHV3-11 EML6 IGHV3-64

1.04e-0517712464c434a7b7cc54cf4dac996bbc3f5124d9ef9a9cd
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGHV3-48 IGKV1-17 IGKV1-6 IGHV3-11 EML6 IGHV3-64

1.04e-051771246d746122bf8d208c3aa4d156e8c12d0a0e555c6e5
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DNAH10 AASDH HEPH EML5 HHAT KCNQ2

1.04e-0517712468abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGHV3-48 IGKV1-17 IGKV1-6 IGHV3-11 EML6 IGHV3-64

1.04e-051771246fc40918825b7e1eb6861df59dfca944778a64b98
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGHV3-48 IGKV1-17 IGKV1-6 IGHV3-11 EML6 IGHV3-64

1.10e-051791246837ed81f18257f444eaeadc4fac89deedd4e3061
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGHV3-48 IGKV1-17 IGKV1-6 IGHV3-11 EML6 IGHV3-64

1.10e-051791246494febe77c6d4e6a2c6f0928bbf4c84b0301f188
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGHV3-48 IGKV1-17 IGKV1-6 IGHV3-11 EML6 IGHV3-64

1.10e-051791246b6ee4f41d8fb5f047b7bdd8489dda0a89fc6d43f
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-2|TCGA-Skin / Sample_Type by Project: Shred V9

ABL2 LAMA1 COPS8 HHAT FECH TRIM37

1.18e-0518112469d5b331cabc5524f0a9fd8b571e87be4c447c7d4
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

THSD4 CPNE8 GRIN2B GDPD5 PTPRB HHAT

1.25e-051831246c1297d8eddfc7132e84ceef14f01b6281f9d0f6a
ToppCellLPS-IL1RA|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THSD4 IDO1 YBX3 PTPRB MIB1 N4BP1

1.29e-051841246c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCellhealthy_donor-Lymphocytic-Plasma_cell-IgA_Plasmablast|healthy_donor / Disease condition, Lineage, Cell class and subclass

IGHV3-48 IGKV1-17 IGKV1-6 IGHV3-11 EML6 IGHV3-64

1.37e-051861246e2c050ba02e1f84f0b7258dc92e7ff6ab349ff67
ToppCellhealthy_donor-Lymphocytic-Plasma_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

IGHV3-48 IGKV1-17 IGKV1-6 IGHV3-11 EML6 IGHV3-64

1.46e-051881246bd53b0371154cff680226897b61c9809a239d1b6
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

THSD4 WSB1 EXPH5 ALCAM DNAH5 SCAI

1.46e-051881246707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 WSB1 FRAS1 EML6 GRIN2B KCNQ1

1.55e-05190124611d3c31167ea71809b4cc3757a0c6ea54a448602
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 WSB1 FRAS1 EML6 GRIN2B KCNQ1

1.64e-051921246fd08ae787e936cfdb1ab8f19b0fd63005b462709
ToppCellCiliated-cil-3|World / Class top

DNAH10 DYNC2H1 DNAH2 PPP1R13B PIERCE1 DNAH5

1.64e-0519212464989ebb8812b8af1870599acd932849122c05a29
ToppCelldroplet-Kidney-nan-18m-Endothelial-kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 CPNE8 IDO1 GASK1B PTPRB TRIM37

1.64e-051921246144503af50274eaed5cf6effa892c640eab28663
ToppCelldroplet-Kidney-nan-18m-Endothelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 CPNE8 IDO1 GASK1B PTPRB TRIM37

1.64e-051921246c96736bb3a6bb052678b1b078f7823063ca69e6d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 WSB1 FRAS1 EML6 GRIN2B KCNQ1

1.64e-051921246bae236c9f1fac77bce28d0a9cf090100d391ff77
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IDO1 LGALS9B EXPH5 LCN2 UGCG DNAH5

1.85e-051961246b07db4a53ab9be9aad6fae5e45f9547db829d096
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IDO1 LGALS9B EXPH5 LCN2 UGCG DNAH5

1.85e-051961246c366f980cc04abfe1c0c14746c11810c812a42c0
ToppCellCOVID-19-Epithelial|COVID-19 / Condition, Lineage and Cell class

DNAH10 EXPH5 DNAH2 LCN2 PIERCE1 DNAH5

1.90e-05197124618fd7344628a87d5c7ef5efb66e260a4136245bf
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

MYO7A DYNC2H1 PLEKHA6 VIT EML5 HHAT

1.95e-0519812460c4d2c68a42f8a9e964e2dd28092fe75f5216834
ToppCellcritical-Epithelial|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

EXPH5 DUOX2 YBX3 LCN2 PIERCE1 ALCAM

2.01e-051991246bbb44e2a52f102a6d891ead6c06d6c07221abd33
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FRAS1 EXPH5 ICAM4 EML5 SLC12A9 LPIN2

2.01e-051991246a270630626df614f8605abddb7dee7c4d74f6149
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-DC-DC3-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IDO1 PACSIN1 EXPH5 UGCG NEURL4 TREML2

2.01e-0519912467271dbeca9aa838b88ad44d00059263a29c0316b
ToppCellNS-critical-d_16-33-Epithelial|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EXPH5 YBX3 LCN2 PIERCE1 ALCAM DNAH5

2.01e-0519912463b68197ec01c5f2b315d9e9b6eb02d5f6b5b77a3
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Pvrl3|Hippocampus / BrainAtlas - Mouse McCarroll V32

THSD4 EXPH5 ACTN2 NECTIN3 VIT

2.85e-0512712459bc55cb9f4bddb274930784d12a83b9dceb35cb7
ToppCellCOVID-19_Mild-Neu_0|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients

ABL2 CEMIP2 SLC12A9 KCNQ1

2.89e-056312441ab77b6f098686bc168427159282bbf3538d4292
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Pvrl3-Excitatory_Neuron.Slc17a7.Pvrl3-Nos1_(CA3_Principal_cells)|Hippocampus / BrainAtlas - Mouse McCarroll V32

ASB17 EXPH5 ACTN2 NECTIN3 VIT

2.96e-0512812459128b633879d21de2ebe651384cfec6d2c3c2932
ToppCellAT1-AT2_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

THSD4 EXPH5 NECTIN3 CIT SCAI

4.54e-05140124545d52a086ced8d58e01ac51ac4a90338e8649b16
ToppCellBAL-Control-cDC_4|Control / Compartment, Disease Groups and Clusters

PEX12 ADGRL1 AGO1 PIERCE1 HHAT

5.37e-0514512453b2a2965dc18abd39d5ed70c0fcad0210e7f12c8
ToppCell10x5'-blood-Lymphocytic_B_plasma-Plasma_cells|blood / Manually curated celltypes from each tissue

THSD4 IGHV3-48 IGKV1-6 IGHV3-11 IGHV3-64

5.73e-05147124558089378fac1743ce99dc4f1bd7b5253a927f050
ToppCellE12.5-Hematopoietic-Erythroid-enucleate_erythrocyte|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SLC25A21 ICAM4 FECH TSPO ACMSD

6.11e-051491245fb75c1b91b8a0c8221fbbc350666799727b21120
ToppCellE12.5-Hematopoietic-Erythroid|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SLC25A21 ICAM4 FECH TSPO ACMSD

6.11e-05149124508e7f76b7e4b53ff734d50dbc853ecfdeb4b371b
ToppCell10x5'-blood-Lymphocytic_B_plasma|blood / Manually curated celltypes from each tissue

THSD4 IGHV3-48 IGKV1-6 IGHV3-11 IGHV3-64

6.30e-0515012456bab0a8bf78ed7de9e1b67ede7496488f80f4863
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4/8-lo-Trm_Tgd|lymph-node_spleen / Manually curated celltypes from each tissue

DYNC2H1 SLC25A14 ADGRL1 PIERCE1 DCLRE1A

7.36e-051551245b0e456c4915076e1d38282e116a6eb3230ae80dc
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Lypd1_Gpr88|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FRAS1 DNAH10 IDO1 EXPH5 ADCY7

7.82e-0515712455aee90ad7aaa65fdabc23597451da5e48db8f4e6
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IDO1 CEMIP2 KCNH6 GDPD5 PTPRB

7.82e-0515712452c946c6ab284fac3c25db688ed0aabe5a3f9ffa5
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage|356C / Donor, Lineage, Cell class and subclass (all cells)

THSD4 SIRPB1 ADCY6 EML5 PIERCE1

8.30e-05159124524f87c666eff10c1844c900ffd7ad49fa9f80481
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CPNE8 GASK1B CEMIP2 SLC25A32 PTPRB

8.81e-051611245f4f5d6eaa32169de699c8ff8e8ae35179c8e25c0
ToppCell368C-Lymphocytic-Plasma_cell-|368C / Donor, Lineage, Cell class and subclass (all cells)

IGHV3-48 IGKV1-17 IGKV1-6 IGHV3-11 PACSIN1

9.07e-051621245c21a54310b239d999bbc9d8fb5e8fda16e0bc336
ToppCell368C-Lymphocytic-Plasma_cell|368C / Donor, Lineage, Cell class and subclass (all cells)

IGHV3-48 IGKV1-17 IGKV1-6 IGHV3-11 PACSIN1

9.07e-051621245f945688815229c8386cbcbf46deee7df316fa8d3
ToppCellT_cells-Tph_and_Tfh|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

LGALS9B MYO7A ARID5A CEMIP2 SIRPG

9.07e-051621245146058f2d60846376078916055d08f68562e3a7c
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 DNAH10 GAL3ST4 RNF17 ADCY7

9.33e-0516312458dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 DNAH10 GAL3ST4 RNF17 ADCY7

9.33e-051631245fd243ca223079033be480a24817a399f281fa4d4
ToppCell368C-Myeloid-Dendritic-cDC_activated|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

IDO1 DNAH2 ADCY6 C7orf25 RNF180

9.61e-05164124567c636a2cc32e56c6186dc7e779cc19af04639d2
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_LINC00507_PSRC1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CPNE8 DGKA NECTIN3 PPP4R4 DNAH5

9.89e-0516512456de69b75174731931e7e80a3488f983a7ba4defe
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor-epi-prox-progenitor_intermediate_|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FRAS1 PPP1R13B ADCY7 PPP4R4 ALCAM

9.89e-051651245f6887c64af0f26e33316bc5587487e24d76ece2a
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-SELL+_CD4_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DGKA SIRPB1 SIRPG DNAH17 HHIPL2

1.05e-041671245484de3ca4a905067c18d06995601479eef8fc15e
ToppCell10x5'-Lung-Myeloid_Dendritic-pDC|Lung / Manually curated celltypes from each tissue

PACSIN1 ACTN2 PLEKHA6 UGCG KCNQ2

1.08e-04168124590f713dae3fcbd6ca801a019e3861c263ff3366b
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ICAM4 GRIN2B CIT PPP4R4 KCNQ2

1.08e-041681245b87fc63f9e35dfcfc46cb129ea569e73c5e018bb
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ICAM4 GRIN2B CIT PPP4R4 KCNQ2

1.08e-041681245b96a48552f4236a95bbcdce2f1b05041086d7101
ToppCellSmart-seq2-blood_(Smart-seq2)|Smart-seq2 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

YBX3 GASK1B SLC12A9 TSPO LRP1

1.11e-0416912450ee74cc97a2db9cc16dc73424f74747afe13af90
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CPNE8 IDO1 CEMIP2 PTPRB KCNQ1

1.14e-041701245af8b56555cbd5a1016ab9ec2ce88225c58c89648
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA1 UGCG KCNQ2 ACMSD DNAH5

1.20e-0417212450c2d0bb767e5ce089b42ad49e8b303a103de2d5c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA1 UGCG KCNQ2 ACMSD DNAH5

1.20e-041721245eeed177a03c116e9815a8e086d24efc9643b16a4
ToppCellfacs-Heart-LV-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ICAM4 CIT CEMIP2 PPP4R4 MIB1

1.20e-041721245f2c17c49b375b28ad47dc6cabda62f1c238023dd
ToppCellfacs-Heart-LV-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ICAM4 CIT CEMIP2 PPP4R4 MIB1

1.20e-0417212456ab4f01098dddb789df298ddf97b3c384405ee6c
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CPNE8 IDO1 CEMIP2 PTPRB KCNQ1

1.20e-0417212459a1743abcd5fbd38253ea84d88ad716cfb71de36
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 DYNC2H1 DNAH2 PIERCE1 DNAH5

1.23e-041731245c3762655caa79ac4879876f470d32578a3c93b01
ToppCellsevere-B_memory|severe / disease stage, cell group and cell class

IGKV1-17 EML6 GDPD5 HHAT CNOT1

1.23e-0417312453a987ac53a0136cc4c70ce8b901a15fc00c795e1
ToppCellwk_15-18-Mesenchymal-Fibroblast-Mesenchymal_3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

THSD4 RELN G2E3 ACTN2 GASK1B

1.23e-041731245b43817a6b1ed8d6b5366702343be4311c0d52d83
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WSB1 PLEKHA6 CEMIP2 LRP1 ALCAM

1.30e-041751245cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCellsevere-B_memory|World / disease stage, cell group and cell class

IGKV1-17 EML6 HHAT CNOT1 IGHV3-64

1.34e-0417612454e5c6b1aa5ffd13593a6bcd1e1253c1737c5c2b4
ToppCellControl-Lymphoid_P-Plasmablast|Control / Disease group, lineage and cell class

IGHV3-48 IGKV1-17 IGKV1-6 IGHV3-11 EML6

1.34e-0417612454b4416f342b732d2cc60133838728880326257d8
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THSD4 RELN DUOX2 LCN2 TRIM37

1.34e-041761245460cb302c5b3d609c65b924e1d4e8ea057a68485
ToppCellControl-Lymphoid_P|Control / Disease group, lineage and cell class

IGHV3-48 IGKV1-17 IGKV1-6 IGHV3-11 EML6

1.34e-041761245d895a6b295cd649273ff80ad7785a3e0ae4c728a
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-nan|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WSB1 CPNE8 USP9X NECTIN3 LPIN2

1.34e-0417612451dd54bfaa58541de51e5a8328651d390833bd480
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IGHV3-48 IGKV1-17 IGKV1-6 IGHV3-11 IGHV3-64

1.37e-041771245c2b0fb5921eea24d248d6e6ccb57c29b0832602c
ToppCellPND07-28-samps-Endothelial-Postnatal_endothelial-endothelial_cells_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

IDO1 ADGRL1 CEMIP2 GDPD5 PTPRB

1.37e-0417712456da88c358b3a2e47fa3472217a38b6b00ad7b280
ToppCellEndothelial-Endothelial-C|Endothelial / shred on cell class and cell subclass (v4)

PCSK5 PEX12 GASK1B CEMIP2 PTPRB

1.37e-041771245b5b9278dfd76b1aacd88e5fe86e91a2c9b565f87
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IGHV3-48 IGKV1-17 IGKV1-6 IGHV3-11 IGHV3-64

1.37e-041771245111fb0707ff37ca631d85bb5a09e067ffe568eb8
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC25A21 MYO7A DNAH2 PIERCE1 DNAH5

1.41e-0417812456178706db4a855d72abc156537604d575624df56
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC25A21 MYO7A DNAH2 PIERCE1 DNAH5

1.41e-041781245f02076ece0fa899e620971c887ad4da7f48684ed
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-pDC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PACSIN1 SIRPB1 SIRPG UGCG TREML2

1.41e-041781245b7d1d8f76c1c2467b1a39a9b4150ed4a47144a15
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-goblet-BEST2+_Goblet_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LGALS9B EXPH5 DUOX2 PLEKHA6 HHIPL2

1.45e-041791245c833ded1f9e87be2ba2037820d92a389560b711c
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ICAM4 ADGRL1 GRIN2B CIT KCNQ2

1.45e-041791245a3922476f33d2e4137a12dbda21a1703dff79684
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

DOCK2 GRIN2B CEMIP2 UGCG ALCAM

1.45e-04179124514fc8ccb6b215063d747643f47d780d2b237eb67
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

WSB1 FRAS1 KCNH7 DYNC2H1 EXPH5

1.45e-041791245666072c0e8448dbaec1683d18368ec2502453f90
ToppCellfacs-Heart-RA-24m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 LCN2 CEMIP2 PTPRB TRIM37

1.49e-041801245174c643e046646e3b305dd7e5b120d2c9a46690f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WSB1 FRAS1 KCNH7 EML6 KCNQ1

1.49e-041801245788d5fbf688365b5d92d3aa19b9f8e9448f8be5a
ToppCellfacs-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA1 GASK1B CEMIP2 PTPRB TRIM37

1.52e-04181124572c28baf4fd417ff4a7068603830d55074960144
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE8 RELN LCN2 CEMIP2 PTPRB

1.52e-041811245cef034030e6b029a49ae56be37ea1fac1a5c350e
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCSK5 CIT CEMIP2 PTPRB C7orf25

1.52e-041811245136b0c60680068838d184d32aa99d7bea8718dbc
ToppCellfacs-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA1 GASK1B CEMIP2 PTPRB TRIM37

1.52e-0418112452ac4d3e8987d5a009d7908d8787e18165826202a
ToppCellfacs-Lung-3m-Endothelial-venous_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMA1 GASK1B CEMIP2 PTPRB TRIM37

1.52e-0418112452628c7ac345eaaeecf8e34617e81948925962cb9
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 IDO1 ACTN2 PPP4R4 KCNQ2

1.56e-041821245d41ff834b8fc1d0e23cac7ae261de5f72874e462
DrugBiliton

DNAH10 MYO7A DNAH17 DNAH5 TRIM37

2.41e-06411205CID000002974
DrugAC1L1EV8

ADCY5 ADCY6 ADCY7

7.84e-0681203CID000002964
DrugIsocarboxazid [59-63-2]; Up 200; 17.2uM; PC3; HT_HG-U133A

ACTN2 ADCY6 ARID5A PPP4R4 PTPRB DNAH17 N4BP1 HCFC1

8.62e-0619312083684_UP
DrugMethylprednisolone, 6-alpha [83-43-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A

WSB1 TBC1D9B ARFGEF2 ADCY6 ADCY7 COPS8 ALCAM CABIN1

9.64e-0619612083183_DN
DrugTriprolidine hydrochloride [550-70-9]; Up 200; 12.8uM; HL60; HT_HG-U133A

ABL2 DSCAM MYO7A PACSIN1 DYNC2H1 DNAH17 LPIN2 HCFC1

1.08e-0519912082376_UP
Drug14,15-dihydroforskolin

ADCY5 ADCY6 ADCY7

1.17e-0591203CID000194193
Drugetazolate

ADCY5 ADCY6 ADCY7 TSPO

1.57e-05291204CID000003277
Drug2',5'-dd3'-FSBA

ADCY5 ADCY6 ADCY7

1.67e-05101203CID003081206
DrugNC-5Z

ADCY5 ADCY6 ADCY7

1.67e-05101203CID003035914
DrugArgipressin

SAR1A ADCY5 ADCY6 ADCY7 PYGB

1.90e-05621205CID000008230
DrugAC1L40QM

ADCY5 ADCY6 ADCY7

2.28e-05111203CID000099213
DrugB-Mlvp

ADCY5 ADCY6 ADCY7

2.28e-05111203CID000195648
DrugAC1NY9KD

ADCY5 ADCY6 ADCY7

2.28e-05111203CID005771741
DrugXE991

KCNH7 KCNH6 KCNQ1 KCNQ2

2.67e-05331204CID000656732
Drugcisapride

KCNH7 ADCY5 ADCY6 ADCY7 KCNH6 KCNQ1

2.87e-051121206CID000002769
DrugFCE 23884

ADCY5 ADCY6 ADCY7

3.93e-05131203CID000065898
DrugAC1L1BJN

ADCY5 ADCY6 ADCY7

3.93e-05131203CID000001467
Drugsclareol glycol

ADCY5 ADCY6 ADCY7

3.93e-05131203CID000091915
Drugnantradol hydrochloride

ADCY5 ADCY6 ADCY7

3.93e-05131203CID000047652
Drugpractolol

SAR1A ADCY5 ADCY6 ADCY7

4.24e-05371204CID000004883
DrugSKF 75670

ADCY5 ADCY6 ADCY7

6.20e-05151203CID000173870
DrugBMY 42393

ADCY5 ADCY6 ADCY7

6.20e-05151203CID000131961
DrugAC1L2AAS

ADCY5 ADCY6 ADCY7

6.20e-05151203CID000068714
DrugN6-(phenylisopropyl)adenosine

ADCY5 ADCY6 ADCY7 PYGB

6.39e-05411204CID000034507
Drug2',3'-dideoxyadenosine

SAR1A ADCY5 ADCY6 ADCY7 PYGB

7.38e-05821205CID000020039
Druglinopirdine

KCNH7 KCNH6 KCNQ1 KCNQ2

7.73e-05431204CID000003932
DrugNiacin [59-67-6]; Up 200; 32.4uM; HL60; HT_HG-U133A

DSCAM MYO7A PPP1R13B GAL3ST4 GASK1B PPP4R4 KCNQ1

7.73e-0519412073043_UP
DrugUrsolic acid [77-52-1]; Down 200; 8.8uM; PC3; HT_HG-U133A

ERF ADGRL1 ADCY7 GDPD5 FECH DCLRE1A CABIN1

7.98e-0519512075825_DN
Druglinopirdine

KCNQ1 KCNQ2

8.24e-0531202ctd:C061017
DrugFARNESYL DIPHOSPHATE

FNTA FDPS

8.24e-0531202DB07780
Drug(R)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide

KCNQ1 KCNQ2

8.24e-0531202ctd:C576869
DrugApomorphine hydrochloride hemihydrate [41372-20-7]; Up 200; 6.4uM; PC3; HG-U133A

ABL2 PIEZO1 GAL3ST4 ADCY6 PYGB N4BP1 CABIN1

8.24e-0519612071923_UP
Drugamphotericin B solution

KCNH7 ADCY5 ADCY6 ADCY7 KCNH6

8.28e-05841205CID000001972
DrugReserpine [50-55-5]; Up 200; 6.6uM; MCF7; HT_HG-U133A

WSB1 FRAS1 PACSIN1 NECTIN3 GASK1B HHAT DNAH17

8.78e-0519812073341_UP
DrugIopamidol [60166-93-0]; Up 200; 5.2uM; PC3; HT_HG-U133A

SLC25A21 TBC1D9B ABL2 CEMIP2 PPP4R4 KCNH6 PIERCE1

8.78e-0519812075832_UP
DrugPicotamide monohydrate [80530-63-8]; Down 200; 10.2uM; PC3; HT_HG-U133A

PPP1R13B SAR1A CEMIP2 COPS8 C7orf25 KIRREL1 N4BP1

9.06e-0519912077140_DN
DrugDioxybenzone [131-53-3]; Up 200; 16.4uM; HL60; HT_HG-U133A

RELN DSCAM EXPH5 PPP1R13B PLEKHA6 KCNH6 DNAH17

9.06e-0519912073101_UP
DrugPiroxicam [36322-90-4]; Down 200; 12uM; MCF7; HT_HG-U133A

DSCAM DGKA ADGRL1 ADCY7 PPP4R4 CABIN1 HCFC1

9.06e-0519912072252_DN
DrugSan 21009

ADCY5 ADCY6 ADCY7

9.20e-05171203CID000152662
DrugU754

ADCY5 ADCY6 ADCY7

9.20e-05171203CID000062824
Drugfentanyl isothiocyanate

ADCY5 ADCY6 ADCY7

9.20e-05171203CID000084008
Drugfurosemide

GRIN2B SAR1A ADCY5 ADCY6 ADCY7 SLC12A9 TSPO SLC4A9

9.92e-052721208CID000003440
DrugDiC8

SLC25A21 DGKA ADCY5 ADCY6 ADCY7 KCNQ2

1.26e-041461206CID000001323
DrugRo 41-9067

ADCY5 ADCY6 ADCY7

1.30e-04191203CID000125800
DrugAC1L3XQA

ADCY5 ADCY6 ADCY7

1.30e-04191203CID000124009
DrugMK-499

KCNH7 KCNH6 KCNQ1

1.30e-04191203CID000127718
DrugSK&F 82958

ADCY5 ADCY6 ADCY7

1.30e-04191203ctd:C071262
DrugAC1L1FA8

GRIN2B ADCY5 ADCY6 ADCY7

1.40e-04501204CID000003150
DrugNSC97113

ADCY5 ADCY6 ADCY7 PYGB

1.51e-04511204CID000001869
DrugDvdavp

ADCY5 ADCY6 ADCY7

1.52e-04201203CID006441676
DrugYM435

ADCY5 ADCY6 ADCY7

1.52e-04201203CID000132119
DrugIC261

DNAH10 MYO7A DNAH17 KCNQ1 DNAH5

1.56e-04961205CID000003674
DrugEthylnitrosourea

PCSK5 RELN MYO7A DYNC2H1 FECH UGCG KCNQ1 KCNQ2

1.58e-042911208ctd:D005038
DrugAC1L1EKQ

GRIN2B ADCY5 ADCY6 ADCY7

1.63e-04521204CID000002834
DrugLI-W

ICAM4 ADGRL1

1.64e-0441202CID015991564
Drug10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone

KCNQ1 KCNQ2

1.64e-0441202ctd:C112297
DrugGERANYLGERANYL DIPHOSPHATE

FNTA FDPS

1.64e-0441202DB07841
Druglead fluoride

SLC25A32 TSPO

1.64e-0441202CID000024549
Drugpropanol

GRIN2B ADCY5 ADCY6 ADCY7

1.76e-04531204CID000001031
Drugindapamide

ADCY5 ADCY6 ADCY7 KCNQ1

1.76e-04531204CID000003702
Drug6-fluoronorepinephrine

ADCY5 ADCY6 ADCY7

1.77e-04211203CID000001862
Drugreproterol

ADCY5 ADCY6 ADCY7

1.77e-04211203CID000025654
DrugI-Q-S

WSB1 LAMA1 DUOX2 ADCY5 ADCY6 ADCY7

1.80e-041561206CID000003540
DrugE 4031

KCNH7 KCNH6 KCNQ1 KCNQ2

1.89e-04541204CID000003184
DrugGSK835726

ADCY5 ADCY6 ADCY7

2.04e-04221203CID005311268
Diseaselong QT syndrome (implicated_via_orthology)

KCNH7 KCNH6 KCNQ1 KCNQ2

5.73e-08101224DOID:2843 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

KCNH7 GRIN2B CIT KCNH6 MIB1 LRP1

6.17e-051631226DOID:1826 (implicated_via_orthology)
DiseaseSchizophrenia

RELN LAMA1 SIRPB1 GRIN2B PLEKHA6 LCN2 ADCY7 KCNH6 EML5 HHAT LRP1 KCNQ2 SEPTIN7

7.70e-0588312213C0036341
Diseasecoronary artery disease

SLC25A21 KCNH7 DSCAM DNAH10 DYNC2H1 ARFGEF2 DUOX2 YBX3 GDPD5 COPS8 HHAT CARF LRP1 ALCAM CABIN1

1.25e-04119412215EFO_0001645
DiseaseUsher syndrome, type 1A

MYO7A USH1G

1.68e-0451222C2931205
DiseaseUSHER SYNDROME, TYPE IB (disorder)

MYO7A USH1G

1.68e-0451222C1848638
DiseaseUSHER SYNDROME, TYPE IA, FORMERLY

MYO7A USH1G

1.68e-0451222C1848639
DiseaseUSHER SYNDROME, TYPE I, FRENCH VARIETY, FORMERLY

MYO7A USH1G

1.68e-0451222C1848640
DiseaseUsher syndrome type 1

MYO7A USH1G

1.68e-0451222cv:C1568247
DiseaseVACTERL association (implicated_via_orthology)

PCSK5 DYNC2H1

2.52e-0461222DOID:14679 (implicated_via_orthology)
DiseaseUsher Syndrome, Type I

MYO7A USH1G

2.52e-0461222C1568247
Diseaseheart conduction disease (implicated_via_orthology)

KCNH7 KCNH6 KCNQ2

3.13e-04321223DOID:10273 (implicated_via_orthology)
DiseaseHereditary retinal dystrophy

MYO7A USH1G

3.51e-0471222C0154860
Diseasequinolinate measurement

IDO1 ACMSD

3.51e-0471222EFO_0800175
DiseaseUsher syndrome

MYO7A USH1G

3.51e-0471222cv:C0271097
Diseasemigraine disorder, Headache

CARF FECH LRP1 FGF6

4.55e-04861224HP_0002315, MONDO_0005277
Diseasesignal-regulatory protein beta-1 measurement

SIRPB1 SIRPG

5.99e-0491222EFO_0802069
DiseaseNeurodevelopmental Disorders

DSCAM GRIN2B ADCY5 KCNQ2

6.11e-04931224C1535926
Diseaseage at onset, multiple sclerosis

PCSK5 RELN

7.47e-04101222EFO_0004847, MONDO_0005301
DiseaseCiliopathies

MYO7A DYNC2H1 USH1G DNAH5

1.15e-031101224C4277690
DiseaseCongenital Hypothyroidism

FOXE1 DUOX2

1.28e-03131222C0010308
Diseasesubstance-related disorder

PPP1R13B USP4 SCAI

1.31e-03521223MONDO_0002494
Diseasecongenital hypothyroidism (implicated_via_orthology)

FOXE1 DUOX2

1.49e-03141222DOID:0050328 (implicated_via_orthology)
Diseasebody weights and measures, parental genotype effect measurement

ADCY5 KCNQ1

1.49e-03141222EFO_0004324, EFO_0005939
DiseaseSitus ambiguus

PKD1L1 DNAH5

1.72e-03151222C0266642
Diseaseresponse to acetylsalicylate

SLC25A21 KCNQ1

1.96e-03161222GO_1903492
Diseasemigraine without aura, susceptibility to, 4

LRP1 FGF6

1.96e-03161222MONDO_0011847
Diseasebitter alcoholic beverage consumption measurement

CPNE8 RELN DNAH2 PPP1R13B

2.30e-031331224EFO_0010092
DiseaseHeadache

HHAT LRP1 FGF6

2.39e-03641223HP_0002315
Diseaseprimary ciliary dyskinesia (implicated_via_orthology)

PCSK5 DNAH5

2.77e-03191222DOID:9562 (implicated_via_orthology)
Diseaseevent free survival time, urinary bladder cancer

G2E3 GRIN2B

2.77e-03191222EFO_0000482, MONDO_0001187
Diseasetemporal lobe epilepsy (is_marker_for)

RELN GRIN2B

3.07e-03201222DOID:3328 (is_marker_for)
DiseaseAntimigraine preparation use measurement

LRP1 FGF6

3.38e-03211222EFO_0009939
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

RELN DNAH10 ADCY5 LRP1 ALCAM ACMSD

4.13e-033641226EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946

Protein segments in the cluster

PeptideGeneStartEntry
VRQGTYANPKEWGRA

USH1G

256

Q495M9
HYWVPAKRLFGGQIV

ACOT8

46

O14734
LLRKEEYQGVIAWQG

ERF

36

P50548
FGGLIQDVRRKVPWY

SLC4A9

386

Q96Q91
TGRRLWKNVYDELGG

ARID5A

106

Q03989
IAGAWQRLEQAEKGY

ACTN2

371

P35609
GEKLRVLGYNQNGEW

ABL2

131

P42684
VIGARKPQYDIWGNT

ADCY6

1096

O43306
GLWVIYATEGNNGRL

ADGRL1

276

O94910
GRPVNVCVGKEWYRF

ALG9

461

Q9H6U8
PYTGAVKVGAIQRWL

ERP29

131

P30040
WRLQEGRGEAVYQIG

GTPBP2

91

Q9BX10
GVNWESGYLVGIKRQ

FGF6

71

P10767
RGKQFYNGIEIKVWA

AGO1

436

Q9UL18
NYEQRTVLWRAGFKG

ARFGEF2

1631

Q9Y6D5
DLKKRFGYGGWVQLQ

ACMSD

16

Q8TDX5
WRGEGNKTQIFNVYG

AASDH

331

Q4L235
NVLLVQGYLAKSGWG

DCP2

111

Q8IU60
VIGARKPQYDIWGNT

ADCY7

1001

P51828
AGVIGARKPQYDIWG

ADCY5

1186

O95622
NKRGQQGWDRKYIVL

CIT

1456

O14578
WARLGDREGYVPKNL

PPP1R13B

1061

Q96KQ4
TIWKLDGLRGLYQGV

SLC25A32

71

Q9H2D1
RNEKGYGPATQVRWL

HCFC1

1986

P51610
VGYARQIIKKEGWGL

SLC25A21

151

Q9BQT8
PGWFRGYRTQKAVSV

PIERCE1

41

Q5BN46
GLIIVNAWYGKFVND

DNAJC11

461

Q9NVH1
RIYLSGWKGNPQLSD

IDO1

231

P14902
EWRFQGLVPGRKYVL

PTPRB

1226

P23467
VQGRVYNFLERPTGW

KCNQ1

106

P51787
FSKGQILYGRVLWNP

FRAS1

3691

Q86XX4
KGYGPATQVRWLQGN

HCFC2

771

Q9Y5Z7
IRQAPGKGLEWVSYI

IGHV3-11

56

P01762
WVRQAPGKGLEYVSA

IGHV3-64

56

A0A075B6Q5
GWLDSLGQQIGKRYN

KCNH7

586

Q9NS40
YKVLNRRKGPAVWGL

MTO1

111

Q9Y2Z2
LTRRGQICWYQKPGV

FDPS

176

P14324
FINGRNLGRYWNIGP

GLB1L3

601

Q8NCI6
LVAGVVFWYKRRVQG

LRP1

4436

Q07954
IVKRPSLQFLGQWGY

ASB17

26

Q8WXJ9
YVVCNTRQKGRWGPE

LGALS9B

71

Q3B8N2
WLDSLGVQLGKRYNG

KCNH6

436

Q9H252
KNLVDAGGVLRWYVQ

CARF

356

Q8N187
RPQGFEYKSGQWVRI

DUOX2

1291

Q9NRD8
VRQAPGKGLEWVSYI

IGHV3-48

56

P01763
NIEGAWKRGYTGKNI

PCSK5

151

Q92824
GDKYPQTWNGRLLAA

KCNQ2

281

O43526
GGKQGQRVLWKFQYI

DGKA

386

P23743
EQRRFGQGPFWGQEK

EXPH5

471

Q8NEV8
VLQKWRLGGIRSYNP

GDPD5

516

Q8WTR4
SLWARIEKYGQGRLQ

GAL3ST4

376

Q96RP7
GAKFLQYWGRIGSEN

RELN

2946

P78509
QRQGYPIWGKLTVYR

PKD1L2

2086

Q7Z442
LWDNGAKNLYRVGFE

MIB1

196

Q86YT6
RWRQLIEKGPQYGSL

PACSIN1

66

Q9BY11
FLGGNEVGKTYWNRI

HHAT

446

Q5VTY9
QFQGKWYVVGLAGNA

LCN2

46

P80188
YAQGANLVKIGERPW

GASK1B

166

Q6UWH4
IWQRGKEEEGVYGFL

G2E3

51

Q7L622
QRKWVYLEPIFGRGA

DYNC2H1

1346

Q8NCM8
NIYQQEGTRGLWKGV

SLC25A30

151

Q5SVS4
VWQQGQKGVAYDLGR

CABIN1

1866

Q9Y6J0
NYLVRWGSRGFPKEI

DOCK2

256

Q92608
RKFVGNLELIVGWYN

DNAH17

711

Q9UFH2
WLGRGQYGDKSIIEQ

C7orf25

131

Q9BPX7
NYIQVELKGWGGDRP

FRS3

416

O43559
WFIFDYIQLRGVQGG

UGCG

326

Q16739
GLGYRQAWALVGVID

CEMIP2

341

Q9UHN6
ATANPEILGYRWAKG

KIRREL1

246

Q96J84
IRNDLGWYQQKPGKA

IGKV1-6

51

A0A0C4DH72
IRNDLGWYQQKPGKA

IGKV1-17

51

P01599
SVGQRIWQRDFPGIY

COPS8

76

Q99627
LNGDIYVWKGINLIR

EML5

216

Q05BV3
LNGDIYVWKGLNLVR

EML6

216

Q6ZMW3
GKYNQILAFRPTGWT

DCLRE1A

951

Q6PJP8
EQYRRIGGGSPIKIW

FECH

121

P22830
EEVDLILKGGNYGWR

HHIPL2

451

Q6UWX4
VQERRKFGKIGWNVY

DNAH10

4031

Q8IVF4
VRGLYLEGAGWDRKN

DNAH2

4331

Q9P225
GNITWYRNGKVLHPL

ALCAM

166

Q13740
WPKALLGRAVFQGYS

PKD1L1

1131

Q8TDX9
YVQGVGNKEWREFGR

CPNE8

51

Q86YQ8
KNVWAVLDLYGPVRG

NEURL4

1066

Q96JN8
QERRKFGALGWNIPY

DNAH5

4196

Q8TE73
ERWLQKQGKYSGVGL

RNF180

391

Q86T96
RQGKTLRGPGWVSYQ

ICAM4

86

Q14773
SWYRNGEILNPGKNV

DSCAM

346

O60469
AYQILQGNGDLKRKW

USP9X

2401

Q93008
LCWRLKVYPDGNGVV

TRIM37

306

O94972
GFARVWVKGPRYLLQ

TREML2

66

Q5T2D2
IEQLGQGKSYWNRLR

PPP4R4

571

Q6NUP7
REAGRPGKGNYWALD

FOXE1

116

O00358
AWNYLKGILQDRGLS

FNTA

276

P49354
FLNGKSIGLWNYIER

LAMA1

2276

P25391
GIRDVQWNYAPKGRN

HEPH

31

Q9BQS7
LKRQGYGEGFRWLSQ

SAR1A

181

Q9NR31
KQAIEGVGNLRLGYW

SUPT5H

236

O00267
EGWFLVQQLRYILGK

PEX12

171

O00623
WFRGVGPGRELIYNQ

SIRPG

66

Q9P1W8
QWFRGAGPGRELIYN

SIRPB1

66

Q5TFQ8
KGRVPRQGWLYLTVN

TBC1D9B

166

Q66K14
VLKALQDGRAYGSPW

CNOT1

1691

A5YKK6
IWYRAKVIGLPGHQE

RNF17

741

Q9BXT8
DIYQQEGTRGLWRGV

SLC25A14

186

O95258
FRNGGGPAYQLREWK

PLEKHA6

396

Q9Y2H5
NWYGCVEGQQPIVRK

USP4

106

Q13107
VLGTVKWFNVRNGYG

YBX3

91

P16989
NFKSWRGRQVIGPFR

SMC1B

11

Q8NDV3
EVNGKRVRGRQYPWG

SEPTIN7

256

Q16181
KVVSRGGNPWAAVLY

SLC12A9

386

Q9BXP2
RYEFGIFNQKIVNGW

PYGB

161

P11216
PDILNAIKRVGYWSG

VIT

556

Q6UXI7
VLDNRYGLKRWQIGE

SCAI

111

Q8N9R8
WGAGIKYPQRVSAQQ

PIGN

286

O95427
WFGVRKGFPNLGYIQ

PIEZO1

916

Q92508
GLNNGRIKIWDVYTG

WSB1

146

Q9Y6I7
SIINGNWAIDRPGKY

THSD4

461

Q6ZMP0
SIVPVRRGYWGNKIG

RPS2

161

P15880
VHGEGLRWYAGLQKP

TSPO

26

P30536
GYLHWVNDKGTILPR

LPIN2

746

Q92539
GIAIAVEYFWKLGNR

N4BP1

641

O75113
GIYGRLFVWIVDKIN

MYO7A

401

Q13402
GYGIAIQKDSGWKRQ

GRIN2B

761

Q13224
YDGNWFVGRKGVNLK

NECTIN3

276

Q9NQS3