Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionreceptor ligand activity

IL11 NPPC WNT2B GAS6 CXCL16 CXCL1 CXCL2 CXCL3 IL27 SEMA4C VEGFB

5.91e-065477511GO:0048018
GeneOntologyMolecularFunctionsignaling receptor activator activity

IL11 NPPC WNT2B GAS6 CXCL16 CXCL1 CXCL2 CXCL3 IL27 SEMA4C VEGFB

6.67e-065547511GO:0030546
GeneOntologyMolecularFunctionsignaling receptor regulator activity

IL11 NPPC WNT2B GAS6 CXCL16 CXCL1 CXCL2 CXCL3 IL27 SEMA4C VEGFB

1.80e-056167511GO:0030545
GeneOntologyMolecularFunctionCXCR chemokine receptor binding

CXCL1 CXCL2 CXCL3

3.99e-0518753GO:0045236
GeneOntologyMolecularFunctionchemokine activity

CXCL16 CXCL1 CXCL2 CXCL3

4.01e-0551754GO:0008009
GeneOntologyMolecularFunctioninsulin-like growth factor receptor activity

IGF2R CRIM1

4.17e-053752GO:0005010
GeneOntologyMolecularFunctioncytokine activity

IL11 WNT2B CXCL16 CXCL1 CXCL2 CXCL3 IL27

4.26e-05250757GO:0005125
GeneOntologyMolecularFunctioncytoskeleton-nuclear membrane anchor activity

SYNE1 SYNE2

1.38e-045752GO:0140444
GeneOntologyMolecularFunctionmolecular function activator activity

MMP25 IL11 NPPC TIMP2 WNT2B GAS6 CXCL16 CXCL1 CXCL2 CXCL3 TBC1D17 IL27 SEMA4C VEGFB

1.76e-0412337514GO:0140677
GeneOntologyMolecularFunctioncytokine receptor binding

IL11 CXCL16 CXCL1 CXCL2 CXCL3 IL27 VEGFB

2.14e-04324757GO:0005126
GeneOntologyMolecularFunctionchemokine receptor binding

CXCL16 CXCL1 CXCL2 CXCL3

2.45e-0481754GO:0042379
GeneOntologyMolecularFunctionG protein-coupled receptor binding

WNT2B CTHRC1 CXCL16 NPW CXCL1 CXCL2 CXCL3

2.72e-04337757GO:0001664
GeneOntologyMolecularFunctionguanylate cyclase activity

NPR1 GUCY2D

6.14e-0410752GO:0004383
GeneOntologyMolecularFunctionintracellularly cAMP-activated cation channel activity

HCN4 HCN1

6.14e-0410752GO:0005222
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

GABRD KCNU1 HCN4 HCN1 CHRNA3

7.99e-04193755GO:0015276
GeneOntologyMolecularFunctionligand-gated channel activity

GABRD KCNU1 HCN4 HCN1 CHRNA3

8.76e-04197755GO:0022834
GeneOntologyMolecularFunctionintracellularly cyclic nucleotide-activated monoatomic cation channel activity

HCN4 HCN1

1.06e-0313752GO:0005221
GeneOntologyMolecularFunctioncyclic nucleotide-activated monoatomic ion channel activity

HCN4 HCN1

1.06e-0313752GO:0043855
GeneOntologyMolecularFunctionpotassium channel activity

KCNU1 HCN4 HCN1 TMEM175

1.38e-03128754GO:0005267
GeneOntologyMolecularFunctionmonoatomic ion channel activity

GABRD TPTE KCNU1 HCN4 HCN1 TMEM175 CHRNA3

1.67e-03459757GO:0005216
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

KCNU1 HCN4 HCN1 CHRNA3

1.91e-03140754GO:0099094
GeneOntologyMolecularFunctionadenylate cyclase activity

NPR1 GUCY2D

2.05e-0318752GO:0004016
GeneOntologyMolecularFunctionintramolecular oxidoreductase activity, transposing S-S bonds

TXNDC5 PDIA2

3.06e-0322752GO:0016864
GeneOntologyMolecularFunctionprotein disulfide isomerase activity

TXNDC5 PDIA2

3.06e-0322752GO:0003756
GeneOntologyMolecularFunctionchannel activity

GABRD TPTE KCNU1 HCN4 HCN1 TMEM175 CHRNA3

3.54e-03525757GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

GABRD TPTE KCNU1 HCN4 HCN1 TMEM175 CHRNA3

3.58e-03526757GO:0022803
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

KCNU1 HCN4 HCN1 TMEM175

3.62e-03167754GO:0015079
GeneOntologyMolecularFunctioncyclase activity

NPR1 GUCY2D

3.64e-0324752GO:0009975
GeneOntologyMolecularFunctionphosphorus-oxygen lyase activity

NPR1 GUCY2D

3.95e-0325752GO:0016849
GeneOntologyMolecularFunctioncAMP binding

HCN4 HCN1

3.95e-0325752GO:0030552
GeneOntologyMolecularFunctioncargo receptor activity

AMN CXCL16 TMED3

4.03e-0385753GO:0038024
GeneOntologyMolecularFunctiongrowth factor activity

IL11 CXCL1 CXCL2 VEGFB

4.10e-03173754GO:0008083
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

HCN4 HCN1

4.27e-0326752GO:0005248
GeneOntologyBiologicalProcesscyclic nucleotide biosynthetic process

NPPC NPR1 GUCY2D PTH2

1.43e-0623764GO:0009190
GeneOntologyBiologicalProcesscGMP biosynthetic process

NPPC NPR1 GUCY2D

1.03e-0512763GO:0006182
GeneOntologyBiologicalProcessreceptor guanylyl cyclase signaling pathway

NPPC NPR1 GUCY2D

1.03e-0512763GO:0007168
GeneOntologyBiologicalProcesscyclic purine nucleotide metabolic process

NPPC NPR1 GUCY2D PTH2

2.07e-0544764GO:0052652
GeneOntologyBiologicalProcesscyclic nucleotide metabolic process

NPPC NPR1 GUCY2D PTH2

2.26e-0545764GO:0009187
GeneOntologyBiologicalProcesscGMP metabolic process

NPPC NPR1 GUCY2D

4.46e-0519763GO:0046068
GeneOntologyBiologicalProcessregulation of cilium assembly

SYNE1 SYNE2 FUZ TBC1D17 HTT

4.93e-05108765GO:1902017
GeneOntologyCellularComponentsecretory granule

MMP25 NPPC IGF2R TXNDC5 TIMP2 TCP11 LILRB2 DPEP3 PRDX4 GAS6 LAMP1 CXCL1 VEGFB

5.88e-0510147513GO:0030141
GeneOntologyCellularComponentHCN channel complex

HCN4 HCN1

7.59e-054752GO:0098855
GeneOntologyCellularComponentpostsynaptic membrane

GABRD SYNE1 HCN1 ADGRB1 C1QC CHRNA3 SHISA8 SEMA4C

1.01e-04405758GO:0045211
GeneOntologyCellularComponentsecretory vesicle

MMP25 NPPC IGF2R TXNDC5 TIMP2 TCP11 LILRB2 DPEP3 PRDX4 GAS6 LAMP1 CXCL1 SEMA4C VEGFB

1.22e-0412467514GO:0099503
GeneOntologyCellularComponentendoplasmic reticulum lumen

FKBP10 POGLUT3 TXNDC5 NUCB1 GAS6 PDIA2 IL27

1.88e-04332757GO:0005788
GeneOntologyCellularComponentsynaptic membrane

GABRD SYNE1 HCN1 ADGRB1 C1QC CHRNA3 HTT SHISA8 SEMA4C

2.34e-04583759GO:0097060
GeneOntologyCellularComponentnuclear outer membrane

SYNE1 GUCY2D SYNE2

3.98e-0440753GO:0005640
GeneOntologyCellularComponentmicrotubule organizing center attachment site

SYNE1 SYNE2

6.84e-0411752GO:0034992
GeneOntologyCellularComponentmeiotic nuclear membrane microtubule tethering complex

SYNE1 SYNE2

6.84e-0411752GO:0034993
GeneOntologyCellularComponentnuclear membrane protein complex

SYNE1 SYNE2

6.84e-0411752GO:0106083
GeneOntologyCellularComponentnuclear membrane microtubule tethering complex

SYNE1 SYNE2

6.84e-0411752GO:0106094
GeneOntologyCellularComponentsecretory granule lumen

TXNDC5 TIMP2 PRDX4 GAS6 CXCL1 VEGFB

1.10e-03325756GO:0034774
GeneOntologyCellularComponentcytoplasmic vesicle lumen

TXNDC5 TIMP2 PRDX4 GAS6 CXCL1 VEGFB

1.19e-03330756GO:0060205
GeneOntologyCellularComponentvesicle lumen

TXNDC5 TIMP2 PRDX4 GAS6 CXCL1 VEGFB

1.23e-03332756GO:0031983
GeneOntologyCellularComponentmonoatomic ion channel complex

GABRD KCNU1 HCN4 HCN1 CHRNA3 SHISA8

2.37e-03378756GO:0034702
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

TPTE LPCAT2 SYNE1 GUCY2D SYNE2 SSR1 HSD11B2 IHH PTGFRN EIF2AK3 MYMX TMED3

2.58e-0313277512GO:0042175
GeneOntologyCellularComponenttertiary granule

TIMP2 LILRB2 LAMP1 CXCL1

2.88e-03164754GO:0070820
GeneOntologyCellularComponentGolgi stack

LPCAT2 NUCB1 TMEM115 TMED3

3.35e-03171754GO:0005795
GeneOntologyCellularComponentdendrite

GABRD HCN4 SYNE1 HCN1 ADGRB1 LAMP1 CHRNA3 HTT SHISA8

3.52e-03858759GO:0030425
GeneOntologyCellularComponentdendritic tree

GABRD HCN4 SYNE1 HCN1 ADGRB1 LAMP1 CHRNA3 HTT SHISA8

3.58e-03860759GO:0097447
GeneOntologyCellularComponentsomatodendritic compartment

GABRD HCN4 TIMP2 SYNE1 HCN1 ADGRB1 LMTK2 LAMP1 CHRNA3 HTT SHISA8

4.23e-0312287511GO:0036477
DomainChemokine_CXC

CXCL16 CXCL1 CXCL2 CXCL3

4.21e-0716754IPR001089
DomainSMALL_CYTOKINES_CXC

CXCL16 CXCL1 CXCL2 CXCL3

5.49e-0717754PS00471
DomainChemokine_CXC_CS

CXCL1 CXCL2 CXCL3

1.73e-0513753IPR018048
DomainCXC_Chemokine_domain

CXCL1 CXCL2 CXCL3

2.19e-0514753IPR033899
DomainER_TARGET

FKBP10 POGLUT3 TXNDC5 PDIA2

3.75e-0547754PS00014
DomainKASH

SYNE1 SYNE2

9.50e-054752PF10541
DomainKASH

SYNE1 SYNE2

9.50e-054752IPR012315
DomainIon_trans_N

HCN4 HCN1

9.50e-054752PF08412
DomainIon_trans_N

HCN4 HCN1

9.50e-054752IPR013621
DomainKASH

SYNE1 SYNE2

9.50e-054752PS51049
DomainKASH

SYNE1 SYNE2

9.50e-054752SM01249
DomainDisulphide_isomerase

TXNDC5 PDIA2

4.39e-048752IPR005788
DomainThioredoxin_domain

TXNDC5 PRDX4 PDIA2

5.94e-0441753IPR013766
DomainSCY

CXCL1 CXCL2 CXCL3

6.38e-0442753SM00199
DomainTHIOREDOXIN_2

TXNDC5 PRDX4 PDIA2

6.84e-0443753PS51352
DomainChemokine_IL8-like_dom

CXCL1 CXCL2 CXCL3

7.32e-0444753IPR001811
DomainIL8

CXCL1 CXCL2 CXCL3

7.32e-0444753PF00048
DomainLaminin_G_1

GAS6 SHBG

8.55e-0411752PF00054
DomainIon_trans_dom

TPTE KCNU1 HCN4 HCN1

1.15e-03114754IPR005821
DomainIon_trans

TPTE KCNU1 HCN4 HCN1

1.15e-03114754PF00520
DomainThioredoxin

TXNDC5 PDIA2

1.21e-0313752IPR005746
DomainK_chnl_volt-dep_EAG/ELK/ERG

HCN4 HCN1

1.40e-0314752IPR003938
DomaincNMP-bd_CS

HCN4 HCN1

1.84e-0316752IPR018488
DomainA/G_cyclase_CS

NPR1 GUCY2D

2.08e-0317752IPR018297
DomainThioredoxin_CS

TXNDC5 PDIA2

2.08e-0317752IPR017937
DomainNucleotide_cyclase

NPR1 GUCY2D

2.34e-0318752IPR029787
Domain-

NPR1 GUCY2D

2.34e-03187523.30.70.1230
DomainGUANYLATE_CYCLASE_1

NPR1 GUCY2D

2.60e-0319752PS00452
DomainGuanylate_cyc

NPR1 GUCY2D

2.60e-0319752PF00211
DomainGUANYLATE_CYCLASE_2

NPR1 GUCY2D

2.60e-0319752PS50125
DomainA/G_cyclase

NPR1 GUCY2D

2.60e-0319752IPR001054
DomainCYCc

NPR1 GUCY2D

2.60e-0319752SM00044
DomainActinin_actin-bd_CS

SYNE1 SYNE2

3.81e-0323752IPR001589
DomainPentatricopeptide_repeat

XAB2 HTT

3.81e-0323752IPR002885
DomainSpectrin

SYNE1 SYNE2

3.81e-0323752PF00435
DomainACTININ_2

SYNE1 SYNE2

3.81e-0323752PS00020
DomainACTININ_1

SYNE1 SYNE2

3.81e-0323752PS00019
PathwayWP_OVERVIEW_OF_PROINFLAMMATORY_AND_PROFIBROTIC_MEDIATORS

IL11 CXCL16 CXCL1 CXCL2 CXCL3 IL27

2.12e-05127636M42533
PathwayWP_CYTOKINES_AND_INFLAMMATORY_RESPONSE

IL11 CXCL1 CXCL2 CXCL3

2.65e-0539634MM15914
PathwayWP_RETT_SYNDROME

GABRD SYNE2 XAB2 HTT

6.08e-0548634M39759
PathwayREACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES

CXCL16 CXCL1 CXCL2 CXCL3

1.20e-0457634M625
PathwayREACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES

CXCL16 CXCL1 CXCL2 CXCL3

1.28e-0458634MM14978
PathwayREACTOME_GPCR_LIGAND_BINDING

GIPR WNT2B PTH2 CXCL16 NPW IHH CXCL1 CXCL2 CXCL3

2.01e-04463639M507
PathwayWP_CYTOKINES_AND_INFLAMMATORY_RESPONSE

IL11 CXCL1 CXCL2

2.06e-0426633M39711
PathwayREACTOME_PHYSIOLOGICAL_FACTORS

NPPC NPR1

4.07e-047632MM15201
PathwayREACTOME_NEUTROPHIL_DEGRANULATION

MMP25 IGF2R TXNDC5 TIMP2 LILRB2 PRDX4 LAMP1 CXCL2 CD300C

4.17e-04511639MM15330
PathwayREACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS

GIPR WNT2B PTH2 IHH

8.18e-0494634M797
PathwayWP_CYTOKINECYTOKINE_RECEPTOR_INTERACTION

IL11 CXCL16 CXCL1 CXCL2 CXCL3 IL27

9.28e-04254636M48344
Pubmed

FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.

FKBP10 POGLUT3 IGF2R TXNDC5 BRI3BP LPCAT2 PRDX4 SYNE2 TMEM115 SSR1 EIF2AK3 SEMA4C

5.11e-10468771231056421
Pubmed

Oxygen radical-dependent expression of CXC chemokines regulate ischemia/reperfusion-induced leukocyte adhesion in the mouse colon.

CXCL1 CXCL2 CXCL3

1.04e-08377314583342
Pubmed

Effects of nanoparticulate saponin-platinum conjugates on 2,4-dinitrofluorobenzene-induced macrophage inflammatory protein-2 gene expression via reactive oxygen species production in RAW 264.7 cells.

CXCL1 CXCL2 CXCL3

1.04e-08377319470246
Pubmed

Brain border-derived CXCL2+ neutrophils drive NET formation and impair vascular reperfusion following ischemic stroke.

CXCL1 CXCL2 CXCL3

1.04e-08377339135337
Pubmed

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19.

CXCL1 CXCL2 CXCL3

1.04e-08377332416070
Pubmed

Myeloperoxidase deficiency induces MIP-2 production via ERK activation in zymosan-stimulated mouse neutrophils.

CXCL1 CXCL2 CXCL3

1.04e-08377323438680
Pubmed

Macrophage inflammatory protein-2 contributes to liver resection-induced acceleration of hepatic metastatic tumor growth.

CXCL1 CXCL2 CXCL3

1.04e-08377316521212
Pubmed

CXCL2 mediates lipopolysaccharide-induced osteoclastogenesis in RANKL-primed precursors.

CXCL1 CXCL2 CXCL3

1.04e-08377321507677
Pubmed

Regulation of macrophage inflammatory protein-2 gene expression in response to 2,4-dinitrofluorobenzene in RAW 264.7 cells.

CXCL1 CXCL2 CXCL3

1.04e-08377318452653
Pubmed

Suppression of CXCL2 upregulation underlies the therapeutic effect of the retinoid Am80 on intracerebral hemorrhage in mice.

CXCL1 CXCL2 CXCL3

1.04e-08377324659080
Pubmed

The coronavirus spike protein induces endoplasmic reticulum stress and upregulation of intracellular chemokine mRNA concentrations.

CXCL1 CXCL2 CXCL3

1.04e-08377317670839
Pubmed

Postnatal acquisition of endotoxin tolerance in intestinal epithelial cells.

CXCL1 CXCL2 CXCL3

1.04e-08377316606665
Pubmed

Mycobacterium tuberculosis-triggered Hippo pathway orchestrates CXCL1/2 expression to modulate host immune responses.

CXCL1 CXCL2 CXCL3

1.04e-08377327883091
Pubmed

Activation of the nuclear factor-κB pathway during postnatal lung inflammation preserves alveolarization by suppressing macrophage inflammatory protein-2.

CXCL1 CXCL2 CXCL3

1.04e-08377326163511
Pubmed

CXCL1 mediates obesity-associated adipose stromal cell trafficking and function in the tumour microenvironment.

CXCL1 CXCL2 CXCL3

1.04e-08377327241286
Pubmed

Neutrophils play an important role in host resistance to respiratory infection with Acinetobacter baumannii in mice.

CXCL1 CXCL2 CXCL3

1.04e-08377317908807
Pubmed

CXCL2 attenuates osteoblast differentiation by inhibiting the ERK1/2 signaling pathway.

CXCL1 CXCL2 CXCL3

1.04e-08377331292171
Pubmed

Cis-acting lnc-Cxcl2 restrains neutrophil-mediated lung inflammation by inhibiting epithelial cell CXCL2 expression in virus infection.

CXCL1 CXCL2 CXCL3

1.04e-08377334607953
Pubmed

Nucleotide sequence of the human melanoma growth stimulatory activity (MGSA) gene.

CXCL1 CXCL2 CXCL3

1.04e-0837732129556
Pubmed

Molecular cloning and biophysical characterization of CXCL3 chemokine.

CXCL1 CXCL2 CXCL3

1.04e-08377328928065
Pubmed

Ectopic lymphoid tissue formation in the lungs of mice infected with Chlamydia pneumoniae is associated with epithelial macrophage inflammatory protein-2/CXCL2 expression.

CXCL1 CXCL2 CXCL3

1.04e-08377320840653
Pubmed

Early infiltrating NKT lymphocytes attenuate bone regeneration through secretion of CXCL2.

CXCL1 CXCL2 CXCL3

1.04e-08377338758783
Pubmed

Neutrophil chemoattractant genes KC and MIP-2 are expressed in different cell populations at sites of surgical injury.

CXCL1 CXCL2 CXCL3

1.04e-08377314704366
Pubmed

Pyrrolidine dithiocarbamate-induced macrophage inflammatory protein-2 gene expression is NF-kappaB-independent but c-Jun-dependent in macrophage cell line RAW 264.7.

CXCL1 CXCL2 CXCL3

1.04e-08377315829306
Pubmed

Liver resection-associated macrophage inflammatory protein-2 stimulates engraftment but not growth of colorectal metastasis at extrahepatic sites.

CXCL1 CXCL2 CXCL3

1.04e-08377317561115
Pubmed

Distinct temporal patterns of macrophage-inflammatory protein-2 and KC chemokine gene expression in surgical injury.

CXCL1 CXCL2 CXCL3

1.04e-08377311907123
Pubmed

Nitric oxide stimulates macrophage inflammatory protein-2 expression in sepsis.

CXCL1 CXCL2 CXCL3

1.04e-08377312165537
Pubmed

Transcriptional regulation of CXC-ELR chemokines KC and MIP-2 in mouse pancreatic acini.

CXCL1 CXCL2 CXCL3

1.04e-08377320671197
Pubmed

Theiler's virus induces the MIP-2 chemokine (CXCL2) in astrocytes from genetically susceptible but not from resistant mouse strains.

CXCL1 CXCL2 CXCL3

1.04e-08377316684516
Pubmed

Macrophage inflammatory protein-2 and vascular endothelial growth factor regulate corneal neovascularization induced by infection with Pseudomonas aeruginosa in mice.

CXCL1 CXCL2 CXCL3

1.04e-08377312121220
Pubmed

Upregulation of MIP-2 (CXCL2) expression by 15-deoxy-Delta(12,14)-prostaglandin J(2) in mouse peritoneal macrophages.

CXCL1 CXCL2 CXCL3

1.04e-08377317130903
Pubmed

Identification of three related human GRO genes encoding cytokine functions.

CXCL1 CXCL2 CXCL3

1.04e-0837732217207
Pubmed

Macrophages are targeted by rotavirus in experimental biliary atresia and induce neutrophil chemotaxis by Mip2/Cxcl2.

CXCL1 CXCL2 CXCL3

1.04e-08377320234283
Pubmed

CXCL3 positively regulates adipogenic differentiation.

CXCL1 CXCL2 CXCL3

1.04e-08377327512010
Pubmed

Swine Influenza Virus PA and Neuraminidase Gene Reassortment into Human H1N1 Influenza Virus Is Associated with an Altered Pathogenic Phenotype Linked to Increased MIP-2 Expression.

CXCL1 CXCL2 CXCL3

1.04e-08377325762737
Pubmed

Cloning and characterization of cDNAs for murine macrophage inflammatory protein 2 and its human homologues.

CXCL1 CXCL2 CXCL3

1.04e-0837732201751
Pubmed

Critical role of CXC chemokines in endotoxemic liver injury in mice.

CXCL1 CXCL2 CXCL3

1.04e-08377314673016
Pubmed

A suppressive role of nitric oxide in MIP-2 production by macrophages upon coculturing with apoptotic cells.

CXCL1 CXCL2 CXCL3

1.04e-08377316855064
Pubmed

Macrophage inflammatory protein-2, neutrophil recruitment and bacterial persistence in an experimental mouse model of urinary tract infection.

CXCL1 CXCL2 CXCL3

1.04e-08377315555540
Pubmed

Dysregulated macrophage-inflammatory protein-2 expression drives illness in bacterial superinfection of influenza.

CXCL1 CXCL2 CXCL3

1.04e-08377320065113
Pubmed

2,4-Dinitrofluorobenzene modifies cellular proteins and induces macrophage inflammatory protein-2 gene expression via reactive oxygen species production in RAW 264.7 cells.

CXCL1 CXCL2 CXCL3

1.04e-08377319330623
Pubmed

Identification and characterization of macrophage inflammatory protein 2.

CXCL1 CXCL2 CXCL3

1.04e-0837732643119
Pubmed

Immature dendritic cells reduce proinflammatory cytokine production by a coculture of macrophages and apoptotic cells in a cell-to-cell contact-dependent manner.

CXCL1 CXCL2 CXCL3

1.04e-08377314761936
Pubmed

Macrophage inflammatory protein 2 inhibits beta-amyloid peptide (1-42)-mediated hippocampal neuronal apoptosis through activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling pathways.

CXCL1 CXCL2 CXCL3

1.04e-08377315608143
Pubmed

Macrophagic Extracellular Vesicle CXCL2 Recruits and Activates the Neutrophil CXCR2/PKC/NOX4 Axis in Sepsis.

CXCL1 CXCL2 CXCL3

1.04e-08377334507947
Pubmed

Solution structure of murine macrophage inflammatory protein-2.

CXCL1 CXCL2 CXCL3

1.04e-0837739622482
Pubmed

The chemokine, macrophage inflammatory protein-2γ, reduces the expression of glutamate transporter-1 on astrocytes and increases neuronal sensitivity to glutamate excitotoxicity.

CXCL1 CXCL2 CXCL3

1.04e-08377323234294
Pubmed

Mitogenic properties of endogenous and pharmacological doses of macrophage inflammatory protein-2 after 70% hepatectomy in the mouse.

CXCL1 CXCL2 CXCL3

1.04e-08377312875976
Pubmed

Peripheral blood stem cell mobilization: the CXCR2 ligand GRObeta rapidly mobilizes hematopoietic stem cells with enhanced engraftment properties.

CXCL1 CXCL2 CXCL3

1.04e-08377316863907
Pubmed

Molecular cloning of the guinea pig GRO gene and its rapid expression in the tissues of lipopolysaccharide-injected guinea pigs.

CXCL1 CXCL2 CXCL3

1.04e-08377310394101
Pubmed

An NF-kappa B-like transcription factor mediates IL-1/TNF-alpha induction of gro in human fibroblasts.

CXCL1 CXCL2 CXCL3

1.04e-0837731906501
Pubmed

Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.

GIPR PTH2 CXCL16 NPW CXCL1 CXCL2 CXCL3 GNRHR2

1.56e-0820077818240029
Pubmed

Tumor-associated macrophages mediate gastrointestinal stromal tumor cell metastasis through CXCL2/CXCR2.

CXCL1 CXCL2 CXCL3

4.17e-08477336577281
Pubmed

Epigenetic augmentation of the macrophage inflammatory protein 2/C-X-C chemokine receptor type 2 axis through histone H3 acetylation in injured peripheral nerves elicits neuropathic pain.

CXCL1 CXCL2 CXCL3

4.17e-08477322135382
Pubmed

PXR Functionally Interacts with NF-κB and AP-1 to Downregulate the Inflammation-Induced Expression of Chemokine CXCL2 in Mice.

CXCL1 CXCL2 CXCL3

4.17e-08477333076328
Pubmed

TRPM2 Exacerbates Central Nervous System Inflammation in Experimental Autoimmune Encephalomyelitis by Increasing Production of CXCL2 Chemokines.

CXCL1 CXCL2 CXCL3

4.17e-08477330201769
Pubmed

Involvement of KC, MIP-2, and MCP-1 in leukocyte infiltration following injection of necrotic cells into the peritoneal cavity.

CXCL1 CXCL2 CXCL3

4.17e-08477317662241
Pubmed

CXC chemokine ligand 2 induced by receptor activator of NF-kappa B ligand enhances osteoclastogenesis.

CXCL1 CXCL2 CXCL3

4.17e-08477320357249
Pubmed

Identification of the most active interleukin-32 isoform.

CXCL1 CXCL2 CXCL3

4.17e-08477318771438
Pubmed

Daidzein suppresses pro-inflammatory chemokine Cxcl2 transcription in TNF-α-stimulated murine lung epithelial cells via depressing PARP-1 activity.

CXCL1 CXCL2 CXCL3

4.17e-08477324632845
Pubmed

Microglial lnc-U90926 facilitates neutrophil infiltration in ischemic stroke via MDH2/CXCL2 axis.

CXCL1 CXCL2 CXCL3

4.17e-08477333895326
Pubmed

Neutrophil recruitment by chemokines Cxcl1/KC and Cxcl2/MIP2: Role of Cxcr2 activation and glycosaminoglycan interactions.

CXCL1 CXCL2 CXCL3

4.17e-08477332881070
Pubmed

Differential binding of chemokines CXCL1, CXCL2 and CCL2 to mouse glomerular endothelial cells reveals specificity for distinct heparan sulfate domains.

CXCL1 CXCL2 CXCL3

4.17e-08477330248108
Pubmed

Extracellular ATP-stimulated macrophages produce macrophage inflammatory protein-2 which is important for neutrophil migration.

CXCL1 CXCL2 CXCL3

4.17e-08477322564028
Pubmed

The chemokine and chemokine receptor superfamilies and their molecular evolution.

CXCL1 CXCL2 CXCL3

4.17e-08477317201934
Pubmed

The calcium-conducting ion channel transient receptor potential canonical 6 is involved in macrophage inflammatory protein-2-induced migration of mouse neutrophils.

CXCL1 CXCL2 CXCL3

4.17e-08477318983454
Pubmed

The Role of C-X-C Chemokines in Staphylococcus aureus Endophthalmitis.

CXCL1 CXCL2 CXCL3

4.17e-08477336867134
Pubmed

High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras.

CXCL1 CXCL2 CXCL3

4.17e-08477316618742
Pubmed

Small heterodimer partner negatively regulates C-X-C motif chemokine ligand 2 in hepatocytes during liver inflammation.

CXCL1 CXCL2 CXCL3

4.17e-08477330323351
Pubmed

Induction of TNF-alfa and CXCL-2 mRNAs in different organs of mice infected with pathogenic Leptospira.

CXCL1 CXCL2 CXCL3

4.17e-08477322342618
Pubmed

The Th17-ELR+ CXC chemokine pathway is essential for the development of central nervous system autoimmune disease.

CXCL1 CXCL2 CXCL3

4.17e-08477318347102
Pubmed

Rho-kinase signalling regulates CXC chemokine formation and leukocyte recruitment in colonic ischemia-reperfusion.

CXCL1 CXCL2 CXCL3

4.17e-08477320593289
Pubmed

Necrotic foci, elevated chemokines and infiltrating neutrophils in the liver of glycogen storage disease type Ia.

CXCL1 CXCL2 CXCL3

4.17e-08477318191274
Pubmed

Toll-like receptor 4 ligation on intrinsic renal cells contributes to the induction of antibody-mediated glomerulonephritis via CXCL1 and CXCL2.

CXCL1 CXCL2 CXCL3

4.17e-08477317460147
Pubmed

The murine interleukin 8 type B receptor homologue and its ligands. Expression and biological characterization.

CXCL1 CXCL2 CXCL3

4.17e-0847737961909
Pubmed

IP-10 protects while MIP-2 promotes experimental anesthetic hapten - induced hepatitis.

CXCL1 CXCL2 CXCL3

4.17e-08477319131211
Pubmed

The interleukin-1β/CXCL1/2/neutrophil axis mediates host protection against group B streptococcal infection.

CXCL1 CXCL2 CXCL3

4.17e-08477325114117
Pubmed

TRPM2 modulates neutrophil attraction to murine tumor cells by regulating CXCL2 expression.

CXCL1 CXCL2 CXCL3

4.17e-08477330251149
Pubmed

CXCL1 and CXCL2 Regulate NLRP3 Inflammasome Activation via G-Protein-Coupled Receptor CXCR2.

CXCL1 CXCL2 CXCL3

4.17e-08477328739876
Pubmed

TREM2 promotes macrophage polarization from M1 to M2 and suppresses osteoarthritis through the NF-κB/CXCL3 axis.

CXCL1 CXCL2 CXCL3

4.17e-08477338617547
Pubmed

Commensal bacteria-dependent select expression of CXCL2 contributes to periodontal tissue homeostasis.

CXCL1 CXCL2 CXCL3

4.17e-08477323433011
Pubmed

The K1 serotype capsular polysaccharide of Porphyromonas gingivalis elicits chemokine production from murine macrophages that facilitates cell migration.

CXCL1 CXCL2 CXCL3

4.17e-08477316940143
Pubmed

CXCL12 promotes the stabilization of atherosclerotic lesions mediated by smooth muscle progenitor cells in Apoe-deficient mice.

CXCL1 CXCL2 CXCL3

4.17e-08477323393393
Pubmed

The coordinated action of G-CSF and ELR + CXC chemokines in neutrophil mobilization during acute inflammation.

CXCL1 CXCL2 CXCL3

4.17e-08477317928531
Pubmed

Fpr2/CXCL1/2 Controls Rapid Neutrophil Infiltration to Inhibit Streptococcus agalactiae Infection.

CXCL1 CXCL2 CXCL3

4.17e-08477334899755
Pubmed

C-X-C Chemokines Influence Intraocular Inflammation During Bacillus Endophthalmitis.

CXCL1 CXCL2 CXCL3

4.17e-08477334784411
Pubmed

The role of CXCR2 in systemic neovascularization of the mouse lung.

CXCL1 CXCL2 CXCL3

4.17e-08477317556491
Pubmed

A model of GAG/MIP-2/CXCR2 interfaces and its functional effects.

CXCL1 CXCL2 CXCL3

4.17e-08477322686371
Pubmed

CXCR2 ligands and G-CSF mediate PKCalpha-induced intraepidermal inflammation.

CXCL1 CXCL2 CXCL3

4.17e-08477316964312
Pubmed

Macrophage Inflammatory Protein-2 in High Mobility Group Box 1 Secretion of Macrophage Cells Exposed to Lipopolysaccharide.

CXCL1 CXCL2 CXCL3

4.17e-08477328662496
Pubmed

Pneumocystis carinii activates the NF-kappaB signaling pathway in alveolar epithelial cells.

CXCL1 CXCL2 CXCL3

4.17e-08477315845480
Pubmed

Distinct Compartmentalization of the Chemokines CXCL1 and CXCL2 and the Atypical Receptor ACKR1 Determine Discrete Stages of Neutrophil Diapedesis.

CXCL1 CXCL2 CXCL3

4.17e-08477330446388
Pubmed

P2X7 receptor activation induces CXCL2 production in microglia through NFAT and PKC/MAPK pathways.

CXCL1 CXCL2 CXCL3

4.17e-08477320477948
Pubmed

High tidal volume upregulates intrapulmonary cytokines in an in vivo mouse model of ventilator-induced lung injury.

CXCL1 CXCL2 CXCL3

4.17e-08477312807894
Pubmed

Steroid Receptor Coactivator 3 Contributes to Host Defense against Enteric Bacteria by Recruiting Neutrophils via Upregulation of CXCL2 Expression.

CXCL1 CXCL2 CXCL3

4.17e-08477328053238
Pubmed

High-cholesterol diet facilitates Anaplasma phagocytophilum infection and up-regulates macrophage inflammatory protein-2 and CXCR2 expression in apolipoprotein E-deficient mice.

CXCL1 CXCL2 CXCL3

4.17e-08477317436230
Pubmed

Syndecan-1 in the mouse parietal peritoneum microcirculation in inflammation.

CXCL1 CXCL2 CXCL3

4.17e-08477325184228
Pubmed

TcpC secreting uropathogenic E. coli promoted kidney cells to secrete MIP-2 via p38 MAPK pathway.

CXCL1 CXCL2 CXCL3

4.17e-08477328765918
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

FKBP10 NPR1 IGF2R TXNDC5 CRIM1 BRI3BP LPCAT2 PRDX4 NUCB1 LAMP1 SSR1 PTGFRN EIF2AK3 HTT TMED3

5.15e-081201771535696571
Pubmed

Developmental expression of two CXC chemokines, MIP-2 and KC, and their receptors.

CXCL1 CXCL2 CXCL3

1.04e-07577311444905
InteractionCXCL3 interactions

TIMP2 CXCL1 CXCL2 CXCL3

1.63e-0714744int:CXCL3
InteractionFBXO2 interactions

POGLUT3 IGF2R SUSD1 SYNE2 GAS6 CTHRC1 ADAM33 PTGFRN HTT SEMA4C

2.50e-064117410int:FBXO2
InteractionSEC61B interactions

FKBP10 POGLUT3 IGF2R TXNDC5 BRI3BP LPCAT2 SYNE1 PRDX4 SYNE2 NUCB1 SSR1 EIF2AK3 SEMA4C

3.68e-067637413int:SEC61B
InteractionSYNE3 interactions

FKBP10 POGLUT3 IGF2R TXNDC5 BRI3BP PRDX4 SYNE2 NUCB1 SSR1 EIF2AK3

4.97e-064447410int:SYNE3
InteractionLRRC59 interactions

FKBP10 POGLUT3 IGF2R TXNDC5 BRI3BP SYNE1 PRDX4 SYNE2 NUCB1 LAMP1 XPC SSR1 EIF2AK3

1.10e-058457413int:LRRC59
InteractionCALR3 interactions

FKBP10 POGLUT3 TXNDC5 BRI3BP PRDX4 NUCB1

1.38e-05142746int:CALR3
InteractionSEC62 interactions

IGF2R TXNDC5 BRI3BP LPCAT2 SYNE1 PRDX4 SYNE2 SSR1 EIF2AK3 SEMA4C

1.55e-055067410int:SEC62
InteractionRAB3B interactions

IGF2R TIMP2 SYNE2 ADGRB1 LAMP1 EIF2AK3 HTT SEMA4C

1.79e-05310748int:RAB3B
InteractionVAPA interactions

FKBP10 POGLUT3 TXNDC5 BRI3BP PRDX4 SYNE2 CTHRC1 LAMP1 SSR1 EIF2AK3 HTT

3.90e-056867411int:VAPA
InteractionTMT1A interactions

IGF2R BRI3BP SYNE1 SYNE2 TMEM115 SSR1 EIF2AK3 SEMA4C

5.08e-05359748int:TMT1A
InteractionPDIA4 interactions

FKBP10 POGLUT3 IGF2R TXNDC5 BRI3BP SYNE1 PRDX4 NUCB1 LAMP1

5.28e-05468749int:PDIA4
InteractionCXCR1 interactions

CXCL1 CXCL2 CXCL3

6.03e-0521743int:CXCR1
InteractionDNAJC25 interactions

IGF2R BRI3BP SYNE1 PRDX4 SYNE2 SSR1 EIF2AK3

8.24e-05284747int:DNAJC25
InteractionATP1B4 interactions

SYNE1 GAS6 PTGFRN SEMA4C

1.14e-0468744int:ATP1B4
InteractionCXCL1 interactions

CXCL1 CXCL2 CXCL3

1.16e-0426743int:CXCL1
InteractionOTULINL interactions

IGF2R BRI3BP LPCAT2 SYNE2 TMEM115 SSR1 EIF2AK3 SEMA4C

1.18e-04405748int:OTULINL
InteractionCXCL5 interactions

CXCL1 CXCL2 CXCL3

1.30e-0427743int:CXCL5
InteractionCXCL2 interactions

CXCL1 CXCL2 CXCL3

1.30e-0427743int:CXCL2
InteractionTMEM106B interactions

FKBP10 POGLUT3 TXNDC5 BRI3BP NUCB1 LAMP1 SSR1

1.39e-04309747int:TMEM106B
InteractionDNAJC3 interactions

FKBP10 POGLUT3 TXNDC5 PRDX4 LAMP1 EIF2AK3

1.83e-04226746int:DNAJC3
InteractionTCTN1 interactions

FKBP10 POGLUT3 TXNDC5 BRI3BP PRDX4

2.35e-04151745int:TCTN1
InteractionCCL11 interactions

CXCL1 CXCL2 CXCL3

2.62e-0434743int:CCL11
InteractionRAB4A interactions

IGF2R SYNE1 SYNE2 TMEM115 LMTK2 LAMP1 HTT SEMA4C

2.68e-04457748int:RAB4A
InteractionEPHA10 interactions

FKBP10 POGLUT3 TXNDC5 PRDX4

2.83e-0486744int:EPHA10
InteractionCXCR2 interactions

CXCL1 CXCL2 CXCL3

3.11e-0436743int:CXCR2
Cytoband4q21

CXCL1 CXCL2 CXCL3

5.07e-06207734q21
Cytoband19q13.33

NUCB1 PTH2 FUZ TBC1D17

3.19e-0510677419q13.33
Cytoband6p24.3

TXNDC5 SSR1

6.28e-04227726p24.3
Cytoband16p13.3

MMP25 TELO2 PDIA2 NPW

7.77e-0424477416p13.3
CytobandEnsembl 112 genes in cytogenetic band chr4q13

CXCL1 CXCL2 CXCL3

2.38e-03157773chr4q13
Cytoband13q34

GAS6 LAMP1

3.76e-035477213q34
CytobandEnsembl 112 genes in cytogenetic band chr19q13

IL11 GIPR LILRB2 NUCB1 PTH2 FUZ TBC1D17

3.88e-031192777chr19q13
GeneFamilyEndogenous ligands

IL11 NPPC PTH2 CXCL16 NPW CXCL1 CXCL2 CXCL3 HTT

5.11e-08237579542
GeneFamilyChemokine ligands|Endogenous ligands

CXCL16 CXCL1 CXCL2 CXCL3

1.20e-0545574483
GeneFamilySpectrin repeat containing nuclear envelope family

SYNE1 SYNE2

5.84e-0545721252
GeneFamilyGuanylate cyclase receptors

NPR1 GUCY2D

2.03e-047572343
GeneFamilyCyclic nucleotide gated channels

HCN4 HCN1

4.32e-0410572250
GeneFamilyADAM metallopeptidase domain containing|CD molecules

IGF2R CD7 LILRB2 LAMP1 PTGFRN CD300C

1.46e-03394576471
GeneFamilyProtein disulfide isomerases

TXNDC5 PDIA2

1.97e-0321572692
GeneFamilyEndogenous ligands|Interleukins

IL11 IL27

8.12e-0343572601
GeneFamilyAdenosine receptors|V-set domain containing

CD7 PTGFRN CD300C

1.48e-02163573590
GeneFamilyShort chain dehydrogenase/reductase superfamily

SDR42E2 HSD11B2

2.40e-0276572743
CoexpressionNABA_MATRISOME

MMP25 IL11 CRIM1 TIMP2 WNT2B GAS6 CTHRC1 C1QC ADAM33 IHH CXCL1 CXCL2 CXCL3 SEMA4C VEGFB

1.70e-0710087615MM17056
CoexpressionNABA_MATRISOME

MMP25 IL11 CRIM1 TIMP2 WNT2B GAS6 CTHRC1 C1QC ADAM33 IHH CXCL1 CXCL2 CXCL3 SEMA4C VEGFB

2.13e-0710267615M5889
CoexpressionSOUCEK_MYC_TARGETS

LILRB2 CXCL1 CXCL2 CXCL3

2.45e-0719764MM1252
CoexpressionZHANG_UTERUS_C4_MYOFIBROBLAST

FKBP10 NPPC TXNDC5 PRDX4 NUCB1 GAS6 CXCL16 CXCL2 TMED3

1.22e-06369769MM16610
CoexpressionNABA_MATRISOME_ASSOCIATED

MMP25 IL11 TIMP2 WNT2B C1QC ADAM33 IHH CXCL1 CXCL2 CXCL3 SEMA4C VEGFB

1.35e-067387612MM17058
CoexpressionNABA_MATRISOME_ASSOCIATED

MMP25 IL11 TIMP2 WNT2B C1QC ADAM33 IHH CXCL1 CXCL2 CXCL3 SEMA4C VEGFB

1.62e-067517612M5885
CoexpressionVART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN

NPR1 TMPRSS6 WNT2B ADGRB1 CXCL1 VEGFB

2.72e-06135766M5825
CoexpressionRODWELL_AGING_KIDNEY_NO_BLOOD_UP

TXNDC5 TIMP2 CTHRC1 C1QC CXCL2 CHRNA3 TMED3

4.02e-06224767M9893
CoexpressionVART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP

NPR1 TIMP2 TMPRSS6 WNT2B CXCL2 CXCL3

8.05e-06163766M12112
CoexpressionLIAN_LIPA_TARGETS_6M

LILRB2 C1QC CXCL1 CXCL2 CXCL3

9.39e-0697765MM1016
CoexpressionRODWELL_AGING_KIDNEY_UP

TXNDC5 TIMP2 CTHRC1 C1QC LAMP1 CXCL16 CXCL1 CHRNA3 TMED3

1.45e-05501769M5389
CoexpressionZHANG_UTERUS_C5_MACROPHAGE

C1QC LAMP1 CXCL16 CXCL1 CXCL2 CXCL3

1.76e-05187766MM16611
CoexpressionZHOU_INFLAMMATORY_RESPONSE_LPS_UP

GIPR TMPRSS6 C1QC CXCL1 CXCL2 CXCL3 HTT IL27

2.33e-05406768M9673
CoexpressionREN_ALVEOLAR_RHABDOMYOSARCOMA_DN

FKBP10 TXNDC5 TIMP2 PRDX4 NUCB1 GAS6 LAMP1 TMED3

2.37e-05407768M19541
CoexpressionGSE11961_MARGINAL_ZONE_BCELL_VS_MEMORY_BCELL_DAY40_DN

IGF2R KCNU1 SUSD1 TELO2 SYNE2 NUCB1

2.57e-05200766M9327
CoexpressionGRUETZMANN_PANCREATIC_CANCER_DN

PRDX4 NUCB1 LAMP1 SSR1 CXCL2 HTT

2.57e-05200766M10431
CoexpressionRASHI_NFKB1_TARGETS

CXCL1 CXCL2 CXCL3

2.58e-0520763MM1114
CoexpressionJOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_DN

IL11 NUCB1 CD300C VEGFB

2.81e-0560764M1515
CoexpressionSAUL_SEN_MAYO

TIMP2 CXCL16 CXCL1 CXCL2 CXCL3

2.97e-05123765MM16098
CoexpressionZENG_GU_ICB_CONTROL_METAGENE_44_PRECICTIVE_ICB_RESPONSE

LPCAT2 TELO2 SYNE2 CXCL1 CXCL2 CXCL3

3.03e-05206766MM17084
CoexpressionSAUL_SEN_MAYO

TIMP2 CXCL16 CXCL1 CXCL2 CXCL3

3.09e-05124765M45803
CoexpressionPHONG_TNF_TARGETS_UP

IL11 CXCL1 CXCL2 CXCL3

3.41e-0563764M2496
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

GABRD TIMP2 WNT2B ADGRB1 PTH2 HSD11B2 IHH CHRNA3

3.98e-05438768M1954
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

GABRD TIMP2 WNT2B ADGRB1 PTH2 HSD11B2 IHH CHRNA3

4.11e-05440768MM832
CoexpressionGRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP

CXCL1 CXCL2 CXCL3

4.54e-0524763M19744
CoexpressionZENG_GU_ICB_CONTROL_METAGENE_25_PRECICTIVE_ICB_RESPONSE

CD7 LPCAT2 C1QC CXCL16 CXCL2 CD300C

4.96e-05225766MM17079
CoexpressionZHANG_UTERUS_C0_SECRETORY_STROMAL3_NPPC_HIGH_CELL

NPPC TXNDC5 NUCB1 GAS6 SSR1 HSD11B2 TMED3

5.58e-05337767MM16606
CoexpressionNABA_SECRETED_FACTORS

IL11 WNT2B IHH CXCL1 CXCL2 CXCL3 VEGFB

5.68e-05338767MM17064
CoexpressionTIAN_TNF_SIGNALING_VIA_NFKB

CXCL1 CXCL2 CXCL3

5.81e-0526763M14435
CoexpressionGAURNIER_PSMD4_TARGETS

CXCL16 CXCL1 CXCL2 CXCL3

6.10e-0573764M11428
CoexpressionLIAN_LIPA_TARGETS_3M

C1QC CXCL1 CXCL2 CXCL3

6.10e-0573764MM1020
CoexpressionNABA_SECRETED_FACTORS

IL11 WNT2B IHH CXCL1 CXCL2 CXCL3 VEGFB

6.23e-05343767M5883
CoexpressionZHENG_IL22_SIGNALING_UP

LILRB2 CXCL1 CXCL2 CXCL3

6.44e-0574764MM762
CoexpressionMURARO_PANCREAS_DUCTAL_CELL

IGF2R CRIM1 LPCAT2 TIMP2 ANKRD9 SYNE2 C1QC CXCL16 HSD11B2 CXCL1 CXCL2 CXCL3 PTGFRN

7.09e-0512767613M39173
CoexpressionDURANTE_ADULT_OLFACTORY_NEUROEPITHELIUM_RESPIRATORY_SECRETORY_CELLS

CXCL1 CXCL2 CXCL3

8.11e-0529763M39280
CoexpressionDESCARTES_MAIN_FETAL_ENDOCARDIAL_CELLS

NPPC NPR1 NUCB1 CTHRC1

8.73e-0580764M40106
CoexpressionTRAVAGLINI_LUNG_PROLIFERATING_MACROPHAGE_CELL

POGLUT3 TIMP2 PRDX4 NUCB1 C1QC LAMP1 CXCL16 CXCL1 CXCL2 CXCL3 TMED3

1.05e-049687611M41693
CoexpressionSEKI_INFLAMMATORY_RESPONSE_LPS_UP

CXCL16 CXCL1 CXCL2 CXCL3

1.21e-0487764MM1253
CoexpressionGROSS_ELK3_TARGETS_DN

CXCL1 CXCL2 CXCL3

1.43e-0435763MM1124
CoexpressionZAK_PBMC_MRKAD5_HIV_1_GAG_POL_NEF_AGE_20_50YO_1DY_UP

LPCAT2 SUSD1 TIMP2 LILRB2 NUCB1 GAS6 TMEM175 C1QC CXCL16 CD300C IL27

1.55e-0410127611M40868
CoexpressionGSE6269_E_COLI_VS_STAPH_AUREUS_INF_PBMC_DN

IGF2R LAMP1 PCNX1 CXCL2 CXCL3

1.58e-04175765M5660
CoexpressionGROSS_HYPOXIA_VIA_ELK3_ONLY_UP

CXCL1 CXCL2 CXCL3

1.70e-0437763MM549
CoexpressionTABULA_MURIS_SENIS_BROWN_ADIPOSE_TISSUE_T_CELL_AGEING

TIMP2 LAMP1 TBC1D17 TMED3

1.70e-0495764MM3675
CoexpressionMEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED

MMP25 AMN LPCAT2 DPEP3 GUCY2D CXCL16 MAP10 CHRNA3

1.79e-04544768M1936
CoexpressionSTK33_NOMO_UP

C1QC CXCL1 CXCL2 CXCL3 PTGFRN CD300C

1.99e-04290766M2855
CoexpressionVERHAAK_AML_WITH_NPM1_MUTATED_UP

IGF2R LILRB2 CXCL2 CXCL3 CD300C

2.15e-04187765M4861
CoexpressionGSE29615_CTRL_VS_LAIV_FLU_VACCINE_PBMC_UP

MMP25 GUCY2D LMTK2 CXCL1 XAB2

2.43e-04192765M4923
CoexpressionCUI_DEVELOPING_HEART_VASCULAR_ENDOTHELIAL_CELL

CRIM1 GAS6 CXCL1 CXCL2 CXCL3

2.49e-04193765M39321
CoexpressionDAZARD_RESPONSE_TO_UV_SCC_UP

SSR1 CXCL1 CXCL2 CXCL3

2.50e-04105764M1361
CoexpressionGHANDHI_DIRECT_IRRADIATION_UP

IL11 CXCL1 CXCL2 CXCL3

2.50e-04105764M2591
CoexpressionMEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED

MMP25 AMN LPCAT2 DPEP3 GUCY2D CXCL16 MAP10 CHRNA3

2.57e-04574768MM820
CoexpressionHORIUCHI_WTAP_TARGETS_UP

IGF2R CXCL16 CXCL1 CXCL2 CXCL3 PTGFRN

2.80e-04309766M1973
CoexpressionGSE3982_BCELL_VS_CENT_MEMORY_CD4_TCELL_DN

IL11 FKBP10 PDIA2 HTT SEMA4C

2.80e-04198765M5545
CoexpressionGSE22886_NAIVE_TCELL_VS_NKCELL_DN

IGF2R CRIM1 LAMP1 FRYL HTT

2.80e-04198765M4415
CoexpressionHARALAMBIEVA_PBMC_M_M_R_II_AGE_11_22YO_VACCINATED_VS_UNVACCINATED_7YR_DN

BRI3BP TIMP2 DPEP3 C1QC CXCL1 PTGFRN CD300C SHISA8 SEMA4C

2.86e-04740769M41202
CoexpressionGSE23321_CENTRAL_MEMORY_VS_NAIVE_CD8_TCELL_UP

TIMP2 PDIA2 CXCL1 CXCL3 TMED3

2.86e-04199765M8435
CoexpressionGSE19401_UNSTIM_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_UP

TIMP2 LAMP1 XPC CD300C VEGFB

2.93e-04200765M7665
CoexpressionGSE5589_LPS_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_UP

PRDX4 C1QC LAMP1 CXCL16 XPC

2.93e-04200765M6611
CoexpressionGSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_AND_RARA_AGONIST_AM580_TREATED_DC_DN

FKBP10 PRDX4 GAS6 SSR1 CXCL2

2.93e-04200765M6560
CoexpressionGSE29618_MONOCYTE_VS_MDC_DAY7_FLU_VACCINE_UP

IGF2R LILRB2 LAMP1 CXCL1 CXCL2

2.93e-04200765M4966
CoexpressionGSE17721_CTRL_VS_LPS_0.5H_BMDC_DN

NPPC SYNE1 TMEM115 SHBG TMED3

2.93e-04200765M3680
CoexpressionSIMBULAN_UV_RESPONSE_NORMAL_UP

CXCL2 CXCL3

2.95e-049762M16664
CoexpressionTRAVAGLINI_LUNG_MACROPHAGE_CELL

C1QC CXCL16 CXCL1 CXCL2 CXCL3

3.00e-04201765M41692
CoexpressionTRAVAGLINI_LUNG_IGSF21_DENDRITIC_CELL

C1QC CXCL16 CXCL2

3.25e-0446763M41696
CoexpressionNIKOLSKY_BREAST_CANCER_16P13_AMPLICON

MMP25 TELO2 PDIA2 NPW

4.03e-04119764M1788
CoexpressionGRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_UP

PRDX4 PTH2 CXCL16 HSD11B2 IHH CXCL1 CXCL2 CXCL3

4.12e-04616768MM977
CoexpressionZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP

CXCL16 CXCL1 CXCL2 CXCL3 SEMA4C

4.82e-04223765M19826
CoexpressionZHANG_UTERUS_C10_STROMAL2_RETNLG_HIGH_CELL

CXCL1 CXCL2 CXCL3

5.22e-0454763MM16616
CoexpressionTABULA_MURIS_SENIS_SPLEEN_MACROPHAGE_AGEING

C1QC LAMP1 CD300C TMED3

5.30e-04128764MM3838
CoexpressionTABULA_MURIS_SENIS_MAMMARY_GLAND_STROMAL_CELL_AGEING

TIMP2 PRDX4 NUCB1 GAS6 LAMP1 TMED3

5.33e-04349766MM3790
CoexpressionPOS_RESPONSE_TO_HISTAMINE_UP

IGF2R FRYL

5.37e-0412762M1782
CoexpressionTABULA_MURIS_SENIS_MAMMARY_GLAND_LUMINAL_EPITHELIAL_CELL_OF_MAMMARY_GLAND_AGEING

TIMP2 GAS6 CXCL1 CXCL2 CXCL3 TMED3

5.58e-04352766MM3788
CoexpressionGSE12707_AT16L1_HYPOMORPH_VS_WT_THYMUS_DN

DPEP3 SYNE2 C1QC NPW

5.62e-04130764M434
CoexpressionCROONQUIST_STROMAL_STIMULATION_UP

CXCL1 CXCL2 CXCL3

5.81e-0456763M5929
CoexpressionHE_LIM_SUN_FETAL_LUNG_C3_OMD_POS_ENDOTHELIAL_CELL

CRIM1 LPCAT2 LMTK2 CXCL2 CXCL3 PTGFRN

5.83e-04355766M45758
CoexpressionTABULA_MURIS_SENIS_BRAIN_MYELOID_MICROGLIAL_CELL_AGEING

TIMP2 C1QC CXCL16 CXCL2 CD300C TMED3

5.92e-04356766MM3684
CoexpressionGSE9946_MATURE_STIMULATORY_VS_LISTERIA_INF_MATURE_DC_DN

HCN4 PTH2 SSR1 CXCL3

5.96e-04132764M425
CoexpressionTABULA_MURIS_SENIS_BROWN_ADIPOSE_TISSUE_MYELOID_CELL_AGEING

C1QC LRRC58 CXCL1 CXCL2 CXCL3

6.72e-04240765MM3678
CoexpressionNABA_MATRISOME_HGSOC_OMENTAL_METASTASIS

TIMP2 CTHRC1 C1QC

6.78e-0459763M47993
CoexpressionONDER_CDH1_TARGETS_3_DN

CXCL1 CXCL2 CXCL3

6.78e-0459763M11790
CoexpressionDASU_IL6_SIGNALING_UP

GAS6 CXCL3 VEGFB

7.47e-0461763M14344
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_DN

FKBP10 TIMP2 PRDX4 TMEM115 LMTK2 EIF2AK3 HTT SEMA4C

7.94e-04681768M5314
CoexpressionHAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP

CXCL1 CXCL2 CXCL3

8.21e-0463763M9775
CoexpressionBILD_HRAS_ONCOGENIC_SIGNATURE

IL11 CXCL1 CXCL2 CXCL3 SEMA4C

8.37e-04252765M12029
CoexpressionHINATA_NFKB_IMMU_INF

CXCL2 CXCL3

8.50e-0415762M2645
CoexpressionGRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP

CXCL1 CXCL2 CXCL3

8.60e-0464763M4406
CoexpressionTABULA_MURIS_SENIS_HEART_MONOCYTE_AGEING

CXCL1 CXCL2 CXCL3 TMED3

8.91e-04147764MM3707
CoexpressionENK_UV_RESPONSE_KERATINOCYTE_UP

NPR1 NUCB1 SSR1 CXCL1 CXCL2 CXCL3 TMED3

9.01e-04533767M10791
CoexpressionP53_DN.V2_UP

TPTE GUCY2D CXCL1 CXCL2

9.13e-04148764M2694
ToppCell10x5'-bone_marrow-Myeloid_Mac-Intermediate_macrophages|bone_marrow / Manually curated celltypes from each tissue

TIMP2 LILRB2 CXCL16 CXCL1 CXCL2 CXCL3 CD300C

2.19e-08174777268abfc4d53a3ba3931dbcafffef09a72ea0edfa
ToppCell10x5'-GI_small-bowel-Myeloid_Mac-Intestinal_macrophages|GI_small-bowel / Manually curated celltypes from each tissue

LPCAT2 TIMP2 LILRB2 C1QC CXCL1 CXCL2 CXCL3

4.97e-08196777075e5746fa5cb121115a1d51b823c0fbf8d54305
ToppCell(6)_Macrophage|World / shred on Cell_type and subtype

LPCAT2 LILRB2 C1QC CXCL16 CXCL2 CXCL3 CD300C

5.15e-08197777010b275d4da4a896175ad7fbaa96d1dc11a0b744
ToppCellMonocytes-Phagocytic_CD16+_macrophages|World / Immune cells in Kidney/Urine in Lupus Nephritis

LPCAT2 TIMP2 LILRB2 C1QC CXCL16 CXCL2 CD300C

5.33e-0819877709009cc966bf1503c3b15dfa079a6c5f6ad1f507
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LPCAT2 LILRB2 C1QC CXCL16 CXCL2 CXCL3 CD300C

5.33e-08198777af682919a874d60f579e854c274dc47063015ea9
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

LPCAT2 TIMP2 LILRB2 CXCL16 CXCL2 CXCL3 CD300C

5.33e-0819877794e2567f057b2c455a9656b121321a28e7cb1d2b
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

LPCAT2 TIMP2 LILRB2 CXCL16 CXCL2 CXCL3 CD300C

5.33e-08198777f3a12a7e23bb4ff6e82fee675dbc090d99587f69
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

LPCAT2 TIMP2 LILRB2 CXCL16 CXCL2 CXCL3 CD300C

5.51e-081997776783d571d28eac891fcc70380f176b53f35c88ba
ToppCellTransverse-Macrophage-Macrophage|Transverse / Region, Cell class and subclass

LPCAT2 LILRB2 C1QC CXCL16 CXCL2 CXCL3 CD300C

5.71e-0820077717548806ba38008050244151d1216c69ef8a8310
ToppCellTransverse-(6)_Macrophage|Transverse / shred on region, Cell_type, and subtype

LPCAT2 LILRB2 C1QC CXCL16 CXCL2 CXCL3 CD300C

5.71e-08200777b28350de555fa756d2631f004f71d5ac69b1affe
ToppCellSigmoid-(4)_Monocyte|Sigmoid / shred on region, Cell_type, and subtype

SUSD1 LILRB2 CXCL16 CXCL2 CXCL3 CD300C IL27

5.71e-082007777f3920a0434d5199c6c8f0b3064a305bb0d87b60
ToppCellSigmoid-Monocyte-Monocyte|Sigmoid / Region, Cell class and subclass

SUSD1 LILRB2 CXCL16 CXCL2 CXCL3 CD300C IL27

5.71e-08200777010ca36970cb8894bdbca08779c0ecf56be22fc9
ToppCellSigmoid-Monocyte|Sigmoid / Region, Cell class and subclass

SUSD1 LILRB2 CXCL16 CXCL2 CXCL3 CD300C IL27

5.71e-08200777c41bd6ec0f2262fce5cadb37a400d487e6662f49
ToppCellTransverse-Macrophage|Transverse / Region, Cell class and subclass

LPCAT2 LILRB2 C1QC CXCL16 CXCL2 CXCL3 CD300C

5.71e-082007771920605e5811938814d02b971069a4506868db5f
ToppCellmetastatic_Lymph_Node-Myeloid_cells-mo-Mac|Myeloid_cells / Location, Cell class and cell subclass

TIMP2 C1QC LAMP1 CXCL16 CXCL1 CXCL2 CXCL3

5.71e-082007774758b96725699641b55a665533adf2d238032b09
ToppCellSigmoid-(4)_Monocyte-(40)_Monocyte|Sigmoid / shred on region, Cell_type, and subtype

SUSD1 LILRB2 CXCL16 CXCL2 CXCL3 CD300C IL27

5.71e-08200777576c0a1098e6a934448705de3673ef798fcf1b26
ToppCellTransverse-(6)_Macrophage-(60)_Macrophage|Transverse / shred on region, Cell_type, and subtype

LPCAT2 LILRB2 C1QC CXCL16 CXCL2 CXCL3 CD300C

5.71e-082007772be675684a2958ea609939bb45248bede78a26bc
ToppCellMyeloid-Myeloid-E_(Neutrophils)|Myeloid / shred on cell class and cell subclass (v4)

MMP25 LPCAT2 TIMP2 SYNE1 LRRC58 CXCL2

2.42e-071507761bffb8d86b737ac43be902d9468041aef3542f1f
ToppCelldroplet-Lung-21m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LPCAT2 DPEP3 GAS6 C1QC CXCL16 CXCL1

4.72e-07168776aaafa7243c44e6852d92e3445335fc4a1018f416
ToppCellnormal_Lymph_Node-Myeloid_cells-CD163+CD14+_DCs|normal_Lymph_Node / Location, Cell class and cell subclass

LPCAT2 LILRB2 SHBG C1QC CXCL2 CXCL3

5.60e-0717377638f88f5bbf92a3bf5109bc4782cd071b7cb1ca34
ToppCell15-Trachea-Mesenchymal-Mesenchyme_RSPO2+|Trachea / Age, Tissue, Lineage and Cell class

POGLUT3 IGF2R TIMP2 ADGRB1 PTGFRN VEGFB

5.80e-07174776fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_macrophage_(16)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LILRB2 C1QC CXCL16 CXCL1 CXCL2 CXCL3

6.20e-0717677698176bf3c961d5262593e2d5d002836adb010e13
ToppCelldroplet-Lung-30m-Hematologic-myeloid-interstitial_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TIMP2 TMPRSS6 GAS6 C1QC CXCL16 CXCL2

6.62e-07178776c85de851b39cb8ef7ea1866ab64c6a387788273a
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MMP25 NPPC LPCAT2 GAS6 C1QC CXCL16

6.84e-071797768bd85ee92791996377bcafed198c1bb3c9af4c3c
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Nonclassical_Monocyte|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

C1QC LAMP1 CXCL16 CXCL2 CXCL3 EIF2AK3

6.84e-071797766624a2e731ab2d6c2eec19445e3dc509f581a8a9
ToppCellnormal_Pleural_Fluid-Myeloid_cells-mo-Mac|normal_Pleural_Fluid / Location, Cell class and cell subclass

TIMP2 C1QC CXCL16 CXCL1 CXCL2 CXCL3

6.84e-07179776cd3c58e044f5a38e815313a1636153d81a592fce
ToppCelldroplet-Lung-30m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_33|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TIMP2 TMPRSS6 GAS6 C1QC CXCL16 CXCL2

6.84e-0717977613d80ae2e43a5daad0aeb5f47338efca2c58800a
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

LPCAT2 LILRB2 C1QC CXCL16 CXCL2 CXCL3

7.07e-071807767be7d7a6906fff6dbdecd9cb013d855aba4eda2a
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid-Macrophages|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LPCAT2 LILRB2 C1QC CXCL16 CXCL3 CD300C

7.07e-071807767af90f0e7ca001bf1fe5c860ee54c4cc8eb483bf
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IGF2R LILRB2 LAMP1 CXCL1 CXCL2 CXCL3

9.11e-071887765f6ad5d693145d846ca561c2fa55465a88e40b90
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_macrophage|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LILRB2 C1QC CXCL16 CXCL1 CXCL2 CXCL3

9.39e-07189776440c422369de1c49112d18cf8c506a2a3a81f6ba
ToppCellmild-Lymphocytic-CD4_T_cells_2|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MMP25 LPCAT2 TIMP2 LILRB2 CXCL16 CXCL1

1.03e-061927764cd8f572e067bf5fe22f62fa868d7d332f097a8c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

LPCAT2 TIMP2 LILRB2 CXCL2 CXCL3 CD300C

1.06e-061937762ebb950476767f330241b0077ced22e55e124359
ToppCellIIH-mono3-|IIH / Condition, Cell_class and T cell subcluster

LPCAT2 TIMP2 ANKRD9 GAS6 C1QC CXCL16

1.13e-0619577628a858b04a7b413916c07a8d880f5ea02e985461
ToppCellCOVID-19_Severe|World / Disease condition and Cell class

MMP25 IGF2R SYNE1 CXCL1 CXCL2 CXCL3

1.13e-0619577622f56ccb81967bff54a1f90e949a8dfc2ce0e4ab
ToppCellIIH-mono3|IIH / Condition, Cell_class and T cell subcluster

LPCAT2 TIMP2 ANKRD9 GAS6 C1QC CXCL16

1.13e-06195776c6dd5af582d257be64b718e30f60220c1bf1738a
ToppCell(2)_5-FU|World / Stress and Cell class

FKBP10 TXNDC5 TIMP2 PRDX4 GAS6 LRRC58

1.13e-06195776e5b1d96fafeb2f3b1f4cdf6b2c9eddef36bca7ff
ToppCellCOVID-19_Severe-Non-classical_Monocyte|COVID-19_Severe / disease group, cell group and cell class

LPCAT2 TIMP2 LILRB2 C1QC CXCL16 CD300C

1.16e-06196776af9e8f5ef9d03862f707e105857309b55595b1b9
ToppCellILEUM-inflamed-(3)_Resident_macrophages|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

LPCAT2 LILRB2 C1QC CXCL16 CXCL2 CXCL3

1.16e-061967765ac246a823a8e1996325753858615269687b429d
ToppCellILEUM-inflamed-(3)_Inf._Macrophages|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

LILRB2 C1QC CXCL16 CXCL1 CXCL2 CXCL3

1.16e-061967766ba84bc229e80b4e71c59301154d165066dd618c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

LPCAT2 TIMP2 LILRB2 C1QC CXCL16 CD300C

1.16e-0619677651fc8bb9a806f8fbf78d5d80d535f1068a9770c2
ToppCellILEUM-non-inflamed-(3)_Resident_macrophages|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

LPCAT2 LILRB2 C1QC CXCL16 CXCL2 CXCL3

1.20e-061977763af24354b6a93c7d105b9fa6549cf215107b9203
ToppCell10x5'-lymph-node_spleen-Myeloid_Monocytic-Nonclassical_monocytes|lymph-node_spleen / Manually curated celltypes from each tissue

LPCAT2 TIMP2 LILRB2 CXCL16 CXCL2 CD300C

1.20e-0619777667f19dd30adb03300f04219d0295bc1c1788f626
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LPCAT2 TIMP2 LILRB2 C1QC CXCL16 CD300C

1.20e-06197776989eaf7ecef8683e3ec6ec024fd193a2f5861b26
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-Monocytes|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LILRB2 CXCL16 CXCL2 CXCL3 CD300C IL27

1.20e-06197776d9d58c2fe40d9b5b9031fb7a71525a535927effe
ToppCell(7)_MNP|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

LPCAT2 TIMP2 LILRB2 C1QC CXCL16 CD300C

1.20e-061977766790346736946984cc80d67668523ba70ab0b380
ToppCellmild_COVID-19-Non-classical_Monocyte|mild_COVID-19 / disease group, cell group and cell class (v2)

LPCAT2 TIMP2 LILRB2 C1QC CXCL16 CD300C

1.23e-06198776d7620b8d24e04ce1c563fc0ebe1625e03fe78950
ToppCellVE-mono1-|VE / Condition, Cell_class and T cell subcluster

LPCAT2 TIMP2 LILRB2 C1QC CXCL16 IL27

1.23e-061987762959d6e4992c36040ec9637f5a2daed02b35cf30
ToppCellVE-mono1|VE / Condition, Cell_class and T cell subcluster

LPCAT2 TIMP2 LILRB2 C1QC CXCL16 IL27

1.23e-06198776c742871b8ec4720b1848991551c7c1f4000ebd85
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_4_(MMP1+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL11 FKBP10 TIMP2 CTHRC1 CXCL1 CXCL3

1.23e-06198776229588189825b1080181db9515185677b742c668
ToppCell10x5'-GI_small-bowel-Myeloid_Mac|GI_small-bowel / Manually curated celltypes from each tissue

LPCAT2 TIMP2 LILRB2 C1QC CXCL16 CD300C

1.23e-06198776748db69d3c9774e44c0cc425d937d18b83af8312
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FKBP10 TXNDC5 TIMP2 CTHRC1 PTGFRN TMED3

1.23e-06198776b086af292a508a156266c2d899ba1caf820bf61c
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FKBP10 TXNDC5 TIMP2 CTHRC1 PTGFRN TMED3

1.23e-061987761b90d632e59c3c47b936e829cceeb0334f05f34f
ToppCell(4)_Monocyte|World / shred on Cell_type and subtype

LILRB2 CXCL16 CXCL1 CXCL2 CXCL3 CD300C

1.23e-0619877656f9ebf902fe81c590696ba4c88028deaf346841
ToppCellnormal_Lymph_Node-Myeloid_cells|normal_Lymph_Node / Location, Cell class and cell subclass

TIMP2 LILRB2 C1QC CXCL16 CXCL2 CXCL3

1.23e-061987766b956073898192b1c6c8da66416b6a9b20d28a82
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FKBP10 TXNDC5 TIMP2 CTHRC1 PTGFRN TMED3

1.23e-06198776524305c5d7b1d53e86ec0af775efefa3e0955e47
ToppCellmLN-B_cell-B_cell_IgA_Plasma|B_cell / Region, Cell class and subclass

GIPR CD7 TXNDC5 GUCY2D GAS6 CTHRC1

1.27e-0619977609494953bc7fff63cf2763ea89fca7abb97c186f
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_macrophage|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TIMP2 C1QC CXCL16 CXCL1 CXCL2 CXCL3

1.27e-06199776bcf7d15b6a08b24e7dd0ce106817659cb976f833
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

LPCAT2 TIMP2 LILRB2 C1QC CXCL16 CD300C

1.27e-06199776c4fc638a8dad3a9b77634e8912a9326c8a2f11f5
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LPCAT2 TIMP2 LILRB2 C1QC CXCL16 CXCL2

1.27e-061997760f3ce61bbae69f7e333ed8dacf7257645624e163
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

LPCAT2 TIMP2 LILRB2 CXCL16 CXCL3 CD300C

1.27e-0619977697af159fa3a5533ec3d45331fb80c6da8a715aa5
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LILRB2 C1QC CXCL16 CXCL2 CXCL3 CD300C

1.27e-06199776928a3dbef54a2c292a71edb398d64dd54c259164
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LPCAT2 TIMP2 LILRB2 C1QC CXCL16 CXCL2

1.27e-0619977680ed217d28ba1c07facd0e103c25a02658dd848d
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LPCAT2 TIMP2 LILRB2 C1QC CXCL16 CD300C

1.27e-0619977618b6087863fda22e3e2a2167e7daeb347df1d95b
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

LPCAT2 TIMP2 LILRB2 C1QC CXCL16 CD300C

1.27e-06199776697a9a58c0cdb77222700d029873355d37f6ab28
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_macrophage-macrophage|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TIMP2 C1QC LAMP1 CXCL16 CXCL2 CXCL3

1.31e-06200776bc56d6d6d32405685e9bd553ebdbe48b8fbe6902
ToppCellSigmoid-(6)_Macrophage-(61)_LYVE1_Macrophage|Sigmoid / shred on region, Cell_type, and subtype

LPCAT2 LILRB2 C1QC CXCL16 CXCL2 CXCL3

1.31e-06200776bc0280d52e4edc2c5edf4ead164a1c7cf3fccd60
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

LILRB2 C1QC CXCL16 CXCL2 CXCL3 CD300C

1.31e-06200776c325dc52e4bf3829a35905b956784ca3e9191926
ToppCellCaecum-Macrophage-Macrophage|Caecum / Region, Cell class and subclass

LILRB2 C1QC CXCL16 CXCL2 CXCL3 CD300C

1.31e-0620077699dcf07b17ecf90d596f3b8a12d5b7aae2a351d5
ToppCellSigmoid-Macrophage|Sigmoid / Region, Cell class and subclass

LPCAT2 LILRB2 C1QC CXCL16 CXCL2 CXCL3

1.31e-06200776b07ac0ff3b8530e99094678fed80f35949cafac8
ToppCellCaecum-(6)_Macrophage-(60)_Macrophage|Caecum / shred on region, Cell_type, and subtype

LILRB2 C1QC CXCL16 CXCL2 CXCL3 CD300C

1.31e-0620077667b6cdeb07ffc5c9af7a3e738dd31256cf391e98
ToppCellSigmoid-Macrophage-LYVE1_Macrophage|Sigmoid / Region, Cell class and subclass

LPCAT2 LILRB2 C1QC CXCL16 CXCL2 CXCL3

1.31e-06200776851a1b372ddbec522829069e69ed36a1f4832131
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_macrophage|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TIMP2 C1QC LAMP1 CXCL16 CXCL2 CXCL3

1.31e-06200776d08c0b10cd95bfb462792e368627b3e36582b263
ToppCellCaecum-(6)_Macrophage|Caecum / shred on region, Cell_type, and subtype

LILRB2 C1QC CXCL16 CXCL2 CXCL3 CD300C

1.31e-062007762ce3930645c3daf6be578f7881e57a58df61e75c
ToppCellCaecum-Macrophage|Caecum / Region, Cell class and subclass

LILRB2 C1QC CXCL16 CXCL2 CXCL3 CD300C

1.31e-06200776d83209559187a4419df2508ecc5eb9f7d72fced3
ToppCellSigmoid-(6)_Macrophage|Sigmoid / shred on region, Cell_type, and subtype

LPCAT2 LILRB2 C1QC CXCL16 CXCL2 CXCL3

1.31e-062007769e10cca4429de2c4c8c3c6cf2c9e28637a095be9
ToppCellILEUM-inflamed-(8)_Fibroblast-(8)_Activated_fibroblasts|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FKBP10 PRDX4 CTHRC1 CXCL2 CXCL3 TMED3

1.31e-062007762518d1758e2730b028270e76b949cebbeb7fb5ce
ToppCellLung_Parenchyma|World / Location, Disease Group, Cell group, Cell class (2021.03.09)

FKBP10 TIMP2 CTHRC1 CXCL2 CXCL3 VEGFB

1.34e-0620177691ec5eebe93a3c7b1a33c27e5da949b123b676a8
ToppCell(60)_Macrophage|World / shred on Cell_type and subtype

LILRB2 C1QC CXCL16 CXCL2 CXCL3 CD300C

1.46e-0620477606d0cb306f1ad0014d81f8228868938e48c2bcf3
ToppCell(30)_ILC|World / shred on Cell_type and subtype

MMP25 CD7 CRIM1 GUCY2D PTH2 CXCL2

1.46e-06204776bd9fbd278c05e396463704d711b60d47699e3c09
ToppCell(40)_Monocyte|World / shred on Cell_type and subtype

LILRB2 CXCL16 CXCL1 CXCL2 CXCL3 CD300C

1.55e-06206776d78a70f951265ef6df8f64404107be4f53e75d28
ToppCellfacs-Marrow-T-cells-24m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE1 C1QC CXCL16 CXCL1 CXCL2

5.32e-061457754f8b188a93a038afbc7a446df8467ad544f5b1cb
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

LPCAT2 LILRB2 GAS6 CXCL3 IL27

8.33e-06159775210ac7fa89514a84f38d9f42254e38fbc2bc5f42
ToppCelldroplet-Kidney-nan-18m-Myeloid-CD45____macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LPCAT2 TIMP2 C1QC CXCL16 CXCL2

8.58e-06160775d18c4cc99a31481dd0ee8af9299695d5f6857b42
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

LPCAT2 LILRB2 GAS6 CXCL3 IL27

8.58e-06160775c9fe3438f747e2a98e3f27a56ba4c12a3789c2f2
ToppCelldroplet-Kidney-nan-18m-Myeloid|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LPCAT2 TIMP2 C1QC CXCL16 CXCL2

8.58e-06160775a707a4ad9fbedcca227f76b49f1393e88101c2fb
ToppCelldroplet-Kidney-nan-18m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LPCAT2 TIMP2 C1QC CXCL16 CXCL2

8.58e-0616077573b604cbdcd9e8f0f317964abc632abee314a557
ToppCelldroplet-Kidney-nan-21m-Myeloid-CD45____macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LPCAT2 TIMP2 C1QC CXCL16 CXCL2

9.68e-06164775d4cdcd61e8c28b3fb912cef8837cc1a49678a729
ToppCelldroplet-Kidney-KIDNEY-30m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LPCAT2 TIMP2 C1QC CXCL16 CXCL2

9.68e-06164775e19fc6ba049336ab989a3a968bdbefd567971d73
ToppCelldroplet-Kidney-KIDNEY-30m-Myeloid|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LPCAT2 TIMP2 C1QC CXCL16 CXCL2

9.68e-06164775d6526551d0b183c3ef027ba3dbfddeac03fd93bb
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

LILRB2 CXCL16 HSD11B2 CXCL2 CXCL3

9.68e-0616477510741c7706a37b24aa08a300b27d60d6b8600167
ToppCell356C-Myeloid-Dendritic-pDC|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

FKBP10 NPPC AMN CD7 FUZ

9.68e-06164775fed26f4ac36a2b0722bc7b9f91659c5e0cf4d53a
ToppCelldroplet-Kidney-KIDNEY-30m-Myeloid-CD45____macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LPCAT2 TIMP2 C1QC CXCL16 CXCL2

9.68e-06164775eba25e4d65ca66b5192a7a4d11423f3fa0956828
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

LILRB2 CXCL16 HSD11B2 CXCL2 CXCL3

9.68e-061647757077683afee91828ad2b95e0f81c2b27aae0f831
ToppCelldroplet-Kidney-nan-21m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LPCAT2 TIMP2 C1QC CXCL16 CXCL2

9.96e-061657759852a4cb680af39c92c7d2d5e5fa8dc04e6602aa
ToppCelldroplet-Kidney-nan-21m-Myeloid|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LPCAT2 TIMP2 C1QC CXCL16 CXCL2

9.96e-06165775c629ed33ff14834c32cc1a91116fb079f7aaa94d
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MMP25 LILRB2 C1QC CXCL16 SHISA8

1.03e-0516677583d0c26ccee605df6b04bbca31661bf4ff4f22ba
ToppCelldroplet-Kidney-nan-3m-Myeloid|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LPCAT2 TIMP2 C1QC CXCL16 CXCL2

1.03e-05166775961f93f7fb127f449cb1021f6ba73775dc666c53
ToppCelldroplet-Kidney-nan-3m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LPCAT2 TIMP2 C1QC CXCL16 CXCL2

1.03e-05166775fc71e871084299fb6f006c76f91e72026a290149
ToppCelldroplet-Kidney-nan-3m-Myeloid-CD45____macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LPCAT2 TIMP2 C1QC CXCL16 CXCL2

1.03e-05166775f55fc58572ae6080ac2758462a6b1f3f8b5a93f3
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

IL11 CXCL1 CXCL2 CXCL3

8.15e-0550504GAVISH_3CA_METAPROGRAM_FIBROBLASTS_HYPOXIA
Drug17alpha-estradiol

MMP25 GABRD IL11 NPR1 IGF2R CD7 TIMP2 TELO2 GUCY2D SHBG PDIA2 HSD11B2 IHH CXCL1 CXCL2 CXCL3 CHRNA3 VEGFB

2.50e-0713037718CID000000450
DrugNimodipine [66085-59-4]; Up 200; 9.6uM; MCF7; HT_HG-U133A

GABRD FKBP10 NPR1 CD7 HCN4 GAS6 IHH CXCL2

3.31e-071967786480_UP
DrugO-Su

XPC CXCL1 CXCL2 CXCL3 EIF2AK3

1.83e-0660775CID000447970
DrugPractolol [6673-35-4]; Up 200; 15uM; PC3; HT_HG-U133A

GABRD GIPR NPR1 LILRB2 WNT2B ADGRB1 IHH

4.86e-061987774603_UP
DrugCP-320650-01 [172079-28-6]; Down 200; 10uM; MCF7; HT_HG-U133A

GABRD IL11 HCN4 LMTK2 PDIA2 LAMP1 VEGFB

5.19e-062007774379_DN
Drugaldosterone

MMP25 GIPR NPPC NPR1 SHBG PTH2 NPW HSD11B2 CABIN1

7.71e-06397779CID000005839
DrugFS-2

CXCL1 CXCL2 CXCL3

8.00e-0612773CID003042059
DrugAC1NBL8T

IGF2R IHH CXCL1 CXCL2 CXCL3

8.64e-0682775CID004469804
DrugToxins, Biological

IL11 NPPC IGF2R CD7 TIMP2 C1QC IHH CXCL1 CXCL2 SEMA4C VEGFB

8.77e-066327711ctd:D014118
DrugMefloquine hydrochloride [51773-92-3]; Up 200; 9.6uM; PC3; HT_HG-U133A

IL11 LILRB2 GUCY2D LMTK2 CXCL2 CXCL3

2.35e-051697765724_UP
DrugPeptide 78

IL11 CXCL16 CXCL1 CXCL2 CXCL3

2.88e-05105775CID003081257
DrugCroton Oil

IL11 CXCL16 CXCL1 CXCL2

3.36e-0554774ctd:D003436
DrugPromethazine hydrochloride [58-33-3]; Down 200; 12.4uM; HL60; HT_HG-U133A

TIMP2 TELO2 LILRB2 NUCB1 GAS6 SEMA4C

4.94e-051937763100_DN
DrugClemastine fumarate [14976-57-9]; Up 200; 8.6uM; HL60; HT_HG-U133A

NPR1 CRIM1 TIMP2 ADGRB1 LAMP1 TBC1D17

4.94e-051937762412_UP
DrugNafcillin sodium salt monohydrate [7177-50-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A

IL11 FKBP10 FUZ LAMP1 CABIN1 TBC1D17

5.23e-051957764103_DN
DrugLidoflazine [3416-26-0]; Up 200; 8.2uM; MCF7; HT_HG-U133A

GIPR NPR1 HCN4 LILRB2 TMPRSS6 CXCL3

5.53e-051977763201_UP
DrugIfenprodil tartrate [23210-58-4]; Up 200; 8.4uM; HL60; HT_HG-U133A

MMP25 GIPR GAS6 LMTK2 LAMP1 TBC1D17

5.69e-051987762372_UP
DrugChlorzoxazone [95-25-0]; Down 200; 23.6uM; PC3; HT_HG-U133A

FKBP10 NUCB1 PCNX1 FRYL XPC CABIN1

5.69e-051987762100_DN
DrugNiridazole [61-57-4]; Up 200; 18.6uM; PC3; HT_HG-U133A

IL11 FKBP10 NPR1 CD7 PCNX1 CHRNA3

5.69e-051987764621_UP
Drugisopropanol

LILRB2 SHBG CXCL1 CXCL2 CXCL3

5.91e-05122775CID000003776
DrugEtifenin [63245-28-3]; Down 200; 12.4uM; MCF7; HT_HG-U133A

CRIM1 GAS6 TMEM115 PCNX1 CABIN1 SEMA4C

6.02e-052007762838_DN
Drug2,3-pentanedione

TIMP2 GAS6 CTHRC1 CXCL1 CXCL3

7.70e-05129775ctd:C013186
Druglipopolysaccharide, Helicobacter pylori

CXCL1 CXCL2 CXCL3

8.11e-0525773ctd:C442865
DrugCAS 80474-14-2

CXCL16 CXCL1 CXCL2 CXCL3 IL27

8.28e-05131775CID000003399
Diseaseviral pneumonia (biomarker_via_orthology)

CXCL1 CXCL2 CXCL3

1.51e-083743DOID:10533 (biomarker_via_orthology)
Diseaseaspiration pneumonia (biomarker_via_orthology)

CXCL1 CXCL2 CXCL3

3.01e-076743DOID:0050152 (biomarker_via_orthology)
Diseaseesophageal cancer (biomarker_via_orthology)

CXCL1 CXCL2 CXCL3

3.01e-076743DOID:5041 (biomarker_via_orthology)
Diseasesevere acute respiratory syndrome (biomarker_via_orthology)

CXCL1 CXCL2 CXCL3

8.40e-078743DOID:2945 (biomarker_via_orthology)
Diseasevitamin D-dependent rickets (implicated_via_orthology)

CXCL1 CXCL2 CXCL3

8.40e-078743DOID:0080883 (implicated_via_orthology)
Diseasepneumonia (biomarker_via_orthology)

CXCL1 CXCL2 CXCL3

2.46e-0611743DOID:552 (biomarker_via_orthology)
Diseasebronchopulmonary dysplasia (biomarker_via_orthology)

CXCL1 CXCL2 CXCL3

3.28e-0612743DOID:11650 (biomarker_via_orthology)
Diseaseprostatitis (biomarker_via_orthology)

CXCL1 CXCL2 CXCL3

3.28e-0612743DOID:14654 (biomarker_via_orthology)
Diseasebacterial pneumonia (biomarker_via_orthology)

CXCL1 CXCL2 CXCL3

5.40e-0614743DOID:874 (biomarker_via_orthology)
Diseasesick sinus syndrome (implicated_via_orthology)

HCN4 HCN1

1.86e-053742DOID:13884 (implicated_via_orthology)
DiseaseCoronavirus infectious disease (biomarker_via_orthology)

CXCL1 CXCL2

1.86e-053742DOID:0080599 (biomarker_via_orthology)
Diseasedilated cardiomyopathy (biomarker_via_orthology)

CXCL1 CXCL2 CXCL3

2.25e-0522743DOID:12930 (biomarker_via_orthology)
DiseaseAutosomal dominant Emery-Dreifuss muscular dystrophy

SYNE1 SYNE2

3.71e-054742cv:CN293514
Diseaseacute necrotizing pancreatitis (biomarker_via_orthology)

CXCL1 CXCL2 CXCL3

3.78e-0526743DOID:0080998 (biomarker_via_orthology)
DiseaseAutosomal Recessive Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

6.17e-055742C1450051
DiseaseAutosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)

SYNE1 SYNE2

6.17e-055742C0410190
DiseaseEmery-Dreifuss muscular dystrophy

SYNE1 SYNE2

9.25e-056742cv:C0410189
DiseaseMuscular Dystrophy, Emery-Dreifuss

SYNE1 SYNE2

9.25e-056742C0410189
Diseaselung disease (biomarker_via_orthology)

CXCL1 CXCL2 CXCL3

9.35e-0535743DOID:850 (biomarker_via_orthology)
Diseasestatus epilepticus (biomarker_via_orthology)

HCN1 CXCL1 CXCL2 CXCL3

1.19e-04100744DOID:1824 (biomarker_via_orthology)
DiseaseShock, Hemorrhagic

CXCL1 CXCL2

1.29e-047742C0036982
DiseaseX-Linked Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

1.29e-047742C0751337
Diseaseschizophrenia, type 2 diabetes mellitus

GIPR HCN1 PTGFRN

1.74e-0443743MONDO_0005090, MONDO_0005148
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

GABRD HCN1

2.21e-049742C3502809
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

GIPR IGF2R SYNE2 HTT VEGFB

2.43e-04222745EFO_0008317, EFO_0020943
Diseasetriglycerides in LDL measurement

IGF2R SYNE2 GAS6

3.81e-0456743EFO_0022320
DiseaseBronchial Hyperreactivity

ADAM33 CXCL1

4.03e-0412742C0085129
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

SYNE1 SYNE2

4.03e-0412742DOID:11726 (implicated_via_orthology)
Diseasechronic obstructive pulmonary disease (is_implicated_in)

ADAM33 CHRNA3 IL27

5.40e-0463743DOID:3083 (is_implicated_in)
DiseaseC-X-C motif chemokine 6 measurement

TELO2 CXCL1

7.28e-0416742EFO_0008059
DiseaseCardiac Hypertrophy

NPR1 GAS6 CABIN1

1.16e-0382743C1383860
DiseaseCardiomegaly

NPR1 GAS6 CABIN1

1.16e-0382743C0018800
Diseasetype 1 diabetes mellitus (is_implicated_in)

IGF2R HSD11B2 EIF2AK3

1.29e-0385743DOID:9744 (is_implicated_in)
Diseaselevel of Sphingomyelin (d40:2) in blood serum

SYNE2 CXCL1

1.52e-0323742OBA_2045181
Diseasebrain stem volume measurement

TXNDC5 EIF2AK3

1.65e-0324742EFO_0010605
DiseaseEdema

IL11 AMN

1.94e-0326742C0013604
DiseaseAnasarca

IL11 AMN

1.94e-0326742C0151603
Diseasehemoglobin A1 measurement

GIPR TMPRSS6 SYNE2 GAS6 SHBG IL27

1.96e-03520746EFO_0007629

Protein segments in the cluster

PeptideGeneStartEntry
RLLLLPLLLALARGL

CD7

6

P09564
ARAGLLLLLLLLLLL

BRI3BP

11

Q8WY22
CLLLRLLRQLLTLLR

NKAPP1

96

Q8N9T2
QRLRGLLLLLLLQLP

CTHRC1

11

Q96CG8
SPGLLVRALLLLLLL

EIF2AK3

6

Q9NZJ5
VRALLLLLLLLGLAA

EIF2AK3

11

Q9NZJ5
RLLLLLLLSLLPVAR

CHRNA3

16

P32297
PLLLLLLLLGRRARA

ADGRB1

16

O14514
SNPRLLRVALLLLLL

CXCL1

11

P09341
RRARGTPLLLLLLLL

ADAM33

6

Q9BZ11
RPGSRVLLLLLLLLL

CXCL16

6

Q9H2A7
TLLLALLILSLFRRL

GIPR

151

P48546
LALLVLLVAPPLLRR

AMN

371

Q9BXJ7
LLTRLLLDHLRLLAP

AP5S1

141

Q9NUS5
RPAGSRLRLLLLLLL

NPR1

6

P16066
LLACALLLTLLSLRP

NPPC

6

P23582
LQLLRSDLRLGRPLL

HSD11B2

21

P80365
SNPRLLRVALLLLLL

CXCL3

11

P19876
LRVALLLLLLVAASR

CXCL3

16

P19876
NVRFLLLVLLELPLL

CD300C

181

Q08708
MRLRLRLLALLLLLL

MMP25

1

Q9NPA2
RLLALLLLLLAPPAR

MMP25

6

Q9NPA2
CRLLRTPLATLLLQL

MAP10

106

Q9P2G4
PASRPRLALLLLLLL

NPW

11

Q8N729
RALPRLPLLLLLLLL

GUCY2D

31

Q02846
LLRRLQLLMSRLALP

IL11

136

P20809
VLSLPQIRLNRLLTI

PCNX1

926

Q96RV3
RLLLSCLLLPAARLA

MYMX

11

A0A1B0GTQ4
LALRLLNKLLIHLPL

FRYL

2021

O94915
LLLLLLLLFLILRHR

LILRB2

471

Q8N423
ALRRRLLLLLLVLLI

LMTK2

6

Q8IWU2
RLLAPLLLLCAQQLR

GABRD

6

O14764
LRLLELPQILQILRA

KCNU1

201

A8MYU2
MSRQLLPVLLLLLLR

PDIA2

1

Q13087
LLLPLLLLLLLRAVL

NUCB1

11

Q02818
LLLLLLRAVLAVPLE

NUCB1

16

Q02818
KILSLLRLLRLSRLI

HCN4

381

Q9Y3Q4
LLRLLLPHNRLVSLP

LRRC58

46

Q96CX6
LPIRVLLVALILLLA

LPCAT2

66

Q7L5N7
LLLLLLLPLRGQANT

C1QC

16

P02747
LLRLPLLQLLLLVVQ

FKBP10

11

Q96AY3
LLRNIIISLARLPLV

HTT

2391

P42858
KILSLLRLLRLSRLI

HCN1

261

O60741
SNPRLLRVALLLLLL

CXCL2

11

P19875
LRVALLLLLLVAASR

CXCL2

16

P19875
RPAQLLLLQDSLLRL

CABIN1

736

Q9Y6J0
ALRRAPQLLLLLLAA

GAS6

11

Q14393
RLSLLLLPLLLVQAG

IL27

11

Q8NEV9
LLVSLLGLLLLLARS

CRIM1

16

Q9NZV1
QRRLLLLDLLALYTP

ANKRD9

226

Q96BM1
SARRPLLLLLLLLLL

LAMP1

6

P11279
ARTLLRLLLRLLLFL

SDR42E2

386

A6NKP2
RLLLRLLLFLGLLAL

SDR42E2

391

A6NKP2
YLRRLLLLLLLLLLR

DPEP3

16

Q9H4B8
LLLLLLLLLRQPVTR

DPEP3

21

Q9H4B8
VALQLGLRRLLLLLS

FUZ

381

Q9BT04
LRPRLHFCLVLLLLL

IHH

6

Q14623
SRPLLLALLSLALCR

PTGFRN

6

Q9P2B2
ARRPQRSLLLLQLLL

IGF2R

16

P11717
RSLLLLQLLLLVAAP

IGF2R

21

P11717
QLISRRPLLLNSVLL

XAB2

336

Q9HCS7
MRLLPRLLLLLLLVF

SSR1

1

P43307
RHRRLLLLPLLLFLL

PRDX4

16

Q13162
LFRVLRAALPLQLLL

SYNE1

8741

Q8NF91
RAALPLQLLLLLLIG

SYNE1

8746

Q8NF91
RVVRAALPLQLLLLL

SYNE2

6831

Q8WXH0
VRLRALRLALLILLT

GNRHR2

171

Q96P88
RLLLLLLLLLLRHTR

SHBG

11

P04278
PGLRLALALRLALLL

SHISA8

16

B8ZZ34
LALRALLLLQRLKNR

TELO2

816

Q9Y4R8
CLVLLLLVLSLRRRL

SEMA4C

676

Q9C0C4
LILAVALLRSQPLRS

C11orf94

21

C9JXX5
RALLLQLRLALLVAA

POGLUT3

6

Q7Z4H8
LLSLLLPRQNRLRIE

TCP11

121

Q8WWU5
RQLGRLLLLLRVLDP

TBC1D17

461

Q9HA65
THLLRLLRLIILLRI

TPTE

191

P56180
LLRLLVGLALATLRV

TMEM175

461

Q9BSA9
SRRLLPLLLLLGLAR

SUSD1

11

Q6UWL2
PRSASVLLLLLLLRR

TMED3

6

Q9Y3Q3
LLLLLRLATLLQSPA

TMEM115

176

Q12893
VSRSPRVRLLLLLLL

PTH2

6

Q96A98
RVRLLLLLLLLLVVP

PTH2

11

Q96A98
RTLRLALGLLLLATL

TIMP2

6

P16035
MSPLLRRLLLAALLQ

VEGFB

1

P49765
RRLLLAALLQLAPAQ

VEGFB

6

P49765
LLARPAALTALLLLL

TXNDC5

11

Q8NBS9
IFLLILRALQLLTRL

XPC

301

Q01831
LRALQLLTRLVLSLQ

XPC

306

Q01831
LACLLLLLLLTLPAR

WNT2B

41

Q93097
LRLVPLFVLLALLVL

TMPRSS6

51

Q8IU80