Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsuperoxide-generating NADPH oxidase activator activity

NCF1C NCF1B NCF1

8.19e-0710393GO:0016176
GeneOntologyMolecularFunctionsuperoxide-generating NAD(P)H oxidase activity

NCF1C NCF1B NCF1

1.50e-0612393GO:0016175
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H, oxygen as acceptor

NCF1C NCF1B NCF1

7.67e-0620393GO:0050664
GeneOntologyMolecularFunctionphosphatidylinositol-3,4-bisphosphate binding

NCF1C NCF1B NCF1

4.32e-0535393GO:0043325
GeneOntologyMolecularFunctionmolecular function activator activity

F2 CTSG NCF1C NCF1B ARHGAP21 RPTOR FGF17 NCF1 RAMAC

4.97e-041233399GO:0140677
GeneOntologyMolecularFunctionintracellularly calcium-gated channel activity

ANO9 ANO8

6.91e-0420392GO:0141147
GeneOntologyMolecularFunctionintracellularly calcium-gated chloride channel activity

ANO9 ANO8

6.91e-0420392GO:0005229
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H

NCF1C NCF1B NCF1

8.42e-0495393GO:0016651
GeneOntologyMolecularFunctionphospholipid scramblase activity

ANO9 ANO8

9.16e-0423392GO:0017128
GeneOntologyMolecularFunctionenzyme activator activity

NCF1C NCF1B ARHGAP21 RPTOR NCF1 RAMAC

1.59e-03656396GO:0008047
GeneOntologyMolecularFunctionfibronectin binding

IGFBP6 EPHA1

2.50e-0338392GO:0001968
GeneOntologyMolecularFunctionSH3 domain binding

NCF1C NCF1B NCF1

2.72e-03143393GO:0017124
GeneOntologyBiologicalProcessneutrophil-mediated killing of gram-positive bacterium

CTSG NCF1C NCF1B NCF1

4.89e-115384GO:0070946
GeneOntologyBiologicalProcessneutrophil-mediated killing of bacterium

F2 CTSG NCF1C NCF1B NCF1

6.95e-1116385GO:0070944
GeneOntologyBiologicalProcessneutrophil-mediated killing of symbiont cell

F2 CTSG NCF1C NCF1B NCF1

1.84e-1019385GO:0070943
GeneOntologyBiologicalProcessneutrophil mediated cytotoxicity

F2 CTSG NCF1C NCF1B NCF1

3.22e-1021385GO:0070942
GeneOntologyBiologicalProcesskilling by host of symbiont cells

F2 CTSG NCF1C NCF1B NCF1

7.75e-0938385GO:0051873
GeneOntologyBiologicalProcessneutrophil mediated immunity

F2 CTSG NCF1C NCF1B NCF1

2.61e-0848385GO:0002446
GeneOntologyBiologicalProcessneutrophil-mediated killing of fungus

NCF1C NCF1B NCF1

2.01e-077383GO:0070947
GeneOntologyBiologicalProcessNADP catabolic process

NCF1C NCF1B NCF1

2.01e-077383GO:0006742
GeneOntologyBiologicalProcessregulation of respiratory burst involved in inflammatory response

NCF1C NCF1B NCF1

9.42e-0711383GO:0060264
GeneOntologyBiologicalProcessrespiratory burst involved in inflammatory response

NCF1C NCF1B NCF1

1.63e-0613383GO:0002536
GeneOntologyBiologicalProcessNADP metabolic process

NCF1C NCF1B RPTOR NCF1

3.36e-0656384GO:0006739
GeneOntologyBiologicalProcessdisruption of cell in another organism

F2 CTSG NCF1C NCF1B NCF1

3.77e-06129385GO:0141061
GeneOntologyBiologicalProcesskilling of cells of another organism

F2 CTSG NCF1C NCF1B NCF1

3.77e-06129385GO:0031640
GeneOntologyBiologicalProcessdisruption of anatomical structure in another organism

F2 CTSG NCF1C NCF1B NCF1

4.21e-06132385GO:0141060
GeneOntologyBiologicalProcessresponse to yeast

NCF1C NCF1B NCF1

4.62e-0618383GO:0001878
GeneOntologyBiologicalProcessbiological process involved in interaction with symbiont

F2 CTSG NCF1C NCF1B NCF1

4.71e-06135385GO:0051702
GeneOntologyBiologicalProcessrespiratory burst involved in defense response

NCF1C NCF1B NCF1

6.44e-0620383GO:0002679
GeneOntologyBiologicalProcessmyeloid leukocyte mediated immunity

F2 CTSG NCF1C NCF1B NCF1

7.37e-06148385GO:0002444
GeneOntologyBiologicalProcessnegative regulation of smooth muscle contraction

NCF1C NCF1B NCF1

8.67e-0622383GO:0045986
GeneOntologyBiologicalProcesshydrogen peroxide biosynthetic process

NCF1C NCF1B NCF1

8.67e-0622383GO:0050665
GeneOntologyBiologicalProcessdefense response to fungus

CTSG NCF1C NCF1B NCF1

8.71e-0671384GO:0050832
GeneOntologyBiologicalProcessregulation of respiratory burst

NCF1C NCF1B NCF1

9.96e-0623383GO:0060263
GeneOntologyBiologicalProcessresponse to fungus

CTSG NCF1C NCF1B NCF1

1.78e-0585384GO:0009620
GeneOntologyBiologicalProcessleukocyte mediated cytotoxicity

F2 CTSG NCF1C NCF1B NCF1

2.29e-05187385GO:0001909
GeneOntologyBiologicalProcessnegative regulation of muscle contraction

NCF1C NCF1B NCF1

3.63e-0535383GO:0045932
GeneOntologyBiologicalProcessleukotriene metabolic process

NCF1C NCF1B NCF1

5.86e-0541383GO:0006691
GeneOntologyBiologicalProcesspyridine nucleotide catabolic process

NCF1C NCF1B RPTOR NCF1

6.68e-05119384GO:0019364
GeneOntologyBiologicalProcessrespiratory burst

NCF1C NCF1B NCF1

6.77e-0543383GO:0045730
GeneOntologyBiologicalProcesspyridine-containing compound catabolic process

NCF1C NCF1B RPTOR NCF1

7.60e-05123384GO:0072526
GeneOntologyBiologicalProcessproduction of molecular mediator involved in inflammatory response

F2 NCF1C NCF1B NCF1

1.03e-04133384GO:0002532
GeneOntologyBiologicalProcesssuperoxide anion generation

NCF1C NCF1B NCF1

1.07e-0450383GO:0042554
GeneOntologyBiologicalProcessdefense response to Gram-positive bacterium

CTSG NCF1C NCF1B NCF1

1.64e-04150384GO:0050830
GeneOntologyBiologicalProcesscellular defense response

NCF1C NCF1B NCF1

1.84e-0460383GO:0006968
GeneOntologyBiologicalProcesscell killing

F2 CTSG NCF1C NCF1B NCF1

2.37e-04307385GO:0001906
GeneOntologyBiologicalProcesshydrogen peroxide metabolic process

NCF1C NCF1B NCF1

2.55e-0467383GO:0042743
GeneOntologyBiologicalProcesspurine nucleotide catabolic process

NCF1C NCF1B RPTOR NCF1

3.42e-04182384GO:0006195
GeneOntologyBiologicalProcesspurine-containing compound catabolic process

NCF1C NCF1B RPTOR NCF1

3.87e-04188384GO:0072523
GeneOntologyBiologicalProcessregulation of smooth muscle contraction

NCF1C NCF1B NCF1

4.14e-0479383GO:0006940
GeneOntologyBiologicalProcessreactive oxygen species biosynthetic process

NCF1C NCF1B NCF1

4.30e-0480383GO:1903409
GeneOntologyBiologicalProcessbiological process involved in symbiotic interaction

F2 CTSG NCF1C NCF1B NCF1

4.39e-04351385GO:0044403
GeneOntologyBiologicalProcesssuperoxide metabolic process

NCF1C NCF1B NCF1

4.79e-0483383GO:0006801
GeneOntologyBiologicalProcessnicotinamide nucleotide metabolic process

NCF1C NCF1B RPTOR NCF1

5.08e-04202384GO:0046496
GeneOntologyBiologicalProcesspyridine nucleotide metabolic process

NCF1C NCF1B RPTOR NCF1

5.08e-04202384GO:0019362
GeneOntologyBiologicalProcessnucleotide catabolic process

NCF1C NCF1B RPTOR NCF1

5.67e-04208384GO:0009166
GeneOntologyBiologicalProcesspyridine-containing compound metabolic process

NCF1C NCF1B RPTOR NCF1

5.88e-04210384GO:0072524
GeneOntologyBiologicalProcessnucleoside phosphate catabolic process

NCF1C NCF1B RPTOR NCF1

6.53e-04216384GO:1901292
GeneOntologyBiologicalProcessdefense response to bacterium

F2 CTSG NCF1C NCF1B NCF1

8.38e-04405385GO:0042742
GeneOntologyBiologicalProcessregulation of stress fiber assembly

SYNPO PPP1R9A EPHA1

1.00e-03107383GO:0051492
GeneOntologyBiologicalProcessregulation of insulin-like growth factor receptor signaling pathway

IGFBP6 CILP

1.30e-0329382GO:0043567
GeneOntologyBiologicalProcessnegative regulation of protein localization

UBE2J1 FRMD4A SAPCD2 RPTOR

1.36e-03263384GO:1903828
GeneOntologyBiologicalProcessregulation of actomyosin structure organization

SYNPO PPP1R9A EPHA1

1.46e-03122383GO:0110020
GeneOntologyBiologicalProcessregulation of actin filament bundle assembly

SYNPO PPP1R9A EPHA1

1.50e-03123383GO:0032231
GeneOntologyBiologicalProcesscontractile actin filament bundle assembly

SYNPO PPP1R9A EPHA1

1.64e-03127383GO:0030038
GeneOntologyBiologicalProcessstress fiber assembly

SYNPO PPP1R9A EPHA1

1.64e-03127383GO:0043149
GeneOntologyBiologicalProcessorganophosphate catabolic process

NCF1C NCF1B RPTOR NCF1

1.73e-03281384GO:0046434
GeneOntologyBiologicalProcesssmooth muscle contraction

NCF1C NCF1B NCF1

1.87e-03133383GO:0006939
GeneOntologyBiologicalProcessreactive oxygen species metabolic process

F2 NCF1C NCF1B NCF1

1.96e-03291384GO:0072593
GeneOntologyBiologicalProcessicosanoid metabolic process

NCF1C NCF1B NCF1

2.26e-03142383GO:0006690
GeneOntologyBiologicalProcesscell surface receptor protein tyrosine kinase signaling pathway

FLT4 IGFBP6 CILP SLC30A10 FGF17 EPHA1

2.27e-03747386GO:0007169
GeneOntologyBiologicalProcessnegative regulation of protein transport

UBE2J1 FRMD4A RPTOR

2.79e-03153383GO:0051224
GeneOntologyBiologicalProcesspositive regulation of phosphorylation

FLT4 F2 RPTOR FGF17 NCF1 EPHA1

2.82e-03780386GO:0042327
GeneOntologyCellularComponentNADPH oxidase complex

NCF1C NCF1B NCF1

4.81e-0618393GO:0043020
GeneOntologyCellularComponentbicellular tight junction

PARD6B FRMD4A SYNPO SAPCD2

1.02e-04131394GO:0005923
GeneOntologyCellularComponenttight junction

PARD6B FRMD4A SYNPO SAPCD2

1.29e-04139394GO:0070160
GeneOntologyCellularComponentapical junction complex

PARD6B FRMD4A SYNPO SAPCD2

2.10e-04158394GO:0043296
MousePhenoincreased angiotensin I-converting enzyme activity

NCF1C NCF1B NCF1

2.62e-076343MP:0003184
MousePhenoabnormal angiotensin I-converting enzyme activity

NCF1C NCF1B NCF1

2.62e-076343MP:0013254
MousePhenoliver abscess

NCF1C NCF1B NCF1

4.57e-077343MP:0003332
MousePhenoimpaired granulocyte bactericidal activity

NCF1C NCF1B NCF1

1.56e-0610343MP:0005074
MousePhenodecreased susceptibility to Orthomyxoviridae infection

NCF1C NCF1B NCF1

1.05e-0518343MP:0020947
MousePhenodecreased vasoconstriction

NCF1C NCF1B NCF1

1.96e-0522343MP:0003026
MousePhenoreduced long-term potentiation

SYNPO NCF1C NCF1B PPP1R9A NCF1

2.14e-05141345MP:0001473
MousePhenoincreased circulating renin level

NCF1C NCF1B NCF1

2.25e-0523343MP:0003352
MousePhenoabnormal circulating renin level

NCF1C NCF1B NCF1

4.60e-0529343MP:0003349
MousePhenoskin lesions

AEBP1 NCF1C NCF1B NCF1

6.71e-0591344MP:0001212
MousePhenoimpaired smooth muscle contractility

NCF1C NCF1B NCF1

8.16e-0535343MP:0000740
MousePhenogranulomatous inflammation

NCF1C NCF1B NCF1

8.89e-0536343MP:0002500
MousePhenopale yolk sac

FLT4 F2 UBR5 DNMT1

1.40e-04110344MP:0001722
MousePhenoabnormal long-term potentiation

SYNPO NCF1C NCF1B PPP1R9A NCF1

1.81e-04221345MP:0002207
MousePhenoincreased heart atrium size

NCF1C NCF1B NCF1

1.86e-0446343MP:0008725
MousePhenoabnormal vascular endothelial cell physiology

NCF1C NCF1B NCF1

1.98e-0447343MP:0004003
MousePhenoabnormal vasoconstriction

NCF1C NCF1B NCF1

2.38e-0450343MP:0000250
MousePhenoabnormal susceptibility to Orthomyxoviridae infection

NCF1C NCF1B NCF1

3.00e-0454343MP:0020945
MousePhenoabnormal heart atrium size

NCF1C NCF1B NCF1

3.00e-0454343MP:0031576
MousePhenosingle kidney

NCF1C NCF1B NCF1

4.30e-0461343MP:0003604
MousePhenooxidative stress

TP53INP1 NCF1C NCF1B NCF1

4.83e-04152344MP:0003674
MousePhenoabnormal bile duct morphology

NCF1C NCF1B NCF1

4.95e-0464343MP:0002928
MousePhenoabnormal spatial learning

SYNPO NCF1C NCF1B NCF1 DNMT1

5.04e-04276345MP:0001463
MousePhenoabnormal intestinal goblet cell morphology

NCF1C NCF1B NCF1

5.42e-0466343MP:0003449
MousePhenoabnormal intestinal mucosa morphology

TP53INP1 NCF1C NCF1B NCF1

6.15e-04162344MP:0000511
MousePhenoenhanced long-term potentiation

NCF1C NCF1B NCF1

6.17e-0469343MP:0003008
MousePhenoabnormal vascular wound healing

NCF1C NCF1B NCF1

7.28e-0473343MP:0004883
MousePhenoabnormal redox activity

TP53INP1 NCF1C NCF1B NCF1

7.86e-04173344MP:0003186
MousePhenochronic inflammation

NCF1C NCF1B NCF1

9.16e-0479343MP:0002499
MousePhenodecreased susceptibility to Riboviria infection

NCF1C NCF1B NCF1

1.02e-0382343MP:0020914
MousePhenoimpaired cued conditioning behavior

NCF1C NCF1B NCF1

1.02e-0382343MP:0009456
MousePhenoabnormal wound healing

AEBP1 NCF1C NCF1B NCF1

1.18e-03193344MP:0005023
MousePhenoabnormal response to cardiac infarction

NCF1C NCF1B NCF1

1.52e-0394343MP:0000343
MousePhenoabnormal vascular development

FLT4 F2 UBR5 NCF1C NCF1B NCF1

1.76e-03542346MP:0000259
MousePhenodilated heart

NCF1C NCF1B GYS1 NCF1

1.79e-03216344MP:0004937
MousePhenoabnormal intestine morphology

FLT4 TP53INP1 AEBP1 NCF1C NCF1B NCF1

1.83e-03546346MP:0000477
MousePhenoabnormal angiogenesis

FLT4 UBR5 NCF1C NCF1B NCF1

1.91e-03372345MP:0000260
MousePhenodilated heart left ventricle

NCF1C NCF1B NCF1

2.25e-03108343MP:0002753
MousePhenoabnormal heart atrium morphology

NCF1C NCF1B GYS1 NCF1

2.32e-03232344MP:0003105
MousePhenopericardial effusion

FLT4 F2 UBR5

2.44e-03111343MP:0005312
MousePhenoabnormal visceral yolk sac morphology

FLT4 F2 UBR5 DNMT1

2.47e-03236344MP:0001718
MousePhenoabnormal locomotor activation

NCF1C NCF1B NCF1

2.50e-03112343MP:0003313
MousePhenoabnormal biliary tract morphology

NCF1C NCF1B NCF1

2.83e-03117343MP:0005083
DomainAnoctamin

ANO9 ANO8

1.70e-0410372PF04547
DomainAnoctamin

ANO9 ANO8

1.70e-0410372IPR007632
DomainCarboxyPept-like_regulatory

CILP AEBP1

5.10e-0417372IPR008969
DomainPDZ

PARD6B ARHGAP21 PPP1R9A

2.71e-03141373PF00595
DomainPDZ

PARD6B ARHGAP21 PPP1R9A

3.11e-03148373SM00228
Domain-

PARD6B ARHGAP21 PPP1R9A

3.23e-031503732.30.42.10
DomainPDZ

PARD6B ARHGAP21 PPP1R9A

3.29e-03151373PS50106
DomainPDZ

PARD6B ARHGAP21 PPP1R9A

3.35e-03152373IPR001478
Domain-

PHLDB3 FRMD4A ARHGEF17 ARHGAP21

7.24e-033913742.30.29.30
Domain-

AEBP1 EPHA1

9.19e-03733722.60.120.260
DomainPH_dom-like

PHLDB3 FRMD4A ARHGEF17 ARHGAP21

9.73e-03426374IPR011993
DomainTyrKc

FLT4 EPHA1

1.31e-0288372SM00219
DomainTyr_kinase_cat_dom

FLT4 EPHA1

1.31e-0288372IPR020635
DomainSAM

PPP1R9A EPHA1

1.31e-0288372SM00454
DomainTRYPSIN_SER

F2 CTSG

1.37e-0290372IPR033116
PathwayREACTOME_CROSS_PRESENTATION_OF_PARTICULATE_EXOGENOUS_ANTIGENS_PHAGOSOMES

NCF1C NCF1B NCF1

6.52e-079293MM14524
PathwayREACTOME_RHO_GTPASES_ACTIVATE_NADPH_OXIDASES

NCF1C NCF1B NCF1

1.75e-0525293MM15269
PathwayREACTOME_RAC2_GTPASE_CYCLE

NCF1C NCF1B ARHGAP21 NCF1

2.86e-0587294MM15600
PathwayREACTOME_RAC3_GTPASE_CYCLE

NCF1C NCF1B ARHGAP21 NCF1

3.72e-0593294MM15609
PathwayBIOCARTA_FMLP_PATHWAY

NCF1C NCF1B NCF1

4.49e-0534293MM1399
PathwayREACTOME_DETOXIFICATION_OF_REACTIVE_OXYGEN_SPECIES

NCF1C NCF1B NCF1

4.90e-0535293MM14944
PathwayREACTOME_SIGNALING_BY_VEGF

FLT4 NCF1C NCF1B NCF1

5.55e-05103294MM14752
PathwayREACTOME_ROS_AND_RNS_PRODUCTION_IN_PHAGOCYTES

NCF1C NCF1B NCF1

6.29e-0538293MM14519
PathwayWP_MICROGLIA_PATHOGEN_PHAGOCYTOSIS_PATHWAY

NCF1C NCF1B NCF1

1.12e-0446293MM15837
PathwayREACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_TRANSPORT_AND_UPTAKE_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS

IGFBP6 F2 CTSG ANO8

1.14e-04124294M27285
PathwayREACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES

FLT4 CILP NCF1C NCF1B FGF17 NCF1

1.74e-04418296MM15587
PathwayREACTOME_RHO_GTPASE_CYCLE

PARD6B ARHGEF17 NCF1C NCF1B ARHGAP21 NCF1

2.28e-04439296MM15595
PathwayREACTOME_INDUCTION_OF_CELL_CELL_FUSION

ANO9 ANO8

3.14e-0413292M46426
PathwayREACTOME_RAC1_GTPASE_CYCLE

NCF1C NCF1B ARHGAP21 NCF1

4.28e-04175294MM15599
PathwayREACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION

NCF1C NCF1B NCF1

4.97e-0476293MM14526
PathwayWP_CHEMOKINE_SIGNALING_PATHWAY

CXCR5 NCF1C NCF1B NCF1

5.17e-04184294MM15943
PathwayWP_OXIDATIVE_STRESS_AND_REDOX_PATHWAY

NCF1C NCF1B NCF1

8.69e-0492293MM15823
PathwayREACTOME_STIMULI_SENSING_CHANNELS

ANO9 TRPM3 ANO8

1.08e-0399293MM14910
PathwayREACTOME_STIMULI_SENSING_CHANNELS

ANO9 TRPM3 ANO8

1.31e-03106293M27200
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

PARD6B ARHGEF17 NCF1C NCF1B ARHGAP21 NCF1

1.78e-03649296MM15690
Pubmed

Impaired immunity and enhanced resistance to endotoxin in the absence of neutrophil elastase and cathepsin G.

CTSG NCF1C NCF1B NCF1

6.74e-12539410714686
Pubmed

Role of NADPH oxidase versus neutrophil proteases in antimicrobial host defense.

CTSG NCF1C NCF1B NCF1

2.02e-11639422163282
Pubmed

Killing activity of neutrophils is mediated through activation of proteases by K+ flux.

CTSG NCF1C NCF1B NCF1

4.71e-11739411907569
Pubmed

Reactive oxygen species and p47phox activation are essential for the Mycobacterium tuberculosis-induced pro-inflammatory response in murine microglia.

NCF1C NCF1B NCF1

1.30e-09339318036262
Pubmed

Transient loss of resistance to pulmonary tuberculosis in p47(phox-/-) mice.

NCF1C NCF1B NCF1

1.30e-09339310678931
Pubmed

Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome.

NCF1C NCF1B NCF1

1.30e-09339327044504
Pubmed

Suppression of microglial inflammatory activity by myelin phagocytosis: role of p47-PHOX-mediated generation of reactive oxygen species.

NCF1C NCF1B NCF1

1.30e-09339317167081
Pubmed

Mice lacking NCF1 exhibit reduced growth of implanted melanoma and carcinoma tumors.

NCF1C NCF1B NCF1

1.30e-09339324358335
Pubmed

Molecular characterization of the mouse p47-phox (Ncf1) gene and comparative analysis of the mouse p47-phox (Ncf1) gene to the human NCF1 gene.

NCF1C NCF1B NCF1

1.30e-09339310891396
Pubmed

P47phox-/- mice are compromised in expansion and activation of CD8+ T cells and susceptible to Trypanosoma cruzi infection.

NCF1C NCF1B NCF1

1.30e-09339325474113
Pubmed

NADPH oxidase in bone marrow-derived cells mediates pulmonary ischemia-reperfusion injury.

NCF1C NCF1B NCF1

1.30e-09339318787174
Pubmed

NAD(P)H oxidase subunit p47phox is elevated, and p47phox knockout prevents diaphragm contractile dysfunction in heart failure.

NCF1C NCF1B NCF1

1.30e-09339326209274
Pubmed

Deficient production of reactive oxygen species leads to severe chronic DSS-induced colitis in Ncf1/p47phox-mutant mice.

NCF1C NCF1B NCF1

1.30e-09339324873968
Pubmed

p47(phox) is required for afferent arteriolar contractile responses to angiotensin II and perfusion pressure in mice.

NCF1C NCF1B NCF1

1.30e-09339322184329
Pubmed

NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease.

NCF1C NCF1B NCF1

1.30e-09339311018074
Pubmed

Natural Loss-of-Function Mutations in Qa2 and NCF1 Cause the Spread of Mannan-Induced Psoriasis.

NCF1C NCF1B NCF1

1.30e-09339333545139
Pubmed

Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis.

NCF1C NCF1B NCF1

1.30e-09339320142487
Pubmed

Enhanced host defense after gene transfer in the murine p47phox-deficient model of chronic granulomatous disease.

NCF1C NCF1B NCF1

1.30e-0933939116268
Pubmed

Mice producing less reactive oxygen species are relatively resistant to collagen glycopeptide vaccination against arthritis.

NCF1C NCF1B NCF1

1.30e-09339320686129
Pubmed

Angiotensin II induced catabolic effect and muscle atrophy are redox dependent.

NCF1C NCF1B NCF1

1.30e-09339321570954
Pubmed

p47(phox) contributes to albuminuria and kidney fibrosis in mice.

NCF1C NCF1B NCF1

1.30e-09339325565313
Pubmed

Knockout of neutrophil cytosolic factor 1 ameliorates neuroinflammation and motor deficit after traumatic brain injury.

NCF1C NCF1B NCF1

1.30e-09339339357591
Pubmed

Oscillatory shear stress stimulates endothelial production of O2- from p47phox-dependent NAD(P)H oxidases, leading to monocyte adhesion.

NCF1C NCF1B NCF1

1.30e-09339312958309
Pubmed

Genetic demonstration of p47phox-dependent superoxide anion production in murine vascular smooth muscle cells.

NCF1C NCF1B NCF1

1.30e-09339311435342
Pubmed

Neutrophil Cytosolic Factor 1 in Dendritic Cells Promotes Autoreactive CD8+ T Cell Activation via Cross-Presentation in Type 1 Diabetes.

NCF1C NCF1B NCF1

1.30e-09339331118934
Pubmed

Female mice lacking p47phox have altered adipose tissue gene expression and are protected against high fat-induced obesity.

NCF1C NCF1B NCF1

1.30e-09339323482812
Pubmed

Virulence comparisons of Aspergillus nidulans mutants are confounded by the inflammatory response of p47phox-/- mice.

NCF1C NCF1B NCF1

1.30e-09339316041040
Pubmed

The p47(phox-/-) mouse model of chronic granulomatous disease has normal granuloma formation and cytokine responses to Mycobacterium avium and Schistosoma mansoni eggs.

NCF1C NCF1B NCF1

1.30e-09339310085000
Pubmed

Oxidants from nicotinamide adenine dinucleotide phosphate oxidase are involved in triggering cell proliferation in the liver due to peroxisome proliferators.

NCF1C NCF1B NCF1

1.30e-09339310987289
Pubmed

Methamphetamine alters occludin expression via NADPH oxidase-induced oxidative insult and intact caveolae.

NCF1C NCF1B NCF1

1.30e-09339321435178
Pubmed

Intermittent hypoxia has organ-specific effects on oxidative stress.

NCF1C NCF1B NCF1

1.30e-09339318703411
Pubmed

Mycobacterial infection induces higher interleukin-1β and dysregulated lung inflammation in mice with defective leukocyte NADPH oxidase.

NCF1C NCF1B NCF1

1.30e-09339329228045
Pubmed

Mycobacteria-induced Gr-1+ subsets from distinct myeloid lineages have opposite effects on T cell expansion.

NCF1C NCF1B NCF1

1.30e-09339317307863
Pubmed

Generation of reactive oxygen species (ROS) is a key factor for stimulation of macrophage proliferation by ceramide 1-phosphate.

NCF1C NCF1B NCF1

1.30e-09339322155727
Pubmed

Ncf1 affects osteoclast formation but is not critical for postmenopausal bone loss.

NCF1C NCF1B NCF1

1.30e-09339327829407
Pubmed

Mechanism of endoplasmic reticulum stress-induced vascular endothelial dysfunction.

NCF1C NCF1B NCF1

1.30e-09339324576409
Pubmed

The presence of p47phox in liver parenchymal cells is a key mediator in the pathogenesis of alcoholic liver steatosis.

NCF1C NCF1B NCF1

1.30e-09339322376231
Pubmed

Leishmania amazonensis amastigotes trigger neutrophil activation but resist neutrophil microbicidal mechanisms.

NCF1C NCF1B NCF1

1.30e-09339323918780
Pubmed

NADPH oxidase NOX2 mediates TLR2/6-dependent release of GM-CSF from endothelial cells.

NCF1C NCF1B NCF1

1.30e-09339328274989
Pubmed

The p47phox deficiency significantly attenuates the pathogenicity of Chlamydia muridarum in the mouse oviduct but not uterine tissues.

NCF1C NCF1B NCF1

1.30e-09339326645958
Pubmed

Role of p47(phox) in vascular oxidative stress and hypertension caused by angiotensin II.

NCF1C NCF1B NCF1

1.30e-09339312364355
Pubmed

NADPH oxidase promotes neutrophil extracellular trap formation in pulmonary aspergillosis.

NCF1C NCF1B NCF1

1.30e-09339324549323
Pubmed

NOX2-Deficient Neutrophils Facilitate Joint Inflammation Through Higher Pro-Inflammatory and Weakened Immune Checkpoint Activities.

NCF1C NCF1B NCF1

1.30e-09339334557202
Pubmed

Reactive Oxygen Species Regulate Both Priming and Established Arthritis, but with Different Mechanisms.

NCF1C NCF1B NCF1

1.30e-09339328467721
Pubmed

P47(phox)-deficient NADPH oxidase defect in neutrophils of diabetic mouse strains, C57BL/6J-m db/db and db/+.

NCF1C NCF1B NCF1

1.30e-09339310670582
Pubmed

NADPH oxidase deficiency regulates Th lineage commitment and modulates autoimmunity.

NCF1C NCF1B NCF1

1.30e-09339320881184
Pubmed

Direct Comparison of a Natural Loss-Of-Function Single Nucleotide Polymorphism with a Targeted Deletion in the Ncf1 Gene Reveals Different Phenotypes.

NCF1C NCF1B NCF1

1.30e-09339326528554
Pubmed

The role of reactive oxygen species in immunopathogenesis of rheumatoid arthritis.

NCF1C NCF1B NCF1

1.30e-09339319052348
Pubmed

Effect of early particulate air pollution exposure on obesity in mice: role of p47phox.

NCF1C NCF1B NCF1

1.30e-09339320864666
Pubmed

Reactive oxygen species delay control of lymphocytic choriomeningitis virus.

NCF1C NCF1B NCF1

1.30e-09339323328631
Pubmed

p47phox-Dependent Oxidant Signalling through ASK1, MKK3/6 and MAPKs in Angiotensin II-Induced Cardiac Hypertrophy and Apoptosis.

NCF1C NCF1B NCF1

1.30e-09339334572995
Pubmed

Acid aspiration-induced lung inflammation and injury are exacerbated in NADPH oxidase-deficient mice.

NCF1C NCF1B NCF1

1.30e-09339317114280
Pubmed

Participation of mitochondrial respiratory complex III in neutrophil activation and lung injury.

NCF1C NCF1B NCF1

1.30e-09339319168575
Pubmed

B-cell epitope spreading and inflammation in a mouse model of arthritis is associated with a deficiency in reactive oxygen species production.

NCF1C NCF1B NCF1

1.30e-09339325989352
Pubmed

NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation.

NCF1C NCF1B NCF1

1.30e-09339319503084
Pubmed

Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase.

NCF1C NCF1B NCF1

1.30e-09339317404617
Pubmed

Critical role of the NAD(P)H oxidase subunit p47phox for left ventricular remodeling/dysfunction and survival after myocardial infarction.

NCF1C NCF1B NCF1

1.30e-09339317332431
Pubmed

Lpp of Escherichia coli K1 inhibits host ROS production to counteract neutrophil-mediated elimination.

NCF1C NCF1B NCF1

1.30e-09339336592568
Pubmed

Genetic requirement of p47phox for superoxide production by murine microglia.

NCF1C NCF1B NCF1

1.30e-09339311156938
Pubmed

Tumour-elicited neutrophils engage mitochondrial metabolism to circumvent nutrient limitations and maintain immune suppression.

NCF1C NCF1B NCF1

1.30e-09339330504842
Pubmed

Genomic structure of the human p47-phox (NCF1) gene.

NCF1C NCF1B NCF1

1.30e-09339310772875
Pubmed

A Feed-Forward Mechanism Involving the NOX Complex and RyR-Mediated Ca2+ Release During Axonal Specification.

NCF1C NCF1B NCF1

1.30e-09339327798190
Pubmed

Endothelium-dependent coronary vasodilatation requires NADPH oxidase-derived reactive oxygen species.

NCF1C NCF1B NCF1

1.30e-09339320702812
Pubmed

Direct interaction of HIV gp120 with neuronal CXCR4 and CCR5 receptors induces cofilin-actin rod pathology via a cellular prion protein- and NOX-dependent mechanism.

NCF1C NCF1B NCF1

1.30e-09339333705493
Pubmed

Inhibition of NADPH oxidase by apocynin attenuates progression of atherosclerosis.

NCF1C NCF1B NCF1

1.30e-09339323965970
Pubmed

Macrophage-derived reactive oxygen species protects against autoimmune priming with a defined polymeric adjuvant.

NCF1C NCF1B NCF1

1.30e-09339326455429
Pubmed

Superoxide generation from Kupffer cells contributes to hepatocarcinogenesis: studies on NADPH oxidase knockout mice.

NCF1C NCF1B NCF1

1.30e-09339315513930
Pubmed

Conditional haploinsufficiency of NCF1 (encoding p47(phox)), a signaling gene with a heterozygous phenotype potentially subject to natural selection.

NCF1C NCF1B NCF1

1.30e-09339315626477
Pubmed

Phosphoinositide 3-kinase regulates the phosphorylation of NADPH oxidase component p47(phox) by controlling cPKC/PKCdelta but not Akt.

NCF1C NCF1B NCF1

1.30e-09339315033459
Pubmed

NCF1 gene and pseudogene pattern: association with parasitic infection and autoimmunity.

NCF1C NCF1B NCF1

1.30e-09339319077231
Pubmed

Neutrophil-derived ROS contribute to oxidative DNA damage induction by quartz particles.

NCF1C NCF1B NCF1

1.30e-09339320828610
Pubmed

p47phox Phox homology domain regulates plasma membrane but not phagosome neutrophil NADPH oxidase activation.

NCF1C NCF1B NCF1

1.30e-09339320817944
Pubmed

Reduction of NADPH-oxidase activity ameliorates the cardiovascular phenotype in a mouse model of Williams-Beuren Syndrome.

NCF1C NCF1B NCF1

1.30e-09339322319452
Pubmed

Early determinants of H2O2-induced endothelial dysfunction.

NCF1C NCF1B NCF1

1.30e-09339316895801
Pubmed

Role and cellular source of nicotinamide adenine dinucleotide phosphate oxidase in hepatic fibrosis.

NCF1C NCF1B NCF1

1.30e-09339320690191
Pubmed

Endosomal acidification and activation of NADPH oxidase isoforms are upstream events in hyperosmolarity-induced hepatocyte apoptosis.

NCF1C NCF1B NCF1

1.30e-09339316772302
Pubmed

Aging increases vulnerability to stress-induced depression via upregulation of NADPH oxidase in mice.

NCF1C NCF1B NCF1

1.30e-09339332504071
Pubmed

Effect of p47phox gene deletion on ROS production and oxygen sensing in mouse carotid body chemoreceptor cells.

NCF1C NCF1B NCF1

1.30e-09339316280459
Pubmed

Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease.

NCF1C NCF1B NCF1

1.30e-09339318185592
Pubmed

NCF1-dependent production of ROS protects against lupus by regulating plasmacytoid dendritic cell development and functions.

NCF1C NCF1B NCF1

1.30e-09339336853827
Pubmed

Prolonged production of reactive oxygen species in response to B cell receptor stimulation promotes B cell activation and proliferation.

NCF1C NCF1B NCF1

1.30e-09339323024271
Pubmed

Ncf1 (p47phox) is essential for direct regulatory T cell mediated suppression of CD4+ effector T cells.

NCF1C NCF1B NCF1

1.30e-09339321253614
Pubmed

Synergistic innate and adaptive immune response to combination immunotherapy with anti-tumor antigen antibodies and extended serum half-life IL-2.

NCF1C NCF1B NCF1

1.30e-09339325873172
Pubmed

Enhanced autoimmunity, arthritis, and encephalomyelitis in mice with a reduced oxidative burst due to a mutation in the Ncf1 gene.

NCF1C NCF1B NCF1

1.30e-09339315310853
Pubmed

Exogenous PP2A inhibitor exacerbates the progression of nonalcoholic fatty liver disease via NOX2-dependent activation of miR21.

NCF1C NCF1B NCF1

1.30e-09339331393787
Pubmed

Vascular effects following homozygous disruption of p47(phox) : An essential component of NADPH oxidase.

NCF1C NCF1B NCF1

1.30e-09339310725280
Pubmed

Ncf1 Governs Immune Niches in the Lung to Mediate Pulmonary Inflammation in Mice.

NCF1C NCF1B NCF1

1.30e-09339334970267
Pubmed

Germ-free mice deficient of reactive oxygen species have increased arthritis susceptibility.

NCF1C NCF1B NCF1

1.30e-09339325689796
Pubmed

Opposing roles of p47phox in basal versus angiotensin II-stimulated alterations in vascular O2- production, vascular tone, and mitogen-activated protein kinase activation.

NCF1C NCF1B NCF1

1.30e-09339314993144
Pubmed

Inhibition of NADPH oxidase promotes alternative and anti-inflammatory microglial activation during neuroinflammation.

NCF1C NCF1B NCF1

1.30e-09339322050439
Pubmed

The vascular NADPH oxidase subunit p47phox is involved in redox-mediated gene expression.

NCF1C NCF1B NCF1

1.30e-09339312031896
Pubmed

NAD(P)H oxidase-derived superoxide mediates hypercholesterolemia-induced leukocyte-endothelial cell adhesion.

NCF1C NCF1B NCF1

1.30e-09339311249873
Pubmed

Ncf1 (p47phox) polymorphism determines oxidative burst and the severity of arthritis in rats and mice.

NCF1C NCF1B NCF1

1.30e-09339315936744
Pubmed

NADPH oxidase modulates myocardial Akt, ERK1/2 activation, and angiogenesis after hypoxia-reoxygenation.

NCF1C NCF1B NCF1

1.30e-09339317220182
Pubmed

NADPH oxidase p47phox siRNA attenuates adventitial fibroblasts proliferation and migration in apoE(-/-) mouse.

NCF1C NCF1B NCF1

1.30e-09339325628043
Pubmed

The p47phox mouse knock-out model of chronic granulomatous disease.

NCF1C NCF1B NCF1

1.30e-0933937650482
Pubmed

Disseminated trichosporonosis in a murine model of chronic granulomatous disease.

NCF1C NCF1B NCF1

1.30e-09339312868577
Pubmed

Mechanism of endothelial cell NADPH oxidase activation by angiotensin II. Role of the p47phox subunit.

NCF1C NCF1B NCF1

1.30e-09339312560337
Pubmed

NADPH oxidase mediates striatal neuronal injury after transient global cerebral ischemia.

NCF1C NCF1B NCF1

1.30e-09339320859296
Pubmed

Inhibition of endothelial Nox2 activation by LMH001 protects mice from angiotensin II-induced vascular oxidative stress, hypertension and aortic aneurysm.

NCF1C NCF1B NCF1

1.30e-09339335276443
Cytoband8q22

TP53INP1 UBR5

7.33e-05153928q22
Cytoband7q11.23

NCF1C NCF1B NCF1

7.91e-05973937q11.23
CytobandEnsembl 112 genes in cytogenetic band chr7q11

NCF1C NCF1B NCF1

1.59e-03271393chr7q11
Cytoband16q22.1

SLC7A6OS DDX28

3.98e-0311039216q22.1
GeneFamilyAnoctamins

ANO9 ANO8

8.20e-0510252865
GeneFamilyPDZ domain containing

PARD6B ARHGAP21 PPP1R9A

1.17e-031522531220
GeneFamilySterile alpha motif domain containing

PPP1R9A EPHA1

6.53e-0388252760
CoexpressionGAVIN_PDE3B_TARGETS

NCF1C NCF1B NCF1

6.85e-0625393MM726
CoexpressionBOYLAN_MULTIPLE_MYELOMA_D_DN

NCF1C NCF1B ARHGAP21 NCF1

1.16e-0594394MM787
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CXCR5 TP53INP1 NCF1C NCF1B NCF1

7.23e-07194395ff661419b697aef51a53fdeac8d37d870d65f491
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)|356C / Donor, Lineage, Cell class and subclass (all cells)

SYNPO TCERG1L CILP AEBP1

1.56e-0517339475e26a65071b0d2f30ed0b2aa9859c488f5cf362
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|356C / Donor, Lineage, Cell class and subclass (all cells)

SYNPO TCERG1L CILP AEBP1

1.56e-0517339426e2e674f5d312fa8f61c11b553dc6101f063b16
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-plasmacytoid_dendritic_cell|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TCERG1L AEBP1 DTX4 CUEDC1

1.79e-05179394124da6f882968dc0d05f3edd8f3b4d61617cc214
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TCERG1L AEBP1 DTX4 CUEDC1

1.79e-05179394edc5ef693dc4e7ea70717b77fb908fc784dce3a2
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IGFBP6 CILP AEBP1 ANO8

1.99e-05184394d754c3de621429b220ae4ac426cdfc619e848462
ToppCellSmart-seq2-spleen_(Smart-seq2)|Smart-seq2 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CXCR5 UBE2J1 NCF1C NCF1

2.21e-05189394b0244a9d1b5c8ad4708750b691184f3491b13900
ToppCellB_cell_maturation|World / Lineage and Cell class

CXCR5 TP53INP1 AEBP1 NCF1

2.26e-05190394301782283d0c604fb3b428a8ddf1f7cd8e63a90b
ToppCellBLOOD--(2)_Memory_B_cells| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CXCR5 UBE2J1 SYNPO NCF1

2.35e-051923949c3a4699f05f1a757d6e37d9f15675e970584cca
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CXCR5 UBE2J1 NCF1C NCF1

2.40e-05193394325859399411d0e66a78a385dffa886df9af3198
ToppCell10x5'v1-week_14-16-Lymphocytic_B-B_lineage-naive_B_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CXCR5 UBE2J1 AEBP1 NCF1

2.45e-051943944a4cc61193344bb151439f63d0584abddde47cf0
ToppCell10x5'-bone_marrow-Lymphocytic_B|bone_marrow / Manually curated celltypes from each tissue

CXCR5 TP53INP1 AEBP1 NCF1

2.50e-05195394bcbf0305ca9337a6f3021178dbb47a7fbf1030a4
ToppCellPBMC-Mild-Lymphocyte-B-B_cell|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CXCR5 SYNPO TP53INP1 NCF1

2.60e-05197394f7a8440d2b8b17d9726c6fe3dd383effbfebab13
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TP53INP1 NCF1C NCF1B NCF1

2.60e-05197394fa3cc33c975648172feabb485c3bdd087f1f8ea7
ToppCellproximal-Hematologic-B_cell|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CXCR5 NCF1C NCF1B NCF1

2.60e-05197394735b5026d28cd3677947ae8e462f6fd640cf9c9b
ToppCellBronchial-NucSeq-Immune_Lymphocytic-B|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CXCR5 UBE2J1 TP53INP1 NCF1

2.60e-051973940f489d26e4013d1b5a90559856ed2de32a0bb772
ToppCellproximal-Hematologic-B_cell-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CXCR5 NCF1C NCF1B NCF1

2.60e-0519739408b3f2e3933242b9fa93998cfce3d094a3db833e
ToppCellproximal-3-Hematologic-B_cell|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CXCR5 NCF1C NCF1B NCF1

2.60e-0519739481ba0eb2222e83b4ba2db3228dc04c390c2dbc63
ToppCellmild-B_memory|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CXCR5 UBE2J1 SYNPO TP53INP1

2.71e-05199394025bb65629d9e20c374e8f1ba08c36d1bb569190
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NCF1C NCF1B GYS1 NCF1

2.76e-05200394851c57187db8bc91a393655bca5f13e787a723d4
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Dedifferentiated_Liposarcoma-6|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

NCF1C NCF1B NCF1

1.95e-041293936071762027460b97c6642c58d06992f2b2703186
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|367C / Donor, Lineage, Cell class and subclass (all cells)

ANO9 TCERG1L EPHA1

2.04e-04131393cc5b5afab8622e98f673fa116a226d930c295327
ToppCelltumor_Lung-T/NK_cells-CD8_low_T|T/NK_cells / Location, Cell class and cell subclass

CXCR5 FRMD4A EPHA1

2.59e-04142393eaf08a0dbacc9ebbd54e377922e76d8ba854dcb8
ToppCellE18.5-samps-Mesenchymal-Pericyte-pericyte_D|E18.5-samps / Age Group, Lineage, Cell class and subclass

SYNPO AEBP1 DTX4

2.98e-04149393dcf68eb25733b5db2893728fe4dca5c7267eb58c
ToppCellHealthy_donor-B_cell|World / disease group, cell group and cell class (v2)

CXCR5 TRPM3 PPP1R9A

3.04e-04150393a2dfed562de7f58f902b547acec5a13853c80c4c
ToppCell3'_v3-blood-Lymphocytic_T_CD4-Tfh|blood / Manually curated celltypes from each tissue

CXCR5 FLT4 TP53INP1

3.28e-041543935ff380205fa7ab97ba21f6512bc9e14c0fb320b6
ToppCell367C-Lymphocytic-NK_cells-NK_cell_D2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

SYNPO LSM14B NCF1

3.41e-041563930b3630fd4479291599e1674e87eba6f93877ac3a
ToppCell3'_v3-bone_marrow-Lymphocytic_B-Pro-B|bone_marrow / Manually curated celltypes from each tissue

TP53INP1 ARHGEF17 AEBP1

3.41e-04156393b093dbba6662e4fffc8aa577587b77f64ac44b56
ToppCellPND28-Immune-Immune_Myeloid-Granulocytic-Basophil|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PARD6B PHLDB3 NCF1

3.47e-041573938c42af7aa1f1b6f4fe2f8d00a8b4a800f121e804
ToppCellPND28-Immune-Immune_Myeloid-Granulocytic|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PARD6B PHLDB3 NCF1

3.47e-04157393ee1be3c756b72fceac6b4ccb416dd4bd031a2193
ToppCellPND28-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PARD6B PHLDB3 NCF1

3.47e-04157393008f938a338f43c3251dcac574f1b4f689926c71
ToppCellfacs-Lung-24m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DDX28 PPP1R9A EPHA1

3.60e-04159393999f30c7273ed77b34537621bcfcc7fc30121138
ToppCell10x5'-Lung-Lymphocytic_B-ABC_aged-B_memory|Lung / Manually curated celltypes from each tissue

CXCR5 SYNPO AEBP1

3.60e-04159393d3202ddc291b8686dbe67690df13c7daffec2199
ToppCellControl-Stromal-Pericyte|Stromal / Disease state, Lineage and Cell class

PARD6B ARHGEF17 PPP1R9A

3.60e-041593936f50c381cd8a26a5a90bf0ce909713cea96910d7
ToppCell5'-Adult-LymphNode-Hematopoietic-Plasma_cells-IgA_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

UBE2J1 TP53INP1 NCF1

3.67e-04160393e44b3c74c76b4632ada7f5bd6d09434b02d79743
ToppCelldroplet-Fat-Scat-21m-Lymphocytic-B_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCR5 TCERG1L SAPCD2

3.74e-04161393e52735f955f0a53da5cbe5a2d77a00484e5109b3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FRMD4A ARHGEF17 TRPM3

3.74e-041613931b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCellkidney_cells-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

UBE2J1 TP53INP1 NCF1C

3.81e-04162393ee6f05620f4f4ebbebd5b098afc7c20876e3d21f
ToppCellkidney_cells-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

UBE2J1 TP53INP1 NCF1C

3.81e-041623939e72d468fcdd0d27b517a9e36efb35d4617a88f9
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells-DZ_GC_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

UBE2J1 NCF1 DNMT1

3.81e-041623933e15b3e97a2ade86d0cb0ab15fccb9a2e2e27dd4
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD8-Tem/emra_CD8|GI_small-bowel / Manually curated celltypes from each tissue

ARHGEF17 CTSG SLC30A10

3.88e-041633931a8c79903ed416f286ebe8a9922233affbc55d82
ToppCellLPS-antiTNF-Endothelial-Mes-Like-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLT4 TCERG1L TP53INP1

4.09e-041663933b750d4023a0a09d86113aae5a97d84391f7b482
ToppCellhealthy_donor-Lymphocytic-Plasma_cell-IgM_Plasmablast|healthy_donor / Disease condition, Lineage, Cell class and subclass

UBE2J1 TP53INP1 CTSG

4.09e-041663932b7b580bec8d9467b0deaf97098065f72dbf2a4f
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANO9 IGFBP6 AEBP1

4.16e-04167393c042d6cdddd0e1ddef1e3ac6f4fe23151127b0f2
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANO9 IGFBP6 AEBP1

4.16e-041673937abc785e688a384672d7fb5a62d32538fe7e5a51
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANO9 IGFBP6 AEBP1

4.16e-04167393d50311b1f66f143bae4c4cf50e2e9b13c85d6920
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANO9 IGFBP6 AEBP1

4.16e-04167393351f8de1fbdf742ac74f9099b254d515ab539bb2
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8|TCGA-Thryoid / Sample_Type by Project: Shred V9

SYNPO TCERG1L ARHGEF17

4.23e-0416839300646601548b0fee42ae16bfa5e93603bc7c5129
ToppCellBronchial_Brush-Immune-B_cells|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

CXCR5 AEBP1 NCF1

4.31e-04169393dc388f660f69e37e517bf3243daf071ab138ee6e
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|390C / Donor, Lineage, Cell class and subclass (all cells)

ANO9 TP53INP1 EPHA1

4.31e-04169393cfc9ff103d13a2d5eacc457e800f53fdd29f7738
ToppCelldroplet-Liver-HEPATOCYTES-1m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCR5 TSEN54 ARHGAP21

4.31e-04169393d721dbb317a88113b4f76688111908d00f23e899
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IGFBP6 CILP AEBP1

4.31e-04169393031465190cd3623a25ef2b868daab8d932c8ff08
ToppCellChildren_(3_yrs)-Immune-B_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CXCR5 TP53INP1 NCF1

4.38e-04170393e421f9eedf74baffda1d03707a710ece4b777f29
ToppCell3'_v3-Lung-Lymphocytic_B-Memory_B_cells|Lung / Manually curated celltypes from each tissue

CXCR5 SYNPO TP53INP1

4.46e-041713939ecef653f6916572bf5fbee5aea6c577d04e96ba
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IGFBP6 CILP AEBP1

4.46e-0417139315cb4670ff4234ac46aea8a5911138d6913c4482
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHLDB3 FLT4 SLC30A10

4.53e-04172393b3c4adccc34bb9e4e78e40f4e2e23736c347cc75
ToppCellP07-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ANO9 IGFBP6 AEBP1

4.53e-041723939a256db817c1af1802203cc88a55d608fb328c63
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FRMD4A ARHGEF17 TRPM3

4.53e-0417239308a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PHLDB3 CTSG NCF1

4.53e-04172393c05af6e559f6af0fb15cefa03ffa1413e98a1a4a
ToppCellfacs-Lung-Endomucin-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHLDB3 FLT4 SLC30A10

4.53e-041723932f1673fcb2356684d60871debb0f159aec553a1c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FRMD4A ARHGEF17 TRPM3

4.53e-04172393553701349444eb366df3c11f54bb093434f153c6
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ANO9 TCERG1L EPHA1

4.53e-04172393da959c1abadafd79b7a0088a25eb8ef8efa3a0c2
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Basophil|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PHLDB3 CTSG NCF1

4.53e-04172393953b05f776348cff784e79c93df65841939d880f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO AEBP1 SAPCD2

4.61e-041733933001dd39244ef0a5a475d569a78f4ae427a55db6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO AEBP1 SAPCD2

4.61e-04173393c88883fb2a33e21d4201aa393674aa3f2ad780c9
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANO9 IGFBP6 AEBP1

4.61e-0417339330d67738633493d47f06ae452424382f069b6c0a
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IGFBP6 CILP AEBP1

4.69e-041743939c916af5eebd932f67dc9117e1d26ff194a2ff2c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IGFBP6 CILP AEBP1

4.69e-04174393bc71521f44a5fe013af42b06b5d1bd2446ecf3b5
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANO9 IGFBP6 AEBP1

4.69e-04174393a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARD6B F2 CUEDC1

4.77e-041753931b35acece23712ab7e3f92d9d68266efd38b3ef5
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHLDB3 SAPCD2 EPHA1

4.77e-0417539331f0fb2e47e357dbf9c15436b7df85b3c370ded7
ToppCell5'-Adult-LymphNode-Hematopoietic-Plasma_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

UBE2J1 TP53INP1 NCF1

4.77e-041753936a093c74a6f3daeff07759d6eec542fc5c709149
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FRMD4A NCF1 EPHA1

4.77e-041753936374ab186d7ccf7f6dfb858267edba8962789e15
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARD6B F2 CUEDC1

4.77e-04175393a9f88054e2c28d604c65ed785f63021aadb7f4c8
ToppCellP15-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PHLDB3 FLT4 AEBP1

4.77e-0417539384d252f3e432231687613299bbea14978bb4b06b
ToppCellP15-Endothelial-lymphatic_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PHLDB3 FLT4 AEBP1

4.77e-04175393a00c6fa9b33640710dd05a3799031147196f0986
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l2|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CILP CTSG DDX28

4.85e-041763931510cdfcfb46ce1196a1220c07fb5f3986c81b78
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANO9 IGFBP6 AEBP1

4.85e-041763938e7f38de8bf68077e2138f4d06c1f55b0fd096cc
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|343B / Donor, Lineage, Cell class and subclass (all cells)

TCERG1L IGFBP6 AEBP1

4.85e-041763932e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANO9 IGFBP6 AEBP1

4.85e-04176393ed575330a08a6748ea4b28433292c8cfd157d444
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|343B / Donor, Lineage, Cell class and subclass (all cells)

TCERG1L IGFBP6 AEBP1

4.85e-04176393f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCellLPS-IL1RA+antiTNF|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRPM3 ARHGAP21 PPP1R9A

4.93e-04177393b7fee75de7e96924af488a5baa2334711889ae7c
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANO9 FLT4 FGF17

4.93e-0417739376f5df101c693e5fa61554244d877fc8169ee66f
ToppCellCOVID-19_Moderate-B_intermediate|COVID-19_Moderate / disease group, cell group and cell class

CXCR5 SYNPO NCF1

4.93e-0417739368e3d12a0c048a2d0f1b9680c7338a35855bba30
ToppCelldroplet-Fat-SCAT-30m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGFBP6 CILP AEBP1

5.01e-041783935cf12927f0756c4d8a289fe4308d736382e6212e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

UBE2J1 TP53INP1 NCF1

5.01e-04178393f815bc76f98aaea2d9058173b02b6f36e45283ce
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

UBE2J1 TP53INP1 NCF1

5.01e-04178393a0334764e865fea652c54b94bbc3b173f7cbc9fc
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CXCR5 UBE2J1 NCF1

5.01e-04178393107dae8b00c4257697a63700e72bb434cdb8406f
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ANO9 IGFBP6 AEBP1

5.01e-041783931e05bc26591fea16e29bcfc5f538dda1dc427f05
ToppCellChildren_(3_yrs)-Immune-B_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CXCR5 UBE2J1 NCF1

5.09e-0417939331411780f1a44bf2d102f288416e97eacec4b6b6
ToppCellControl-Stromal-SMC|Control / Disease state, Lineage and Cell class

IGFBP6 ARHGEF17 AEBP1

5.09e-041793931378051bc62009eec2dbecf3d5d89baedbeb84eb
ToppCellCOVID-19_Moderate-B_memory|World / disease group, cell group and cell class

CXCR5 SYNPO SLC30A10

5.18e-041803932f37187b866edb56410c2334b72713f2248dc335
ToppCelldroplet-Liver-LIVER-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGFBP6 AEBP1 CTSG

5.18e-041803933d95232b5785c705f41e01e3ffe0fa8dce1ff0a7
ToppCellfacs-Kidney-nan-24m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGFBP6 AEBP1 CTSG

5.18e-04180393f9f8245cbcdea18c15e2976c85b72c6807309787
ToppCellBAL-Severe-Lymphocyte-B-B_cell-B_cell-B_activate-7|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CXCR5 PARD6B PPP1R9A

5.18e-041803939f4bbaf6435c23e3e552ae22be8ea7884314192d
ToppCellBAL-Severe-Lymphocyte-B-B_cell-B_cell|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CXCR5 PARD6B PPP1R9A

5.18e-04180393b465f2f8b0e9a2034a4f1272bb00c77439164dbf
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

IGFBP6 CILP AEBP1

5.18e-041803939adebde5f4ca6dcb90e9113622862e14298465ac
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells-Cycling_plasma_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CXCR5 UBE2J1 SAPCD2

5.18e-04180393ce2fc270f9d9110c2544083f61936b0b7d3b7eb3
ToppCelldroplet-Liver-LIVER-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGFBP6 AEBP1 CTSG

5.18e-0418039347e345359064dc8ceec982b062e47802e728b43f
ToppCellBAL-Severe-Lymphocyte-B-B_cell|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CXCR5 PARD6B PPP1R9A

5.18e-04180393c3c72531af5b9f7a7416727fe609dab5180e03b6
Diseasechronic granulomatous disease (implicated_via_orthology)

NCF1C NCF1B NCF1

1.81e-085373DOID:3265 (implicated_via_orthology)
Diseaserheumatoid arthritis (implicated_via_orthology)

NCF1C NCF1B NCF1

3.96e-0712373DOID:7148 (implicated_via_orthology)
DiseaseClear-cell metastatic renal cell carcinoma

FLT4 DNMT1

9.17e-064372C2931852
DiseaseCarcinoma, Pancreatic Ductal

DTX4 DNMT1

4.15e-0424372C0887833
Diseaseserum gamma-glutamyl transferase measurement

PARD6B TP53INP1 LSM14B ARHGAP21 EPHA1 DNMT1

8.89e-04914376EFO_0004532
DiseaseHuntington's disease (is_marker_for)

F2 PPP1R9A

2.03e-0353372DOID:12858 (is_marker_for)
Diseasesystemic scleroderma (is_marker_for)

FLT4 F2

2.03e-0353372DOID:418 (is_marker_for)
Diseasehair morphology measurement

FRMD4A RPTOR

2.10e-0354372EFO_0007821

Protein segments in the cluster

PeptideGeneStartEntry
LVFRSRRAQRQRQQR

EPHA1

566

P21709
VVHRLRQAQRRPQRQ

CXCR5

241

P32302
RQAQRRPQRQKAVRV

CXCR5

246

P32302
TLGQRRAQARRQTIR

DNMT1

591

P26358
MTPQQRRLQQRRLQH

AEBP1

1011

Q8IUX7
QRHTQRDPRQARQQQ

ANO9

41

A1A5B4
GQINRQTQRQRRVRR

DTX4

141

Q9Y2E6
RQAQHRYQQQQRRRR

ANO8

891

Q9HCE9
QGRPRQASRSRQNQR

FGF17

156

O60258
QRNRGNRLQDNRQFR

RAMAC

51

Q9BTL3
VRPANQRNNVVRNSR

PARD6B

246

Q9BYG5
RLRRPQQQQERAQRP

ARHGEF17

196

Q96PE2
RGRQQREQEQRRLSQ

PHLDB3

171

Q6NSJ2
QVNDENRRPQRRRSG

LSM14B

211

Q9BX40
NRRTRNRSRGQNRPT

LSM14B

226

Q9BX40
RNSVRFLQQRRRQAR

NCF1

326

P14598
QELNNSRPARQVRRL

CUEDC1

31

Q9NWM3
NRRNNRNKRNRQNRS

HNRNPUL2

641

Q1KMD3
ALQRQLEQRQSRRRN

DDX28

41

Q9NUL7
RRNSVRFLQQRRRQA

NCF1B

326

A6NI72
RRNSVRFLQQRRRQA

NCF1C

301

A8MVU1
PSKARQRQRQRQRAA

FRMD4A

776

Q9P2Q2
LLQLSRRVRRNRNVN

CTSG

111

P08311
QQSRRQRIIQRNRTE

GYS1

576

P13807
TARPQDVNRRDQQRN

IGFBP6

126

P24592
QRRQVQRSQRRAPHL

TSEN54

386

Q7Z6J9
SNSRGVQLFNRRRQR

SYNPO

166

Q8N3V7
RFLRNSRVRRQAQQV

RPTOR

991

Q8N122
VQGRVPSRRQQRASR

CILP

1146

O75339
LRPSRDSQQRVRRNL

SLC7A6OS

76

Q96CW6
RFQRRRRQLQQQQPR

TCERG1L

6

Q5VWI1
RRQLQQQQPRRRQPL

TCERG1L

11

Q5VWI1
RGRSRRLQQRQQLAE

SLC30A10

146

Q6XR72
QRVQERQRRLGQSRA

SAPCD2

261

Q86UD0
DRQRNTASLRNPFQR

TRPM3

1686

Q9HCF6
RQPLNRNSLRRQNLT

TP53INP1

201

Q96A56
QRSLRRRQQQDLMPQ

FLT4

471

P35916
SPRQRRAQQQSQRRL

UBE2J1

251

Q9Y385
PQQARSLLQRVRRAN

F2

31

P00734
NQVVPNRTTLQGRRR

ARHGAP21

426

Q5T5U3
RNPQQRRISQSQPVR

UBR5

1541

O95071
RAQLSVKNRRQRPSR

PPP1R9A

886

Q9ULJ8