| GeneOntologyMolecularFunction | RNA polymerase II cis-regulatory region sequence-specific DNA binding | ZNF729 ZNF141 ZNF527 ZNF573 ZNF486 ZNF695 ZNF354A ZNF273 ZNF254 ZNF485 ZNF195 ZFP28 ZNF736 ZNF519 ZNF354B ZNF251 ZNF595 ZNF3 ZNF677 ZNF514 ZNF610 ZNF713 ZNF732 ZNF718 ZNF257 ZNF764 ZNF253 ZNF92 ZNF66 ZNF611 ZNF816 ZNF737 ZNF506 ZNF534 ZNF727 ZNF479 ZNF808 ZNF578 ZNF766 ZNF701 ZNF860 ZNF85 ZNF723 ZNF30 ZNF90 ZNF91 ZNF98 ZNF583 ZNF445 | 2.90e-31 | 1244 | 105 | 49 | GO:0000978 |
| GeneOntologyMolecularFunction | DNA-binding transcription factor activity, RNA polymerase II-specific | ZNF729 ZNF141 ZNF527 ZNF573 ZNF486 ZNF695 ZNF354A ZNF273 ZNF559 ZNF254 ZNF485 ZNF195 ZFP28 ZNF736 ZNF519 ZNF354B ZNF251 ZNF595 ZNF3 ZNF677 ZNF514 ZNF610 ZNF713 ZNF732 ZNF718 ZNF257 ZNF764 ZNF253 ZNF92 ZNF66 ZNF611 ZNF816 ZNF737 ZNF506 ZNF534 ZNF727 ZNF479 ZNF808 ZNF578 ZNF766 ZNF701 ZNF860 ZNF85 ZNF723 ZNF30 ZFP69B ZNF90 ZNF91 ZNF98 ZNF583 ZNF445 | 6.42e-31 | 1412 | 105 | 51 | GO:0000981 |
| GeneOntologyMolecularFunction | cis-regulatory region sequence-specific DNA binding | ZNF729 ZNF141 ZNF527 ZNF573 ZNF486 ZNF695 ZNF354A ZNF273 ZNF254 ZNF485 ZNF195 ZFP28 ZNF736 ZNF519 ZNF354B ZNF251 ZNF595 ZNF3 ZNF677 ZNF514 ZNF610 ZNF713 ZNF732 ZNF718 ZNF257 ZNF764 ZNF253 ZNF92 ZNF66 ZNF611 ZNF816 ZNF737 ZNF506 ZNF534 ZNF727 ZNF479 ZNF808 ZNF578 ZNF766 ZNF701 ZNF860 ZNF85 ZNF723 ZNF30 ZNF90 ZNF91 ZNF98 ZNF583 ZNF445 | 7.84e-31 | 1271 | 105 | 49 | GO:0000987 |
| GeneOntologyMolecularFunction | RNA polymerase II transcription regulatory region sequence-specific DNA binding | ZNF729 ZNF141 ZNF527 ZNF573 ZNF486 ZNF695 ZNF354A ZNF273 ZNF559 ZNF254 ZNF485 ZNF195 ZFP28 ZNF736 ZNF519 ZNF354B ZNF251 ZNF595 ZNF3 ZNF677 ZNF514 ZNF610 ZNF713 ZNF732 ZNF718 ZNF257 ZNF764 ZNF253 ZNF92 ZNF66 ZNF611 ZNF816 ZNF737 ZNF506 ZNF534 ZNF727 ZNF479 ZNF808 ZNF578 ZNF766 ZNF701 ZNF860 ZNF85 ZNF723 ZNF30 ZFP69B ZNF90 ZNF91 ZNF98 ZNF583 ZNF445 | 3.07e-30 | 1459 | 105 | 51 | GO:0000977 |
| GeneOntologyMolecularFunction | DNA-binding transcription activator activity, RNA polymerase II-specific | ZNF729 ZNF695 ZNF485 ZNF736 ZNF519 ZNF3 ZNF727 ZNF808 ZNF85 ZNF91 ZNF445 | 1.76e-04 | 560 | 105 | 11 | GO:0001228 |
| GeneOntologyMolecularFunction | DNA-binding transcription activator activity | ZNF729 ZNF695 ZNF485 ZNF736 ZNF519 ZNF3 ZNF727 ZNF808 ZNF85 ZNF91 ZNF445 | 1.93e-04 | 566 | 105 | 11 | GO:0001216 |
| GeneOntologyMolecularFunction | clathrin light chain binding | CLTCL1 CLTC | 5.65e-04 | 7 | 105 | 2 | GO:0032051 |
| MousePheno | decreased eosinophil cell number | ZNF729 ZNF695 ZNF736 ZNF727 ZNF85 ZNF91 | 9.00e-07 | 84 | 55 | 6 | MP:0005012 |
| MousePheno | anisopoikilocytosis | HEPH ADD2 VPS13A | 3.77e-05 | 17 | 55 | 3 | MP:0002641 |
| MousePheno | abnormal eosinophil cell number | ZNF729 ZNF695 COL17A1 ZNF736 ZNF727 ZNF85 ZNF91 | 5.95e-05 | 255 | 55 | 7 | MP:0002602 |
| MousePheno | abnormal eosinophil morphology | ZNF729 ZNF695 COL17A1 ZNF736 ZNF727 ZNF85 ZNF91 | 6.73e-05 | 260 | 55 | 7 | MP:0005061 |
| Domain | KRAB | ZNF729 ZNF141 ZNF527 ZNF573 ZNF486 ZNF695 ZNF354A ZNF273 ZNF559 ZNF254 ZNF485 ZIM2 ZNF195 ZFP28 ZNF736 ZNF519 ZNF354B ZNF251 ZNF595 ZNF3 ZNF677 ZNF514 ZNF610 ZNF713 ZNF732 ZNF718 ZNF257 ZNF764 ZNF253 ZNF92 ZNF611 ZNF816 ZNF737 ZNF506 ZNF534 ZNF727 ZNF479 ZNF808 ZNF578 ZNF766 ZNF701 ZNF860 ZNF85 ZNF30 ZFP69B ZNF90 ZNF91 ZNF98 ZNF583 ZNF445 | 2.40e-58 | 358 | 104 | 50 | PS50805 |
| Domain | KRAB | ZNF729 ZNF141 ZNF527 ZNF573 ZNF486 ZNF695 ZNF354A ZNF273 ZNF559 ZNF254 ZNF485 ZIM2 ZNF195 ZFP28 ZNF736 ZNF519 ZNF354B ZNF251 ZNF595 ZNF3 ZNF677 ZNF514 ZNF610 ZNF713 ZNF732 ZNF718 ZNF257 ZNF764 ZNF253 ZNF92 ZNF611 ZNF816 ZNF737 ZNF506 ZNF534 ZNF727 ZNF479 ZNF808 ZNF578 ZNF766 ZNF701 ZNF860 ZNF85 ZNF30 ZFP69B ZNF90 ZNF91 ZNF98 ZNF583 ZNF445 | 2.40e-58 | 358 | 104 | 50 | PF01352 |
| Domain | KRAB | ZNF729 ZNF141 ZNF527 ZNF573 ZNF486 ZNF695 ZNF354A ZNF273 ZNF559 ZNF254 ZNF485 ZIM2 ZNF195 ZFP28 ZNF736 ZNF519 ZNF354B ZNF251 ZNF595 ZNF3 ZNF677 ZNF514 ZNF610 ZNF713 ZNF732 ZNF718 ZNF257 ZNF764 ZNF253 ZNF92 ZNF611 ZNF816 ZNF737 ZNF506 ZNF534 ZNF727 ZNF479 ZNF808 ZNF578 ZNF766 ZNF701 ZNF860 ZNF85 ZNF30 ZFP69B ZNF90 ZNF91 ZNF98 ZNF583 ZNF445 | 1.18e-57 | 369 | 104 | 50 | SM00349 |
| Domain | KRAB | ZNF729 ZNF141 ZNF527 ZNF573 ZNF486 ZNF695 ZNF354A ZNF273 ZNF559 ZNF254 ZNF485 ZIM2 ZNF195 ZFP28 ZNF736 ZNF519 ZNF354B ZNF251 ZNF595 ZNF3 ZNF677 ZNF514 ZNF610 ZNF713 ZNF732 ZNF718 ZNF257 ZNF764 ZNF253 ZNF92 ZNF611 ZNF816 ZNF737 ZNF506 ZNF534 ZNF727 ZNF479 ZNF808 ZNF578 ZNF766 ZNF701 ZNF860 ZNF85 ZNF30 ZFP69B ZNF90 ZNF91 ZNF98 ZNF583 ZNF445 | 1.36e-57 | 370 | 104 | 50 | IPR001909 |
| Domain | zf-C2H2 | ZNF729 ZNF141 ZNF527 ZNF573 ZNF486 ZNF695 ZNF354A ZNF273 ZNF559 ZNF254 ZNF485 ZIM2 ZNF195 ZFP28 ZNF736 ZNF519 ZNF354B ZNF251 ZNF595 ZNF3 ZNF677 ZNF514 ZNF610 ZNF713 ZNF732 ZNF718 ZNF257 ZNF764 ZNF253 ZNF92 ZNF611 ZNF816 ZNF737 ZNF506 ZNF534 ZNF727 ZNF479 ZNF808 ZNF578 ZNF766 ZNF701 ZNF860 ZNF85 ZNF30 ZFP69B ZNF90 ZNF91 ZNF98 ZNF583 ZNF445 | 1.18e-43 | 693 | 104 | 50 | PF00096 |
| Domain | Znf_C2H2/integrase_DNA-bd | ZNF729 ZNF141 ZNF527 ZNF573 ZNF486 ZNF695 ZNF354A ZNF273 ZNF559 ZNF254 ZNF485 ZIM2 ZNF195 ZFP28 ZNF736 ZNF519 ZNF354B ZNF251 ZNF3 ZNF677 ZNF514 ZNF610 ZNF713 ZNF732 ZNF718 ZNF257 ZNF764 ZNF253 ZNF92 ZNF611 ZNF816 ZNF737 ZNF506 ZNF534 ZNF727 ZNF479 ZNF808 ZNF578 ZNF766 ZNF701 ZNF860 ZNF85 ZNF30 ZFP69B ZNF90 ZNF91 ZNF98 ZNF583 ZNF445 | 3.20e-42 | 694 | 104 | 49 | IPR013087 |
| Domain | - | ZNF729 ZNF141 ZNF527 ZNF573 ZNF486 ZNF695 ZNF354A ZNF273 ZNF559 ZNF254 ZNF485 ZIM2 ZNF195 ZFP28 ZNF736 ZNF519 ZNF354B ZNF251 ZNF3 ZNF677 ZNF514 ZNF610 ZNF732 ZNF718 ZNF257 ZNF764 ZNF253 ZNF92 ZNF611 ZNF816 ZNF737 ZNF506 ZNF534 ZNF727 ZNF479 ZNF808 ZNF578 ZNF766 ZNF701 ZNF860 ZNF85 ZNF30 ZFP69B ZNF90 ZNF91 ZNF98 ZNF583 ZNF445 | 2.75e-41 | 679 | 104 | 48 | 3.30.160.60 |
| Domain | ZINC_FINGER_C2H2_2 | ZNF729 ZNF141 ZNF527 ZNF573 ZNF486 ZNF695 ZNF354A ZNF273 ZNF559 ZNF254 ZNF485 ZIM2 ZNF195 ZFP28 ZNF736 ZNF519 ZNF354B ZNF251 ZNF595 ZNF3 ZNF677 ZNF514 ZNF610 ZNF713 ZNF732 ZNF718 ZNF257 ZNF764 ZNF253 ZNF92 ZNF611 ZNF816 ZNF737 ZNF506 ZNF534 ZNF727 ZNF479 ZNF808 ZNF578 ZNF766 ZNF701 ZNF860 ZNF85 ZNF30 ZFP69B ZNF90 ZNF91 ZNF98 ZNF583 ZNF445 | 3.02e-41 | 775 | 104 | 50 | PS50157 |
| Domain | ZINC_FINGER_C2H2_1 | ZNF729 ZNF141 ZNF527 ZNF573 ZNF486 ZNF695 ZNF354A ZNF273 ZNF559 ZNF254 ZNF485 ZIM2 ZNF195 ZFP28 ZNF736 ZNF519 ZNF354B ZNF251 ZNF595 ZNF3 ZNF677 ZNF514 ZNF610 ZNF713 ZNF732 ZNF718 ZNF257 ZNF764 ZNF253 ZNF92 ZNF611 ZNF816 ZNF737 ZNF506 ZNF534 ZNF727 ZNF479 ZNF808 ZNF578 ZNF766 ZNF701 ZNF860 ZNF85 ZNF30 ZFP69B ZNF90 ZNF91 ZNF98 ZNF583 ZNF445 | 3.43e-41 | 777 | 104 | 50 | PS00028 |
| Domain | Znf_C2H2 | ZNF729 ZNF141 ZNF527 ZNF573 ZNF486 ZNF695 ZNF354A ZNF273 ZNF559 ZNF254 ZNF485 ZIM2 ZNF195 ZFP28 ZNF736 ZNF519 ZNF354B ZNF251 ZNF595 ZNF3 ZNF677 ZNF514 ZNF610 ZNF713 ZNF732 ZNF718 ZNF257 ZNF764 ZNF253 ZNF92 ZNF611 ZNF816 ZNF737 ZNF506 ZNF534 ZNF727 ZNF479 ZNF808 ZNF578 ZNF766 ZNF701 ZNF860 ZNF85 ZNF30 ZFP69B ZNF90 ZNF91 ZNF98 ZNF583 ZNF445 | 1.96e-40 | 805 | 104 | 50 | IPR007087 |
| Domain | ZnF_C2H2 | ZNF729 ZNF141 ZNF527 ZNF573 ZNF486 ZNF695 ZNF354A ZNF273 ZNF559 ZNF254 ZNF485 ZIM2 ZNF195 ZFP28 ZNF736 ZNF519 ZNF354B ZNF251 ZNF595 ZNF3 ZNF677 ZNF514 ZNF610 ZNF713 ZNF732 ZNF718 ZNF257 ZNF764 ZNF253 ZNF92 ZNF611 ZNF816 ZNF737 ZNF506 ZNF534 ZNF727 ZNF479 ZNF808 ZNF578 ZNF766 ZNF701 ZNF860 ZNF85 ZNF30 ZFP69B ZNF90 ZNF91 ZNF98 ZNF583 ZNF445 | 2.36e-40 | 808 | 104 | 50 | SM00355 |
| Domain | zf-C2H2_6 | ZNF729 ZNF141 ZNF527 ZNF573 ZNF486 ZNF695 ZNF354A ZNF273 ZNF195 ZFP28 ZNF736 ZNF354B ZNF251 ZNF677 ZNF514 ZNF732 ZNF718 ZNF253 ZNF92 ZNF611 ZNF816 ZNF737 ZNF506 ZNF727 ZNF479 ZNF808 ZNF578 ZNF766 ZNF701 ZNF860 ZNF85 ZNF30 ZFP69B ZNF90 ZNF91 ZNF98 ZNF445 | 1.96e-39 | 314 | 104 | 37 | PF13912 |
| Domain | Znf_C2H2-like | ZNF729 ZNF141 ZNF527 ZNF573 ZNF486 ZNF695 ZNF354A ZNF273 ZNF559 ZNF254 ZNF485 ZIM2 ZNF195 ZFP28 ZNF736 ZNF519 ZNF354B ZNF251 ZNF3 ZNF677 ZNF514 ZNF610 ZNF713 ZNF732 ZNF718 ZNF257 ZNF764 ZNF253 ZNF92 ZNF611 ZNF816 ZNF737 ZNF506 ZNF534 ZNF727 ZNF479 ZNF808 ZNF578 ZNF766 ZNF701 ZNF860 ZNF85 ZNF30 ZFP69B ZNF90 ZNF91 ZNF98 ZNF583 ZNF445 | 2.45e-39 | 796 | 104 | 49 | IPR015880 |
| Domain | NatA_aux_su | NAA15 NAA16 | 3.07e-05 | 2 | 104 | 2 | IPR021183 |
| Domain | Clathrin_H-chain_propeller_rpt | CLTCL1 CLTC | 3.07e-05 | 2 | 104 | 2 | IPR022365 |
| Domain | NARP1 | NAA15 NAA16 | 3.07e-05 | 2 | 104 | 2 | PF12569 |
| Domain | Clathrin-link | CLTCL1 CLTC | 3.07e-05 | 2 | 104 | 2 | PF09268 |
| Domain | - | CLTCL1 CLTC | 3.07e-05 | 2 | 104 | 2 | 2.130.10.110 |
| Domain | Clathrin_H-chain_link/propller | CLTCL1 CLTC | 3.07e-05 | 2 | 104 | 2 | IPR016025 |
| Domain | Clathrin_propel | CLTCL1 CLTC | 3.07e-05 | 2 | 104 | 2 | PF01394 |
| Domain | Clathrin_heavy_chain | CLTCL1 CLTC | 3.07e-05 | 2 | 104 | 2 | IPR016341 |
| Domain | Clathrin_H-chain_linker_core | CLTCL1 CLTC | 3.07e-05 | 2 | 104 | 2 | IPR015348 |
| Domain | Clathrin_H-chain_propeller_N | CLTCL1 CLTC | 3.07e-05 | 2 | 104 | 2 | IPR001473 |
| Domain | Clathrin_H-chain_linker | CLTCL1 CLTC | 9.18e-05 | 3 | 104 | 2 | IPR012331 |
| Domain | CLH | CLTCL1 CLTC | 9.18e-05 | 3 | 104 | 2 | SM00299 |
| Domain | Clathrin | CLTCL1 CLTC | 6.33e-04 | 7 | 104 | 2 | PF00637 |
| Domain | CHCR | CLTCL1 CLTC | 6.33e-04 | 7 | 104 | 2 | PS50236 |
| Domain | Clathrin_H-chain/VPS_repeat | CLTCL1 CLTC | 8.41e-04 | 8 | 104 | 2 | IPR000547 |
| Domain | - | UTP6 NAA15 CLTCL1 EIF3L CLTC NAA16 | 1.06e-03 | 207 | 104 | 6 | 1.25.40.10 |
| Domain | zf-C2H2_11 | ZNF354A ZNF354B | 1.08e-03 | 9 | 104 | 2 | PF16622 |
| Domain | TPR-like_helical_dom | UTP6 NAA15 CLTCL1 EIF3L CLTC NAA16 | 1.94e-03 | 233 | 104 | 6 | IPR011990 |
| Domain | Myosin-like_IQ_dom | IQGAP1 ASPM | 4.94e-03 | 19 | 104 | 2 | IPR027401 |
| Domain | - | IQGAP1 ASPM | 4.94e-03 | 19 | 104 | 2 | 4.10.270.10 |
| Domain | EF-hand-dom_pair | CIB3 TBC1D8B MICU3 MRPS26 UTRN SLC25A23 | 5.40e-03 | 287 | 104 | 6 | IPR011992 |
| Domain | CH | IQGAP1 ASPM UTRN | 5.70e-03 | 65 | 104 | 3 | SM00033 |
| Domain | CH | IQGAP1 ASPM UTRN | 7.01e-03 | 70 | 104 | 3 | PF00307 |
| Domain | IQ | MYO1C IQGAP1 ASPM | 7.29e-03 | 71 | 104 | 3 | PF00612 |
| Domain | - | IQGAP1 ASPM UTRN | 7.29e-03 | 71 | 104 | 3 | 1.10.418.10 |
| Domain | CH | IQGAP1 ASPM UTRN | 7.87e-03 | 73 | 104 | 3 | PS50021 |
| Domain | 4_helix_cytokine-like_core | ZNF254 ZNF506 ZNF85 | 8.17e-03 | 74 | 104 | 3 | IPR009079 |
| Domain | CH-domain | IQGAP1 ASPM UTRN | 8.47e-03 | 75 | 104 | 3 | IPR001715 |
| Pathway | REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION | ZNF729 ZNF141 ZNF573 ZNF486 ZNF354A ZNF273 ZNF559 ZNF254 ZNF485 ZIM2 ZNF195 ZFP28 ZNF736 ZNF519 YES1 ZNF354B ZNF595 ZNF3 ZNF677 ZNF514 ZNF610 ZNF713 ZNF732 ZNF718 ZNF257 ZNF764 ZNF253 ZNF92 ZNF611 ZNF737 ZNF506 ZNF727 ZNF479 ZNF701 ZNF860 ZNF30 ZFP69B ZNF583 ZNF445 | 5.35e-18 | 1387 | 84 | 39 | M734 |
| Pathway | REACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS_BY_KRAB_ZFP_PROTEINS | ZNF141 ZNF354A ZNF273 ZNF519 ZNF610 ZNF257 ZNF816 ZNF534 ZNF30 | 1.36e-08 | 107 | 84 | 9 | M48260 |
| Pathway | REACTOME_GENERIC_TRANSCRIPTION_PATHWAY | ZNF729 ZNF695 ZNF354A ZNF254 ZNF195 ZFP28 ZNF736 ZNF519 ZNF354B ZNF595 ZNF3 ZNF610 ZNF764 ZNF727 ZNF808 ZNF85 ZNF91 ZNF583 ZNF445 | 9.02e-08 | 768 | 84 | 19 | MM14851 |
| Pathway | REACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS | ZNF141 ZNF354A ZNF273 ZNF519 ZNF610 ZNF257 ZNF816 ZNF534 ZNF30 | 1.61e-07 | 142 | 84 | 9 | M48257 |
| Pathway | REACTOME_GENE_EXPRESSION_TRANSCRIPTION | ZNF729 ZNF695 ZNF354A MYO1C ZNF254 ZNF195 ZFP28 ZNF736 ZNF519 ZNF354B ZNF595 ZNF3 ZNF610 ZNF764 ZNF727 ZNF808 ZNF85 ZNF91 ZNF583 ZNF445 | 1.65e-06 | 1022 | 84 | 20 | MM15436 |
| Pathway | REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION | ZNF141 ZNF354A MYO1C ZNF273 ZNF519 ZNF610 ZNF257 ZNF816 ZNF534 ZNF30 | 2.59e-06 | 254 | 84 | 10 | M27131 |
| Pathway | REACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS | ZNF354A ZNF254 ZNF595 ZNF610 | 3.40e-04 | 56 | 84 | 4 | MM17236 |
| Pubmed | Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells. | ZNF486 ZNF354A ZNF273 ZNF485 ZNF195 ZNF736 ZNF354B ZNF595 ZNF718 ZNF257 ZNF764 ZNF253 ZNF92 ZNF611 ZNF737 ZNF766 ZNF701 ZNF90 ZNF91 ZNF98 ZNF583 ZNF445 | 3.26e-29 | 181 | 106 | 22 | 37372979 |
| Pubmed | Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression. | ZNF729 ZNF695 ZNF254 ZNF195 ZNF736 ZNF595 ZNF718 ZNF506 ZNF727 ZNF85 ZNF91 | 4.08e-21 | 29 | 106 | 11 | 14563677 |
| Pubmed | Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR. | ZNF729 ZNF695 ZNF736 ZNF610 ZNF727 ZNF85 ZNF91 ZNF445 | 2.31e-12 | 49 | 106 | 8 | 9630514 |
| Pubmed | Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells. | ZNF92 ZNF737 ZNF85 ZNF90 ZNF91 ZNF98 | 5.42e-12 | 16 | 106 | 6 | 8467795 |
| Pubmed | The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins. | ZNF92 ZNF85 ZNF90 ZNF91 | 5.65e-09 | 8 | 106 | 4 | 2023909 |
| Pubmed | Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2. | ZNF729 ZNF254 ZNF595 ZNF91 | 1.08e-07 | 15 | 106 | 4 | 15885501 |
| Pubmed | Cys2His2 zinc finger protein family: classification, functions, and major members. | ZNF595 ZNF732 ZNF727 | 5.47e-07 | 6 | 106 | 3 | 22803940 |
| Pubmed | Molecular cloning of six novel Krüppel-like zinc finger genes from hematopoietic cells and identification of a novel transregulatory domain KRNB. | ZNF254 ZNF257 ZNF253 | 5.47e-07 | 6 | 106 | 3 | 10585455 |
| Pubmed | ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold. | ZNF729 NAA15 ZNF251 ZNF718 ZNF257 EIF3L ZNF506 ZNF766 ZNF701 ZNF91 | 1.28e-06 | 451 | 106 | 10 | 36168627 |
| Pubmed | Comparative analysis of KRAB zinc finger proteins in rodents and man: evidence for several evolutionarily distinct subfamilies of KRAB zinc finger genes. | ZNF254 ZNF195 ZNF595 | 2.28e-06 | 9 | 106 | 3 | 10360839 |
| Pubmed | Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. | CLTCL1 ZNF695 MYO1C ZNF254 SEMA3G ECE1 HEPH ADD2 ZNF718 VPS13A ZNF808 ZFP69B ZNF90 LZTS2 UTRN | 4.28e-06 | 1215 | 106 | 15 | 15146197 |
| Pubmed | Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. | ZNF729 ZNF254 ZNF195 ZFP28 ZNF595 ZNF3 ZNF610 ZNF718 ZNF764 ZNF506 ZNF91 ZNF445 | 6.82e-06 | 808 | 106 | 12 | 20412781 |
| Pubmed | The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step. | CLTCL1 CLTC | 9.20e-06 | 2 | 106 | 2 | 20065094 |
| Pubmed | Characterization of a second human clathrin heavy chain polypeptide gene (CLH-22) from chromosome 22q11. | CLTCL1 CLTC | 9.20e-06 | 2 | 106 | 2 | 8733129 |
| Pubmed | CHC22 and CHC17 clathrins have distinct biochemical properties and display differential regulation and function. | CLTCL1 CLTC | 9.20e-06 | 2 | 106 | 2 | 29097553 |
| Pubmed | Characterization of the mouse Kid1 gene and identification of a highly related gene, Kid2. | ZNF354A ZNF354B | 9.20e-06 | 2 | 106 | 2 | 10564808 |
| Pubmed | Functional equivalence of the clathrin heavy chains CHC17 and CHC22 in endocytosis and mitosis. | CLTCL1 CLTC | 2.76e-05 | 3 | 106 | 2 | 19509056 |
| Pubmed | Iron promotes oxidative cell death caused by bisretinoids of retina. | ABCA4 HEPH | 2.76e-05 | 3 | 106 | 2 | 29686088 |
| Pubmed | Clathrin isoform CHC22, a component of neuromuscular and myotendinous junctions, binds sorting nexin 5 and has increased expression during myogenesis and muscle regeneration. | CLTCL1 CLTC | 2.76e-05 | 3 | 106 | 2 | 15133132 |
| Pubmed | Clathrin promotes centrosome integrity in early mitosis through stabilization of centrosomal ch-TOG. | CLTCL1 CLTC | 2.76e-05 | 3 | 106 | 2 | 22891263 |
| Pubmed | Chorein, the protein responsible for chorea-acanthocytosis, interacts with β-adducin and β-actin. | ADD2 VPS13A | 2.76e-05 | 3 | 106 | 2 | 24129186 |
| Pubmed | Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia. | ZNF254 ZNF195 ZNF595 | 3.02e-05 | 20 | 106 | 3 | 2542606 |
| Pubmed | Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea. | ZNF254 ZNF195 ZNF595 | 3.02e-05 | 20 | 106 | 3 | 7479878 |
| Pubmed | Evolution of KRAB-containing zinc finger proteins and their roles in species evolution. | ZNF732 ZNF727 | 5.50e-05 | 4 | 106 | 2 | 27867147 |
| Pubmed | Zinc fingers function cooperatively with KRAB domain for nuclear localization of KRAB-containing zinc finger proteins. | ZNF732 ZNF727 | 5.50e-05 | 4 | 106 | 2 | 24647005 |
| Pubmed | HIP1 functions in clathrin-mediated endocytosis through binding to clathrin and adaptor protein 2. | CLTCL1 CLTC | 5.50e-05 | 4 | 106 | 2 | 11517213 |
| Pubmed | A novel human NatA Nalpha-terminal acetyltransferase complex: hNaa16p-hNaa10p (hNat2-hArd1). | NAA15 NAA16 | 9.15e-05 | 5 | 106 | 2 | 19480662 |
| Pubmed | An evolutionarily conserved N-terminal acetyltransferase complex associated with neuronal development. | NAA15 NAA16 | 9.15e-05 | 5 | 106 | 2 | 12888564 |
| Pubmed | Clathrin assembly lymphoid myeloid leukemia (CALM) protein: localization in endocytic-coated pits, interactions with clathrin, and the impact of overexpression on clathrin-mediated traffic. | CLTCL1 CLTC | 9.15e-05 | 5 | 106 | 2 | 10436022 |
| Pubmed | Characterization of hARD2, a processed hARD1 gene duplicate, encoding a human protein N-alpha-acetyltransferase. | NAA15 NAA16 | 9.15e-05 | 5 | 106 | 2 | 16638120 |
| Pubmed | A pair of mouse KRAB zinc finger proteins modulates multiple indicators of female reproduction. | ZNF254 ZNF595 | 9.15e-05 | 5 | 106 | 2 | 20042539 |
| Pubmed | The KRAB zinc finger protein RSL1 modulates sex-biased gene expression in liver and adipose tissue to maintain metabolic homeostasis. | ZNF254 ZNF595 | 9.15e-05 | 5 | 106 | 2 | 24190968 |
| Pubmed | The human genome contains hundreds of genes coding for finger proteins of the Krüppel type. | ZNF85 ZNF91 | 1.37e-04 | 6 | 106 | 2 | 2505992 |
| Pubmed | The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons. | ZNF254 ZNF595 | 1.37e-04 | 6 | 106 | 2 | 30846446 |
| Pubmed | The KRAB zinc finger protein RSL1 regulates sex- and tissue-specific promoter methylation and dynamic hormone-responsive chromatin configuration. | ZNF254 ZNF595 | 1.91e-04 | 7 | 106 | 2 | 22801370 |
| Pubmed | A role for the CHC22 clathrin heavy-chain isoform in human glucose metabolism. | CLTCL1 CLTC | 1.91e-04 | 7 | 106 | 2 | 19478182 |
| Pubmed | SLFN11 Inactivation Induces Proteotoxic Stress and Sensitizes Cancer Cells to Ubiquitin Activating Enzyme Inhibitor TAK-243. | MYO1C YES1 EIF3L ZNF91 | 2.10e-04 | 95 | 106 | 4 | 33863777 |
| Pubmed | Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach. | CD109 ECE1 CTSA | 2.15e-04 | 38 | 106 | 3 | 16263699 |
| Pubmed | p120 Catenin-associated Fer and Fyn tyrosine kinases regulate beta-catenin Tyr-142 phosphorylation and beta-catenin-alpha-catenin Interaction. | YES1 FER | 2.55e-04 | 8 | 106 | 2 | 12640114 |
| Pubmed | TAPP2 links phosphoinositide 3-kinase signaling to B-cell adhesion through interaction with the cytoskeletal protein utrophin: expression of a novel cell adhesion-promoting complex in B-cell leukemia. | CLTCL1 CLTC UTRN | 2.70e-04 | 41 | 106 | 3 | 19786618 |
| Pubmed | Novel activity of KRAB domain that functions to reinforce nuclear localization of KRAB-containing zinc finger proteins by interacting with KAP1. | ZNF354A ZNF91 | 3.27e-04 | 9 | 106 | 2 | 23665872 |
| Pubmed | Functional analysis of the SRY-KRAB interaction in mouse sex determination. | ZNF729 ZNF91 | 4.08e-04 | 10 | 106 | 2 | 18588511 |
| Pubmed | CALM regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature. | CLTCL1 CLTC | 4.08e-04 | 10 | 106 | 2 | 25898166 |
| Pubmed | A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis. | MYO1C YES1 CLTC UTRN | 4.79e-04 | 118 | 106 | 4 | 27377895 |
| Pubmed | Src, Fyn, and Yes are not required for neuromuscular synapse formation but are necessary for stabilization of agrin-induced clusters of acetylcholine receptors. | YES1 UTRN | 4.97e-04 | 11 | 106 | 2 | 11312300 |
| Pubmed | Sry associates with the heterochromatin protein 1 complex by interacting with a KRAB domain protein. | ZNF729 ZNF91 | 4.97e-04 | 11 | 106 | 2 | 15469996 |
| Pubmed | Ubiquitin-specific protease 8 deubiquitinates Sec31A and decreases large COPII carriers and collagen IV secretion. | CLTCL1 CLTC | 4.97e-04 | 11 | 106 | 2 | 29604273 |
| Pubmed | USP25-PKM2-glycolysis axis contributes to ischemia reperfusion-induced acute kidney injury by promoting M1-like macrophage polarization and proinflammatory response. | USP25 CLTC | 4.97e-04 | 11 | 106 | 2 | 36894047 |
| Pubmed | Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. | ZNF573 CLTCL1 MYO1C ZNF559 CD109 GCNT1 ECE1 HEPH ZNF3 ZNF92 ZNF85 ZNF583 | 5.84e-04 | 1293 | 106 | 12 | 15342556 |
| Pubmed | A synopsis of eukaryotic Nalpha-terminal acetyltransferases: nomenclature, subunits and substrates. | NAA15 NAA16 | 5.95e-04 | 12 | 106 | 2 | 19660095 |
| Pubmed | Overview of inactivating mutations in the protein-coding genome of the mouse reference strain C57BL/6J. | ZNF195 ZNF718 ZNF506 | 6.43e-04 | 55 | 106 | 3 | 29997285 |
| Pubmed | Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery. | ZNF729 ZNF91 | 7.02e-04 | 13 | 106 | 2 | 19850934 |
| Pubmed | Chromosomal location of fifteen unique mouse KRAB-containing zinc finger loci. | ZNF254 ZNF195 ZNF595 | 8.71e-04 | 61 | 106 | 3 | 8662221 |
| Pubmed | Large scale identification of human hepatocellular carcinoma-associated antigens by autoantibodies. | UTP6 KLHDC2 | 1.07e-03 | 16 | 106 | 2 | 12097419 |
| Pubmed | Genome-wide association analysis demonstrates the highly polygenic character of age-related hearing impairment. | GALNT17 FER | 1.36e-03 | 18 | 106 | 2 | 24939585 |
| Pubmed | KAP1 facilitates reinstatement of heterochromatin after DNA replication. | UTP6 DMAC2 ZNF195 YES1 IQGAP1 MRPS26 EIF3L CLTC | 1.43e-03 | 704 | 106 | 8 | 29955894 |
| Pubmed | Hrd1-mediated ACLY ubiquitination alleviate NAFLD in db/db mice. | MYO1C CLTC | 1.52e-03 | 19 | 106 | 2 | 32888949 |
| Pubmed | Promyelocytic leukemia protein interacts with the apoptosis-associated speck-like protein to limit inflammasome activation. | NAA15 MYO1C | 1.86e-03 | 21 | 106 | 2 | 24407287 |
| Pubmed | LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression. | ZNF354A MYO1C CD109 YES1 IQGAP1 EIF3L CLTC | 2.04e-03 | 580 | 106 | 7 | 35676659 |
| Pubmed | The X-Linked-Intellectual-Disability-Associated Ubiquitin Ligase Mid2 Interacts with Astrin and Regulates Astrin Levels to Promote Cell Division. | CEP128 ASPM | 2.04e-03 | 22 | 106 | 2 | 26748699 |
| Pubmed | LASP-1: a nuclear hub for the UHRF1-DNMT1-G9a-Snail1 complex. | MYO1C CLTC | 2.04e-03 | 22 | 106 | 2 | 25982273 |
| Pubmed | Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability. | MYO1C IQGAP1 CLTC UTRN | 2.83e-03 | 191 | 106 | 4 | 33762435 |
| Pubmed | Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy. | CLTCL1 CLTC | 2.85e-03 | 26 | 106 | 2 | 24067654 |
| Interaction | TRIM28 interactions | UTP6 ZNF527 ZNF573 ZNF486 ZNF695 ZNF354A ZNF273 DMAC2 ZNF254 ZNF485 ZIM2 ZNF195 ZNF736 YES1 ZNF354B ZNF595 IQGAP1 ZNF514 ZNF713 ZNF732 ZNF718 ZNF257 ZNF764 ZNF253 ZNF92 MRPS26 EIF3L CLTC ZNF611 ZNF816 ZNF737 ZNF808 ZNF766 ZNF701 ZNF85 ZNF30 ZNF90 ZNF91 ZNF98 ZNF583 ZNF445 | 2.65e-20 | 1474 | 104 | 41 | int:TRIM28 |
| Interaction | FBLN5 interactions | KLHDC2 ZNF273 ZNF195 ZNF764 ZNF253 ZNF92 ZNF737 UTRN | 1.71e-06 | 159 | 104 | 8 | int:FBLN5 |
| Interaction | LTBP2 interactions | ZNF273 ZNF254 ZNF251 ZNF92 ZNF611 ZNF766 | 5.13e-06 | 85 | 104 | 6 | int:LTBP2 |
| Interaction | ZNF195 interactions | ZNF695 ZNF195 ZNF677 ZNF718 ZNF764 | 1.12e-05 | 57 | 104 | 5 | int:ZNF195 |
| Cytoband | Ensembl 112 genes in cytogenetic band chr19p12 | ZNF729 ZNF486 ZNF254 ZNF257 ZNF66 ZNF737 ZNF85 ZNF723 ZNF90 ZNF91 ZNF98 | 6.61e-15 | 122 | 106 | 11 | chr19p12 |
| Cytoband | 19p12 | ZNF729 ZNF486 ZNF254 ZNF66 ZNF737 ZNF85 ZNF723 ZNF90 ZNF91 ZNF98 | 1.37e-14 | 90 | 106 | 10 | 19p12 |
| Cytoband | 19q13.41 | ZNF610 ZNF611 ZNF816 ZNF534 ZNF808 ZNF578 ZNF766 ZNF701 | 1.27e-11 | 78 | 106 | 8 | 19q13.41 |
| Cytoband | Ensembl 112 genes in cytogenetic band chr19q13 | ZNF527 ZNF573 DMAC2 ZIM2 ZFP28 ZNF677 ZNF610 DYRK1B ZNF611 ZNF816 ZNF534 ZNF808 ZNF578 ZNF766 ZNF701 ZNF30 ZNF583 | 2.20e-09 | 1192 | 106 | 17 | chr19q13 |
| Cytoband | 7q11.21 | ZNF273 ZNF736 ZNF92 ZNF727 | 4.29e-05 | 83 | 106 | 4 | 7q11.21 |
| Cytoband | 4p16.3 | ZNF141 ZNF595 ZNF732 ZNF718 | 4.71e-05 | 85 | 106 | 4 | 4p16.3 |
| Cytoband | Ensembl 112 genes in cytogenetic band chr7q11 | ZNF273 ZNF736 GALNT17 ZNF92 ZNF727 | 4.31e-04 | 271 | 106 | 5 | chr7q11 |
| Cytoband | 1p22 | ABCA4 OLFM3 | 9.76e-04 | 20 | 106 | 2 | 1p22 |
| Cytoband | Ensembl 112 genes in cytogenetic band chr4p16 | ZNF141 ZNF595 ZNF732 ZNF718 | 1.80e-03 | 222 | 106 | 4 | chr4p16 |
| GeneFamily | Zinc fingers C2H2-type|ZF class homeoboxes and pseudogenes | ZNF729 ZNF141 ZNF527 ZNF573 ZNF486 ZNF695 ZNF354A ZNF273 ZNF559 ZNF254 ZNF485 ZIM2 ZNF195 ZFP28 ZNF736 ZNF519 ZNF354B ZNF251 ZNF595 ZNF3 ZNF677 ZNF514 ZNF610 ZNF713 ZNF732 ZNF718 ZNF257 ZNF764 ZNF253 ZNF92 ZNF611 ZNF816 ZNF737 ZNF506 ZNF534 ZNF727 ZNF479 ZNF808 ZNF578 ZNF766 ZNF701 ZNF860 ZNF85 ZNF30 ZFP69B ZNF90 ZNF91 ZNF98 ZNF583 ZNF445 | 1.73e-48 | 718 | 84 | 50 | 28 |
| GeneFamily | N(alpha)-acetyltransferase subunits|GCN5 related N-acetyltransferases | NAA15 NAA16 | 1.37e-03 | 12 | 84 | 2 | 660 |
| Coexpression | GAUTAM_EYE_CORNEA_CYTOTOXIC_T_CELLS | SPTLC3 ZNF573 DMAC2 PCTP FAM13A ZNF92 ASPM | 2.28e-06 | 148 | 105 | 7 | M43625 |
| Coexpression | COATES_MACROPHAGE_M1_VS_M2_UP | ZNF729 ZNF695 ZNF736 ZNF727 ZNF85 ZNF91 | 3.53e-06 | 102 | 105 | 6 | MM749 |
| Coexpression | MIKKELSEN_NPC_ICP_WITH_H3K4ME3 | ZNF729 ZNF695 ZNF254 ZNF195 ZNF736 ZNF354B ZNF595 FAM13A ZNF727 ZNF85 ZNF91 | 5.11e-06 | 497 | 105 | 11 | MM863 |
| Coexpression | HAMAI_APOPTOSIS_VIA_TRAIL_UP | ZNF486 NAA15 USP25 ZNF195 ZNF354B DNAJB14 SNX13 ZNF257 ASPM ZNF611 FER ZNF85 | 1.28e-05 | 656 | 105 | 12 | M18979 |
| Coexpression | GSE40666_UNTREATED_VS_IFNA_STIM_STAT4_KO_EFFECTOR_CD8_TCELL_90MIN_DN | ABCA4 ZFP28 GCNT1 DENND11 TBC1D8B ZNF514 UTRN | 1.59e-05 | 199 | 105 | 7 | M9236 |
| ToppCell | 356C-Lymphocytic-NK_cells-NK_cell_E|356C / Donor, Lineage, Cell class and subclass (all cells) | ZNF527 ZNF573 ZNF273 ZNF485 ZNF3 ZNF583 | 2.70e-06 | 164 | 106 | 6 | d5bb57c321f2973836efc8990449494cc1fb87c7 |
| ToppCell | TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Papillary_Adenocarcinoma-4|TCGA-Lung / Sample_Type by Project: Shred V9 | ZNF729 ZNF534 ZNF479 ZNF578 ZNF98 | 6.94e-06 | 111 | 106 | 5 | bcecf3498a5fbd52dcdf56e68858b2da39d96ba9 |
| ToppCell | (1)_T_cells-(1)_T_CD4_naive|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1) | ATG9B ZNF141 ZNF573 ADD2 FAM13A NAA16 | 7.30e-06 | 195 | 106 | 6 | d3fa551bc6f5ee5890af1040415e61ecd5d46201 |
| Drug | AC1L1IPS | CLTCL1 CTSA CLTC | 1.83e-06 | 6 | 104 | 3 | CID000004682 |
| Drug | Antagonist G | CLTCL1 CTSA CLTC | 7.62e-06 | 9 | 104 | 3 | CID000163960 |
| Disease | longevity | UTP6 ECE1 STEAP2 FAM13A MRPS14 ZFP69B | 4.00e-04 | 284 | 99 | 6 | EFO_0004300 |
| Disease | response to radiation, hearing loss, response to antineoplastic agent | BBS2 ZNF66 ZNF85 | 5.01e-04 | 46 | 99 | 3 | EFO_0004238, GO_0009314, GO_0097327 |
| Disease | intellectual disability (implicated_via_orthology) | NAA15 DYRK1B NAA16 | 2.08e-03 | 75 | 99 | 3 | DOID:1059 (implicated_via_orthology) |
| Disease | pulmonary embolism | ZNF808 ZNF701 | 3.18e-03 | 25 | 99 | 2 | EFO_0003827 |
| Disease | colorectal cancer, breast carcinoma | ZNF808 ZNF578 | 3.44e-03 | 26 | 99 | 2 | EFO_0000305, MONDO_0005575 |
| Disease | D dimer measurement | ABCA4 GCNT1 | 4.56e-03 | 30 | 99 | 2 | EFO_0004507 |
| Disease | fibrinogen measurement | ZNF251 SNX13 OLFM3 | 5.95e-03 | 109 | 99 | 3 | EFO_0004623 |
