Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionallyl-alcohol dehydrogenase activity

AKR1B10 AKR1B15 AKR1A1

2.03e-074753GO:0047655
GeneOntologyMolecularFunctionaldose reductase (NADPH) activity

AKR1B10 AKR1B15 AKR1A1

1.80e-0514753GO:0004032
GeneOntologyMolecularFunctionicosanoid binding

CYP4F8 OXER1 CYP4F12

2.75e-0516753GO:0050542
GeneOntologyMolecularFunctionindanol dehydrogenase activity

AKR1B10 AKR1B15

8.31e-054752GO:0047718
GeneOntologyMolecularFunctionalpha-tocopherol omega-hydroxylase activity

CYP4F8 CYP4F12

1.38e-045752GO:0052871
GeneOntologyMolecularFunctionalcohol dehydrogenase (NADP+) activity

AKR1B10 AKR1B15 AKR1A1

1.40e-0427753GO:0008106
GeneOntologyMolecularFunctionlong-chain fatty acid binding

CYP4F8 OXER1 CYP4F12

1.56e-0428753GO:0036041
GeneOntologyMolecularFunctiongeranylgeranyl reductase activity

AKR1B10 AKR1B15

2.07e-046752GO:0045550
GeneOntologyMolecularFunctionaldo-keto reductase (NADPH) activity

AKR1B10 AKR1B15 AKR1A1

2.33e-0432753GO:0004033
GeneOntologyMolecularFunctionleukotriene-B4 20-monooxygenase activity

CYP4F8 CYP4F12

2.89e-047752GO:0050051
GeneOntologyMolecularFunctionalkane 1-monooxygenase activity

CYP4F8 CYP4F12

2.89e-047752GO:0018685
GeneOntologyMolecularFunctionNADP+ binding

AKR1B10 AKR1B15

4.93e-049752GO:0070401
GeneOntologyMolecularFunctionarachidonate omega-hydroxylase activity

CYP4F8 CYP4F12

6.14e-0410752GO:0052869
GeneOntologyMolecularFunctionfatty acid omega-hydroxylase activity

CYP4F8 CYP4F12

6.14e-0410752GO:0120250
GeneOntologyMolecularFunctionlong-chain fatty acid omega-hydroxylase activity

CYP4F8 CYP4F12

6.14e-0410752GO:0102033
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen

CYP4F8 CYP4F12

1.06e-0313752GO:0016713
GeneOntologyMolecularFunctionpeptide hormone binding

GIPR PIK3R1 HCRTR2

1.16e-0355753GO:0017046
GeneOntologyMolecularFunctionretinal dehydrogenase activity

AKR1B10 AKR1B15

1.23e-0314752GO:0001758
GeneOntologyMolecularFunctionarachidonate binding

CYP4F8 CYP4F12

1.42e-0315752GO:0050544
GeneOntologyMolecularFunctionall-trans-retinol dehydrogenase (NADP+) activity

AKR1B10 AKR1B15

1.42e-0315752GO:0052650
GeneOntologyMolecularFunctionicosatetraenoic acid binding

CYP4F8 CYP4F12

1.61e-0316752GO:0050543
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH2 DNAH9

2.05e-0318752GO:0008569
GeneOntologyMolecularFunctionfatty acid binding

CYP4F8 OXER1 CYP4F12

2.23e-0369753GO:0005504
GeneOntologyMolecularFunctionestradiol 17-beta-dehydrogenase [NAD(P)+] activity

AKR1B10 AKR1B15

2.53e-0320752GO:0004303
GeneOntologyMolecularFunctionphosphatidylcholine transporter activity

PITPNM2 ATP8B1

2.53e-0320752GO:0008525
GeneOntologyMolecularFunctionphospholipid transporter activity

PITPNM2 ATG9B ATP8B1

2.72e-0374753GO:0005548
GeneOntologyMolecularFunctionretinal binding

AKR1B10 AKR1B15

2.79e-0321752GO:0016918
GeneOntologyMolecularFunctionarachidonate epoxygenase activity

CYP4F8 CYP4F12

3.64e-0324752GO:0008392
GeneOntologyMolecularFunctionlipid binding

PITPNM2 CYP4F8 OXER1 PEBP1 AKR1B10 ATG2B AKR1B15 CYP4F12 ATP8B1 INPP4B

3.75e-039887510GO:0008289
GeneOntologyMolecularFunctionNADPH binding

AKR1B10 AKR1B15

4.27e-0326752GO:0070402
GeneOntologyMolecularFunctionarachidonate monooxygenase activity

CYP4F8 CYP4F12

4.60e-0327752GO:0008391
GeneOntologyMolecularFunctionphosphatidylinositol bisphosphate phosphatase activity

MTMR1 INPP4B

4.60e-0327752GO:0034593
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH2 DNAH9

4.94e-0328752GO:0051959
GeneOntologyMolecularFunctionphosphatidylinositol phosphate phosphatase activity

MTMR1 INPP4B

5.66e-0330752GO:0052866
GeneOntologyMolecularFunctionlipid transporter activity

PITPNM2 ATG9B ATG2B ATP8B1

6.36e-03196754GO:0005319
GeneOntologyMolecularFunctionsteroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

AKR1B10 AKR1B15

6.82e-0333752GO:0033764
GeneOntologyMolecularFunctionhormone binding

GIPR PIK3R1 HCRTR2

6.88e-03103753GO:0042562
GeneOntologyMolecularFunctionmonocarboxylic acid binding

CYP4F8 OXER1 CYP4F12

7.64e-03107753GO:0033293
GeneOntologyMolecularFunctionaromatase activity

CYP4F8 CYP4F12

7.64e-0335752GO:0070330
GeneOntologyBiologicalProcessorganic hydroxy compound metabolic process

CYP4F8 LMF1 ACLY ALG9 AKR1B10 AKR1B15 LSS SMPD1 CYP4F12 ATP8B1 AKR1A1 INPP4B

3.20e-066417512GO:1901615
GeneOntologyBiologicalProcessalcohol metabolic process

LMF1 ACLY ALG9 AKR1B10 AKR1B15 LSS SMPD1 AKR1A1 INPP4B

1.82e-05412759GO:0006066
GeneOntologyBiologicalProcesslipid biosynthetic process

PITPNM2 PIGT DHH ACLY PIK3R1 AKR1B15 PEX5 MTMR1 LSS SMPD1 HACD2 INPP4B

3.45e-058137512GO:0008610
GeneOntologyCellularComponentendoplasmic reticulum membrane

ATG9B CYP4F8 PIGT THADA LMF1 DHH RHBDF2 PIK3R1 VPS13C ALG9 ATG2B LSS CYP4F12 HACD2 CLSTN1 RNF139

7.71e-0612937316GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

ATG9B CYP4F8 PIGT THADA LMF1 DHH RHBDF2 PIK3R1 VPS13C ALG9 ATG2B LSS CYP4F12 HACD2 CLSTN1 RNF139

8.17e-0612997316GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

ATG9B CYP4F8 PIGT THADA LMF1 DHH RHBDF2 PIK3R1 VPS13C ALG9 ATG2B LSS CYP4F12 HACD2 CLSTN1 RNF139

1.07e-0513277316GO:0042175
GeneOntologyCellularComponentlipid droplet

VPS13C ATG2B LSS SMPD1

7.30e-04116734GO:0005811
DomainALDOKETO_REDUCTASE_1

AKR1B10 AKR1B15 AKR1A1

7.31e-0610753PS00798
DomainAldo/ket_reductase_CS

AKR1B10 AKR1B15 AKR1A1

7.31e-0610753IPR018170
DomainAldo/keto_reductase

AKR1B10 AKR1B15 AKR1A1

7.31e-0610753IPR020471
DomainALDOKETO_REDUCTASE_2

AKR1B10 AKR1B15 AKR1A1

7.31e-0610753PS00062
DomainALDOKETO_REDUCTASE_3

AKR1B10 AKR1B15 AKR1A1

7.31e-0610753PS00063
DomainATPase_dyneun-rel_AAA

VWA8 DNAH2 DNAH9

2.19e-0514753IPR011704
DomainAAA_5

VWA8 DNAH2 DNAH9

2.19e-0514753PF07728
Domain-

AKR1B10 AKR1B15 AKR1A1

3.35e-05167533.20.20.100
DomainNADP_OxRdtase_dom

AKR1B10 AKR1B15 AKR1A1

4.06e-0517753IPR023210
DomainAldo_ket_red

AKR1B10 AKR1B15 AKR1A1

4.06e-0517753PF00248
DomainAldo/ket_red/Kv-b

AKR1B10 AKR1B15 AKR1A1

4.06e-0517753IPR001395
Domain-

PEBP1 MRPL38

4.76e-0537523.90.280.10
DomainPBP

PEBP1 MRPL38

4.76e-053752PF01161
DomainPEBP

PEBP1 MRPL38

4.76e-053752IPR008914
DomainATG_C

VPS13C ATG2B

1.58e-045752PF09333
DomainAutophagy-rel_C

VPS13C ATG2B

1.58e-045752IPR015412
DomainVPS13_N

VPS13C ATG2B

4.39e-048752IPR026854
DomainChorein_N

VPS13C ATG2B

4.39e-048752PF12624
DomainDHC_N1

DNAH2 DNAH9

4.39e-048752PF08385
DomainDynein_heavy_dom-1

DNAH2 DNAH9

4.39e-048752IPR013594
DomainTPR_REGION

TTC21B DNAH2 PEX5 PRMT9 ZFC3H1

5.31e-04165755PS50293
DomainTPR

TTC21B DNAH2 PEX5 PRMT9 ZFC3H1

5.31e-04165755PS50005
DomainDynein_heavy_chain_D4_dom

DNAH2 DNAH9

1.40e-0314752IPR024317
DomainDynein_HC_stalk

DNAH2 DNAH9

1.40e-0314752IPR024743
DomainDynein_heavy_dom-2

DNAH2 DNAH9

1.40e-0314752IPR013602
DomainDHC_N2

DNAH2 DNAH9

1.40e-0314752PF08393
DomainMT

DNAH2 DNAH9

1.40e-0314752PF12777
DomainAAA_8

DNAH2 DNAH9

1.40e-0314752PF12780
DomainDHC_fam

DNAH2 DNAH9

1.62e-0315752IPR026983
DomainDynein_heavy_dom

DNAH2 DNAH9

1.62e-0315752IPR004273
DomainDynein_heavy

DNAH2 DNAH9

1.62e-0315752PF03028
DomainMAM_1

MAMDC2 PTPRT

1.84e-0316752PS00740
DomainMAM

MAMDC2 PTPRT

2.08e-0317752SM00137
DomainMAM

MAMDC2 PTPRT

2.34e-0318752PF00629
DomainMAM_dom

MAMDC2 PTPRT

2.34e-0318752IPR000998
DomainMAM_2

MAMDC2 PTPRT

2.34e-0318752PS50060
DomainTPR-contain_dom

TTC21B PEX5 PRMT9 ZFC3H1

3.12e-03150754IPR013026
PathwayREACTOME_CALNEXIN_CALRETICULIN_CYCLE

EDEM3 GANAB UGGT2 RNF139

3.36e-0626574M907
PathwayREACTOME_METABOLISM_OF_LIPIDS

PITPNM2 CYP4F8 ACLY PIK3R1 AKR1B10 AKR1B15 MTMR1 LSS SMPD1 CYP4F12 HACD2 INPP4B

5.41e-066205712MM15193
PathwayREACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE

EDEM3 GANAB UGGT2 RNF139

1.15e-0535574M918
PathwayREACTOME_ER_QUALITY_CONTROL_COMPARTMENT_ERQC

EDEM3 UGGT2 RNF139

7.92e-0521573M27875
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

ANKRD13A URB1 THADA GANAB ACLY DNAH2 UGGT2 LSS QRICH1 HACD2 CLSTN1 SYMPK

7.92e-07942751231073040
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

IGBP1 SLC4A7 GANAB ALG9 PAFAH1B2 NARS1 XPO4 LSS SMPD1 QRICH1 HACD2 RNF139 BIRC6 SOD2

8.23e-071327751432694731
Pubmed

Getting in and out from calnexin/calreticulin cycles.

EDEM3 GANAB UGGT2

2.71e-061375318303019
Pubmed

Role of AKR1B10 and AKR1B8 in the pathogenesis of non-alcoholic steatohepatitis (NASH) in mouse.

AKR1B10 AKR1B15

4.59e-06275234954342
Pubmed

Aldo-keto reductase family 1 member B8 is secreted via non-classical pathway.

AKR1B10 AKR1B15

4.59e-06275225120755
Pubmed

Murine aldo-keto reductase family 1 subfamily B: identification of AKR1B8 as an ortholog of human AKR1B10.

AKR1B10 AKR1B15

4.59e-06275221087085
Pubmed

Tissue-specific expression of two aldose reductase-like genes in mice: abundant expression of mouse vas deferens protein and fibroblast growth factor-regulated protein in the adrenal gland.

AKR1B10 AKR1B15

4.59e-0627528526877
Pubmed

AKR1B8 deficiency drives severe DSS-induced acute colitis through invasion of luminal bacteria and activation of innate immunity.

AKR1B10 AKR1B15

4.59e-06275236518763
Pubmed

Proline-rich tyrosine kinase 2 controls PI3-kinase activation downstream of the T cell antigen receptor in human T cells.

PTK2B PIK3R1

4.59e-06275225387834
Pubmed

Oxygenation of polyunsaturated long chain fatty acids by recombinant CYP4F8 and CYP4F12 and catalytic importance of Tyr-125 and Gly-328 of CYP4F8.

CYP4F8 CYP4F12

4.59e-06275216112640
Pubmed

1.7 A structure of FR-1, a fibroblast growth factor-induced member of the aldo-keto reductase family, complexed with coenzyme and inhibitor.

AKR1B10 AKR1B15

4.59e-0627527578036
Pubmed

Characterization of the promoter of the gene for a mouse vas deferens protein related to the aldo-keto reductase superfamily: effect of steroid hormones and phorbol esters.

AKR1B10 AKR1B15

4.59e-0627528541228
Pubmed

Impaired Barrier Function and Immunity in the Colon of Aldo-Keto Reductase 1B8 Deficient Mice.

AKR1B10 AKR1B15

4.59e-06275233644071
Pubmed

Protein profiling of the human epidermis from the elderly reveals up-regulation of a signature of interferon-gamma-induced polypeptides that includes manganese-superoxide dismutase and the p85beta subunit of phosphatidylinositol 3-kinase.

PIK3R1 SOD2

4.59e-06275212644569
Pubmed

Impaired self-renewal and increased colitis and dysplastic lesions in colonic mucosa of AKR1B8-deficient mice.

AKR1B10 AKR1B15

4.59e-06275225538260
Pubmed

Functional expression of novel human and murine AKR1B genes.

AKR1B10 AKR1B15

4.59e-06275221276782
Pubmed

Compensatory upregulation of aldo-keto reductase 1B10 to protect hepatocytes against oxidative stress during hepatocarcinogenesis.

AKR1B10 AKR1B15

4.59e-06275231911858
Pubmed

Thrombin-stimulated phosphatidylinositol 3-kinase activity in platelets is associated with activation of PYK2 tyrosine kinase: activation of both enzymes is aggregation independent.

PTK2B PIK3R1

4.59e-06275210797305
Pubmed

Genetic polymorphisms in nitric oxide synthase genes modify the relationship between vegetable and fruit intake and risk of non-Hodgkin lymphoma.

ATG9B AKR1A1 SOD2

7.68e-061875319423521
Pubmed

The inositol polyphosphate 4-phosphatase forms a complex with phosphatidylinositol 3-kinase in human platelet cytosol.

PIK3R1 INPP4B

1.37e-05375210097090
Pubmed

Pertussis toxin promotes macrophage survival through inhibition of acid sphingomyelinase and activation of the phosphoinositide 3-kinase/protein kinase B pathway.

PIK3R1 SMPD1

1.37e-05375217521884
Pubmed

Substrate specificity and catalytic efficiency of aldo-keto reductases with phospholipid aldehydes.

AKR1B10 AKR1B15

1.37e-05375217381426
Pubmed

Phosphatidylinositol-3-kinase activation mediates proline-rich tyrosine kinase 2 phosphorylation and recruitment to beta1-integrins in human CD34+ cells.

PTK2B PIK3R1

1.37e-05375215539082
Pubmed

A newly isolated Pex7-binding, atypical PTS2 protein P7BP2 is a novel dynein-type AAA+ protein.

VWA8 PEX5

1.37e-05375230204880
Pubmed

A delayed-early gene activated by fibroblast growth factor-1 encodes a protein related to aldose reductase.

AKR1B10 AKR1B15

1.37e-0537527510692
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

URB1 THADA SLC4A7 GANAB VWA8 PIK3R1 TUBGCP3 MTMR1 UGGT2 LSS MRPL38 ZFC3H1 THOC5

1.62e-051487751333957083
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

THADA SLC4A7 GANAB VWA8 PEBP1 PIK3R1 VPS13C SUPV3L1 ATG2B PEX5 MRPL38 BIRC6 YARS1

1.72e-051496751332877691
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

ANKRD13A PIGT THADA PIK3R1 PAFAH1B2 ATG2B TTC21B XPO4 UGGT2 MRPL38 HACD2 INVS

2.45e-051321751227173435
Pubmed

Aberrant methylation of ATG2B, ATG4D, ATG9A and ATG9B CpG island promoter is associated with decreased mRNA expression in sporadic breast carcinoma.

ATG9B ATG2B

2.75e-05475227265029
Pubmed

Disruption of mouse cytochrome p450 4f14 (Cyp4f14 gene) causes severe perturbations in vitamin E metabolism.

CYP4F8 CYP4F12

2.75e-05475222665481
Pubmed

Genetic variants in GCKR, GIPR, ADCY5 and VPS13C and the risk of severe sulfonylurea-induced hypoglycaemia in patients with type 2 diabetes.

GIPR VPS13C

2.75e-05475222956255
Pubmed

Effects of genetic variants in ADCY5, GIPR, GCKR and VPS13C on early impairment of glucose and insulin metabolism in children.

GIPR VPS13C

2.75e-05475221789219
Pubmed

Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14.

CYP4F8 CYP4F12

2.75e-05475211185557
Pubmed

Fibroblast growth factor 2-induced cytoplasmic asparaginyl-tRNA synthetase promotes survival of osteoblasts by regulating anti-apoptotic PI3K/Akt signaling.

PIK3R1 NARS1

2.75e-05475219631775
Pubmed

Identification of a novel family of targets of PYK2 related to Drosophila retinal degeneration B (rdgB) protein.

PITPNM2 PTK2B

2.75e-05475210022914
Pubmed

Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability.

ATG9B ATG2B

2.75e-05475219197948
Pubmed

Identification of genes and networks driving cardiovascular and metabolic phenotypes in a mouse F2 intercross.

AKR1B10 AKR1B15

2.75e-05475221179467
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

EDEM3 LMF1 SLC4A7 VPS13C ALG9 PEX5 UGGT2 BIRC6 STRIP2

2.84e-0573375934672954
Pubmed

Disruption of P450-mediated vitamin E hydroxylase activities alters vitamin E status in tocopherol supplemented mice and reveals extra-hepatic vitamin E metabolism.

CYP4F8 CYP4F12

4.57e-05575222969154
Pubmed

Comparisons of genomic structures and chromosomal locations of the mouse aldose reductase and aldose reductase-like genes.

AKR1B10 AKR1B15

4.57e-05575210092857
Pubmed

Cytochrome P4504f, a potential therapeutic target limiting neuroinflammation.

CYP4F8 CYP4F12

4.57e-05575221466787
Pubmed

Macrophage autophagy in immunity to Cryptococcus neoformans and Candida albicans.

ATG9B ATG2B

4.57e-05575222710871
Pubmed

Butylated hydroxyanisole induces distinct expression patterns of Nrf2 and detoxification enzymes in the liver and small intestine of C57BL/6 mice.

AKR1B10 AKR1B15

4.57e-05575226291391
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

EDEM3 PIGT THADA GANAB ACLY ALG9 UGGT2 SMPD1 HACD2 CLSTN1 SYMPK

5.15e-051201751135696571
Pubmed

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.

GIPR VPS13C

6.84e-05675220081857
Pubmed

The cytochrome P450 4 (CYP4) family.

CYP4F8 CYP4F12

6.84e-0567529068972
Pubmed

Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain.

MTMR1 THOC5 SYMPK

8.32e-053975322802532
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

CYP4F8 PIGT THADA RHBDF2 UGGT2 LSS ATP8B1 AKR1A1 HACD2 SYMPK

9.20e-051061751033845483
Pubmed

Mitochondrial alterations caused by defective peroxisomal biogenesis in a mouse model for Zellweger syndrome (PEX5 knockout mouse).

PEX5 SOD2

9.57e-05775211583975
Pubmed

Polycystic Kidney Disease, Autosomal Dominant

GANAB ALG9

9.57e-05775220301424
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH2 DNAH9

9.57e-05775231178125
Pubmed

Role of ω-hydroxylase in adenosine-mediated aortic response through MAP kinase using A2A-receptor knockout mice.

CYP4F8 CYP4F12

9.57e-05775222160543
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

THADA VPS13C ALG9 PEX5 MRPL38 HACD2 BIRC6 SOD2

1.60e-0471975835337019
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

URB1 ACLY VPS13C DNAH2 NARS1 BIRC6 PLS1 SYMPK

1.87e-0473675829676528
Pubmed

Polymorphisms in oxidative stress genes and risk for non-Hodgkin lymphoma.

AKR1A1 SOD2

2.04e-041075216543247
Pubmed

PEX19 is a predominantly cytosolic chaperone and import receptor for class 1 peroxisomal membrane proteins.

PXMP4 PEX5

2.04e-041075214709540
Pubmed

Genetic polymorphisms in the oxidative stress pathway and susceptibility to non-Hodgkin lymphoma.

AKR1A1 SOD2

2.04e-041075217149600
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

PIGT VWA8 ACLY TUBGCP3 LSS THOC5 SYMPK

2.08e-0456075735241646
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

EDEM3 URB1 PIGT WASHC4 VWA8 TUBGCP3 XPO4 UGGT2

2.21e-0475475833060197
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

PIGT LMF1 SLC4A7 GANAB VWA8 ACLY UGGT2 LSS HACD2 CLSTN1 SOD2

2.70e-041451751130550785
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

GANAB WASHC4 ACLY PAFAH1B2 NARS1 PEX5 OGFOD1 QRICH1 BIRC6 PLS1 YARS1

2.77e-041455751122863883
Pubmed

EDEM1 Drives Misfolded Protein Degradation via ERAD and Exploits ER-Phagy as Back-Up Mechanism When ERAD Is Impaired.

EDEM3 ATG2B UGGT2 RNF139

3.18e-0415075432423001
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PITPNM2 THADA LMF1 RHBDF2 VPS13C TTC21B LSS ATP8B1 CYB5D1 CAMTA1 INVS

3.37e-041489751128611215
Pubmed

Sox2-Evf2 lncRNA-mediated mechanisms of chromosome topological control in developing forebrain.

AKR1B10 AKR1B15

3.52e-041375233593819
Pubmed

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.

EDEM3 URB1 ACLY XPO4 UGGT2

3.86e-0428575532838362
Pubmed

Proteomic Analysis Reveals a Role for RSK in p120-catenin Phosphorylation and Melanoma Cell-Cell Adhesion.

SLC4A7 PIK3R1 PEX5 MTMR1

4.07e-0416075431678930
Pubmed

A bead-based approach for large-scale identification of in vitro kinase substrates.

MRPL38 ZFC3H1 BIRC6 THOC5

4.36e-0416375422113938
Pubmed

Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs.

URB1 PIGT HACD2 RNF139 BIRC6

4.58e-0429675534186245
Pubmed

Global landscape of HIV-human protein complexes.

ANKRD13A PTK2B EDEM3 GANAB XPO4 PLS1

4.67e-0445775622190034
Pubmed

Molecular cloning of murine STAP-1, the stem-cell-specific adaptor protein containing PH and SH2 domains.

PTK2B PIK3R1

4.73e-041575210679268
Pubmed

FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.

PIGT SLC4A7 GANAB ALG9 UGGT2 HACD2

5.29e-0446875631056421
Pubmed

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.

ANKRD13A THADA ACLY TUBGCP3 XPO4 BIRC6 YARS1

5.43e-0465775736180527
Pubmed

Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria.

CYP4F8 PIK3R1 CYP4F12

6.05e-047675322323595
Pubmed

Macrophage activation through CCR5- and CXCR4-mediated gp120-elicited signaling pathways.

PTK2B PIK3R1

6.11e-041775212960231
Pubmed

Signaling mechanism of HIV-1 gp120 and virion-induced IL-1beta release in primary human macrophages.

PTK2B PIK3R1

6.11e-041775218453587
Pubmed

Mutation analysis of 18 nephronophthisis associated ciliopathy disease genes using a DNA pooling and next generation sequencing strategy.

TTC21B INVS

6.87e-041875221068128
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

THADA TTC21B ZFC3H1 CLSTN1 BIRC6 THOC5

6.94e-0449375615368895
Pubmed

A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III.

PIGT VWA8 PIK3R1 XPO4 HACD2 BIRC6 PLS1

7.00e-0468675728380382
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

ANKRD13A THADA MTMR1 MRPL38 THOC5 YARS1 SYMPK

7.19e-0468975736543142
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

PIGT SLC4A7 WASHC4 PIK3R1 VPS13C ATG2B

7.78e-0450475634432599
Pubmed

Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.

PIGT VWA8 PIK3R1 SUPV3L1 QRICH1 BIRC6

8.70e-0451575631617661
Pubmed

Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family.

PIGT GANAB ACLY ATG2B NARS1 MTMR1 XPO4 MRPL38

8.87e-0493175827432908
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

GANAB PAFAH1B2 NARS1 BIRC6 YARS1

9.01e-0434475530333137
Pubmed

Nephronophthisis-Related Ciliopathies

TTC21B INVS

9.38e-042175227336129
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

PITPNM2 PTK2B SNPH PEBP1 ACLY AKR1B10 PAFAH1B2 NARS1 MTMR1 YARS1

9.81e-041431751037142655
Pubmed

Identification of Modifier Genes in a Mouse Model of Gaucher Disease.

MAMDC2 THOC5

1.03e-032275227568557
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

GANAB ACLY PAFAH1B2 DBR1 YARS1

1.10e-0336075533111431
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

PIGT SLC4A7 GANAB WASHC4 ALG9 LSS ZFC3H1 SOD2 SYMPK

1.11e-03120375929180619
Pubmed

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3.

GANAB PEBP1 ACLY PAFAH1B2 YARS1 SOD2

1.24e-0355275636293380
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

IGBP1 SLC4A7 VPS13C ALG9 ATG2B HACD2

1.44e-0356875637774976
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

IGBP1 THADA SLC4A7 PEBP1 VPS13C PEX5 BIRC6

1.44e-0377775735844135
Pubmed

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

URB1 VWA8 ZFC3H1

1.54e-031057539628581
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

GANAB PEBP1 ACLY VPS13C PAFAH1B2 NARS1 AKR1A1 PLS1

1.55e-03101675819056867
Pubmed

Role of the E3 ubiquitin-ligase Hakai in intestinal inflammation and cancer bowel disease.

ACLY NARS1

1.56e-032775236266428
Pubmed

Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development.

DHH AKR1B10

1.67e-032875221820362
Pubmed

Age-dependent effects of Armc5 haploinsufficiency on adrenocortical function.

GIPR AKR1B10

1.67e-032875228911199
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

CYP4F8 SLC4A7 GANAB PEBP1 ACLY PIK3R1 XPO4 YARS1 SOD2

1.75e-03128475917353931
Pubmed

An evaluation of the assembly of an approximately 15-Mb region on human chromosome 13q32-q33 linked to bipolar disorder and schizophrenia.

NALCN UGGT2

1.79e-032975211991713
Pubmed

A mitochondrial protein compendium elucidates complex I disease biology.

SNPH MPV17L2 ACLY SUPV3L1 AKR1B10 NARS1 MRPL38 SOD2

1.87e-03104775818614015
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

IGBP1 GANAB PIK3R1 MTMR1 XPO4 BIRC6 PTPRT SYMPK

1.89e-03104975827880917
InteractionDBNL interactions

CYP4F8 GANAB ACLY PLS1 INVS SSUH2 SYMPK

6.85e-06190757int:DBNL
InteractionAKR1B10 interactions

PIGT AKR1B10 AKR1B15 SSUH2

1.61e-0541754int:AKR1B10
Cytoband18q21.31

NARS1 ATP8B1

3.11e-041675218q21.31
Cytoband12q24.11

ANKRD13A WASHC4

1.35e-033375212q24.11
Cytoband11q23

ALG9 PAFAH1B2

1.60e-033675211q23
Cytoband7q33

AKR1B10 AKR1B15

2.07e-03417527q33
Cytoband19p13.1

CYP4F8 CYP4F12

2.83e-034875219p13.1
GeneFamilyAldo-keto reductases

AKR1B10 AKR1B15 AKR1A1

7.33e-0615473399
GeneFamilyDyneins, axonemal

DNAH2 DNAH9

8.77e-0417472536
GeneFamilyPhosphoinositide phosphatases

MTMR1 INPP4B

3.12e-03324721079
GeneFamilyAutophagy related

ATG9B ATG2B

3.32e-03334721022
GeneFamilyCytochrome P450 family 4

CYP4F8 CYP4F12

3.94e-03364721003
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

URB1 VPS13C XPO4 HACD2 BIRC6 INVS

8.54e-071917569454f642c3621370fa23640b631301346b300950
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLEKHG7 DNAH2 DNAH9 PTPRT SSUH2

9.83e-0616975514aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

GIPR PLEKHG7 DNAH2 DNAH9 PTPRT

1.52e-0518575530f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell15-Airway-Epithelial-Multiciliated_cell|Airway / Age, Tissue, Lineage and Cell class

GIPR ATG9B DNAH2 DNAH9 PTPRT

1.52e-051857550998b6bf44287eebbf39249fff23fc3689e44c4e
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GIPR PLEKHG7 DNAH2 DNAH9 PTPRT

1.60e-051877559e10ed56090d82589bc457788282f664b70ace4b
ToppCellRA-14._Fibroblast_III|World / Chamber and Cluster_Paper

SLC4A7 PRMT9 UGGT2 CYB5D1 SOD2

1.69e-05189755b6e12d24d2b0735730bdc625f8318c1c9c2a9b3b
Drugzopolrestat

AKR1B10 AKR1B15 AKR1A1 SOD2

1.80e-0627754CID000001613
DrugN(omega)-hydroxy-L-arginine

NALCN AKR1B10 AKR1A1 RNF139 SOD2

3.99e-0672755CID000123895
DrugDaunorubicin

PIK3R1 AKR1B10 SMPD1 AKR1A1 PLK3 INPP4B SOD2

7.21e-06216757ctd:D003630
DrugAL-4114

AKR1B10 AKR1A1 SOD2

7.39e-0612753CID000164424
Drugnaphthalene-1,2-dihydrodiol

CYP4F8 AKR1B10 CYP4F12 AKR1A1

1.46e-0545754CID000000362
Drugoregon green 488 carboxylate

AKR1B10 PEX5 AKR1A1 SOD2

1.60e-0546754CID005289081
Drugdaunorubicinol

AKR1B10 AKR1A1

3.21e-053752ctd:C000847
DrugEthosuximide [77-67-8]; Down 200; 28.4uM; PC3; HT_HG-U133A

SLC4A7 PIK3R1 TUBGCP3 MTMR1 DBR1 SOD2

4.77e-051977562116_DN
DrugMephentermine hemisulfate [1212-72-2]; Down 200; 9.4uM; PC3; HT_HG-U133A

THADA RHBDF2 TUBGCP3 PEX5 SOD2 INVS

4.90e-051987567384_DN
DrugOxantel pamoate [68813-55-8]; Down 200; 6.6uM; MCF7; HT_HG-U133A

VWA8 PIK3R1 PAFAH1B2 TUBGCP3 MTMR1 UGGT2

4.90e-051987565338_DN
DrugZomepirac sodium salt [64092-48-4]; Down 200; 12.8uM; HL60; HT_HG-U133A

LMF1 PIK3R1 PEX5 LSS SMPD1 PLS1

5.04e-051997562713_DN
Drugbenzene dihydrodiol

AKR1B10 AKR1A1 SYMPK

5.05e-0522753CID000000418
DrugAC1L1F9Q

CYP4F8 OXER1 PIK3R1 PEX5 CYP4F12 SOD2

5.33e-05201756CID000003144
Drugnaphthalene

CYP4F8 AKR1B10 CYP4F12 AKR1A1 PLS1

5.41e-05123755CID000000931
Drug5-Isothiocyanatoalrestatin

AKR1B10 AKR1A1

6.40e-054752CID000124861
DrugM7HEQ

AKR1B10 AKR1A1

6.40e-054752CID006452329
DrugNAP-HEX-Q

AKR1B10 AKR1A1

6.40e-054752CID005487149
DrugWF-2421

AKR1B10 AKR1A1

6.40e-054752CID000195567
Drugmatteuorienate A

AKR1B10 AKR1A1

6.40e-054752CID000190958
Drug5-azidoalrestatin

AKR1B10 AKR1A1

6.40e-054752CID000128442
Drug5-(3-Thienyl)tetrazol-1-yl)acetic acid

AKR1B10 AKR1A1

6.40e-054752CID003035658
DrugFR-62765

AKR1B10 AKR1A1

6.40e-054752CID000128354
Drugdanshenol B

AKR1B10 AKR1A1

6.40e-054752CID003083515
Drugiodomethanesulfonamide

AKR1B10 AKR1A1

6.40e-054752CID000519939
Drugsalviaflaside

AKR1B10 AKR1A1

6.40e-054752CID006438919
Drugkolaviron

AKR1B10 AKR1A1 SOD2

6.61e-0524753CID000155169
Drug9,10-phenanthrenequinone

AKR1B10 AKR1A1 SOD2

7.49e-0525753ctd:C005399
Drug2,3-hexanedione

AKR1B10 AKR1A1

1.06e-045752ctd:C043231
DrugAD-5467

AKR1B10 AKR1A1

1.06e-045752CID000197383
DrugM79175

AKR1B10 AKR1A1

1.06e-045752CID000115090
Drugxanthone-2

AKR1B10 AKR1A1

1.06e-045752CID005384285
DrugAC1L4VGL

AKR1B10 AKR1A1

1.06e-045752CID000213726
Drug4-chloro-3-nitrobenzaldehyde

AKR1B10 AKR1A1

1.06e-045752CID000085505
DrugICI 105552

AKR1B10 AKR1A1

1.06e-045752CID000133677
Drug2-(2,3,6-Trihydroxy-4-carboxyphenyl)ellagic acid

AKR1B10 AKR1A1

1.06e-045752CID006918808
DrugICI 222155

AKR1B10 AKR1A1

1.06e-045752CID000195716
DrugDN-108

AKR1B10 AKR1A1

1.06e-045752CID000183791
DrugBAL-ARI8

AKR1B10 AKR1A1

1.06e-045752CID000130098
Drugp225

AKR1B10 AKR1A1

1.59e-046752CID000014589
DrugICI 215918

AKR1B10 AKR1A1

1.59e-046752CID000129688
DrugAC1L28UN

AKR1B10 AKR1A1

1.59e-046752CID000068017
DrugM16287

AKR1B10 AKR1A1

1.59e-046752CID000188399
DrugADN-138

AKR1B10 AKR1A1

1.59e-046752CID000127323
DrugBAPSG

AKR1B10 AKR1A1

1.59e-046752CID000130998
Drugcapillarisin

AKR1B10 AKR1A1

1.59e-046752CID005281342
DiseaseSkin Abnormalities

SUPV3L1 LSS SOD2

4.43e-0613753C0037268
Diseaseurinary potassium to creatinine ratio

GIPR SLC4A7

9.50e-056752EFO_0009882
DiseaseNEPHRONOPHTHISIS 2

TTC21B INVS

1.77e-048752C1865872
Diseasesymmetrical dimethylarginine measurement

AKR1B10 AKR1B15

2.27e-049752EFO_0006523
DiseasePolycystic Kidney, Autosomal Dominant

GANAB ALG9

2.27e-049752C0085413
DiseasePapillary Renal Cell Carcinoma

PEBP1 RNF139 INPP4B SOD2

3.24e-04128754C1306837
DiseaseMalignant Neoplasms

PIK3R1 AKR1B10 BIRC6 SOD2

3.24e-04128754C0006826
DiseaseRenal Cell Carcinoma

PEBP1 RNF139 INPP4B SOD2

3.24e-04128754C0007134
DiseaseSarcomatoid Renal Cell Carcinoma

PEBP1 RNF139 INPP4B SOD2

3.24e-04128754C1266043
DiseaseChromophobe Renal Cell Carcinoma

PEBP1 RNF139 INPP4B SOD2

3.24e-04128754C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

PEBP1 RNF139 INPP4B SOD2

3.24e-04128754C1266044
DiseaseNephronophthisis

TTC21B INVS

4.88e-0413752C0687120
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

PEBP1 RNF139 INPP4B SOD2

5.60e-04148754C0279702
DiseaseBenign Neoplasm

AKR1B10 BIRC6 SOD2

7.02e-0468753C0086692
DiseaseNeoplasms

AKR1B10 BIRC6 SOD2

7.02e-0468753C0027651
DiseaseNecrotizing Enterocolitis

AKR1A1 SOD2

8.46e-0417752C0520459
Diseaseinterleukin 18 measurement

PIK3R1 BIRC6 PTPRT

9.70e-0476753EFO_0004581
Diseaseacetone measurement

GIPR VWA8

1.06e-0319752EFO_0010989
DiseasePancreatic carcinoma

INPP4B SOD2

1.06e-0319752C0235974
DiseaseAlopecia

SUPV3L1 LSS

1.06e-0319752C0002170
Diseaseheart failure

PXMP4 LMF1 AKR1A1 SYMPK

1.28e-03185754EFO_0003144
Diseasehyperglycemia (biomarker_via_orthology)

GIPR HCRTR2

1.30e-0321752DOID:4195 (biomarker_via_orthology)
DiseaseX-12063 measurement

EDEM3 TUBGCP3 XPO4 INPP4B

1.31e-03186754EFO_0021283
Diseaseglioma

LMF1 CYP4F12

1.42e-0322752EFO_0005543
DiseaseKidney Diseases

TTC21B SMPD1 SOD2

1.48e-0388753C0022658
DiseaseCharcot-Marie-Tooth disease (implicated_via_orthology)

MTMR1 YARS1

1.70e-0324752DOID:10595 (implicated_via_orthology)
Diseaseglucose tolerance test

GIPR VPS13C

2.15e-0327752EFO_0004307
DiseaseAmyotrophic Lateral Sclerosis With Dementia

DBR1 SOD2

2.48e-0329752C0393554

Protein segments in the cluster

PeptideGeneStartEntry
LYLWYTGEPNDALRH

TTC21B

1031

Q7Z4L5
YWLLQNPDIVLVHYL

CAMTA1

166

Q9Y6Y1
IPFWYHMYLDEEIRL

PRMT9

786

Q6P2P2
LWHSYELLVEYDLPA

BIRC6

3501

Q9NR09
AIPHWQLLYRARETY

SMPD1

531

P17405
IRSYAYLLLHAWPAA

ALG9

111

Q9H6U8
KLSYLDVYLIHWPQG

AKR1B10

101

O60218
YTWLLVEGVYLHSLL

GIPR

231

P48546
ASYEEVLHLLRYRNW

CLSTN1

766

O94985
LESIWEILHRYLPYN

CYB5D1

156

Q6P9G0
HLWSCALDYRPLYLP

ATG2B

1241

Q96BY7
YLQRLLLVHGRWSYI

ATP8B1

931

O43520
YPVASLSHLELWVNY

MTMR1

586

Q13613
DLYYVRFTEWLHEVL

QRICH1

571

Q2TAL8
SLPWILNEEGHYIYV

MAMDC2

41

Q7Z304
YPLHLLVWKNDYRQL

ANKRD13A

11

Q8IZ07
QDHEILYDWINPTYL

OGFOD1

261

Q8N543
LHYWYLSLDRLFPAS

MPV17L2

76

Q567V2
HPREDWYEQLYPLIL

INPP4B

571

O15327
DYIFTTEAHLLPLWL

EDEM3

486

Q9BZQ6
LSPEELLLRWVNYHL

PLS1

266

Q14651
EYYLLHLQRWIDISL

IGBP1

191

P78318
GLHRYVWLVYEQDRP

PEBP1

116

P30086
LRDWLRYTPAYAHLV

PEX5

426

P50542
YTPHSWLLRVVYALL

LSS

286

P48449
WLLRVVYALLNLYEH

LSS

291

P48449
LVSHPVLSFLYRWIY

TUBGCP3

421

Q96CW5
SIPHQYWLTLQYLLK

PIK3R1

231

P27986
VVRHWQDLGYLIIYV

PITPNM2

1136

Q9BZ72
PLRVDYYLLHETWRF

OXER1

146

Q8TDS5
IVQHLQYIGWPAYRD

PTPRT

1331

O14522
DEEFLRYLWREYLHP

HCRTR2

36

O43614
HWYSRLLYRLAEELL

DHH

381

O43323
LLNHLPYLIKWARYT

HACD2

156

Q6Y1H2
GLSWVLYNLARHPEY

CYP4F8

336

P98187
GLSWVLYNLARHPEY

CYP4F12

336

Q9HCS2
YWDIQVFYREALHIP

ATG9B

306

Q674R7
PDYLEYDIEWLTILR

DBR1

276

Q9UK59
WDLIRLYLHESNRVY

DNAH9

2701

Q9NYC9
LHVEAEWRYDLQIRY

PTK2B

121

Q14289
YWERLLFETPHYVVN

DNAH2

646

Q9P225
YEIWRELFSPLHALN

PAFAH1B2

56

P68402
YDNLFRTPLHWAALL

INVS

251

Q9Y283
ILPVLLSYVLWHHYA

RNF139

401

Q8WU17
PWELLELRVSYYENV

YARS1

86

P54577
RLLEYVYTHWEHPLD

THADA

391

Q6YHU6
KHQPDLIYLRYVPLW

SLC4A7

1066

Q9Y6M7
RLDLPEDFHYSYELW

STRIP2

801

Q9ULQ0
WILNRYHIRDVCLYP

NARS1

526

O43776
WYTLLYQAHREGIPV

GANAB

711

Q14697
VHDVLDLYLWLSYRF

SUPV3L1

631

Q8IYB8
EPKSYWSRHYIVDLL

SNPH

416

O15079
YEIIRDYSLLTWILH

URB1

1846

O60287
IELIPLTEVHYWYQG

SSUH2

331

Q9Y2M2
QGLYRHPWDDISYVL

ACLY

1081

P53396
KLSYLDVYLIHWPQG

AKR1B15

101

C9JRZ8
DLQLEYLDLYLMHWP

AKR1A1

101

P14550
WKARHTLLEPEVRYY

PLK3

151

Q9H4B4
YEDIHWLILVTGYLL

XPO4

536

Q9C0E2
LEPDAEYLHWLLTNI

MRPL38

226

Q96DV4
LDTVPWYLRLYVHTL

PIGT

386

Q969N2
EDWDVAYIIHLYPSL

VPS13C

2656

Q709C8
LIPLLGIDVWEHAYY

SOD2

176

P04179
IPRDHPYIQYNVLWE

SYMPK

216

Q92797
RRLYWDVTLENYSHL

ZNF41

91

P51814
LYWHRAVFPIYLDDV

WASHC4

606

Q2M389
YLQTHEYLLDVDLWR

PLEKHG7

321

Q6ZR37
YELLRGWRPYEIHSV

STK32B

216

Q9NY57
LNSHIWEYTYVLDIR

UGGT2

426

Q9NYU1
SDYVLELGHPYLWVQ

THOC5

431

Q13769
AIQWLYPYSILLGHE

VWA8

336

A3KMH1
PDQFYRLWLSLFLHA

RHBDF2

651

Q6PJF5
LVLWLFEYHRSTLQP

PXMP4

166

Q9Y6I8
WLAYIHLIEFNILPS

ZFC3H1

1526

O60293
RPCLISPYHYRLDWL

LMF1

451

Q96S06
HQLYDLLGLVTYLDW

NALCN

876

Q8IZF0