Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	C8	SSPOP FCGBP MUC2 OTOG	9.68e-07	12	127	4	PF08742
Domain	TIL	SSPOP FCGBP MUC2 OTOG	9.68e-07	12	127	4	PF01826
Domain	Unchr_dom_Cys-rich	SSPOP FCGBP MUC2 OTOG	1.39e-06	13	127	4	IPR014853
Domain	C8	SSPOP FCGBP MUC2 OTOG	1.39e-06	13	127	4	SM00832
Domain	TIL_dom	SSPOP FCGBP MUC2 OTOG	1.94e-06	14	127	4	IPR002919
Domain	VWF_type-D	SSPOP FCGBP MUC2 OTOG	3.48e-06	16	127	4	IPR001846
Domain	VWFD	SSPOP FCGBP MUC2 OTOG	3.48e-06	16	127	4	PS51233
Domain	VWD	SSPOP FCGBP MUC2 OTOG	3.48e-06	16	127	4	SM00216
Domain	VWD	SSPOP FCGBP MUC2 OTOG	3.48e-06	16	127	4	PF00094
Domain	VWC_out	SSPOP FCGBP MUC2 OTOG	7.30e-06	19	127	4	SM00215
Domain	EGF-like_dom	FAT4 LAMA4 LAMC3 TENM2 FCGBP EFEMP1 CSPG5 LRP1 C1S OTOG	7.91e-06	249	127	10	IPR000742
Domain	EGF_2	FAT4 LAMC3 SSPOP TENM2 EFEMP1 CSPG5 LRP1 C1S EPHA3 EPHB1	1.36e-05	265	127	10	PS01186
Domain	EGF_1	FAT4 LAMA4 LAMC3 SSPOP TENM2 EFEMP1 CSPG5 LRP1 C1S	6.25e-05	255	127	9	PS00022
Domain	EGF-like_CS	FAT4 LAMA4 LAMC3 TENM2 EFEMP1 CSPG5 LRP1 C1S EPHB1	7.47e-05	261	127	9	IPR013032
Domain	Growth_fac_rcpt_	FAT4 LAMC3 FBXL19 EFEMP1 LRP1 EPHA3 EPHB1	9.58e-05	156	127	7	IPR009030
Domain	-	LAMC3 SSPOP FBXO27 EPHA3 EPHB1	1.39e-04	73	127	5	2.60.120.260
Domain	LDLR_class-A_CS	MFRP SSPOP LRP1 TMPRSS7	1.54e-04	40	127	4	IPR023415
Domain	VWF_dom	SSPOP FCGBP MUC2 OTOG	1.87e-04	42	127	4	IPR001007
Domain	Znf_PHD-finger	KMT2B KAT6A FBXL19 KMT2D NFX1	2.02e-04	79	127	5	IPR019787
Domain	EGF	FAT4 LAMA4 LAMC3 TENM2 FCGBP EFEMP1 CSPG5 LRP1	2.07e-04	235	127	8	SM00181
Domain	EGF_3	FAT4 SSPOP TENM2 EFEMP1 CSPG5 LRP1 C1S OTOG	2.07e-04	235	127	8	PS50026
Domain	Ldl_recept_a	MFRP SSPOP LRP1 TMPRSS7	2.45e-04	45	127	4	PF00057
Domain	-	MFRP SSPOP LRP1 TMPRSS7	2.67e-04	46	127	4	4.10.400.10
Domain	FN3	LRIT2 FLNC SPEG DCC TRIM9 EPHA3 EPHB1	2.75e-04	185	127	7	SM00060
Domain	LDLRA_1	MFRP SSPOP LRP1 TMPRSS7	3.15e-04	48	127	4	PS01209
Domain	LDrepeatLR_classA_rpt	MFRP SSPOP LRP1 TMPRSS7	3.41e-04	49	127	4	IPR002172
Domain	LDLa	MFRP SSPOP LRP1 TMPRSS7	3.41e-04	49	127	4	SM00192
Domain	LDLRA_2	MFRP SSPOP LRP1 TMPRSS7	3.41e-04	49	127	4	PS50068
Domain	FYrich_C	KMT2B KMT2D	4.53e-04	5	127	2	IPR003889
Domain	FYrich_N	KMT2B KMT2D	4.53e-04	5	127	2	IPR003888
Domain	FYRC	KMT2B KMT2D	4.53e-04	5	127	2	SM00542
Domain	FYRN	KMT2B KMT2D	4.53e-04	5	127	2	SM00541
Domain	UMA	UBAP1L MVB12B	4.53e-04	5	127	2	PS51497
Domain	UMA	UBAP1L MVB12B	4.53e-04	5	127	2	IPR023340
Domain	FYRN	KMT2B KMT2D	4.53e-04	5	127	2	PF05964
Domain	FYRC	KMT2B KMT2D	4.53e-04	5	127	2	PF05965
Domain	FYRC	KMT2B KMT2D	4.53e-04	5	127	2	PS51543
Domain	FYRN	KMT2B KMT2D	4.53e-04	5	127	2	PS51542
Domain	Galactose-bd-like	LAMC3 SSPOP FBXO27 EPHA3 EPHB1	4.55e-04	94	127	5	IPR008979
Domain	FN3_dom	LRIT2 FLNC SPEG DCC TRIM9 EPHA3 EPHB1	5.72e-04	209	127	7	IPR003961
Domain	Cys_knot_C	SSPOP MUC2 OTOG	6.33e-04	25	127	3	IPR006207
Domain	CTCK_2	SSPOP MUC2 OTOG	6.33e-04	25	127	3	PS01225
Domain	Occludin_ELL	MARVELD2 ELL	6.76e-04	6	127	2	IPR010844
Domain	ELL/occludin	MARVELD2 ELL	6.76e-04	6	127	2	IPR031176
Domain	Occludin_ELL	MARVELD2 ELL	6.76e-04	6	127	2	PF07303
Domain	EGF_CA	FAT4 TENM2 EFEMP1 LRP1 C1S	1.48e-03	122	127	5	SM00179
Domain	EGF-like_Ca-bd_dom	FAT4 TENM2 EFEMP1 LRP1 C1S	1.59e-03	124	127	5	IPR001881
Domain	VWC	SSPOP FCGBP MUC2	2.18e-03	38	127	3	SM00214
Domain	FN3	LRIT2 SPEG DCC TRIM9 EPHA3 EPHB1	2.41e-03	199	127	6	PS50853
Domain	ZF_CXXC	KMT2B FBXL19	2.42e-03	11	127	2	PS51058
Domain	Znf_CXXC	KMT2B FBXL19	2.42e-03	11	127	2	IPR002857
Domain	zf-CXXC	KMT2B FBXL19	2.42e-03	11	127	2	PF02008
Domain	EGF_CA	FAT4 EFEMP1 LRP1 C1S	2.82e-03	86	127	4	PF07645
Domain	PHD	KMT2B KAT6A FBXL19 KMT2D	3.19e-03	89	127	4	SM00249
Domain	Znf_PHD	KMT2B KAT6A FBXL19 KMT2D	3.45e-03	91	127	4	IPR001965
Domain	RECEPTOR_TYR_KIN_V_2	EPHA3 EPHB1	3.96e-03	14	127	2	PS00791
Domain	RECEPTOR_TYR_KIN_V_1	EPHA3 EPHB1	3.96e-03	14	127	2	PS00790
Domain	Tyr_kinase_rcpt_V_CS	EPHA3 EPHB1	3.96e-03	14	127	2	IPR001426
Domain	EphA2_TM	EPHA3 EPHB1	3.96e-03	14	127	2	PF14575
Domain	Ephrin_rcpt_lig-bd_dom	EPHA3 EPHB1	3.96e-03	14	127	2	IPR001090
Domain	Eph_TM	EPHA3 EPHB1	3.96e-03	14	127	2	IPR027936
Domain	EPH_lbd	EPHA3 EPHB1	3.96e-03	14	127	2	SM00615
Domain	Ephrin_lbd	EPHA3 EPHB1	3.96e-03	14	127	2	PF01404
Domain	Tyr_kinase_ephrin_rcpt	EPHA3 EPHB1	3.96e-03	14	127	2	IPR016257
Domain	EPH_LBD	EPHA3 EPHB1	3.96e-03	14	127	2	PS51550
Domain	ZF_PHD_2	KMT2B KAT6A FBXL19 KMT2D	4.03e-03	95	127	4	PS50016
Domain	ZF_PHD_1	KMT2B KAT6A FBXL19 KMT2D	4.18e-03	96	127	4	PS01359
Domain	EGF_Ca-bd_CS	FAT4 EFEMP1 LRP1 C1S	4.34e-03	97	127	4	IPR018097
Domain	CUB	MFRP C1S TMPRSS7	4.50e-03	49	127	3	PF00431
Domain	EGF_CA	FAT4 EFEMP1 LRP1 C1S	4.67e-03	99	127	4	PS01187
Domain	CUB	MFRP C1S TMPRSS7	4.77e-03	50	127	3	SM00042
Domain	ASX_HYDROXYL	FAT4 EFEMP1 LRP1 C1S	4.84e-03	100	127	4	PS00010
Domain	fn3	SPEG DCC TRIM9 EPHA3 EPHB1	5.02e-03	162	127	5	PF00041
Domain	Post-SET_dom	KMT2B KMT2D	5.17e-03	16	127	2	IPR003616
Domain	PostSET	KMT2B KMT2D	5.17e-03	16	127	2	SM00508
Domain	SEC7	PSD ARFGEF3	5.17e-03	16	127	2	PS50190
Domain	Sec7	PSD ARFGEF3	5.17e-03	16	127	2	SM00222
Domain	Sec7_dom	PSD ARFGEF3	5.17e-03	16	127	2	IPR000904
Domain	POST_SET	KMT2B KMT2D	5.17e-03	16	127	2	PS50868
Domain	-	MFRP C1S TMPRSS7	5.32e-03	52	127	3	2.60.120.290
Domain	FBOX	FBXW9 FBXL19 FBXO27	5.32e-03	52	127	3	SM00256
Domain	CUB	MFRP C1S TMPRSS7	5.61e-03	53	127	3	PS01180
Domain	EGF-type_Asp/Asn_hydroxyl_site	FAT4 EFEMP1 LRP1 C1S	5.94e-03	106	127	4	IPR000152
Domain	CTCK_1	SSPOP MUC2	6.54e-03	18	127	2	PS01185
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FLNC CRYBG2 SHROOM3 ZNF48 KMT2B SPEG TSNARE1 KAT6A SHC1 PER1 LAMC3 IRS1 GRIN2D FBXL19 NPHP4 CCDC88C KMT2D NUAK1 ADAMTS7 NFX1 AKAP13 ULK1 TNFAIP3 KIFC3 ELL IQCE MVB12B	2.71e-14	1105	137	27	35748872
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	SHROOM3 RALGAPB IRS1 MAP3K3 ARFGEF3 FAM171A1 CCDC88C MAP7D1 NKD2 NFATC3 TRIM9 CEP95 AKAP13 FAM53B TNFAIP3 PLCH1 SH3RF3 OTOG	9.12e-09	861	137	18	36931259
Pubmed	Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the Muc2 mucin, is strongly bound to the Fcgbp protein.	FCGBP MUC2	1.54e-05	2	137	2	19432394
Pubmed	Kabuki syndrome stem cell models reveal locus specificity of histone methyltransferase 2D (KMT2D/MLL4).	KMT2B KMT2D	1.54e-05	2	137	2	35640156
Pubmed	Phosphorylation of LRP1: regulation of transport and signal transduction.	SHC1 LRP1	1.54e-05	2	137	2	12069755
Pubmed	The IgGFc-binding protein FCGBP is secreted with all GDPH sequences cleaved but maintained by interfragment disulfide bonds.	FCGBP MUC2	1.54e-05	2	137	2	34126068
Pubmed	Comparison of methylation episignatures in KMT2B- and KMT2D-related human disorders.	KMT2B KMT2D	1.54e-05	2	137	2	35506254
Pubmed	Evidence for a direct interaction between insulin receptor substrate-1 and Shc.	SHC1 IRS1	1.54e-05	2	137	2	9202037
Pubmed	RNF135 promotes cell proliferation and autophagy in lung adenocarcinoma by promoting the phosphorylation of ULK1.	RNF135 ULK1	1.54e-05	2	137	2	38459884
Pubmed	Nonstructural Protein NS1 of Influenza Virus Disrupts Mitochondrial Dynamics and Enhances Mitophagy via ULK1 and BNIP3.	BNIP3 ULK1	1.54e-05	2	137	2	34578425
Pubmed	Exploring the link between germline and somatic genetic alterations in breast carcinogenesis.	EPHA3 EPHB1	4.61e-05	3	137	2	21124932
Pubmed	Complete loss of murine Xin results in a mild cardiac phenotype with altered distribution of intercalated discs.	FLNC XIRP1	4.61e-05	3	137	2	19843512
Pubmed	PTB domains of IRS-1 and Shc have distinct but overlapping binding specificities.	SHC1 IRS1	4.61e-05	3	137	2	7499194
Pubmed	Histone methyltransferase MLL4 controls myofiber identity and muscle performance through MEF2 interaction.	KMT2B KMT2D	4.61e-05	3	137	2	32544095
Pubmed	Filamin C is a highly dynamic protein associated with fast repair of myofibrillar microdamage.	FLNC XIRP1	4.61e-05	3	137	2	27206985
Pubmed	Structure and ligand recognition of the phosphotyrosine binding domain of Shc.	SHC1 IRS1	4.61e-05	3	137	2	8524391
Pubmed	Multiple tumor-suppressor genes on chromosome 3p contribute to head and neck squamous cell carcinoma tumorigenesis.	XIRP1 EPHA3	4.61e-05	3	137	2	20657180
Pubmed	The histone methyltransferase KMT2B is required for RNA polymerase II association and protection from DNA methylation at the MagohB CpG island promoter.	KMT2B KMT2D	4.61e-05	3	137	2	23358417
Pubmed	The deubiquitinating enzyme USP20 stabilizes ULK1 and promotes autophagy initiation.	USP20 ULK1	4.61e-05	3	137	2	29487085
Pubmed	A combined laser microdissection and mass spectrometry approach reveals new disease relevant proteins accumulating in aggregates of filaminopathy patients.	FLNC XIRP1	4.61e-05	3	137	2	23115302
Pubmed	ULK1 promotes mitophagy via phosphorylation and stabilization of BNIP3.	BNIP3 ULK1	4.61e-05	3	137	2	34654847
Pubmed	Aciculin interacts with filamin C and Xin and is essential for myofibril assembly, remodeling and maintenance.	FLNC XIRP1	4.61e-05	3	137	2	24963132
Pubmed	The insulin-like growth factor-1 pathway mediator genes: SHC1 Met300Val shows a protective effect in breast cancer.	SHC1 IRS1	4.61e-05	3	137	2	15308584
Pubmed	Differential involvement of sarcomeric proteins in myofibrillar myopathies: a morphological and immunohistochemical study.	FLNC XIRP1	4.61e-05	3	137	2	19151983
Pubmed	Evidence for a differential interaction of SHC and the insulin receptor substrate-1 (IRS-1) with the insulin-like growth factor-I (IGF-I) receptor in the yeast two-hybrid system.	SHC1 IRS1	4.61e-05	3	137	2	7559507
Pubmed	Identification of the major SHPTP2-binding protein that is tyrosine-phosphorylated in response to insulin.	SHC1 IRS1	4.61e-05	3	137	2	7629070
Pubmed	v-Src induces Shc binding to tyrosine 63 in the cytoplasmic domain of the LDL receptor-related protein 1.	SHC1 LRP1	4.61e-05	3	137	2	12789267
Pubmed	The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS1 and Shc: implications for insulin control of ras signalling.	SHC1 IRS1	4.61e-05	3	137	2	8491186
Pubmed	The clinical phenotype of YWHAE-NUTM2B/E positive pediatric clear cell sarcoma of the kidney.	NUTM2E NUTM2B	4.61e-05	3	137	2	26542179
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	FLNC KCNH7 KMT2B DLGAP4 RALGAPB NCKAP5 GRIN2D CDKL5	5.11e-05	329	137	8	17474147
Pubmed	Crucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation.	KMT2B KMT2D	9.19e-05	4	137	2	19221051
Pubmed	Ten-m2 is required for the generation of binocular visual circuits.	TENM2 EPHB1	9.19e-05	4	137	2	23884953
Pubmed	IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice.	SHC1 IRS1	9.19e-05	4	137	2	12483226
Pubmed	MLL2 is required in oocytes for bulk histone 3 lysine 4 trimethylation and transcriptional silencing.	KMT2B KMT2D	9.19e-05	4	137	2	20808952
Pubmed	Mutations in Mll2, an H3K4 methyltransferase, result in insulin resistance and impaired glucose tolerance in mice.	KMT2B KMT2D	9.19e-05	4	137	2	23826075
Pubmed	Phosphotyrosine-dependent interaction of SHC and insulin receptor substrate 1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain.	SHC1 IRS1	9.19e-05	4	137	2	7537849
Pubmed	Transcriptional Responses in the Murine Spleen after Toxoplasma gondii Infection: Inflammasome and Mucus-Associated Genes.	FCGBP MUC2	9.19e-05	4	137	2	28604600
Pubmed	A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.	KMT2B KMT2D	9.19e-05	4	137	2	23129768
Pubmed	LERK-7: a ligand of the Eph-related kinases is developmentally regulated in the brain.	EPHA3 EPHB1	9.19e-05	4	137	2	9245480
Pubmed	A novel Netrin-1-sensitive mechanism promotes local SNARE-mediated exocytosis during axon branching.	DCC TRIM9	9.19e-05	4	137	2	24778312
Pubmed	EphB1 recruits c-Src and p52Shc to activate MAPK/ERK and promote chemotaxis.	SHC1 EPHB1	9.19e-05	4	137	2	12925710
Pubmed	Platelet-derived growth factor (PDGF)-induced tyrosine phosphorylation of the low density lipoprotein receptor-related protein (LRP). Evidence for integrated co-receptor function betwenn LRP and the PDGF.	SHC1 LRP1	9.19e-05	4	137	2	11854294
Pubmed	SNPs in axon guidance pathway genes and susceptibility for Parkinson's disease in the Korean population.	DCC EPHB1	9.19e-05	4	137	2	21085126
Pubmed	Different levels of the Tripartite motif protein, Anomalies in sensory axon patterning (Asap), regulate distinct axonal projections of Drosophila sensory neurons.	DCC TRIM9	9.19e-05	4	137	2	22084112
Pubmed	TRIM9-dependent ubiquitination of DCC constrains kinase signaling, exocytosis, and axon branching.	DCC TRIM9	9.19e-05	4	137	2	28701345
Pubmed	Evidence for the direct interaction of the insulin-like growth factor I receptor with IRS-1, Shc, and Grb10.	SHC1 IRS1	9.19e-05	4	137	2	8776723
Pubmed	Distinct modes of interaction of SHC and insulin receptor substrate-1 with the insulin receptor NPEY region via non-SH2 domains.	SHC1 IRS1	9.19e-05	4	137	2	7559478
Pubmed	Molecular characterization of a family of ligands for eph-related tyrosine kinase receptors.	EPHA3 EPHB1	9.19e-05	4	137	2	8070404
Pubmed	BNIP3 is degraded by ULK1-dependent autophagy via MTORC1 and AMPK.	BNIP3 ULK1	9.19e-05	4	137	2	23291726
Pubmed	Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.	DLGAP4 DCC TENM2 ARFGEF3 CDKL5 SH3RF3	1.36e-04	197	137	6	36604605
Pubmed	Evolving Catalytic Properties of the MLL Family SET Domain.	KMT2B KMT2D	1.53e-04	5	137	2	26320581
Pubmed	Non-SH2 domains within insulin receptor substrate-1 and SHC mediate their phosphotyrosine-dependent interaction with the NPEY motif of the insulin-like growth factor I receptor.	SHC1 IRS1	1.53e-04	5	137	2	7541045
Pubmed	Unusual splicing events result in distinct Xin isoforms that associate differentially with filamin c and Mena/VASP.	FLNC XIRP1	1.53e-04	5	137	2	16631741
Pubmed	MLL2, Not MLL1, Plays a Major Role in Sustaining MLL-Rearranged Acute Myeloid Leukemia.	KMT2B KMT2D	1.53e-04	5	137	2	28609655
Pubmed	Differential signaling by adaptor molecules LRP1 and ShcA regulates adipogenesis by the insulin-like growth factor-1 receptor.	SHC1 LRP1	1.53e-04	5	137	2	21454706
Pubmed	Characterization of the transforming activity of p80, a hyperphosphorylated protein in a Ki-1 lymphoma cell line with chromosomal translocation t(2;5).	SHC1 IRS1	1.53e-04	5	137	2	8633037
Pubmed	ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK).	SHC1 IRS1	1.53e-04	5	137	2	9174053
Pubmed	pS2/TFF1 interacts directly with the VWFC cysteine-rich domains of mucins.	TFF2 MUC2	1.53e-04	5	137	2	10611155
Pubmed	Nephrocystin-conserved domains involved in targeting to epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity.	FLNC NPHP4	1.53e-04	5	137	2	12006559
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	FAT4 KMT2B IRS1 PIWIL2 SSPOP USP20 TRIM9 CEP95 TRA2A AKAP13 IQCE	1.68e-04	736	137	11	29676528
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SPEG DLGAP4 RALGAPB TENM2 ARFGEF3 MAP7D1 ULK1 CAMTA1	2.21e-04	407	137	8	12693553
Pubmed	New loci associated with central cornea thickness include COL5A1, AKAP13 and AVGR8.	ZNF469 AKAP13	2.29e-04	6	137	2	20719862
Pubmed	Isolation of LERK-5: a ligand of the eph-related receptor tyrosine kinases.	EPHA3 EPHB1	2.29e-04	6	137	2	8559144
Pubmed	Cleavage of TFIIA by Taspase1 activates TRF2-specified mammalian male germ cell programs.	KMT2B KMT2D	2.29e-04	6	137	2	24176642
Pubmed	Biosynthesis of gastrokine-2 in the human gastric mucosa: restricted spatial expression along the antral gland axis and differential interaction with TFF1, TFF2 and mucins.	TFF2 MUC2	2.29e-04	6	137	2	17982272
Pubmed	Growth hormone stimulates the formation of a multiprotein signaling complex involving p130(Cas) and CrkII. Resultant activation of c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK).	SHC1 IRS1	2.29e-04	6	137	2	9837978
Pubmed	Mammalian TRIM67 Functions in Brain Development and Behavior.	DCC TRIM9	2.29e-04	6	137	2	29911180
Pubmed	MLL associates specifically with a subset of transcriptionally active target genes.	KMT2B KMT2D	2.29e-04	6	137	2	16199523
Pubmed	Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases.	KMT2B KMT2D	2.29e-04	6	137	2	17021013
Pubmed	Genome-wide association study of periodontal pathogen colonization.	TENM2 EVX2 CAMTA1	2.48e-04	31	137	3	22699663
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SHROOM3 ZNF280C RGP1 KIAA1614 NUAK1 TRIM9 FAM53B ACAP3 IQCE	2.61e-04	529	137	9	14621295
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	LEMD3 DLGAP4 RALGAPB RGP1 FAM171A1 PLCH1 EPHA3 MVB12B	2.77e-04	421	137	8	36976175
Pubmed	Gene-environment interaction in the etiology of mathematical ability using SNP sets.	MFSD6 NUAK1	3.19e-04	7	137	2	20978832
Pubmed	Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4.	KMT2B KMT2D	3.19e-04	7	137	2	30604749
Pubmed	A new nomenclature for the laminins.	LAMA4 LAMC3	3.19e-04	7	137	2	7921537
Pubmed	Multiple epigenetic maintenance factors implicated by the loss of Mll2 in mouse development.	KMT2B KMT2D	3.19e-04	7	137	2	16540515
Pubmed	Trim9 Deletion Alters the Morphogenesis of Developing and Adult-Born Hippocampal Neurons and Impairs Spatial Learning and Memory.	DCC TRIM9	3.19e-04	7	137	2	27147649
Pubmed	Regulation of transcription by the MLL2 complex and MLL complex-associated AKAP95.	KMT2B KMT2D	3.19e-04	7	137	2	23995757
Pubmed	Interactions between Src homology (SH) 2/SH3 adapter proteins and the guanylnucleotide exchange factor SOS are differentially regulated by insulin and epidermal growth factor.	SHC1 IRS1	3.19e-04	7	137	2	8810325
Pubmed	Human immunodeficiency virus-1 protein Tat induces excitotoxic loss of presynaptic terminals in hippocampal cultures.	GRIN2D LRP1	3.19e-04	7	137	2	23267846
Pubmed	Human immunodeficiency virus protein Tat induces synapse loss via a reversible process that is distinct from cell death.	GRIN2D LRP1	3.19e-04	7	137	2	19036954
Pubmed	ASCOM controls farnesoid X receptor transactivation through its associated histone H3 lysine 4 methyltransferase activity.	KMT2B KMT2D	3.19e-04	7	137	2	19556342
Pubmed	Genetic variation in candidate obesity genes ADRB2, ADRB3, GHRL, HSD11B1, IRS1, IRS2, and SHC1 and risk for breast cancer in the Cancer Prevention Study II.	SHC1 IRS1	3.19e-04	7	137	2	18611262
Pubmed	Mis-expression of L1 on pre-crossing spinal commissural axons disrupts pathfinding at the ventral midline.	DCC EPHB1	4.25e-04	8	137	2	17884558
Pubmed	Comparative analysis of the signaling capabilities of the insulin receptor-related receptor.	SHC1 IRS1	4.25e-04	8	137	2	15629149
Pubmed	RACK1-mediated integration of adhesion and insulin-like growth factor I (IGF-I) signaling and cell migration are defective in cells expressing an IGF-I receptor mutated at tyrosines 1250 and 1251.	SHC1 IRS1	4.25e-04	8	137	2	15611085
Pubmed	Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.	KMT2B KMT2D	4.25e-04	8	137	2	23130995
Pubmed	MicroRNA-124 suppresses the transactivation of nuclear factor of activated T cells by targeting multiple genes and inhibits the proliferation of pulmonary artery smooth muscle cells.	NFATC3 CAMTA1	4.25e-04	8	137	2	23853098
Pubmed	HIV-tat induces formation of an LRP-PSD-95- NMDAR-nNOS complex that promotes apoptosis in neurons and astrocytes.	GRIN2D LRP1	4.25e-04	8	137	2	17360663
Pubmed	The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.	KMT2B KMT2D	4.25e-04	8	137	2	22266653
Pubmed	Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.	B3GNT4 PLB1 SPATA8 U2SURP FBXL19 FAM171A1 KIF19 DGCR8 QSOX2 EPHA3 MVB12B	4.75e-04	832	137	11	36724073
Pubmed	Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.	SHC1 EPHA3 EPHB1	5.31e-04	40	137	3	30898150
Pubmed	Complementary expression of transmembrane ephrins and their receptors in the mouse spinal cord: a possible role in constraining the orientation of longitudinally projecting axons.	DCC EPHB1	5.45e-04	9	137	2	10704386
Pubmed	Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.	KMT2B KMT2D	5.45e-04	9	137	2	22665483
Pubmed	Degenerate PCR-based cloning method for Eph receptors and analysis of their expression in the developing murine central nervous system and vasculature.	EPHA3 EPHB1	5.45e-04	9	137	2	11403717
Pubmed	Kinase independent function of EphB receptors in retinal axon pathfinding to the optic disc from dorsal but not ventral retina.	DCC EPHB1	5.45e-04	9	137	2	10683176
Pubmed	Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression.	KMT2B KMT2D	5.45e-04	9	137	2	16951254
Pubmed	Functional proteomics mapping of a human signaling pathway.	FLNC KMT2B LEMD3 LAMA4 FAM161B KMT2D LRP1 TNFAIP3 ZMYM5	5.81e-04	591	137	9	15231748
Pubmed	DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.	KMT2B FBXL19	6.79e-04	10	137	2	29276034
Pubmed	Structure homology and interaction redundancy for discovering virus-host protein interactions.	SHC1 IRS1	6.79e-04	10	137	2	24008843
Interaction	TOP3B interactions	FLNC CRYBG2 SHROOM3 ZNF48 KMT2B SPEG TSNARE1 KAT6A SHC1 PER1 LAMC3 IRS1 GRIN2D FBXL19 NPHP4 CCDC88C IGF2BP2 KMT2D NUAK1 ADAMTS7 NFX1 AKAP13 ULK1 TNFAIP3 KIFC3 ELL IQCE MVB12B	3.35e-07	1470	134	28	int:TOP3B
Interaction	YWHAG interactions	SHROOM3 ARHGAP23 NHSL2 SPEG RALGAPB SHC1 IRS1 MAP3K3 FAM171A1 CCDC88C MAP7D1 NKD2 NUAK1 NFATC3 CEP95 TRA2A AKAP13 FAM53B ULK1 TNFAIP3 PLCH1 SH3RF3 OTOG	7.72e-06	1248	134	23	int:YWHAG
Interaction	YWHAH interactions	SHROOM3 NHSL2 SPEG RALGAPB IRS1 CHRNA4 MAP3K3 ARFGEF3 FAM171A1 CCDC88C MAP7D1 NKD2 NUAK1 NFATC3 CEP95 AKAP13 FAM53B TNFAIP3 PLCH1 SH3RF3 OTOG	1.23e-05	1102	134	21	int:YWHAH
Interaction	YWHAB interactions	SHROOM3 ARHGAP23 SPEG KAT6A RALGAPB IRS1 MAP3K3 FAM171A1 CCDC88C MAP7D1 NKD2 NUAK1 NFATC3 CEP95 AKAP13 FAM53B TNFAIP3 PLCH1 SH3RF3 OTOG	1.23e-05	1014	134	20	int:YWHAB
Interaction	TTC23L interactions	FAM161B USP20 CCDC24 IQCE	2.49e-05	26	134	4	int:TTC23L
GeneFamily	PHD finger proteins	KMT2B KAT6A FBXL19 KMT2D NFX1	5.51e-05	90	82	5	88
GeneFamily	Zinc fingers CXXC-type	KMT2B FBXL19	1.30e-03	12	82	2	136
GeneFamily	Laminin subunits	LAMA4 LAMC3	1.30e-03	12	82	2	626
GeneFamily	Fibronectin type III domain containing\|Sterile alpha motif domain containing\|EPH receptors	EPHA3 EPHB1	1.78e-03	14	82	2	1095
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PSD ARHGAP23 IRS1 AKAP13 ACAP3	2.45e-03	206	82	5	682
Coexpression	PRC1_BMI_UP.V1_DN	AANAT CRYBG2 MFSD6 LAMC3 DCC INKA2 KMT2D ADAMTS7	6.24e-06	187	136	8	M2730
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FAT4 NHSL2 LAMA4 NKD2 NUAK1 LRP1 ARHGAP28 SH3RF3	2.03e-07	200	137	8	cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FLNC FAT4 LAMC3 NCKAP5 GRIN2D EFEMP1 PLCH1	1.30e-06	177	137	7	1cb78133ac09ea3a3f5b5de07151033998406512
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT4 LAMC3 NCKAP5 GRIN2D DCC EFEMP1 ARHGAP28	1.40e-06	179	137	7	97ba67a856680f24846244c0b92c886cc0e79537
ToppCell	Control-Endothelial-VE_Venous\|Control / Disease state, Lineage and Cell class	ARHGAP23 FAM171A1 EFEMP1 NUAK1 NOSTRIN SH3RF3 C3orf36	2.15e-06	191	137	7	617546cf4883dedf3323e03a53ba5adec334cf8e
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D231\|Adult / Lineage, Cell type, age group and donor	NHSL2 LAMA4 TENM2 NKD2 NUAK1 C1S ARHGAP28	2.30e-06	193	137	7	ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCell	Mesenchymal-matrix_fibroblast_1_cell\|World / Lineage, Cell type, age group and donor	FAT4 NHSL2 LAMA4 TENM2 NKD2 NUAK1 ARHGAP28	2.30e-06	193	137	7	acad568621ed677031797b8c2e34dafea798d681
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FAT4 NHSL2 LAMA4 EFEMP1 NKD2 LRP1 SH3RF3	2.64e-06	197	137	7	0dd71e399f253787fa546a7e90c5373180b89ffd
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NHSL2 LAMA4 NKD2 NUAK1 LRP1 ARHGAP28 SH3RF3	2.91e-06	200	137	7	e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCell	LPS_only-Endothelial-Endothelial-Gen_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	FAT4 LAMA4 NCKAP5 FAM171A1 IGF2BP2 NUAK1 NOSTRIN	2.91e-06	200	137	7	eb94a5111ef0e903ee5be9f7efe571b4e6d5fce1
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FAT4 NHSL2 LAMA4 EFEMP1 LRP1 C1S SH3RF3	2.91e-06	200	137	7	b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCell	Parenchymal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NHSL2 LAMA4 NKD2 NUAK1 LRP1 ARHGAP28 SH3RF3	2.91e-06	200	137	7	cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FAT4 NHSL2 LAMA4 EFEMP1 NKD2 LRP1 C1S	2.91e-06	200	137	7	3dd022e974fec7013ba18f333da63f58fbf2dd7c
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NHSL2 LAMA4 NKD2 NUAK1 LRP1 ARHGAP28 SH3RF3	2.91e-06	200	137	7	311fab076f2ceb258e3970eb21e39344b894042a
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NHSL2 LAMA4 NKD2 NUAK1 LRP1 ARHGAP28 SH3RF3	2.91e-06	200	137	7	34f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FAT4 NHSL2 LAMA4 EFEMP1 LRP1 C1S SH3RF3	2.91e-06	200	137	7	0c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FAT4 LAMA4 IRS1 NKD2 LRP1 SH3RF3 EPHA3	2.91e-06	200	137	7	58b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCell	Club_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	SHROOM3 PRR5L NCKAP5 ARFGEF3 ARHGAP28 ZNF415	9.94e-06	159	137	6	a7bcff268b1962a561fd2848e01ae16565bce895
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SUSD4 KMT2B PSD ZNF280C FAM53B FBXO27	1.15e-05	163	137	6	953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCell	Control\|World / group, cell type (main and fine annotations)	SHROOM3 NCKAP5 TACC2 IQCN ARFGEF3 PLCH1	1.36e-05	168	137	6	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SUSD4 DCC CHRNA4 CSPG5 LRP1 NYAP1	1.71e-05	175	137	6	d67c77eee979ad029e7545f383326f0ff77c6e5f
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SHC1 ARFGEF3 PHKA1 FCGBP CEP95 PLCH1	1.71e-05	175	137	6	dbd9dac129fb6ae5f55e7b96d04b37585458dc4a
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SUSD4 DCC CHRNA4 CSPG5 LRP1 NYAP1	1.71e-05	175	137	6	1d1cdbf3221b03e24eae38afd57cbd6736b37a53
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 NHSL2 LAMC3 LRP1 EPHA3 CREB3L2	1.77e-05	176	137	6	9bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 NHSL2 LAMC3 LRP1 EPHA3 CREB3L2	1.77e-05	176	137	6	3f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCell	metastatic_Lymph_Node-Endothelial_cells\|metastatic_Lymph_Node / Location, Cell class and cell subclass	ARHGAP23 PCDHB7 LAMA4 SYT15 EFEMP1 NOSTRIN	1.83e-05	177	137	6	71bf5d4bc67bda37a0499e5ec01af7dd5254041d
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT4 GRIN2D DCC EFEMP1 NKD2 ARHGAP28	1.83e-05	177	137	6	84116796ca4c7007508c0f1a68a1135c7b922278
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	PRR5L ZNF280C NPHP4 CCDC88C NFX1 TRA2A	1.83e-05	177	137	6	eb0cfe8e9a91910f9979608ed47add48d98ce4dd
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT4 LAMC3 NCKAP5 GRIN2D EFEMP1 ARHGAP28	2.14e-05	182	137	6	7dc61e901428cea04f00ebb0939a44d21a6145c6
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT4 NCKAP5 GRIN2D CHRNA4 EFEMP1 ARHGAP28	2.20e-05	183	137	6	e3ffef2b57dc5b96466dccc9cd54ba326ccf378a
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT4 LAMC3 NCKAP5 GRIN2D EFEMP1 ARHGAP28	2.20e-05	183	137	6	5e361be3ae3fe05098968e58427630127bd12675
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 DCC SSPOP ARFGEF3 PLCH1 OTOG	2.27e-05	184	137	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 DCC SSPOP ARFGEF3 PLCH1 OTOG	2.27e-05	184	137	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 DCC SSPOP ARFGEF3 PLCH1 OTOG	2.27e-05	184	137	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMC7 SPEG ADAMTS7 ARHGAP28 EPHA3 EPHB1	2.27e-05	184	137	6	1c857126c0ea0671f0d60b048efca288d348d653
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FLNC SPEG IRS1 TACC2 TRIM9 SH3RF3	2.34e-05	185	137	6	e58a009aaf342be019a909747b1895d5987d4daf
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	FAT4 NCKAP5 TRIM9 ARHGAP28 EPHA3 EPHB1	2.42e-05	186	137	6	7def03dd856b765bd3f493288641981c4f7fd26e
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FAT4 FAM171A1 NUAK1 NOSTRIN SH3RF3 C3orf36	2.49e-05	187	137	6	e35716f8b482be3bf5ab79f087a9caf67a9d197a
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	NHSL2 LAMA4 DCC NKD2 NUAK1 ARHGAP28	2.49e-05	187	137	6	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D175\|Adult / Lineage, Cell type, age group and donor	NHSL2 LAMA4 NKD2 NUAK1 TRIM9 ARHGAP28	2.49e-05	187	137	6	e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT4 LAMC3 NCKAP5 GRIN2D CHRNA4 EFEMP1	2.49e-05	187	137	6	02105c82a9ba79d2f19e002188377fc3440770c2
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	FAT4 LAMA4 TENM2 NKD2 SH3RF3 EPHA3	2.49e-05	187	137	6	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D175\|Adult / Lineage, Cell type, age group and donor	FLNC ARHGAP23 LAMA4 FAM171A1 SH3RF3 EPHB1	2.49e-05	187	137	6	1e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLNC ARHGAP23 SHC1 LAMA4 EFEMP1 ADAMTS7	2.57e-05	188	137	6	26915db8863f4115b46a81982e187322e21600fd
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLNC ARHGAP23 SHC1 LAMA4 EFEMP1 ADAMTS7	2.57e-05	188	137	6	3f76c0f912f8f023ea425be7f43593b3d7f967e3
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLNC ARHGAP23 SHC1 LAMA4 EFEMP1 ADAMTS7	2.57e-05	188	137	6	61ee7b152745164293d8a44ef91ee2393efbdca5
ToppCell	Control-Endothelial-VE_Venous\|World / Disease state, Lineage and Cell class	ARHGAP23 FAM171A1 EFEMP1 NUAK1 NOSTRIN C3orf36	2.64e-05	189	137	6	f83f7521e377ded1522639e9a35c98b3e2725bac
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	FLNC XIRP1 NCKAP5 TACC2 TENM2 AKAP13	2.64e-05	189	137	6	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	FLNC XIRP1 NCKAP5 TACC2 TENM2 AKAP13	2.72e-05	190	137	6	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	ILEUM-non-inflamed-(8)_Activated_fibroblasts\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	FBXW9 LAMC3 C1S SLC49A3 SH3RF3 IQCE	2.72e-05	190	137	6	39fa110d19c97c7cac99f5fb91b26bc08e2f3b42
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FAT4 NHSL2 LAMA4 NKD2 NUAK1 ARHGAP28	2.80e-05	191	137	6	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT4 SUSD4 NCKAP5 FAM171A1 IGF2BP2 NOSTRIN	2.97e-05	193	137	6	6e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NHSL2 LAMA4 TENM2 NKD2 NUAK1 ARHGAP28	2.97e-05	193	137	6	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NHSL2 LAMA4 TENM2 NKD2 NUAK1 ARHGAP28	2.97e-05	193	137	6	b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NHSL2 LAMA4 EFEMP1 LRP1 C1S EPHA3	3.06e-05	194	137	6	c49f72441b3557e2c3a9c4239e68c0cf0652814b
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PRR5L LAMA4 TENM2 NKD2 NUAK1 ARHGAP28	3.06e-05	194	137	6	35f132cc38ac133be01834ed0946188aa0757eb4
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT4 SUSD4 NCKAP5 FAM171A1 IGF2BP2 NOSTRIN	3.06e-05	194	137	6	0b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAT4 LAMA4 EFEMP1 LRP1 C1S EPHA3	3.15e-05	195	137	6	f54bc4454270ff06e85596f98199372b50d0179f
ToppCell	COVID-19-Heart-Fib_1\|Heart / Disease (COVID-19 only), tissue and cell type	EFEMP1 TRIM9 LRP1 C1S EPHA3 CREB3L2	3.15e-05	195	137	6	f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCell	COVID-19-Fibroblasts-Alveolar_FB\|COVID-19 / group, cell type (main and fine annotations)	NHSL2 LAMA4 IGF2BP2 NKD2 NUAK1 ARHGAP28	3.15e-05	195	137	6	603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NHSL2 LAMA4 EFEMP1 LRP1 C1S EPHA3	3.15e-05	195	137	6	3c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 LAMA4 LAMC3 LRP1 C1S SH3RF3	3.24e-05	196	137	6	a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 LAMA4 LAMC3 LRP1 C1S SH3RF3	3.24e-05	196	137	6	3e6803587d8566fd08cb8b290be3b6461743d79c
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PLB1 SHROOM3 TSNARE1 MARVELD2 KIFC3 CAMTA1	3.33e-05	197	137	6	b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCell	10x3'2.3-week_17-19-Mesenchymal_adipo\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	LAMA4 NCKAP5 TENM2 EFEMP1 LRP1 C1S	3.33e-05	197	137	6	5afddde4e2b5cd55abe11e9b9efae02dbdc3da3a
ToppCell	10x3'2.3-week_17-19-Mesenchymal_adipo-stroma-adipo-CAR\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	LAMA4 NCKAP5 TENM2 EFEMP1 LRP1 C1S	3.33e-05	197	137	6	1baffd087ca194a7355fefbb3bf67befb14fe2de
ToppCell	10x3'2.3-week_17-19-Mesenchymal_adipo-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	LAMA4 NCKAP5 TENM2 EFEMP1 LRP1 C1S	3.33e-05	197	137	6	b9745e382baa2725dfcae060701fb53f6c8a31fa
ToppCell	distal-3-mesenchymal-Fibromyocyte\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	XIRP1 SPEG IRS1 CHRNA4 TRIM9 C1S	3.43e-05	198	137	6	dc93886439a378a0c71e99acb8081bfb6b6d467b
ToppCell	COVID-19-lung-Fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NHSL2 LAMA4 NKD2 LRP1 C1S ARHGAP28	3.43e-05	198	137	6	3ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell	Adult-Mesenchymal\|Adult / Lineage, Cell type, age group and donor	NHSL2 LAMA4 NKD2 NUAK1 C1S ARHGAP28	3.43e-05	198	137	6	26e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCell	COVID-19-lung-Fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	NHSL2 LAMA4 NKD2 NUAK1 C1S ARHGAP28	3.43e-05	198	137	6	df3de77216f5c5d6141ec44d01c56b942f611838
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FAT4 LAMA4 NCKAP5 FAM171A1 IGF2BP2 NOSTRIN	3.63e-05	200	137	6	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	FAT4 LAMA4 NKD2 C1S ARHGAP28 EPHA3	3.63e-05	200	137	6	aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCell	Tracheal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FAT4 LAMC3 NKD2 LRP1 C1S EPHA3	3.63e-05	200	137	6	8ab0051544ea32eb8b3f7f8ba7582deaf8bf26c0
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	FAT4 LAMA4 NKD2 C1S ARHGAP28 EPHA3	3.63e-05	200	137	6	a510deaada669e690329183e18df02870bd204b3
ToppCell	Tracheal-10x3prime_v2-Stromal-Peri/Epineurial_\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP23 NHSL2 TENM2 KIAA1614 SCML1 C1S	3.63e-05	200	137	6	f7c3a8f5ac156c05ad7335d6d142c154c7d86449
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FAT4 LAMA4 NKD2 C1S ARHGAP28 EPHA3	3.63e-05	200	137	6	dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-oligodendrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNC ARHGAP23 SSPOP MAP7D1 FAM53B	1.01e-04	150	137	5	afd651c654e715414eff64cf3a37378d057a56a2
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-5\|TCGA-Colorectal / Sample_Type by Project: Shred V9	TFF2 ARFGEF3 FCGBP KIF19 MUC2	1.25e-04	157	137	5	5fb41af247465aa29aa7b8edd26e3d3794766f80
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NHSL2 KIF19 MARVELD2 NOSTRIN OTOG	1.37e-04	160	137	5	33050dc646762dc7e9dcc4a12c618e1ba1ce5a4d
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DEAF1 KIAA1614 LRP1 ZNF415 CCDC157	1.49e-04	163	137	5	360cd65decda24853124f33a174f5224d7f3ce23
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like-AT1_Progenitor\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DEAF1 KIAA1614 LRP1 ZNF415 CCDC157	1.49e-04	163	137	5	b59d9b4f7c9f4e5e2c7783a49a96729dae3a81e5
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SUSD4 PSD ZNF280C PCDHB7 FAM53B	1.49e-04	163	137	5	132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TSNARE1 IRS1 ARFGEF3 ZNF415 CREB3L2	1.49e-04	163	137	5	cab65dabeea58141c649e4fec5e0123beb3de1b3
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PLB1 LAMA4 DCC RTN2 IQCE	1.49e-04	163	137	5	0ab043b68e8739adcedda01165a3758cd0d22728
ToppCell	Control-Epithelial-Mesothelial\|World / Disease state, Lineage and Cell class	FLNC LAMA4 EFEMP1 C1S NYAP1	1.62e-04	166	137	5	32ebaefa6c074b28193fff764ee7c2c0e9357e20
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNC SUSD4 PCDHB7 ARFGEF3 IGF2BP2	1.76e-04	169	137	5	d382a76d85875663502cc7dde2e3e0682605768e
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FAT4 LAMA4 NKD2 C1S SH3RF3	1.76e-04	169	137	5	c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 ARHGAP23 SPEG ARHGAP28 EPHA3	1.76e-04	169	137	5	87116c33c5ca8cb1862e103e5607b1df4d264569
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	C1orf167 SCML1 TRA2A C1S ELL	1.76e-04	169	137	5	84b898a9fd8ced67c6a501d5cef6416f519902c4
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	FLNC NCKAP5 TENM2 FCGBP INSYN2B	1.81e-04	170	137	5	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	5'-Adult-LargeIntestine-Epithelial-goblet-Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IQCN ARFGEF3 FCGBP KIF19 MUC2	1.86e-04	171	137	5	48125d825ca2d7ef34564250f5b47d2a579e03c9
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ARHGAP23 NHSL2 NUAK1 NOSTRIN C3orf36	1.86e-04	171	137	5	1ae4b6a25bc9c1065cf5d95998ebcc70aee21ab5
ToppCell	COVID-19-kidney-Plasma\|kidney / Disease (COVID-19 only), tissue and cell type	DCC CCDC88C CPNE6 KIF19 CREB3L2	1.86e-04	171	137	5	a59a054b8e119215f24dc5c80ad5a8094b3500f9
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PCDHB7 LAMC3 TRIM9 C1S EPHA3	1.92e-04	172	137	5	1ef243bce63d841c25e4b74d029d1377f84bcc3d
ToppCell	droplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA4 ARHGAP28 NOSTRIN EPHA3 EPHB1	1.92e-04	172	137	5	073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PCDHB7 LAMC3 TRIM9 C1S EPHA3	1.92e-04	172	137	5	ab1c81be29f93ca8920c6ab5ab92f497a9256d3f
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	FLNC EVX2 TTLL6 SLC49A3	1.95e-04	93	137	4	af489f0dd76c3c1a84d164283149f550a7ece91c
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Coch_(Coch)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	FLNC EVX2 TTLL6 SLC49A3	1.95e-04	93	137	4	c1d0afcfa37c2dcbb12189b4ce56ae7c4bb7ba30
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Coch_(Coch)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	FLNC EVX2 TTLL6 SLC49A3	1.95e-04	93	137	4	0ea74c2820372d60d3804bf2c8bb0d03733dff98
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th\|T/NK_cells / Location, Cell class and cell subclass	CRYBG2 SHC1 PER1 TNFAIP3 MPG	1.97e-04	173	137	5	42c911ed16fabdabef063830e8407192d8bde950
Computational	Genes in the cancer module 257.	DLGAP4 SHC1 KMT2D LRP1 TRA2A DGCR8 ELL	9.44e-05	156	74	7	MODULE_257
Drug	ICI 182,780; Down 200; 0.01uM; PC3; HT_HG-U133A	MFSD6 PER1 RGP1 USP20 HROB NFATC3 MRPS11 FAM53B TNFAIP3	2.71e-06	198	134	9	1238_DN
Drug	Metaraminol bitartrate [33402-03-8]; Down 200; 8.6uM; PC3; HT_HG-U133A	KMT2B KAT6A LAMA4 LAMC3 RTN2 USP20 TRA2A ZNF415	2.08e-05	195	134	8	3669_DN
Drug	0198306-0000 [212631-61-3]; Up 200; 10uM; PC3; HT_HG-U133A	B3GNT4 CRYBG2 HROB CSPG5 MRPS11 DGCR8 KIFC3 IQCE	2.16e-05	196	134	8	7102_UP
Drug	Oxyphenbutazone [129-20-4]; Down 200; 12.4uM; PC3; HT_HG-U133A	U2SURP HROB NFX1 MRPS11 LRP1 AKAP13 PLCH1 ZMYM5	2.24e-05	197	134	8	4506_DN
Drug	Dextromethorphan hydrobromide monohydrate [6700-34-1]; Up 200; 10.8uM; PC3; HT_HG-U133A	B3GNT4 CRYBG2 PER1 CHRNA4 NFATC3 NFX1 TRA2A EPHB1	2.32e-05	198	134	8	6300_UP
Drug	Guanabenz acetate [23256-50-0]; Down 200; 13.8uM; MCF7; HT_HG-U133A	B3GNT4 KMT2B RTN2 USP20 NFATC3 PLCH1 MUC2 EPHA3	2.32e-05	198	134	8	5703_DN
Drug	Piperidolate hydrochloride [129-77-1]; Up 200; 11.2uM; HL60; HT_HG-U133A	CRYBG2 TMC7 MFSD6 PER1 LAMC3 CHRNA4 INKA2 PLCH1	2.32e-05	198	134	8	6129_UP
Drug	Moxisylyte hydrochoride [964-52-3]; Down 200; 12.6uM; MCF7; HT_HG-U133A	U2SURP CCDC88C MAP7D1 EFEMP1 CSPG5 NFX1 DGCR8 PLCH1	2.50e-05	200	134	8	7015_DN
Disease	cortical thickness	SHROOM3 KMT2B LAMC3 NCKAP5 TACC2 TENM2 KIAA1614 ZNF469 NUAK1 ADAMTS7 LRP1 FAM53B CAMTA1 PLCH1 PCCB SH3RF3 ELL EPHA3	2.76e-06	1113	133	18	EFO_0004840
Disease	neuroimaging measurement	SHROOM3 KMT2B NCKAP5 TACC2 DCC RGP1 CCDC88C ZNF469 NUAK1 FAM53B NOSTRIN CAMTA1 PLCH1 SH3RF3 QSOX2 EPHA3	2.66e-05	1069	133	16	EFO_0004346
Disease	neuroimaging measurement, brain volume measurement	NCKAP5 DCC RGP1 CCDC88C NUAK1 FAM53B NOSTRIN EPHA3	4.86e-05	286	133	8	EFO_0004346, EFO_0006930
Disease	brain measurement, neuroimaging measurement	RNF135 NCKAP5 DCC RGP1 CCDC88C NUAK1 FAM53B NOSTRIN SH3RF3 EPHA3	2.03e-04	550	133	10	EFO_0004346, EFO_0004464
Disease	Clear cell sarcoma of kidney	NUTM2E NUTM2B	2.99e-04	6	133	2	C0334488
Disease	smoking status measurement, triglyceride measurement	B3GNT4 DGCR8	2.99e-04	6	133	2	EFO_0004530, EFO_0006527
Disease	complement C1r subcomponent measurement	IGHD C1S	4.17e-04	7	133	2	EFO_0008090
Disease	lung volume	IGF2BP2 EFEMP1	5.55e-04	8	133	2	EFO_0600046
Disease	triacylglycerol 58:6 measurement	PRR5L TENM2	5.55e-04	8	133	2	EFO_0010440
Disease	tyrosine-protein phosphatase non-receptor type 4 measurement	IGHD C1S	7.11e-04	9	133	2	EFO_0802172
Disease	Microphthalmos	MFRP KMT2D	1.08e-03	11	133	2	C0026010
Disease	metabolite measurement, body weight gain	TACC2 KIF19	1.29e-03	12	133	2	EFO_0004566, EFO_0004725
Disease	sexual dimorphism measurement	B3GNT4 KMT2B DLGAP4 RNF135 RGP1 MAP3K3 HROB IGF2BP2 EFEMP1 TRA2A FAM53B NOSTRIN QSOX2	1.51e-03	1106	133	13	EFO_0021796
Disease	esophageal cancer (is_implicated_in)	DCC TNFAIP3	1.52e-03	13	133	2	DOID:5041 (is_implicated_in)
Disease	beta-amyloid 1-42 measurement, cerebrospinal fluid biomarker measurement	FAT4 SPATA8	1.77e-03	14	133	2	EFO_0004670, EFO_0006794
Disease	lymphocyte measurement	NFATC3 FAM53B ULK1 CCDC157	1.97e-03	117	133	4	EFO_0803546
Disease	white matter microstructure measurement	KMT2B NCKAP5 DCC TENM2 KIAA1614 NUAK1 CCDC157	2.00e-03	390	133	7	EFO_0005674
Disease	Lymphoma, Follicular, Grade 2	KMT2D TNFAIP3	2.04e-03	15	133	2	C1956132
Disease	Lymphoma, Follicular, Grade 3	KMT2D TNFAIP3	2.04e-03	15	133	2	C1956131
Disease	Lymphoma, Follicular, Grade 1	KMT2D TNFAIP3	2.04e-03	15	133	2	C1956130
Disease	Lymphoma, Large-Cell, Follicular	KMT2D TNFAIP3	2.04e-03	15	133	2	C0079745
Disease	Lymphoma, Small Cleaved-Cell, Follicular	KMT2D TNFAIP3	2.04e-03	15	133	2	C0079765
Disease	Lymphoma, Mixed-Cell, Follicular	KMT2D TNFAIP3	2.04e-03	15	133	2	C0079758
Disease	brain connectivity measurement	NCKAP5 KIAA1614 CCDC88C NUAK1 FAM53B SH3RF3 EPHA3	2.30e-03	400	133	7	EFO_0005210
Disease	Dystonia, Limb	KMT2B CHRNA4	2.62e-03	17	133	2	C0751093
Disease	Dystonia, Diurnal	KMT2B CHRNA4	2.62e-03	17	133	2	C0393610
Disease	hypertension, white matter hyperintensity measurement	DCC CCDC88C EFEMP1	2.79e-03	62	133	3	EFO_0000537, EFO_0005665
Disease	Dystonia, Paroxysmal	KMT2B CHRNA4	2.94e-03	18	133	2	C0393588
Disease	reaction time measurement	KCNH7 ARHGAP23 NCKAP5 TACC2 DCC TENM2 FAM171A1 KMT2D CAMTA1	3.04e-03	658	133	9	EFO_0008393
Disease	cortical surface area measurement	SHROOM3 LAMC3 NCKAP5 RGP1 TENM2 KIAA1614 CCDC88C ZNF469 NUAK1 ADAMTS7 ARHGAP28 SH3RF3 EPHA3 EPHB1	3.06e-03	1345	133	14	EFO_0010736
Disease	Lymphoma, Follicular	KMT2D TNFAIP3	3.63e-03	20	133	2	C0024301
Disease	blood urea nitrogen measurement	SHROOM3 KIAA1614 CDKL5 NFATC3 AKAP13 FAM53B PCCB	4.50e-03	452	133	7	EFO_0004741

Protein segments in the cluster

Peptide	Gene	Start	Entry
ASRNTHSAELPPPDQ	CHRNA4	511	P43681
PPSQLCTAPASSHER	AKAP2	291	Q9Y2D5
DQGPRAHSSPEPRAC	C1orf167	1281	Q5SNV9
QNPRIHCPASEEPST	CAMTA1	1176	Q9Y6Y1
TDCAQPSRPHGSPSR	ELL	431	P55199
PRAQLPDCAPATHAT	ELL	466	P55199
CNTPRTSSPHARALA	CSPG5	491	O95196
ENSQHPARLSPRLPS	EVX2	41	Q03828
SLSHSACPTPNPLSR	FAT4	4686	Q6V0I7
NTPRPRNPSICSADH	FAT4	4796	Q6V0I7
RQPSSQDPPDASHCE	AKAP13	696	Q12802
QKCLRPHSSPRAPTA	ACAP3	536	Q96P50
LIDPNCSGHSPRTAR	DGCR8	86	Q8WYQ5
EQRRSPPACSQHTPP	C3orf36	81	Q3SXR2
RQPCTSPSRQPCSQP	CCDC157	691	Q569K6
RSLPDCTPHPNSISI	DLGAP4	731	Q9Y2H0
ALRPNTTRPCNTHPC	ADAMTS7	1556	Q9UKP4
RSSQSLHCLSPRQPN	CPNE6	321	O95741
PRVLNPSQAFSSCHP	FBXL19	261	Q6PCT2
LQNHTEGSRPPACPR	QSOX2	176	Q6ZRP7
HPTASRTGTPRQTCP	IQCN	406	Q9H0B3
SQRHPPCLSQRPLAA	IQCN	671	Q9H0B3
AEPVRSHPPACLASS	IQCE	361	Q6IPM2
AQELPAPTPSSRHCE	IQCE	481	Q6IPM2
HLDRRNSPPNSLTPC	LEMD3	771	Q9Y2U8
CGRVPPPTLNTNASH	MFRP	216	Q9BY79
HCPSNSRSPAEASPI	EPHB1	286	P54762
FLPQRSHPANPTCVT	FAM189A1	211	O60320
PDQPSSLHVRPQTNC	DCC	726	P43146
PTDPPRTICTRRHDN	FBXW9	416	Q5XUX1
DAPSEPAASPHQRRS	FAM171A1	841	Q5VUB5
PANAHSRPARSLQPQ	IL17REL	311	Q6ZVW7
LAPLPRTQPHQSCAQ	INKA2	116	Q9NTI7
LHRRKAPSCTPAAPQ	LRIT2	501	A6NDA9
HPQPEDSSPSALQRA	KCNH7	1001	Q9NS40
SRPSFNLLDSPHPRQ	PHKA1	726	P46020
ESLACRPPSHPCANN	LRP1	1141	Q07954
RPPSHPCANNTSVCL	LRP1	1146	Q07954
SHQPHPLDSRTPCRT	KIAA1614	731	Q5VZ46
RNSPGSSQHPESPRL	LBHD1	16	Q9BQE6
QSPAPPSSHSLARER	CCDC88C	1846	Q9P219
HNGNPSAPPSKRQCR	FAM53B	101	Q14153
PHRPDSPLFNSRCSS	PER1	966	O15534
STNPEPCSLNPHRRS	MUC2	1031	Q02817
RSPFPVHVSEACNPN	FLNC	461	Q14315
RNYSSPPPCHLSRQV	NFX1	46	Q12986
RCSSLNNLPSNIPRP	FAM161B	131	Q96MY7
ANLRHPQRPCDAATT	FAM161B	406	Q96MY7
KAHLPRPRTPNSSCS	HROB	311	Q8N3J3
QAPQAPRSRACEPST	KMT2B	201	Q9UMN6
SSPSPPQRAQRGDHS	IGF2BP2	161	Q9Y6M1
HSSPSVRCPSQLQPA	IRS1	916	P35568
PAGTRTPQRRCSSHE	KIF25-AS1	166	Q9Y6Z4
VPCETHSDPSRNQPS	MFSD6	741	Q6ZSS7
SAHVRRPSTDPQPCS	NKD2	216	Q969F2
SAAARLPPSPTRCQQ	MVB12B	301	Q9H7P6
QLAASPRSPTQHCLA	NPHP4	506	O75161
PRSPTQHCLARPTSQ	NPHP4	511	O75161
PPHRQCSSEPNITDN	PRR5L	331	Q6MZQ0
RPPSPTLQHAASEDN	KIF19	831	Q2TAC6
SSQDPAPVRECHDPS	PCCB	281	P05166
LPHDSLPANSQPSRR	KAT6A	851	Q92794
QNSSAPCTEPLPRAA	PCDHB7	566	Q9Y5E2
PNASPHDREEACSPQ	BSND	211	Q8WZ55
SSHCDSPPRSQTPQD	BNIP3	61	Q12983
PRHSRCPPNHTVSSA	B3GNT4	71	Q9C0J1
VQEASVQPPCRASHP	DEAF1	376	O75398
RSPANCPLSCPANSR	FCGBP	736	Q9Y6R7
LTAAVSNCPRQHQPP	ARFGEF3	1461	Q5TH69
PSRDLHPARPTQVSC	CRYBG2	856	Q8N1P7
SVTCTLNHPSLPPQR	IGHD	246	P01880
RLCGQRSSNNPHSPI	C1S	81	P09871
HSSSDAAQAPCPRER	MPG	46	P29372
ATASSCNSPFPQRPR	CEP95	346	Q96GE4
PLCSAQRHTPQSPFT	C17orf80	431	Q9BSJ5
ACTRPPSSPRNVISN	EPHA3	321	P29320
PARPNHRSPLNSCKD	MARVELD2	121	Q8N4S9
RTHPSAAVPVCPRSA	MAP7D1	351	Q3KQU3
ARSCQSPARNARPCP	FBXO27	86	Q8NI29
CLDLNSPTSPTPTRH	CDKL5	521	O76039
PSCVSPNHRQRPLGS	CCDC24	226	Q8N4L8
QTHSPSRAAPRAPSA	CREB3L2	231	Q70SY1
QPPEPRSRHLSVSSQ	MAP3K3	156	Q99759
LPERNTPRNSHCHLS	LAMA4	1446	Q16363
TPRNSHCHLSNSPRA	LAMA4	1451	Q16363
AELEQRPQPSHPCSN	NOSTRIN	371	Q8IVI9
QLSQESPRTPTHRPA	OTOG	1496	Q6ZRI0
LHTPRPCSQPRDALS	NYAP1	741	Q6ZVC0
AEALHRTSPTPNSCP	NUTM2B	46	A6NNL0
AEALHRTSPTPNSCP	NUTM2E	46	B1AL46
PQRIPSNPSHRIQCA	EFEMP1	146	Q12805
RSVSEPRDQHPQPSL	RTN2	91	O75298
SSCPLPDQSHPALRR	RNF135	236	Q8IUD6
RENNSPSNLPRPSFC	SCML1	146	Q9UN30
AASSGQRDRPCQPHA	SYT15	51	Q9BQS2
CQPHARTQLSRPPAV	SYT15	61	Q9BQS2
SSQPRAQRHSSEPRP	PSD	1001	A5PKW4
PESPSCQRRHTLPAS	AANAT	21	Q16613
HQSRQRSCVDPPPKN	SSPOP	2576	A2VEC9
QSHRSRACSRPPTPE	SSPOP	3491	A2VEC9
SPEAVIQTRCPAHAP	NCKAP5	1011	O14513
CPEALQSPGRTQHPS	NCKAP5	1421	O14513
PRSSIQHARPLPQDS	NHSL2	906	Q5HYW2
CQFHASESRVALPPP	RGP1	51	Q92546
PSFRGQSPIHPSQCQ	PIWIL2	6	Q8TC59
EPACQTPQPSARAHS	KIFC3	791	Q9BVG8
VSSVDRQPPHSRPCL	FAM90A26	356	D6RGX4
DHQRQASRTPCPRPP	SHROOM3	1321	Q8TF72
NVTVPNTTCHLPRPD	SLC5A9	251	Q2M3M2
RQQPSTPRCCLAPAS	THNSL2	406	Q86YJ6
TNRRSQIHAPAPAPN	TENM2	276	Q9NT68
PPDPARVTSHSLSCR	NUAK1	506	O60285
PQAATSAHPSSREPR	SPSB3	331	Q6PJ21
SAHPSSREPRPCQRK	SPSB3	336	Q6PJ21
PCRDRAPSALHPTSV	PLB1	716	Q6P1J6
RESLCDSPHQNLSRP	U2SURP	61	O15042
ACHRATPRAQGPAAT	SLC49A3	511	Q6UXD7
TDNTPIPHNGCRPRK	MRPS11	176	P82912
RVRAQPSGPSQPHVC	ZNF48	531	Q96MX3
RHFPCPSPESKLQNR	TSNARE1	41	Q96NA8
PPSCHQRSKSDPSRL	TNFAIP3	556	P21580
AQPAATPTSPHRRTQ	SPEG	326	Q15772
PQPACNTSSFRQHGP	TMPRSS7	521	Q7RTY8
QNSPSRLPATSLRPH	SH3RF3	631	Q8TEJ3
PSFQRLPCPRTSSRH	SPATA8	21	Q6RVD6
QPPNAESRCAPRAAA	ARHGAP28	21	Q9P2N2
SQPPRRSAASRLHQC	ARHGAP23	1476	Q9P227
RRHTGSRANPDPNTC	TRA2A	106	Q13595
PPRCQESTHPASDNP	SUSD4	446	Q5VX71
PSPCQCSRLSPHNRT	TFF2	26	Q03403
PHPAQTQRPSSDSGC	NFATC3	721	Q12968
HVPRSTCAPSPQREV	TACC2	1626	O95359
SCPSAALGRRPQSPQ	TPRXL	236	Q17RH7
ALGRRPQSPQSSHCA	TPRXL	241	Q17RH7
VTPSPRQALHPCSDS	nan	106	A1L4Q6
ATPAQLDPRPCRSHA	TTLL6	801	Q8N841
PQSAAVSTTPPHNRR	RALGAPB	371	Q86X10
DNDAHLRSSSRPCSP	USP20	381	Q9Y2K6
RNKPSAPTPAVNRHS	PLCH1	1616	Q4KWH8
EPPSQRRTCQATVPH	ZNF469	1576	Q96JG9
PSPACVSNTHPSRRS	ZNF469	1851	Q96JG9
THLSPALAPVPRNSC	TRIM9	111	Q9C026
HRALSLCPSPAQSPR	UBAP1L	181	F5GYI3
GHPACPLVSRSRNSP	ZMYM5	36	Q9UJ78
HCNLRLPDSNDSPAS	ZNF415	71	Q09FC8
PCSQHTPEISSENRP	ZNF792	596	Q3KQV3
SQRCRDPPSNPVAAS	ZNF280C	91	Q8ND82
PLARCPSGHSQPSLQ	XIRP1	1386	Q702N8
AARPTAPNAQTPSHL	SHC1	376	P29353
QASPPQPSHGLQSCR	ULK1	586	O75385
TCRPSPRPFRASNSN	TMC7	586	Q7Z402
PNCPGSNHLPSSLSR	INSYN2B	371	A6NMK8
SHLSPQSEEPCLSPR	KMT2D	831	O14686
RCRPGTFNLQPHNPA	LAMC3	461	Q9Y6N6
PCRSQLNRTHSPPPD	GRIN2D	461	O15399