Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionL-amino acid transmembrane transporter activity

SLC7A9 SLC38A4 SLC17A7 SLC17A8 SLC36A2

6.13e-0671735GO:0015179
GeneOntologyMolecularFunctionsodium:phosphate symporter activity

SLC17A4 SLC17A7 SLC17A8

1.01e-0512733GO:0005436
GeneOntologyMolecularFunctiontransporter activity

SLC7A9 KCNK18 SLC26A3 HTR1B SLC2A6 SLC38A4 SLC17A4 SLC17A7 SLC17A8 PITPNC1 SLC14A2 ABCA8 SLC36A2 CLCC1 RYR3 ITPR3

1.31e-0512897316GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC7A9 KCNK18 SLC26A3 HTR1B SLC2A6 SLC38A4 SLC17A4 SLC17A7 SLC17A8 SLC14A2 ABCA8 SLC36A2 CLCC1 RYR3 ITPR3

1.95e-0511807315GO:0022857
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH12 DNAH7 DNAH1

3.68e-0518733GO:0008569
GeneOntologyMolecularFunctionL-glutamate uniporter activity

SLC17A7 SLC17A8

3.95e-053732GO:0140788
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC7A9 SLC38A4 SLC17A7 SLC17A8 SLC36A2

4.13e-05105735GO:0015171
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC38A4 SLC17A4 SLC17A7 SLC17A8 SLC36A2

7.51e-05119735GO:0015294
GeneOntologyMolecularFunctionphosphate transmembrane transporter activity

SLC17A4 SLC17A7 SLC17A8

8.98e-0524733GO:0005315
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

KCNK18 SLC26A3 HTR1B SLC38A4 SLC17A4 SLC17A7 SLC17A8 SLC36A2 CLCC1 RYR3 ITPR3

9.12e-057587311GO:0015318
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC7A9 SLC26A3 SLC2A6 SLC38A4 SLC17A7 SLC17A8 SLC36A2

9.71e-05293737GO:0008514
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC7A9 SLC26A3 SLC38A4 SLC17A4 SLC17A7 SLC17A8 SLC36A2

1.03e-04296737GO:0015291
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC7A9 SLC26A3 SLC38A4 SLC17A7 SLC17A8 SLC36A2

1.10e-04207736GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC7A9 SLC26A3 SLC38A4 SLC17A7 SLC17A8 SLC36A2

1.13e-04208736GO:0005342
GeneOntologyMolecularFunctionmembrane potential driven uniporter activity

SLC17A7 SLC17A8

1.31e-045732GO:0022810
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

KCNK18 SLC26A3 HTR1B SLC38A4 SLC17A4 SLC17A7 SLC17A8 SLC36A2 CLCC1 RYR3 ITPR3

1.36e-047937311GO:0015075
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH12 DNAH7 DNAH1

1.44e-0428733GO:0051959
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC38A4 SLC17A4 SLC17A7 SLC17A8

2.21e-0481734GO:0015370
GeneOntologyMolecularFunctionsymporter activity

SLC38A4 SLC17A4 SLC17A7 SLC17A8 SLC36A2

2.23e-04150735GO:0015293
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

KCNK18 HTR1B SLC38A4 SLC17A4 SLC17A7 SLC17A8 RYR3 ITPR3

2.91e-04465738GO:0046873
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH12 DNAH7 DNAH1

3.33e-0437733GO:0045505
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC7A9 SLC26A3 SLC38A4 SLC17A4 SLC17A7 SLC17A8 ABCA8 SLC36A2

3.45e-04477738GO:0022804
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC26A3 SLC17A4 SLC17A7 SLC17A8 CLCC1

4.08e-04171735GO:0015103
GeneOntologyMolecularFunctionneutral L-amino acid transmembrane transporter activity

SLC7A9 SLC38A4 SLC36A2

4.52e-0441733GO:0015175
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

KCNK18 HTR1B SLC38A4 SLC17A4 SLC17A7 SLC17A8 SLC36A2 RYR3 ITPR3

4.53e-04627739GO:0022890
GeneOntologyMolecularFunctionuniporter activity

SLC17A7 SLC17A8

5.82e-0410732GO:0015292
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

KCNK18 HTR1B SLC38A4 SLC17A4 SLC17A7 SLC17A8 SLC36A2 RYR3 ITPR3

6.84e-04664739GO:0008324
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC26A3 SLC38A4 SLC17A4 SLC17A7 SLC17A8 SLC36A2

8.15e-04301736GO:0022853
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

SLC26A3 SLC17A7 SLC17A8 CLCC1

1.14e-03125734GO:0015108
GeneOntologyMolecularFunctionL-glutamate transmembrane transporter activity

SLC17A7 SLC17A8

1.34e-0315732GO:0005313
GeneOntologyMolecularFunctionmonoatomic ion channel activity

KCNK18 HTR1B SLC17A7 SLC17A8 CLCC1 RYR3 ITPR3

1.43e-03459737GO:0005216
GeneOntologyMolecularFunctionalanine transmembrane transporter activity

SLC38A4 SLC36A2

1.53e-0316732GO:0022858
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

RYR3 ITPR3

1.94e-0318732GO:0015278
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH12 DNAH7 DNAH1

2.15e-0370733GO:0003777
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC26A3 SLC17A7 SLC17A8 CLCC1

2.28e-03151734GO:0008509
GeneOntologyMolecularFunctionbasic amino acid transmembrane transporter activity

SLC7A9 SLC38A4

2.40e-0320732GO:0015174
GeneOntologyMolecularFunctionacidic amino acid transmembrane transporter activity

SLC17A7 SLC17A8

2.40e-0320732GO:0015172
GeneOntologyMolecularFunctionneurotransmitter transmembrane transporter activity

SLC17A7 SLC17A8

2.65e-0321732GO:0005326
GeneOntologyMolecularFunctionchannel activity

KCNK18 HTR1B SLC17A7 SLC17A8 CLCC1 RYR3 ITPR3

3.04e-03525737GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

KCNK18 HTR1B SLC17A7 SLC17A8 CLCC1 RYR3 ITPR3

3.07e-03526737GO:0022803
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC38A4 SLC17A4 SLC17A7 SLC17A8

3.57e-03171734GO:0015081
GeneOntologyMolecularFunctionchloride channel activity

SLC17A7 SLC17A8 CLCC1

3.86e-0386733GO:0005254
GeneOntologyMolecularFunctionamino acid:monoatomic cation symporter activity

SLC38A4 SLC36A2

5.02e-0329732GO:0005416
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

KCNK18 SLC17A7 RYR3 ITPR3

5.48e-03193734GO:0015276
GeneOntologyMolecularFunctionligand-gated calcium channel activity

RYR3 ITPR3

5.72e-0331732GO:0099604
GeneOntologyMolecularFunctionligand-gated channel activity

KCNK18 SLC17A7 RYR3 ITPR3

5.89e-03197734GO:0022834
GeneOntologyMolecularFunctionmonoatomic anion channel activity

SLC17A7 SLC17A8 CLCC1

6.38e-03103733GO:0005253
GeneOntologyMolecularFunctionsteroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

AKR1B10 NSDHL

6.47e-0333732GO:0033764
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

RYR3 ITPR3

6.47e-0333732GO:0005217
GeneOntologyMolecularFunctiongated channel activity

KCNK18 HTR1B SLC17A7 RYR3 ITPR3

7.55e-03334735GO:0022836
GeneOntologyMolecularFunctionsteroid dehydrogenase activity

AKR1B10 NSDHL

8.95e-0339732GO:0016229
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNAH12 DNAH7 DNAH1

9.27e-03118733GO:0003774
GeneOntologyBiologicalProcesssodium-dependent phosphate transport

SLC17A4 SLC17A7 SLC17A8

1.24e-0513743GO:0044341
GeneOntologyBiologicalProcessL-alpha-amino acid transmembrane transport

SLC7A9 SLC38A4 SLC17A7 SLC17A8 SLC36A2

1.52e-0587745GO:1902475
GeneOntologyBiologicalProcessL-amino acid transport

SLC7A9 SLC38A4 SLC17A7 SLC17A8 SLC36A2

4.33e-05108745GO:0015807
GeneOntologyBiologicalProcessamino acid transmembrane transport

SLC7A9 SLC38A4 SLC17A7 SLC17A8 SLC36A2

7.17e-05120745GO:0003333
GeneOntologyBiologicalProcessamino acid transport

SLC7A9 HTR1B SLC38A4 SLC17A7 SLC17A8 SLC36A2

7.18e-05195746GO:0006865
GeneOntologyBiologicalProcessorganic anion transport

SLC7A9 SLC26A3 HTR1B SLC2A6 SLC38A4 SLC17A4 SLC17A7 SLC17A8 SLC36A2

9.20e-05515749GO:0015711
GeneOntologyBiologicalProcessphosphate ion transport

SLC17A4 SLC17A7 SLC17A8

1.85e-0431743GO:0006817
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

KCNK18 SLC26A3 CD19 SLC38A4 SLC17A4 SLC17A7 SLC17A8 SLC36A2 CLCC1 RYR3 GP1BA ITPR3

2.51e-0410177412GO:0098660
GeneOntologyBiologicalProcesscarboxylic acid transmembrane transport

SLC7A9 SLC38A4 SLC17A7 SLC17A8 SLC36A2

3.01e-04163745GO:1905039
GeneOntologyBiologicalProcessmaintenance of location in cell

CD19 SLC17A7 GAA RYR3 GP1BA ITPR3

3.36e-04259746GO:0051651
GeneOntologyBiologicalProcessorganic acid transmembrane transport

SLC7A9 SLC38A4 SLC17A7 SLC17A8 SLC36A2

3.36e-04167745GO:1903825
GeneOntologyBiologicalProcesscellular response to magnesium ion

SLFN14 RYR3

3.51e-048742GO:0071286
GeneOntologyBiologicalProcessinorganic anion transport

SLC26A3 SLC17A4 SLC17A7 SLC17A8 CLCC1

4.74e-04180745GO:0015698
GeneOntologyBiologicalProcessmonoatomic anion transport

SLC26A3 SLC17A4 SLC17A7 SLC17A8 CLCC1

5.11e-04183745GO:0006820
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

KCNK18 SLC26A3 CD19 SLC38A4 SLC17A4 SLC17A7 SLC17A8 SLC36A2 CLCC1 RYR3 GP1BA ITPR3

5.76e-0411157412GO:0034220
GeneOntologyBiologicalProcesscarboxylic acid transport

SLC7A9 SLC26A3 HTR1B SLC38A4 SLC17A7 SLC17A8 SLC36A2

6.67e-04410747GO:0046942
GeneOntologyBiologicalProcesssensory perception of bitter taste

RTP1 TAS2R41 ITPR3

6.83e-0448743GO:0050913
GeneOntologyBiologicalProcessneurotransmitter loading into synaptic vesicle

SLC17A7 SLC17A8

6.84e-0411742GO:0098700
GeneOntologyBiologicalProcesssphingomyelin biosynthetic process

ORMDL1 ABCA8

6.84e-0411742GO:0006686
GeneOntologyBiologicalProcessL-alanine transport

SLC38A4 SLC36A2

6.84e-0411742GO:0015808
GeneOntologyBiologicalProcessorganic acid transport

SLC7A9 SLC26A3 HTR1B SLC38A4 SLC17A7 SLC17A8 SLC36A2

6.86e-04412747GO:0015849
GeneOntologyBiologicalProcesschloride transmembrane transport

SLC26A3 SLC17A7 SLC17A8 CLCC1

7.08e-04112744GO:1902476
GeneOntologyBiologicalProcesscellular homeostasis

SLC26A3 ORMDL1 HTR1B CD19 SLC17A7 GCKR GAA RYR3 DMXL1 GP1BA ITPR3

7.13e-049817411GO:0019725
GeneOntologyCellularComponentinner dynein arm

DNAH12 DNAH7 DNAH1

5.23e-0610753GO:0036156
GeneOntologyCellularComponentaxonemal dynein complex

DNAH12 DNAH7 DNAH1

9.64e-0525753GO:0005858
GeneOntologyCellularComponentCul3-RING ubiquitin ligase complex

KLHL25 KLHL13 ENC1

3.69e-0439753GO:0031463
GeneOntologyCellularComponentclathrin-sculpted glutamate transport vesicle membrane

SLC17A7 SLC17A8

4.50e-049752GO:0060203
GeneOntologyCellularComponentclathrin-sculpted glutamate transport vesicle

SLC17A7 SLC17A8

4.50e-049752GO:0060199
GeneOntologyCellularComponentdynein complex

DNAH12 DNAH7 DNAH1

9.65e-0454753GO:0030286
GeneOntologyCellularComponentchloride channel complex

SLC17A7 SLC17A8 CLCC1

1.13e-0357753GO:0034707
GeneOntologyCellularComponentclathrin-sculpted vesicle

SLC17A7 SLC17A8

1.48e-0316752GO:0060198
GeneOntologyCellularComponent9+2 motile cilium

SLC26A3 CATSPERE DNAH12 DNAH7 DNAH1

1.66e-03238755GO:0097729
GeneOntologyCellularComponentbrush border

SLC7A9 SLC26A3 SLC17A4 ITPR3

2.19e-03152754GO:0005903
DomainDynein_heavy_chain_D4_dom

DNAH12 DNAH7 DNAH1

2.02e-0514733IPR024317
DomainDynein_heavy_dom-2

DNAH12 DNAH7 DNAH1

2.02e-0514733IPR013602
DomainDHC_N2

DNAH12 DNAH7 DNAH1

2.02e-0514733PF08393
DomainAAA_8

DNAH12 DNAH7 DNAH1

2.02e-0514733PF12780
DomainDHC_fam

DNAH12 DNAH7 DNAH1

2.52e-0515733IPR026983
DomainDynein_heavy_dom

DNAH12 DNAH7 DNAH1

2.52e-0515733IPR004273
DomainDynein_heavy

DNAH12 DNAH7 DNAH1

2.52e-0515733PF03028
DomainRIH_assoc

RYR3 ITPR3

2.24e-046732PF08454
DomainRIH_assoc-dom

RYR3 ITPR3

2.24e-046732IPR013662
DomainRIH_dom

RYR3 ITPR3

2.24e-046732IPR000699
DomainIns145_P3_rcpt

RYR3 ITPR3

2.24e-046732IPR014821
DomainRyanodine_recept-rel

RYR3 ITPR3

2.24e-046732IPR015925
Domain-

RYR3 ITPR3

2.24e-0467321.25.10.30
DomainRYDR_ITPR

RYR3 ITPR3

2.24e-046732PF01365
DomainIns145_P3_rec

RYR3 ITPR3

2.24e-046732PF08709
DomainBTB-kelch_protein

KLHL25 KLHL13 ENC1

6.32e-0443733IPR017096
DomainMIR

RYR3 ITPR3

6.64e-0410732PS50919
DomainMIR

RYR3 ITPR3

6.64e-0410732PF02815
DomainMIR

RYR3 ITPR3

6.64e-0410732SM00472
DomainMIR_motif

RYR3 ITPR3

6.64e-0410732IPR016093
DomainMFS

SLC2A6 SLC17A4 SLC17A7 SLC17A8

8.47e-04108734PS50850
DomainDynein_HC_stalk

DNAH7 DNAH1

1.33e-0314732IPR024743
DomainMT

DNAH7 DNAH1

1.33e-0314732PF12777
DomainATPase_dyneun-rel_AAA

DNAH12 DNAH1

1.33e-0314732IPR011704
DomainAAA_5

DNAH12 DNAH1

1.33e-0314732PF07728
DomainKelch

KLHL25 KLHL13 ENC1

1.52e-0358733SM00612
DomainGal_Oxase/kelch_b-propeller

KLHL25 KLHL13 ENC1

1.59e-0359733IPR011043
DomainBACK

KLHL25 KLHL13 ENC1

1.67e-0360733SM00875
DomainBACK

KLHL25 KLHL13 ENC1

1.75e-0361733PF07707
DomainBACK

KLHL25 KLHL13 ENC1

1.75e-0361733IPR011705
DomainMFS_dom

SLC2A6 SLC17A4 SLC17A7 SLC17A8

1.88e-03134734IPR020846
DomainAa_trans

SLC38A4 SLC36A2

1.97e-0317732PF01490
DomainAA_transpt_TM

SLC38A4 SLC36A2

1.97e-0317732IPR013057
DomainKelch_1

KLHL25 KLHL13 ENC1

2.60e-0370733PF01344
DomainKelch_1

KLHL25 KLHL13 ENC1

2.60e-0370733IPR006652
DomainMFS_1

SLC17A4 SLC17A7 SLC17A8

3.41e-0377733PF07690
DomainMFS

SLC17A4 SLC17A7 SLC17A8

3.41e-0377733IPR011701
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC7A9 SLC26A3 SLC2A6 SLC38A4 SLC17A7 SLC17A8 SLC14A2 SLC36A2

1.71e-06238508MM15076
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC7A9 SLC26A3 SLC38A4 SLC17A7 SLC17A8 SLC36A2

2.12e-06108506M823
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC7A9 SLC26A3 SLC38A4 SLC17A7 SLC17A8 SLC36A2

2.24e-06109506MM15074
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC7A9 SLC26A3 SLC2A6 SLC38A4 SLC17A7 SLC17A8 SLC14A2 SLC36A2

2.39e-06249508M5988
PathwayREACTOME_SLC_TRANSPORTER_DISORDERS

SLC7A9 SLC26A3 SLC17A8 GCKR SLC36A2

2.55e-0599505M27474
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC7A9 SLC26A3 SLC2A6 SLC38A4 SLC17A7 SLC17A8 SLC14A2 ABCA8 SLC36A2 RYR3

1.15e-046815010MM14985
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH12 DNAH7 DNAH1

1.16e-0427503M47755
PathwayREACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE

SLC7A9 SLC38A4 SLC36A2

1.94e-0432503MM14957
PathwayREACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE

SLC7A9 SLC38A4 SLC36A2

2.13e-0433503M188
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC7A9 SLC26A3 SLC2A6 SLC38A4 SLC17A7 SLC17A8 SLC14A2 ABCA8 SLC36A2 RYR3

2.17e-047365010M27287
PathwayREACTOME_DISORDERS_OF_TRANSMEMBRANE_TRANSPORTERS

SLC7A9 SLC26A3 SLC17A8 GCKR SLC36A2

3.96e-04177505M27476
PathwayWP_AMINO_ACID_TRANSPORT_DEFECTS_IEMS

SLC7A9 SLC36A2

4.37e-049502M48047
PathwayKEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT

DNAH12 DNAH7 DNAH1

4.69e-0443503M47669
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH12 DNAH7 DNAH1

5.36e-0445503M47670
PathwayREACTOME_ORGANIC_ANION_TRANSPORTERS

SLC17A7 SLC17A8

7.95e-0412502M27350
PathwayREACTOME_ORGANIC_ANION_TRANSPORTERS

SLC17A7 SLC17A8

7.95e-0412502MM15087
PathwayWP_MFAP5MEDIATED_OVARIAN_CANCER_CELL_MOTILITY_AND_INVASIVENESS

RYR3 ITPR3

9.38e-0413502M39463
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH12 DNAH7 DNAH1

3.59e-06147639373155
Pubmed

Synaptic and extrasynaptic factors governing glutamatergic retinal waves.

SLC17A7 SLC17A8

4.71e-06276219409268
Pubmed

Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels.

SLC17A7 SLC17A8

1.41e-05376233440152
Pubmed

Lack of evidence for vesicular glutamate transporter expression in mouse astrocytes.

SLC17A7 SLC17A8

1.41e-05376223467360
Pubmed

Docking and homology modeling explain inhibition of the human vesicular glutamate transporters.

SLC17A7 SLC17A8

1.41e-05376217660252
Pubmed

Sociability and synapse subtype-specific defects in mice lacking SRPX2, a language-associated gene.

SRPX2 SLC17A7

1.41e-05376229920554
Pubmed

Characterization of the binding sites for the interactions between FKBP12 and intracellular calcium release channels.

RYR3 ITPR3

2.82e-05476222100703
Pubmed

IP3R-mediated Ca2+ signaling controls B cell proliferation through metabolic reprogramming.

CD19 ITPR3

2.82e-05476235494252
Pubmed

Loss of IP3 Receptor-Mediated Ca2+ Release in Mouse B Cells Results in Abnormal B Cell Development and Function.

CD19 ITPR3

2.82e-05476228615414
Pubmed

Amino acid transport across mammalian intestinal and renal epithelia.

SLC7A9 SLC38A4 SLC36A2

4.31e-053176318195088
Pubmed

Protocol to map multi-transmitter neurons in the mouse brain using intersectional strategy.

SLC17A7 SLC17A8

4.69e-05576236595933
Pubmed

Primary Ciliary Dyskinesia Associated Disease-Causing Variants in CCDC39 and CCDC40 Cause Axonemal Absence of Inner Dynein Arm Heavy Chains DNAH1, DNAH6, and DNAH7.

DNAH7 DNAH1

4.69e-05576239056782
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

RYR3 ITPR3

7.03e-05676223463619
Pubmed

IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.

RYR3 ITPR3

7.03e-05676216844763
Pubmed

A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.

RYR3 ITPR3

7.03e-05676220519450
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

RYR3 ITPR3

7.03e-05676225966694
Pubmed

B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1.

CD19 IL21R

7.03e-05676223045607
Pubmed

Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.

RYR3 ITPR3

9.83e-05776211860456
Pubmed

Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions.

CD19 IL21R

9.83e-05776223064231
Pubmed

Regulatory B cell (B10 Cell) expansion during Listeria infection governs innate and cellular immune responses in mice.

CD19 IL21R

9.83e-05776223275601
Pubmed

Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

DNAH12 DNAH1

9.83e-0577629256245
Pubmed

Update on the Kelch-like (KLHL) gene family.

KLHL25 KLHL13 ENC1

1.01e-044176323676014
Pubmed

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

RYR3 ITPR3

1.31e-04876219033399
Pubmed

Enteroendocrine cell types that drive food reward and aversion.

SLC17A7 SLC17A8

1.68e-04976235913117
Pubmed

IL-21 is a broad negative regulator of IgE class switch recombination in mouse and human B cells.

CD19 IL21R

2.10e-041076232130409
Pubmed

Evolutionary origin of amino acid transporter families SLC32, SLC36 and SLC38 and physiological, pathological and therapeutic aspects.

SLC38A4 SLC36A2

4.86e-041576223506890
Pubmed

Unpackaging the genetics of mammalian fertility: strategies to identify the "reproductive genome".

RNF212 DNAH1

5.54e-041676229878059
Pubmed

Intersectional mapping of multi-transmitter neurons and other cell types in the brain.

SLC17A7 SLC17A8

5.54e-041676235793636
Pubmed

H-2 haplotypes, genes, and antigens: second listing. I. Non-H-2 loci on chromosome 17.

C4BPA ITPR3

6.27e-04177626816725
Pubmed

The BMP antagonist gremlin 1 contributes to the development of cortical excitatory neurons, motor balance and fear responses.

SLC17A7 RYR3

6.27e-041776234184027
Pubmed

Engagement of the G3BP2-TRIM25 Interaction by Nucleocapsid Protein Suppresses the Type I Interferon Response in SARS-CoV-2-Infected Cells.

EVI5 DNAH12 PCNX3

6.29e-047676336560452
Pubmed

New gene functions in megakaryopoiesis and platelet formation.

GCKR SLFN14 GP1BA

7.57e-048176322139419
Pubmed

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

PRUNE2 DNAH12 TFB1M RTTN TCF25 DNAH1

7.68e-0449676631343991
Pubmed

Enhancer viruses for combinatorial cell-subclass-specific labeling.

SLC17A7 SLC17A8

8.73e-042076233789083
Pubmed

Pet-1 is required across different stages of life to regulate serotonergic function.

HTR1B SLC17A8

8.73e-042076220818386
Pubmed

WT1 maintains adrenal-gonadal primordium identity and marks a population of AGP-like progenitors within the adrenal gland.

TCF21 AKR1B10

8.73e-042076224135228
Pubmed

A ubiquitin-based effector-to-inhibitor switch coordinates early brain, craniofacial, and skin development.

KLHL25 KLHL13 ENC1

9.32e-048776337495603
Pubmed

Class 5 transmembrane semaphorins control selective Mammalian retinal lamination and function.

SLC17A7 SLC17A8

9.63e-042176221835343
Pubmed

Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.

SLC17A4 GCKR

9.63e-042176221943158
Pubmed

Sidekick 2 directs formation of a retinal circuit that detects differential motion.

SLC17A7 SLC17A8

1.16e-032376226287463
Pubmed

A novel missense variant in CUL3 shows altered binding ability to BTB-adaptor proteins leading to diverse phenotypes of CUL3-related disorders.

KLHL25 KLHL13

1.16e-032376233130828
Pubmed

Discovery and refinement of loci associated with lipid levels.

EVI5 PCNX3 GCKR ABCA8

1.20e-0321176424097068
Pubmed

Dimerization quality control ensures neuronal development and survival.

KLHL13 ENC1

1.26e-032476230190310
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PRUNE2 XPO6 IGSF1

1.56e-031047639205841
Pubmed

Excitatory neurons of the proprioceptive, interoceptive, and arousal hindbrain networks share a developmental requirement for Math1.

SLC17A7 SLC17A8

1.60e-032776220080794
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

SLC7A9 EVI5 ADGRG7 SLC26A3 SRPX2 KLHL13 BRAT1 DNAH7 CLCC1

2.01e-03129376915342556
Pubmed

Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.

SLC2A6 AKR1B10 GAA

2.03e-0311476328245920
Pubmed

Genome-wide association study of hematological and biochemical traits in a Japanese population.

GCKR SLC14A2 GP1BA

2.13e-0311676320139978
Cytoband2p23

GCKR HADHB

3.62e-04177622p23
GeneFamilySolute carriers

SLC7A9 SLC26A3 SLC2A6 SLC38A4 SLC17A4 SLC17A7 SLC17A8 SLC14A2 SLC36A2

5.58e-07395469752
GeneFamilyDyneins, axonemal

DNAH12 DNAH7 DNAH1

1.02e-0517463536
GeneFamilyKelch like|BTB domain containing

KLHL25 KLHL13 ENC1

1.65e-0442463617
GeneFamilyBasic leucine zipper proteins|BTB domain containing

KLHL25 KLHL13 ENC1

4.79e-03134463861
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

SRPX2 C4BPA

9.25e-03574621179
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

RNF212 CISD3 PITPNC1 BRAT1 DNAH7 ABCA8

4.68e-071707660f215911b5880eeffeb43230f7eeaf55b612eaf2
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_ALM_Slco2a1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KLHL25 CWH43 ENC1 SSTR1 RYR3

3.27e-061337659d7a08170d38ae9b2ff10a0fa505aeb3aae2824d
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1|E16.5-samps / Age Group, Lineage, Cell class and subclass

SRPX2 TCF21 IL21R SLC36A2 RYR3

8.81e-06163765f1ec2625b52664308968b01d8e0275e1e0751480
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Col23a1_Adamts2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CWH43 ENC1 SLC17A7 ZNF831 RYR3

1.02e-051687653fe432267656aff81b6d92c18d1b6fc0cde73d6a
ToppCellTCGA-Colorectal-Solid_Tissue_Normal-Colon_normal_tissue|TCGA-Colorectal / Sample_Type by Project: Shred V9

CWH43 SLC17A4 SLC17A7 SLC17A8 ABCA8

1.14e-0517276594842346c84542a5243bd765e49f4af8bc5182db
ToppCellTCGA-Colorectal-Solid_Tissue_Normal-Colon_normal_tissue-Colon_normal_tissue|TCGA-Colorectal / Sample_Type by Project: Shred V9

CWH43 SLC17A4 SLC17A7 SLC17A8 ABCA8

1.14e-051727655d654dd030ed22a701e15c5f09002951d99a52e8
ToppCell3'-Adult-Distal_Rectal-Epithelial-Tuft-related-Microfold_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADGRG7 SLC26A3 SULT1C2 SLC2A6 ULBP3

1.24e-051757658a37b2811f39bb9baa537e8755a29d559eb8185a
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

PRUNE2 TMEM130 SULT1C2 SLC17A4 DNAH7

1.35e-05178765544379f5a6145429762258d426b876bb36c112f5
ToppCellCOVID-19-kidney-tDL|COVID-19 / Disease (COVID-19 only), tissue and cell type

PRUNE2 SULT1C2 KLHL13 AKR1B10 SLC36A2

1.42e-05180765864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-secretory_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL25 DLGAP5 CENPI BRAT1 SLC14A2

1.46e-05181765b203b616584cdbd0bbb0e382b2916d0bd49d3526
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL25 DLGAP5 CENPI BRAT1 SLC14A2

1.46e-05181765c748c16fd20d1949d33ff6290dc9d9016c4dc86c
ToppCellTCGA-Colorectal-Solid_Tissue_Normal|TCGA-Colorectal / Sample_Type by Project: Shred V9

CWH43 SLC17A4 SLC17A7 SLC17A8 ABCA8

1.46e-0518176588f6f56f5f58b479d5db91b32c45934c045f88ea
Diseaseplatelet measurement

CCDC71L RTTN DLGAP5 MARK4 C4BPA GCKR SLFN14 SLC36A2

1.02e-06315728EFO_0005036
Diseaseplatelet component distribution width

PRUNE2 CCDC71L RTTN MARK4 C4BPA SLFN14 ZNF831 BRAT1 GAA GP1BA

1.45e-057557210EFO_0007984
Diseasemean platelet volume

CCDC71L SRPX2 PCNX3 RTTN DLGAP5 MARK4 C4BPA GCKR HADHB SLFN14 GP1BA

3.50e-0510207211EFO_0004584
Diseaseimmature platelet fraction

CCDC71L RTTN MARK4 SLFN14

1.78e-04114724EFO_0009187
Diseaseimmature platelet measurement

CCDC71L RTTN MARK4 SLFN14

2.09e-04119724EFO_0803541
Diseasealpha wave measurement, electroencephalogram measurement

TFB1M DNAH1

2.61e-0410722EFO_0004357, EFO_0006870
Diseaseatherosclerosis

CCDC71L SLC17A4

4.50e-0413722EFO_0003914
Diseaseuric acid measurement

SLC7A9 PCNX3 MARK4 SLC17A4 GCKR ARHGEF26 SLC14A2

7.19e-04610727EFO_0004761
DiseaseMHPG measurement, 5-HIAA measurement

KLHL13 SSTR1

7.80e-0417722EFO_0005132, EFO_0005133
Diseaseblood urea nitrogen measurement

TCF21 SLC38A4 GCKR PITPNC1 ARHGEF26 SLC14A2

8.32e-04452726EFO_0004741
Diseasee-selectin measurement

EVI5 SLC2A6

1.31e-0322722EFO_0004575
Diseaseamino acid measurement

HTR1B DNAH12 EXD1 MARK4 GCKR DNAH7 RYR3

1.33e-03678727EFO_0005134
Diseaseserum urea measurement

GCKR PITPNC1 ARHGEF26 SLC14A2

1.34e-03195724EFO_0009795
Diseaseurate measurement

SLC7A9 PCNX3 SLC17A4 COX7A2P2 GCKR ARHGEF26 SLC14A2 DNAH1

1.50e-03895728EFO_0004531
Diseaseglutamine measurement

SLC38A4 GCKR SLC36A2

1.74e-0397723EFO_0009768
DiseaseCalcium channel blocker use measurement

CCDC71L TCF21 AKR1B10 ZNF831

1.85e-03213724EFO_0009930
Diseaseplatelet-to-lymphocyte ratio

CCDC71L MARK4 SLFN14 ZNF831 ITPR3

1.95e-03363725EFO_0008446
Diseaseimmature platelet count

CCDC71L RTTN MARK4

2.24e-03106723EFO_0803544
Diseasecoronary artery disease

CCDC71L TCF21 PCNX3 MARK4 ZNF831 ARHGEF26 SLC14A2 ABCA8 DMXL1

2.43e-031194729EFO_0001645

Protein segments in the cluster

PeptideGeneStartEntry
PFSRLWKVSDPILFQ

C4BPA

21

P04003
FQATLRWLLSSPKTP

BRAT1

471

Q6PJG6
ALVWVFSISISLPPF

HTR1B

171

P28222
FKSWTRIRVPPDILS

CATSPERE

266

Q5SY80
VIPFRWVTSKPTFSS

AFDN-DT

231

Q9Y6Z5
WVTSKPTFSSCFLPR

AFDN-DT

236

Q9Y6Z5
VSKLWPTFFERPLVR

AKR1B10

76

O60218
EFKIKPFPLVSSSRW

ARHGEF26

641

Q96DR7
KSPLLWSFIVPVTII

ADGRG7

621

Q96K78
SWKALPSLVRPRVFI

CCDC154

591

A6NI56
LAFPLWESTKVVPLS

DMXL1

1181

Q9Y485
KGVTSIIPAITWFTF

COX7A2P2

81

O60397
LPTASKWALRFSIRP

HADHB

11

P55084
PVKFARLWTEIPTAI

ITPR3

796

Q14573
PWKPIRLPVFSSLSL

FAM171A1

101

Q5VUB5
FFTRPLLSKWCPKSL

KCNK18

171

Q7Z418
PSIPFSFTNETVWIK

MTO1

261

Q9Y2Z2
WFIRPVSPSLLKILA

EXD1

236

Q8NHP7
VKSALPSLTWFVPLL

ERVV-1

446

B6SEH8
PTVLWSLIRSKLFPE

PCNX3

1006

Q9H6A9
SSWFLTIFLTTFPLP

EVI5

321

O60447
SFRLWLTSYPSSKFP

DNAH12

2581

Q6ZR08
VLLSIPFFSVPVAWT

ORMDL1

36

Q9P0S3
SWLTAFVLTKSFLPV

SLC2A6

441

Q9UGQ3
SSLVPPTIRRKFWIN

PCDHA10

281

Q9Y5I2
KLFPSIISITWPLLF

GCKR

451

Q14397
SWKRPFTLVISFFSL

FAM189B

86

P81408
WLTSLPSNKFPVSIL

DNAH1

3761

Q9P2D7
VTDTFPKTWLLARPS

IGSF1

316

Q8N6C5
AIWKFPVPVLKTSRS

KLHL13

11

Q9P2N7
VPYSLIPTAFVSTWK

KLHL25

571

Q9H0H3
TWSRESPLKPFLKLS

CD19

51

P15391
LFSWASLIVIKPTSF

SLC7A9

111

P82251
SVFLVLAPIISKPTW

SLC7A9

421

P82251
WFPRTPARSVVALKT

CISD3

31

P0C7P0
ILPKPWRKSFLAASS

DNAH7

251

Q8WXX0
PRKRFAFSPSTWELT

FOXR1

116

Q6PIV2
FLTPSYTWTPLKTEV

DLGAP5

336

Q15398
PLFLEFPKDSSTWTV

GAA

726

P10253
SLPTFRSSLFLWVRP

GP1BA

601

P07359
TAPRLLRFPWSVKLT

MARK4

651

Q96L34
WRAATPTLTTFPTIR

CCDC71L

181

Q8N9Z2
IVFIPAFWSLKTHPL

IL21R

246

Q9HBE5
VPYSLIPTAFVSTWK

ENC1

571

O14682
VEIWSKPFASISFLP

CCDC168

3966

Q8NDH2
WIPFSSFSEVKPLLF

CENPI

461

Q92674
ITKPLTYNTLVTPWR

GPR21

131

Q99679
LFPSVILVSLPWVRS

SLC17A4

376

Q9Y2C5
SPIFLTITPFWKLVN

CWH43

51

Q9H720
LPSLSVFSLRWKLPS

RTP1

16

P59025
TVKCLKFSTFPWLPL

RTTN

166

Q86VV8
KFSTFPWLPLTTTDR

RTTN

171

Q86VV8
FPSLKLVIWSIPFSV

TAS2R41

181

P59536
VPFLVTSTLLRHWPF

SSTR1

111

P30872
LIFVKSWSPDVFSLP

SLFN14

106

P0C7P3
PSWFIRTILAVTRPF

PRUNE2

3001

Q8WUY3
FSWDLPIKVLPTSPT

RGP1

361

Q92546
IPFAISRVSTRWALP

SLC36A2

366

Q495M3
NLPFSVSTPLIIKWL

TFB1M

141

Q8WVM0
EPIPFWTFLSRILTG

NSDHL

271

Q15738
NPLTKFSTPWRRFFT

SLC17A7

286

Q9P2U7
KRIVLSLFPIASWLP

SLC26A3

51

P40879
TSVITLLFPKRPFSW

SLC38A4

436

Q969I6
RPPLFFLKSSFWSQT

ABCA8

431

O94911
IWLVPPTKALAVTFT

CLCC1

291

Q96S66
TASFCFIPWLTLSKP

RNF212

196

Q495C1
PKAIATTLSPWSFLI

ULBP3

221

Q9BZM4
LFLLFFLTPAVTPTW

SRPX2

11

O60687
WFSKRLPTFVNVPKD

RYR3

1236

Q15413
LKTHLSTQLLPPSFW

SULT1C2

106

O00338
SKLPSWARAVVPKIF

PITPNC1

66

Q9UKF7
SKAFSRLKTTLPWVP

TCF21

96

O43680
PWPSSYLTKTVLKVS

TMEM130

146

Q8N3G9
LAVTWSLTKLPFPLS

ZNF295-AS1

71

Q8N0V1
LFSWIPLSASITPSL

XPO6

256

Q96QU8
RSTWTPPDKSRPLFF

ZNF831

471

Q5JPB2
VSRLRPFFWLSPLAS

TRIM4

476

Q9C037
SIFSKWDLPVFTLPF

SLC14A2

226

Q15849
SKWDLPVFTLPFNIT

SLC14A2

691

Q15849
RVYPKCTWLTTPKST

TCF25

211

Q9BQ70
SKFSTPWKRFFTSLP

SLC17A8

301

Q8NDX2