Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	3',5'-cyclic-AMP phosphodiesterase activity	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	4.05e-10	22	87	6	GO:0004115
GeneOntologyMolecularFunction	3',5'-cyclic-GMP phosphodiesterase activity	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	7.26e-10	24	87	6	GO:0047555
GeneOntologyMolecularFunction	3',5'-cyclic-nucleotide phosphodiesterase activity	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	9.51e-10	25	87	6	GO:0004114
GeneOntologyMolecularFunction	cyclic-nucleotide phosphodiesterase activity	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	1.58e-09	27	87	6	GO:0004112
GeneOntologyMolecularFunction	cAMP binding	PDE1C PDE4A PDE4B PDE4D	3.97e-06	25	87	4	GO:0030552
GeneOntologyMolecularFunction	phosphoric diester hydrolase activity	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	4.13e-06	97	87	6	GO:0008081
GeneOntologyMolecularFunction	3',5'-cGMP-inhibited cyclic-nucleotide phosphodiesterase activity	PDE3A PDE3B	1.88e-05	2	87	2	GO:0004119
GeneOntologyMolecularFunction	cyclic nucleotide binding	PDE1C PDE4A PDE4B PDE4D	2.46e-05	39	87	4	GO:0030551
GeneOntologyMolecularFunction	fructose-bisphosphate aldolase activity	ALDOA ALDOC	5.61e-05	3	87	2	GO:0004332
GeneOntologyMolecularFunction	hydrolase activity, acting on ester bonds	PDE1C PDE3A PDE3B PDE4A PTPN11 PDE4B PDE4D HELZ2 XRN1 ACOT2 TSEN2 HARBI1	1.92e-04	807	87	12	GO:0016788
GeneOntologyMolecularFunction	tubulin binding	PDE4B MAST1 GOLGA8B RABGAP1 ALDOA MAST2 GOLGA8A NLRP5	5.56e-04	428	87	8	GO:0015631
GeneOntologyMolecularFunction	aldehyde-lyase activity	ALDOA ALDOC	1.01e-03	11	87	2	GO:0016832
GeneOntologyMolecularFunction	GTPase activator activity	DOCK1 TBC1D4 SRGAP3 SRGAP1 RABGAP1 SIPA1	1.38e-03	279	87	6	GO:0005096
GeneOntologyMolecularFunction	phosphoric ester hydrolase activity	PDE1C PDE3A PDE3B PDE4A PTPN11 PDE4B PDE4D	1.48e-03	386	87	7	GO:0042578
GeneOntologyBiologicalProcess	regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	PDE3A PDE3B PDE4A PDE4B PDE4D	6.88e-08	26	86	5	GO:0106070
GeneOntologyBiologicalProcess	cAMP-mediated signaling	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	7.62e-07	76	86	6	GO:0019933
GeneOntologyBiologicalProcess	negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	PDE3A PDE3B PDE4B PDE4D	8.24e-07	18	86	4	GO:0106072
GeneOntologyBiologicalProcess	cAMP catabolic process	PDE4A PDE4B PDE4D	5.77e-06	9	86	3	GO:0006198
GeneOntologyBiologicalProcess	negative regulation of relaxation of cardiac muscle	PDE4B PDE4D	1.72e-05	2	86	2	GO:1901898
GeneOntologyBiologicalProcess	cyclic nucleotide catabolic process	PDE4A PDE4B PDE4D	2.46e-05	14	86	3	GO:0009214
GeneOntologyBiologicalProcess	purine ribonucleotide catabolic process	PDE4A PDE4B PDE4D ACOT2 ALDOA ALDOC	7.57e-05	169	86	6	GO:0009154
GeneOntologyBiologicalProcess	ribonucleotide catabolic process	PDE4A PDE4B PDE4D ACOT2 ALDOA ALDOC	1.01e-04	178	86	6	GO:0009261
GeneOntologyBiologicalProcess	purine nucleotide catabolic process	PDE4A PDE4B PDE4D ACOT2 ALDOA ALDOC	1.14e-04	182	86	6	GO:0006195
GeneOntologyBiologicalProcess	purine-containing compound catabolic process	PDE4A PDE4B PDE4D ACOT2 ALDOA ALDOC	1.36e-04	188	86	6	GO:0072523
GeneOntologyBiologicalProcess	cAMP metabolic process	PDE4A PDE4B PDE4D	1.51e-04	25	86	3	GO:0046058
GeneOntologyBiologicalProcess	nucleotide catabolic process	PDE4A PDE4B PDE4D ACOT2 ALDOA ALDOC	2.35e-04	208	86	6	GO:0009166
GeneOntologyBiologicalProcess	nucleoside phosphate catabolic process	PDE4A PDE4B PDE4D ACOT2 ALDOA ALDOC	2.88e-04	216	86	6	GO:1901292
GeneOntologyBiologicalProcess	negative regulation of relaxation of muscle	PDE4B PDE4D	3.56e-04	7	86	2	GO:1901078
GeneOntologyBiologicalProcess	negative regulation of G protein-coupled receptor signaling pathway	PDE3A PDE3B PDE4B PDE4D	3.67e-04	81	86	4	GO:0045744
GeneOntologyBiologicalProcess	carbohydrate derivative catabolic process	PDE4A PDE4B CHIA PDE4D ACOT2 ALDOA ALDOC	4.04e-04	323	86	7	GO:1901136
GeneOntologyBiologicalProcess	gastrulation with mouth forming second	MEGF8 UGDH ACVR1	4.16e-04	35	86	3	GO:0001702
GeneOntologyBiologicalProcess	determination of left/right symmetry	IFT140 MEGF8 ACVR1 RNF207 DNAH11	4.65e-04	154	86	5	GO:0007368
GeneOntologyBiologicalProcess	left/right pattern formation	IFT140 MEGF8 ACVR1 RNF207 DNAH11	5.86e-04	162	86	5	GO:0060972
GeneOntologyBiologicalProcess	fructose 1,6-bisphosphate metabolic process	ALDOA ALDOC	6.07e-04	9	86	2	GO:0030388
GeneOntologyBiologicalProcess	regulation of relaxation of cardiac muscle	PDE4B PDE4D	6.07e-04	9	86	2	GO:1901897
GeneOntologyBiologicalProcess	regulation of cAMP-mediated signaling	PDE3A PDE3B PDE4D	6.18e-04	40	86	3	GO:0043949
GeneOntologyBiologicalProcess	determination of bilateral symmetry	IFT140 MEGF8 ACVR1 RNF207 DNAH11	6.37e-04	165	86	5	GO:0009855
GeneOntologyBiologicalProcess	specification of symmetry	IFT140 MEGF8 ACVR1 RNF207 DNAH11	6.37e-04	165	86	5	GO:0009799
HumanPheno	Short metacarpal	PDE3A PDE4D MEGF8 VPS35L ACVR1 PRMT7	3.56e-05	129	26	6	HP:0010049
HumanPheno	Aplasia/Hypoplasia involving the metacarpal bones	PDE3A PDE4D MEGF8 VPS35L ACVR1 PRMT7	6.13e-05	142	26	6	HP:0005914
HumanPheno	Abnormality of the metacarpal bones	IFT140 PDE3A PDE4D MEGF8 VPS35L ACVR1 PRMT7	1.04e-04	228	26	7	HP:0001163
HumanPheno	Abnormal metacarpal morphology	IFT140 PDE3A PDE4D MEGF8 VPS35L ACVR1 PRMT7	1.04e-04	228	26	7	HP:0005916
HumanPheno	Abnormal metatarsal morphology	IFT140 PDE4D VPS35L ACVR1 PRMT7 POMK	1.15e-04	159	26	6	HP:0001832
MousePheno	atrioventricular septal defect	DOCK1 IFT140 PTPN11 MEGF8 TRAPPC10 DNAH11	3.19e-06	84	68	6	MP:0010412
MousePheno	abnormal atrioventricular septum morphology	DOCK1 IFT140 PTPN11 MEGF8 TRAPPC10 DNAH11	3.92e-06	87	68	6	MP:0010592
MousePheno	abnormal atrioventricular valve morphology	DOCK1 IFT140 PTPN11 MEGF8 DNAH11	2.07e-05	69	68	5	MP:0002745
MousePheno	abnormal heart atrium and ventricle connection	DOCK1 IFT140 PTPN11 MEGF8 DNAH11	3.11e-05	75	68	5	MP:0010435
MousePheno	abnormal mitral valve morphology	DOCK1 PTPN11 MEGF8 DNAH11	4.53e-05	41	68	4	MP:0000286
MousePheno	abnormal heart valve morphology	DOCK1 IFT140 PTPN11 MEGF8 PRMT7 DNAH11	1.38e-04	163	68	6	MP:0000285
Domain	PDEase_I	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	4.10e-10	21	86	6	PF00233
Domain	PDEASE_I	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	4.10e-10	21	86	6	PS00126
Domain	PDEase_CS	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	4.10e-10	21	86	6	IPR023174
Domain	-	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	5.61e-10	22	86	6	1.10.1300.10
Domain	PDEase_catalytic_dom	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	7.57e-10	23	86	6	IPR002073
Domain	HDc	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	1.01e-09	24	86	6	SM00471
Domain	HD/PDEase_dom	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	1.01e-09	24	86	6	IPR003607
Domain	PDEase	PDE1C PDE4A PDE4B PDE4D	1.54e-06	19	86	4	IPR023088
Domain	FBA_I	ALDOA ALDOC	6.27e-05	3	86	2	IPR000741
Domain	Glycolytic	ALDOA ALDOC	6.27e-05	3	86	2	PF00274
Domain	Aldolase_I_AS	ALDOA ALDOC	6.27e-05	3	86	2	IPR029768
Domain	ALDOLASE_CLASS_I	ALDOA ALDOC	6.27e-05	3	86	2	PS00158
Domain	DUF1908	MAST1 MAST2	1.25e-04	4	86	2	PF08926
Domain	MA_Ser/Thr_Kinase_dom	MAST1 MAST2	1.25e-04	4	86	2	IPR015022
Domain	MAST_pre-PK_dom	MAST1 MAST2	1.25e-04	4	86	2	IPR023142
Domain	-	MAST1 MAST2	1.25e-04	4	86	2	1.20.1480.20
Domain	PDZ	WHRN MAST1 SIPA1 MAST2 PDZRN4	4.87e-04	141	86	5	PF00595
Domain	PDZ	WHRN MAST1 SIPA1 MAST2 PDZRN4	6.07e-04	148	86	5	SM00228
Domain	-	WHRN MAST1 SIPA1 MAST2 PDZRN4	6.45e-04	150	86	5	2.30.42.10
Domain	PDZ	WHRN MAST1 SIPA1 MAST2 PDZRN4	6.65e-04	151	86	5	PS50106
Domain	PDZ	WHRN MAST1 SIPA1 MAST2 PDZRN4	6.85e-04	152	86	5	IPR001478
Domain	CUB	OVCH2 MEGF8 CDCP1	1.87e-03	53	86	3	PS01180
Domain	CUB_dom	OVCH2 MEGF8 CDCP1	2.31e-03	57	86	3	IPR000859
Domain	Cyclin_C	CCNJL CCNJ	2.72e-03	17	86	2	PF02984
Domain	Cyclin_C-dom	CCNJL CCNJ	2.72e-03	17	86	2	IPR004367
Domain	Cyclin_C	CCNJL CCNJ	2.72e-03	17	86	2	SM01332
Domain	GOLGA2L5	GOLGA8B GOLGA8A	3.06e-03	18	86	2	PF15070
Domain	Golgin_A	GOLGA8B GOLGA8A	3.06e-03	18	86	2	IPR024858
Domain	FCH	SRGAP3 SRGAP1	4.56e-03	22	86	2	PF00611
Domain	FCH	SRGAP3 SRGAP1	4.56e-03	22	86	2	SM00055
Domain	FCH_dom	SRGAP3 SRGAP1	4.98e-03	23	86	2	IPR001060
Domain	F_BAR	SRGAP3 SRGAP1	5.87e-03	25	86	2	IPR031160
Domain	F_BAR	SRGAP3 SRGAP1	5.87e-03	25	86	2	PS51741
Domain	MetalloPept_cat_dom	PAPPA2 ADAM9 ADAMTS16	6.21e-03	81	86	3	IPR024079
Domain	-	PAPPA2 ADAM9 ADAMTS16	6.21e-03	81	86	3	3.40.390.10
Pathway	WP_PHOSPHODIESTERASES_IN_NEURONAL_FUNCTION	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	1.25e-07	55	61	6	M39763
Pathway	REACTOME_DARPP_32_EVENTS	PDE4A PDE4B PDE4D	4.15e-05	16	61	3	MM14699
Pathway	KEGG_PURINE_METABOLISM	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	6.23e-05	159	61	6	M14314
Pathway	WP_PURINE_METABOLISM	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	9.33e-05	171	61	6	MM15909
Pathway	WP_SILDENAFIL_TREATMENT	PDE4A PDE4B PDE4D	1.28e-04	23	61	3	M46455
Pathway	REACTOME_DARPP_32_EVENTS	PDE4A PDE4B PDE4D	1.46e-04	24	61	3	M751
Pathway	REACTOME_OPIOID_SIGNALLING	PDE1C PDE4A PDE4B PDE4D	2.48e-04	71	61	4	MM14491
Pubmed	Inhibition of type 5 phosphodiesterase counteracts β2-adrenergic signalling in beating cardiomyocytes.	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	6.07e-13	14	87	6	25852085
Pubmed	Overview of PDEs and their regulation.	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	3.50e-11	25	87	6	17307970
Pubmed	Inhibition of PDE3B augments PDE4 inhibitor-induced apoptosis in a subset of patients with chronic lymphocytic leukemia.	PDE3B PDE4A PDE4B PDE4D	3.65e-11	4	87	4	11839681
Pubmed	HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway.	PDE1C PDE3A PDE3B PDE4A PDE4D	6.74e-09	27	87	5	11156964
Pubmed	Nonredundant function of phosphodiesterases 4D and 4B in neutrophil recruitment to the site of inflammation.	PDE4A PDE4B PDE4D	1.51e-08	3	87	3	15585880
Pubmed	Cyclic AMP phosphodiesterases are localized in regions of the mouse brain associated with reinforcement, movement, and affect.	PDE4A PDE4B PDE4D	1.51e-08	3	87	3	10213096
Pubmed	The upstream conserved regions (UCRs) mediate homo- and hetero-oligomerization of type 4 cyclic nucleotide phosphodiesterases (PDE4s).	PDE4A PDE4B PDE4D	1.51e-08	3	87	3	24555506
Pubmed	Critical role of PDE4D in beta2-adrenoceptor-dependent cAMP signaling in mouse embryonic fibroblasts.	PDE4A PDE4B PDE4D	1.51e-08	3	87	3	18508768
Pubmed	Differential expression and function of phosphodiesterase 4 (PDE4) subtypes in human primary CD4+ T cells: predominant role of PDE4D.	PDE4A PDE4B PDE4D	1.51e-08	3	87	3	17404263
Pubmed	Specific role of phosphodiesterase 4B in lipopolysaccharide-induced signaling in mouse macrophages.	PDE4A PDE4B PDE4D	1.51e-08	3	87	3	16034090
Pubmed	Impact of phosphodiesterases PDE3 and PDE4 on 5-hydroxytryptamine receptor4-mediated increase of cAMP in human atrial fibrillation.	PDE3A PDE3B PDE4A	1.51e-08	3	87	3	32949251
Pubmed	Molecular cloning and transient expression in COS7 cells of a novel human PDE4B cAMP-specific phosphodiesterase, HSPDE4B3.	PDE4A PDE4B PDE4D	6.04e-08	4	87	3	9371714
Pubmed	Ibudilast (AV411), and its AV1013 analog, reduce HIV-1 replication and neuronal death induced by HIV-1 and morphine.	PDE4A PDE4B PDE4D	6.04e-08	4	87	3	24732776
Pubmed	Phosphoinositide 3-kinase γ protects against catecholamine-induced ventricular arrhythmia through protein kinase A-mediated regulation of distinct phosphodiesterases.	PDE3A PDE4A PDE4B	6.04e-08	4	87	3	23008439
Pubmed	Assessment of PDE4 Inhibitor-Induced Hypothermia as a Correlate of Nausea in Mice.	PDE4A PDE4B PDE4D	6.04e-08	4	87	3	34943270
Pubmed	Phosphodiesterase 4B in the cardiac L-type Ca²⁺ channel complex regulates Ca²⁺ current and protects against ventricular arrhythmias in mice.	PDE4A PDE4B PDE4D	6.04e-08	4	87	3	21670503
Pubmed	PAN-selective inhibition of cAMP-phosphodiesterase 4 (PDE4) induces gastroparesis in mice.	PDE4A PDE4B PDE4D	6.04e-08	4	87	3	32738081
Pubmed	A family of human phosphodiesterases homologous to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs.	PDE4A PDE4B PDE4D	6.04e-08	4	87	3	8413254
Pubmed	Phosphodiesterase 4D is required for beta2 adrenoceptor subtype-specific signaling in cardiac myocytes.	PDE4A PDE4B PDE4D	6.04e-08	4	87	3	15644445
Pubmed	Role of phosphodiesterases in the shaping of sub-plasma-membrane cAMP oscillations and pulsatile insulin secretion.	PDE4A PDE4B PDE4D	6.04e-08	4	87	3	22946044
Pubmed	Inhibition of cAMP-phosphodiesterase 4 (PDE4) potentiates the anesthetic effects of Isoflurane in mice.	PDE4A PDE4B PDE4D	6.04e-08	4	87	3	33609559
Pubmed	The cAMP-phosphodiesterase 4 (PDE4) controls β-adrenoceptor- and CFTR-dependent saliva secretion in mice.	PDE4A PDE4B PDE4D	1.51e-07	5	87	3	33944911
Pubmed	Interaction between LIS1 and PDE4, and its role in cytoplasmic dynein function.	PDE4A PDE4B PDE4D	1.51e-07	5	87	3	21652625
Pubmed	A mouse homolog of dunce, a gene important for learning and memory in Drosophila, is preferentially expressed in olfactory receptor neurons.	PDE4A PDE4B PDE4D	1.51e-07	5	87	3	8586960
Pubmed	Phosphodiesterase 4B negatively regulates endotoxin-activated interleukin-1 receptor antagonist responses in macrophages.	PDE4A PDE4B PDE4D	1.51e-07	5	87	3	28383060
Pubmed	Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum.	PDE4A PDE4B PDE4D	3.01e-07	6	87	3	18923023
Pubmed	Rewiring of RSK-PDZ Interactome by Linear Motif Phosphorylation.	WHRN MAST1 MAST2 PDZRN4	1.60e-06	34	87	4	30726710
Pubmed	Chromosome localizations of genes for five cAMP-specific phosphodiesterases in man and mouse.	PDE4A PDE4B PDE4D	4.25e-06	13	87	3	8009369
Pubmed	Isolation and characterization of cDNAs corresponding to two human calcium, calmodulin-regulated, 3',5'-cyclic nucleotide phosphodiesterases.	PDE1C PDE3A PDE3B	4.25e-06	13	87	3	8557689
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	DOCK1 IFT140 MEGF8 TRAPPC10 DNAH11	5.45e-06	100	87	5	25807483
Pubmed	Phosphodiesterase type 3A (PDE3A), but not type 3B (PDE3B), contributes to the adverse cardiac remodeling induced by pressure overload.	PDE3A PDE3B	6.19e-06	2	87	2	31051182
Pubmed	Phosphodiesterase 4B is essential for T(H)2-cell function and development of airway hyperresponsiveness in allergic asthma.	PDE4A PDE4B	6.19e-06	2	87	2	21047676
Pubmed	Effects of PDE4 gene polymorphisms on efficacy and adverse drug events of ritodrine therapy in preterm labor patients: a prospective observational study.	PDE4B PDE4D	6.19e-06	2	87	2	31324945
Pubmed	Overexpression of phosphodiesterase-4 subtypes involved in surgery-induced neuroinflammation and cognitive dysfunction in mice.	PDE4B PDE4D	6.19e-06	2	87	2	28235598
Pubmed	Pde3a and Pde3b regulation of murine pulmonary artery smooth muscle cell growth and metabolism.	PDE3A PDE3B	6.19e-06	2	87	2	39435735
Pubmed	Structure and expression of mouse aldolase genes. Brain-specific aldolase C amino acid sequence is closely related to aldolase A.	ALDOA ALDOC	6.19e-06	2	87	2	3009179
Pubmed	ADAM9 enhances CDCP1 protein expression by suppressing miR-218 for lung tumor metastasis.	ADAM9 CDCP1	6.19e-06	2	87	2	26553452
Pubmed	Phosphodiesterase 1C is dispensable for rapid response termination of olfactory sensory neurons.	PDE1C PDE4A	6.19e-06	2	87	2	19305400
Pubmed	A pathophysiological role of PDE3 in allergic airway inflammation.	PDE3A PDE3B	6.19e-06	2	87	2	29367458
Pubmed	Crystal structures of the catalytic domain of phosphodiesterase 4B complexed with AMP, 8-Br-AMP, and rolipram.	PDE4B PDE4D	6.19e-06	2	87	2	15003452
Pubmed	Slit-Robo GTPase-activating proteins are differentially expressed in murine dorsal root ganglia: modulation by peripheral nerve injury.	SRGAP3 SRGAP1	6.19e-06	2	87	2	22271578
Pubmed	PDE4D plays a critical role in the control of airway smooth muscle contraction.	PDE4B PDE4D	6.19e-06	2	87	2	14519662
Pubmed	Phosphodiesterase 3A (PDE3A) deletion suppresses proliferation of cultured murine vascular smooth muscle cells (VSMCs) via inhibition of mitogen-activated protein kinase (MAPK) signaling and alterations in critical cell cycle regulatory proteins.	PDE3A PDE3B	6.19e-06	2	87	2	21632535
Pubmed	Anxiogenic-like behavioral phenotype of mice deficient in phosphodiesterase 4B (PDE4B).	PDE4B PDE4D	6.19e-06	2	87	2	17700644
Pubmed	PGE(1) stimulation of HEK293 cells generates multiple contiguous domains with different [cAMP]: role of compartmentalized phosphodiesterases.	PDE4B PDE4D	6.19e-06	2	87	2	17088426
Pubmed	PDE4D and PDE4B function in distinct subcellular compartments in mouse embryonic fibroblasts.	PDE4B PDE4D	6.19e-06	2	87	2	21288894
Pubmed	Diazepam and rolipram differentially inhibit cyclic AMP-specific phosphodiesterases PDE4A1 and PDE4B3 in the mouse.	PDE4A PDE4B	6.19e-06	2	87	2	11267656
Pubmed	Human autoantibodies to a novel Golgi protein golgin-67: high similarity with golgin-95/gm 130 autoantigen.	GOLGA8B GOLGA8A	6.19e-06	2	87	2	10677249
Pubmed	Role of phosphodiesterase type 3A and 3B in regulating platelet and cardiac function using subtype-selective knockout mice.	PDE3A PDE3B	6.19e-06	2	87	2	17482796
Pubmed	Stimulation of p70S6 kinase via a growth hormone-controlled phosphatidylinositol 3-kinase pathway leads to the activation of a PDE4A cyclic AMP-specific phosphodiesterase in 3T3-F442A preadipocytes.	PDE4A PDE4D	6.19e-06	2	87	2	9520403
Pubmed	Targeted disruption of PDE3B, but not PDE3A, protects murine heart from ischemia/reperfusion injury.	PDE3A PDE3B	6.19e-06	2	87	2	25877153
Pubmed	Atropine augments cardiac contractility by inhibiting cAMP-specific phosphodiesterase type 4.	PDE4B PDE4D	6.19e-06	2	87	2	29123207
Pubmed	Identification and characterization of a novel Golgi protein, golgin-67.	GOLGA8B GOLGA8A	6.19e-06	2	87	2	10660574
Pubmed	Demonstration of the expression and the enzymatic activity of N-acetylglucosaminyltransferase IX in the mouse brain.	MGAT5 GOLGA8B GOLGA8A	6.73e-06	15	87	3	16413118
Pubmed	Alteration of Neuronal Excitability and Short-Term Synaptic Plasticity in the Prefrontal Cortex of a Mouse Model of Mental Illness.	PDE4A PDE4B PDE4D	8.27e-06	16	87	3	28283561
Pubmed	Intraflagellar transport molecules in ciliary and nonciliary cells of the retina.	IFT140 GOLGA8B GOLGA8A	1.67e-05	20	87	3	20368623
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	NAA25 MTA3 CEP85L HECTD2 ADAM9 PSMA3 VPS35L OSBPL1A ZNF521 MAST1 SNRNP70 ALDOA LRP1B	1.82e-05	1285	87	13	35914814
Pubmed	Mode of interactions of human aldolase isozymes with cytoskeletons.	ALDOA ALDOC	1.85e-05	3	87	2	9244396
Pubmed	Ablation of calcineurin Aβ reveals hyperlipidemia and signaling cross-talks with phosphodiesterases.	PDE3B PDE4D	1.85e-05	3	87	2	23258544
Pubmed	Aldolase positively regulates of the canonical Wnt signaling pathway.	ALDOA ALDOC	1.85e-05	3	87	2	24993527
Pubmed	Iloprost- and isoproterenol-induced increases in cAMP are regulated by different phosphodiesterases in erythrocytes of both rabbits and humans.	PDE3A PDE4D	1.85e-05	3	87	2	19252089
Pubmed	HELZ2: a new, interferon-regulated, human 3'-5' exoribonuclease of the RNB family is expressed from a non-canonical initiation codon.	LOXL1 HELZ2	1.85e-05	3	87	2	37602378
Pubmed	Leukocyte phosphodiesterase expression after lipopolysaccharide and during sepsis and its relationship with HLA-DR expression.	PDE4A PDE4B	1.85e-05	3	87	2	28356347
Pubmed	Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer.	MAST1 MAST2	1.85e-05	3	87	2	22101766
Pubmed	ADAM9 enhances CDCP1 by inhibiting miR-1 through EGFR signaling activation in lung cancer metastasis.	ADAM9 CDCP1	1.85e-05	3	87	2	28537886
Pubmed	Molecular cloning and chromosomal assignment of the human homologue of the rat cGMP-inhibited phosphodiesterase 1 (PDE3A)--a gene involved in fat metabolism located at 11p 15.1.	PDE3A PDE3B	1.85e-05	3	87	2	8921398
Pubmed	Numerous distinct PKA-, or EPAC-based, signalling complexes allow selective phosphodiesterase 3 and phosphodiesterase 4 coordination of cell adhesion.	PDE3B PDE4D	1.85e-05	3	87	2	17884339
Pubmed	BDNF and PDE4, but not the GRPR, regulate viability of human medulloblastoma cells.	PDE4A GRPR	1.85e-05	3	87	2	19642024
Pubmed	Differential regulation of endothelial cell permeability by cGMP via phosphodiesterases 2 and 3.	PDE3A PDE4A	1.85e-05	3	87	2	17704206
Pubmed	Genetic Ablation of Type III Adenylyl Cyclase Exerts Region-Specific Effects on Cilia Architecture in the Mouse Nose.	PDE1C PDE4A	1.85e-05	3	87	2	26942602
Pubmed	The emerging role of the MiR-1272-ADAM9-CDCP1 signaling pathway in the progression of glioma.	ADAM9 CDCP1	1.85e-05	3	87	2	33260155
Pubmed	Dynamic expression of the Slit-Robo GTPase activating protein genes during development of the murine nervous system.	SRGAP3 SRGAP1	1.85e-05	3	87	2	19137586
Pubmed	Human skeletal-muscle aldolase: N-terminal sequence analysis of CNBr- and o-iodosobenzoic acid-cleavage fragments.	ALDOA ALDOC	1.85e-05	3	87	2	6696436
Pubmed	Pivotal role of cyclic nucleoside phosphodiesterase 4 in Tat-mediated CD4+ T cell hyperactivation and HIV type 1 replication.	PDE4A PDE4B	1.85e-05	3	87	2	11114167
Pubmed	Phospholipase D2 directly interacts with aldolase via Its PH domain.	ALDOA ALDOC	1.85e-05	3	87	2	11876650
Pubmed	A polymerase chain reaction strategy to identify and clone cyclic nucleotide phosphodiesterase cDNAs. Molecular cloning of the cDNA encoding the 63-kDa calmodulin-dependent phosphodiesterase.	PDE1C PDE4D	1.85e-05	3	87	2	1326532
Pubmed	Dorsal root ganglion axon bifurcation tolerates increased cyclic GMP levels: the role of phosphodiesterase 2A and scavenger receptor Npr3.	PDE1C PDE3A PDE3B	1.95e-05	21	87	3	27740716
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	WHRN IFT140 TBC1D4 MAST2 TSEN2	1.95e-05	130	87	5	12421765
Pubmed	Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data.	PDE3A CEP85L LOXL1	2.95e-05	24	87	3	19584346
Pubmed	ALDOA coordinates PDE3A through the β-catenin/ID3 axis to stimulate cancer metastasis and M2 polarization in lung cancer with EGFR mutations.	PDE3A ALDOA	3.70e-05	4	87	2	38244313
Pubmed	Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases.	MAST1 MAST2	3.70e-05	4	87	2	15951562
Pubmed	mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module.	PDE4A PDE4D	3.70e-05	4	87	2	11296225
Pubmed	Interactions between beta 2-syntrophin and a family of microtubule-associated serine/threonine kinases.	MAST1 MAST2	3.70e-05	4	87	2	10404183
Pubmed	Interaction between aldolase and vacuolar H+-ATPase: evidence for direct coupling of glycolysis to the ATP-hydrolyzing proton pump.	ALDOA ALDOC	3.70e-05	4	87	2	11399750
Pubmed	Mouse oocytes develop in cysts with the help of nurse cells.	GOLGA8B GOLGA8A NLRP5	3.77e-05	26	87	3	35623357
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	MGAT5 TBC1D4 MEGF8 DNAJC16 LOXL1 TM9SF4 ADAM9 TTI1 RABGAP1 POMK LRP1B CREB3L2	4.44e-05	1201	87	12	35696571
Pubmed	The Y172 Monoclonal Antibody Against p-c-Jun (Ser63) Is a Marker of the Postsynaptic Compartment of C-Type Cholinergic Afferent Synapses on Motoneurons.	TMBIM4 GOLGA8B GOLGA8A	4.73e-05	28	87	3	32038174
Pubmed	Decreased Activity of the Ghrhr and Gh Promoters Causes Dominantly Inherited GH Deficiency in Humanized GH1 Mouse Models.	GOLGA8B GOLGA8A CREB3L2	5.27e-05	29	87	3	31436800
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	PDE1C VPS18 PDE4D NCKAP1 SRGAP3 XRN1 TRAPPC10 MAST1 DGKZ SIPA1 ALDOA ALDOC DNAH11	5.52e-05	1431	87	13	37142655
Pubmed	Selective SUMO modification of cAMP-specific phosphodiesterase-4D5 (PDE4D5) regulates the functional consequences of phosphorylation by PKA and ERK.	PDE4A PDE4D	6.16e-05	5	87	2	20196770
Pubmed	Evolutionary implications of the human aldolase-A, -B, -C, and -pseudogene chromosome locations.	ALDOA ALDOC	6.16e-05	5	87	2	3674018
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	PDE3A PTPN11 PDE4D TBC1D4 MTA3 NCKAP1 PSMA3 UGDH TTI1 RABGAP1 ALDOA ALDOC TSEN2	6.53e-05	1455	87	13	22863883
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	WHRN MEGF8 NCKAP1 SRGAP3 DNAJC16 ADAM9 MAST1	7.46e-05	407	87	7	12693553
Pubmed	SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance.	SRGAP3 SRGAP1	9.22e-05	6	87	2	33514561
Pubmed	FNBP2 gene on human chromosome 1q32.1 encodes ARHGAP family protein with FCH, FBH, RhoGAP and SH3 domains.	SRGAP3 SRGAP1	9.22e-05	6	87	2	12736724
Pubmed	Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway.	SRGAP3 SRGAP1	9.22e-05	6	87	2	11672528
Pubmed	Quantifying domain-ligand affinities and specificities by high-throughput holdup assay.	MAST1 MAST2 PDZRN4	1.02e-04	36	87	3	26053890
Pubmed	DISC1, PDE4B, and NDE1 at the centrosome and synapse.	PDE4B PDE4D	1.29e-04	7	87	2	18983980
Pubmed	Evidence for a role of srGAP3 in the positioning of commissural axons within the ventrolateral funiculus of the mouse spinal cord.	SRGAP3 SRGAP1	1.29e-04	7	87	2	21655271
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	PDE4A PDE4B NCKAP1 SRGAP3 ADAM9 PAK5 GOLGA8B DGKZ SIPA1 GOLGA8A	1.47e-04	963	87	10	28671696
Interaction	PIK3CG interactions	PDE3B PTPN11 PDE4D ACVR1 PRMT7	5.56e-06	59	87	5	int:PIK3CG
Cytoband	Ensembl 112 genes in cytogenetic band chr15q14	GOLGA8B GOLGA8A DPH6	2.18e-04	61	87	3	chr15q14
GeneFamily	Phosphodiesterases	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	1.47e-10	24	61	6	681
GeneFamily	PDZ domain containing	WHRN MAST1 SIPA1 MAST2 PDZRN4	1.60e-04	152	61	5	1220
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	PDE4D MGAT5 CEP85L SRGAP3 DNAJC16 SRGAP1 PAK5 MAST1 GOLGA8B SORCS3 RUNX1T1 NEB GOLGA8A LRP1B PDZRN4	3.32e-06	1106	87	15	M39071
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Necab1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	WHRN PDE1C MOXD1 TBC1D4 EPYC UGDH	1.79e-07	126	87	6	a4fc7ac4931d2fc8aa8196a62d809b698937aa9c
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	WHRN PDE1C MOXD1 TBC1D4 UGDH CREB3L2	7.60e-07	161	87	6	bf70be1de418615b5442ec684552551edaf1f072
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PDE1C MOXD1 HECTD2 ADAM9 ZNF521 RUNX1T1	9.09e-07	166	87	6	65dafed953b01a9830b54309af75c7a561e88336
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Etv1_\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	WHRN PDE1C MOXD1 FSD2 CREB3L2	1.35e-06	97	87	5	f3c3fb260954f594a9ab8e1ac9a01115767cbc7a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 PDE3A TBC1D4 SRGAP3 SORCS3 LRP1B	1.65e-06	184	87	6	d33de57876817050b294f2ecb0a4eb0634cfa7f0
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 MGAT5 TBC1D4 SORCS3 LRP1B CREB3L2	1.82e-06	187	87	6	7ea8731288e2a99f45e3958590ee1d76f49ae888
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PDE3B PDE4D TBC1D4 CEP85L GOLGA8B GOLGA8A	2.05e-06	191	87	6	d9a6f61fcda4f5352488f7f55cb9b57aeacc717f
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PDE3B PDE4D HECTD2 SRGAP3 ZNF521 RUNX1T1	2.25e-06	194	87	6	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PDE3B PDE4D HECTD2 SRGAP3 ZNF521 RUNX1T1	2.31e-06	195	87	6	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	MOXD1 PDE4D HECTD2 SRGAP3 LOXL1 RUNX1T1	2.38e-06	196	87	6	1450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PDE1C MOXD1 PDE3A LRP1B MOGAT3 PDZRN4	2.38e-06	196	87	6	9830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCell	Bronchial-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MOXD1 PDE3A SRGAP1 ZNF521 RUNX1T1 PDZRN4	2.68e-06	200	87	6	389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell	Control_saline-Endothelial-Endothelial-Artery\|Control_saline / Treatment groups by lineage, cell group, cell type	PDE3A PDE4D NCKAP1 RABGAP1 RUNX1T1 GRPR	2.68e-06	200	87	6	65b71f1e8da5c3750fcd0a2e66d9ef3125a3f78a
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PDE1C MOXD1 UGDH RUNX1T1 CREB3L2	1.61e-05	161	87	5	dccb61d5e17a8f1c6d1fc146ee389f567659a0f0
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCNJL PDE3A HECTD2 SRGAP1 ADAMTS16	2.03e-05	169	87	5	87116c33c5ca8cb1862e103e5607b1df4d264569
ToppCell	LV\|World / Chamber and Cluster_Paper	PDE1C TBC1D4 FSD2 RUNX1T1 RNF207	2.75e-05	180	87	5	5ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCell	Control-Endothelial-Endothelial-Activated_Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE1C PDE3B CEP85L SRGAP1 ZNF521	2.97e-05	183	87	5	e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE1C ADAMTS16 NEB LRP1B DNAH11	3.05e-05	184	87	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 PDE3A TBC1D4 SRGAP3 LRP1B	3.05e-05	184	87	5	8fd8bd3d28d0ee6f0ef1f14e354d8eaf63a8081b
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE1C ADAMTS16 NEB LRP1B DNAH11	3.05e-05	184	87	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE1C ADAMTS16 NEB LRP1B DNAH11	3.05e-05	184	87	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PDE3B TBC1D4 GOLGA8B SORCS3 GOLGA8A	3.05e-05	184	87	5	5350b58aa9979631228835d11eb45ddf81d08bff
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PDE3B PDE4D TBC1D4 CEP85L GOLGA8A	3.13e-05	185	87	5	847257d232b9993cad50c814fd4ffeef52385295
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDE1C PDE3B PDE4D SRGAP3 ADAMTS16	3.13e-05	185	87	5	3d73b3e0bceb192257e5cfbe64b7ccb379b6e22d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3B PDE4D SRGAP3 ADAMTS16 LRP1B	3.21e-05	186	87	5	08632045d499e61dd96ff29a5a9a208afe58dc58
ToppCell	Control-Endothelial-Endothelial-Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE1C PDE3B PDE4B CEP85L ZNF521	3.30e-05	187	87	5	ea9d34bcd3bd1f36745846309ede349773de501a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE1C PDE3A RUNX1T1 DNAH11 PDZRN4	3.30e-05	187	87	5	ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE1C PDE3A RUNX1T1 DNAH11 PDZRN4	3.30e-05	187	87	5	530e4e6d91b5c0d9aa4543caa2b734a1674c5788
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 TBC1D4 SORCS3 LRP1B CREB3L2	3.38e-05	188	87	5	2ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3B PDE4D OVCH2 ADAMTS16 LRP1B	3.38e-05	188	87	5	4154f4787483c7e076e87a187733a9f666742c3d
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MOXD1 PDE3A LOXL1 SORCS3 RUNX1T1	3.47e-05	189	87	5	a153b83314cf52808f685296cff8c95af3f4983d
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	PDE1C PDE3A TBC1D4 FSD2 RNF207	3.47e-05	189	87	5	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	10x3'2.3-week_12-13-Mesenchymal_fibro-stroma-endosteal_fibroblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	LOXL1 PAK5 ADAMTS16 RUNX1T1 PDZRN4	3.47e-05	189	87	5	c392491aabe8a3e90974ab2ea123bbbe5200439d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 TBC1D4 ADAMTS16 SORCS3 LRP1B	3.47e-05	189	87	5	55420853f730b433ef58ac9337ac84ac78a247a0
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MOXD1 PDE4D SRGAP1 SORCS3 RUNX1T1	3.47e-05	189	87	5	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	PDE1C PDE3A TBC1D4 FSD2 RNF207	3.56e-05	190	87	5	de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	MOXD1 PDE3A ADAMTS16 RUNX1T1 LRP1B	3.56e-05	190	87	5	7986586b7c82e91c71102cc8c4d7a689ae63ab4d
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE1C PDE3A RUNX1T1 DNAH11 PDZRN4	3.56e-05	190	87	5	5681c211baeed4af82a2bbc13420f6a7b487581c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 MGAT5 TBC1D4 LRP1B CREB3L2	3.56e-05	190	87	5	3dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	PDE1C PDE3A TBC1D4 FSD2 RNF207	3.56e-05	190	87	5	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	PSB-critical-LOC-Epithelial-Ionocyte\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PDE1C MOXD1 TBC1D4 PAK5 RUNX1T1	3.65e-05	191	87	5	8f4637e801554e2343b974fe7794f01dd2151418
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MOXD1 PDE3A SRGAP1 SORCS3 RUNX1T1	3.65e-05	191	87	5	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	MOXD1 PDE3A ADAMTS16 RUNX1T1 LRP1B	3.65e-05	191	87	5	fa380a8752de158974b2ae5e741573439719cc0d
ToppCell	metastatic_Lymph_Node-Fibroblasts-Myofibroblasts\|metastatic_Lymph_Node / Location, Cell class and cell subclass	EPYC LOXL1 ADAMTS16 ZNF521 RUNX1T1	3.65e-05	191	87	5	aa43b472bc8362f79ae63f09f1ca764718bbf22c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE1C PDE3A RUNX1T1 DNAH11 PDZRN4	3.74e-05	192	87	5	24e2f15f5767a97eb3b389922bcfd7b13805e1ce
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	EPYC LOXL1 ADAMTS16 ZNF521 RUNX1T1	3.74e-05	192	87	5	67e845e513e76e820f55e2f0d15eb16f2944d05c
ToppCell	droplet-Heart-nan-18m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE1C TBC1D4 FSD2 RNF207 PDZRN4	3.74e-05	192	87	5	0bf99e029a06151092db1e8a0dcb45f4e688e771
ToppCell	COVID-19-kidney-CNT\|kidney / Disease (COVID-19 only), tissue and cell type	PDE1C PDE3B PDE4D ADAMTS16 LRP1B	3.74e-05	192	87	5	d32ae226d95b4b6adb99d14b602be09b661d4cd9
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PDE4B SRGAP3 SRGAP1 ZNF521 LRP1B	3.74e-05	192	87	5	d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 MGAT5 TBC1D4 LRP1B CREB3L2	3.74e-05	192	87	5	562df5e87038c500dd3a003fe5374cb31946b145
ToppCell	droplet-Heart-nan-18m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE1C TBC1D4 FSD2 RNF207 PDZRN4	3.74e-05	192	87	5	d766221acfce30cbf2c60b3ae40f6744968b952c
ToppCell	Control-Endothelial-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE1C PDE3B PDE4B CEP85L ZNF521	3.83e-05	193	87	5	aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCell	Control-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE1C PDE3B PDE4B CEP85L ZNF521	3.83e-05	193	87	5	c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MOXD1 PDE3A SRGAP1 SORCS3 RUNX1T1	3.83e-05	193	87	5	fb28717fadd06c3840636d25409ce80c9254bd34
ToppCell	Control-NK_CD56bright\|Control / Disease condition and Cell class	CCNJL WHRN SRGAP3 ZNF521 CDCP1	3.83e-05	193	87	5	8b1e7a226a6057e1097c1525984127b54e823876
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MOXD1 PDE3B HECTD2 SRGAP1 RUNX1T1	3.93e-05	194	87	5	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MOXD1 PDE3A SRGAP1 SORCS3 RUNX1T1	3.93e-05	194	87	5	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MOXD1 PDE3A SRGAP1 SORCS3 RUNX1T1	3.93e-05	194	87	5	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	MOXD1 PDE3A RUNX1T1 LRP1B RNF207	3.93e-05	194	87	5	85e00861c5068a27d0cf0ae677f420c8245baa9a
ToppCell	mild_COVID-19_(asymptomatic)-CD4+_Tcm\|World / disease group, cell group and cell class (v2)	PDE3B PDE4D ZBTB25 LOXL1 RNF207	4.02e-05	195	87	5	a72bb5b1b15dd1ab70ced5622d94499caff8bb6b
ToppCell	3'_v3-blood-Lymphocytic_NK-NK_CD56bright_CD16-\|blood / Manually curated celltypes from each tissue	CCNJL WHRN PDE4A TRAPPC10 GOLGA8A	4.02e-05	195	87	5	1470f562ebcfe7da367964ecfd6c7f43bcdb4a73
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-T_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PDE3B PDE4D ZBTB25 GOLGA8B GOLGA8A	4.12e-05	196	87	5	4a880a5d2c7047c050c7d6dd62186f35dc5c01f7
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PDE4D HECTD2 SRGAP3 LOXL1 RUNX1T1	4.22e-05	197	87	5	31a1852911bda38543916585fda34255fd62a134
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MOXD1 LOXL1 SRGAP1 RUNX1T1 CREB3L2	4.22e-05	197	87	5	85a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MOXD1 LOXL1 SRGAP1 RUNX1T1 CREB3L2	4.22e-05	197	87	5	e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MOXD1 PDE3A SRGAP1 RUNX1T1 CREB3L2	4.22e-05	197	87	5	9b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	HECTD2 SRGAP3 LOXL1 RUNX1T1 LRP1B	4.22e-05	197	87	5	0034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell	IPF-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	MOXD1 PDE3B PDE4D ZNF521 RUNX1T1	4.22e-05	197	87	5	f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 MGAT5 TBC1D4 NEB CREB3L2	4.33e-05	198	87	5	4448d13511485a44fe7b549e4b8b6ad7637db624
ToppCell	Tracheal-10x5prime-Stromal-Chondrocytic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PAPPA2 MOXD1 EPYC LRP1B PDZRN4	4.33e-05	198	87	5	c72ef2ddcbb6dacbed4c6200d89e17d57314dcdc
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MOXD1 PDE4D SRGAP3 LOXL1 RUNX1T1	4.33e-05	198	87	5	17dc055e2a289496d9c5cdbf3297bdf906dc6d22
ToppCell	Adult-Mesenchymal\|Adult / Lineage, Cell type, age group and donor	MOXD1 PDE3A SRGAP1 ZNF521 RUNX1T1	4.33e-05	198	87	5	26e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PDE1C MOXD1 PDE3A RUNX1T1 DNAH11	4.33e-05	198	87	5	c12e7511628db819a52959bb68580e27c00c2e41
ToppCell	Tracheal-10x5prime-Stromal-Chondrocytic-Chondrocyte\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PAPPA2 MOXD1 EPYC LRP1B PDZRN4	4.33e-05	198	87	5	55f013e9e6587d9ece59751fa131b1d22d6cceea
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PDE1C MOXD1 PDE3A LRP1B DNAH11	4.33e-05	198	87	5	22e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCell	Fetal_29-31_weeks-Mesenchymal\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MOXD1 PDE3A SRGAP1 ZNF521 RUNX1T1	4.33e-05	198	87	5	21cf4d81386761d09d0f6829c01c198e5524176d
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	PDE4D PAK5 MAST1 RUNX1T1 PDZRN4	4.43e-05	199	87	5	a255484ba77bd2741a541da278efc8cf4abbe570
ToppCell	Tracheal-NucSeq-Stromal-Chondrocytic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PDE3A EPYC ZNF521 LRP1B PDZRN4	4.54e-05	200	87	5	b5a54b9baf79aea01f76a161f0a39bbe87eb4945
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PDE1C PDE3A ZNF521 RUNX1T1 PDZRN4	4.54e-05	200	87	5	a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCell	Tracheal-NucSeq-Stromal-Chondrocytic-Chondrocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PDE3A EPYC ZNF521 LRP1B PDZRN4	4.54e-05	200	87	5	f5bd0b30e478dac09f68c46b0781f5f2e7e3c693
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PDE3A SRGAP1 ZNF521 RUNX1T1 PDZRN4	4.54e-05	200	87	5	74e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Nr2f2_Necab1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	WHRN PDE1C MOXD1 UGDH	1.03e-04	124	87	4	298ff8bd8f0459f44ce8a8aea889c6f1cf84ac5f
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gabrg1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SRGAP1 ADAMTS16 ALDOC CREB3L2	1.64e-04	140	87	4	2c44e8cc5190226049be7ebc465d685393e701c4
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crh_4930553C11Rik_\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MOXD1 OVCH2 SRGAP1 CREB3L2	1.68e-04	141	87	4	ad9a25569c142fb68ded34aeba0cd9be8124ce56
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Parm1-Excitatory_Neuron.Slc17a7.Parm1.Tshz2_(Deep_layer_pyramidal_cells--layer_5)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	PAPPA2 EPYC NLRP5	1.89e-04	57	87	3	d80eb5ade3c90344b67811e7f313c7d0720715f0
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Etv1_\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PDE1C MOXD1 UGDH CREB3L2	2.02e-04	148	87	4	4d43efee96a6493abd78e9ca41aab73db0c80626
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TBC1D4 SORCS3 ALDOC GRPR	2.08e-04	149	87	4	10ffd0051fb027bbebc662ca602c80d89bbf99c6
ToppCell	severe_COVID-19-Treg\|severe_COVID-19 / disease group, cell group and cell class (v2)	WHRN PDE3B TBC1D4 ACVR1	2.19e-04	151	87	4	bef8f31d5c4345a346fcf15db0fa36265ac304e7
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3B PDE4D ADAMTS16 LRP1B	2.30e-04	153	87	4	9b6675ace8a83c8d446b722301d0ec4e6840f3fc
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PDE3B TBC1D4 GOLGA8B GOLGA8A	2.30e-04	153	87	4	7480522a47e367f8facc4f5d599fbaf0b5ad4007
ToppCell	mild_COVID-19_(asymptomatic)-MAIT\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	WHRN PDE4D MAST1 GOLGA8A	2.30e-04	153	87	4	26852f3d8f80e102e24bcb90e24aac26fdc9a32c
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PDE3B TBC1D4 GOLGA8B GOLGA8A	2.47e-04	156	87	4	53ded973358e3e48054130131e959f0d1f4ef60f
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Kcne4\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PDE1C PDE3A ALDOC GRPR	2.47e-04	156	87	4	896e2d958be0a5c62fb6eebad2dfb7e1ce69f3ad
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3B PDE4D ADAMTS16 CDCP1	2.54e-04	157	87	4	2c5295043611bac7dfa4aef2146681bce4a33a8f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MOXD1 PDE3A MOB3C RUNX1T1	2.66e-04	159	87	4	e812cbde59188924c6277c3feadf1a9592fa62a4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MOXD1 PDE3A MOB3C RUNX1T1	2.66e-04	159	87	4	2607b562903228274fbd96168ba826782fab0b53
ToppCell	LAM-Lymphoid-B-cell-2\|LAM / Condition, Lineage and Cell class	WHRN MOXD1 PDE4B CREB3L2	2.73e-04	160	87	4	0060c2b3304f411c682aa2ba20bcf80f346d2403
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MOXD1 TBC1D4 UGDH CREB3L2	2.73e-04	160	87	4	dd16ca90feb3ae88b6409d6c278b4765da565514
ToppCell	Basal_cells-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	SRGAP3 PAK5 GOLGA8A LRP1B	2.73e-04	160	87	4	b223cc47e68a29df4758c5ccf8f6dbffe2a6fa1d
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Kcne4\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PDE3A ALDOC GRPR PDZRN4	2.79e-04	161	87	4	be77e99faf653480c166305df3a4e93db76f0dcb
Drug	trequinsin	PDE3A PDE3B PDE4A PDE4B PDE4D	8.51e-11	9	86	5	ctd:C035964
Drug	L-826,141	PDE3A PDE3B PDE4A PDE4B PDE4D	8.51e-11	9	86	5	ctd:C459562
Drug	AA-2379	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	1.26e-10	21	86	6	CID000128390
Drug	HWA 153	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	1.73e-10	22	86	6	CID000162797
Drug	atherosperminine	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	2.33e-10	23	86	6	CID000096918
Drug	griseolic acid	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	2.33e-10	23	86	6	CID000127607
Drug	Ro 15-2041	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	5.27e-10	26	86	6	CID000132434
Drug	desethyl KBT-3022	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	5.27e-10	26	86	6	CID000127736
Drug	T-440	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	5.27e-10	26	86	6	CID000177965
Drug	Ibudilast	PDE3A PDE4A PDE4B PDE4D	9.46e-10	5	86	4	DB05266
Drug	imidazole-4-carboxamide	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	2.04e-09	32	86	6	CID000152917
Drug	dyphylline	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	2.48e-09	33	86	6	CID000003182
Drug	Roflumilast	PDE3A PDE3B PDE4A PDE4B PDE4D	2.89e-09	16	86	5	ctd:C424423
Drug	AH 21-132	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	5.15e-09	37	86	6	CID003035793
Drug	CI-930	PDE1C PDE3A PDE3B PDE4B PDE4D	1.01e-08	20	86	5	CID003021728
Drug	bemoradan	PDE3A PDE3B PDE4B PDE4D	1.31e-08	8	86	4	CID005362399
Drug	denbufylline	PDE3A PDE3B PDE4A PDE4B PDE4D	2.75e-08	24	86	5	CID000002984
Drug	4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid	PDE4A PDE4B PDE4D	5.20e-08	3	86	3	DB08299
Drug	roflumilast	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	1.26e-07	62	86	6	CID000449193
Drug	zardaverine	PDE3A PDE3B PDE4A PDE4B PDE4D	2.03e-07	35	86	5	CID000005723
Drug	Piclamilast	PDE4A PDE4B PDE4D	2.08e-07	4	86	3	DB01791
Drug	Quazinona	PDE3A PDE3B PDE4B PDE4D	4.35e-07	17	86	4	CID000005000
Drug	Org 9935	PDE3A PDE3B PDE4B PDE4D	4.35e-07	17	86	4	CID000131100
Drug	NSC18930	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	4.65e-07	77	86	6	CID000001189
Drug	D-22888	PDE4A PDE4B PDE4D	5.17e-07	5	86	3	CID000197714
Drug	1,7-naphthyridine	PDE4A PDE4B PDE4D	5.17e-07	5	86	3	CID000009209
Drug	DTIC	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	6.30e-07	81	86	6	CID005281007
Drug	AC1L73CW	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	7.81e-07	84	86	6	CID000328776
Drug	Carteolol hydrochloride [51781-21-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A	WHRN MOXD1 PDE4A EPYC RABGAP1 SIPA1 RUNX1T1 MAST2	9.10e-07	200	86	8	4176_UP
Drug	chloroacetol phosphate	UGDH ALDOA ALDOC	1.03e-06	6	86	3	CID000168137
Drug	siguazodan	PDE3A PDE3B PDE4B PDE4D	1.32e-06	22	86	4	CID000072124
Drug	Theophylline	PDE3A PDE4A PDE4B	1.80e-06	7	86	3	DB00277
Drug	Iloprost	PDE4A PDE4B PDE4D	1.80e-06	7	86	3	DB01088
Drug	Ketotifen	PDE4A PDE4B PDE4D	1.80e-06	7	86	3	DB00920
Drug	trequinsin	PDE1C PDE3A PDE3B PDE4B PDE4D	2.68e-06	58	86	5	CID000005537
Drug	SCH 51866	PDE1C PDE4B PDE4D	2.87e-06	8	86	3	CID005311355
Drug	KF18280	PDE4A PDE4B PDE4D	2.87e-06	8	86	3	CID003071941
Drug	Dyphylline	PDE4A PDE4B PDE4D	2.87e-06	8	86	3	DB00651
Drug	Ro-1724	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	3.81e-06	110	86	6	CID000005087
Drug	motapizone	PDE3A PDE4A PDE4B PDE4D	4.19e-06	29	86	4	CID000065819
Drug	PF-04254644	PDE1C PDE3A PDE3B	4.30e-06	9	86	3	ctd:C551178
Drug	PDEs	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	5.18e-06	116	86	6	CID003036959
Drug	NVP ABE171	PDE4A PDE4B PDE4D	6.13e-06	10	86	3	ctd:C451724
Drug	cilostamide	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	6.30e-06	120	86	6	CID000002753
Drug	ibudilast	PDE3A PDE4A PDE4B PDE4D	7.14e-06	33	86	4	CID000003671
Drug	RS-1893	PDE3A PDE3B	1.41e-05	2	86	2	CID000128386
Drug	M 98	PDE4B PDE4D	1.41e-05	2	86	2	CID006420180
Drug	V11294 Analogue 5f	PDE4B PDE4D	1.41e-05	2	86	2	CID011214587
Drug	V11294 Analogue 5i	PDE4B PDE4D	1.41e-05	2	86	2	CID011376249
Drug	V11294 Analogue 5t	PDE4B PDE4D	1.41e-05	2	86	2	CID011226695
Drug	V11294 Analogue 5e	PDE4B PDE4D	1.41e-05	2	86	2	CID011443441
Drug	V11294 Analogue 5d	PDE4B PDE4D	1.41e-05	2	86	2	CID011283750
Drug	V11294 Analogue 5n	PDE4B PDE4D	1.41e-05	2	86	2	CID011238279
Drug	3-cyclopentyloxy-4-methoxybenzoic acid	PDE4B PDE4D	1.41e-05	2	86	2	CID002779323
Drug	V11294 Analogue 5v	PDE4B PDE4D	1.41e-05	2	86	2	CID011375325
Drug	V11294 Analogue 5p	PDE4B PDE4D	1.41e-05	2	86	2	CID011478659
Drug	3-cyclopentyloxy-4-methoxybenzaldehyde	PDE4B PDE4D	1.41e-05	2	86	2	CID002735893
Drug	V11294 Analogue 5o	PDE4B PDE4D	1.41e-05	2	86	2	CID011249748
Drug	V11294 Analogue 5c	PDE4B PDE4D	1.41e-05	2	86	2	CID011179896
Drug	V11294 Analogue 5b	PDE4B PDE4D	1.41e-05	2	86	2	CID011443760
Drug	Cis-4-Cyano-4-[3-(Cyclopentyloxy)-4-Methoxyphenyl]Cyclohexanecarboxylic Acid	PDE4B PDE4D	1.41e-05	2	86	2	DB03849
Drug	T-2585.HCl	PDE4B PDE4D	1.41e-05	2	86	2	CID006918355
Drug	Np-V	PDE4B PDE4D	1.41e-05	2	86	2	CID009999276
Drug	V11294 Analogue 5m	PDE4B PDE4D	1.41e-05	2	86	2	CID011477773
Drug	(S)-Rolipram	PDE4B PDE4D	1.41e-05	2	86	2	DB03606
Drug	1-((5-(1-aminoethyl)-2-(8-methoxy-2-(triflurormethyl)-5-quinolinyl)-4-oxazolyl) carbonyl)-4-((cyclopropylcarbonyl)amino)proline ethyl ester	PDE4B PDE4D	1.41e-05	2	86	2	ctd:C554440
Drug	Ichiba acid	ALDOA ALDOC	1.41e-05	2	86	2	CID000440403
Drug	3-HM	ALDOA ALDOC	1.41e-05	2	86	2	CID000439464
Drug	V11294 Analogue 8a	PDE4B PDE4D	1.41e-05	2	86	2	CID011442865
Drug	bromohydroxyacetone phosphate	ALDOA ALDOC	1.41e-05	2	86	2	CID000152675
Drug	V11294 Analogue 5r	PDE4B PDE4D	1.41e-05	2	86	2	CID011168555
Drug	V11294 Analogue 5j	PDE4B PDE4D	1.41e-05	2	86	2	CID011433797
Drug	V11294 Analogue 5q	PDE4B PDE4D	1.41e-05	2	86	2	CID011318772
Drug	V11294 Analogue 5a	PDE4B PDE4D	1.41e-05	2	86	2	CID011386897
Drug	V11294 Analogue 5k	PDE4B PDE4D	1.41e-05	2	86	2	CID011456440
Drug	anthracene diol	ALDOA ALDOC	1.41e-05	2	86	2	CID000155464
Drug	Inocor (TN)	PDE3A PDE3B	1.41e-05	2	86	2	CID000656683
Drug	V11294 Analogue 5h	PDE4B PDE4D	1.41e-05	2	86	2	CID011306698
Drug	3,5-Dimethyl-1-(3-Nitrophenyl)-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester	PDE4B PDE4D	1.41e-05	2	86	2	DB01959
Drug	4-[3-(Cyclopentyloxy)-4-Methoxyphenyl]-2-Pyrrolidinone	PDE4B PDE4D	1.41e-05	2	86	2	DB01954
Drug	(R)-Rolipram	PDE4B PDE4D	1.41e-05	2	86	2	DB04149
Drug	(4R)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one	PDE4A PDE4D	1.41e-05	2	86	2	DB06842
Drug	RP 73401	PDE3A PDE4A PDE4B PDE4D	1.41e-05	39	86	4	CID000154575
Drug	OPC 3911	PDE1C PDE3A PDE3B	1.45e-05	13	86	3	CID000131164
Drug	zaprinast	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	1.59e-05	141	86	6	CID000005722
Drug	beta-isopropyl-tropolone	CPA4 ALDOA ALDOC	1.84e-05	14	86	3	CID000080297
Drug	cilostazol	PDE1C PDE3A PDE3B PDE4B PDE4D	1.87e-05	86	86	5	CID000002754
Drug	EHNA	PDE1C PDE3A PDE3B PDE4B PDE4D	1.98e-05	87	86	5	CID000003206
Drug	hypoxanthine	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D PSMA3	2.01e-05	220	86	7	CID000000790
Drug	amrinone	PDE3A PDE3B PDE4B PDE4D	2.09e-05	43	86	4	CID000003698
Drug	vanadyl	PDE1C PDE3A PDE3B PDE4A PTPN11 PDE4B PDE4D DNAH11	2.13e-05	307	86	8	CID000061671
Drug	milrinone	PDE1C PDE3A PDE3B PDE4A PDE4B PDE4D	2.25e-05	150	86	6	CID000004197
Drug	CDP840	PDE4A PDE4B PDE4D	2.81e-05	16	86	3	CID000127928
Drug	8 mm x	PDE1C PDE4B PDE4D	3.41e-05	17	86	3	CID000155806
Drug	rutin	PDE4B PDE4D SRGAP3 ALDOA ALDOC	3.52e-05	98	86	5	CID005280805
Drug	orthovanadate	PDE1C PDE3A PDE3B PDE4A PTPN11 PDE4B PDE4D CDCP1 DNAH11	3.91e-05	435	86	9	CID000061672
Drug	Cilomilast	PDE4A PDE4B PDE4D	4.08e-05	18	86	3	ctd:C433247
Drug	SureCN4406168	PDE3A PDE3B	4.22e-05	3	86	2	CID011502028
Drug	Org 4428	PDE4B PDE4D	4.22e-05	3	86	2	CID000166560
Drug	SureCN4398032	PDE3A PDE3B	4.22e-05	3	86	2	CID011532088
Disease	age at first sexual intercourse measurement	PDE1C PDE4B ZNF521 SORCS3 DGKZ RUNX1T1 HARBI1 PDZRN4	1.51e-05	383	85	8	EFO_0009749
Disease	body weight	DOCK1 PAPPA2 PDE1C MOXD1 NAA25 PDE4B PAK5 ZNF521 RABGAP1 RUNX1T1 PRMT7 LRP1B PDZRN4	6.29e-05	1261	85	13	EFO_0004338
Disease	sleep efficiency	GOLGA8B GOLGA8A	8.15e-05	5	85	2	EFO_0803364
Disease	visceral heterotaxy (implicated_via_orthology)	MEGF8 OSBPL1A DNAH11	1.67e-04	37	85	3	DOID:0050545 (implicated_via_orthology)
Disease	exfoliation syndrome (is_implicated_in)	LOXL1 ACVR1	1.71e-04	7	85	2	DOID:13641 (is_implicated_in)
Disease	urgency urinary incontinence	ADAMTS16 ZNF521	5.31e-04	12	85	2	EFO_0006865
Disease	parental longevity	PDE3A NAA25 PTPN11 PDE4B MGAT5 LRP1B TSEN2	5.66e-04	494	85	7	EFO_0007796
Disease	pulse pressure measurement	PAPPA2 PDE3A MEGF8 NCKAP1 LOXL1 SORCS3 RABGAP1 SIPA1 SNRNP70 MAST2 RNF207 CREB3L2	6.29e-04	1392	85	12	EFO_0005763
Disease	waist-hip ratio	PAPPA2 MEGF8 SRGAP3 LOXL1 XRN1 ABTB1 ACVR1 SIPA1 TSEN2 MOGAT3 PDZRN4	7.77e-04	1226	85	11	EFO_0004343
Disease	sphingomyelin 14:0 measurement	PDE4D PAK5	1.08e-03	17	85	2	EFO_0010390
Disease	gut microbiome measurement, bone density	DOCK1 SORCS3 RABGAP1	1.50e-03	78	85	3	EFO_0003923, EFO_0007874
Disease	sucrose liking measurement	GOLGA8B GOLGA8A	1.51e-03	20	85	2	EFO_0010157
Disease	N-glycan measurement	MGAT5 MOGAT3	1.82e-03	22	85	2	EFO_0004999
Disease	serum iron measurement	MGAT5 SRGAP3 LRP1B	1.99e-03	86	85	3	EFO_0006332
Disease	primary open angle glaucoma (is_implicated_in)	LOXL1 ACVR1	1.99e-03	23	85	2	DOID:1070 (is_implicated_in)
Disease	Cerebral Astrocytoma	PTPN11 ACVR1	2.36e-03	25	85	2	C0750935
Disease	Intracranial Astrocytoma	PTPN11 ACVR1	2.36e-03	25	85	2	C0750936
Disease	Pilocytic Astrocytoma	PTPN11 ACVR1	2.36e-03	25	85	2	C0334583
Disease	Astrocytoma	PTPN11 ACVR1	2.36e-03	25	85	2	C0004114
Disease	Juvenile Pilocytic Astrocytoma	PTPN11 ACVR1	2.36e-03	25	85	2	C0280783
Disease	Diffuse Astrocytoma	PTPN11 ACVR1	2.36e-03	25	85	2	C0280785
Disease	response to gemcitabine	DOCK1 MGAT5	2.36e-03	25	85	2	GO_0036272
Disease	Grade I Astrocytoma	PTPN11 ACVR1	2.36e-03	25	85	2	C1704230
Disease	Subependymal Giant Cell Astrocytoma	PTPN11 ACVR1	2.36e-03	25	85	2	C0205768
Disease	Mixed oligoastrocytoma	PTPN11 ACVR1	2.36e-03	25	85	2	C0547065
Disease	Childhood Cerebral Astrocytoma	PTPN11 ACVR1	2.36e-03	25	85	2	C0338070
Disease	Ischemic stroke	PDE3A EFCAB12 OSBPL1A DNAH11 PDZRN4	2.48e-03	324	85	5	HP_0002140
Disease	Neurodevelopmental Disorders	PTPN11 NCKAP1 SRGAP3	2.48e-03	93	85	3	C1535926
Disease	gout	PDE1C NAA25 MGAT5 RUNX1T1	2.51e-03	196	85	4	EFO_0004274
Disease	Gemistocytic astrocytoma	PTPN11 ACVR1	2.55e-03	26	85	2	C0334581
Disease	Protoplasmic astrocytoma	PTPN11 ACVR1	2.55e-03	26	85	2	C0334580
Disease	Fibrillary Astrocytoma	PTPN11 ACVR1	2.55e-03	26	85	2	C0334582
Disease	Anaplastic astrocytoma	PTPN11 ACVR1	2.75e-03	27	85	2	C0334579
Disease	FEV/FEC ratio	PDE1C PDE3A MGAT5 SRGAP3 ACVR1 RUNX1T1 NEB ZBTB42 TSEN2 GRPR	2.77e-03	1228	85	10	EFO_0004713

Protein segments in the cluster

Peptide	Gene	Start	Entry
AAVYKALSDHHVYLE	ALDOC	211	P09972
SHVYAVIEDTMVYGH	CDCP1	731	Q9H5V8
AAVYKALSDHHIYLE	ALDOA	211	P04075
DSYMYQTVGHHAIDL	DPH6	46	Q7L8W6
LITHYHEMGSLYDYL	ACVR1	281	Q04771
HLAVYLLDHFMDRYN	CCNJL	61	Q8IV13
IEYYLSEAVHETDLH	CCNJ	151	Q5T5M9
SQYLDYIHVMTYDLH	CHIA	201	Q9BZP6
HFLLYGHAVSSDEMD	DNAH11	1051	Q96DT5
HLEYFEEAMNYLLSH	ACOT2	266	P49753
REAMYHSAEHGYVDV	BTBD11	796	A6QL63
MDDDYEAYHSLFLSL	EFCAB12	1	Q6NXP0
YEVDHRGDYVSHEIM	ADAMTS16	66	Q8TE57
LHPMEHEFYEDNEYI	PDZRN4	371	Q6ZMN7
YHHDNVVDMYSSYLV	PAK5	501	Q9P286
NHFLDISLEAHMYAS	RABGAP1	711	Q9Y3P9
HIEHNSRITGMDVYY	LRP1B	3916	Q9NZR2
YDTHSLMHKLSPEEY	TMBIM4	196	Q9HC24
LDIIHTYMEVHATVY	MGAT5	466	Q09328
RLDDMAIAHHYRDSY	RUNX1T1	301	Q06455
YNSTLDHIDLMEEYH	HECTD2	341	Q5U5R9
HYHSMDEFSHYDLLD	LOXL1	451	Q08397
EYRYNMAHSATHSVI	HARBI1	246	Q96MB7
MYDLHHLYLTDNNLD	EPYC	236	Q99645
MVLSHSYCYHVDLIQ	OR51F2	186	Q8NH61
MHAADVTQTVHYLLY	PDE1C	231	Q14123
LMALYVAAAMHDYDH	PDE3A	826	Q14432
LMALYVAAAMHDYDH	PDE3B	811	Q13370
VTYMLTLEDHYHADV	PDE4A	416	P27815
DTFITYMMTLEDHYH	PDE4B	386	Q07343
TYLMTLEDHYHADVA	PDE4D	446	Q08499
DSIDEKYLLHFSHYV	DNAJC16	136	Q9Y2G8
DYHLDYCSMYTDHSV	MEGF8	556	Q7Z7M0
HMNILLPDSHCEEYY	NLRP5	566	P59047
FATLAELVQYYMEHH	PTPN11	71	Q06124
VIRVDSHLHTTMYYF	OR10G8	46	Q8NGN5
TEYMEHTYLIHKASS	OSBPL1A	581	Q9BXW6
NYAHEMTHGASDREY	NCKAP1	161	Q9Y2A7
VYMGDTDVYSVHHIV	MAST1	986	Q9Y2H9
EEVNHYHALYMTALE	MOGAT3	306	Q86VF5
HVAATYDGRHMALYV	PAPPA2	366	Q9BXP8
SLASIHYMRSHYQEA	TTC26	156	A0AVF1
TAILRQMEDYHYAHL	DOCK1	936	Q14185
SPHQMYVDHYRSLEE	ELOA	211	Q14241
YHQEIARSSYADMLH	PRMT7	26	Q9NVM4
GAYHSLEAIYHEMDN	CPA4	121	Q9UI42
YRSYHYSEVDTSMLH	GRPR	286	P30550
SHFEHIIYRMDDVYK	ADAM9	156	Q13443
HAMLGHYVNCEDSYV	CEP85L	401	Q5SZL2
IRVYMGDSDVYTVHH	MAST2	1121	Q6P0Q8
VSMHDYEALHYDKEQ	DGKZ	651	Q13574
LYHMKHSLRYFEEES	GOLGA8B	141	A8MQT2
FERYHEDAHMLDTQY	HELZ2	2411	Q9BYK8
MDAALHYYELARDHF	IFT140	971	Q96RY7
MYHTHFSELLDEFSQ	CREB3L2	31	Q70SY1
YIHHFDSILSMGAEA	MOB3C	166	Q70IA8
HAMDTLYRHSYDLSS	MTA3	236	Q9BTC8
NTDLYHMKHSLRYFE	GOLGA8A	166	A7E2F4
YAFIEYEHERDMHSA	SNRNP70	146	P08621
YEHERDMHSAYKHAD	SNRNP70	151	P08621
YHASYSVIIELVDDH	TSEN2	376	Q8NCE0
HYEDSYRHLQAEMQS	RNF207	426	Q6ZRF8
KTYHMYHAESISAES	SRGAP1	166	Q7Z6B7
HMEVRTTDGYAHYLT	SORCS3	356	Q9UPU3
DVESCHHSYLSMYSL	OVCH2	361	Q7RTZ1
FYHMDLYDSEDRLHL	FSD2	21	A1L4K1
GTHSLYTTYQDHEIM	SIPA1	391	Q96FS4
RHLLNEQEHATMAYY	WHRN	431	Q9P202
LAMDYVSIINYLHHS	POMK	181	Q9H5K3
THVLYYMYSDHTELS	ABTB1	331	Q969K4
FLHADYLSHIATEMN	ZBTB25	101	P24278
IYISKYLMDEGAHLH	UGDH	351	O60701
HATHKHYMTREADEY	TRIM77	121	I1YAP6
HLLSAMSQETYLYHI	VPS35L	826	Q7Z3J2
NHLSFILYYHREDME	TM9SF4	181	Q92544
YHLEYAMENSTHTII	MOXD1	106	Q6UVY6
TYHMYHAESISAESK	SRGAP3	166	O43295
SESFHTVEELYSHMD	ZNF521	316	Q96K83
YQETYIDDLGHLHVM	ZDHHC4	226	Q9NPG8
LLASHGDTEHMVYFA	VPS18	546	Q9P253
FHLLHLSLMREYIDY	XRN1	246	Q8IZH2
HLADRVAMYVHAYTL	PSMA3	111	P25788
MDISKQLHAYEVEYH	TBC1D4	1166	O60343
DVHNFCITYHYDHMS	TMEM262	36	E9PQX1
EDVLAAASYLHMYDI	ZBTB42	96	B2RXF5
LIHTGEMSYRHNIYE	ZNF112	351	Q9UJU3
KHYLDLSHATIEMYT	TRAPPC10	456	P48553
LYLLVDHFMELYHQS	TTI1	501	O43156
NSEEYHSHLFMAYAR	NAA25	111	Q14CX7
HHYTYLPDAMDLELS	NEB	1166	P20929