Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	phosphatidylethanolamine binding	GABARAP GABARAPL3 GABARAPL1	2.63e-06	19	29	3	GO:0008429
GeneOntologyMolecularFunction	GABA receptor binding	GABARAP GABARAPL3 GABARAPL1	3.09e-06	20	29	3	GO:0050811
GeneOntologyMolecularFunction	histone H3K4 monomethyltransferase activity	KMT2C KMT2D	5.67e-05	8	29	2	GO:0140945
GeneOntologyMolecularFunction	histone H3K4 trimethyltransferase activity	KMT2C KMT2D	9.10e-05	10	29	2	GO:0140999
GeneOntologyMolecularFunction	histone modifying activity	PRKCB KMT2C KMT2D KAT14	3.19e-04	229	29	4	GO:0140993
GeneOntologyMolecularFunction	histone H3K4 methyltransferase activity	KMT2C KMT2D	3.81e-04	20	29	2	GO:0042800
GeneOntologyMolecularFunction	histone binding	PRKCB SMARCA5 CBX6 CBX8	5.55e-04	265	29	4	GO:0042393
GeneOntologyMolecularFunction	ubiquitin-protein transferase regulator activity	RPL5 CBX8	1.18e-03	35	29	2	GO:0055106
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	SMARCA5 EP400	1.31e-03	37	29	2	GO:0140658
GeneOntologyMolecularFunction	ubiquitin protein ligase binding	GABARAP GABARAPL3 GABARAPL1 RPL5	1.36e-03	337	29	4	GO:0031625
GeneOntologyMolecularFunction	ubiquitin-like protein ligase binding	GABARAP GABARAPL3 GABARAPL1 RPL5	1.69e-03	358	29	4	GO:0044389
GeneOntologyMolecularFunction	histone H3 methyltransferase activity	KMT2C KMT2D	1.86e-03	44	29	2	GO:0140938
GeneOntologyMolecularFunction	beta-tubulin binding	GABARAP GABARAPL1	2.30e-03	49	29	2	GO:0048487
GeneOntologyMolecularFunction	chromatin binding	PRKCB SMARCA5 EP400 CBX6 CBX8	3.89e-03	739	29	5	GO:0003682
GeneOntologyMolecularFunction	protein-lysine N-methyltransferase activity	KMT2C KMT2D	4.37e-03	68	29	2	GO:0016279
GeneOntologyMolecularFunction	lysine N-methyltransferase activity	KMT2C KMT2D	4.50e-03	69	29	2	GO:0016278
GeneOntologyMolecularFunction	histone methyltransferase activity	KMT2C KMT2D	4.76e-03	71	29	2	GO:0042054
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	SMARCA5 EP400 DCLRE1C	6.34e-03	262	29	3	GO:0140097
GeneOntologyBiologicalProcess	cellular response to nitrogen levels	GABARAP GABARAPL3 GABARAPL1	6.05e-07	12	30	3	GO:0043562
GeneOntologyBiologicalProcess	cellular response to nitrogen starvation	GABARAP GABARAPL3 GABARAPL1	6.05e-07	12	30	3	GO:0006995
GeneOntologyBiologicalProcess	chromatin organization	PRKCB KMT2C SMARCA5 KMT2D EP400 CBX6 KAT14 CBX8	3.07e-05	896	30	8	GO:0006325
GeneOntologyBiologicalProcess	protein-DNA complex organization	PRKCB KMT2C SMARCA5 KMT2D EP400 CBX6 KAT14 CBX8	6.64e-05	999	30	8	GO:0071824
GeneOntologyBiologicalProcess	chromatin remodeling	PRKCB KMT2C SMARCA5 KMT2D EP400 KAT14 CBX8	7.42e-05	741	30	7	GO:0006338
GeneOntologyBiologicalProcess	autophagosome maturation	GABARAP GABARAPL3 GABARAPL1	1.36e-04	69	30	3	GO:0097352
GeneOntologyCellularComponent	autophagosome membrane	GABARAP GABARAPL3 GABARAPL1	7.41e-05	57	30	3	GO:0000421
GeneOntologyCellularComponent	MLL3/4 complex	KMT2C KMT2D	1.30e-04	12	30	2	GO:0044666
GeneOntologyCellularComponent	PRC1 complex	CBX6 CBX8	3.35e-04	19	30	2	GO:0035102
GeneOntologyCellularComponent	heterochromatin	SMARCA5 CBX6 CBX8	4.04e-04	101	30	3	GO:0000792
GeneOntologyCellularComponent	autophagosome	GABARAP GABARAPL3 GABARAPL1	6.53e-04	119	30	3	GO:0005776
GeneOntologyCellularComponent	GABA-ergic synapse	GABRG3 GABARAP RPS6	1.65e-03	164	30	3	GO:0098982
GeneOntologyCellularComponent	transferase complex	KMT2C KMT2D EP400 CBX6 KAT14 CBX8	2.16e-03	963	30	6	GO:1990234
GeneOntologyCellularComponent	nuclear ubiquitin ligase complex	CBX6 CBX8	2.25e-03	49	30	2	GO:0000152
GeneOntologyCellularComponent	intracellular protein-containing complex	EP400 DCLRE1C CBX6 KAT14 RPL5 CBX8	2.26e-03	972	30	6	GO:0140535
GeneOntologyCellularComponent	PcG protein complex	CBX6 CBX8	2.52e-03	52	30	2	GO:0031519
GeneOntologyCellularComponent	nuclear protein-containing complex	KMT2C SP100 SMARCA5 KMT2D EP400 CBX6 CBX8	2.82e-03	1377	30	7	GO:0140513
GeneOntologyCellularComponent	dendrite membrane	GABRG3 GABARAPL1	2.92e-03	56	30	2	GO:0032590
HumanPheno	Aplasia of the thymus	KMT2D DCLRE1C	2.08e-05	4	10	2	HP:0005359
HumanPheno	Natal tooth	KMT2C KMT2D VARS1	4.43e-05	38	10	3	HP:0000695
HumanPheno	Aplasia/Hypoplasia of the thymus	KMT2D DCLRE1C PI4KA	6.45e-05	43	10	3	HP:0010515
HumanPheno	Advanced eruption of teeth	KMT2C KMT2D VARS1	7.91e-05	46	10	3	HP:0006288
HumanPheno	Bilateral conductive hearing impairment	KMT2D VARS1	9.65e-05	8	10	2	HP:0008513
HumanPheno	Ankle flexion contracture	NEB VARS1 PI4KA	1.43e-04	56	10	3	HP:0006466
HumanPheno	Kyphosis	KMT2C MESD KMT2D GZF1 NEB PI4KA	1.45e-04	510	10	6	HP:0002808
HumanPheno	Conductive deafness	KMT2D VARS1	1.55e-04	10	10	2	HP:0000367
HumanPheno	Abnormal thymus morphology	KMT2D DCLRE1C PI4KA	1.59e-04	58	10	3	HP:0000777
HumanPheno	Ankle contracture	NEB VARS1 PI4KA	1.76e-04	60	10	3	HP:0034677
Domain	Atg8-like	GABARAP GABARAPL3 GABARAPL1	1.87e-07	8	29	3	IPR004241
Domain	Atg8	GABARAP GABARAPL3 GABARAPL1	1.87e-07	8	29	3	PF02991
Domain	FYrich_C	KMT2C KMT2D	2.32e-05	5	29	2	IPR003889
Domain	FYrich_N	KMT2C KMT2D	2.32e-05	5	29	2	IPR003888
Domain	FYRC	KMT2C KMT2D	2.32e-05	5	29	2	SM00542
Domain	FYRN	KMT2C KMT2D	2.32e-05	5	29	2	SM00541
Domain	FYRN	KMT2C KMT2D	2.32e-05	5	29	2	PF05964
Domain	FYRC	KMT2C KMT2D	2.32e-05	5	29	2	PF05965
Domain	FYRC	KMT2C KMT2D	2.32e-05	5	29	2	PS51543
Domain	FYRN	KMT2C KMT2D	2.32e-05	5	29	2	PS51542
Domain	CBX7_C	CBX6 CBX8	2.32e-05	5	29	2	PF17218
Domain	CBX7_C	CBX6 CBX8	2.32e-05	5	29	2	IPR033773
Domain	HMG_box	KMT2C SP100 KMT2D	7.48e-05	53	29	3	PF00505
Domain	HMG	KMT2C SP100 KMT2D	7.92e-05	54	29	3	SM00398
Domain	HMG_box_dom	KMT2C SP100 KMT2D	1.38e-04	65	29	3	IPR009071
Domain	Post-SET_dom	KMT2C KMT2D	2.76e-04	16	29	2	IPR003616
Domain	PostSET	KMT2C KMT2D	2.76e-04	16	29	2	SM00508
Domain	POST_SET	KMT2C KMT2D	2.76e-04	16	29	2	PS50868
Domain	Chromodomain_CS	CBX6 CBX8	3.51e-04	18	29	2	IPR023779
Domain	EPHD	KMT2C KMT2D	5.27e-04	22	29	2	PS51805
Domain	Chromo_domain	CBX6 CBX8	6.29e-04	24	29	2	IPR023780
Domain	Chromo	CBX6 CBX8	7.39e-04	26	29	2	PF00385
Domain	CHROMO_2	CBX6 CBX8	8.58e-04	28	29	2	PS50013
Domain	CHROMO_1	CBX6 CBX8	8.58e-04	28	29	2	PS00598
Domain	SNF2_N	SMARCA5 EP400	1.12e-03	32	29	2	PF00176
Domain	SNF2_N	SMARCA5 EP400	1.12e-03	32	29	2	IPR000330
Domain	Chromodomain-like	CBX6 CBX8	1.12e-03	32	29	2	IPR016197
Domain	CHROMO	CBX6 CBX8	1.19e-03	33	29	2	SM00298
Domain	Chromo/shadow_dom	CBX6 CBX8	1.19e-03	33	29	2	IPR000953
Domain	DNA/RNA_helicase_DEAH_CS	SMARCA5 EP400	1.34e-03	35	29	2	IPR002464
Domain	DEAH_ATP_HELICASE	SMARCA5 EP400	1.58e-03	38	29	2	PS00690
Domain	MYB_LIKE	SMARCA5 EP400	1.58e-03	38	29	2	PS50090
Domain	SET	KMT2C KMT2D	1.84e-03	41	29	2	PF00856
Domain	BTB	KCTD20 GZF1 BTBD10	1.91e-03	160	29	3	PS50097
Domain	SET	KMT2C KMT2D	2.31e-03	46	29	2	SM00317
Domain	BTB	KCTD20 GZF1 BTBD10	2.68e-03	180	29	3	SM00225
Domain	SET_dom	KMT2C KMT2D	2.72e-03	50	29	2	IPR001214
Domain	SANT	SMARCA5 EP400	2.72e-03	50	29	2	SM00717
Domain	SET	KMT2C KMT2D	2.72e-03	50	29	2	PS50280
Domain	BTB/POZ_dom	KCTD20 GZF1 BTBD10	2.89e-03	185	29	3	IPR000210
Domain	SANT/Myb	SMARCA5 EP400	2.94e-03	52	29	2	IPR001005
Domain	BTB_2	KCTD20 BTBD10	3.05e-03	53	29	2	PF02214
Domain	T1-type_BTB	KCTD20 BTBD10	3.05e-03	53	29	2	IPR003131
Domain	SKP1/BTB/POZ	KCTD20 GZF1 BTBD10	3.07e-03	189	29	3	IPR011333
Domain	-	SP100 KMT2D	3.29e-03	55	29	2	1.10.30.10
Domain	C1	PRKCB KMT2C	4.56e-03	65	29	2	SM00109
Domain	PE/DAG-bd	PRKCB KMT2C	4.70e-03	66	29	2	IPR002219
Domain	PHD	KMT2C KMT2D	6.02e-03	75	29	2	PF00628
Domain	Znf_PHD-finger	KMT2C KMT2D	6.66e-03	79	29	2	IPR019787
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1	PRKCB KMT2C KMT2D CBX6 CBX8	2.68e-05	237	22	5	M27786
Pathway	REACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES	KMT2C KMT2D KAT14	3.64e-05	42	22	3	M48018
Pathway	REACTOME_VEGFR2_MEDIATED_CELL_PROLIFERATION	PRKCB PDPK2P	1.79e-04	13	22	2	MM15171
Pathway	WP_8Q1123_RB1CC1_COPY_NUMBER_VARIATION	GABARAP GABARAPL1	2.75e-04	16	22	2	M48107
Pathway	REACTOME_SIGNALING_BY_CYTOSOLIC_FGFR1_FUSION_MUTANTS	ZMYM2 CEP43	3.50e-04	18	22	2	M673
Pathway	BIOCARTA_EIF4_PATHWAY	PRKCB PDPK2P	5.77e-04	23	22	2	MM1470
Pathway	REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION	KMT2C SMARCA5 KMT2D KAT14	5.83e-04	254	22	4	M27131
Pathway	KEGG_MEDICUS_REFERENCE_DEUBIQUITINATION_OF_H2AK119	CBX6 CBX8	7.39e-04	26	22	2	M47923
Pathway	REACTOME_CHROMATIN_MODIFYING_ENZYMES	KMT2C KMT2D EP400 KAT14	7.54e-04	272	22	4	M29619
Pathway	REACTOME_FGFR1_MUTANT_RECEPTOR_ACTIVATION	ZMYM2 CEP43	1.05e-03	31	22	2	M661
Pathway	WP_MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY	ZMYM2 SMARCA5 KMT2D EP400	1.10e-03	301	22	4	MM15983
Pathway	REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION	SMARCA5 KMT2D KAT14	1.18e-03	136	22	3	MM14848
Pathway	REACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN	CBX6 CBX8	1.27e-03	34	22	2	MM15531
Pathway	KEGG_REGULATION_OF_AUTOPHAGY	GABARAP GABARAPL1	1.34e-03	35	22	2	M6382
Pathway	WP_2Q37_COPY_NUMBER_VARIATION_SYNDROME	GABARAP GABARAPL1 RPS6	1.42e-03	145	22	3	M45512
Pathway	REACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN	CBX6 CBX8	1.50e-03	37	22	2	M27797
Pathway	REACTOME_SIGNALING_BY_FGFR1_IN_DISEASE	ZMYM2 CEP43	1.58e-03	38	22	2	M27536
Pathway	REACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES	KMT2D KAT14	1.58e-03	38	22	2	MM17073
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1	KMT2D CBX6 CBX8	1.66e-03	153	22	3	MM15522
Pathway	KEGG_MEDICUS_REFERENCE_GENE_SILENCING_BY_METHYLATION_OF_H3K27_AND_UBIQUITINATION_OF_H2AK119	CBX6 CBX8	1.75e-03	40	22	2	M47917
Pubmed	Cloning, expression patterns, and chromosome localization of three human and two mouse homologues of GABA(A) receptor-associated protein.	GABARAP GABARAPL3 GABARAPL1	2.32e-09	4	30	3	11414770
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	ZMYM2 KMT2C SMARCA5 KMT2D EP400 RBM27 KAT14 RPL5 RPS6 CBX8	7.47e-08	1294	30	10	30804502
Pubmed	The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes.	SMARCA5 KMT2D EP400	1.65e-07	13	30	3	16510874
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	ZMYM2 TCEAL7 SMARCA5 EP400 RBM27 RPL5 VARS1 CBX8 NDUFS5	2.10e-07	1082	30	9	38697112
Pubmed	Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program.	SMARCA5 KMT2D EP400	2.62e-07	15	30	3	16510875
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	ZMYM2 KMT2C LIMCH1 GZF1 EP400 RBM27 VARS1 PI4KA CBX8 NDUFS5	2.89e-07	1497	30	10	31527615
Pubmed	An Oct4-centered protein interaction network in embryonic stem cells.	ZMYM2 KMT2C SMARCA5 KMT2D EP400	3.11e-07	167	30	5	20362541
Pubmed	Interaction network of human early embryonic transcription factors.	ZMYM2 KMT2C SMARCA5 KMT2D EP400 KAT14	4.90e-07	351	30	6	38297188
Pubmed	Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation.	KMT2C KMT2D	7.19e-07	2	30	2	28483418
Pubmed	Loss of MLL3/4 decouples enhancer H3K4 monomethylation, H3K27 acetylation, and gene activation during embryonic stem cell differentiation.	KMT2C KMT2D	7.19e-07	2	30	2	36869380
Pubmed	Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability.	KMT2C KMT2D	7.19e-07	2	30	2	28967912
Pubmed	The MLL3/4 H3K4 methyltransferase complex in establishing an active enhancer landscape.	KMT2C KMT2D	7.19e-07	2	30	2	34156443
Pubmed	Expression of gec1/GABARAPL1 versus GABARAP mRNAs in human: predominance of gec1/GABARAPL1 in the central nervous system.	GABARAP GABARAPL1	7.19e-07	2	30	2	14625090
Pubmed	Crucial roles of mixed-lineage leukemia 3 and 4 as epigenetic switches of the hepatic circadian clock controlling bile acid homeostasis in mice.	KMT2C KMT2D	7.19e-07	2	30	2	25346535
Pubmed	KMT2C/D COMPASS complex-associated diseases [KCDCOM-ADs]: an emerging class of congenital regulopathies.	KMT2C KMT2D	7.19e-07	2	30	2	31924266
Pubmed	Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma.	KMT2C KMT2D	7.19e-07	2	30	2	27280393
Pubmed	Association of KMT2C/D loss-of-function variants with response to immune checkpoint blockades in colorectal cancer.	KMT2C KMT2D	7.19e-07	2	30	2	36601880
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	ZMYM2 SMARCA5 EP400 RBM27 VARS1 CBX8	9.60e-07	394	30	6	27248496
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	SMARCA5 KMT2D NEB VARS1 RPS6	1.64e-06	234	30	5	36243803
Pubmed	Mutations of PTCH1, MLL2, and MLL3 are not frequent events in hepatoblastoma.	KMT2C KMT2D	2.16e-06	3	30	2	22183980
Pubmed	Direct binding to GABARAP family members is essential for HIV-1 Nef plasma membrane localization.	GABARAP GABARAPL1	2.16e-06	3	30	2	28729737
Pubmed	Effects of C-terminal modifications of GEC1 protein and gamma-aminobutyric acid type A (GABA(A)) receptor-associated protein (GABARAP), two microtubule-associated proteins, on kappa opioid receptor expression.	GABARAP GABARAPL1	2.16e-06	3	30	2	21388957
Pubmed	GABA(A)-receptor-associated protein links GABA(A) receptors and the cytoskeleton.	GABARAP GABARAPL1	2.16e-06	3	30	2	9892355
Pubmed	Lack of GABARAP-Type Proteins Is Accompanied by Altered Golgi Morphology and Surfaceome Composition.	GABARAP GABARAPL1	2.16e-06	3	30	2	33374830
Pubmed	Arginine68 is an essential residue for the C-terminal cleavage of human Atg8 family proteins.	GABARAP GABARAPL1	2.16e-06	3	30	2	23721406
Pubmed	METTL3 promotes hyperoxia-induced pyroptosis in neonatal bronchopulmonary dysplasia by inhibiting ATG8-mediated autophagy.	GABARAP GABARAPL1	2.16e-06	3	30	2	37478627
Pubmed	Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.	KMT2C KMT2D	2.16e-06	3	30	2	23932714
Pubmed	Starch binding domain-containing protein 1/genethonin 1 is a novel participant in glycogen metabolism.	GABARAP GABARAPL1	2.16e-06	3	30	2	20810658
Pubmed	HOXC6 Is transcriptionally regulated via coordination of MLL histone methylase and estrogen receptor in an estrogen environment.	KMT2C KMT2D	2.16e-06	3	30	2	21683083
Pubmed	Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes.	KMT2C SMARCA5 KMT2D DCLRE1C	3.33e-06	119	30	4	23508102
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	ZMYM2 KMT2C KMT2D CBX6 KAT14 CBX8	3.58e-06	495	30	6	27705803
Pubmed	Crucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation.	KMT2C KMT2D	4.31e-06	4	30	2	19221051
Pubmed	Cancer gene mutation frequencies for the U.S. population.	KMT2C KMT2D	4.31e-06	4	30	2	34645806
Pubmed	MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.	KMT2C KMT2D	4.31e-06	4	30	2	28398509
Pubmed	The MLL3/MLL4 branches of the COMPASS family function as major histone H3K4 monomethylases at enhancers.	KMT2C KMT2D	4.31e-06	4	30	2	24081332
Pubmed	Subunit specificity and interaction domain between GABA(A) receptor-associated protein (GABARAP) and GABA(A) receptors.	GABRG3 GABARAP	4.31e-06	4	30	2	11948245
Pubmed	PX-RICS mediates ER-to-Golgi transport of the N-cadherin/beta-catenin complex.	GABARAP GABARAPL1	4.31e-06	4	30	2	18451111
Pubmed	Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs.	GABARAP GABARAPL1	4.31e-06	4	30	2	30767700
Pubmed	A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.	KMT2C KMT2D	4.31e-06	4	30	2	23129768
Pubmed	MLL3/MLL4-Associated PAGR1 Regulates Adipogenesis by Controlling Induction of C/EBPβ and C/EBPδ.	KMT2C KMT2D	7.18e-06	5	30	2	32601106
Pubmed	Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF.	KMT2C KMT2D	7.18e-06	5	30	2	31127101
Pubmed	Ribosomal protein genes are overexpressed in colorectal cancer: isolation of a cDNA clone encoding the human S3 ribosomal protein.	RPL5 RPS6	7.18e-06	5	30	2	1712897
Pubmed	A PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complex.	KMT2C KMT2D	7.18e-06	5	30	2	26744420
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	ZMYM2 KMT2C SMARCA5 EP400	7.50e-06	146	30	4	23892456
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	KMT2C MESD NEB VARS1 PI4KA	7.77e-06	322	30	5	26514267
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	KCTD20 SP100 SMARCA5 RBM27 RPL5 RPS6 CBX8 BTBD10	8.19e-06	1257	30	8	36526897
Pubmed	ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.	ZMYM2 SMARCA5 EP400 CBX8	8.35e-06	150	30	4	28242625
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	SMARCA5 KMT2D EP400 CBX6	9.99e-06	157	30	4	30186101
Pubmed	Lipidation of the LC3/GABARAP family of autophagy proteins relies on a membrane-curvature-sensing domain in Atg3.	GABARAP GABARAPL1	1.08e-05	6	30	2	24747438
Pubmed	MAPK15/ERK8 stimulates autophagy by interacting with LC3 and GABARAP proteins.	GABARAP GABARAPL1	1.08e-05	6	30	2	22948227
Pubmed	Nix, a receptor protein for mitophagy in mammals.	GABARAP GABARAPL1	1.08e-05	6	30	2	20200478
Pubmed	p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy.	GABARAP GABARAPL1	1.08e-05	6	30	2	17580304
Pubmed	A DNM2 Centronuclear Myopathy Mutation Reveals a Link between Recycling Endosome Scission and Autophagy.	GABARAP GABARAPL1	1.08e-05	6	30	2	32315611
Pubmed	Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases.	KMT2C KMT2D	1.08e-05	6	30	2	17021013
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	GABARAP SMARCA5 LIMCH1 GABARAPL1 RPL5 VARS1 RPS6	1.30e-05	949	30	7	36574265
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	ZMYM2 SMARCA5 EP400 RBM27 RPL5 CBX8 NDUFS5	1.34e-05	954	30	7	36373674
Pubmed	Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B-positive structures.	GABARAP GABARAPL1	1.51e-05	7	30	2	24668264
Pubmed	A single synonymous mutation determines the phosphorylation and stability of the nascent protein.	RPL5 RPS6	1.51e-05	7	30	2	30252118
Pubmed	Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4.	KMT2C KMT2D	1.51e-05	7	30	2	30604749
Pubmed	An ALS-associated variant of the autophagy receptor SQSTM1/p62 reprograms binding selectivity toward the autophagy-related hATG8 proteins.	GABARAP GABARAPL1	1.51e-05	7	30	2	34929165
Pubmed	Clustered PHD domains in KMT2/MLL proteins are attracted by H3K4me3 and H3 acetylation-rich active promoters and enhancers.	KMT2C KMT2D	1.51e-05	7	30	2	36598580
Pubmed	ASCOM controls farnesoid X receptor transactivation through its associated histone H3 lysine 4 methyltransferase activity.	KMT2C KMT2D	1.51e-05	7	30	2	19556342
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	MESD EP400 RBM27 CEP43 PI4KA CBX8	1.62e-05	645	30	6	25281560
Pubmed	Proteomics analysis of Ring1B/Rnf2 interactors identifies a novel complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6 interacting corepressor.	SMARCA5 CBX6 CBX8	1.64e-05	57	30	3	17296600
Pubmed	H3.3K4M destabilizes enhancer H3K4 methyltransferases MLL3/MLL4 and impairs adipose tissue development.	KMT2C KMT2D	2.01e-05	8	30	2	30335158
Pubmed	Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.	KMT2C KMT2D	2.01e-05	8	30	2	23130995
Pubmed	Recognition and specificity determinants of the human cbx chromodomains.	CBX6 CBX8	2.01e-05	8	30	2	21047797
Pubmed	Autophagy receptor NDP52 regulates pathogen-containing autophagosome maturation.	GABARAP GABARAPL1	2.01e-05	8	30	2	25771791
Pubmed	The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.	KMT2C KMT2D	2.01e-05	8	30	2	22266653
Pubmed	DOR/Tp53inp2 and Tp53inp1 constitute a metazoan gene family encoding dual regulators of autophagy and transcription.	GABARAP GABARAPL1	2.01e-05	8	30	2	22470510
Pubmed	Mass spectrometry proteomics reveals a function for mammalian CALCOCO1 in MTOR-regulated selective autophagy.	GABARAP GABARAPL1	2.01e-05	8	30	2	31971854
Pubmed	Four enzymes cooperate to displace histone H1 during the first minute of hormonal gene activation.	KMT2C KMT2D	2.01e-05	8	30	2	21447625
Pubmed	TRIM32, but not its muscular dystrophy-associated mutant, positively regulates and is targeted to autophagic degradation by p62/SQSTM1.	GABARAP GABARAPL1	2.01e-05	8	30	2	31685529
Pubmed	Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense.	GABARAP GABARAPL1	2.01e-05	8	30	2	28604719
Pubmed	Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth.	GABARAP GABARAPL1	2.58e-05	9	30	2	21617041
Pubmed	Regulation of endoplasmic reticulum turnover by selective autophagy.	GABARAP GABARAPL1	2.58e-05	9	30	2	26040720
Pubmed	The E3 ubiquitin ligase NEDD4 enhances killing of membrane-perturbing intracellular bacteria by promoting autophagy.	GABARAP GABARAPL1	2.58e-05	9	30	2	29251248
Pubmed	Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.	KMT2C KMT2D	2.58e-05	9	30	2	22665483
Pubmed	Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins.	GABARAP GABARAPL1	2.58e-05	9	30	2	29867141
Pubmed	Different polycomb group CBX family proteins associate with distinct regions of chromatin using nonhomologous protein sequences.	CBX6 CBX8	2.58e-05	9	30	2	18927235
Pubmed	Genetic interaction mapping in mammalian cells using CRISPR interference.	KMT2D EP400 CBX8	2.92e-05	69	30	3	28481362
Pubmed	NCOA2 promotes lytic reactivation of Kaposi's sarcoma-associated herpesvirus by enhancing the expression of the master switch protein RTA.	CEP43 PI4KA RPS6	3.05e-05	70	30	3	31751430
Pubmed	Nix is a selective autophagy receptor for mitochondrial clearance.	GABARAP GABARAPL1	3.22e-05	10	30	2	20010802
Pubmed	HUWE1 E3 ligase promotes PINK1/PARKIN-independent mitophagy by regulating AMBRA1 activation via IKKα.	GABARAP GABARAPL1	3.22e-05	10	30	2	30217973
Pubmed	PDK1 regulates vascular remodeling and promotes epithelial-mesenchymal transition in cardiac development.	PDPK2P RPS6	3.22e-05	10	30	2	20457809
Pubmed	ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8.	GABARAP GABARAPL1	3.22e-05	10	30	2	28287329
Pubmed	A role for NBR1 in autophagosomal degradation of ubiquitinated substrates.	GABARAP GABARAPL1	3.22e-05	10	30	2	19250911
Pubmed	The IAP family member BRUCE regulates autophagosome-lysosome fusion.	GABARAP GABARAPL1	3.22e-05	10	30	2	29426817
Pubmed	SIP/CacyBP promotes autophagy by regulating levels of BRUCE/Apollon, which stimulates LC3-I degradation.	GABARAP GABARAPL1	3.22e-05	10	30	2	31213539
Pubmed	Mouse polycomb proteins bind differentially to methylated histone H3 and RNA and are enriched in facultative heterochromatin.	CBX6 CBX8	3.22e-05	10	30	2	16537902
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	ZMYM2 KMT2C KMT2D EP400 RBM27 RPL5 VARS1	3.40e-05	1103	30	7	34189442
Pubmed	A directed protein interaction network for investigating intracellular signal transduction.	KMT2C MESD TCEAL7 CEP43 RPL5 PI4KA BTBD10	3.83e-05	1124	30	7	21900206
Pubmed	ATG8 family proteins act as scaffolds for assembly of the ULK complex: sequence requirements for LC3-interacting region (LIR) motifs.	GABARAP GABARAPL1	3.94e-05	11	30	2	23043107
Pubmed	MLL3/MLL4 methyltransferase activities control early embryonic development and embryonic stem cell differentiation in a lineage-selective manner.	KMT2C KMT2D	3.94e-05	11	30	2	37012455
Pubmed	Methods for Studying Interactions Between Atg8/LC3/GABARAP and LIR-Containing Proteins.	GABARAP GABARAPL1	3.94e-05	11	30	2	28253953
Pubmed	The DNA methyltransferase DNMT3A contributes to autophagy long-term memory.	GABARAP GABARAPL1	3.94e-05	11	30	2	32876528
Pubmed	CUL3-KBTBD6/KBTBD7 ubiquitin ligase cooperates with GABARAP proteins to spatially restrict TIAM1-RAC1 signaling.	GABARAP GABARAPL1	3.94e-05	11	30	2	25684205
Pubmed	mTORC1/2 signaling is downregulated by amino acid-free culture of mouse preimplantation embryos and is only partially restored by amino acid readdition.	PDPK2P RPS6	3.94e-05	11	30	2	33052068
Pubmed	Mutual protection of ribosomal proteins L5 and L11 from degradation is essential for p53 activation upon ribosomal biogenesis stress.	RPL5 RPS6	3.94e-05	11	30	2	23169665
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	KCTD20 SMARCA5 RBM27 RPL5 CBX8 BTBD10	4.02e-05	759	30	6	35915203
Interaction	H3C14 interactions	PRKCB KMT2C SMARCA5 KMT2D CBX6 CBX8	9.95e-08	156	30	6	int:H3C14
Interaction	H3C1 interactions	ZMYM2 PRKCB KMT2C SMARCA5 KMT2D NEB CBX6 KAT14 RPL5 CBX8	4.03e-07	901	30	10	int:H3C1
Interaction	H2BC21 interactions	ZMYM2 PRKCB MESD SMARCA5 NEB EP400 CBX6 KAT14 CBX8	4.95e-07	696	30	9	int:H2BC21
Interaction	H2AC4 interactions	KMT2C SMARCA5 KMT2D EP400 RBM27 CBX6 VARS1 CBX8	5.38e-07	506	30	8	int:H2AC4
Interaction	MECP2 interactions	ZMYM2 SP100 TCEAL7 SMARCA5 EP400 RBM27 RPL5 VARS1 RPS6 CBX8 NDUFS5	1.22e-06	1287	30	11	int:MECP2
Interaction	ELF5 interactions	ZMYM2 KMT2C SMARCA5 KMT2D RPL5	2.37e-06	147	30	5	int:ELF5
Interaction	TP53INP1 interactions	GABARAP GABARAPL1 KAT14	5.17e-06	23	30	3	int:TP53INP1
Interaction	FOXL1 interactions	KMT2C SMARCA5 KMT2D VARS1 PI4KA	9.67e-06	196	30	5	int:FOXL1
Interaction	KLF3 interactions	ZMYM2 SMARCA5 KMT2D EP400 KAT14	2.01e-05	228	30	5	int:KLF3
Interaction	PRKAR1B interactions	PRKCB MESD DCLRE1C CEP43 CBX8	2.47e-05	238	30	5	int:PRKAR1B
Interaction	H2BC3 interactions	ZMYM2 PRKCB KMT2C SMARCA5 KMT2D EP400	2.54e-05	406	30	6	int:H2BC3
Interaction	GABRG3 interactions	GABRG3 GABARAP	3.20e-05	6	30	2	int:GABRG3
Interaction	RPS19 interactions	SP100 SMARCA5 GZF1 CBX6 RPL5 VARS1 RPS6	3.36e-05	639	30	7	int:RPS19
Interaction	CBX3 interactions	ZMYM2 SP100 SMARCA5 EP400 RBM27 CBX6 CBX8	3.60e-05	646	30	7	int:CBX3
Interaction	RESF1 interactions	ZMYM2 GABARAP GABARAPL1	3.78e-05	44	30	3	int:RESF1
Interaction	FNBP1 interactions	GABARAP SMARCA5 GABARAPL1 VARS1	4.10e-05	131	30	4	int:FNBP1
Interaction	HNF4A interactions	ZMYM2 KMT2C KMT2D EP400 KAT14	4.92e-05	275	30	5	int:HNF4A
Interaction	CTCF interactions	ZMYM2 SP100 CBX6 RPL5 VARS1 RPS6	5.17e-05	461	30	6	int:CTCF
Interaction	H1-10 interactions	SP100 MESD RPL5 RPS6 CBX8	5.36e-05	280	30	5	int:H1-10
Interaction	H4C16 interactions	PRKCB CBX6 KAT14 CBX8	7.32e-05	152	30	4	int:H4C16
Interaction	AR interactions	ZMYM2 KMT2C SMARCA5 KMT2D LIMCH1 EP400 RBM27 RPS6	7.44e-05	992	30	8	int:AR
Interaction	RCOR1 interactions	ZMYM2 SP100 SMARCA5 KMT2D KAT14 VARS1	7.58e-05	494	30	6	int:RCOR1
Interaction	H3-3A interactions	ZMYM2 KMT2C SMARCA5 KMT2D CBX6 VARS1 CBX8	9.18e-05	749	30	7	int:H3-3A
Interaction	MEN1 interactions	ZMYM2 KMT2C SMARCA5 KMT2D EP400 RPL5 RPS6 CBX8	9.62e-05	1029	30	8	int:MEN1
Interaction	TSR1 interactions	SMARCA5 RPL5 VARS1 RPS6 CBX8	1.04e-04	322	30	5	int:TSR1
Interaction	NCL interactions	MESD SMARCA5 GZF1 CBX6 RPL5 RPS6 CBX8	1.36e-04	798	30	7	int:NCL
Interaction	STK3 interactions	GABARAP GABARAPL1 NEB CEP43	1.44e-04	181	30	4	int:STK3
Interaction	WDR5 interactions	ZMYM2 KMT2C SMARCA5 KMT2D KAT14 RPL5 VARS1 CBX8	1.54e-04	1101	30	8	int:WDR5
Interaction	PPAN interactions	SMARCA5 GZF1 RPS6 CBX8	1.84e-04	193	30	4	int:PPAN
Interaction	SETD1B interactions	KMT2C KMT2D KAT14	1.87e-04	75	30	3	int:SETD1B
Interaction	KLF12 interactions	ZMYM2 GZF1 EP400 KAT14	1.88e-04	194	30	4	int:KLF12
Interaction	ATG4D interactions	GABARAP GABARAPL1	1.93e-04	14	30	2	int:ATG4D
Interaction	HDLBP interactions	SMARCA5 LIMCH1 GZF1 EP400 RBM27 VARS1 CBX8	2.09e-04	855	30	7	int:HDLBP
Interaction	RING1 interactions	KMT2C SMARCA5 CBX6 CBX8	2.15e-04	201	30	4	int:RING1
Interaction	KRR1 interactions	SMARCA5 GZF1 CBX6 RPS6 CBX8	2.22e-04	379	30	5	int:KRR1
Interaction	HNF1A interactions	KMT2C SMARCA5 KMT2D	2.26e-04	80	30	3	int:HNF1A
Interaction	YTHDC2 interactions	CBX6 RPL5 RPS6 CBX8	2.32e-04	205	30	4	int:YTHDC2
Interaction	ATG13 interactions	GABARAP GABARAPL1 RPL5 RPS6	2.45e-04	208	30	4	int:ATG13
Interaction	NUP43 interactions	ZMYM2 KMT2D EP400 RPL5 PI4KA CBX8	2.73e-04	625	30	6	int:NUP43
Interaction	PHC1 interactions	SP100 CBX6 CBX8	2.80e-04	86	30	3	int:PHC1
Interaction	C7orf50 interactions	SP100 CBX6 RPL5 RPS6	2.93e-04	218	30	4	int:C7orf50
Interaction	FBL interactions	PRKCB SP100 SMARCA5 RPL5 RPS6 CBX8	3.08e-04	639	30	6	int:FBL
Interaction	GATA4 interactions	ZMYM2 SP100 SMARCA5 EP400 RPS6	3.22e-04	411	30	5	int:GATA4
Interaction	DUXB interactions	ZMYM2 SMARCA5	3.23e-04	18	30	2	int:DUXB
Interaction	ERCC6 interactions	SMARCA5 CBX6 RPL5 RPS6	3.25e-04	224	30	4	int:ERCC6
Interaction	NFIX interactions	KMT2C KMT2D EP400 KAT14	3.41e-04	227	30	4	int:NFIX
Interaction	HCFC2 interactions	KMT2C KMT2D KAT14	3.42e-04	92	30	3	int:HCFC2
Interaction	FOXI1 interactions	KMT2C KMT2D VARS1	3.42e-04	92	30	3	int:FOXI1
Interaction	NUFIP2 interactions	GABARAP SP100 GABARAPL1 CBX6 RPL5	3.44e-04	417	30	5	int:NUFIP2
Interaction	RPS3A interactions	SMARCA5 CBX6 RPL5 VARS1 RPS6 CBX8	3.51e-04	655	30	6	int:RPS3A
Interaction	H1-4 interactions	PRKCB SP100 SMARCA5 NEB RPS6 CBX8	3.54e-04	656	30	6	int:H1-4
Interaction	RPS15 interactions	MESD NEB CBX6 RPL5 RPS6	3.68e-04	423	30	5	int:RPS15
Interaction	BUB3 interactions	KCTD20 KMT2C KMT2D BTBD10	3.71e-04	232	30	4	int:BUB3
Interaction	FOXG1 interactions	ZMYM2 SMARCA5 VARS1	3.76e-04	95	30	3	int:FOXG1
Interaction	H1-2 interactions	PRKCB SP100 LIMCH1 NEB EP400 CBX6	3.84e-04	666	30	6	int:H1-2
Interaction	SOX9 interactions	KMT2C KMT2D EP400	3.99e-04	97	30	3	int:SOX9
Interaction	DUSP16 interactions	KCTD20 GABARAP CEP43 BTBD10	4.02e-04	237	30	4	int:DUSP16
Interaction	MEFV interactions	GABARAP GABARAPL1	4.42e-04	21	30	2	int:MEFV
Interaction	NAA40 interactions	ZMYM2 SMARCA5 LIMCH1 EP400 RBM27 RPL5 RPS6	4.73e-04	978	30	7	int:NAA40
Interaction	RPL18A interactions	GZF1 RPL5 VARS1 RPS6 CBX8	4.73e-04	447	30	5	int:RPL18A
Interaction	GZF1 interactions	GZF1 CBX6 RPS6	4.76e-04	103	30	3	int:GZF1
Interaction	DNAAF4 interactions	GABARAP GABARAPL1	4.86e-04	22	30	2	int:DNAAF4
Interaction	C8A interactions	ZMYM2 MESD	4.86e-04	22	30	2	int:C8A
Interaction	NEPRO interactions	CBX6 RPL5 RPS6	4.90e-04	104	30	3	int:NEPRO
Interaction	YY1 interactions	ZMYM2 SP100 SMARCA5 EP400 KAT14	5.08e-04	454	30	5	int:YY1
Interaction	ZNF770 interactions	ZMYM2 GZF1 RPS6	5.18e-04	106	30	3	int:ZNF770
Interaction	MACROH2A1 interactions	ZMYM2 SP100 SMARCA5 VARS1 CBX8	5.29e-04	458	30	5	int:MACROH2A1
Interaction	ZNF7 interactions	CBX6 RPS6	5.32e-04	23	30	2	int:ZNF7
Interaction	UTY interactions	KMT2C KMT2D	5.32e-04	23	30	2	int:UTY
Interaction	H1-0 interactions	PRKCB SMARCA5 RPL5 CBX8	5.37e-04	256	30	4	int:H1-0
Interaction	SMC5 interactions	ZMYM2 SMARCA5 EP400 RBM27 RPL5 CBX8 NDUFS5	5.41e-04	1000	30	7	int:SMC5
Interaction	HMGB2 interactions	PRKCB SP100 NEB RPS6	5.53e-04	258	30	4	int:HMGB2
Interaction	EN1 interactions	KMT2C KMT2D EP400	5.77e-04	110	30	3	int:EN1
Interaction	LYN interactions	PRKCB CBX6 CEP43 RPL5 PI4KA RPS6	5.80e-04	720	30	6	int:LYN
Interaction	ESRRB interactions	KMT2C SMARCA5 KMT2D EP400	5.86e-04	262	30	4	int:ESRRB
Interaction	ASH2L interactions	KMT2C MESD KMT2D KAT14	6.12e-04	265	30	4	int:ASH2L
Interaction	SRPK1 interactions	GABARAP GABARAPL1 RBM27 RPL5 RPS6	6.36e-04	477	30	5	int:SRPK1
Interaction	ADARB1 interactions	SMARCA5 GZF1 RPL5 VARS1 RPS6	7.11e-04	489	30	5	int:ADARB1
Interaction	ETS1 interactions	SP100 KMT2D EP400	7.61e-04	121	30	3	int:ETS1
Interaction	CBX6 interactions	GZF1 CBX6 RPL5 CBX8	7.82e-04	283	30	4	int:CBX6
Interaction	BICC1 interactions	GABARAP GABARAPL1	7.90e-04	28	30	2	int:BICC1
Interaction	MTF1 interactions	SMARCA5 RPL5 RPS6	7.99e-04	123	30	3	int:MTF1
Interaction	ZNF629 interactions	ZMYM2 CBX6 RPS6	7.99e-04	123	30	3	int:ZNF629
Interaction	RPL36 interactions	GZF1 CBX6 RPL5 RPS6 CBX8	8.15e-04	504	30	5	int:RPL36
Interaction	RSF1 interactions	SP100 SMARCA5 RPS6	8.18e-04	124	30	3	int:RSF1
Interaction	RBBP5 interactions	KMT2C SMARCA5 KMT2D KAT14	8.24e-04	287	30	4	int:RBBP5
Interaction	RNF4 interactions	ZMYM2 SP100 SMARCA5 GZF1 RBM27 KAT14 RPL5 RPS6	8.28e-04	1412	30	8	int:RNF4
Interaction	RBBP7 interactions	ZMYM2 SMARCA5 EP400 RPL5 VARS1	8.37e-04	507	30	5	int:RBBP7
Interaction	ZNF827 interactions	SP100 MESD	8.48e-04	29	30	2	int:ZNF827
Interaction	TTBK1 interactions	GABARAP GABARAPL1	8.48e-04	29	30	2	int:TTBK1
Interaction	TMOD4 interactions	NEB KAT14	8.48e-04	29	30	2	int:TMOD4
Interaction	SOX2 interactions	ZMYM2 KMT2C SMARCA5 KMT2D EP400 RPL5 PI4KA RPS6	8.67e-04	1422	30	8	int:SOX2
Interaction	ACTB interactions	LIMCH1 NEB EP400 KAT14 PI4KA RPS6 NDUFS5	8.69e-04	1083	30	7	int:ACTB
Interaction	H2AJ interactions	PRKCB RBM27 CBX8	8.76e-04	127	30	3	int:H2AJ
Interaction	HARS1 interactions	RPL5 VARS1 PI4KA	8.76e-04	127	30	3	int:HARS1
Interaction	HCFC1 interactions	KMT2C KMT2D EP400 KAT14	8.90e-04	293	30	4	int:HCFC1
Interaction	SPATS2L interactions	CBX6 CEP43 RPS6	8.96e-04	128	30	3	int:SPATS2L
Interaction	ESCO1 interactions	CEP43 CBX8	9.08e-04	30	30	2	int:ESCO1
Interaction	ZNF286A interactions	CBX6 RPS6	9.08e-04	30	30	2	int:ZNF286A
Interaction	KMT2B interactions	KMT2C KMT2D KAT14	9.37e-04	130	30	3	int:KMT2B
Cytoband	Ensembl 112 genes in cytogenetic band chr20p11	GZF1 KAT14	4.51e-03	153	30	2	chr20p11
GeneFamily	Chromobox family	CBX6 CBX8	3.94e-05	8	22	2	976
GeneFamily	PHD finger proteins	KMT2C SP100 KMT2D	1.72e-04	90	22	3	88
GeneFamily	Ataxins\|Trinucleotide repeat containing	KMT2D EP400	4.17e-04	25	22	2	775
GeneFamily	Autophagy related	GABARAP GABARAPL1	7.29e-04	33	22	2	1022
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	KMT2C KMT2D	7.74e-04	34	22	2	487
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	SMARCA5 EP400	1.88e-03	53	22	2	532
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	GZF1 BTBD10	1.14e-02	134	22	2	861
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-B_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRKCB RPL5 VARS1 RPS6	8.24e-06	193	30	4	a808eb426b4ce9ddf7d6556b083abd9232a218b1
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-B_cell-B_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRKCB RPL5 VARS1 RPS6	8.24e-06	193	30	4	e1d0b2d2d6b65d32922e22d092848ac4200669d5
ToppCell	CV-Mild-0\|Mild / Virus stimulation, Condition and Cluster	GABARAP GABARAPL1 RPL5 RPS6	8.58e-06	195	30	4	2ffb9a9b6143bb404fe454cd939b573252bba6e9
ToppCell	normal_Pleural_Fluid\|World / Location, Cell class and cell subclass	PRKCB SP100 RPL5 RPS6	8.76e-06	196	30	4	7029c9f4a826f6cfdcb5f7a472fba94e8945a771
ToppCell	Striatum-Neuronal-Excitatory\|Striatum / BrainAtlas - Mouse McCarroll V32	PRKCB TCEAL7 GABARAPL1 PI4KA	8.76e-06	196	30	4	67400193ba469cf4d939e94f5ed94995e384bc07
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-B_lymphocytic-memory_B_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PRKCB SP100 RPL5 RPS6	8.94e-06	197	30	4	43e576bd6997915d21137e233e36984eba31f637
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature2_(2)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	GABRG3 PRKCB RPL5 RPS6	9.12e-06	198	30	4	df681a2308bf75f4d3cef05d7418aabc96116880
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PRKCB GABARAPL1 RPL5 RPS6	9.12e-06	198	30	4	1f8fc486e0cd77749b61a5b2481a1826f0bcf087
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature2_(2)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PRKCB RPL5 RPS6 NDUFS5	9.12e-06	198	30	4	a14d16d4755bd523d66e3b55e7d78cbb5359acfc
ToppCell	(02)_MMP9/10+-(2)_GFP_FOXI1\|(02)_MMP9/10+ / shred by cell type by condition	SP100 GABARAPL1 RBM27 RPS6	9.30e-06	199	30	4	18a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature2_(2)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	GABRG3 PRKCB RPL5 RPS6	9.30e-06	199	30	4	d946db0e8cc3fbed2d0eb9b4346400138d43219f
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	GABARAPL1 RPL5 RPS6 NDUFS5	9.49e-06	200	30	4	87d0240328d1c4f0aa052c2dc96155c884ee514b
ToppCell	Parenchymal-10x5prime\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	GABARAP RPL5 RPS6 NDUFS5	9.49e-06	200	30	4	4bb6e1129bdf62a90b7e6c9740459129b92e3c02
ToppCell	Tracheal-10x5prime\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	GABARAP RPL5 RPS6 NDUFS5	9.49e-06	200	30	4	26730c59457a17ba3221cb4372f1068feb0342a0
ToppCell	COVID-mono2\|COVID / Condition, Cell_class and T cell subcluster	GABARAP RPL5 RPS6	6.61e-05	117	30	3	118a8f62c9d02bb7bd8b020e8234b1b886299884
ToppCell	COVID-mono2-\|COVID / Condition, Cell_class and T cell subcluster	GABARAP RPL5 RPS6	6.61e-05	117	30	3	5fba87acbd63d00c689e10302542651fc2161a3e
ToppCell	Lymphoid-Lymphoid-T_cells_(Cd4+_Tnaive-Tcm)\|Lymphoid / shred on cell class and cell subclass (v4)	RPL5 RPS6 CBX8	1.46e-04	153	30	3	ffb8ac88513e83d3ba01574e60beb5476154372b
ToppCell	normal_Lung-Myeloid_cells-Pleural_Mac\|Myeloid_cells / Location, Cell class and cell subclass	CBX6 RPL5 RPS6	1.49e-04	154	30	3	835ef49d314ecbcbfd8d1041ba202a5eedcda0bd
ToppCell	Smart-seq2-thymus_(Smart-seq2)-lymphocytic-B_lymphocytic-memory_B_cell\|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SP100 RPL5 RPS6	1.55e-04	156	30	3	cea7b4f133272499e77ed451db91f699cff6a4bb
ToppCell	droplet-Fat-Scat-21m-Lymphocytic-B_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKCB VARS1 RPS6	1.70e-04	161	30	3	e52735f955f0a53da5cbe5a2d77a00484e5109b3
ToppCell	droplet-Lung-nan-18m-Lymphocytic-Zbtb32+_B\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKCB SP100 VARS1	1.86e-04	166	30	3	3e3e9296e6919a38602e417a6606c046af3bd101
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRKCB SP100 VARS1	1.93e-04	168	30	3	943687a33fffd7e19d906b9dd385a126bcea109a
ToppCell	LAM-Lymphoid-B-cell-1\|LAM / Condition, Lineage and Cell class	PRKCB RPL5 RPS6	2.00e-04	170	30	3	2b822a95a8d7ee193d40231418d6bd4cf9662842
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRKCB SP100 VARS1	2.03e-04	171	30	3	656a9f407461dbf5c9c0bd234399e1fef6abce2a
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRKCB SP100 VARS1	2.07e-04	172	30	3	3784fd1e833703519889942e39fda991f03c3c76
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRKCB SP100 VARS1	2.07e-04	172	30	3	995139aa38f8b9ff23166128b15476cd8a3ff1b8
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-Zbtb32+_B\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKCB SP100 VARS1	2.14e-04	174	30	3	28ec25767bbd4fd898738f9f4d2b585dc91b5adf
ToppCell	COVID-19_Convalescent\|World / Disease group, lineage and cell class	GABARAP RPL5 RPS6	2.17e-04	175	30	3	4d6343308ec5a644af1432ef0f63dcaf9f02e4bc
ToppCell	PBMC-Convalescent\|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GABARAP RPL5 RPS6	2.17e-04	175	30	3	4dc4d0d3bf887a52adbe9d81c8a03fc95bc7a4b0
ToppCell	PBMC-Convalescent\|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)	GABARAP RPL5 RPS6	2.17e-04	175	30	3	d3f897271b64872535213a3dc27b9330255ef9ee
ToppCell	droplet-Lung-nan-21m-Lymphocytic-Zbtb32+_B\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKCB SP100 VARS1	2.21e-04	176	30	3	741fdacb33d49b030a797a6099fdea0949a22e75
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRKCB SP100 VARS1	2.25e-04	177	30	3	c506b8fd9a550e6cf93b64a1f7eed2543224a140
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRKCB SP100 VARS1	2.25e-04	177	30	3	840eaac045ada42cae0ab81177d1d0ae55a65633
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRKCB SP100 VARS1	2.29e-04	178	30	3	8d74c12c4b0ce8bcb0f59151bdc67036997095ef
ToppCell	RSV-Healthy-4\|RSV / Virus stimulation, Condition and Cluster	ZMYM2 RPL5 RPS6	2.29e-04	178	30	3	a5835951492c051443f3c30d45f9a7b1b2557477
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRKCB SP100 VARS1	2.29e-04	178	30	3	8ef229f38aa8a2ae8b366c3ce26d4cb1302d674a
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRKCB SP100 VARS1	2.29e-04	178	30	3	525c4b3f9736ff206e2f1378c2a29ba4f13ba22f
ToppCell	RSV-Healthy-4\|Healthy / Virus stimulation, Condition and Cluster	ZMYM2 RPL5 RPS6	2.29e-04	178	30	3	a6d71aebb5c462311f8ade24f659642b6b329633
ToppCell	facs-BAT-Fat-24m-Lymphocytic-B_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKCB RPL5 RPS6	2.32e-04	179	30	3	932fc2bd62ff024068004825beda1ea493f2d650
ToppCell	droplet-Lung-nan-21m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKCB SP100 VARS1	2.36e-04	180	30	3	b673d11d764e275883fc5edbad97137a6549df6a
ToppCell	Severe-B_naive-12\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	GABARAP RPL5 RPS6	2.36e-04	180	30	3	bc20e581d37cba72b71ef62df60475a0ccee9994
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRKCB SP100 VARS1	2.36e-04	180	30	3	b83d067dee641941c596e4a25d81327931b6ad61
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKCB SP100 VARS1	2.40e-04	181	30	3	46de8c18e4ec8dc9d07f7c8cc7b5f48b9c613aae
ToppCell	COVID-19_Convalescent\|World / Disease condition and Cell class	GABARAP RPL5 RPS6	2.40e-04	181	30	3	a62115a8da486fc61225901c72b1ec70bcaf4c36
ToppCell	droplet-Spleen-nan-18m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SP100 SMARCA5 VARS1	2.44e-04	182	30	3	eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRKCB SP100 VARS1	2.48e-04	183	30	3	b9e14199abc13a4873a77d23be1a37b0d4599b0f
ToppCell	droplet-Spleen-nan-18m-Lymphocytic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SP100 SMARCA5 VARS1	2.48e-04	183	30	3	28cbf909424f3be4491d49832f0aca0386560814
ToppCell	droplet-Spleen-nan-18m-Lymphocytic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SP100 SMARCA5 VARS1	2.48e-04	183	30	3	3fa608aa6b119869ec3280dc388dfee57160e63a
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-Zbtb32+_B_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRKCB SP100 VARS1	2.56e-04	185	30	3	5fd4a3776259c96cf2dcb87f050af8226acbbda9
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRKCB SP100 VARS1	2.56e-04	185	30	3	4c55fa96877ab9a00fcbec3fb70fd2208d222527
ToppCell	droplet\|World / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABARAP RPL5 RPS6	2.60e-04	186	30	3	fd69a94144710d63fe047cdc50813f42ac7ab68d
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABARAPL1 RPL5 RPS6	2.60e-04	186	30	3	1cbb1a1c4f0f6078e9c7b4e0dc93d6b6de7e57db
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Lymphocytic-B_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKCB VARS1 RPS6	2.60e-04	186	30	3	0018a949f9f5bfc17f823601303f04dfd56c9a38
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-B_cell-B_cell-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PRKCB RPL5 RPS6	2.64e-04	187	30	3	4f79b36c07efd3d6a2fa7220269cabeec11157df
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-B_cell-B_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRKCB VARS1 RPS6	2.68e-04	188	30	3	9526d9e035eadbb0dcd4ad6e79a3a2b7f7845d74
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Striatum / BrainAtlas - Mouse McCarroll V32	PRKCB TCEAL7 GABARAPL1	2.68e-04	188	30	3	e34ea7014c5a059a7db38f78bd903cf02616ddd3
ToppCell	tumor_Lung-Myeloid_cells-CD141+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	CBX6 RPL5 RPS6	2.68e-04	188	30	3	9874ba56bf6a0d509cccc89563dbf1395e17e84e
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-B_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRKCB VARS1 RPS6	2.68e-04	188	30	3	7c542b226240adcb7797be0ded6523e5732f0078
ToppCell	droplet\|World / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABARAP RPL5 RPS6	2.72e-04	189	30	3	6e779e4f9fed7b95c4cc975b1054331d507449b2
ToppCell	facs-BAT-Fat-3m-Lymphocytic-nan\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKCB RPL5 RPS6	2.77e-04	190	30	3	c6709b6cb518c569d06fb234a0e3b0434ef08392
ToppCell	facs-BAT-Fat-3m-Lymphocytic\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKCB RPL5 RPS6	2.77e-04	190	30	3	8ce836bd45634b668a87e2b8d49ccaf1e43e003e
ToppCell	droplet\|World / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABARAP RPL5 RPS6	2.77e-04	190	30	3	57c607bfad64db05cbe3dec9fe1b8955fc4bc262
ToppCell	droplet\|World / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GABARAP RPL5 RPS6	2.77e-04	190	30	3	807b950db50ee6699da8e85e283e6f90ba532cbe
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RPL5 RPS6 NDUFS5	2.77e-04	190	30	3	0b08710ec4a31837ba0ed1869d9880aad62198f3
ToppCell	droplet-Lung-nan-21m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKCB VARS1 RPS6	2.77e-04	190	30	3	046de398870b6d483466f369813b100c22743301
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_prolif-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GABARAP RPL5 RPS6	2.77e-04	190	30	3	e2b27194d964442a542574962b7e825098135447
ToppCell	facs-Brain_Myeloid-Striatum_-18m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABARAP LIMCH1 RPS6	2.81e-04	191	30	3	e0c9f49d2e26ccbc88b4ceae9918922f4b7cfd4d
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SP100 RPL5 RPS6	2.81e-04	191	30	3	b374676ac90572d65895052d46469906e2b6fd93
ToppCell	facs-Brain_Myeloid-Striatum_-18m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABARAP LIMCH1 RPS6	2.81e-04	191	30	3	f4a425a0e7382d01b5a8201c2c186966bb47011b
ToppCell	facs-Brain_Myeloid-Striatum_-18m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABARAP LIMCH1 RPS6	2.81e-04	191	30	3	fe17533b970540ad3339722e13dbf4029b20a756
ToppCell	droplet-Lung-1m-Hematologic-lymphocytic-B_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRKCB VARS1 RPS6	2.81e-04	191	30	3	6729b71fb674aea770a4a3167ccfc07acbf9f302
ToppCell	ILEUM-inflamed-(2)_B_cell\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PRKCB RPL5 RPS6	2.81e-04	191	30	3	0aa913678456b7d525bd177588f2463f6ed76cd7
ToppCell	metastatic_Brain-B_lymphocytes-Follicular_B_cells\|metastatic_Brain / Location, Cell class and cell subclass	PRKCB RPL5 RPS6	2.81e-04	191	30	3	f400fce79aacf029e20b6dca59d3e17bb2375f28
ToppCell	tumor_Lymph_Node_/_Brain-B_lymphocytes-Follicular_B_cells\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	PRKCB RPL5 RPS6	2.81e-04	191	30	3	06edf2e9b50ea20060648d41fa42ee16086fdf42
ToppCell	droplet-Lung-1m-Hematologic-lymphocytic-B_cell-B_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRKCB VARS1 RPS6	2.81e-04	191	30	3	f9fed8dbc4e4e34e59d8c4154e4e3fb320b12257
ToppCell	facs-Brain_Myeloid-Striatum_-18m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABARAP LIMCH1 RPS6	2.81e-04	191	30	3	d031430687b876930e9f718da20679938fd05edc
ToppCell	ILEUM-non-inflamed-(2)_B_cell\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PRKCB RPL5 RPS6	2.81e-04	191	30	3	d4496994dd973eb6d0d8b9101a390af237e12fb2
ToppCell	facs-Brain_Myeloid-Striatum_\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABARAP LIMCH1 RPS6	2.81e-04	191	30	3	de3b696de29a4b10c0870dec1792c7be9651d31e
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Lymphocytic\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKCB RPL5 RPS6	2.85e-04	192	30	3	0d96b24e5cadef45f0a7e380cd0415e80eca2e82
ToppCell	ILEUM-inflamed-(2)_Memory_B_cells\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PRKCB RPL5 RPS6	2.85e-04	192	30	3	4f82913e9ae8ab6dd3e8885a0a7f4dca92e318e1
ToppCell	Severe-B_naive-12\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	GABARAP RPL5 RPS6	2.85e-04	192	30	3	c482240645220d1753d76c0aa3a8ca14edb94a75
ToppCell	droplet-Lung-21m-Hematologic\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRKCB RPL5 RPS6	2.85e-04	192	30	3	3404d5feaad15bb1b040e8c146b6e88f1cc43eb9
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Lymphocytic-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKCB RPL5 RPS6	2.85e-04	192	30	3	757cc9d9e1a7b1e133c27aa9edccadfedf2a55d3
ToppCell	tumor_Lung-B_lymphocytes-Follicular_B_cells\|tumor_Lung / Location, Cell class and cell subclass	PRKCB RPL5 RPS6	2.90e-04	193	30	3	d0cb4bfc11491c903cb4cc0f823dd1ee239cf5c4
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	GABRG3 PRKCB LIMCH1	2.90e-04	193	30	3	9f69edc97b868d23998abc98928a2e89a885ef8a
ToppCell	facs-Thymus-nan-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKCB KMT2C DCLRE1C	2.90e-04	193	30	3	a6a864644e1b80b7417ea0a27281e79068a3fd3d
ToppCell	droplet-Mammary_Gland-nan-3m-Lymphocytic\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKCB RPL5 RPS6	2.90e-04	193	30	3	11bb0c1e506f7f46c2bcbe864867070fb1ce9030
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	GABRG3 PRKCB RPS6	2.90e-04	193	30	3	e2b455387d1de7812305200a2041a0f4759a6f54
ToppCell	LA-05._Cytoplasmic_Cardiomyocyte_I\|LA / Chamber and Cluster_Paper	RPL5 RPS6 NDUFS5	2.94e-04	194	30	3	e4b3a896e79666a935171af05c8d0b68de4fee32
ToppCell	PBMC-Mild\|PBMC / Compartment, Disease Groups and Clusters	KMT2C SP100 CBX6	2.94e-04	194	30	3	d1366b169d14011194e61d16b6b0953349febc78
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SP100 RPL5 RPS6	2.94e-04	194	30	3	9588a9b4baebbae08e13d201d4b9dfcf0e6521fb
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GABRG3 PRKCB LIMCH1	2.94e-04	194	30	3	35f132cc38ac133be01834ed0946188aa0757eb4
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-B_cell-B_cell-Z\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PRKCB RPL5 RPS6	2.94e-04	194	30	3	7820c15ab987695a338462adb96a411df975b85b
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-B_cell-B_cell\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PRKCB RPL5 RPS6	2.94e-04	194	30	3	397619f3917a25fe4ae6772992ee7a3d8ad862e0
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PRKCB RPL5 RPS6	2.94e-04	194	30	3	28c5482da199bcee9e85258a88af453d9fdbd56a
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-B_cell\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PRKCB RPL5 RPS6	2.94e-04	194	30	3	16eb26f4d1ac5ee6da74ebbce9fc2c0d54e9a693
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRKCB RPL5 RPS6	2.94e-04	194	30	3	dcf1b66f20ee9fe86de71221a086742140aa07d8
ToppCell	356C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	RPL5 RPS6 NDUFS5	2.94e-04	194	30	3	01eab9f799a0bf4af1f2bffedaa1d926d98abe0f
ToppCell	356C-Lymphocytic-CD4_T-cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	RPL5 RPS6 NDUFS5	2.94e-04	194	30	3	f51760caee571307851c78897789f6e43bac44ae
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells-Memory_B\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRKCB RPL5 RPS6	2.99e-04	195	30	3	f43dacc972dc4df574c4639952d3be9fc4201d33
Disease	Kleefstra syndrome 2 (implicated_via_orthology)	KMT2C KMT2D	9.99e-07	2	30	2	DOID:0080598 (implicated_via_orthology)
Disease	Sezary Syndrome	KMT2C KMT2D	3.45e-04	27	30	2	C0036920
Disease	lung non-small cell carcinoma (is_implicated_in)	PRKCB KMT2C KMT2D	3.78e-04	139	30	3	DOID:3908 (is_implicated_in)
Disease	glioblastoma (is_marker_for)	CBX6 CBX8	9.21e-04	44	30	2	DOID:3068 (is_marker_for)
Disease	esophagus squamous cell carcinoma (is_implicated_in)	KMT2C KMT2D	9.63e-04	45	30	2	DOID:3748 (is_implicated_in)
Disease	cognitive behavioural therapy	NEB DCLRE1C	1.59e-03	58	30	2	EFO_0007820
Disease	congenital heart disease (implicated_via_orthology)	KMT2C KMT2D	2.25e-03	69	30	2	DOID:1682 (implicated_via_orthology)
Disease	esophagus squamous cell carcinoma (is_marker_for)	KMT2D CBX8	2.58e-03	74	30	2	DOID:3748 (is_marker_for)
Disease	Hereditary Diffuse Gastric Cancer	PRKCB KMT2C RPS6	3.23e-03	293	30	3	C1708349
Disease	Stomach Neoplasms	PRKCB KMT2C RPS6	3.35e-03	297	30	3	C0038356
Disease	Malignant neoplasm of stomach	PRKCB KMT2C RPS6	3.45e-03	300	30	3	C0024623
Disease	Squamous cell carcinoma of esophagus	KMT2C KMT2D	4.21e-03	95	30	2	C0279626
Disease	lung disease severity measurement	GABRG3 PRKCB	6.41e-03	118	30	2	EFO_0007744
Disease	primary biliary cirrhosis	PRKCB CEP43	8.08e-03	133	30	2	EFO_1001486

Protein segments in the cluster

Peptide	Gene	Start	Entry
PEAKLPPVYVRKERK	EP400	2276	Q96L91
TYKEKVKKRPGGRPE	BTBD10	376	Q9BSF8
ERERELYGPKKRGPK	CBX6	61	O95503
DKKKEVVKPPYPKIR	GZF1	206	Q9H116
PAEEERDGRKKKYPS	RBM27	106	Q9P2N5
GTDGVKKRKRKPYRP	KMT2C	1266	Q8NEZ4
IEGYPTCKEKIKRRP	KCTD20	321	Q7Z5Y7
PPPRKKKKDIRDYND	MESD	46	Q14696
KPQLEKDTKPKEPRY	KAT14	446	Q9H8E8
AIIKPYPKGDERKKA	PI4KA	1746	P42356
SEGEKIRKKYPDRVP	GABARAP	16	O95166
EKLERKEIQPPYKPK	PRKCB	606	P05771
KEIQPPYKPKARDKR	PRKCB	611	P05771
QPRKKRPEDFKFGKI	PDPK2P	46	Q6A1A2
EREMELYGPKKRGPK	CBX8	61	Q9HC52
EPKYKPLGKLKRART	DCLRE1C	366	Q96SD1
PKPEKTYGLRKEPRK	CEP43	261	O95684
REYDKKLRPDIGIKP	GABRG3	56	Q99928
KEGEKIRKKYPDRVP	GABARAPL1	16	Q9H0R8
KEGEKIRKKYPDRVP	GABARAPL3	16	Q9BY60
PAPLRKKKAEREEYR	LIMCH1	281	Q9UPQ0
KPEKREKRDPGVITY	VARS1	266	P26640
YVVRKPLNKEGKKPR	RPS6	156	P62753
KQRDKLIKEGKYTPP	NDUFS5	81	O43920
AIRENPVYEKKPKKE	RPL5	246	P46777
KPKCSVPKREEKRPY	TCEAL7	11	Q9BRU2
EREMKTYIPPKGEKK	SP100	746	P23497
EEYEEQPRPRSKKKG	ZMYM2	1031	Q9UBW7
EKSLPPKKEVKIYVG	SMARCA5	401	O60264
TEESKKRKRKPYRPG	KMT2D	1681	O14686
KKKGYDLRPDAIPIK	NEB	2036	P20929