Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionubiquitin protein ligase activity

TRIM55 TRIM49 MYCBP2 TRIM49B HERC5 TRIM49C

8.54e-06372276GO:0061630
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

TRIM55 TRIM49 MYCBP2 TRIM49B HERC5 TRIM49C

1.25e-05398276GO:0061659
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

TRIM55 TRIM49 MYCBP2 TRIM49B HERC5 TRIM49C

3.32e-05473276GO:0004842
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

TRIM55 TRIM49 MYCBP2 TRIM49B HERC5 TRIM49C

5.16e-05512276GO:0019787
GeneOntologyMolecularFunctionacyltransferase activity

TRIM55 TRIM49 MYCBP2 TRIM49B BAZ1A HERC5 TRIM49C

5.81e-05775277GO:0016746
GeneOntologyMolecularFunctionaminoacyltransferase activity

TRIM55 TRIM49 MYCBP2 TRIM49B HERC5 TRIM49C

6.39e-05532276GO:0016755
GeneOntologyMolecularFunctiontransition metal ion binding

BLM TRIM55 TRIM49 EPRS1 DPYD MYCBP2 TRIM49B TRIM49C

1.24e-041189278GO:0046914
GeneOntologyMolecularFunctionzinc ion binding

BLM TRIM55 TRIM49 EPRS1 MYCBP2 TRIM49B TRIM49C

1.39e-04891277GO:0008270
GeneOntologyMolecularFunctionGTPase binding

ROCK2 EPRS1 DENND5A MYCBP2

1.31e-03360274GO:0051020
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

RALGDS DENND5A MYCBP2

3.64e-03231273GO:0005085
GeneOntologyMolecularFunctionGTPase regulator activity

RALGDS DENND5A MYCBP2 RALGAPB

4.53e-03507274GO:0030695
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

RALGDS DENND5A MYCBP2 RALGAPB

4.53e-03507274GO:0060589
GeneOntologyMolecularFunctionsmall GTPase binding

ROCK2 DENND5A MYCBP2

9.05e-03321273GO:0031267
GeneOntologyMolecularFunctionenzyme regulator activity

ROCK2 RALGDS DENND5A MYCBP2 RALGAPB DBNL

1.03e-021418276GO:0030234
GeneOntologyBiologicalProcessreplication-born double-strand break repair via sister chromatid exchange

BLM NIPBL

4.26e-058262GO:1990414
GeneOntologyBiologicalProcesscellular response to testosterone stimulus

ROCK2 SPP1

1.18e-0413262GO:0071394
GeneOntologyBiologicalProcessnegative regulation of thymocyte apoptotic process

BLM KIFAP3

1.18e-0413262GO:0070244
DomainZF_BBOX

TRIM55 TRIM49 MYCBP2 TRIM49B TRIM49C

9.52e-0880275PS50119
DomainZnf_B-box

TRIM55 TRIM49 MYCBP2 TRIM49B TRIM49C

1.01e-0781275IPR000315
DomainBBOX

TRIM55 TRIM49 TRIM49B TRIM49C

2.81e-0669274SM00336
Domain-

TRIM55 TRIM49 TRIM49B TRIM49C

3.15e-06712744.10.45.10
Domainzf-B_box

TRIM55 TRIM49 TRIM49B TRIM49C

3.33e-0672274PF00643
DomainRING

TRIM55 TRIM49 MYCBP2 TRIM49B BAZ1A TRIM49C

4.00e-06305276SM00184
DomainZnf_RING

TRIM55 TRIM49 MYCBP2 TRIM49B BAZ1A TRIM49C

5.87e-06326276IPR001841
Domain-

TRIM55 TRIM49 MYCBP2 TRIM49B BAZ1A TRIM49C

3.60e-054492763.30.40.10
DomainZnf_RING/FYVE/PHD

TRIM55 TRIM49 MYCBP2 TRIM49B BAZ1A TRIM49C

4.07e-05459276IPR013083
DomainZF_RING_1

TRIM55 TRIM49 MYCBP2 TRIM49B TRIM49C

5.41e-05291275PS00518
DomainZF_RING_2

TRIM55 TRIM49 MYCBP2 TRIM49B TRIM49C

6.05e-05298275PS50089
DomainButyrophylin

TRIM49 TRIM49B TRIM49C

1.38e-0470273IPR003879
DomainSPRY

TRIM49 TRIM49B TRIM49C

2.63e-0487273SM00449
DomainSPRY

TRIM49 TRIM49B TRIM49C

3.31e-0494273PF00622
DomainSPRY_dom

TRIM49 TRIM49B TRIM49C

3.31e-0494273IPR003877
DomainB30.2/SPRY

TRIM49 TRIM49B TRIM49C

3.41e-0495273IPR001870
DomainB302_SPRY

TRIM49 TRIM49B TRIM49C

3.41e-0495273PS50188
DomainRCC1

MYCBP2 HERC5

3.76e-0420272PF00415
DomainRCC1_3

MYCBP2 HERC5

4.16e-0421272PS50012
DomainRCC1_1

MYCBP2 HERC5

4.16e-0421272PS00625
DomainRCC1_2

MYCBP2 HERC5

4.16e-0421272PS00626
DomainReg_chr_condens

MYCBP2 HERC5

4.57e-0422272IPR000408
Domain-

MYCBP2 HERC5

4.57e-04222722.130.10.30
DomainRCC1/BLIP-II

MYCBP2 HERC5

5.00e-0423272IPR009091
DomainConA-like_dom

TRIM49 TRIM49B TRIM49C

3.78e-03219273IPR013320
Pubmed

Trim43a, Trim43b, and Trim43c: Novel mouse genes expressed specifically in mouse preimplantation embryos.

TRIM49 TRIM49B TRIM49C

1.89e-071527319703589
Pubmed

Identification of a genomic reservoir for new TRIM genes in primate genomes.

TRIM49 TRIM49B TRIM49C

4.01e-071927322144910
Pubmed

Osteopontin is An Important Regulative Component of the Fetal Bone Marrow Hematopoietic Stem Cell Niche.

SPP1 F10

1.74e-06327231461896
Pubmed

Ubiquitin-dependent recruitment of the Bloom syndrome helicase upon replication stress is required to suppress homologous recombination.

BLM TRIM49

3.48e-06427223708797
Pubmed

Lineage-specific biology revealed by a finished genome assembly of the mouse.

TRIM49 TRIM49B TRIM49C

1.07e-055527319468303
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

BLM ROCK2 EPRS1 MYCBP2 NIPBL RALGAPB

2.37e-0577427615302935
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

BLM ROCK2 EPRS1 NIPBL DBNL

3.85e-0550327516964243
Pubmed

Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.

TRIM55 MYCBP2 HERC5

5.51e-059527329643511
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

PPIL4 BLM EPRS1 MYCBP2 BAZ1A NIPBL DBNL

5.94e-05135327729467282
Pubmed

Functional screening of FxxLF-like peptide motifs identifies SMARCD1/BAF60a as an androgen receptor cofactor that modulates TMPRSS2 expression.

KIFAP3 DENND5A

6.06e-051527219762545
Pubmed

TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition.

TRIM55 TRIM49

1.09e-042027225127057
Pubmed

Identification of novel ARF binding proteins by two-hybrid screening.

PEX19 SPP1

1.21e-042127216582619
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

BLM EPRS1 HSPA4L BAZ1A

2.32e-0439427427248496
Pubmed

Proteome analysis of the HIV-1 Gag interactome.

EPRS1 HERC5

5.38e-044427225010285
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

BLM EPRS1 HSPA4L GTF3C6

5.45e-0449427426831064
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

BLM DPYD GC HSPA4L

5.57e-0449727436774506
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

ROCK2 INPP5F HSPA4L DBNL

5.61e-0449827436634849
Pubmed

New insights on the functional role of URG7 in the cellular response to ER stress.

ROCK2 EPRS1

6.14e-044727229704455
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

PPIL4 EPRS1 HSPA4L BAZ1A NIPBL DBNL

6.60e-04142527630948266
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

PPIL4 BLM NIPBL

6.70e-0422227337071664
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

EPRS1 BAZ1A NIPBL HERC5 DBNL

6.82e-0493427533916271
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

ROCK2 EPRS1 HSPA4L BAZ1A NIPBL DBNL

7.03e-04144227635575683
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

PPIL4 BLM EPRS1 BAZ1A NIPBL

7.51e-0495427536373674
Cytoband4q22.1

SPP1 HERC5

1.07e-04262724q22.1
CytobandEnsembl 112 genes in cytogenetic band chr4q22

SPP1 HERC5

8.76e-0474272chr4q22
CytobandEnsembl 112 genes in cytogenetic band chr11q14

TRIM49 TRIM49C

3.81e-03156272chr11q14
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM55 TRIM49 TRIM49B TRIM49C

1.24e-069516459
GeneFamilyRing finger proteins

TRIM55 TRIM49 TRIM49B TRIM49C

8.25e-0527516458
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

BLM ROCK2 KIFAP3 DPYD DENND5A INPP5F MYCBP2 BAZ1A NIPBL

1.12e-07856279M4500
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

PPIL4 BLM EPRS1 MYCBP2 SPP1 HSPA4L BAZ1A NIPBL

2.15e-07656278M18979
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

BLM ROCK2 DPYD DENND5A INPP5F MYCBP2 BAZ1A

3.50e-07466277M13522
CoexpressionGSE37534_UNTREATED_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP

PEX19 DPYD KIAA1549L CLBA1

4.74e-05197274M8980
CoexpressionGSE3982_CTRL_VS_LPS_4H_MAC_DN

ROCK2 DENND5A BAZ1A HERC5

4.93e-05199274M5368
CoexpressionBURTON_ADIPOGENESIS_9

ROCK2 KIFAP3 SPP1

9.10e-0585273M1666
CoexpressionBURTON_ADIPOGENESIS_9

ROCK2 KIFAP3 SPP1

1.04e-0489273MM1026
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_500_k-means-cluster#4

KIAA1549L HSPA4L BAZ1A NIPBL

4.22e-0698244Facebase_RNAseq_e10.5_Olfactory Pit_500_K4
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3

ROCK2 KIAA1549L BAZ1A NIPBL

5.97e-05192244Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000

BLM ROCK2 EPRS1 KIAA1549L HSPA4L BAZ1A NIPBL

8.02e-05989247Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500

ROCK2 KIAA1549L HSPA4L BAZ1A NIPBL

2.04e-04498245Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYCBP2 SPP1 BAZ1A F10

2.87e-061652741dcd6b8aa192baeaa1f7bb334843edab6049b96f
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYCBP2 SPP1 BAZ1A F10

3.46e-06173274279efbab7810fa60ab12ea5d09a84800df4adef0
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYCBP2 SPP1 BAZ1A F10

3.70e-061762746548797336c9f4ca0f38e74a2c629e2a4defa252
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RALGDS SPP1 BAZ1A F10

4.41e-06184274fe9ea4d0e0be820e95eaf9bb42a5560d0e177574
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RALGDS SPP1 BAZ1A F10

4.61e-061862747950e03ea080238c168b9d807e217f459acdfb28
ToppCell(04)_Interm._basal>secr.-(2)_GFP_FOXI1|(04)_Interm._basal>secr. / shred by cell type by condition

ROCK2 BAZ1A NIPBL GTF3C6

6.02e-0619927453ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCelldroplet-Liver-nan-3m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYD GC F10

1.02e-04151273b4a0546c1573b4b2290890307f2a5daf3a7cbb37
ToppCelldroplet-Liver-nan-3m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYD GC F10

1.02e-041512737758cfbe8dca849c90bd6e8bc63310e53beeb8fd
ToppCelldroplet-Liver-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYD GC F10

1.04e-041522731febeeb7376e34b9f86c81b2cb1314ee12408864
ToppCelldroplet-Liver-nan-3m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYD GC F10

1.04e-04152273faa92f7c5a6db9f1eb7d8ec930ba7c8ed9fd1bf1
ToppCellMyeloid-F|World / shred on cell class and cell subclass (v4)

RALGDS SPP1 F10

1.08e-041542736d53eec4aefe54836bbfd314f28f5e9a24c2d833
ToppCellMyeloid-Myeloid-F|Myeloid / shred on cell class and cell subclass (v4)

RALGDS SPP1 F10

1.13e-04156273d6317843ae5c5749452889e768c187a9d9e8c7fe
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYCBP2 SPP1 BAZ1A

1.26e-04162273d712bc31840ad1523e3dbf884acbb428a8995001
ToppCelldroplet-Liver-Hepatocytes|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYD GC F10

1.28e-04163273a794540f2d8984f963c08f05175e4bc916fcc224
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GC KIAA1549L F10

1.35e-04166273afba41e15478053f11815acf568d29187de75492
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYCBP2 SPP1 BAZ1A

1.48e-04171273845f312f8cbe29d820da25f0e6d75deb382bbfd8
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPP1 BAZ1A F10

1.50e-04172273584af6537685cb459bf0fc298e6f46872016c116
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_TH|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BLM SPP1 TRIM49B

1.58e-0417527302c67a10cbe849fbf38f082f42517e42483e8cb7
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

MYCBP2 HSPA4L BAZ1A

1.58e-041752730cc215109d9915af47e4d0a120ce2e46910715fa
ToppCelldroplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPP1 BAZ1A F10

1.61e-04176273e74ad0db3b05897edcfabeb11008ede2b9eeb638
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPP1 BAZ1A F10

1.61e-04176273b0b87eebcf5c994386b39ca607e17f10e9d9de74
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPP1 BAZ1A F10

1.63e-0417727367cc3a6461db5e0678f96b18224aeb83ad34b0f4
ToppCelldroplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPP1 BAZ1A F10

1.63e-0417727371919b5c9bfa87fdd2cd44dfa057b66ea081be5d
ToppCellLPS-antiTNF|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPYD SPP1 DBNL

1.66e-04178273289d1425c4e57fabcca994b27f9af1c0ce5d5bec
ToppCellfacs-Heart-RA-18m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROCK2 MYCBP2 DBNL

1.66e-04178273b505e2550860e777535ee95f29c936242fd607f1
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_TH|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BLM SPP1 TRIM49B

1.69e-04179273797d165718dd1d819e65add3a7859f87b32238a5
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPP1 BAZ1A F10

1.72e-04180273cc31d2cd06161300b91b17a67bb432b75f0d719b
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPP1 BAZ1A F10

1.77e-0418227321dcab170ffeef89faa9fee5008568cb6e15c694
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROCK2 MYCBP2 NIPBL

1.77e-04182273f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPP1 BAZ1A F10

1.77e-0418227394d061b7b5ebbfc564c644bc8b2d52341927145d
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROCK2 MYCBP2 NIPBL

1.83e-041842731154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DENND5A BAZ1A HERC5

1.86e-04185273f30fb9d75cdb757b206312992aaf7485bc900f96
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROCK2 MYCBP2 NIPBL

1.86e-041852737adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCellMyeloid-B_(Activated_Macrophage)|World / shred on cell class and cell subclass (v4)

RALGDS SPP1 BAZ1A

1.89e-0418627333d731a7883d75e4e7db83b641cdb1e9a39938bf
ToppCelldroplet-Bladder-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCBP2 BAZ1A NIPBL

1.92e-04187273663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Lymphocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

EPRS1 MYCBP2 HERC5

2.01e-04190273373629dde5eda722424c5e6087763f0c5db67cf4
ToppCellCD8+_Memory_T_cell-CV|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

RALGDS DPYD GTF3C6

2.27e-041982733d1749f5106f0912f4a74615863853949f52c73d
ToppCellSevere_COVID-19|World / Disease group,lineage and cell class （2021.01.30）

SPP1 BAZ1A HERC5

2.27e-0419827309fd456077bb3a657ad3b10c6cfe799b7266456a
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROCK2 KIFAP3 KIAA1549L

2.27e-041982738ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellBAL-Severe|BAL / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPP1 BAZ1A HERC5

2.27e-04198273454aee3f4fe6d0beeccc55200b4495f4f9b44feb
ToppCellBAL-Severe|BAL / Compartment, Disease Groups and Clusters

SPP1 BAZ1A HERC5

2.27e-04198273f63cfcc57f46094ea0673bbc70ea443ebaca6176
ToppCellBAL-Severe|BAL / Location, Disease Group, Cell group, Cell class (2021.03.09)

SPP1 BAZ1A HERC5

2.27e-04198273687f69c16343227854c882b4a0f3930ce534a3d2
ToppCellCV|World / Virus stimulation, Condition and Cluster

RALGDS DPYD GTF3C6

2.27e-041982736a28193af35abec5c029129930c2ca6febaafde2
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

MYCBP2 BAZ1A NIPBL

2.27e-0419827376d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCellSevere|World / Condition, Lineage, Cell class and cell subclass

SPP1 BAZ1A HERC5

2.31e-04199273a8b87f4f504a3b0ad6013277f0c9f543db3ef1fb
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

BAZ1A NIPBL GTF3C6

2.31e-0419927361b1ed2db71b96157b92b7535d1955a4033098da
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

BAZ1A NIPBL GTF3C6

2.31e-04199273fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCellSevere|World / Disease group and Cell class

BLM SPP1 GTF3C6

2.31e-04199273b73ae402b258fcc17e6cd6d6045244eccfe38ef8
ToppCell(00)_Basal-(2)_GFP_FOXI1|(00)_Basal / shred by cell type by condition

ROCK2 NIPBL GTF3C6

2.31e-0419927319674e1eaeb51e4196d847cb62aa437c852951d3
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

KIFAP3 KIAA1549L MYCBP2

2.34e-0420027348d801219bc771d6c7e151dc88ca4c179988de85
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-TH--L5-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

BLM SPP1 TRIM49B

2.34e-04200273e9b5105fff7845a98f962d609c2055528583b48e
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-KLHDC8A-|Neuronal / cells hierarchy compared to all cells using T-Statistic

BLM SPP1 TRIM49B

2.34e-042002731a04331862079092bc04b1010aa9228c0fa3d8c5
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MYCBP2 NIPBL HERC5

2.34e-0420027312f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-KLHDC8A--L5-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

BLM SPP1 TRIM49B

2.34e-04200273fb56d430957e73fba17db7bc0127ecf3577e0867
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-KLHDC8A|Neuronal / cells hierarchy compared to all cells using T-Statistic

BLM SPP1 TRIM49B

2.34e-0420027305bcde6ce8f1354ef65e4eb9cbd963a92108081c
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-TH-|Neuronal / cells hierarchy compared to all cells using T-Statistic

BLM SPP1 TRIM49B

2.34e-04200273fa0d4a0c93b0b0ad0331e7b7013373be27958c4e
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-TH|Neuronal / cells hierarchy compared to all cells using T-Statistic

BLM SPP1 TRIM49B

2.34e-042002733ece392f336547aea7dea625d9102819b04b4f7a
ToppCellCOVID-19|World / Disease, condition lineage and cell class

MYCBP2 NIPBL HERC5

2.34e-042002737dec470c379cd89f05a0f37c8628b21f136e52f0
DrugFenspiride hydrochloride [5053-08-7]; Down 200; 13.4uM; HL60; HG-U133A

KIFAP3 SPP1 HSPA4L NIPBL HERC5

2.55e-061962651422_DN
DiseaseLeukoencephalopathy

DPYD SPP1

4.41e-0511272C0270612
DiseaseChildhood Ataxia with Central Nervous System Hypomyelinization

DPYD SPP1

7.29e-0514272C1858991
DiseaseLung Neoplasms

DPYD GC SPP1

1.79e-03265273C0024121
DiseaseMalignant neoplasm of lung

DPYD GC SPP1

1.81e-03266273C0242379
Diseasemultiple sclerosis (is_implicated_in)

GC SPP1

2.04e-0373272DOID:2377 (is_implicated_in)
Diseasepreeclampsia

MYCBP2 F10

2.32e-0378272EFO_0000668
DiseaseDrug toxicity

GC SPP1

2.68e-0384272C0013221
DiseaseAdverse reaction to drug

GC SPP1

2.68e-0384272C0041755
DiseaseAcute kidney injury

GC SPP1

3.85e-03101272C2609414
DiseaseKidney Failure, Acute

GC SPP1

3.85e-03101272C0022660
DiseaseAcute Kidney Insufficiency

GC SPP1

3.85e-03101272C1565662
DiseaseLiver Cirrhosis

GC SPP1

4.00e-03103272C0023890
DiseaseFibrosis, Liver

GC SPP1

4.15e-03105272C0239946
Diseasepancreatic cancer (is_implicated_in)

DPYD SPP1

4.71e-03112272DOID:1793 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
RAVPEEMELAKEEKC

DPYD

371

Q12882
SKPREDMECDDLKEL

BAZ1A

396

Q9NRL2
HEDMLVVDPKSKEED

SPP1

281

P10451
HCSEEKEDEDYMPIK

PPIL4

391

Q8WUA2
FKLLMEHLDPDEEEE

NIPBL

2621

Q6KC79
KEMEHVLDPDSELCA

KIAA1549L

1441

Q6ZVL6
MCDEDIIKLFHPEEL

HERC5

891

Q9UII4
EFEKAMKELAEEEPH

PEX19

86

P40855
MEHICKLIDTIPDDK

BLM

376

P54132
DNKIMCHDDDDKDPV

DENND5A

586

Q6IQ26
KAMDKHNLEEEEPED

RALGDS

831

Q12967
EEMKKGHLERECMEE

F10

46

P00742
EMEPQDLELELCKKH

INPP5F

96

Q9Y2H2
EDVEPECIMEKVAKA

DBNL

121

Q9UJU6
VEKLVKMIPCEHEDL

KIFAP3

346

Q92845
EELNEMCHKPDVELL

TRIM49

231

P0CI25
HEELMLGDPCLKDLK

EPRS1

651

P07814
LSCEQEKPMHLEIED

GTF3C6

176

Q969F1
LSMLKEPPLHEKCED

MYCBP2

3121

O75592
HIMEDCDLKEPEGLL

CLBA1

241

Q96F83
EKKSDQPMCEEHEEE

TRIM55

116

Q9BYV6
YDHLDPTEMEKVEKC

HSPA4L

726

O95757
EELNEMCHKPDVELL

TRIM49C

231

P0CI26
EDCMAKELPEHTVKL

GC

271

P02774
HKDHMDKKEEIIAPC

ROCK2

1301

O75116
EHPDMLDEKDCLKEV

RALGAPB

846

Q86X10
EELNEMCHKPDVELL

TRIM49B

231

A6NDI0