Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	sodium ion binding	SCN1A SCN2A SCN3A SCN8A	3.15e-08	14	49	4	GO:0031402
GeneOntologyMolecularFunction	transporter activity	ABCA3 ABCB9 SLC25A40 TRPM3 SCN1A PIEZO1 SCN2A SCN3A SCN8A PEX12 ABCB6 ATP11A TRPM1 SLC5A8 CNGA1 ABCG8	3.64e-08	1289	49	16	GO:0005215
GeneOntologyMolecularFunction	transmembrane transporter activity	ABCA3 ABCB9 SLC25A40 TRPM3 SCN1A PIEZO1 SCN2A SCN3A SCN8A PEX12 ABCB6 TRPM1 SLC5A8 CNGA1 ABCG8	8.05e-08	1180	49	15	GO:0022857
GeneOntologyMolecularFunction	sodium channel activity	SCN1A SCN2A SCN3A SCN8A CNGA1	1.72e-07	52	49	5	GO:0005272
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	SCN1A SCN2A SCN3A SCN8A	4.60e-07	26	49	4	GO:0005248
GeneOntologyMolecularFunction	alkali metal ion binding	SCN1A SCN2A SCN3A SCN8A	4.60e-07	26	49	4	GO:0031420
GeneOntologyMolecularFunction	monoatomic cation channel activity	TRPM3 SCN1A PIEZO1 SCN2A SCN3A SCN8A TRPM1 CNGA1	1.71e-06	343	49	8	GO:0005261
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SCN1A SCN2A SCN3A SCN8A SLC5A8 CNGA1	3.72e-06	171	49	6	GO:0015081
GeneOntologyMolecularFunction	passive transmembrane transporter activity	TRPM3 SCN1A PIEZO1 SCN2A SCN3A SCN8A TRPM1 SLC5A8 CNGA1	4.59e-06	526	49	9	GO:0022803
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCA3 ABCB9 ABCB6 ABCG8	6.25e-06	49	49	4	GO:0140359
GeneOntologyMolecularFunction	monoatomic ion channel activity	TRPM3 SCN1A PIEZO1 SCN2A SCN3A SCN8A TRPM1 CNGA1	1.45e-05	459	49	8	GO:0005216
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	TRPM3 SCN1A SCN2A SCN3A SCN8A TRPM1 SLC5A8 CNGA1	1.59e-05	465	49	8	GO:0046873
GeneOntologyMolecularFunction	adiponectin binding	ADIPOR1 ADIPOR2	1.77e-05	3	49	2	GO:0055100
GeneOntologyMolecularFunction	acyltransferase activity, transferring groups other than amino-acyl groups	SAT1 HHAT HGSNAT NAA10 LPGAT1 CPT2	2.45e-05	238	49	6	GO:0016747
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	TRPM3 SCN1A PIEZO1 SCN2A SCN3A SCN8A TRPM1 SLC5A8 CNGA1	2.94e-05	664	49	9	GO:0008324
GeneOntologyMolecularFunction	adipokinetic hormone receptor activity	ADIPOR1 ADIPOR2	3.53e-05	4	49	2	GO:0097003
GeneOntologyMolecularFunction	channel activity	TRPM3 SCN1A PIEZO1 SCN2A SCN3A SCN8A TRPM1 CNGA1	3.78e-05	525	49	8	GO:0015267
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	TRPM3 SCN1A PIEZO1 SCN2A SCN3A SCN8A TRPM1 SLC5A8 CNGA1	1.16e-04	793	49	9	GO:0015075
GeneOntologyMolecularFunction	hormone binding	ADIPOR1 ADRA2C MTNR1A ADIPOR2	1.18e-04	103	49	4	GO:0042562
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	TRPM3 SCN1A SCN2A SCN3A SCN8A TRPM1 SLC5A8 CNGA1	1.31e-04	627	49	8	GO:0022890
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCA3 ABCB9 ABCB6 ABCG8	1.47e-04	109	49	4	GO:0042626
GeneOntologyMolecularFunction	O-acyltransferase activity	HHAT LPGAT1 CPT2	4.10e-04	59	49	3	GO:0008374
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	TRPM3 SCN1A SCN2A SCN3A SCN8A TRPM1 SLC5A8 CNGA1	4.72e-04	758	49	8	GO:0015318
GeneOntologyMolecularFunction	glycerophospholipid flippase activity	ABCA3 ATP11A	5.27e-04	14	49	2	GO:0140333
GeneOntologyMolecularFunction	monoacylglycerol lipase activity	DAGLB DAGLA	6.93e-04	16	49	2	GO:0047372
GeneOntologyMolecularFunction	oligopeptide transmembrane transporter activity	ABCB9 SLC25A40	6.93e-04	16	49	2	GO:0035673
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	SCN1A SCN2A	7.84e-04	17	49	2	GO:0099508
GeneOntologyMolecularFunction	flippase activity	ABCA3 ATP11A	7.84e-04	17	49	2	GO:0140327
GeneOntologyMolecularFunction	N-acetyltransferase activity	SAT1 HGSNAT NAA10	9.28e-04	78	49	3	GO:0008080
GeneOntologyMolecularFunction	primary active transmembrane transporter activity	ABCA3 ABCB9 ABCB6 ABCG8	9.46e-04	178	49	4	GO:0015399
GeneOntologyMolecularFunction	protein-hormone receptor activity	ADIPOR1 ADIPOR2	1.32e-03	22	49	2	GO:0016500
GeneOntologyMolecularFunction	lipid transporter activity	ABCA3 ATP11A SLC5A8 ABCG8	1.35e-03	196	49	4	GO:0005319
GeneOntologyMolecularFunction	triacylglycerol lipase activity	DAGLB DAGLA	1.85e-03	26	49	2	GO:0004806
GeneOntologyMolecularFunction	N-acyltransferase activity	SAT1 HGSNAT NAA10	2.01e-03	102	49	3	GO:0016410
GeneOntologyMolecularFunction	acetyltransferase activity	SAT1 HGSNAT NAA10	2.12e-03	104	49	3	GO:0016407
GeneOntologyMolecularFunction	ATPase-coupled intramembrane lipid transporter activity	ABCA3 ATP11A	2.14e-03	28	49	2	GO:0140326
GeneOntologyMolecularFunction	acyltransferase activity	SAT1 HHAT HGSNAT NAA10 LPGAT1 PEX12 CPT2	2.68e-03	775	49	7	GO:0016746
GeneOntologyMolecularFunction	palmitoyltransferase activity	HHAT CPT2	3.72e-03	37	49	2	GO:0016409
GeneOntologyMolecularFunction	ATP-dependent activity	ABCA3 ABCB9 CECR2 ABCB6 ATP11A ABCG8	3.75e-03	614	49	6	GO:0140657
GeneOntologyMolecularFunction	calcium channel activity	TRPM3 TRPM1 CNGA1	3.91e-03	129	49	3	GO:0005262
GeneOntologyMolecularFunction	ATP hydrolysis activity	ABCA3 ABCB9 ABCB6 ATP11A ABCG8	4.41e-03	441	49	5	GO:0016887
GeneOntologyMolecularFunction	lipase activity	DAGLB PLBD1 DAGLA	4.72e-03	138	49	3	GO:0016298
GeneOntologyMolecularFunction	amide transmembrane transporter activity	ABCB9 SLC25A40	4.77e-03	42	49	2	GO:0042887
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	TRPM3 TRPM1 CNGA1	6.06e-03	151	49	3	GO:0015085
GeneOntologyMolecularFunction	active transmembrane transporter activity	ABCA3 ABCB9 ABCB6 SLC5A8 ABCG8	6.12e-03	477	49	5	GO:0022804
GeneOntologyMolecularFunction	carboxylic ester hydrolase activity	DAGLB PON1 DAGLA	6.74e-03	157	49	3	GO:0052689
GeneOntologyMolecularFunction	intramembrane lipid transporter activity	ABCA3 ATP11A	6.97e-03	51	49	2	GO:0140303
GeneOntologyMolecularFunction	lipid transfer activity	ABCA3 ABCG8	8.64e-03	57	49	2	GO:0120013
GeneOntologyMolecularFunction	gated channel activity	SCN1A PIEZO1 SCN2A CNGA1	9.02e-03	334	49	4	GO:0022836
GeneOntologyMolecularFunction	phospholipid transporter activity	ABCA3 ATP11A	1.42e-02	74	49	2	GO:0005548
GeneOntologyBiologicalProcess	membrane depolarization during action potential	SCN1A SCN2A SCN3A SCN8A	1.70e-06	36	50	4	GO:0086010
GeneOntologyBiologicalProcess	membrane depolarization	SCN1A SCN2A SCN3A SCN8A CNGA1	1.10e-05	121	50	5	GO:0051899
GeneOntologyBiologicalProcess	fatty acid metabolic process	DAGLB ADIPOR1 TECR LPGAT1 CPT2 DAGLA ALOX12B ADIPOR2	1.38e-05	461	50	8	GO:0006631
GeneOntologyBiologicalProcess	cardiac muscle cell action potential involved in contraction	SCN1A SCN2A SCN3A SCN8A	1.54e-05	62	50	4	GO:0086002
GeneOntologyBiologicalProcess	neuronal action potential	SCN1A SCN2A SCN3A SCN8A	1.64e-05	63	50	4	GO:0019228
GeneOntologyBiologicalProcess	cannabinoid biosynthetic process	DAGLB DAGLA	1.73e-05	3	50	2	GO:1901696
GeneOntologyBiologicalProcess	sodium ion transport	SCN1A SCN2A SCN3A SCN8A SLC5A8 CNGA1	5.17e-05	275	50	6	GO:0006814
GeneOntologyBiologicalProcess	diacylglycerol catabolic process	DAGLB DAGLA	5.73e-05	5	50	2	GO:0046340
GeneOntologyBiologicalProcess	cardiac muscle cell action potential	SCN1A SCN2A SCN3A SCN8A	5.86e-05	87	50	4	GO:0086001
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	TRPM3 SCN1A PIEZO1 SCN2A SCN3A AGTR1 SCN8A ABCB6 TRPM1 CNGA1	7.31e-05	942	50	10	GO:0098655
GeneOntologyBiologicalProcess	cardiac muscle cell contraction	SCN1A SCN2A SCN3A SCN8A	7.61e-05	93	50	4	GO:0086003
GeneOntologyBiologicalProcess	monoatomic cation transport	TRPM3 SCN1A PIEZO1 SCN2A SCN3A AGTR1 SCN8A ABCB6 TRPM1 SLC5A8 CNGA1	8.15e-05	1157	50	11	GO:0006812
GeneOntologyBiologicalProcess	metal ion transport	TRPM3 SCN1A SCN2A SCN3A AGTR1 SCN8A ABCB6 TRPM1 SLC5A8 CNGA1	1.20e-04	1000	50	10	GO:0030001
GeneOntologyBiologicalProcess	adiponectin-activated signaling pathway	ADIPOR1 ADIPOR2	1.20e-04	7	50	2	GO:0033211
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	TRPM3 SCN1A SCN2A SCN3A AGTR1 SCN8A ABCB6 TRPM1 SLC5A8 CNGA1	1.38e-04	1017	50	10	GO:0098660
GeneOntologyBiologicalProcess	sodium ion transmembrane transport	SCN1A SCN2A SCN3A SCN8A CNGA1	1.46e-04	208	50	5	GO:0035725
GeneOntologyBiologicalProcess	transmission of nerve impulse	SCN1A SCN2A SCN3A SCN8A	1.56e-04	112	50	4	GO:0019226
GeneOntologyBiologicalProcess	lipid modification	ADIPOR1 CPT2 ALOX12B ADIPOR2 PLPP6	1.66e-04	214	50	5	GO:0030258
GeneOntologyBiologicalProcess	monoacylglycerol biosynthetic process	DAGLB DAGLA	2.05e-04	9	50	2	GO:0006640
GeneOntologyBiologicalProcess	putrescine metabolic process	AOC1 SAT1	2.05e-04	9	50	2	GO:0009445
GeneOntologyBiologicalProcess	lipid transport	ABCA3 AGTR1 PON1 ATP11A SLC5A8 CPT2 ABCG8	2.06e-04	506	50	7	GO:0006869
GeneOntologyBiologicalProcess	organic hydroxy compound transport	ABCA3 ADRA2C AGTR1 PON1 SLC5A8 ABCG8	2.19e-04	358	50	6	GO:0015850
GeneOntologyBiologicalProcess	long-chain fatty acid metabolic process	DAGLB CPT2 DAGLA ALOX12B	2.31e-04	124	50	4	GO:0001676
GeneOntologyBiologicalProcess	actin-mediated cell contraction	SCN1A SCN2A SCN3A SCN8A	2.54e-04	127	50	4	GO:0070252
GeneOntologyBiologicalProcess	lipid oxidation	ADIPOR1 CPT2 ALOX12B ADIPOR2	2.69e-04	129	50	4	GO:0034440
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	TRPM3 SCN1A PIEZO1 SCN2A SCN3A AGTR1 SCN8A ABCB6 TRPM1 CNGA1	2.91e-04	1115	50	10	GO:0034220
GeneOntologyBiologicalProcess	regulation of myotube differentiation	NLN PIEZO1 ATP11A	3.22e-04	55	50	3	GO:0010830
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	TRPM3 SCN1A SCN2A SCN3A AGTR1 SCN8A ABCB6 TRPM1 CNGA1	3.29e-04	922	50	9	GO:0098662
GeneOntologyBiologicalProcess	monocarboxylic acid metabolic process	DAGLB ADIPOR1 TECR LPGAT1 CPT2 DAGLA ALOX12B ADIPOR2	3.44e-04	731	50	8	GO:0032787
GeneOntologyBiologicalProcess	monoatomic ion transport	TRPM3 SCN1A PIEZO1 SCN2A SCN3A AGTR1 SCN8A ABCB6 TRPM1 SLC5A8 CNGA1	3.68e-04	1374	50	11	GO:0006811
GeneOntologyBiologicalProcess	lipid localization	ABCA3 AGTR1 PON1 ATP11A SLC5A8 CPT2 ABCG8	4.01e-04	565	50	7	GO:0010876
GeneOntologyBiologicalProcess	neutral lipid biosynthetic process	DAGLB LPGAT1 DAGLA	4.80e-04	63	50	3	GO:0046460
GeneOntologyBiologicalProcess	acylglycerol biosynthetic process	DAGLB LPGAT1 DAGLA	4.80e-04	63	50	3	GO:0046463
GeneOntologyBiologicalProcess	actin filament-based movement	SCN1A SCN2A SCN3A SCN8A	5.14e-04	153	50	4	GO:0030048
GeneOntologyBiologicalProcess	arachidonate metabolic process	DAGLB DAGLA ALOX12B	6.01e-04	68	50	3	GO:0019369
GeneOntologyBiologicalProcess	monoacylglycerol metabolic process	DAGLB DAGLA	6.76e-04	16	50	2	GO:0046462
GeneOntologyBiologicalProcess	G protein-coupled glutamate receptor signaling pathway	TRPM1 DAGLA	6.76e-04	16	50	2	GO:0007216
GeneOntologyBiologicalProcess	cardiac muscle contraction	SCN1A SCN2A SCN3A SCN8A	7.14e-04	167	50	4	GO:0060048
GeneOntologyBiologicalProcess	carboxylic acid metabolic process	DAGLB ADIPOR1 TECR PON1 LPGAT1 CPT2 DAGLA ALOX12B ADIPOR2	7.61e-04	1035	50	9	GO:0019752
GeneOntologyBiologicalProcess	oligopeptide transmembrane transport	ABCB9 SLC25A40	7.65e-04	17	50	2	GO:0035672
GeneOntologyBiologicalProcess	cholesterol efflux	ABCA3 PON1 ABCG8	8.64e-04	77	50	3	GO:0033344
GeneOntologyBiologicalProcess	oxoacid metabolic process	DAGLB ADIPOR1 TECR PON1 LPGAT1 CPT2 DAGLA ALOX12B ADIPOR2	8.90e-04	1058	50	9	GO:0043436
GeneOntologyBiologicalProcess	phosphatidylcholine metabolic process	ABCA3 PON1 LPGAT1	8.97e-04	78	50	3	GO:0046470
GeneOntologyBiologicalProcess	blood circulation	ADRA2C SCN1A SCN2A SCN3A AGTR1 SCN8A PON1	9.03e-04	648	50	7	GO:0008015
GeneOntologyBiologicalProcess	organic acid metabolic process	DAGLB ADIPOR1 TECR PON1 LPGAT1 CPT2 DAGLA ALOX12B ADIPOR2	9.26e-04	1064	50	9	GO:0006082
GeneOntologyBiologicalProcess	positive regulation of myotube differentiation	PIEZO1 ATP11A	9.59e-04	19	50	2	GO:0010831
GeneOntologyBiologicalProcess	polyamine metabolic process	AOC1 SAT1	1.06e-03	20	50	2	GO:0006595
GeneOntologyBiologicalProcess	fatty acid biosynthetic process	DAGLB TECR LPGAT1 ALOX12B	1.18e-03	191	50	4	GO:0006633
GeneOntologyBiologicalProcess	fatty acid transmembrane transport	SLC5A8 CPT2	1.29e-03	22	50	2	GO:1902001
GeneOntologyBiologicalProcess	oligopeptide transport	ABCB9 SLC25A40	1.41e-03	23	50	2	GO:0006857
GeneOntologyBiologicalProcess	action potential	SCN1A SCN2A SCN3A SCN8A	1.42e-03	201	50	4	GO:0001508
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR52I2 NLN ADRA2C AGTR1 MTNR1A TENM1 TAS1R2 TRPM1 DAGLA RHO	1.65e-03	1395	50	10	GO:0007186
GeneOntologyBiologicalProcess	NAD biosynthetic process	NMRK1 SLC5A8	1.80e-03	26	50	2	GO:0009435
GeneOntologyBiologicalProcess	circulatory system process	ADRA2C SCN1A SCN2A SCN3A AGTR1 SCN8A PON1	1.84e-03	733	50	7	GO:0003013
GeneOntologyBiologicalProcess	striated muscle contraction	SCN1A SCN2A SCN3A SCN8A	1.88e-03	217	50	4	GO:0006941
GeneOntologyBiologicalProcess	positive regulation of cold-induced thermogenesis	ADIPOR1 CPT2 ADIPOR2	1.94e-03	102	50	3	GO:0120162
GeneOntologyBiologicalProcess	positive regulation of cholesterol efflux	ABCA3 PON1	1.94e-03	27	50	2	GO:0010875
GeneOntologyBiologicalProcess	diacylglycerol metabolic process	DAGLB DAGLA	2.09e-03	28	50	2	GO:0046339
GeneOntologyBiologicalProcess	phospholipid transport	ABCA3 ATP11A ABCG8	2.17e-03	106	50	3	GO:0015914
GeneOntologyBiologicalProcess	regulation of membrane potential	SCN1A PIEZO1 SCN2A SCN3A SCN8A CNGA1	2.23e-03	559	50	6	GO:0042391
GeneOntologyBiologicalProcess	N-terminal protein amino acid modification	HHAT NAA10	2.24e-03	29	50	2	GO:0031365
GeneOntologyBiologicalProcess	lipid catabolic process	DAGLB PLBD1 CPT2 DAGLA PLPP6	2.27e-03	382	50	5	GO:0016042
GeneOntologyBiologicalProcess	visual perception	CRYGS TRPM1 CNGA1 RHO	2.32e-03	230	50	4	GO:0007601
GeneOntologyBiologicalProcess	nerve development	SCN1A SCN2A SCN8A	2.35e-03	109	50	3	GO:0021675
GeneOntologyBiologicalProcess	nicotinamide nucleotide biosynthetic process	NMRK1 SLC5A8	2.40e-03	30	50	2	GO:0019359
GeneOntologyBiologicalProcess	pyridine nucleotide biosynthetic process	NMRK1 SLC5A8	2.40e-03	30	50	2	GO:0019363
GeneOntologyBiologicalProcess	sensory perception of light stimulus	CRYGS TRPM1 CNGA1 RHO	2.43e-03	233	50	4	GO:0050953
GeneOntologyBiologicalProcess	muscle contraction	ADRA2C SCN1A SCN2A SCN3A SCN8A	2.77e-03	400	50	5	GO:0006936
GeneOntologyBiologicalProcess	cellular catabolic process	DAGLB PLBD1 NLN HGSNAT PON1 CPT2 WDFY4 DAGLA PLPP6	2.87e-03	1253	50	9	GO:0044248
GeneOntologyBiologicalProcess	pyridine-containing compound biosynthetic process	NMRK1 SLC5A8	3.07e-03	34	50	2	GO:0072525
GeneOntologyBiologicalProcess	phospholipid metabolic process	PLBD1 ABCA3 PON1 LPGAT1 PLPP6	3.08e-03	410	50	5	GO:0006644
GeneOntologyBiologicalProcess	biogenic amine metabolic process	AOC1 SAT1 AGTR1	3.16e-03	121	50	3	GO:0006576
GeneOntologyBiologicalProcess	fatty acid oxidation	ADIPOR1 CPT2 ADIPOR2	3.23e-03	122	50	3	GO:0019395
GeneOntologyBiologicalProcess	phosphatidylglycerol metabolic process	ABCA3 LPGAT1	3.26e-03	35	50	2	GO:0046471
GeneOntologyBiologicalProcess	lipid biosynthetic process	DAGLB ABCA3 TECR LPGAT1 DAGLA ALOX12B PLPP6	3.28e-03	813	50	7	GO:0008610
GeneOntologyBiologicalProcess	regulation of striated muscle cell differentiation	NLN PIEZO1 ATP11A	3.31e-03	123	50	3	GO:0051153
GeneOntologyBiologicalProcess	plasma lipoprotein particle remodeling	AGTR1 PON1	3.44e-03	36	50	2	GO:0034369
GeneOntologyBiologicalProcess	protein-lipid complex remodeling	AGTR1 PON1	3.44e-03	36	50	2	GO:0034368
GeneOntologyCellularComponent	voltage-gated sodium channel complex	SCN1A SCN2A SCN3A SCN8A	7.30e-08	17	51	4	GO:0001518
GeneOntologyCellularComponent	transporter complex	NDUFAF1 SCN1A SCN2A SCN3A SCN8A PEX12 ABCB6 ATP11A CNGA1 ABCG8	7.10e-07	550	51	10	GO:1990351
GeneOntologyCellularComponent	sodium channel complex	SCN1A SCN2A SCN3A SCN8A	7.13e-07	29	51	4	GO:0034706
GeneOntologyCellularComponent	node of Ranvier	SCN1A SCN2A SCN8A	1.51e-05	20	51	3	GO:0033268
GeneOntologyCellularComponent	transmembrane transporter complex	NDUFAF1 SCN1A SCN2A SCN3A SCN8A ABCB6 CNGA1 ABCG8	3.60e-05	523	51	8	GO:1902495
GeneOntologyCellularComponent	axon initial segment	SCN1A SCN2A SCN8A	4.78e-05	29	51	3	GO:0043194
GeneOntologyCellularComponent	endoplasmic reticulum membrane	ABCB9 PIEZO1 TECR HHAT PON1 LPGAT1 ABCB6 ATP11A TRPM1 PLPP6 STT3B RHO	4.97e-05	1293	51	12	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	ABCB9 PIEZO1 TECR HHAT PON1 LPGAT1 ABCB6 ATP11A TRPM1 PLPP6 STT3B RHO	5.20e-05	1299	51	12	GO:0098827
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	ABCB9 PIEZO1 TECR HHAT PON1 LPGAT1 ABCB6 ATP11A TRPM1 PLPP6 STT3B RHO	6.39e-05	1327	51	12	GO:0042175
GeneOntologyCellularComponent	main axon	SCN1A SCN2A SCN8A DAGLA	6.58e-05	89	51	4	GO:0044304
GeneOntologyCellularComponent	ATP-binding cassette (ABC) transporter complex	ABCB6 ABCG8	8.70e-05	6	51	2	GO:0043190
GeneOntologyCellularComponent	rod photoreceptor outer segment	CNGA1 RHO	2.08e-04	9	51	2	GO:0120200
GeneOntologyCellularComponent	cation channel complex	SCN1A SCN2A SCN3A SCN8A CNGA1	2.65e-04	235	51	5	GO:0034703
GeneOntologyCellularComponent	lysosomal membrane	DAGLB ABCA3 ABCB9 HGSNAT ABCB6 ATP11A	8.75e-04	462	51	6	GO:0005765
GeneOntologyCellularComponent	lytic vacuole membrane	DAGLB ABCA3 ABCB9 HGSNAT ABCB6 ATP11A	8.75e-04	462	51	6	GO:0098852
GeneOntologyCellularComponent	photoreceptor outer segment membrane	CNGA1 RHO	9.72e-04	19	51	2	GO:0042622
GeneOntologyCellularComponent	axon	ADRA2C SCN1A SCN2A SCN3A SCN8A TRPM1 CNGA1 DAGLA	1.32e-03	891	51	8	GO:0030424
GeneOntologyCellularComponent	vacuolar membrane	DAGLB ABCA3 ABCB9 HGSNAT ABCB6 ATP11A	1.41e-03	507	51	6	GO:0005774
GeneOntologyCellularComponent	endosome	ABCA3 ADRA2C ABCB9 AGTR1 ABCB6 ATP11A WDFY4 DAGLA DOP1A	1.86e-03	1167	51	9	GO:0005768
GeneOntologyCellularComponent	monoatomic ion channel complex	SCN1A SCN2A SCN3A SCN8A CNGA1	2.24e-03	378	51	5	GO:0034702
GeneOntologyCellularComponent	multivesicular body membrane	ABCA3 ABCB6	2.43e-03	30	51	2	GO:0032585
GeneOntologyCellularComponent	lysosome	DAGLB PLBD1 ABCA3 ABCB9 HGSNAT ABCB6 ATP11A	3.37e-03	811	51	7	GO:0005764
GeneOntologyCellularComponent	lytic vacuole	DAGLB PLBD1 ABCA3 ABCB9 HGSNAT ABCB6 ATP11A	3.37e-03	811	51	7	GO:0000323
GeneOntologyCellularComponent	cell projection membrane	PIEZO1 SLC5A8 CNGA1 DAGLA RHO	3.92e-03	431	51	5	GO:0031253
GeneOntologyCellularComponent	early endosome	ABCB9 ABCB6 ATP11A WDFY4 DAGLA	6.22e-03	481	51	5	GO:0005769
GeneOntologyCellularComponent	vacuole	DAGLB PLBD1 ABCA3 ABCB9 HGSNAT ABCB6 ATP11A	6.42e-03	913	51	7	GO:0005773
GeneOntologyCellularComponent	postsynaptic density membrane	ADRA2C SCN8A DAGLA	6.65e-03	157	51	3	GO:0098839
GeneOntologyCellularComponent	specific granule	AOC1 HGSNAT ATP11A	7.00e-03	160	51	3	GO:0042581
GeneOntologyCellularComponent	ATPase dependent transmembrane transport complex	ABCB6 ABCG8	7.98e-03	55	51	2	GO:0098533
HumanPheno	Simple febrile seizure	SCN1A SCN2A SCN3A SCN8A	1.01e-05	27	27	4	HP:0011171
HumanPheno	Focal automatism seizure	SCN1A SCN2A SCN8A	2.83e-05	12	27	3	HP:0032898
HumanPheno	Complex febrile seizure	SCN1A SCN2A SCN8A	7.10e-05	16	27	3	HP:0011172
HumanPheno	Episodic hemolytic anemia	ABCB6 ABCG8	8.09e-05	3	27	2	HP:0004802
HumanPheno	Macrovesicular hepatic steatosis	NDUFAF1 NAA10 CPT2	8.60e-05	17	27	3	HP:0001403
HumanPheno	Dermatological manifestations of systemic disorders	ABCA3 SAT1 SCN1A PIEZO1 SCN2A SCN8A NAA10 PEX12 ATP11A	2.58e-04	435	27	9	HP:0001005
HumanPheno	Neonatal electro-clinical non-motor seizure	SCN2A SCN8A	2.68e-04	5	27	2	HP:0032812
HumanPheno	Neonatal seizure with electrographic correlate	SCN2A SCN8A	2.68e-04	5	27	2	HP:0032808
HumanPheno	Neonatal electro-clinical seizure	SCN2A SCN8A	2.68e-04	5	27	2	HP:0032809
HumanPheno	Neonatal electro-clinical seizure with behavior arrest	SCN2A SCN8A	2.68e-04	5	27	2	HP:0032823
HumanPheno	Focal head nodding automatism seizure	SCN2A SCN8A	2.68e-04	5	27	2	HP:0032906
HumanPheno	Focal hemiclonic seizure	SCN1A SCN2A SCN8A	2.83e-04	25	27	3	HP:0006813
HumanPheno	Intellectual disability, borderline	SCN3A SCN8A ALOX12B	2.83e-04	25	27	3	HP:0006889
HumanPheno	Cyanosis	ABCA3 SCN1A SCN2A SCN8A ATP11A	3.16e-04	117	27	5	HP:0000961
MousePheno	absent b-wave	TRPM1 RHO	3.17e-05	3	46	2	MP:0020439
Domain	Na_trans_cytopl	SCN1A SCN2A SCN3A SCN8A	7.37e-10	6	51	4	PF11933
Domain	Na_trans_cytopl	SCN1A SCN2A SCN3A SCN8A	7.37e-10	6	51	4	IPR024583
Domain	Na_channel_asu	SCN1A SCN2A SCN3A SCN8A	1.02e-08	10	51	4	IPR001696
Domain	Na_trans_assoc	SCN1A SCN2A SCN3A SCN8A	1.02e-08	10	51	4	IPR010526
Domain	Na_trans_assoc	SCN1A SCN2A SCN3A SCN8A	1.02e-08	10	51	4	PF06512
Domain	Ion_trans_dom	TRPM3 SCN1A SCN2A SCN3A SCN8A TRPM1 CNGA1	2.43e-08	114	51	7	IPR005821
Domain	Ion_trans	TRPM3 SCN1A SCN2A SCN3A SCN8A TRPM1 CNGA1	2.43e-08	114	51	7	PF00520
Domain	ABC_transporter_CS	ABCA3 ABCB9 ABCB6 ABCG8	5.11e-06	42	51	4	IPR017871
Domain	Fungal_lipase-like	DAGLB DAGLA	7.31e-06	2	51	2	IPR002921
Domain	Lipase_3	DAGLB DAGLA	7.31e-06	2	51	2	PF01764
Domain	ABC_TRANSPORTER_2	ABCA3 ABCB9 ABCB6 ABCG8	8.78e-06	48	51	4	PS50893
Domain	ABC_tran	ABCA3 ABCB9 ABCB6 ABCG8	8.78e-06	48	51	4	PF00005
Domain	ABC_TRANSPORTER_1	ABCA3 ABCB9 ABCB6 ABCG8	9.54e-06	49	51	4	PS00211
Domain	ABC_transporter-like	ABCA3 ABCB9 ABCB6 ABCG8	1.04e-05	50	51	4	IPR003439
Domain	Channel_four-helix_dom	SCN1A SCN2A SCN3A SCN8A	1.75e-05	57	51	4	IPR027359
Domain	-	SCN1A SCN2A SCN3A SCN8A	1.75e-05	57	51	4	1.20.120.350
Domain	TRPM_tetra	TRPM3 TRPM1	4.37e-05	4	51	2	PF16519
Domain	TRPM_tetra	TRPM3 TRPM1	4.37e-05	4	51	2	IPR032415
Domain	IQ	SCN1A SCN2A SCN3A SCN8A	7.03e-05	81	51	4	SM00015
Domain	IQ_motif_EF-hand-BS	SCN1A SCN2A SCN3A SCN8A	1.06e-04	90	51	4	IPR000048
Domain	IQ	SCN1A SCN2A SCN3A SCN8A	1.20e-04	93	51	4	PS50096
Domain	7TM_GPCR_Srsx	ADRA2C AGTR1 MTNR1A RHO	2.46e-04	112	51	4	SM01381
Domain	AdipoR/HlyIII-related	ADIPOR1 ADIPOR2	3.96e-04	11	51	2	IPR004254
Domain	HlyIII	ADIPOR1 ADIPOR2	3.96e-04	11	51	2	PF03006
Domain	IQ	SCN1A SCN3A SCN8A	9.62e-04	71	51	3	PF00612
Domain	Acetyltransf_1	SAT1 NAA10	1.78e-03	23	51	2	PF00583
Domain	ABC_membrane	ABCB9 ABCB6	1.94e-03	24	51	2	PF00664
Domain	GNAT	SAT1 NAA10	2.11e-03	25	51	2	PS51186
Domain	GNAT_dom	SAT1 NAA10	2.11e-03	25	51	2	IPR000182
Domain	LIPASE_SER	DAGLB DAGLA	2.28e-03	26	51	2	PS00120
Domain	ABC_TM1F	ABCB9 ABCB6	2.64e-03	28	51	2	PS50929
Domain	ABC1_TM_dom	ABCB9 ABCB6	2.64e-03	28	51	2	IPR011527
Domain	-	TENM1 PON1	5.08e-03	39	51	2	2.120.10.30
Domain	-	SAT1 NAA10	5.34e-03	40	51	2	3.40.630.30
Domain	Acyl_CoA_acyltransferase	SAT1 NAA10	6.71e-03	45	51	2	IPR016181
Domain	6-blade_b-propeller_TolB-like	TENM1 PON1	7.01e-03	46	51	2	IPR011042
Domain	AAA+_ATPase	ABCA3 ABCB9 ABCB6	7.13e-03	144	51	3	IPR003593
Domain	AAA	ABCA3 ABCB9 ABCB6	7.13e-03	144	51	3	SM00382
Pathway	WP_DRAVET_SYNDROME	SCN1A SCN2A SCN3A SCN8A	1.92e-06	28	46	4	M45519
Pathway	WP_ADHD_AND_AUTISM_ASD_PATHWAYS	DAGLB AOC1 SLC25A40 SCN1A SCN2A SCN3A AGTR1 SCN8A DAGLA	2.34e-06	367	46	9	M48346
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SCN1A SCN2A SCN3A SCN8A	2.93e-06	31	46	4	M877
Pathway	REACTOME_PHASE_0_RAPID_DEPOLARISATION	SCN1A SCN2A SCN3A SCN8A	3.34e-06	32	46	4	M27455
Pathway	KEGG_ABC_TRANSPORTERS	ABCA3 ABCB9 ABCB6 ABCG8	1.22e-05	44	46	4	M11911
Pathway	WP_RETT_SYNDROME	CECR2 SCN1A SCN2A SCN8A	1.74e-05	48	46	4	M39759
Pathway	REACTOME_ARACHIDONATE_PRODUCTION_FROM_DAG	DAGLB DAGLA	1.04e-04	5	46	2	M27338
Pathway	REACTOME_ARACHIDONATE_PRODUCTION_FROM_DAG	DAGLB DAGLA	1.04e-04	5	46	2	MM15080
Pathway	REACTOME_AMPK_INHIBITS_CHREBP_TRANSCRIPTIONAL_ACTIVATION_ACTIVITY	ADIPOR1 ADIPOR2	1.55e-04	6	46	2	MM14630
Pathway	REACTOME_AMPK_INHIBITS_CHREBP_TRANSCRIPTIONAL_ACTIVATION_ACTIVITY	ADIPOR1 ADIPOR2	2.88e-04	8	46	2	M26990
Pathway	REACTOME_ACTIVATION_OF_THE_PHOTOTRANSDUCTION_CASCADE	CNGA1 RHO	2.88e-04	8	46	2	MM14893
Pathway	REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT	ABCA3 ABCB9 ABCB6 ABCG8	2.98e-04	99	46	4	MM14986
Pathway	REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT	ABCA3 ABCB9 ABCB6 ABCG8	3.47e-04	103	46	4	M758
Pathway	WP_LEPTIN_AND_ADIPONECTIN	ADIPOR1 ADIPOR2	4.61e-04	10	46	2	M39539
Pathway	WP_LEPTIN_AND_ADIPONECTIN	ADIPOR1 ADIPOR2	4.61e-04	10	46	2	MM15824
Pathway	REACTOME_SENSORY_PERCEPTION_OF_TASTE	SCN2A SCN3A TAS1R2	4.77e-04	47	46	3	M42524
Pathway	REACTOME_ACTIVATION_OF_THE_PHOTOTRANSDUCTION_CASCADE	CNGA1 RHO	5.62e-04	11	46	2	M27180
Pathway	REACTOME_L1CAM_INTERACTIONS	SCN1A SCN2A SCN3A SCN8A	6.38e-04	121	46	4	M872
Pathway	REACTOME_CARDIAC_CONDUCTION	SCN1A SCN2A SCN3A SCN8A	8.35e-04	130	46	4	M27454
Pathway	REACTOME_SIGNALING_BY_GPCR	DAGLB NLN ADRA2C AGTR1 MTNR1A TAS1R2 DAGLA RHO	1.04e-03	646	46	8	MM14962
Pathway	KEGG_RENIN_ANGIOTENSIN_SYSTEM	NLN AGTR1	1.37e-03	17	46	2	M17636
Pathway	REACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS	ABCA3 ABCG8	1.37e-03	17	46	2	MM14552
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	ABCA3 ABCB9 TRPM3 ABCB6 ATP11A TRPM1 SLC5A8 ABCG8	1.46e-03	681	46	8	MM14985
Pathway	REACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS	ABCA3 ABCG8	1.54e-03	18	46	2	M524
Pathway	REACTOME_INTEGRATION_OF_ENERGY_METABOLISM	ADIPOR1 ADRA2C ADIPOR2	1.66e-03	72	46	3	MM14631
Pathway	REACTOME_SIGNALING_BY_GPCR	DAGLB NLN ADRA2C AGTR1 MTNR1A TAS1R2 DAGLA RHO	1.76e-03	702	46	8	M746
Pathway	REACTOME_ABC_TRANSPORTER_DISORDERS	ABCA3 ABCB6 ABCG8	2.08e-03	78	46	3	M27473
Pathway	REACTOME_FATTY_ACID_METABOLISM	TECR PON1 CPT2 ALOX12B	2.25e-03	170	46	4	MM15573
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	ABCA3 ABCB9 TRPM3 ABCB6 ATP11A TRPM1 SLC5A8 ABCG8	2.38e-03	736	46	8	M27287
Pathway	PID_RHODOPSIN_PATHWAY	CNGA1 RHO	2.52e-03	23	46	2	M204
Pathway	REACTOME_SURFACTANT_METABOLISM	ABCA3 ADRA2C	2.52e-03	23	46	2	MM15279
Pathway	REACTOME_FATTY_ACID_METABOLISM	TECR PON1 CPT2 ALOX12B	2.55e-03	176	46	4	M27854
Pathway	REACTOME_GPCR_LIGAND_BINDING	NLN ADRA2C AGTR1 MTNR1A TAS1R2 RHO	2.59e-03	430	46	6	MM15160
Pathway	REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS	DAGLB DAGLA	2.98e-03	25	46	2	MM14511
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	ADRA2C AGTR1 MTNR1A RHO	3.11e-03	186	46	4	MM15994
Pathway	REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS	DAGLB DAGLA	3.47e-03	27	46	2	M12123
Pathway	REACTOME_METABOLISM_OF_LIPIDS	PLBD1 TECR PON1 LPGAT1 CPT2 ALOX12B PLPP6	3.70e-03	620	46	7	MM15193
Pathway	REACTOME_TRP_CHANNELS	TRPM3 TRPM1	3.73e-03	28	46	2	MM14943
Pathway	REACTOME_TRP_CHANNELS	TRPM3 TRPM1	3.73e-03	28	46	2	M27241
Pathway	REACTOME_GPCR_LIGAND_BINDING	NLN ADRA2C AGTR1 MTNR1A TAS1R2 RHO	3.74e-03	463	46	6	M507
Pathway	WP_CANNABINOID_RECEPTOR_SIGNALING	DAGLB DAGLA	4.00e-03	29	46	2	M39676
Pathway	REACTOME_MUSCLE_CONTRACTION	SCN1A SCN2A SCN3A SCN8A	4.25e-03	203	46	4	M5485
Pathway	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	NLN ADRA2C AGTR1 MTNR1A RHO	4.26e-03	330	46	5	M18334
Pathway	REACTOME_SURFACTANT_METABOLISM	ABCA3 ADRA2C	4.28e-03	30	46	2	M27566
Pathway	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	NLN ADRA2C AGTR1 MTNR1A RHO	4.42e-03	333	46	5	MM14963
Pathway	REACTOME_NICOTINATE_METABOLISM	NMRK1 SLC5A8	4.56e-03	31	46	2	M27089
Pathway	REACTOME_NICOTINATE_METABOLISM	NMRK1 SLC5A8	4.56e-03	31	46	2	MM14767
Pathway	REACTOME_THE_PHOTOTRANSDUCTION_CASCADE	CNGA1 RHO	4.56e-03	31	46	2	MM14896
Pathway	WP_MITOCHONDRIAL_IMMUNE_RESPONSE_TO_SARSCOV2	NDUFAF1 AGTR1	5.16e-03	33	46	2	M40066
Pathway	PID_NCADHERIN_PATHWAY	DAGLB DAGLA	5.16e-03	33	46	2	M266
Pathway	REACTOME_INTEGRATION_OF_ENERGY_METABOLISM	ADIPOR1 ADRA2C ADIPOR2	5.23e-03	108	46	3	M17034
Pathway	REACTOME_THE_PHOTOTRANSDUCTION_CASCADE	CNGA1 RHO	5.47e-03	34	46	2	M27183
Pubmed	Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.	SCN1A SCN2A SCN3A SCN8A	4.80e-12	4	53	4	17537961
Pubmed	Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.	SCN1A SCN2A SCN3A SCN8A	4.80e-12	4	53	4	35031483
Pubmed	Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.	SCN1A SCN2A SCN3A SCN8A	4.80e-12	4	53	4	29578003
Pubmed	A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.	SCN1A SCN2A SCN3A SCN8A	7.19e-11	6	53	4	23652591
Pubmed	International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.	SCN1A SCN2A SCN3A SCN8A	6.02e-10	9	53	4	16382098
Pubmed	Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.	SCN1A SCN2A SCN3A SCN8A	6.02e-10	9	53	4	15746173
Pubmed	Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.	SCN1A SCN2A SCN3A SCN8A	2.36e-09	12	53	4	30175250
Pubmed	Sodium channels SCN1A, SCN2A and SCN3A in familial autism.	SCN1A SCN2A SCN3A	3.34e-09	3	53	3	12610651
Pubmed	SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.	SCN1A SCN2A SCN3A	3.34e-09	3	53	3	23859570
Pubmed	Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.	SCN1A SCN2A SCN3A	3.34e-09	3	53	3	18784617
Pubmed	Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.	SCN1A SCN2A SCN3A	3.34e-09	3	53	3	17544618
Pubmed	Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.	SCN1A SCN2A SCN8A	3.34e-09	3	53	3	32845893
Pubmed	Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.	SCN1A SCN2A SCN8A	3.34e-09	3	53	3	28518218
Pubmed	Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.	SCN1A SCN2A SCN8A	3.34e-09	3	53	3	17928448
Pubmed	Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.	SCN1A SCN2A SCN3A	3.34e-09	3	53	3	14973256
Pubmed	Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.	SCN1A SCN2A SCN3A SCN8A	3.40e-09	13	53	4	15123669
Pubmed	Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.	SCN1A SCN2A SCN8A	1.34e-08	4	53	3	21156207
Pubmed	Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.	SCN1A SCN2A SCN3A	1.34e-08	4	53	3	35801810
Pubmed	Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.	SCN1A SCN2A SCN3A	1.34e-08	4	53	3	8974318
Pubmed	Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.	SCN1A SCN2A SCN3A	3.33e-08	5	53	3	1679748
Pubmed	A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.	SCN1A SCN2A SCN3A	3.33e-08	5	53	3	8812438
Pubmed	Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.	SCN2A SCN3A SCN8A	3.33e-08	5	53	3	17724025
Pubmed	Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.	SCN1A SCN2A SCN3A	3.33e-08	5	53	3	24337656
Pubmed	Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.	SCN1A SCN2A SCN8A	1.16e-07	7	53	3	25818041
Pubmed	Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice.	SCN1A SCN2A SCN3A	7.28e-07	12	53	3	8169823
Pubmed	Confirmation of quantitative trait loci for alcohol preference in mice.	SCN1A SCN2A SCN3A	1.50e-06	15	53	3	9726281
Pubmed	Adiponectin receptor-1 expression is decreased in the pancreas of obese mice.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	19062045
Pubmed	Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.	SCN1A SCN2A	2.28e-06	2	53	2	29649454
Pubmed	Cardiomyocyte-derived adiponectin is biologically active in protecting against myocardial ischemia-reperfusion injury.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	20028965
Pubmed	Transient receptor potential melastatin 1 (TRPM1) is an ion-conducting plasma membrane channel inhibited by zinc ions.	TRPM3 TRPM1	2.28e-06	2	53	2	21278253
Pubmed	Lack of any prognostic relationship between adiponectin receptor (Adipo R1/R2) expression for early/advanced stage gastric cancer.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	24969908
Pubmed	Adiponectin and adiponectin receptor in relation to colorectal cancer progression.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	21351255
Pubmed	Array-CGH detection of a de novo 2.8 Mb deletion in 2q24.2-->q24.3 in a girl with autistic features and developmental delay.	SCN2A SCN3A	2.28e-06	2	53	2	20346423
Pubmed	Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy.	SCN1A SCN8A	2.28e-06	2	53	2	37901435
Pubmed	Arterial stiffness is associated with increased monocyte expression of adiponectin receptor mRNA and protein in patients with coronary artery disease.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	22534793
Pubmed	Expression of adiponectin receptor mRNA in human skeletal muscle cells is related to in vivo parameters of glucose and lipid metabolism.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	15331527
Pubmed	Omental fat expression of adiponectin and adiponectin receptors in non-obese women with PCOS: a preliminary study.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	19909601
Pubmed	An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.	SCN1A SCN8A	2.28e-06	2	53	2	26410685
Pubmed	The role of AdipoR1 and AdipoR2 in liver fibrosis.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	29237572
Pubmed	Variations in adiponectin receptor genes and susceptibility to type 2 diabetes in women: a tagging-single nucleotide polymorphism haplotype analysis.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	17416799
Pubmed	Muscle-specific overexpression of AdipoR1 or AdipoR2 gives rise to common and discrete local effects whilst AdipoR2 promotes additional systemic effects.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	28145500
Pubmed	AdipoR agonist increases insulin sensitivity and exercise endurance in AdipoR-humanized mice.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	33420419
Pubmed	Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.	SCN1A SCN2A	2.28e-06	2	53	2	10827969
Pubmed	Adiponectin receptor expression predicts favorable prognosis in cases of hepatocellular carcinoma.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	24619866
Pubmed	Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.	SCN1A SCN2A	2.28e-06	2	53	2	19694741
Pubmed	Commonalities and distinctions between two neurodevelopmental disorder subtypes associated with SCN2A and SCN8A variants and literature review.	SCN2A SCN8A	2.28e-06	2	53	2	35348308
Pubmed	Overexpression of adiponectin receptors potentiates the antiinflammatory action of subeffective dose of globular adiponectin in vascular endothelial cells.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	18988888
Pubmed	Genomic structures of SCN2A and SCN3A - candidate genes for deafness at the DFNA16 locus.	SCN2A SCN3A	2.28e-06	2	53	2	11245985
Pubmed	Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain.	DAGLB DAGLA	2.28e-06	2	53	2	14610053
Pubmed	Involvement of AdipoR receptor in adiponectin-induced motility and alpha2beta1 integrin upregulation in human chondrosarcoma cells.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	19549705
Pubmed	Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice.	DAGLB DAGLA	2.28e-06	2	53	2	20147530
Pubmed	Electrophysiological properties of two axonal sodium channels, Nav1.2 and Nav1.6, expressed in mouse spinal sensory neurones.	SCN2A SCN8A	2.28e-06	2	53	2	15760941
Pubmed	Macrophage polarization phenotype regulates adiponectin receptor expression and adiponectin anti-inflammatory response.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	25392268
Pubmed	Pattern of expression of adiponectin receptors in human liver and its relation to nonalcoholic steatohepatitis.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	18923878
Pubmed	Absence of an association between the polymorphisms in the genes encoding adiponectin receptors and type 2 diabetes.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	15918014
Pubmed	The adiponectin receptors AdipoR1 and AdipoR2 activate ERK1/2 through a Src/Ras-dependent pathway and stimulate cell growth.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	18842004
Pubmed	Differential expression of two sodium channel subtypes in human brain.	SCN1A SCN2A	2.28e-06	2	53	2	1317301
Pubmed	Postsynaptic diacylglycerol lipase mediates retrograde endocannabinoid suppression of inhibition in mouse prefrontal cortex.	DAGLB DAGLA	2.28e-06	2	53	2	21807615
Pubmed	Duplication of the sodium channel gene cluster on 2q24 in children with early onset epilepsy.	SCN2A SCN3A	2.28e-06	2	53	2	23016767
Pubmed	Adiponectin receptor genes: mutation screening in syndromes of insulin resistance and association studies for type 2 diabetes and metabolic traits in UK populations.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	17216283
Pubmed	Dual action of adiponectin on insulin secretion in insulin-resistant mice.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	15358228
Pubmed	Regulation of adiponectin receptor gene expression in diabetic mice.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	15613685
Pubmed	Whole gene duplication of SCN2A and SCN3A is associated with neonatal seizures and a normal intellectual development.	SCN2A SCN3A	2.28e-06	2	53	2	27153334
Pubmed	Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.	SCN1A SCN2A	2.28e-06	2	53	2	33096315
Pubmed	Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.	SCN1A SCN3A	2.28e-06	2	53	2	24990319
Pubmed	Association of sequence variations in the gene encoding adiponectin receptor 1 (ADIPOR1) with body size and insulin levels. The Finnish Diabetes Prevention Study.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	16724230
Pubmed	DAGL-Beta Functions as a PUFA-Specific Triacylglycerol Lipase in Macrophages.	DAGLB DAGLA	2.28e-06	2	53	2	31991095
Pubmed	Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.	SCN1A SCN2A	2.28e-06	2	53	2	31439038
Pubmed	Demonstration of adiponectin receptors 1 and 2 mRNA expression in human breast cancer cells.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	17123704
Pubmed	AdipoR1 and AdipoR2 maintain membrane fluidity in most human cell types and independently of adiponectin.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	30890562
Pubmed	Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition.	DAGLB DAGLA	2.28e-06	2	53	2	26668358
Pubmed	The regulation of adiponectin receptors in human prostate cancer cell lines.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	16899222
Pubmed	Polymorphisms in adiponectin receptor genes are associated with lipodystrophy-related phenotypes in HIV-infected patients receiving antiretroviral therapy.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	26111083
Pubmed	Upregulation of adiponectin receptor 1 and 2 mRNA and protein in adipose tissue and adipocytes in insulin-resistant women with polycystic ovary syndrome.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	17001470
Pubmed	Association of Adiponectin Receptors with Metabolic and Immune Homeostasis Parameters in Colorectal Cancer: In Silico Analysis and Observational Findings.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	36429712
Pubmed	Expression of adiponectin receptors in mouse adrenal glands and the adrenocortical Y-1 cell line: adiponectin regulates steroidogenesis.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	19878661
Pubmed	Variations in ADIPOR1 But Not ADIPOR2 are Associated With Hypertriglyceridemia and Diabetes in an Admixed Latin American Population.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	29145541
Pubmed	Sodium channel expression within chronic multiple sclerosis plaques.	SCN2A SCN8A	2.28e-06	2	53	2	17805013
Pubmed	AdipoR-increased intracellular ROS promotes cPLA2 and COX-2 expressions via activation of PKC and p300 in adiponectin-stimulated human alveolar type II cells.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	27288489
Pubmed	Adiponectin receptor expression in gastric carcinoma: implications in tumor development and progression.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	23358721
Pubmed	Missense mutations in sodium channel SCN1A and SCN2A predispose children to encephalopathy with severe febrile seizures.	SCN1A SCN2A	2.28e-06	2	53	2	26311622
Pubmed	Expression profiles of adiponectin receptors in mouse embryos.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	15939384
Pubmed	Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy.	SCN1A SCN8A	2.28e-06	2	53	2	33411788
Pubmed	Expression and biologic significance of adiponectin receptors in papillary thyroid carcinoma.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	22907586
Pubmed	Characterisation of the adiponectin receptors: Differential cell-surface expression and temporal signalling profiles of AdipoR1 and AdipoR2 are regulated by the non-conserved N-terminal trunks.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	25892445
Pubmed	Adiponectin receptors form homomers and heteromers exhibiting distinct ligand binding and intracellular signaling properties.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	23255609
Pubmed	Polymorphisms in adiponectin receptor genes ADIPOR1 and ADIPOR2 and insulin resistance.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	17716299
Pubmed	Low-abundant adiponectin receptors in visceral adipose tissue of humans and rats are further reduced in diabetic animals.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	20470935
Pubmed	Adipo-R1 and adipo-R2 expression in colorectal adenomas and carcinomas.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	25640382
Pubmed	The expression and relationship of AdipoR1/R2 in gastric intestinal metaplasia.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	33851685
Pubmed	Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoR1 and AdipoR2.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	17459059
Pubmed	Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome.	SCN1A SCN8A	2.28e-06	2	53	2	31943325
Pubmed	Adiponectin receptor expression is elevated in colorectal carcinomas but not in gastrointestinal stromal tumors.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	18310295
Pubmed	The effect of renal transplantation on adiponectin and its isoforms and receptors.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	17697862
Pubmed	Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	21186369
Pubmed	Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.	SCN1A SCN2A	2.28e-06	2	53	2	15249644
Pubmed	Expressions of adiponectin receptors in placenta and their correlation with preeclampsia.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	19487733
Pubmed	Polymorphisms of ADIPOR1 and ADIPOR2 are associated with phenotypes of type 2 diabetes in Koreans.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	18466348
Pubmed	Association of ADIPOR2 with liver function tests in type 2 diabetic subjects.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	18719649
Pubmed	Adiponectin receptors are expressed in hypothalamus and colocalized with proopiomelanocortin and neuropeptide Y in rodent arcuate neurons.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	18971219
Interaction	SCN4B interactions	SCN1A SCN2A SCN8A	8.47e-07	8	51	3	int:SCN4B
Interaction	TTYH1 interactions	DAGLB ABCA3 NDUFAF1 ABCB9 PIEZO1 ABCB6 DAGLA	9.98e-06	300	51	7	int:TTYH1
Interaction	GPBAR1 interactions	NDUFAF1 SLC25A40 LPGAT1	6.53e-05	31	51	3	int:GPBAR1
Interaction	MBOAT1 interactions	TECR PRSS21 LPGAT1	7.90e-05	33	51	3	int:MBOAT1
Interaction	LRRC25 interactions	DAGLB NCAPD3 NDUFAF1 SLC25A40 ABCB6	1.03e-04	185	51	5	int:LRRC25
Interaction	C3orf52 interactions	DAGLB ABCA3 ABCB9 PIEZO1 LPGAT1 DAGLA	1.16e-04	305	51	6	int:C3orf52
Cytoband	2q24.3	SCN1A SCN2A	1.55e-04	16	53	2	2q24.3
Cytoband	Ensembl 112 genes in cytogenetic band chr2q24	SCN1A SCN2A SCN3A	4.38e-04	127	53	3	chr2q24
Cytoband	11q12.2	MS4A4E DAGLA	9.43e-04	39	53	2	11q12.2
Cytoband	1q32	HHAT LPGAT1	1.49e-03	49	53	2	1q32
Cytoband	Ensembl 112 genes in cytogenetic band chr1q32	ADIPOR1 HHAT LPGAT1	4.63e-03	290	53	3	chr1q32
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN1A SCN2A SCN3A SCN8A	2.31e-09	9	39	4	1203
GeneFamily	Adiponectin receptors\|Progestin and adipoQ receptor family	ADIPOR1 ADIPOR2	4.53e-06	2	39	2	293
GeneFamily	Progestin and adipoQ receptor family	ADIPOR1 ADIPOR2	2.46e-04	11	39	2	930
GeneFamily	ATP binding cassette subfamily B	ABCB9 ABCB6	2.46e-04	11	39	2	806
GeneFamily	Lipases\|Arylacetamide deacetylase family	DAGLB DAGLA	1.02e-03	22	39	2	464
GeneFamily	GCN5 related N-acetyltransferases	SAT1 NAA10	1.21e-03	24	39	2	1134
GeneFamily	Transient receptor potential cation channels	TRPM3 TRPM1	1.65e-03	28	39	2	249
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	ABCA3 CECR2 SCN1A ATP11A SLC5A8	2.38e-06	180	53	5	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	AOC1 TRPM3 SCN2A SCN3A CNGA1	3.26e-06	192	53	5	0bb06738e1c3ec0c044a7ee61f6cf1d4781fb53c
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	AOC1 TRPM3 SCN2A SCN3A CNGA1	3.43e-06	194	53	5	be869e186386d03ebb670971dd24fa656b4b0edf
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	AOC1 TRPM3 SCN2A SCN3A CNGA1	3.43e-06	194	53	5	4d6c9b016e3a0641954a8ea10c97d1cd76fadd9f
ToppCell	severe-Lymphocytic-B_cells_2\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	SCN2A SCN3A PON1 WDFY4	2.08e-05	136	53	4	56a7b5c2e098b4a49124d1b905257a52eb38b519
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crh_4930553C11Rik_\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CRYGS AGTR1 PRSS21 MTNR1A	2.40e-05	141	53	4	ad9a25569c142fb68ded34aeba0cd9be8124ce56
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM3 PIEZO1 SCN2A CNGA1	3.14e-05	151	53	4	f4f7156b2c0cfc78fd1841e07c9915d97ced561f
ToppCell	367C-Epithelial_cells-Epithelial-B_(AT2)\|367C / Donor, Lineage, Cell class and subclass (all cells)	ABCA3 CECR2 SCN1A SLC5A8	4.76e-05	168	53	4	e20e1936573fdde78426d7a4eb45c458d5c4dbb4
ToppCell	367C-Epithelial_cells-Epithelial-B_(AT2)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	ABCA3 CECR2 SCN1A SLC5A8	4.76e-05	168	53	4	16b517e3159ad6e6d25fd48f7d5f46e77b2b318d
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic-erythrocytic-erythroid_lineage_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ADIPOR1 TRPM1 CNGA1 RHO	4.99e-05	170	53	4	288014dedda8babc51fe08e48a55e68d83e1b1d2
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_2\|368C / Donor, Lineage, Cell class and subclass (all cells)	CRYGS ABCB9 PIEZO1 DAGLA	5.10e-05	171	53	4	26b34dc069cc15b75a0c13cb8c5d81e074788160
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SAT1 CECR2 SCN2A SCN3A	5.83e-05	177	53	4	dc846d0feb94d4c289553cc3ac9dac81d10409cb
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM3 SCN2A SCN3A CNGA1	5.83e-05	177	53	4	f35b04c3557ebbdeba37dec54c8f45880eafb422
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO1 SCN2A SCN3A CNGA1	6.09e-05	179	53	4	d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SAT1 CECR2 SCN2A SCN3A	6.50e-05	182	53	4	5f513bbb7125956eb528e3120de3fd776770a7c3
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM3 SCN2A SCN3A CNGA1	6.64e-05	183	53	4	b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM3 SCN2A SCN3A CNGA1	6.64e-05	183	53	4	d340ab5a77e8d819a1dfb4ca3e9a4b9bc988923c
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABCA3 TRPM3 CECR2 ATP11A	6.78e-05	184	53	4	42ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	ABCA3 SCN1A ATP11A SLC5A8	6.78e-05	184	53	4	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	Control-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABCA3 TRPM3 CECR2 ATP11A	6.92e-05	185	53	4	0d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABCA3 SAT1 SCN1A ATP11A	7.07e-05	186	53	4	acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABCA3 TRPM3 CECR2 ATP11A	7.07e-05	186	53	4	4e94158db52df41d71e67b02b9895a358eebee0f
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABCA3 TRPM3 CECR2 ATP11A	7.22e-05	187	53	4	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM3 SCN2A SCN3A CNGA1	7.22e-05	187	53	4	f6217d0dd425eac76900b44a4e48f45475f3ac36
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM3 SCN2A SCN3A CNGA1	7.22e-05	187	53	4	2d17408b3b5f09d135084fd7ccce98e6b5ca632b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM3 SCN2A SCN3A CNGA1	7.22e-05	187	53	4	e3095455d2f255854f339f6b05fa87852af0700f
ToppCell	IPF-Epithelial-ATII\|Epithelial / Disease state, Lineage and Cell class	ABCA3 CECR2 ATP11A SLC5A8	7.37e-05	188	53	4	5f5fad2773e421760e67dbace23fd1f847a2e1e0
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABCA3 TRPM3 CECR2 ATP11A	7.37e-05	188	53	4	43a0508d2524a5b310e89e9422843dcaab999bc3
ToppCell	COVID-19-kidney-DCT\|kidney / Disease (COVID-19 only), tissue and cell type	SAT1 CECR2 SCN2A SCN3A	7.37e-05	188	53	4	df1fd0819d301679f3c9ea404e942e39095912eb
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM3 SCN2A SCN3A CNGA1	7.52e-05	189	53	4	3a295c215b5c18e7c673f92b7af5be523421682c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM3 PIEZO1 SCN2A CNGA1	7.52e-05	189	53	4	fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D231\|Adult / Lineage, Cell type, age group and donor	ABCA3 CECR2 SCN1A ATP11A	7.52e-05	189	53	4	dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM3 SCN2A SCN3A CNGA1	7.52e-05	189	53	4	532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ABCA3 CECR2 SCN1A ATP11A	7.83e-05	191	53	4	a0332a4ef629510fb313ec119195c44a3f704a80
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	ABCA3 SCN1A ATP11A SLC5A8	7.83e-05	191	53	4	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D122\|Adult / Lineage, Cell type, age group and donor	ABCA3 CECR2 SCN1A SLC5A8	7.99e-05	192	53	4	06013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell	Epithelial-alveolar_epithelial_cell_type_2\|World / Lineage, Cell type, age group and donor	ABCA3 CECR2 SCN1A ATP11A	7.99e-05	192	53	4	58c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2\|Adult / Lineage, Cell type, age group and donor	ABCA3 CECR2 SCN1A ATP11A	8.15e-05	193	53	4	738f4f0a9ddde2432b429ab46838e353b1790589
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ABCA3 CECR2 SCN1A ATP11A	8.15e-05	193	53	4	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AOC1 TRPM3 SCN3A CNGA1	8.15e-05	193	53	4	e7012f7b53971972299db34fa51ff51a4e4987fe
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ABCA3 CECR2 SCN1A ATP11A	8.15e-05	193	53	4	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO1 SCN2A SCN3A CNGA1	8.32e-05	194	53	4	69bff17df4a760ccf081cf52ff04af02c14f448d
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO1 SCN2A SCN3A CNGA1	8.32e-05	194	53	4	04bfc555743f7d8821439d05ae442d15e9886c59
ToppCell	COVID-19-Myeloid-Monocyte-derived_macrophages\|COVID-19 / group, cell type (main and fine annotations)	SAT1 DNAAF9 WDFY4 MS4A4E	8.49e-05	195	53	4	c172c5599379c29123340621a36bfb1fc90c2115
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA3 CECR2 SCN1A ATP11A	8.65e-05	196	53	4	7e5addaa844e66f8160e05858c341866a80aed23
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA3 SCN1A ATP11A RHO	8.65e-05	196	53	4	65e161fd672e37a5d10f28011bb422c4d7042d6a
ToppCell	AT2_cells-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	ABCA3 SCN1A ATP11A SLC5A8	8.83e-05	197	53	4	fd7bdfa6bf5966ebc11fdd13915769429540ddbf
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA3 CECR2 SCN1A ATP11A	8.83e-05	197	53	4	bf10727fbe90b71d2ac60a11711e5f0701b3799d
ToppCell	Severe-Plasmablast\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ABCB9 TECR NMRK1 STT3B	8.83e-05	197	53	4	1089aa7991812378668d0f3d57f8000e6245a713
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA3 CECR2 SCN1A ATP11A	9.00e-05	198	53	4	2e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SCN1A SCN2A SCN3A SCN8A	9.00e-05	198	53	4	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SCN1A SCN2A SCN3A SCN8A	9.00e-05	198	53	4	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA3 CECR2 SCN1A ATP11A	9.00e-05	198	53	4	f948391296c261c473d339069a6d0f20ccd6f38f
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SCN1A SCN2A SCN3A SCN8A	9.00e-05	198	53	4	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD14\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DAGLB WDFY4 MS4A4E ALOX12B	9.18e-05	199	53	4	1413156b7be5373fd02bbe39ec50ccfe165fa6d1
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA3 CECR2 SCN1A ATP11A	9.18e-05	199	53	4	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA3 CECR2 SCN1A ATP11A	9.18e-05	199	53	4	725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA3 CECR2 SCN1A ATP11A	9.18e-05	199	53	4	8587bd98de7767a575088afbea07a1feb4516b9b
ToppCell	Biopsy_Other_PF-Epithelial-AT2\|Biopsy_Other_PF / Sample group, Lineage and Cell type	ABCA3 SCN1A ATP11A SLC5A8	9.18e-05	199	53	4	9a65acfe9bf500db72142469cf17bf0973540001
ToppCell	Bronchial-10x5prime-Epithelial-Epi_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA3 SCN1A ATP11A SLC5A8	9.18e-05	199	53	4	a38a981cffa61c8444a980916de7414e689a1b63
ToppCell	343B-Epithelial_cells-Epithelial-B_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ABCA3 SAT1 SCN1A ATP11A	9.18e-05	199	53	4	df157604a7e2b6e7fa2d21660ca749a3552b945c
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	AOC1 SAT1 PIEZO1 SCN2A	9.18e-05	199	53	4	5059a1d4df7d9989c922007a8dcba98b1f5687d5
ToppCell	343B-Epithelial_cells-Epithelial-B_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ABCA3 SAT1 SCN1A ATP11A	9.18e-05	199	53	4	48626e54ce94b5ea3001fc5d447509a50c073aa4
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	AOC1 SAT1 PIEZO1 SCN2A	9.18e-05	199	53	4	a4ebb0598e9a0c9f6e39a0db6d0623654c2a7d88
ToppCell	Biopsy_IPF-Epithelial-AT2\|Biopsy_IPF / Sample group, Lineage and Cell type	ABCA3 SCN1A ATP11A SLC5A8	9.18e-05	199	53	4	c841d475703d3489161fb7904526bd7563d5fb0f
ToppCell	Bronchial-10x5prime-Epithelial-Epi_alveolar-AT2\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA3 SCN1A ATP11A SLC5A8	9.36e-05	200	53	4	b535323e18d9fb0dde1e0026df142c831e48c29f
ToppCell	Macroglial-Polydendrocytes-PDGFRA---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	SCN1A SCN2A SCN3A TENM1	9.36e-05	200	53	4	4fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / Treatment groups by lineage, cell group, cell type	ABCA3 TRPM3 CECR2 ATP11A	9.36e-05	200	53	4	2dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCell	Macroglial-Polydendrocytes-PDGFRA-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	SCN1A SCN2A SCN3A TENM1	9.36e-05	200	53	4	f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCell	Macroglial-Polydendrocytes-PDGFRA--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	SCN1A SCN2A SCN3A TENM1	9.36e-05	200	53	4	cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCell	Macroglial-Polydendrocytes-PDGFRA----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	SCN1A SCN2A SCN3A TENM1	9.36e-05	200	53	4	310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCell	Macroglial-Polydendrocytes-PDGFRA\|Macroglial / cells hierarchy compared to all cells using T-Statistic	SCN1A SCN2A SCN3A TENM1	9.36e-05	200	53	4	c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCell	Macroglial-Polydendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	SCN1A SCN2A SCN3A TENM1	9.36e-05	200	53	4	961858738ce35db8760c8c2e136f8369bc444ccf
Drug	N-(p-amylcinnamoyl)anthranilic acid	DAGLB TRPM3 AGTR1 DAGLA	2.38e-08	14	52	4	CID000001974
Drug	APETx1, Anthopleura elegantissima	SCN2A SCN3A SCN8A	2.24e-07	6	52	3	ctd:C475726
Drug	2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate	SCN2A SCN3A SCN8A	6.24e-07	8	52	3	ctd:C489827
Drug	Zonisamide	SCN1A SCN2A SCN3A	7.47e-06	17	52	3	DB00909
Drug	palmitoylacetylglycerol	DAGLB DAGLA	1.53e-05	3	52	2	CID000146026
Drug	metformin	NDUFAF1 SCN2A AGTR1 PON1 CPT2 ADIPOR2	1.55e-05	235	52	6	CID000004091
Drug	APETx2 protein, Anthopleura elegantissima	SCN2A SCN8A	3.06e-05	4	52	2	ctd:C501880
Drug	nafazatrom	DAGLB DAGLA ALOX12B	3.94e-05	29	52	3	CID000042923
Drug	Sodium	SCN2A SCN3A SCN8A SLC5A8	4.08e-05	84	52	4	ctd:D012964
Drug	guanosine 3',5'-cyclic monophosphoric acid	ADIPOR1 NDUFAF1 AGTR1 MTNR1A CNGA1 ALOX12B ADIPOR2 RHO	4.57e-05	577	52	8	CID000000295
Drug	AC1L9K72	DAGLB PLBD1 PEX12 DAGLA ALOX12B RHO	5.05e-05	290	52	6	CID000446872
Drug	1-stearoyl-2-arachidonoylglycerol	DAGLB DAGLA	5.09e-05	5	52	2	ctd:C075809
Drug	lauroylcarnitine	DAGLB DAGLA	5.09e-05	5	52	2	CID000168381
Drug	1-acetyl-sn-glycero-3-phosphocholine	DAGLB TRPM3 PON1 LPGAT1 DAGLA ALOX12B	6.67e-05	305	52	6	CID005311264
Drug	lecithin	DAGLB PLBD1 SAT1 PON1 DAGLA RHO	6.67e-05	305	52	6	CID010425705
Drug	1-methylanthracene	DAGLB DAGLA	7.63e-05	6	52	2	CID000011884
Drug	fenpropathrin	SCN2A SCN3A	7.63e-05	6	52	2	ctd:C044267
Drug	aminoparathion	PON1 SLC5A8	7.63e-05	6	52	2	CID000000220
Drug	Indoprofen [31842-01-0]; Up 200; 14.2uM; PC3; HT_HG-U133A	ABCB9 TRPM3 HHAT SCN2A AGTR1	8.61e-05	197	52	5	4249_UP
Drug	nordihydroguaiaretic acid; Up 200; 1uM; PC3; HT_HG-U133A	PLBD1 AGTR1 PRSS21 PON1 ATP11A	9.25e-05	200	52	5	4447_UP
Drug	bosentan	SLC25A40 TRPM3 AGTR1 TRPM1	1.01e-04	106	52	4	CID000104865
Drug	Tetrodotoxin	SCN2A SCN3A SCN8A	1.05e-04	40	52	3	ctd:D013779
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN1A SCN2A SCN3A SCN8A	1.79e-09	10	52	4	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN1A SCN2A SCN3A SCN8A	1.79e-09	10	52	4	DOID:0080422 (implicated_via_orthology)
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN1A SCN2A SCN3A SCN8A	4.20e-09	12	52	4	DOID:0060170 (implicated_via_orthology)
Disease	hyperinsulinism (biomarker_via_orthology)	ADIPOR1 AGTR1 ADIPOR2	2.31e-06	15	52	3	DOID:2018 (biomarker_via_orthology)
Disease	anxiety disorder (implicated_via_orthology)	SCN1A SCN2A SCN3A	7.76e-06	22	52	3	DOID:2030 (implicated_via_orthology)
Disease	Benign familial infantile epilepsy	SCN2A SCN8A	9.13e-06	3	52	2	cv:C5575231
Disease	Familial benign neonatal epilepsy	SCN2A SCN8A	4.55e-05	6	52	2	C0220669
Disease	Seizure, Febrile, Simple	SCN1A SCN2A	6.36e-05	7	52	2	C0149886
Disease	Seizure, Febrile, Complex	SCN1A SCN2A	6.36e-05	7	52	2	C0751057
Disease	MASA syndrome (implicated_via_orthology)	TRPM3 TRPM1	6.36e-05	7	52	2	DOID:0060246 (implicated_via_orthology)
Disease	Febrile Convulsions	SCN1A SCN2A	1.09e-04	9	52	2	C0009952
Disease	Generalized Epilepsy with Febrile Seizures Plus	SCN1A SCN2A	1.09e-04	9	52	2	C3502809
Disease	Diabetic Retinopathy	AGTR1 PON1	1.66e-04	11	52	2	C0011884
Disease	epilepsy (implicated_via_orthology)	SCN1A SCN2A SCN3A SCN8A	1.98e-04	163	52	4	DOID:1826 (implicated_via_orthology)
Disease	X-Linked Csnb	TRPM1 RHO	1.99e-04	12	52	2	C3711543
Disease	Night blindness, congenital stationary, type 1	TRPM1 RHO	1.99e-04	12	52	2	C3501847
Disease	Night Blindness, Congenital Stationary, Type 1A	TRPM1 RHO	1.99e-04	12	52	2	C3495587
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2B (disorder)	TRPM1 RHO	1.99e-04	12	52	2	C1864877
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2A	TRPM1 RHO	1.99e-04	12	52	2	C1848172
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 1B	TRPM1 RHO	1.99e-04	12	52	2	C1850362
Disease	Infantile Severe Myoclonic Epilepsy	SCN1A SCN2A	2.35e-04	13	52	2	C0751122
Disease	Cone-rod synaptic disorder, congenital nonprogressive	TRPM1 RHO	2.35e-04	13	52	2	C4041558
Disease	Hamman-Rich syndrome	ABCA3 ATP11A	2.73e-04	14	52	2	C0085786
Disease	MMR-related febrile seizures	SCN1A SCN2A	3.15e-04	15	52	2	EFO_0006519
Disease	Early infantile epileptic encephalopathy with suppression bursts	SCN1A SCN2A	3.60e-04	16	52	2	C0393706
Disease	Night blindness, congenital stationary	TRPM1 RHO	4.07e-04	17	52	2	C0339535
Disease	Epilepsy, Cryptogenic	SCN1A SCN2A SCN8A	4.14e-04	82	52	3	C0086237
Disease	Awakening Epilepsy	SCN1A SCN2A SCN8A	4.14e-04	82	52	3	C0751111
Disease	Aura	SCN1A SCN2A SCN8A	4.14e-04	82	52	3	C0236018
Disease	Febrile seizure (within the age range of 3 months to 6 years)	SCN1A SCN2A	4.58e-04	18	52	2	HP_0002373
Disease	Hypercholesterolemia, Familial	PON1 ABCG8	4.58e-04	18	52	2	C0020445
Disease	Neurodevelopmental Disorders	SCN1A SCN2A SCN8A	5.99e-04	93	52	3	C1535926
Disease	Idiopathic Pulmonary Fibrosis	ABCA3 ATP11A	6.26e-04	21	52	2	C1800706
Disease	Retinitis Pigmentosa	HGSNAT CNGA1 RHO	8.29e-04	104	52	3	C0035334
Disease	Epilepsy	SCN1A SCN2A SCN8A	9.50e-04	109	52	3	C0014544
Disease	Myocardial Failure	ADRA2C AGTR1 PON1	9.75e-04	110	52	3	C1959583
Disease	Congestive heart failure	ADRA2C AGTR1 PON1	9.75e-04	110	52	3	C0018802
Disease	Heart failure	ADRA2C AGTR1 PON1	9.75e-04	110	52	3	C0018801
Disease	Left-Sided Heart Failure	ADRA2C AGTR1 PON1	9.75e-04	110	52	3	C0023212
Disease	Heart Failure, Right-Sided	ADRA2C AGTR1 PON1	9.75e-04	110	52	3	C0235527
Disease	Heart Decompensation	ADRA2C AGTR1 PON1	9.75e-04	110	52	3	C1961112
Disease	macular degeneration (is_implicated_in)	ADIPOR1 PON1	1.04e-03	27	52	2	DOID:4448 (is_implicated_in)
Disease	Subfertility, Female	ADIPOR1 ADIPOR2	1.12e-03	28	52	2	C0341869
Disease	Sterility, Postpartum	ADIPOR1 ADIPOR2	1.12e-03	28	52	2	C0038279
Disease	Female sterility	ADIPOR1 ADIPOR2	1.12e-03	28	52	2	C0917730
Disease	Female infertility	ADIPOR1 ADIPOR2	1.12e-03	28	52	2	C0021361
Disease	severe acute respiratory syndrome, COVID-19	NLN CECR2 ATP11A TRPM1 WDFY4	1.13e-03	447	52	5	EFO_0000694, MONDO_0100096
Disease	Intellectual Disability	TRPM3 SCN1A SCN3A SCN8A STT3B	1.13e-03	447	52	5	C3714756
Disease	arteriosclerosis (is_implicated_in)	PON1 ABCG8	1.37e-03	31	52	2	DOID:2349 (is_implicated_in)
Disease	Bipolar Disorder	ADRA2C SAT1 SCN2A SCN8A PON1	1.50e-03	477	52	5	C0005586

Protein segments in the cluster

Peptide	Gene	Start	Entry
VYTAMEYRWPFGNYL	AGTR1	86	P30556
PFSLANELMAYWYFG	ADRA2C	106	P18825
YIPYFFVAPRYNWMT	ABCA3	386	Q99758
YIIQLYMPLNWFGTY	ABCB6	536	Q9NP58
YMPLNWFGTYYRMIQ	ABCB6	541	Q9NP58
AYIIIYGMPTYWLAN	ABCG8	506	Q9H221
FNSFEPYYMWDYVAR	DOP1A	426	Q5JWR5
YDYIWDFIFYPNGVM	AOC1	461	P19801
YWYFYGTRMYKEDPV	CECR2	156	Q9BXF3
WYGAYLVNAYPLDMS	CPT2	201	P23786
LIMGSFVPWLYYSFY	ADIPOR2	226	Q86V24
YPQYYLAEPWQFSML	RHO	26	P08100
IMGSFVPWLYYSFYC	ADIPOR1	216	Q96A54
AFLSGYMWYNIIQYF	LPGAT1	351	Q92604
YQMKYYFYHGLSWPQ	NAA10	26	P41227
YTFTGYYMHWVRQAP	IGHV1-2	46	P23083
KPAGVYYATAYWMPA	PLBD1	36	Q6P4A8
FPWMLAYVFYYPVLH	HHAT	201	Q5VTY9
YMQFAAAAYGWPLYI	DAGLB	281	Q8NCG7
TWAVYERPNFAGYMY	CRYGS	46	P22914
MYSYFMFTRGGPYWQ	NDUFAF1	236	Q9Y375
RYLMYPGWYEGKLNA	DNAAF9	951	Q5TEA3
YVAYTIWGSVMYPYQ	MS4A4E	81	Q96PG1
IYHFPAYQWMDGYET	ALOX12B	96	O75342
EVCYYMLFALAAYGW	DAGLA	291	Q9Y4D2
LMVFVNYGGGKYWYF	HGSNAT	281	Q68CP4
LTGVYYAMYNGQWDL	FAM126B	241	Q8IXS8
YYLPGMASIYAAWLG	OR52I2	281	Q8NH67
GYFDGHVWPMYLKYR	NMRK1	141	Q9NWW6
MYLGLAWSYVVYYSP	PON1	196	P27169
DVPFSAMYWYNYEIL	SLC25A40	206	Q8TBP6
PLMDNWYSLSYLYFS	SLC5A8	511	Q8N695
FIEYMDQGPWYLAFY	TENM1	496	Q9UKZ4
IVGFAMYYFTYDPWI	SAT1	71	P21673
MYYFTYDPWIGKLLY	SAT1	76	P21673
IIAMDPYYYFQEGWN	SCN3A	811	Q9NY46
YRAFLAAYPFVNMAW	PEX12	156	O00623
AMDPYYYFQEGWNIF	SCN1A	821	P35498
EMLLKWVAYGYQTYF	SCN1A	1266	P35498
LNRKEAAAYMYYVWG	ABCB9	401	Q9NP78
PCGEYAMFIAWLYKY	NCAPD3	386	P42695
YYNWLFCITLPVMYN	CNGA1	161	P29973
GVIWPFLNYQRMYYV	ATP11A	1051	P98196
EYDGKINAWDLYYYM	NLN	351	Q9BYT8
YFYMVSAWGGYVFII	STT3B	256	Q8TCJ2
YMPYWMIYGEVFADQ	TRPM3	1071	Q9HCF6
IAMDPYYYFQEGWNI	SCN2A	811	Q99250
DYMQYPVFPWVLADY	WDFY4	2566	Q6ZS81
AMDPYYYFQEGWNIF	SCN8A	806	Q9UQD0
FAAWMAYYINHPLYT	TECR	171	Q9NZ01
YWVRYQGPYVSMAFI	TAS1R2	671	Q8TE23
FLGYMQYSIVDYCWL	PLPP6	266	Q8IY26
NIFYMPYWMIYGEVF	TRPM1	1001	Q7Z4N2
GFMLLFYQYLYPWQS	XKR3	391	Q5GH77
MPSFWSLQAYYTRYF	PRSS21	106	Q9Y6M0
YAKYWIYVCAGMFIV	PIEZO1	576	Q92508
RIPEWLFVASYYMAY	MTNR1A	271	P48039