Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	K63-linked deubiquitinase activity	USP8 OTUD5 OTUD4	3.60e-05	16	82	3	GO:0061578
GeneOntologyCellularComponent	super elongation complex	AFF2 AFF4	2.31e-04	6	83	2	GO:0032783
MousePheno	decreased fetal weight	STAC3 EHMT1 WDFY3 NIPBL LIN28A	2.84e-05	77	65	5	MP:0009431
MousePheno	abnormal auditory brainstem response	AGAP5 COCH MCTP1 AP3B2 SCN8A ADAMTS15 USP39 AGAP9 MYO18B NIPBL MGRN1	6.25e-05	576	65	11	MP:0004738
MousePheno	abnormal hearing electrophysiology	AGAP5 COCH MCTP1 AP3B2 SCN8A ADAMTS15 USP39 AGAP9 MYO18B NIPBL MGRN1	8.23e-05	594	65	11	MP:0006335
Domain	TF_AF4/FMR2	AFF2 AFF4	1.05e-04	4	79	2	IPR007797
Domain	AF-4	AFF2 AFF4	1.05e-04	4	79	2	PF05110
Domain	IQ	SCN8A CAMTA1 MYO18B IQCE	2.32e-04	71	79	4	PF00612
Domain	PreSET	SETMAR EHMT1	3.66e-04	7	79	2	SM00468
Domain	Pre-SET	SETMAR EHMT1	3.66e-04	7	79	2	PF05033
Domain	Pre-SET_dom	SETMAR EHMT1	3.66e-04	7	79	2	IPR007728
Domain	PRE_SET	SETMAR EHMT1	3.66e-04	7	79	2	PS50867
Domain	IQ	SCN8A CAMTA1 MYO18B IQCE	3.85e-04	81	79	4	SM00015
Domain	IQ_motif_EF-hand-BS	SCN8A CAMTA1 MYO18B IQCE	5.75e-04	90	79	4	IPR000048
Domain	IQ	SCN8A CAMTA1 MYO18B IQCE	6.51e-04	93	79	4	PS50096
Domain	TCP1_1	CCT8L2 CCT5	7.78e-04	10	79	2	PS00750
Domain	TCP1_2	CCT8L2 CCT5	7.78e-04	10	79	2	PS00751
Domain	TCP1_3	CCT8L2 CCT5	7.78e-04	10	79	2	PS00995
Domain	Chaperone_TCP-1	CCT8L2 CCT5	7.78e-04	10	79	2	IPR017998
Domain	-	CCT8L2 CCT5	9.48e-04	11	79	2	3.30.260.10
Domain	TCP-1-like_intermed	CCT8L2 CCT5	9.48e-04	11	79	2	IPR027410
Domain	DUF4599	SPATA31A7 SPATA31A5	1.13e-03	12	79	2	PF15371
Domain	DUF4599	SPATA31A7 SPATA31A5	1.13e-03	12	79	2	IPR027970
Domain	OTU	OTUD5 OTUD4	1.34e-03	13	79	2	PF02338
Domain	-	CCT8L2 CCT5	1.56e-03	14	79	2	1.10.560.10
Domain	GROEL-like_equatorial	CCT8L2 CCT5	1.56e-03	14	79	2	IPR027413
Domain	OTU	OTUD5 OTUD4	1.79e-03	15	79	2	PS50802
Domain	Cpn60/TCP-1	CCT8L2 CCT5	1.79e-03	15	79	2	IPR002423
Domain	Cpn60_TCP1	CCT8L2 CCT5	1.79e-03	15	79	2	PF00118
Domain	-	CCT8L2 CCT5	1.79e-03	15	79	2	3.50.7.10
Domain	GroEL-like_apical_dom	CCT8L2 CCT5	1.79e-03	15	79	2	IPR027409
Domain	OTU_dom	OTUD5 OTUD4	1.79e-03	15	79	2	IPR003323
Domain	RHOD	USP8 CEP41	3.86e-03	22	79	2	SM00450
Domain	RHODANESE_3	USP8 CEP41	4.22e-03	23	79	2	PS50206
Domain	Rhodanese-like_dom	USP8 CEP41	4.59e-03	24	79	2	IPR001763
Domain	Rhodanese	USP8 CEP41	4.59e-03	24	79	2	PF00581
Domain	-	USP8 CEP41	4.59e-03	24	79	2	3.40.250.10
Domain	ArfGap	AGAP5 AGAP9	6.66e-03	29	79	2	SM00105
Domain	ArfGap	AGAP5 AGAP9	6.66e-03	29	79	2	PF01412
Domain	ARFGAP	AGAP5 AGAP9	6.66e-03	29	79	2	PS50115
Domain	ArfGAP	AGAP5 AGAP9	6.66e-03	29	79	2	IPR001164
Pubmed	The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.	SPATA31A1 SPATA31A7 SPATA31A5	2.80e-07	6	85	3	20850414
Pubmed	Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.	SPATA31A1 SPATA31A7 SPATA31A5	2.80e-07	6	85	3	25930072
Pubmed	Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.	SPATA31A1 SPATA31A7 MYO18B SPATA31A5	3.40e-07	24	85	4	32212159
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	EEF1G ABCF1 CCT5 ATF7IP ZMYND8 CAST EHMT1 NIPBL	1.61e-06	332	85	8	32786267
Pubmed	Characterization of the DOT1L network: implications of diverse roles for DOT1L.	MLLT6 CHD1 NIPBL AFF4	3.14e-06	41	85	4	20431927
Pubmed	T-cell acute lymphoblastic leukemia--the associated gene SCL/tal codes for a 42-Kd nuclear phosphoprotein.	TAL1 TAL2	5.90e-06	2	85	2	1450410
Pubmed	Identification of Amino Acid Residues in Fibroblast Growth Factor 14 (FGF14) Required for Structure-Function Interactions with Voltage-gated Sodium Channel Nav1.6.	SCN8A FGF14	5.90e-06	2	85	2	26994141
Pubmed	The fibroblast growth factor 14·voltage-gated sodium channel complex is a new target of glycogen synthase kinase 3 (GSK3).	SCN8A FGF14	5.90e-06	2	85	2	23640885
Pubmed	Mapping of the FGF14:Nav1.6 complex interface reveals FLPK as a functionally active peptide modulating excitability.	SCN8A FGF14	5.90e-06	2	85	2	32671946
Pubmed	The leukemic oncogene tal-2 is expressed in the developing mouse brain.	TAL1 TAL2	5.90e-06	2	85	2	9931488
Pubmed	Bioluminescence methodology for the detection of protein-protein interactions within the voltage-gated sodium channel macromolecular complex.	SCN8A FGF14	5.90e-06	2	85	2	22364545
Pubmed	FGF14 localization and organization of the axon initial segment.	SCN8A FGF14	5.90e-06	2	85	2	23891806
Pubmed	Fragile XE-associated familial mental retardation protein 2 (FMR2) acts as a potent transcription activator.	AFF2 AFF4	5.90e-06	2	85	2	11355014
Pubmed	Functional Modulation of Voltage-Gated Sodium Channels by a FGF14-Based Peptidomimetic.	SCN8A FGF14	5.90e-06	2	85	2	29359916
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	PKNOX2 AFF2 ZMYND8 MLLT6 CAMTA1 FAM186B IQCE MGRN1	1.07e-05	430	85	8	35044719
Pubmed	Functional characterization of the AFF (AF4/FMR2) family of RNA-binding proteins: insights into the molecular pathology of FRAXE intellectual disability.	AFF2 AFF4	1.77e-05	3	85	2	21330300
Pubmed	JAK2 regulates Nav1.6 channel function via FGF14Y158 phosphorylation.	SCN8A FGF14	1.77e-05	3	85	2	32599005
Pubmed	TAL1, TAL2 and LYL1: a family of basic helix-loop-helix proteins implicated in T cell acute leukaemia.	TAL1 TAL2	1.77e-05	3	85	2	8142619
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	EEF1G REXO4 ATF7IP ZC3H13 ZMYND8 CAST AFDN MLLT6 CHD1 NIPBL AFF4	2.09e-05	954	85	11	36373674
Pubmed	Identifying a kinase network regulating FGF14:Nav1.6 complex assembly using split-luciferase complementation.	SCN8A FGF14	3.53e-05	4	85	2	25659151
Pubmed	Impaired conditioned fear and enhanced long-term potentiation in Fmr2 knock-out mice.	AFF2 AFF4	3.53e-05	4	85	2	11923441
Pubmed	Usp39 is essential for mitotic spindle checkpoint integrity and controls mRNA-levels of aurora B.	USP8 USP39	3.53e-05	4	85	2	18728397
Pubmed	Mediation of Af4 protein function in the cerebellum by Siah proteins.	AFF2 AFF4	3.53e-05	4	85	2	15459319
Pubmed	Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia.	TAL1 TAL2	5.87e-05	5	85	2	7957052
Pubmed	[Application of reverse transcription-multiplex nested PCR to detect MLL rearrangement in AML-M4/M5].	AFDN MLLT6	5.87e-05	5	85	2	16086288
Pubmed	Pathogenic mechanism of recurrent mutations of SCN8A in epileptic encephalopathy.	SCN8A FGF14	5.87e-05	5	85	2	26900580
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	USP8 SETMAR ABCF1 LARP6 ZMYND8 AFDN WDFY3 ST18 NIPBL AFF4 SEZ6L MICU1	6.71e-05	1285	85	12	35914814
Pubmed	Deubiquitinase USP8 increases ID1 stability and promotes esophageal squamous cell carcinoma tumorigenesis.	USP8 USP39	8.80e-05	6	85	2	35636624
Pubmed	Genome-wide association study of chronic periodontitis in a general German population.	ZNF385D SETMAR ADAMTS15 CHD1	9.30e-05	96	85	4	24024966
Pubmed	Deubiquitylation and stabilization of PTEN by USP13.	USP8 USP39	1.23e-04	7	85	2	24270891
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	FSIP2 REXO4 EHMT1 MLLT6 CHD1 USP39 NIPBL AFF4	1.23e-04	608	85	8	36089195
Pubmed	Gbx2 is essential for maintaining thalamic neuron identity and repressing habenular characters in the developing thalamus.	KIF26A TAL1 TAL2	1.30e-04	40	85	3	26297811
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	EEF1G REXO4 ABCF1 CCT5 EHMT1 AFDN CHD1 USP39 MYO18B NIPBL SLC27A4 POLR3A	1.77e-04	1425	85	12	30948266
Pubmed	GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins.	AGAP5 AGAP9	2.10e-04	9	85	2	12640130
Pubmed	AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.	AGAP5 AGAP9	2.62e-04	10	85	2	20664521
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	EEF1G REXO4 ABCF1 CCT5 ZMYND8 EHMT1 OTUD4 AFDN CHD1 NIPBL AFF4 MICU1	2.78e-04	1497	85	12	31527615
Pubmed	DNA sequence and analysis of human chromosome 9.	REXO4 SPATA31A1 SPATA31A7 TAL2 QSOX2 SLC27A4	3.00e-04	370	85	6	15164053
Pubmed	AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase.	AGAP5 AGAP9	3.20e-04	11	85	2	15381706
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	AGAP5 CCT5 KIF26A EHMT1 AGAP9 IQCE MGRN1	3.21e-04	529	85	7	14621295
Pubmed	Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.	ZC3H13 SH3KBP1 OTUD4 AFDN	3.26e-04	133	85	4	15144186
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	BNC2 AGAP5 VPS13D WDFY3 AGAP9 CAMTA1 NIPBL	3.48e-04	536	85	7	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	BNC2 AGAP5 VPS13D WDFY3 AGAP9 CAMTA1 NIPBL	3.55e-04	538	85	7	10512203
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	CCDC125 SMG8 PACRGL CCT5 OTUD5 CHD1 FAM186B NIPBL LIN28A QSOX2 MICU1	3.84e-04	1327	85	11	32694731
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	EEF1G REXO4 ZC3H13 SCN8A ADAMTS15 USP39 FAM186B IQCE	4.45e-04	736	85	8	29676528
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	SMG8 EEF1G REXO4 ABCF1 CCT5 AFDN CHD1 WDFY3 NIPBL SLC27A4 POLR3A	4.52e-04	1353	85	11	29467282
Pubmed	Differential interactions of Id proteins with basic-helix-loop-helix transcription factors.	TAL1 TAL2	4.52e-04	13	85	2	9242638
Pubmed	The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor Dysbindin.	AGAP5 AGAP9	4.52e-04	13	85	2	27713690
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	USP8 EEF1G ABCF1 ATF7IP ZMYND8 CAST CHD1 NIPBL AFF4	4.65e-04	934	85	9	33916271
Pubmed	Functional Proteomic Analysis of Repressive Histone Methyltransferase Complexes Reveals ZNF518B as a G9A Regulator.	ATF7IP EHMT1 LIN28A	5.03e-04	63	85	3	25680957
Pubmed	GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.	AGAP5 AGAP9	5.27e-04	14	85	2	22453919
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	N4BP2 ATF7IP SH3KBP1 EHMT1 OTUD4 AFDN WDFY3 NIPBL AFF4	5.79e-04	963	85	9	28671696
Pubmed	Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex.	ABCF1 SPATA31A7 OTUD4 AFF4	5.95e-04	156	85	4	22952844
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ABCF1 OTUD5 ZC3H13 ZMYND8 CAST OTUD4 AFDN NIPBL	6.18e-04	774	85	8	15302935
Pubmed	A yeast two-hybrid screen reveals that osteopontin associates with MAP1A and MAP1B in addition to other proteins linked to microtubule stability, apoptosis and protein degradation in the human brain.	USP8 CHD1 AFF4	6.30e-04	68	85	3	22779921
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	EEF1G REXO4 AFF2 CCT5 ATF7IP EHMT1 AFDN IQCE	6.34e-04	777	85	8	35844135
Pubmed	Hairy/Enhancer-of-Split MEGANE and Proneural MASH1 Factors Cooperate Synergistically in Midbrain GABAergic Neurogenesis.	TAL1 TAL2	6.93e-04	16	85	2	25993409
Pubmed	Human transcription factor protein interaction networks.	REXO4 CCT5 ATF7IP SH3KBP1 ZMYND8 EHMT1 OTUD4 MLLT6 TAL1 TAL2 NIPBL	7.12e-04	1429	85	11	35140242
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	USP8 EHMT1 OTUD4 WDFY3 USP39 TRDN NIPBL	9.70e-04	638	85	7	31182584
Pubmed	OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis.	OTUD5 OTUD4	9.83e-04	19	85	2	23827681
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SMG8 ABCF1 AFDN QSOX2 SLC27A4 POLR3A MGRN1	1.08e-03	650	85	7	38777146
Pubmed	Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.	EEF1G CCT5	1.09e-03	20	85	2	16548883
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	REXO4 ABCF1 CCT5 ZC3H13 AFDN CHD1 NIPBL	1.11e-03	653	85	7	22586326
Pubmed	Ascl1 and Helt act combinatorially to specify thalamic neuronal identity by repressing Dlxs activation.	TAL1 TAL2	1.20e-03	21	85	2	25512300
Pubmed	The role of Tal2 and Tal1 in the differentiation of midbrain GABAergic neuron precursors.	TAL1 TAL2	1.20e-03	21	85	2	24167708
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	AFF2 SH3KBP1 CAST MYO18B TAL1	1.30e-03	329	85	5	17474147
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	EEF1G REXO4 ABCF1 ZC3H13 ZMYND8 EHMT1 USP39 NIPBL AFF4	1.31e-03	1082	85	9	38697112
Pubmed	Infertility with defective spermiogenesis in mice lacking AF5q31, the target of chromosomal translocation in human infant leukemia.	AFF2 AFF4	1.32e-03	22	85	2	16024815
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	VPS13D ABCF1 CCT5 ZMYND8 CCDC187 USP39	1.39e-03	497	85	6	36774506
Pubmed	Gata2, Nkx2-2 and Skor2 form a transcription factor network regulating development of a midbrain GABAergic neuron subtype with characteristics of REM-sleep regulatory neurons.	TAL1 TAL2	1.44e-03	23	85	2	35815619
Pubmed	Hereditary Ataxia Overview	VPS13D FGF14 POLR3A	1.51e-03	92	85	3	20301317
Pubmed	USP37 is a SNAI1 deubiquitinase.	OTUD4 USP39	1.57e-03	24	85	2	31911859
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	AGAP5 SETMAR CCT5 AP3B2 OTUD4 FAM186B	1.64e-03	513	85	6	25798074
Pubmed	Differentiation and molecular heterogeneity of inhibitory and excitatory neurons associated with midbrain dopaminergic nuclei.	TAL1 TAL2	1.71e-03	25	85	2	26718003
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	EEF1G CCT5 OTUD5 ATF7IP ZC3H13 SH3KBP1 EHMT1 MAP3K21	1.89e-03	922	85	8	27609421
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	COCH ZC3H13 USP39 MYO18B MAP3K21	1.95e-03	361	85	5	26167880
Pubmed	Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs.	EEF1G CCT5 OTUD4	1.98e-03	101	85	3	19167051
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	ABCF1 ZMYND8 CHD1 USP39 NIPBL POLR3A	1.98e-03	533	85	6	30554943
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	EEF1G CCT5 CAST OTUD4 CHD1 MYO18B	2.08e-03	538	85	6	28524877
Pubmed	Dbx1 is a dorsal midbrain-specific determinant of GABAergic neuron fate and regulates differentiation of the dorsal midbrain into the inferior and superior colliculi.	TAL1 TAL2	2.14e-03	28	85	2	38344749
Pubmed	Transcriptional regulatory mechanisms underlying the GABAergic neuron fate in different diencephalic prosomeres.	TAL1 TAL2	2.30e-03	29	85	2	22991444
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	EEF1G ABCF1 CCT5 N4BP2 ZC3H13 OTUD4	2.34e-03	551	85	6	34728620
Cytoband	Ensembl 112 genes in cytogenetic band chr9q12	SPATA31A7 SPATA31A5	9.42e-05	8	85	2	chr9q12
Cytoband	Ensembl 112 genes in cytogenetic band chr9q34	REXO4 EHMT1 CCDC187 QSOX2 SLC27A4	3.56e-04	325	85	5	chr9q34
Cytoband	13q14.13	LRRC63 ZC3H13	8.36e-04	23	85	2	13q14.13
GeneFamily	AF4/FMR2 family\|Super elongation complex	AFF2 AFF4	4.13e-05	4	48	2	1145
GeneFamily	AF4/FMR2 family\|Super elongation complex	AFF2 AFF4	2.46e-04	9	48	2	1280
GeneFamily	OTU domain containing	OTUD5 OTUD4	9.15e-04	17	48	2	669
GeneFamily	X-linked mental retardation\|Rho GTPase activating proteins\|BAR-PH domain containing	AGAP5 AGAP9	9.15e-04	17	48	2	1291
GeneFamily	ArfGAPs	AGAP5 AGAP9	3.46e-03	33	48	2	395
GeneFamily	Ubiquitin specific peptidases	USP8 USP39	9.70e-03	56	48	2	366
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	FSIP2 ZNF385D AFF2 N4BP2 SLC16A14 AP3B2 SH3KBP1 ZMYND8 SCN8A OTUD4 FGF14 CAMTA1 TAL1 SEZ6L	1.05e-05	1106	84	14	M39071
ToppCell	droplet-Spleen-nan-18m-Myeloid-granulocyte\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC125 PKNOX2 MCTP1 AFF2 LIN28A	1.52e-05	163	85	5	bc37c5d9f48b16096d5313657563f3ec84028c8c
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Basal_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	ZNF385D ZBTB32 LARP6 ADAMTS15 SEZ6L	1.52e-05	163	85	5	f21951e63188eb0c04675a8f81a0da495c26c007
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	AP3B2 SCN8A FGF14 ST18 SEZ6L	1.57e-05	164	85	5	be49af6335f2505065cde2cb9800e4a5516811b1
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AP3B2 SCN8A ST18 SEZ6L POLR3A	2.26e-05	177	85	5	8abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BNIP5 AFF2 PER3 CEP41 FGF14	2.45e-05	180	85	5	8bf6e8b6b45ce42f8c5f23e7cd1752ec8b3fa2d2
ToppCell	Epithelial-lung_neuroendocrine_cell_(PNEC)\|World / Lineage, Cell type, age group and donor	AP3B2 SCN8A FGF14 ST18 SEZ6L	2.59e-05	182	85	5	57bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-I_cells_(CCK+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FGF14 ASIC5 TAL2 ST18 SEZ6L	2.73e-05	184	85	5	1e6f86f9e379cd9f453f6b7185f681b44eb63e09
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	AP3B2 SCN8A FGF14 ST18 SEZ6L	2.87e-05	186	85	5	b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	AP3B2 SCN8A FGF14 ST18 SEZ6L	3.02e-05	188	85	5	c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BNIP5 PER3 FGF14 ST18 SEZ6L	3.10e-05	189	85	5	fcc3713e8200d51074f709f3360fb36efb0a639f
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PKNOX2 OLFML2A AFF2 SH3KBP1 CAST	3.18e-05	190	85	5	10125091ad648163777b02e9f0d5e8d7f17d44a5
ToppCell	IPF-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	ZNF385D BNC2 MCTP1 OTUD4 CHD1	3.87e-05	198	85	5	b8bd1ba268480f54451648e01631b615a3401144
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	VPS13D ZC3H13 CHD1 NIPBL TGS1	3.87e-05	198	85	5	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ATF7IP CAST CHD1 NIPBL AFF4	4.06e-05	200	85	5	12f1685ce8f218433068e090c9d839cd5a1910bf
Computational	Genes in the cancer module 67.	ZNF385D KIAA1210 VPS13D ZBTB32 CES3 MAP3K21	1.12e-04	227	37	6	MODULE_67
Disease	mean fractional anisotropy measurement	ZBTB32 COCH WDFY3 CAMTA1	1.39e-04	95	81	4	EFO_0008399
Disease	Acute lymphoid leukemia	TAL1 TAL2	2.06e-04	8	81	2	cv:C0023449
Disease	LEUKEMIA, ACUTE LYMPHOBLASTIC	TAL1 TAL2	2.06e-04	8	81	2	613065
Disease	cerebral palsy (implicated_via_orthology)	AGAP5 AGAP9	3.30e-04	10	81	2	DOID:1969 (implicated_via_orthology)
Disease	response to radiation, Urinary retention	ZNF385D CAMTA1	9.85e-04	17	81	2	GO_0009314, HP_0000016
Disease	response to alcohol	ZNF385D CAST AFDN	1.17e-03	75	81	3	EFO_0005526
Disease	Nystagmus	AFF2 FGF14	1.51e-03	21	81	2	HP_0000639
Disease	susceptibility to plantar warts measurement	N4BP2 FGF14 CAMTA1	1.97e-03	90	81	3	EFO_0008406
Disease	Bone Diseases, Developmental	NIPBL AFF4	2.50e-03	27	81	2	C0005941

Protein segments in the cluster

Peptide	Gene	Start	Entry
HKDRAAGKPPKPKYS	ZNF385D	291	Q9H6B1
RPPDHIPKKTKKHLE	AFDN	346	P55196
EEKHPPKPAKPEKNR	ABCF1	146	Q8NE71
ERLKQKHKKRPESPP	MLLT6	246	P55198
SHKDYPAPKKHKLNP	CAMTA1	1236	Q9Y6Y1
PKLPSPRRAAKDKHK	CCDC187	261	A0A096LP49
PPPSPHANKKKHLKK	AGAP9	436	Q5VTM2
HEPSADLAPKKKPRK	BNC2	621	Q6ZN30
KPAPKGKRKHKPIEV	AFF2	846	P51816
LETPGKLPSHPKKKS	FBXW10	791	Q5XX13
VKKAEPHTKDKPYPD	CEP41	156	Q9BYV8
KPKKCKLPAASPRHI	FAM186B	806	Q8IYM0
KLALKHHPDKNPDDP	DNAJC5B	41	Q9UF47
HKILPDDPDKKPQAK	CHD1	1286	O14646
PKEPREDKSSHPKDP	ADAMTS15	801	Q8TE58
PPKGEKKNVPEKHTR	AFF4	736	Q9UHB7
EAPPTKKPLILKRKH	CCNB3	481	Q8WWL7
SRHAKKLFLAPKPAP	AP3B2	596	Q13367
GKKHTSKNLKAPPPE	OTUD4	321	Q01804
DVRKKSLPLPEKPHK	QSOX2	291	Q6ZRP7
VETKAKRKAFHKPPP	IQCE	26	Q6IPM2
KRKAFHKPPPTSPKS	IQCE	31	Q6IPM2
ELKPDPSHSPYKRKK	MCTP1	981	Q6DN14
PEPKKDDAKAAPKAA	MYL3	6	P08590
PLPHKHERKDKRSTP	LINC02693	146	A8MQB3
SKPHPASLASKKPKR	MGRN1	361	O60291
SPKDNPKPCFKAHLK	FSIP2	2651	Q5CZC0
DLAPHPEEKKKKRSG	MICU1	91	Q9BPX6
KGKHKRKKLPEPPDS	PER3	736	P56645
RVKKTKPAAHFLPKP	FGF14	186	Q92915
HPETPKKKSDPELSK	NIPBL	596	Q6KC79
PKKKPAKDKNHDEEP	LARP6	296	Q9BRS8
QKLSLASKRKKPHPP	KIF26A	311	Q9ULI4
PLPPKFTKLSLHEKK	LRRC63	11	Q05C16
EPALRKKAHHDKKPS	BNIP5	141	P0C671
KHLKEDGFPSPRSKK	CCDC125	361	Q86Z20
KPLPSPTERKKFDHD	ASIC5	26	Q9NY37
KPKEHTEPKSLPKQA	CAST	56	P20810
AKEDLKKRHEHPPNP	ATF7IP	656	Q6VMQ6
DESPKNPQKKALPHK	KIAA1210	336	Q9ULL0
AAEPKAKDPFAHLPK	EEF1G	271	P26641
KELHITKPKTPPKDG	FBXO16	161	Q8IX29
FPKSPKELLKEKPFH	CES3	321	Q6UWW8
AHPPTGKRLKKTPEK	COCH	141	O43405
SEKAKPSPHPIKDKL	ZMYND8	676	Q9ULU4
PSPHPIKDKLKGKDE	ZMYND8	681	Q9ULU4
ALDSEKPKKLRFHPK	EHMT1	726	Q9H9B1
PDPAPKAKKIKSQHR	PKNOX2	356	Q96KN3
SMKKNKVHRDPPPDK	OTUD5	556	Q96G74
KSFADRGLPKPPKEK	OLFML2A	241	Q68BL7
ARKLHPRPSDKLNPK	PACRGL	51	Q8N7B6
AHPDKPKKHSPKRRL	SMG8	286	Q8ND04
HKKRKAKEAAPAPPT	REXO4	176	Q9GZR2
EARPKHALPPKKKLP	SEZ6L	106	Q9BYH1
FTKKLPHPDLPAEEK	USP39	356	Q53GS9
KPEHRQSKVEKKHLP	LIAT1	131	Q6ZQX7
EPKLSPDGLEHRKPK	MAP3K21	646	Q5TCX8
PKDKKTLKPHPNIDG	SLC16A14	16	Q7RTX9
RKLIPTHPPDKKLSK	TAL1	211	P17542
PIHKSEKSRKPNLEK	SPATA31A7	1106	Q8IWB4
KKDPLTNKAPEKPLH	SH3KBP1	61	Q96B97
KLLHKADRDPNPPKR	POLR3A	1361	O14802
EAPKHFPKPILHPKK	SETMAR	516	Q53H47
EPPKPKTKHKLDVTS	CCT5	256	P48643
DSKKTKKHPPPVETK	CCT8L2	536	Q96SF2
PSPKPKLHARDLKKE	ST18	706	O60284
PPPSPHANKKKHLKK	AGAP5	391	A6NIR3
KKEREALGDKAPPKP	RPF1	86	Q9H9Y2
KQLFKKPHPPKRVRS	WDFY3	2966	Q8IZQ1
PIHKSEKSRKPNLEK	SPATA31A1	1106	Q5TZJ5
PIHKSEKSRKPNLEK	SPATA31A5	1106	Q5VU36
LLKDAPKHLPSCPDK	SLC27A4	221	Q6P1M0
IHLLEPPRKKAPRSK	ZSCAN1	341	Q8NBB4
ESKLKKPPKADGSHR	SCN8A	31	Q9UQD0
RKLIPTHPPDKKLSK	TAL2	26	Q16559
ILKKSPEPKEDPAHL	MYO18B	2491	Q8IUG5
PAKSPKKEHSVPSDK	TRDN	406	Q13061
RAKKPDPGLKKHQEE	ZBTB32	116	Q9Y2Y4
PPEHKPSKLKRSHEL	TGS1	416	Q96RS0
PPKLVNDKPHKFKDH	STAC3	81	Q96MF2
KKPAVKLPEEHRIKS	USP8	411	P40818
KPHKKKSPGEKPHRC	ZNF449	311	Q6P9G9
KHPKEPREPGAALLK	ZC3H13	1506	Q5T200
HPPRLKLEAKAKPRL	VPS13D	2786	Q5THJ4
RKKPAEKKSHSDPRP	GARIN5B	246	Q8N5Q1
DHHAKECKLPPQPKK	LIN28A	146	Q9H9Z2
FKPHKHPELPTKGKD	N4BP2	326	Q86UW6