Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	multi-pass transmembrane protein insertion into ER membrane	NOMO1 NOMO2 NOMO3	1.42e-05	9	116	3	GO:0160063
GeneOntologyCellularComponent	multi-pass translocon complex	NOMO1 NOMO2 NOMO3	1.37e-05	9	116	3	GO:0160064
GeneOntologyCellularComponent	ER membrane insertion complex	NOMO1 NOMO2 NOMO3	5.80e-05	14	116	3	GO:0072379
Domain	DUF2012	NOMO1 NOMO2 NOMO3	9.30e-07	4	116	3	PF09430
Domain	DUF2012	NOMO1 NOMO2 NOMO3	9.30e-07	4	116	3	IPR019008
Domain	Liprin	PPFIA4 PPFIA1 PPFIA3	4.61e-06	6	116	3	IPR029515
Domain	Carb-bd-like_fold	NOMO1 NOMO2 NOMO3	1.28e-05	8	116	3	IPR013784
Domain	CarboxyPept_regulatory_dom	NOMO1 NOMO2 NOMO3	6.38e-05	13	116	3	IPR014766
Domain	-	NOMO1 NOMO2 NOMO3	6.38e-05	13	116	3	2.60.40.1120
Domain	SAM_1	PPFIA4 PPFIA1 PPFIA3 ANKS4B GAREM1	6.47e-05	68	116	5	PF00536
Domain	CarboxyPept-like_regulatory	NOMO1 NOMO2 NOMO3	1.49e-04	17	116	3	IPR008969
Domain	SAM_DOMAIN	PPFIA4 PPFIA1 PPFIA3 ANKS4B GAREM1	3.15e-04	95	116	5	PS50105
Domain	SAM	PPFIA4 PPFIA1 PPFIA3 ANKS4B GAREM1	3.47e-04	97	116	5	IPR001660
Domain	Pyr_OxRdtase_I_AS	GSR DLD	3.78e-04	5	116	2	IPR012999
Domain	Pyr_redox_dim	GSR DLD	3.78e-04	5	116	2	PF02852
Domain	PYRIDINE_REDOX_1	GSR DLD	3.78e-04	5	116	2	PS00076
Domain	Prot_inh_Kazal-m	SPINK9 SPINK6	3.78e-04	5	116	2	IPR001239
Domain	Adcy_conserved_dom	ADCY2 ADCY7	5.64e-04	6	116	2	IPR009398
Domain	DUF1053	ADCY2 ADCY7	5.64e-04	6	116	2	PF06327
Domain	-	GSR DLD	7.87e-04	7	116	2	3.30.390.30
Domain	SAM/pointed	PPFIA4 PPFIA1 PPFIA3 ANKS4B GAREM1	8.17e-04	117	116	5	IPR013761
Domain	Pyr_nucl-diS_OxRdtase_dimer	GSR DLD	1.04e-03	8	116	2	IPR004099
Domain	FAD/NAD-linked_Rdtase_dimer	GSR DLD	1.04e-03	8	116	2	IPR016156
Domain	AC_N	ADCY2 ADCY7	1.04e-03	8	116	2	IPR032628
Domain	Adcy	ADCY2 ADCY7	1.04e-03	8	116	2	IPR030672
Domain	AC_N	ADCY2 ADCY7	1.04e-03	8	116	2	PF16214
Domain	Plexin_cytopl	PLXNA4 PLXNA2	1.34e-03	9	116	2	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXNA4 PLXNA2	1.34e-03	9	116	2	IPR013548
Domain	Plexin	PLXNA4 PLXNA2	1.34e-03	9	116	2	IPR031148
Domain	Q_MOTIF	DDX46 DDX54 DDX39A	1.56e-03	37	116	3	PS51195
Domain	RNA_helicase_DEAD_Q_motif	DDX46 DDX54 DDX39A	1.56e-03	37	116	3	IPR014014
Domain	Rap_GAP	SIPA1L3 TSC2	1.67e-03	10	116	2	PF02145
Domain	Rap_GAP_dom	SIPA1L3 TSC2	2.03e-03	11	116	2	IPR000331
Domain	RAPGAP	SIPA1L3 TSC2	2.03e-03	11	116	2	PS50085
Domain	Rho_GTPase_activation_prot	TAGAP ARHGAP36 PLXNA4 PLXNA2	2.21e-03	88	116	4	IPR008936
Domain	SAM	PPFIA4 PPFIA1 PPFIA3 ANKS4B	2.21e-03	88	116	4	SM00454
Domain	SAM_2	PPFIA4 PPFIA1 PPFIA3	2.40e-03	43	116	3	PF07647
Domain	-	HYOU1 HSPA4	2.42e-03	12	116	2	2.60.34.10
Domain	HSP70_peptide-bd	HYOU1 HSPA4	2.42e-03	12	116	2	IPR029047
Domain	-	HYOU1 HSPA4	2.85e-03	13	116	2	1.20.1270.10
Domain	Heat_shock_70_CS	HYOU1 HSPA4	2.85e-03	13	116	2	IPR018181
Domain	HSP70_C	HYOU1 HSPA4	2.85e-03	13	116	2	IPR029048
Domain	Linker_histone	H1-9P H1-1	2.85e-03	13	116	2	PF00538
Domain	Histone_H1/H5_H15	H1-9P H1-1	3.31e-03	14	116	2	IPR005818
Domain	Ig_E-set	TRIM2 LY96 PLXNA4 PLXNA2	4.03e-03	104	116	4	IPR014756
Domain	-	PPFIA4 PPFIA1 PPFIA3 ANKS4B	4.31e-03	106	116	4	1.10.150.50
Domain	AT_hook	MECP2 KMT2A	4.34e-03	16	116	2	PF02178
Domain	HSP70	HYOU1 HSPA4	4.34e-03	16	116	2	PF00012
Domain	Ig-like_fold	TRIM2 OBSCN NOMO1 LRRN3 CD4 NOMO2 IGHG4 PLXNA4 ROS1 PLXNA2 NOMO3	4.49e-03	706	116	11	IPR013783
Domain	HSP70_2	HYOU1 HSPA4	4.89e-03	17	116	2	PS00329
Domain	A/G_cyclase_CS	ADCY2 ADCY7	4.89e-03	17	116	2	IPR018297
Domain	HSP70_1	HYOU1 HSPA4	4.89e-03	17	116	2	PS00297
Domain	HSP70_3	HYOU1 HSPA4	4.89e-03	17	116	2	PS01036
Domain	KAZAL_1	SPINK9 SPINK6	5.48e-03	18	116	2	PS00282
Domain	-	ADCY2 ADCY7	5.48e-03	18	116	2	3.30.70.1230
Domain	Nucleotide_cyclase	ADCY2 ADCY7	5.48e-03	18	116	2	IPR029787
Domain	Hsp_70_fam	HYOU1 HSPA4	5.48e-03	18	116	2	IPR013126
Domain	Guanylate_cyc	ADCY2 ADCY7	6.10e-03	19	116	2	PF00211
Domain	GUANYLATE_CYCLASE_2	ADCY2 ADCY7	6.10e-03	19	116	2	PS50125
Domain	A/G_cyclase	ADCY2 ADCY7	6.10e-03	19	116	2	IPR001054
Domain	GUANYLATE_CYCLASE_1	ADCY2 ADCY7	6.10e-03	19	116	2	PS00452
Domain	CYCc	ADCY2 ADCY7	6.10e-03	19	116	2	SM00044
Domain	Pyr_redox_2	GSR DLD	6.10e-03	19	116	2	PF07992
Pathway	REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE	PPFIA4 PPFIA1 PPFIA3	1.45e-04	17	87	3	M93
Pathway	REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE	PPFIA4 PPFIA1 PPFIA3	1.45e-04	17	87	3	MM14907
Pathway	REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE	PPFIA4 PPFIA1 PPFIA3	1.73e-04	18	87	3	M13015
Pathway	REACTOME_SEROTONIN_NEUROTRANSMITTER_RELEASE_CYCLE	PPFIA4 PPFIA1 PPFIA3	1.73e-04	18	87	3	MM14702
Pathway	REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE	PPFIA4 PPFIA1 PPFIA3	1.73e-04	18	87	3	MM14703
Pathway	REACTOME_SEROTONIN_NEUROTRANSMITTER_RELEASE_CYCLE	PPFIA4 PPFIA1 PPFIA3	1.73e-04	18	87	3	M27043
Pathway	REACTOME_RECEPTOR_TYPE_TYROSINE_PROTEIN_PHOSPHATASES	PPFIA4 PPFIA1 PPFIA3	2.40e-04	20	87	3	M27290
Pathway	REACTOME_RECEPTOR_TYPE_TYROSINE_PROTEIN_PHOSPHATASES	PPFIA4 PPFIA1 PPFIA3	2.40e-04	20	87	3	MM14991
Pathway	REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE	PPFIA4 PPFIA1 PPFIA3	3.68e-04	23	87	3	MM14852
Pathway	REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE	PPFIA4 PPFIA1 PPFIA3	3.68e-04	23	87	3	M12627
Pathway	REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE	PPFIA4 PPFIA1 PPFIA3	4.18e-04	24	87	3	MM14834
Pathway	REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE	PPFIA4 PPFIA1 PPFIA3	4.18e-04	24	87	3	M630
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	NOLC1 HYOU1 ACADVL CTDSPL2 PPFIA4 PPFIA1 SIPA1L3 CNTRL XPC MECP2 GSR CDK13 N4BP2 SAP30BP PLXNA4 KMT2A DLD H1-1 MPHOSPH10 PLCH1 DTHD1 DDX39A DNAH8 PLXNA2	1.31e-10	1442	120	24	35575683
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	RARS1 SCAF8 PPFIA1 SIPA1L3 CKAP5 FAM76B SRP68 RRP8 XPC MECP2 KIF20B NOMO1 PTPN13 DDX46 AFAP1 CDK13 SAP30BP TPX2 KMT2A DNAJC1 MPHOSPH10 CTNND2 VDAC2	1.57e-09	1497	120	23	31527615
Pubmed	Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice.	PPFIA4 PPFIA1 PPFIA3 NOMO1 NOMO2 CTNND2 HSPA4 NOMO3	4.84e-09	110	120	8	27889896
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	NOLC1 DNAJC13 HYOU1 ACADVL TEX2 DCTN2 POLE PPFIA1 RRP8 GSR NOMO1 USP31 PTPN13 NCAPG NOMO2 N4BP2 DDX54 DLD DNAJC1 PLCH1 HSPA4	3.79e-08	1487	120	21	33957083
Pubmed	Recurrent NOMO1 Gene Deletion Is a Potential Clinical Marker in Early-Onset Colorectal Cancer and Is Involved in the Regulation of Cell Migration.	NOMO1 NOMO2 NOMO3	4.01e-08	3	120	3	36011023
Pubmed	Silencing of nodal modulator 1 inhibits the differentiation of P19 cells into cardiomyocytes.	NOMO1 NOMO2 NOMO3	4.01e-08	3	120	3	25576386
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	NOLC1 DNAJC13 POLE CKAP5 SRP68 RRP8 KIF20B DDX46 PRPF4 CDK13 TPX2 DDX54 DLD MPHOSPH10 DDX39A	6.00e-08	759	120	15	35915203
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	TANC2 DNAJC13 HYOU1 DCTN2 PPFIA4 PPFIA1 SIPA1L3 CKAP5 SRP68 PPFIA3 MECP2 USP31 AFAP1 PLXNA4 KMT2A DLD CTNND2 PLCH1 HSPA4 VDAC2	9.87e-08	1431	120	20	37142655
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	TANC2 NOLC1 DNAJC13 DCTN2 SCAF8 POLE PPFIA1 CKAP5 SRP68 NCAPG DDX46 TPX2 DDX39A	1.21e-07	582	120	13	20467437
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	NOLC1 HYOU1 RARS1 ACADVL SCAF8 SRP68 AK6 NCAPG DDX46 PRPF4 SAP30BP DDX54 KMT2A DLD TXNDC9 MPHOSPH10 DDX39A HSPA4 VDAC2	1.33e-07	1318	120	19	30463901
Pubmed	Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology.	NOMO1 NOMO2 NOMO3	1.60e-07	4	120	3	31833031
Pubmed	A locus for autosomal recessive pseudoxanthoma elasticum, with penetrance of vascular symptoms in carriers, maps to chromosome 16p13.1.	NOMO1 NOMO2 NOMO3	1.60e-07	4	120	3	9267806
Pubmed	The mouse and human Liprin-alpha family of scaffolding proteins: genomic organization, expression profiling and regulation by alternative splicing.	PPFIA4 PPFIA1 PPFIA3	3.99e-07	5	120	3	19013515
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	NOLC1 HYOU1 POLE CKAP5 SRP68 RRP8 DDX46 DDX54 KMT2A DLD H1-1 MPHOSPH10 HSPA4	4.46e-07	653	120	13	22586326
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	NOLC1 PEX1 PCGF5 NOMO1 SGK3 CD4 NOMO2 CDK13 SAP30BP TPX2 KMT2A AKT1 PDE7B HSPA4 NOMO3	6.06e-07	910	120	15	36736316
Pubmed	Analyses of the spatiotemporal expression and subcellular localization of liprin-α proteins.	PPFIA4 PPFIA1 PPFIA3	7.95e-07	6	120	3	21618221
Pubmed	Protein kinase B alpha/Akt1 regulates placental development and fetal growth.	TSC2 AKT1 NOS3	7.95e-07	6	120	3	12783884
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	NOLC1 FAM76B AK6 RRP8 ZDBF2 MECP2 KIF20B DDX46 PRPF4 SAP30BP TPX2 KMT2A MPHOSPH10 QSER1 VDAC2	1.09e-06	954	120	15	36373674
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	NOLC1 HYOU1 RARS1 SIPA1L3 CKAP5 LAMA3 SRP68 RRP8 MECP2 KIF20B AFAP1 PRPF4 SAP30BP TPX2 DDX54 MPHOSPH10 VDAC2	1.56e-06	1257	120	17	36526897
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	HYOU1 TEX2 SCAF8 PPFIA1 SRP68 ZDBF2 ZNF106 NOMO2 N4BP2 TPX2 DNAJC1 QSER1 PLCH1	1.61e-06	733	120	13	34672954
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	XPC MECP2 KIF20B ZNF106 CDK13 TPX2 DDX54 MPHOSPH10 QSER1 VDAC2	1.70e-06	410	120	10	26949251
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	TANC2 NOLC1 TEX2 PPFIA1 SIPA1L3 CKAP5 TSC2 USP31 ZNF106 PTPN13 N4BP2 KMT2A FNIP1 PLCH1	1.73e-06	861	120	14	36931259
Pubmed	Nicalin and its binding partner Nomo are novel Nodal signaling antagonists.	NOMO1 NOMO2 NOMO3	2.22e-06	8	120	3	15257293
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	NOLC1 CTDSPL2 CKAP5 RRP8 XPC MECP2 ZNF106 DDX46 PRPF4 CDK13 SAP30BP TPX2 DDX54 KMT2A ELF4 DNAJC1 QSER1	2.31e-06	1294	120	17	30804502
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	NOLC1 DNAJC13 UBE4B SCAF8 CKAP5 FAM76B XPC MECP2 ZNF106 DDX46 CDK13 TPX2 KMT2A	2.93e-06	774	120	13	15302935
Pubmed	Substrate-driven assembly of a translocon for multipass membrane proteins.	NOMO1 NOMO2 NOMO3	3.31e-06	9	120	3	36261522
Pubmed	Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins.	PPFIA4 PPFIA1 PPFIA3	3.31e-06	9	120	3	12923177
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	RARS1 DCTN2 SRP68 PTPN13 NCAPG DDX46 SAP30BP TPX2 KMT2A QSER1 VDAC2	3.38e-06	549	120	11	38280479
Pubmed	The synaptic vesicle cycle.	PPFIA4 PPFIA1 PPFIA3 UNC13C	3.95e-06	31	120	4	15217342
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	NOLC1 HYOU1 TAGAP FBXW12 TEX2 CYP17A1 PPFIA1 CNTRL OBSCN PEX1 FAM76B PTPN13 MPHOSPH10 QSER1 DDX39A	5.16e-06	1084	120	15	11544199
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	NOLC1 HYOU1 RARS1 CKAP5 FAM76B SRP68 AK6 MECP2 PRPF4 CDK13 TPX2 KMT2A QSER1 DDX39A HSPA4	6.36e-06	1103	120	15	34189442
Pubmed	An ER translocon for multi-pass membrane protein biogenesis.	NOMO1 NOMO2 NOMO3	6.48e-06	11	120	3	32820719
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	TEX2 PPFIA1 SIPA1L3 ZDBF2 PTPN13 AFAP1 FNIP1	8.57e-06	209	120	7	36779422
Pubmed	Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins.	PPFIA4 PPFIA1 PPFIA3	8.61e-06	12	120	3	9624153
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	RASGRF2 PPFIA1 OBSCN RRP8 ZNF106 DDX46 LOXHD1 SAP30BP DDX54 KMT2A	9.27e-06	497	120	10	36774506
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	NOLC1 DCTN2 PEX1 KIF20B WASH6P DDX46 PRPF4 CDK13 SAP30BP TPX2	1.08e-05	506	120	10	30890647
Pubmed	Endothelial nitric oxide synthase is involved in calcium-induced Akt signaling in mouse skeletal muscle.	AKT1 NOS3	1.18e-05	2	120	2	19682597
Pubmed	The mitochondrial redistribution of ENOS is regulated by AKT1 and dimer status.	AKT1 NOS3	1.18e-05	2	120	2	39332480
Pubmed	Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway.	TSC2 AKT1	1.18e-05	2	120	2	12150915
Pubmed	Protective effect of 17beta-estradiol on ischemic acute renal failure through the PI3K/Akt/eNOS pathway.	AKT1 NOS3	1.18e-05	2	120	2	18004295
Pubmed	Asymmetric dimethylarginine induces endothelial nitric-oxide synthase mitochondrial redistribution through the nitration-mediated activation of Akt1.	AKT1 NOS3	1.18e-05	2	120	2	23255608
Pubmed	Regulation of arterial blood pressure by Akt1-dependent vascular relaxation.	AKT1 NOS3	1.18e-05	2	120	2	21842346
Pubmed	Voltage-dependent anion channel-2 interaction with nitric oxide synthase enhances pulmonary artery endothelial cell nitric oxide production.	NOS3 VDAC2	1.18e-05	2	120	2	22842492
Pubmed	Mechanism of Akt1 inhibition of breast cancer cell invasion reveals a protumorigenic role for TSC2.	TSC2 AKT1	1.18e-05	2	120	2	16537497
Pubmed	Rad4 regulates protein turnover at a postubiquitylation step.	UBE4B XPC	1.18e-05	2	120	2	19889839
Pubmed	Phosphorylation of Akt at Thr308 regulates p-eNOS Ser1177 during physiological conditions.	AKT1 NOS3	1.18e-05	2	120	2	33993653
Pubmed	PTPN13 acts as a tumor suppressor in clear cell renal cell carcinoma by inactivating Akt signaling.	PTPN13 AKT1	1.18e-05	2	120	2	32919955
Pubmed	The phosphatidylinositol 3-kinase/akt cassette regulates purine nucleotide synthesis.	TSC2 AKT1	1.18e-05	2	120	2	19068483
Pubmed	Osteocalcin attenuates high fat diet-induced impairment of endothelium-dependent relaxation through Akt/eNOS-dependent pathway.	AKT1 NOS3	1.18e-05	2	120	2	24708830
Pubmed	Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation.	AKT1 NOS3	1.18e-05	2	120	2	10376603
Pubmed	Ceramide mediates inhibition of the AKT/eNOS signaling pathway by palmitate in human vascular endothelial cells.	AKT1 NOS3	1.18e-05	2	120	2	19721393
Pubmed	Endothelial microparticles increase in mitral valve disease and impair mitral valve endothelial function.	AKT1 NOS3	1.18e-05	2	120	2	23384770
Pubmed	Erythropoietin increases endothelial biosynthesis of tetrahydrobiopterin by activation of protein kinase B alpha/Akt1.	AKT1 NOS3	1.18e-05	2	120	2	18519842
Pubmed	Rapid nongenomic actions of thyroid hormone.	AKT1 NOS3	1.18e-05	2	120	2	16966610
Pubmed	The Akt1-eNOS axis illustrates the specificity of kinase-substrate relationships in vivo.	AKT1 NOS3	1.18e-05	2	120	2	19654415
Pubmed	Long-term swimming exercise does not modulate the Akt-dependent endothelial nitric oxide synthase phosphorylation in healthy mice.	AKT1 NOS3	1.18e-05	2	120	2	21186380
Pubmed	Rho GTPase/Rho kinase negatively regulates endothelial nitric oxide synthase phosphorylation through the inhibition of protein kinase B/Akt in human endothelial cells.	AKT1 NOS3	1.18e-05	2	120	2	12446767
Pubmed	Akt1 mediates purinergic-dependent NOS3 activation in thick ascending limbs.	AKT1 NOS3	1.18e-05	2	120	2	19570880
Pubmed	Renal tumours in a Tsc2(+/-) mouse model do not show feedback inhibition of Akt and are effectively prevented by rapamycin.	TSC2 AKT1	1.18e-05	2	120	2	24632604
Pubmed	Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site.	AKT1 NOS3	1.18e-05	2	120	2	11696579
Pubmed	Effects of simulated microgravity on human umbilical vein endothelial cell angiogenesis and role of the PI3K-Akt-eNOS signal pathway.	AKT1 NOS3	1.18e-05	2	120	2	22808143
Pubmed	Gender dimorphism of the cardiac dysfunction in murine sepsis: signalling mechanisms and age-dependency.	AKT1 NOS3	1.18e-05	2	120	2	24945834
Pubmed	HSPA4 regulated glioma progression via activation of AKT signaling pathway.	AKT1 HSPA4	1.18e-05	2	120	2	37339521
Pubmed	Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage.	PPFIA1 OBSCN AFAP1 TPX2 DDX54 DDX39A	1.37e-05	149	120	6	25184681
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	TANC2 POLE SRP68 RRP8 ZDBF2 XPC PPFIA3 ADCY2 MPHOSPH10 CTNND2 NOMO3	1.39e-05	638	120	11	31182584
Pubmed	STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production.	DCTN2 SIPA1L3 OBSCN SRP68 DDX54 DTHD1 DDX39A HSPA4	1.48e-05	316	120	8	31665637
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	RNASEH2B DCTN2 CKAP5 SRP68 XPC MECP2 NCAPG TPX2 KMT2A TXNDC9 VDAC2	1.53e-05	645	120	11	25281560
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	NOLC1 HYOU1 ACADVL PLGRKT TEX2 POLE PEX1 TSC2 RRP8 ZDBF2 ZZEF1 CDK13 DDX54 TXNDC9 DNAJC1 MPHOSPH10 VDAC2	1.55e-05	1496	120	17	32877691
Pubmed	The sequence and analysis of duplication-rich human chromosome 16.	TSC2 NOMO1 WASH4P NOMO2 NOMO3	1.56e-05	90	120	5	15616553
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	NOLC1 DNAJC13 RARS1 UBE4B POLE CKAP5 SRP68 XPC KIF20B NCAPG DDX54 TXNDC9 H1-1 DDX39A HSPA4 VDAC2	1.74e-05	1353	120	16	29467282
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	NOLC1 DNAJC13 HYOU1 DCTN2 CKAP5 SRP68 AK6 NCAPG DDX46 SAP30BP DLD H1-1 DDX39A ALDH6A1 HSPA4 VDAC2	1.97e-05	1367	120	16	32687490
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	NOLC1 CKAP5 SRP68 GSR PTPN13 DDX46 SAP30BP TPX2 KMT2A DLD TXNDC9 HSPA4 VDAC2	2.16e-05	934	120	13	33916271
Pubmed	RNF12 catalyzes BRF1 ubiquitination and regulates RNA polymerase III-dependent transcription.	NOLC1 PPFIA1 PRPF4 HSPA4	2.75e-05	50	120	4	30413534
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	NOLC1 HYOU1 RARS1 ACADVL SCAF8 CKAP5 SRP68 TSC2 GSR NCAPG DDX46 PRPF4 CDK13 DDX54 HSPA4 VDAC2	2.99e-05	1415	120	16	28515276
Pubmed	Structural Basis for Plexin Activation and Regulation.	PLXNA4 PLXNA2	3.53e-05	3	120	2	27397516
Pubmed	Interactions between plexin-A2, plexin-A4, and semaphorin 6A control lamina-restricted projection of hippocampal mossy fibers.	PLXNA4 PLXNA2	3.53e-05	3	120	2	17296555
Pubmed	HDL induces NO-dependent vasorelaxation via the lysophospholipid receptor S1P3.	AKT1 NOS3	3.53e-05	3	120	2	14966566
Pubmed	βArrestin1 regulates the guanine nucleotide exchange factor RasGRF2 expression and the small GTPase Rac-mediated formation of membrane protrusion and cell motility.	RASGRF2 AKT1	3.53e-05	3	120	2	24692549
Pubmed	Positive feedback regulation of heat shock protein 70 (Hsp70) is mediated through Toll-like receptor 4-PI3K/Akt-glycogen synthase kinase-3β pathway.	AKT1 HSPA4	3.53e-05	3	120	2	23043959
Pubmed	Functional nitric oxide synthase mislocalization in cardiomyopathy.	SGCD NOS3	3.53e-05	3	120	2	14871549
Pubmed	Reduced AKT/mTOR signaling and protein synthesis dysregulation in a Rett syndrome animal model.	MECP2 AKT1	3.53e-05	3	120	2	21212100
Pubmed	CAIR-1/BAG-3 abrogates heat shock protein-70 chaperone complex-mediated protein degradation: accumulation of poly-ubiquitinated Hsp90 client proteins.	AKT1 HSPA4	3.53e-05	3	120	2	12750378
Pubmed	The protective effect of Bcl-xl overexpression against oxidative stress-induced vascular endothelial cell injury and the role of the Akt/eNOS pathway.	AKT1 NOS3	3.53e-05	3	120	2	24217227
Pubmed	Role of transmembrane semaphorin Sema6A in oligodendrocyte differentiation and myelination.	PLXNA4 PLXNA2	3.53e-05	3	120	2	22777942
Pubmed	Functional proteomic analysis of a three-tier PKCepsilon-Akt-eNOS signaling module in cardiac protection.	AKT1 NOS3	3.53e-05	3	120	2	15528226
Pubmed	Follistatin-like 1, a secreted muscle protein, promotes endothelial cell function and revascularization in ischemic tissue through a nitric-oxide synthase-dependent mechanism.	AKT1 NOS3	3.53e-05	3	120	2	18718903
Pubmed	MicroRNA-615-5p Regulates Angiogenesis and Tissue Repair by Targeting AKT/eNOS (Protein Kinase B/Endothelial Nitric Oxide Synthase) Signaling in Endothelial Cells.	AKT1 NOS3	3.53e-05	3	120	2	31092013
Pubmed	Erythropoietin-mobilized endothelial progenitors enhance reendothelialization via Akt-endothelial nitric oxide synthase activation and prevent neointimal hyperplasia.	AKT1 NOS3	3.53e-05	3	120	2	16645141
Pubmed	Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis.	TSC2 AKT1	3.53e-05	3	120	2	24161930
Pubmed	Association of PI3K/AKT/mTOR pathway autophagy-related gene polymorphisms with pulmonary tuberculosis susceptibility in a Chinese population.	TSC2 AKT1	3.53e-05	3	120	2	37493735
Pubmed	Association of eNOS and HSP70 gene polymorphisms with glaucoma in Pakistani cohorts.	HSPA4 NOS3	3.53e-05	3	120	2	20069064
Pubmed	Phosphorylation of endothelial nitric-oxide synthase regulates superoxide generation from the enzyme.	AKT1 NOS3	3.53e-05	3	120	2	18622039
Pubmed	Overexpression of the β2AR gene improves function and re-endothelialization capacity of EPCs after arterial injury in nude mice.	AKT1 NOS3	3.53e-05	3	120	2	27194135
Pubmed	Flow shear stress stimulates Gab1 tyrosine phosphorylation to mediate protein kinase B and endothelial nitric-oxide synthase activation in endothelial cells.	AKT1 NOS3	3.53e-05	3	120	2	15665327
Pubmed	Evidence for the role of PI(3) -kinase-AKT-eNOS signalling pathway in secondary inflammatory process after spinal cord compression injury in mice.	AKT1 NOS3	3.53e-05	3	120	2	21496122
Pubmed	Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells.	PLXNA4 PLXNA2	3.53e-05	3	120	2	18625214
Pubmed	Endothelial nitric oxide synthase phosphorylation in treadmill-running mice: role of vascular signalling kinases.	AKT1 NOS3	3.53e-05	3	120	2	19505983
Pubmed	Endothelin-1 inhibits thick ascending limb transport via Akt-stimulated nitric oxide production.	AKT1 NOS3	3.53e-05	3	120	2	19033447
Pubmed	Repression of TSC1/TSC2 mediated by MeCP2 regulates human embryo lung fibroblast cell differentiation and proliferation.	TSC2 MECP2	3.53e-05	3	120	2	28041914
Pubmed	Molecular mechanisms of ghrelin-mediated endothelial nitric oxide synthase activation.	AKT1 NOS3	3.53e-05	3	120	2	18450953
Interaction	METTL18 interactions	RARS1 TAGAP SRP68 PRPF4 DDX39A HSPA4	1.67e-06	62	118	6	int:METTL18
Interaction	HECTD1 interactions	NOLC1 DNAJC13 DCTN2 SCAF8 POLE CKAP5 SRP68 RRP8 KIF20B NCAPG DDX46 PRPF4 CDK13 TPX2 DDX54 DLD MPHOSPH10 DDX39A HSPA4	4.30e-06	984	118	19	int:HECTD1
Interaction	DNAH8 interactions	KMT2A DNAH8 HSPA4 VDAC2	5.03e-06	20	118	4	int:DNAH8
Interaction	YWHAZ interactions	TANC2 NOLC1 RASGRF2 TEX2 PPFIA1 SIPA1L3 CKAP5 TSC2 PPFIA3 PCGF5 THAP9 USP31 PTPN13 MCTP1 KMT2A DLD AKT1 PLCH1 PDE7B HSPA4 VDAC2 GAREM1	7.30e-06	1319	118	22	int:YWHAZ
Interaction	YWHAE interactions	TANC2 NOLC1 PPFIA1 SIPA1L3 CKAP5 TSC2 TTLL7 USP31 ZNF106 PTPN13 CDK13 DDX54 KMT2A DLD AKT1 H1-1 PLCH1 DDX39A PDE7B HSPA4 GAREM1	1.17e-05	1256	118	21	int:YWHAE
Interaction	YWHAQ interactions	TANC2 RNASEH2B NOLC1 PPFIA1 SIPA1L3 TSC2 USP31 ZNF106 PTPN13 PRPF4 KMT2A DLD TXNDC9 H1-1 PLCH1 DDX39A PDE7B HSPA4 GAREM1	2.60e-05	1118	118	19	int:YWHAQ
Interaction	GSK3B interactions	DNAJC13 RARS1 TEX2 DCTN2 PPFIA1 SIPA1L3 TSC2 ZDBF2 SGK3 PTPN13 AFAP1 SAP30BP FNIP1 AKT1 CTNND2 HSPA4	4.65e-05	868	118	16	int:GSK3B
Interaction	NR3C1 interactions	TANC2 HYOU1 ACADVL POLE SRP68 RRP8 ZDBF2 XPC PPFIA3 ADCY2 CD4 DDX54 FNIP1 MPHOSPH10 CTNND2 HSPA4 NOMO3	5.22e-05	974	118	17	int:NR3C1
Interaction	DNAJC3 interactions	HYOU1 CNTRL GSR NOMO2 KMT2A ROS1 DNAJC1 HSPA4	5.61e-05	226	118	8	int:DNAJC3
GeneFamily	Plexins	PLXNA4 PLXNA2	7.70e-04	9	85	2	683
GeneFamily	Sterile alpha motif domain containing	PPFIA4 PPFIA1 PPFIA3 ANKS4B	7.86e-04	88	85	4	760
GeneFamily	Serine peptidase inhibitors, Kazal type	SPINK9 SPINK6	9.59e-04	10	85	2	740
GeneFamily	Adenylate cyclases\|Deafness associated genes	ADCY2 ADCY7	9.59e-04	10	85	2	53
GeneFamily	DEAD-box helicases	DDX46 DDX54 DDX39A	1.01e-03	42	85	3	499
GeneFamily	Wiskott-Aldrich Syndrome protein family	WASH6P WASH4P	2.51e-03	16	85	2	14
GeneFamily	Heat shock 70kDa proteins	HYOU1 HSPA4	2.84e-03	17	85	2	583
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	DNAJC13 TRIM2 PPFIA1 KIF20B TTLL7 PTPN13 DDX46 PRPF4 DNAJC1 MPHOSPH10 QSER1 CTNND2 GAREM1	9.24e-06	656	119	13	M18979
Coexpression	PUJANA_XPRSS_INT_NETWORK	RNASEH2B POLE CNTRL KIF20B DDX46 PRPF4 DDX39A	1.20e-05	168	119	7	M18811
Coexpression	GSE7568_IL4_VS_IL4_AND_TGFB_TREATED_MACROPHAGE_24H_DN	RARS1 SRP68 GSR NOMO1 AKT1 DDX39A HSPA4	2.49e-05	188	119	7	M367
Coexpression	RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP	DNAJC13 RARS1 CTDSPL2 CKAP5 KIF20B USP31 TPX2 TXNDC9 ELF4 MPHOSPH10 QSER1 DDX39A HSPA4	2.49e-05	721	119	13	M10237
Coexpression	PUJANA_BRCA2_PCC_NETWORK	RNASEH2B POLE CNTRL CKAP5 PEX1 KIF20B DDX46 PRPF4 TPX2 DDX39A	2.55e-05	426	119	10	M9516
Coexpression	PUJANA_CHEK2_PCC_NETWORK	RNASEH2B NOLC1 POLE CNTRL KIF20B GSR DDX46 PRPF4 TPX2 DLD MPHOSPH10 DDX39A HSPA4	4.34e-05	761	119	13	M11961
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500_k-means-cluster#5	CKAP5 ZDBF2 KIF20B DDX46 TPX2 DNAJC1 MPHOSPH10 CTNND2 HSPA4	5.26e-06	232	116	9	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500_K5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3	CKAP5 ZDBF2 KIF20B DDX46 TPX2 DNAJC1 MPHOSPH10 HSPA4	1.07e-05	192	116	8	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3
CoexpressionAtlas	alpha beta T cells, T.DPbl.Th, 4+ 8+ TCR-/lo FSChi, Thymus, avg-3	RNASEH2B POLE CKAP5 KIF20B NCAPG CD4 LRRC42 TPX2 H1-1 QSER1 DNAH8	1.18e-05	398	116	11	GSM399397_500
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#5	ZDBF2 KIF20B ZNF106 DDX46 TPX2 MPHOSPH10 CTNND2 HSPA4	1.66e-05	204	116	8	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000_K5
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3	POLE CKAP5 ZDBF2 KIF20B ZNF106 NCAPG DDX46 N4BP2 TPX2 MPHOSPH10 CTNND2 HSPA4	3.50e-05	532	116	12	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	PPFIA1 CKAP5 ZDBF2 RXYLT1 MECP2 KIF20B DDX46 AFAP1 TPX2 FNIP1 DNAJC1 MPHOSPH10 CTNND2 ALDH6A1 HSPA4	4.73e-05	831	116	15	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500_k-means-cluster#5	ZDBF2 KIF20B NCAPG DDX46 QSER1 ALDH6A1 HSPA4	7.38e-05	186	116	7	Facebase_RNAseq_e10.5_Mandibular Arch_500_K5
CoexpressionAtlas	dev gonad_e11.5_M_PrimGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_1000	RNASEH2B DNAJC13 TEX2 POLE PCGF5 KIF20B NCAPG DDX39A	8.74e-05	258	116	8	gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_k2_1000
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000	NOLC1 RARS1 ZDBF2 KIF20B NOMO1 ZNF106 PTPN13 DDX46 TPX2 DDX54 MPHOSPH10 CTNND2 PLCH1 DDX39A HSPA4 CA4	9.72e-05	991	116	16	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000
CoexpressionAtlas	facebase_RNAseq_e10.5_MandArch_2500_K1	NOLC1 CTDSPL2 POLE CNTRL CKAP5 FAM76B ZDBF2 LY96 KIF20B NCAPG DDX46 CD4 HECTD2 TPX2 TSHZ1 MPHOSPH10 QSER1 HSPA4	1.34e-04	1241	116	18	facebase_RNAseq_e10.5_MandArch_2500_K1
CoexpressionAtlas	Fetal Liver, SC.LTSL.FL, IgM- CD24- CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Fetal Liver, avg-3	NCAPG RGS18 MCTP1 TPX2 H1-1	1.50e-04	92	116	5	GSM791126_100
ToppCell	facs-Skin-Telogen-3m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDYN KIF20B NCAPG TPX2 H1-1 PLCH1 DNAH8	7.39e-07	186	120	7	9feef5936985e936b3d88f9d1bb012abb6468570
ToppCell	facs-Skin-Telogen-3m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDYN KIF20B NCAPG TPX2 H1-1 PLCH1 DNAH8	7.39e-07	186	120	7	89f5b06bc56674af304912d481ac697c7c870904
ToppCell	Non-neuronal-Dividing-IPC-IPC-div1-28\|World / Primary Cells by Cluster	CNTRL CKAP5 KIF20B NCAPG TPX2 H1-1 DDX39A	1.16e-06	199	120	7	787688b68ae5d8768c0a24673ae07ab07616764a
ToppCell	Non-neuronal-Dividing-IPC-IPC-div1\|World / Primary Cells by Cluster	CNTRL CKAP5 KIF20B NCAPG TPX2 H1-1 DDX39A	1.16e-06	199	120	7	72823f26ecabcae1b514b7629cfce010c97b929a
ToppCell	LPS-antiTNF-Lymphocytic_NKT-T_cells-Neutrophils\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RNASEH2B TPX2 H1-1 CFAP70 PLCH1 DTHD1	3.72e-06	153	120	6	c4dcdcaa672929c1da870e9fb8ada1bb030ad12f
ToppCell	droplet-Lung-nan-18m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TAGAP TEX2 PPFIA4 CNTRL RGS18 CTNND2	6.81e-06	170	120	6	749144a1a869a6bf9acdd227184319083367dc3f
ToppCell	droplet-Lung-nan-18m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TAGAP TEX2 PPFIA4 CNTRL RGS18 CTNND2	6.81e-06	170	120	6	25d60a62e8f99c31ab64fe6a0c07ccca3df1a7ee
ToppCell	droplet-Spleen-nan-3m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEX2 PPFIA4 OBSCN CD4 C8A CTNND2	8.04e-06	175	120	6	21bc0e59a9509d38751ce6aad2325f341bc70eff
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTLL7 RGS18 MCTP1 PLXNA4 DNAH8 PDE7B	9.15e-06	179	120	6	025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell	facs-Marrow-B-cells-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEX2 PPFIA4 OBSCN CD4 C8A CTNND2	9.44e-06	180	120	6	bf8d13d4db1af55b8c9fe16aaccf8743e000e005
ToppCell	facs-Marrow-B-cells-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEX2 PPFIA4 OBSCN CD4 C8A CTNND2	9.44e-06	180	120	6	839defb40f7cfb2711e9025194de636533f51bcd
ToppCell	facs-Marrow-B-cells-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEX2 PPFIA4 OBSCN CD4 C8A CTNND2	9.44e-06	180	120	6	82965ed1b72a1873c24dd4553d39681596057316
ToppCell	facs-Marrow-B-cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CKAP5 ADTRP KIF20B NCAPG MCTP1 TPX2	1.01e-05	182	120	6	9025178ede571e3808d4657ad4892152f336c9b4
ToppCell	facs-Marrow-B-cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CKAP5 ADTRP KIF20B NCAPG MCTP1 TPX2	1.01e-05	182	120	6	c075756cd4bb484ede1be2bcdb9eac60eab0573a
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN LOXHD1 OTOGL UNC13C ROS1 PLCH1	1.07e-05	184	120	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN LOXHD1 OTOGL UNC13C ROS1 PLCH1	1.07e-05	184	120	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN LOXHD1 OTOGL UNC13C ROS1 PLCH1	1.07e-05	184	120	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CKAP5 LAMA3 KIF20B NCAPG TPX2 DDX39A	1.10e-05	185	120	6	30e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TANC2 LAMA3 PTPN13 ROS1 PLCH1 PLXNA2	1.14e-05	186	120	6	e83718fabb057100835d3357df407f283d23fe16
ToppCell	Control-Endothelial-Endothelial-FOXM1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	POLE CKAP5 KIF20B NCAPG TPX2 H1-1	1.25e-05	189	120	6	1e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell	PCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	LAMA3 NCAPG TPX2 H1-1 CTNND2 PLCH1	1.32e-05	191	120	6	39220f4a345e328f7fa4fd462a0abeea821b3e02
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CKAP5 KIF20B NCAPG TPX2 H1-1 DDX39A	1.32e-05	191	120	6	0ba5b112a82e489f5a21966f78a403a7436ce73b
ToppCell	droplet-Skin-nan-21m-Epithelial-stem_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CKAP5 KIF20B NCAPG TPX2 H1-1 DNAH8	1.36e-05	192	120	6	96f23d6e8604d1cb24910d3118d8171b57c93e14
ToppCell	B_cell_maturation-plasma\|B_cell_maturation / Lineage and Cell class	HYOU1 ACADVL LY96 ADTRP IGHG4 DNAJC1	1.40e-05	193	120	6	5415f7e54bc40aec3dbe27fd97f6e9be6db08a48
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	POLE CKAP5 KIF20B NCAPG TPX2 H1-1	1.44e-05	194	120	6	3a49c7c86036e09a8cd0114988380d04ad1a26fb
ToppCell	droplet-Thymus-nan-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNASEH2B CKAP5 KIF20B NCAPG TPX2 H1-1	1.49e-05	195	120	6	043e2f19d95e94cd5219e2c415f322ed340aa80f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CNTRL LY96 ADCY7 RGS18 CD4 MCTP1	1.53e-05	196	120	6	cbc727b55b6433a701b1a331028a49960fcee6ee
ToppCell	droplet-Thymus-nan-18m-Lymphocytic-DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNASEH2B CKAP5 KIF20B NCAPG TPX2 H1-1	1.53e-05	196	120	6	5ddd314d3def3776dc7da83778d41c6436ca51ac
ToppCell	Severe\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	HYOU1 ACADVL NOMO1 IGHG4 TPX2 DNAJC1	1.58e-05	197	120	6	df3f58b58f82c42c65b0a09c054b669b34502037
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRIM2 CKAP5 KIF20B NCAPG TPX2 CTNND2	1.58e-05	197	120	6	6de02b02fcdfcab1c1b0f4a4c75677410bc55688
ToppCell	T_cells-Treg_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	ZDBF2 LY96 ADTRP CD4 DNAH8 PDE7B	1.58e-05	197	120	6	ec9398ae3577f61d6b1e6aba50ef4261aaaa7610
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating-cycling_dorsal_progenitors\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	CNTRL CKAP5 KIF20B NCAPG TPX2 DDX39A	1.62e-05	198	120	6	5f0964c3aa7e1dc52cbb46e754078920b65bcb88
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	CNTRL CKAP5 KIF20B NCAPG TPX2 DDX39A	1.62e-05	198	120	6	629d674a9c9108c1acb3f7af57bbdbf34bb0528e
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CNTRL CKAP5 KIF20B NCAPG TPX2 DDX39A	1.62e-05	198	120	6	c3dd887c95587f930b7afd32385627a9fa029ca4
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_plasmacytoid\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TAGAP KIF20B RGS18 CD4 IGHG4 ELF4	1.62e-05	198	120	6	c64238379798ae6b292cc1914d60548c88e652de
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	TANC2 CNTRL KIF20B ZNF106 PTPN13 DNAJC1	1.62e-05	198	120	6	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-B_cells-Cycling_plasma_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CNTRL CKAP5 KIF20B NCAPG TPX2 DDX39A	1.67e-05	199	120	6	c9d15c84b9f8c87b4ea0008be7d5efc5f45efd1a
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating-cycling_dorsal_progenitors\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	CNTRL CKAP5 KIF20B NCAPG TPX2 DDX39A	1.67e-05	199	120	6	ca17e8c0f5bc2c41ce28351a7418d934404e563b
ToppCell	10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-pre_pro_B_progenitor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	RNASEH2B KIF20B NCAPG TPX2 H1-1 DDX39A	1.67e-05	199	120	6	99778178e3ec121802db938db8c5475d19b43fec
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-FOXM1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	POLE CNTRL CKAP5 KIF20B NCAPG TPX2	1.67e-05	199	120	6	98575fcce726589e93fbb4df1aab03e57cb56076
ToppCell	LPS_IL1RA-Endothelial-Endothelial-FOXM1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	POLE CNTRL CKAP5 KIF20B NCAPG TPX2	1.67e-05	199	120	6	be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	POLE CNTRL CKAP5 KIF20B NCAPG TPX2	1.72e-05	200	120	6	4cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells-Neuroepithelial_cell\|2m / Sample Type, Dataset, Time_group, and Cell type.	RNASEH2B CNTRL CKAP5 KIF20B NCAPG TPX2	1.72e-05	200	120	6	0d9b8d51a7630e70e60c76c763ff82df4c559152
ToppCell	Control_saline-Endothelial-Endothelial-FOXM1\|Control_saline / Treatment groups by lineage, cell group, cell type	POLE CNTRL CKAP5 KIF20B NCAPG TPX2	1.72e-05	200	120	6	9bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	TANC2 DCTN2 BBS10 DDX46 LRRC42 TXNDC9	1.72e-05	200	120	6	1fa8422fd820d21e285a7e7c4c6fbd8b7277d2af
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells\|2m / Sample Type, Dataset, Time_group, and Cell type.	RNASEH2B CNTRL CKAP5 KIF20B NCAPG TPX2	1.72e-05	200	120	6	0675f580ccef705875854247bbfd4ee2bcf126a1
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCGF5 KIF20B GSR NCAPG TPX2	4.74e-05	146	120	5	45d7cb73776e60d22f335a651845e21e16948fcc
ToppCell	facs-Heart-RV-18m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TAGAP PPFIA4 LIPN RGS18 MCTP1	5.93e-05	153	120	5	af0ae08ff35f8210268457e5e15bcbe5d1f46d67
ToppCell	facs-Heart-RV-18m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TAGAP PPFIA4 LIPN RGS18 MCTP1	5.93e-05	153	120	5	984a2d847f4376183fdbab7ebc77c1bf7d448f44
ToppCell	LPS_only-Myeloid-Monocytes,_Macrophages-T-cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PPFIA4 NCAPG RGS18 H1-1 ELF4	6.90e-05	158	120	5	91d8c93af328c3bbebe1d8f019b94849ebc548c0
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	POLE KIF20B NCAPG TPX2 H1-1	7.54e-05	161	120	5	0dd1401b4c990d49fccb702a9f9867590a58e203
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	POLE KIF20B NCAPG TPX2 H1-1	7.54e-05	161	120	5	b6a31c033edc74f23a20aab1f18e80cc83ffee4c
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	POLE KIF20B NCAPG TPX2 H1-1	7.54e-05	161	120	5	efb811dda4d73107983a5f68302bdcf4f408d5b4
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	POLE KIF20B NCAPG TPX2 H1-1	7.54e-05	161	120	5	28d5dbd20c9f8e0069f172d552997a044790e1a7
ToppCell	facs-Large_Intestine-Proximal-24m-Epithelial-Enterocyte_(Proximal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIA3 ADTRP LRRC42 SDCBP2 CA4	8.47e-05	165	120	5	ce79d217df88035457cd58f679e72dd98722ae22
ToppCell	droplet-Lung-LUNG-1m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEX2 PPFIA4 RGS18 CD4 CTNND2	8.71e-05	166	120	5	6e6075d0c913e2516083f6dcab21d5878bcef7a4
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CKAP5 KIF20B CD4 TPX2 DNAH8	8.71e-05	166	120	5	a41a20cef053c67da2d435e3e132ce28f1661c03
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-Enterocyte_(Proximal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIA3 ANKS4B ADTRP SDCBP2 CA4	8.71e-05	166	120	5	22b31acbbef1936ce19b393cf880c63ea2fa0f1b
ToppCell	droplet-Lung-1m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TEX2 PPFIA4 RGS18 CD4 CTNND2	8.71e-05	166	120	5	1ca888ae8168707493f19ee52a89d7c70e6cb51d
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEX2 PPFIA4 RGS18 CD4 CTNND2	8.71e-05	166	120	5	4fbe44e0aea197893614cd55f83119aa0f73ee53
ToppCell	droplet-Lung-1m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TEX2 PPFIA4 RGS18 CD4 CTNND2	8.71e-05	166	120	5	4cba4ca1aa2321b9ef7cd230932b890d2434a252
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF20B NCAPG CD4 TPX2 DNAH8	8.96e-05	167	120	5	754e6412d3b9cc0b126e59593df2f5956b4712ef
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PPFIA4 KIF20B NCAPG RGS18 TPX2	9.22e-05	168	120	5	b7cd33f5da4f37b9384fc3bd3ca01fbc790accfc
ToppCell	droplet-Liver-LIVER-NPC-1m-Myeloid-plasmacytoid_dendritic_cells\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIA4 OBSCN RGS18 CD4 CTNND2	9.22e-05	168	120	5	e8878ec68b21c8d5694d7209b816d2f869673164
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	POLE KIF20B PTPN13 RGS18 TPX2	9.22e-05	168	120	5	a7eb28e15b591997f1aee09501cb20ae18beca08
ToppCell	droplet-Liver-LIVER-NPC-1m-Myeloid-plasmacytoid_dendritic_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIA4 OBSCN RGS18 CD4 CTNND2	9.22e-05	168	120	5	a007758c219d3d5db2b5529f29af63be0d408304
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	POLE LAMA3 DMC1 NCAPG TPX2	9.48e-05	169	120	5	0bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	POLE LAMA3 TTLL7 DMC1 NCAPG	9.48e-05	169	120	5	121768fc51fc3441ec725346a1bbe29e21d05971
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	OTOGL ROS1 DNAJC1 PLCH1 CA4	9.74e-05	170	120	5	5de2f7d16a05af74ebfb1ca42d0f9c3c3524692d
ToppCell	facs-Marrow-T-cells-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEX2 PPFIA4 CD4 C8A CTNND2	1.00e-04	171	120	5	6a0fafb8fd9fc7671618eeb2bf528ce8ce86b794
ToppCell	facs-Marrow-T-cells-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEX2 PPFIA4 CD4 C8A CTNND2	1.00e-04	171	120	5	e02b5831768dbb1b68998b672e55c9680ab0cc86
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RNASEH2B KIF20B NCAPG TPX2 H1-1	1.00e-04	171	120	5	846a9acfff0bf0a9baf65dc07b7d7a9217ed6598
ToppCell	3'-Adult-Distal_Rectal-Epithelial-Tuft-related-BEST4+_epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA3 ADCY7 ELF4 SDCBP2 CA4	1.00e-04	171	120	5	317b70d72a4ca5336cfb6a49dc57f8e2a8a1c736
ToppCell	droplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TEX2 PPFIA4 CNTRL RGS18 CTNND2	1.03e-04	172	120	5	422d311bba2dd5d8bece4e96ee8c86e78086b62d
ToppCell	droplet-Liver-LIVER-30m-Myeloid-plasmacytoid_dendritic_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TAGAP PPFIA4 OBSCN RGS18 CTNND2	1.03e-04	172	120	5	24ecfda5e43e28f190089770cd2eae5bf2ed292b
ToppCell	droplet-Liver-LIVER-30m-Myeloid-plasmacytoid_dendritic_cells\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TAGAP PPFIA4 OBSCN RGS18 CTNND2	1.03e-04	172	120	5	db5a31cafce4346fe459d7f35210823fd7004439
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(15)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CKAP5 KIF20B NCAPG TPX2 DDX39A	1.03e-04	172	120	5	7f3d0ef18f5df1ed80498d435b0378ca398c0b88
ToppCell	droplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TEX2 PPFIA4 CNTRL RGS18 CTNND2	1.03e-04	172	120	5	1abb6fbb28c8aff384540493d0f70eeacaa751f4
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	OTOGL UNC13C ROS1 PLCH1 PDE7B	1.06e-04	173	120	5	8335b77f730ed43fc348a005566e73a103c6774b
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Proliferating_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNASEH2B ZDBF2 RGS18 TPX2 CTNND2	1.06e-04	173	120	5	6c9ecf77d2fb0f89100fdd7e4e88f85598278bc7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	POLE KIF20B DMC1 NCAPG TPX2	1.09e-04	174	120	5	84da9faff088d05233183b425385beb054c92d1b
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PPFIA3 ADTRP KIF20B NCAPG TPX2	1.09e-04	174	120	5	7b2f35add804981c7d588a996bdbca6ec11a1ca5
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CKAP5 KIF20B NCAPG TPX2 NOS3	1.12e-04	175	120	5	d43ae33a6256606ce848247cad32d74f21b38988
ToppCell	Dividing_Macrophages-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	NCAPG IGHG4 TPX2 H1-1 C8A	1.12e-04	175	120	5	0a8bf455babb3271aa00642199fb58b0b02dc3ac
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CKAP5 KIF20B NCAPG CD4 TPX2	1.12e-04	175	120	5	9de288c338cee67be0e9b836c87799bbc1db1c38
ToppCell	facs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEX2 PPFIA4 OBSCN CD4 CTNND2	1.15e-04	176	120	5	74f851a398c7562dd713bc0d8d488c0037243112
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CKAP5 KIF20B TTLL7 NCAPG TPX2	1.15e-04	176	120	5	75412d58438d71c49a6096bb2ef12b7f349653d8
ToppCell	facs-Marrow-T_cells-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEX2 PPFIA4 OBSCN CD4 CTNND2	1.15e-04	176	120	5	31b5459a978d5cdde0af03a77401e0464d8c95ba
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	OTOGL UNC13C ROS1 PLCH1 PDE7B	1.15e-04	176	120	5	40993c41c1017b53039a337174fc56632b278609
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	POLE DMC1 NCAPG HECTD2 TPX2	1.18e-04	177	120	5	3e149bff1f1b393a7abe98984e37981c8296f95d
ToppCell	facs-Skin-Anagen-24m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF20B NCAPG TPX2 CFAP70 DNAH8	1.18e-04	177	120	5	8a0f0fbb06cdacb99a3fdba0da3e0494b891db4f
ToppCell	facs-Skin-Anagen-24m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF20B NCAPG TPX2 CFAP70 DNAH8	1.18e-04	177	120	5	e9d7682517fb30fd2ad535d59779d718a7024c13
ToppCell	droplet-Spleen-SPLEEN-1m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TEX2 PPFIA4 LRRN3 RGS18 CTNND2	1.21e-04	178	120	5	742ee0cb8cb585a5e34bd5b20aebe9bb99756e0c
ToppCell	droplet-Lung-30m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SRP68 KIF20B NCAPG DLD DDX39A	1.24e-04	179	120	5	af03705a783e77f75c44fdfa793cfdccbf9dd91c
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NIPAL4 OBSCN ADCY2 CTNND2 PDE7B	1.24e-04	179	120	5	a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CKAP5 KIF20B NCAPG TPX2 H1-1	1.27e-04	180	120	5	5e1680088065be14447d5d5465f91f7edd071a1e
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	TANC2 PTPN13 ROS1 PLCH1 GAREM1	1.27e-04	180	120	5	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(15)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CKAP5 KIF20B NCAPG TPX2 DDX39A	1.27e-04	180	120	5	ed4966765a6b25456f68185cf0648c4a3a21d7fe
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-Proliferating_T_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KIF20B NCAPG CD4 TPX2 H1-1	1.31e-04	181	120	5	cf13bf7a531a2d40f8d778629cf2431b684f65f3
ToppCell	facs-Marrow-T-cells-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TAGAP TEX2 PPFIA4 CD4 C8A	1.31e-04	181	120	5	7286700396676fdc41d9723979b8b408177aceb9
Disease	Epilepsy	TANC2 TSC2 MECP2 AKT1 VDAC2	6.97e-05	109	115	5	C0014544
Disease	Manic	ADCY2 ITIH1 DNAH8 HSPA4	2.50e-04	78	115	4	C0338831
Disease	Hypoxemia	ACADVL PDYN NOS3	2.89e-04	33	115	3	C0700292
Disease	Hypoxia	ACADVL PDYN NOS3	2.89e-04	33	115	3	C0242184
Disease	Anoxemia	ACADVL PDYN NOS3	2.89e-04	33	115	3	C0003129
Disease	Anoxia	ACADVL PDYN NOS3	2.89e-04	33	115	3	C0003130
Disease	retinal degeneration (implicated_via_orthology)	DCTN2 NOS3 VDAC2	2.89e-04	33	115	3	DOID:8466 (implicated_via_orthology)
Disease	Epilepsy, Cryptogenic	TSC2 MECP2 AKT1 VDAC2	3.03e-04	82	115	4	C0086237
Disease	Awakening Epilepsy	TSC2 MECP2 AKT1 VDAC2	3.03e-04	82	115	4	C0751111
Disease	Aura	TSC2 MECP2 AKT1 VDAC2	3.03e-04	82	115	4	C0236018
Disease	Colorectal Carcinoma	RASGRF2 POLE OBSCN LY96 NCAPG TPX2 AKT1 CTNND2 SDCBP2 DNAH8	4.32e-04	702	115	10	C0009402
Disease	lung cancer (implicated_via_orthology)	POLE XPC	5.32e-04	9	115	2	DOID:1324 (implicated_via_orthology)
Disease	Congenital Nonbullous Ichthyosiform Erythroderma	NIPAL4 LIPN	8.09e-04	11	115	2	C0079154
Disease	Congenital ichthyosis of skin	NIPAL4 LIPN	8.09e-04	11	115	2	cv:C0020758
Disease	Amino Acid Metabolism, Inherited Disorders	XPC ALDH6A1	1.14e-03	13	115	2	C0750905
Disease	Respiratory Depression	PDYN MECP2	1.14e-03	13	115	2	C0235063
Disease	Respiratory Insufficiency	PDYN MECP2	1.14e-03	13	115	2	C0035229
Disease	Respiratory Failure	PDYN MECP2	1.14e-03	13	115	2	C1145670
Disease	Amino Acid Metabolism, Inborn Errors	XPC ALDH6A1	1.14e-03	13	115	2	C0002514
Disease	Small cell carcinoma of lung	ZDBF2 KMT2A AKT1	1.24e-03	54	115	3	C0149925
Disease	Squamous cell carcinoma	TSC2 XPC AKT1 VDAC2	1.43e-03	124	115	4	C0007137
Disease	Seizures	TANC2 RARS1 PDYN TSC2 MECP2	1.67e-03	218	115	5	C0036572
Disease	Chromosome Aberrations	XPC KMT2A	1.74e-03	16	115	2	C0008625
Disease	Autosome Abnormalities	XPC KMT2A	1.74e-03	16	115	2	C0004403
Disease	Huntington's disease (biomarker_via_orthology)	GSR NOS3	1.74e-03	16	115	2	DOID:12858 (biomarker_via_orthology)
Disease	transient cerebral ischemia (implicated_via_orthology)	GSR KMT2A NOS3	2.02e-03	64	115	3	DOID:224 (implicated_via_orthology)
Disease	susceptibility to vaginal yeast infection measurement	ANKRD31 TEX2 HECTD2	2.11e-03	65	115	3	EFO_0008412
Disease	myocardial infarction (implicated_via_orthology)	AKT1 NOS3 VDAC2	2.21e-03	66	115	3	DOID:5844 (implicated_via_orthology)
Disease	Bipolar Disorder	PDYN ADCY2 ITIH1 AKT1 DNAH8 HSPA4 NOS3	2.70e-03	477	115	7	C0005586
Disease	breast cancer (is_implicated_in)	CYP17A1 PTPN13 AKT1 NOS3	2.87e-03	150	115	4	DOID:1612 (is_implicated_in)
Disease	muscular dystrophy (implicated_via_orthology)	TRIM2 SGCD	3.01e-03	21	115	2	DOID:9884 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LGKGTFGKVILVKEK	AKT1	156	P31749
KSLNLSLSKDGGKKF	CNTRL	101	Q7Z7A1
TGLLSSIKKFIKGST	CTDSPL2	46	Q05D32
LLSKVKKDKSDSFGV	C8A	236	P07357
SVKVSVFFGGLSIKK	DDX39A	141	O00148
EAKGTVSKVTGKKIT	AFAP1	311	Q8N556
VSKVTGKKITKIISL	AFAP1	316	Q8N556
KFSQVKEVKKTLSGL	GSR	291	P00390
VATKTKATGASKKLK	H1-1	126	Q02539
VLKRTKGGKDIKFLT	ADTRP	66	Q96IZ2
KPKFSGVEKIKTIGS	ADCY7	921	P51828
KFKDKRVGTKGLDFS	DCTN2	56	Q13561
DIKKLKSVGICTIKG	DMC1	36	Q14565
LKKTGDGAKTFIIFL	BBS10	76	Q8TAM1
KKKTGSKSVDVSKLG	DNAJC1	191	Q96KC8
KATKKAVIVGKESKS	CDK13	556	Q14004
GIEKLVGISKSKGDK	CTNND2	986	Q9UQB3
GVDFKIKTVELRGKK	RAB12	76	Q6IQ22
KGVKFLLFSSLVTKE	NOMO3	231	P69849
KKAAVVVSKSGSLKK	NOLC1	571	Q14978
DSKAKSGGTAISKIK	QSER1	1621	Q2KHR3
LVFGSALLKKGKFGK	ARHGAP36	381	Q6ZRI8
KTTLGKELASKSGLK	AK6	16	Q9Y3D8
KAITSKKVLCSTGGK	ANKRD31	911	Q8N7Z5
KLFIGGKFVESKSDK	ALDH6A1	41	Q02252
KGVKFLLFSSLVTKE	NOMO2	231	Q5JPE7
VTVGTIKKFLSLKLK	PCGF5	171	Q86SE9
GFFLEDKKTKIASTK	LIPN	231	Q5VXI9
VKFKIGGKEVFRSKI	MCTP1	286	Q6DN14
FALGTDGKKLRIKSK	LAMA3	3046	Q16787
KEKISKFFGKELSTT	HSPA4	351	P34932
LAAQTIKKSFSGKKG	ITIH1	216	P19827
KGIFKLVDSKAVSKL	ELF4	236	Q99607
VKKTDGTLKFVHFGK	SPINK9	71	Q5DT21
KSIKSSIGRLFGKKE	PPFIA3	761	O75145
KGIKSSIGRLFGKKE	PPFIA4	751	O75335
LKKKLKVTFVGEAGL	HECTD2	441	Q5U5R9
KLQLTSKSKSAFEKG	LOXHD1	76	Q8IVV2
TKELGKFTGLKTALI	DDX54	186	Q8TDD1
GKKTEFITFDLTTKK	FBXW12	306	Q6X9E4
ISLTAGAIKKKKPAF	PLGRKT	66	Q9HBL7
VFVGTKSGKLKKIRA	PLXNA2	446	O75051
AFVGTKSGKLKKIRV	PLXNA4	446	Q9HCM2
GKGTIKKKFLEELLT	MYLPF	111	Q96A32
AKLSGSFLKELEKSK	PDYN	96	P01213
STTYSGEIGTKKKVK	PDE7B	56	Q9NP56
GEIGTKKKVKRLLSF	PDE7B	61	Q9NP56
KNFIKSGTTFKVKVG	DNAH8	3531	Q96JB1
TIFKKIGKLNSISKL	GAREM1	176	Q9H706
LATKKKEGTLQKFGD	KIF20B	1721	Q96Q89
KGVKFLLFSSLVTKE	NOMO1	231	Q15155
KGIKSSIGRLFGKKE	PPFIA1	801	Q13136
SEKLKQLTKTGKASF	MPHOSPH10	616	O00566
AALSKGKKFDKSGSI	FAM76B	321	Q5HYJ3
SGTGLKDIKTVKHKL	LRRC42	266	Q9Y546
SLSKGIKDTFKIKFK	ANKS4B	196	Q8N8V4
VSSFLSKKFQGKIAK	POLE	116	Q07864
KGTGITRKKTFKEVA	NOS3	486	P29474
KVKKGSSITFSVKVE	OBSCN	5381	Q5VST9
LLSKPKFSGVEKIKT	ADCY2	926	Q08462
IFKKIGSKENTKEGL	CKAP5	1836	Q14008
LTTVKLKGVGDSFKK	HYOU1	516	Q9Y4L1
IVTTKAKVDKKLGRF	CA4	56	P22748
LVTIPKGKAGKTEKT	CFAP70	316	Q5T0N1
RKKKIAIGVIFSLSK	FNIP1	326	Q8TF40
LAKEVLIKKGKDFSG	CYP17A1	81	P05093
KKVVLGKKGDTVELT	CD4	26	P01730
KFKLNTKVTGATKKS	DLD	271	P09622
LKKESFTVTKKGLAL	DTHD1	301	Q6ZMT9
TFRKGSGKKSETLKF	DNAJC13	71	O75165
TISFSFKGIKFSKGK	LY96	116	Q9Y6Y9
FCKAIVKSGGKISLK	SPINK6	61	Q6UWN8
GDTTAVKTKILIKKG	KMT2A	951	Q03164
TEKKPKKGLVFEISS	KMT2A	3661	Q03164
KGLPSSIEKTISKAK	IGHG4	206	P01861
GSFTLGKKQASKSKL	H1-9P	171	P60008
KAEGKIIKKSSGFSG	DDX46	761	Q7L014
KLSSGSYKIGSKVIK	SCAF8	531	Q9UPN6
FKTSLQILDKSTKGK	RXYLT1	81	Q9Y2B1
KVIGKGSFGKVLLAK	SGK3	166	Q96BR1
KGSGKSTLAKAICKE	PEX1	601	O43933
KGTGKDKFTITLQKA	OTOGL	511	Q3ZCN5
LIKSEKGSLGFTVTK	PTPN13	1791	Q12923
STLGEKSGKGLKTCK	MECP2	326	P51608
FGVVLGEDKKKFKTR	RARS1	441	P54136
FTTKTEKGKPSREIK	TAGAP	491	Q8N103
AGKEKSTSLKVKATV	LRRN3	686	Q9H3W5
ILSVVGTDALKKTKK	PRPF4	136	O43172
KEGTKRGFLSKKTAE	RASGRF2	21	O14827
TGKFNLISLTSKKKE	SIPA1L3	841	O60292
IFKGLSKKVGVSSSI	TANC2	821	Q9HCD6
KLEQKTKSGLTGYIK	SRP68	606	Q9UHB9
VIKKGKIVSLVKGSS	SDCBP2	206	Q9H190
FKGILLFGTKAQKEK	ACADVL	186	P49748
TFGIEPFKTKKIKTL	NCAPG	651	Q9BPX3
SKEKTFFKLIHGSGK	RGS18	16	Q9NS28
LKKSYKLKGTGIGIS	UNC13C	391	Q8NB66
SIDTFFGVKNKKKIG	RNASEH2B	296	Q5TBB1
ASKIGSLLFVKKKNG	THAP9	746	Q9H5L6
KKFEVKTVSGKLLFS	SGCD	136	Q92629
RKAGIKSTIAIEKFK	UBE4B	1191	O95155
KIKGSKKAIKVFSSA	WASH4P	91	A8MWX3
TKKKVKIGTVEFPAS	ZDBF2	1981	Q9HCK1
KGFGFGLVKLDVKTK	VDAC2	31	P45880
GSGEIKVAVKTLKKG	ROS1	1971	P08922
AVTKLGFKIVSKDLT	RRP8	406	O43159
KERTKIEFVTGTKKG	SAP30BP	216	Q9UHR5
KSFVTTGIRDKKGVT	PLCH1	1516	Q4KWH8
SSFLIGSSVILKKKG	NIPAL4	66	Q0D2K0
LKLLVKKCSKGTGFS	ZZEF1	2381	O43149
KTALLSKKAGGSSVK	USP31	1246	Q70CQ4
VKGIKGFEAEFIKSK	TRAV8-1	76	A0A0A6YYK1
KTSKGTKQEETFAKG	XPC	361	Q01831
SSDGKFKTKIGSGKL	TRIM2	561	Q9C040
LASKLKSEIKKSSGV	TEX2	706	Q8IWB9
EKGCLLKTKGGITKE	TIGD7	446	Q6NT04
KFGTNFTKLEKKTIR	TXNDC9	201	O14530
IKGSKKAIKVFSSAK	WASH6P	61	Q9NQA3
KAGKLIKGGKVTTST	ZNF106	1386	Q9H2Y7
FLKVTTSASKKGKQL	TSHZ1	441	Q6ZSZ6
KKKGTITANVAGTKF	TTLL7	36	Q6ZT98
SKDSGLKEKFKILLG	TSC2	6	P49815
KKEKKSVAEGLSGSL	TPX2	641	Q9ULW0
TVTKKAFGKQKSKST	N4BP2	761	Q86UW6