Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionkainate selective glutamate receptor activity

GRIK1 GRIK2 GRIK3

7.17e-076673GO:0015277
GeneOntologyMolecularFunctionneurotransmitter receptor activity

GABRP DRD1 GRIK1 GRIK2 GRIK3

2.15e-05100675GO:0030594
GeneOntologyMolecularFunctionglutamate-gated receptor activity

GRIK1 GRIK2 GRIK3

2.37e-0517673GO:0004970
GeneOntologyMolecularFunctionsodium channel activity

NALCN GRIK1 GRIK2 GRIK3

2.78e-0552674GO:0005272
GeneOntologyMolecularFunctionligand-gated sodium channel activity

GRIK1 GRIK2 GRIK3

2.84e-0518673GO:0015280
GeneOntologyMolecularFunctiontransmitter-gated channel activity

GABRP GRIK1 GRIK2 GRIK3

6.72e-0565674GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

GABRP GRIK1 GRIK2 GRIK3

6.72e-0565674GO:0022824
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

GRIK1 GRIK2 GRIK3

6.95e-0524673GO:0099507
GeneOntologyMolecularFunctionglutamate receptor activity

GRIK1 GRIK2 GRIK3

9.97e-0527673GO:0008066
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

DRD1 GRIK1 GRIK2 GRIK3

1.18e-0475674GO:0098960
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

GABRP GRIK1 GRIK2 GRIK3

1.30e-0477674GO:0005230
GeneOntologyMolecularFunctionextracellularly glutamate-gated ion channel activity

GRIK1 GRIK2

2.30e-047672GO:0005234
GeneOntologyMolecularFunctioncyclic nucleotide binding

PRKAR2A CNP PDE11A

3.03e-0439673GO:0030551
GeneOntologyMolecularFunctionphosphoric diester hydrolase activity

PLCB1 PLCL1 CNP PDE11A

3.17e-0497674GO:0008081
GeneOntologyMolecularFunctioncysteine-type endopeptidase inhibitor activity

PTTG3P PTTG1 PTTG2

4.05e-0443673GO:0004869
GeneOntologyMolecularFunctionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines

ALLC PADI4

5.98e-0411672GO:0016813
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNAH3 DNAH2 KIF14 MYH15

6.67e-04118674GO:0003774
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

GRIK1 GRIK2 GRIK3

9.28e-0457673GO:1904315
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

GRIK1 GRIK2 GRIK3

1.08e-0360673GO:0099529
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH3 DNAH2

1.64e-0318672GO:0008569
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH3 DNAH2 KIF14

1.68e-0370673GO:0003777
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

NALCN GRIK1 GRIK2 GRIK3

2.62e-03171674GO:0015081
GeneOntologyMolecularFunctionendopeptidase inhibitor activity

USP14 PTTG3P PTTG1 PTTG2

3.15e-03180674GO:0004866
GeneOntologyMolecularFunctionphosphatidylinositol phospholipase C activity

PLCB1 PLCL1

3.42e-0326672GO:0004435
GeneOntologyMolecularFunctionATP hydrolysis activity

DNAH3 BRIP1 ATRX DNAH2 KIF14 SRPRA

3.59e-03441676GO:0016887
GeneOntologyMolecularFunctionpeptidase inhibitor activity

USP14 PTTG3P PTTG1 PTTG2

3.61e-03187674GO:0030414
GeneOntologyMolecularFunctioncyclic-nucleotide phosphodiesterase activity

CNP PDE11A

3.69e-0327672GO:0004112
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH3 DNAH2

3.96e-0328672GO:0051959
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

GABRP GRIK1 GRIK2 GRIK3

4.03e-03193674GO:0015276
GeneOntologyMolecularFunctionphospholipase C activity

PLCB1 PLCL1

4.25e-0329672GO:0004629
GeneOntologyMolecularFunctionligand-gated channel activity

GABRP GRIK1 GRIK2 GRIK3

4.34e-03197674GO:0022834
GeneOntologyMolecularFunctionmonoatomic ion channel activity

GABRP NALCN GRIK1 GRIK2 GRIK3 LRRC8D

4.37e-03459676GO:0005216
GeneOntologyMolecularFunctionATP-dependent activity

DNAH3 BRIP1 ATRX DNAH2 KIF14 MYH15 SRPRA

4.43e-03614677GO:0140657
GeneOntologyMolecularFunctionendopeptidase regulator activity

USP14 PTTG3P PTTG1 PTTG2

4.66e-03201674GO:0061135
GeneOntologyMolecularFunctionribonucleoprotein complex binding

PTTG3P PTTG1 SRPRA PTTG2

5.08e-03206674GO:0043021
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC19A3 GRIK1 GRIK2 GRIK3

5.17e-03207674GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC19A3 GRIK1 GRIK2 GRIK3

5.25e-03208674GO:0005342
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

GRIK1 GRIK2 GRIK3

5.30e-03105673GO:0015171
GeneOntologyMolecularFunctionphospholipase activity

ABHD3 PLCB1 PLCL1

6.66e-03114673GO:0004620
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH3 DNAH2

6.85e-0337672GO:0045505
GeneOntologyMolecularFunctionenzyme regulator activity

USP14 PTTG3P PTTG1 TIAM1 SRGAP1 MOB1A PLCB1 PRKAR2A RPGR ARHGAP21 PTTG2

7.20e-0314186711GO:0030234
GeneOntologyBiologicalProcessmitotic sister chromatid cohesion

PDS5B PTTG3P PTTG1 ATRX PTTG2

8.58e-0836645GO:0007064
GeneOntologyBiologicalProcessligand-gated ion channel signaling pathway

TIAM1 PLCB1 GRIK1 GRIK2 GRIK3

1.48e-0740645GO:1990806
GeneOntologyBiologicalProcessglutamate receptor signaling pathway

TIAM1 PLCB1 GRIK1 GRIK2 GRIK3

1.08e-0659645GO:0007215
GeneOntologyBiologicalProcessionotropic glutamate receptor signaling pathway

TIAM1 GRIK1 GRIK2 GRIK3

1.40e-0627644GO:0035235
GeneOntologyBiologicalProcesssister chromatid cohesion

PDS5B PTTG3P PTTG1 ATRX PTTG2

2.04e-0667645GO:0007062
GeneOntologyBiologicalProcessnegative regulation of synaptic transmission, glutamatergic

GRIK1 GRIK2 GRIK3

7.97e-0613643GO:0051967
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

GABRP USP14 DRD1 NALCN PLCB1 PRKAR2A GRIK1 SYNPO GRIK2 GRIK3 PLCL1 CNP

2.50e-059316412GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

GABRP USP14 DRD1 NALCN PLCB1 PRKAR2A GRIK1 SYNPO GRIK2 GRIK3 PLCL1 CNP

2.50e-059316412GO:0007268
GeneOntologyBiologicalProcesstrans-synaptic signaling

GABRP USP14 DRD1 NALCN PLCB1 PRKAR2A GRIK1 SYNPO GRIK2 GRIK3 PLCL1 CNP

2.72e-059396412GO:0099537
GeneOntologyBiologicalProcesssynaptic signaling

GABRP USP14 DRD1 NALCN PLCB1 PRKAR2A GRIK1 SYNPO GRIK2 GRIK3 PLCL1 CNP

3.97e-059766412GO:0099536
GeneOntologyBiologicalProcesshomologous chromosome segregation

PTTG3P PTTG1 BRIP1 PTTG2

1.01e-0478644GO:0045143
GeneOntologyBiologicalProcessnegative regulation of synaptic transmission

DRD1 GRIK1 GRIK2 GRIK3

1.12e-0480644GO:0050805
GeneOntologyBiologicalProcessmeiotic cell cycle process

PTTG3P PTTG1 BRIP1 ATRX PLCB1 PTTG2

1.81e-04268646GO:1903046
GeneOntologyBiologicalProcessregulation of synaptic transmission, glutamatergic

DRD1 GRIK1 GRIK2 GRIK3

1.92e-0492644GO:0051966
GeneOntologyBiologicalProcessmodulation of chemical synaptic transmission

DRD1 NALCN PLCB1 PRKAR2A GRIK1 SYNPO GRIK2 GRIK3 PLCL1

1.97e-04663649GO:0050804
GeneOntologyBiologicalProcessaxon midline choice point recognition

DIAPH2 FOXG1

1.97e-047642GO:0016199
GeneOntologyBiologicalProcessregulation of trans-synaptic signaling

DRD1 NALCN PLCB1 PRKAR2A GRIK1 SYNPO GRIK2 GRIK3 PLCL1

1.99e-04664649GO:0099177
GeneOntologyBiologicalProcessregulation of long-term neuronal synaptic plasticity

GRIK1 SYNPO GRIK2

2.59e-0440643GO:0048169
GeneOntologyBiologicalProcesspostsynaptic modulation of chemical synaptic transmission

DRD1 PLCB1 SYNPO

3.00e-0442643GO:0099170
GeneOntologyBiologicalProcessmodification of postsynaptic structure

DRD1 TIAM1 SYNPO

3.00e-0442643GO:0099010
GeneOntologyBiologicalProcessaxon choice point recognition

DIAPH2 FOXG1

3.36e-049642GO:0016198
GeneOntologyBiologicalProcessregulation of synaptic transmission, GABAergic

NALCN GRIK1 PLCL1

3.68e-0445643GO:0032228
GeneOntologyBiologicalProcessmodification of synaptic structure

DRD1 TIAM1 SYNPO

5.34e-0451643GO:0099563
GeneOntologyBiologicalProcessmeiotic chromosome segregation

PTTG3P PTTG1 BRIP1 PTTG2

5.63e-04122644GO:0045132
GeneOntologyBiologicalProcessmeiotic cell cycle

PTTG3P PTTG1 BRIP1 ATRX PLCB1 PTTG2

7.49e-04350646GO:0051321
GeneOntologyBiologicalProcesssynaptic transmission, glutamatergic

DRD1 GRIK1 GRIK2 GRIK3

7.57e-04132644GO:0035249
GeneOntologyCellularComponentkainate selective glutamate receptor complex

GRIK1 GRIK2 GRIK3

5.97e-076663GO:0032983
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

DNAH3 PTTG3P PTTG1 DNAH2 PRKAR2A DNAI4 GRIK2 GRIK3 PTTG2

6.56e-07317669GO:0032838
GeneOntologyCellularComponentcytoplasmic region

DNAH3 PTTG3P PTTG1 DNAH2 PRKAR2A DNAI4 GRIK2 GRIK3 PTTG2

1.88e-06360669GO:0099568
GeneOntologyCellularComponentaxoneme

DNAH3 PTTG3P PTTG1 DNAH2 PRKAR2A DNAI4 PTTG2

4.01e-06207667GO:0005930
GeneOntologyCellularComponentciliary plasm

DNAH3 PTTG3P PTTG1 DNAH2 PRKAR2A DNAI4 PTTG2

4.13e-06208667GO:0097014
GeneOntologyCellularComponentcilium

FSIP2 DNAH3 PTTG3P PTTG1 DRD1 TIAM1 VCAN DNAH2 PRKAR2A DNAI4 RPGR PTTG2

2.12e-058986612GO:0005929
GeneOntologyCellularComponentaxonemal dynein complex

DNAH3 DNAH2 DNAI4

6.58e-0525663GO:0005858
GeneOntologyCellularComponentsodium channel complex

GRIK1 GRIK2 GRIK3

1.04e-0429663GO:0034706
GeneOntologyCellularComponentionotropic glutamate receptor complex

GRIK1 GRIK2 GRIK3

3.88e-0445663GO:0008328
GeneOntologyCellularComponentinner dynein arm

DNAH3 DNAH2

4.35e-0410662GO:0036156
GeneOntologyCellularComponentneurotransmitter receptor complex

GRIK1 GRIK2 GRIK3

5.30e-0450663GO:0098878
GeneOntologyCellularComponentaxon terminus

DRD1 CDHR3 GRIK1 GRIK2 GRIK3

5.30e-04210665GO:0043679
GeneOntologyCellularComponentdynein complex

DNAH3 DNAH2 DNAI4

6.65e-0454663GO:0030286
GeneOntologyCellularComponentperikaryon

KLHL24 SYNPO GRIK2 GRIK3 PDE11A

6.96e-04223665GO:0043204
GeneOntologyCellularComponentneuron projection terminus

DRD1 CDHR3 GRIK1 GRIK2 GRIK3

8.47e-04233665GO:0044306
GeneOntologyCellularComponentglutamatergic synapse

USP14 DRD1 TIAM1 PLCB1 PRKAR2A GRIK1 SYNPO GRIK2 GRIK3

1.02e-03817669GO:0098978
GeneOntologyCellularComponentsupramolecular fiber

DNAH3 SYNPO2 TIAM1 DNAH2 DIAPH2 KIF14 MYH15 SYNPO CMYA5 CNP AHNAK2

1.08e-0311796611GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

DNAH3 SYNPO2 TIAM1 DNAH2 DIAPH2 KIF14 MYH15 SYNPO CMYA5 CNP AHNAK2

1.14e-0311876611GO:0099081
GeneOntologyCellularComponentneuronal cell body

KLHL24 DRD1 TIAM1 GRIK1 SYNPO GRIK2 GRIK3 CD200 PDE11A

1.19e-03835669GO:0043025
GeneOntologyCellularComponentmonoatomic ion channel complex

GABRP NALCN GRIK1 GRIK2 GRIK3 LRRC8D

1.22e-03378666GO:0034702
GeneOntologyCellularComponentpostsynaptic density membrane

TIAM1 GRIK1 GRIK2 GRIK3

1.54e-03157664GO:0098839
GeneOntologyCellularComponentmicrotubule associated complex

DNAH3 DNAH2 KIF14 DNAI4

1.69e-03161664GO:0005875
GeneOntologyCellularComponentmyofibril

SYNPO2 MYH15 SYNPO CMYA5 AHNAK2

1.71e-03273665GO:0030016
GeneOntologyCellularComponentpostsynaptic membrane

GABRP DRD1 TIAM1 GRIK1 GRIK2 GRIK3

1.74e-03405666GO:0045211
GeneOntologyCellularComponentaxon

KLHL24 DRD1 TIAM1 CDHR3 GRIK1 SYNPO GRIK2 GRIK3 CD200

1.86e-03891669GO:0030424
GeneOntologyCellularComponentcostamere

CMYA5 AHNAK2

2.18e-0322662GO:0043034
GeneOntologyCellularComponentcontractile muscle fiber

SYNPO2 MYH15 SYNPO CMYA5 AHNAK2

2.22e-03290665GO:0043292
GeneOntologyCellularComponentcell body

KLHL24 DRD1 TIAM1 GRIK1 SYNPO GRIK2 GRIK3 CD200 PDE11A

2.48e-03929669GO:0044297
GeneOntologyCellularComponentdistal axon

DRD1 TIAM1 CDHR3 GRIK1 GRIK2 GRIK3

2.49e-03435666GO:0150034
GeneOntologyCellularComponentpostsynaptic density

TIAM1 GRIK1 SYNPO GRIK2 GRIK3 CD200

2.97e-03451666GO:0014069
GeneOntologyCellularComponentnon-motile cilium

DRD1 TIAM1 VCAN RPGR

3.43e-03196664GO:0097730
GeneOntologyCellularComponentterminal bouton

GRIK1 GRIK2 GRIK3

3.48e-0396663GO:0043195
GeneOntologyCellularComponentpostsynaptic specialization membrane

TIAM1 GRIK1 GRIK2 GRIK3

3.76e-03201664GO:0099634
GeneOntologyCellularComponentasymmetric synapse

TIAM1 GRIK1 SYNPO GRIK2 GRIK3 CD200

3.91e-03477666GO:0032279
GeneOntologyCellularComponentpotassium channel complex

GRIK1 GRIK2 GRIK3

4.36e-03104663GO:0034705
GeneOntologyCellularComponentpostsynapse

GABRP DRD1 TIAM1 PLCB1 GRIK1 SYNPO GRIK2 GRIK3 CD200

4.54e-031018669GO:0098794
GeneOntologyCellularComponentpostsynaptic specialization

TIAM1 GRIK1 SYNPO GRIK2 GRIK3 CD200

5.06e-03503666GO:0099572
GeneOntologyCellularComponentmotile cilium

FSIP2 DNAH3 DNAH2 DNAI4 RPGR

5.26e-03355665GO:0031514
GeneOntologyCellularComponentFlemming body

IL16 KIF14

5.77e-0336662GO:0090543
GeneOntologyCellularComponentneuron to neuron synapse

TIAM1 GRIK1 SYNPO GRIK2 GRIK3 CD200

6.09e-03523666GO:0098984
GeneOntologyCellularComponenttransmembrane transporter complex

GABRP NALCN GRIK1 GRIK2 GRIK3 LRRC8D

6.09e-03523666GO:1902495
GeneOntologyCellularComponentdendrite cytoplasm

GRIK2 GRIK3

6.75e-0339662GO:0032839
GeneOntologyCellularComponent9+2 motile cilium

FSIP2 DNAH3 DNAH2 RPGR

6.80e-03238664GO:0097729
GeneOntologyCellularComponenttransporter complex

GABRP NALCN GRIK1 GRIK2 GRIK3 LRRC8D

7.73e-03550666GO:1990351
GeneOntologyCellularComponentsarcomere

SYNPO2 SYNPO CMYA5 AHNAK2

7.95e-03249664GO:0030017
GeneOntologyCellularComponentactin cytoskeleton

SYNPO2 LAD1 DIAPH2 MYH15 SYNPO ARHGAP21

9.58e-03576666GO:0015629
GeneOntologyCellularComponentsynaptic membrane

GABRP DRD1 TIAM1 GRIK1 GRIK2 GRIK3

1.01e-02583666GO:0097060
MousePhenoabsent sperm fibrous sheath

FSIP2 DNAH2 CCDC183

3.55e-068573MP:0030591
MousePhenodecreased pancreatic beta cell proliferation

PTTG3P PTTG1 PTTG2

1.04e-0511573MP:0011820
MousePhenopolyuria

PTTG3P PTTG1 NPR3 REN PTTG2

3.01e-0589575MP:0001762
MousePhenoabnormal pancreatic beta cell proliferation

PTTG3P PTTG1 PTTG2

8.11e-0521573MP:0011818
MousePhenodecreased paired-pulse facilitation

USP14 GRIK2 GRIK3

1.39e-0425573MP:0002920
MousePhenoreduced long-term potentiation

USP14 ATRX SYNPO GRIK2 GRIK3

2.67e-04141575MP:0001473
MousePhenoabnormal long-term potentiation

USP14 ATRX GRIK1 SYNPO GRIK2 GRIK3

2.70e-04221576MP:0002207
MousePhenoabnormal sperm fibrous sheath morphology

FSIP2 DNAH2 CCDC183

2.93e-0432573MP:0030590
MousePhenodecreased pancreatic beta cell mass

PTTG3P PTTG1 PTTG2

2.93e-0432573MP:0009114
MousePhenoabnormal urination

PTTG3P PTTG1 NPR3 REN PTTG2

3.34e-04148575MP:0001756
MousePhenothymus hyperplasia

PTTG3P PTTG1 PTTG2

3.52e-0434573MP:0000708
DomainANF_lig-bd_rcpt

NPR3 GRIK1 GRIK2 GRIK3

7.61e-0637644IPR001828
DomainANF_receptor

NPR3 GRIK1 GRIK2 GRIK3

7.61e-0637644PF01094
DomainPeripla_BP_I

NPR3 GRIK1 GRIK2 GRIK3

9.42e-0639644IPR028082
DomainSecurin_separation-inh_met

PTTG1 PTTG2

1.16e-052642IPR018008
DomainSecurin

PTTG1 PTTG2

1.16e-052642PF04856
DomainSecurin_separation_inhibitor

PTTG1 PTTG2

1.16e-052642IPR006940
DomainIontro_rcpt

GRIK1 GRIK2 GRIK3

3.02e-0518643IPR001320
DomainLig_chan-Glu_bd

GRIK1 GRIK2 GRIK3

3.02e-0518643PF10613
DomainIono_rcpt_met

GRIK1 GRIK2 GRIK3

3.02e-0518643IPR001508
DomainGlu/Gly-bd

GRIK1 GRIK2 GRIK3

3.02e-0518643IPR019594
DomainLig_chan-Glu_bd

GRIK1 GRIK2 GRIK3

3.02e-0518643SM00918
DomainLig_chan

GRIK1 GRIK2 GRIK3

3.02e-0518643PF00060
DomainPBPe

GRIK1 GRIK2 GRIK3

3.02e-0518643SM00079
DomainPDZ

SYNPO2 IL16 TIAM1 ARHGAP21 AHNAK2

1.22e-04141645PF00595
DomainPDZ

SYNPO2 IL16 TIAM1 ARHGAP21 AHNAK2

1.53e-04148645SM00228
Domain-

SYNPO2 IL16 TIAM1 ARHGAP21 AHNAK2

1.63e-041506452.30.42.10
DomainPDZ

SYNPO2 IL16 TIAM1 ARHGAP21 AHNAK2

1.68e-04151645PS50106
DomainPDZ

SYNPO2 IL16 TIAM1 ARHGAP21 AHNAK2

1.73e-04152645IPR001478
DomainDynein_heavy_chain_D4_dom

DNAH3 DNAH2

1.02e-0314642IPR024317
DomainDynein_HC_stalk

DNAH3 DNAH2

1.02e-0314642IPR024743
DomainDynein_heavy_dom-2

DNAH3 DNAH2

1.02e-0314642IPR013602
DomainDHC_N2

DNAH3 DNAH2

1.02e-0314642PF08393
DomainMT

DNAH3 DNAH2

1.02e-0314642PF12777
DomainAAA_8

DNAH3 DNAH2

1.02e-0314642PF12780
DomainATPase_dyneun-rel_AAA

DNAH3 DNAH2

1.02e-0314642IPR011704
DomainAAA_5

DNAH3 DNAH2

1.02e-0314642PF07728
DomainDHC_fam

DNAH3 DNAH2

1.18e-0315642IPR026983
DomainPLipase_C_Pinositol-sp_Y

PLCB1 PLCL1

1.18e-0315642IPR001711
DomainEF-hand_like

PLCB1 PLCL1

1.18e-0315642PF09279
DomainPIPLC_Y_DOMAIN

PLCB1 PLCL1

1.18e-0315642PS50008
DomainDynein_heavy_dom

DNAH3 DNAH2

1.18e-0315642IPR004273
DomainPI-PLC_fam

PLCB1 PLCL1

1.18e-0315642IPR001192
DomainPLC_EF-hand-like

PLCB1 PLCL1

1.18e-0315642IPR015359
DomainPI-PLC-Y

PLCB1 PLCL1

1.18e-0315642PF00387
DomainPLCYc

PLCB1 PLCL1

1.18e-0315642SM00149
DomainDynein_heavy

DNAH3 DNAH2

1.18e-0315642PF03028
DomainPI-PLC-X

PLCB1 PLCL1

1.71e-0318642PF00388
DomainPLCXc

PLCB1 PLCL1

1.71e-0318642SM00148
DomainPIPLC_X_DOMAIN

PLCB1 PLCL1

1.90e-0319642PS50007
DomainPLipase_C_PInositol-sp_X_dom

PLCB1 PLCL1

1.90e-0319642IPR000909
Domain-

PLCB1 PLCL1

3.30e-03256423.20.20.190
DomainPLC-like_Pdiesterase_TIM-brl

PLCB1 PLCL1

3.30e-0325642IPR017946
DomainP-loop_NTPase

DNAH3 BRIP1 ATRX DNAH2 KIF14 MYH15 SRPRA CNP

8.16e-03848648IPR027417
PathwayREACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING

PLCB1 GRIK1 GRIK2 GRIK3

3.04e-0630484M18193
PathwayREACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING

PLCB1 GRIK1 GRIK2 GRIK3

3.97e-0632484MM15143
PathwayREACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS

GRIK1 GRIK2 GRIK3

4.37e-0610483M10272
PathwayWP_NEUROINFLAMMATION_AND_GLUTAMATERGIC_SIGNALING

PLCB1 SHMT1 GRIK1 GRIK2 GRIK3 LRRC8D

7.50e-06140486M42572
PathwayREACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS

GRIK1 GRIK2 GRIK3

7.98e-0612483MM15142
PathwayBIOCARTA_CK1_PATHWAY

DRD1 PLCB1 PRKAR2A

1.64e-0515483MM1468
PathwayBIOCARTA_CK1_PATHWAY

DRD1 PLCB1 PRKAR2A

2.01e-0516483M16626
PathwayREACTOME_SEPARATION_OF_SISTER_CHROMATIDS

PDS5B PTTG3P PTTG1 NUP85 PTTG2

4.85e-04193485MM14890
Pubmed

Mice lacking pituitary tumor transforming gene show testicular and splenic hypoplasia, thymic hyperplasia, thrombocytopenia, aberrant cell cycle progression, and premature centromere division.

PTTG3P PTTG1 PTTG2

7.15e-09368311682618
Pubmed

PTTG is a secretory protein in human pituitary adenomas and in mouse pituitary tumor cell lines.

PTTG3P PTTG1 PTTG2

7.15e-09368317652795
Pubmed

Pituitary Tumor Transforming Gene 1 Orchestrates Gene Regulatory Variation in Mouse Ventral Midbrain During Aging.

PTTG3P PTTG1 PTTG2

7.15e-09368333173537
Pubmed

PTTG1 Reprograms Asparagine Metabolism to Promote Hepatocellular Carcinoma Progression.

PTTG3P PTTG1 PTTG2

7.15e-09368337159932
Pubmed

Pttg1/securin is required for the branching morphogenesis of the mammary gland and suppresses mammary tumorigenesis.

PTTG3P PTTG1 PTTG2

7.15e-09368324395789
Pubmed

The lifespan quantitative trait locus gene Securin controls hematopoietic progenitor cell function.

PTTG3P PTTG1 PTTG2

7.15e-09368331073078
Pubmed

A prometaphase mechanism of securin destruction is essential for meiotic progression in mouse oocytes.

PTTG3P PTTG1 PTTG2

7.15e-09368334262048
Pubmed

Pituitary tumor transforming gene as a novel regulatory factor of liver fibrosis.

PTTG3P PTTG1 PTTG2

7.15e-09368325936962
Pubmed

Mad2 is required for inhibiting securin and cyclin B degradation following spindle depolymerisation in meiosis I mouse oocytes.

PTTG3P PTTG1 PTTG2

7.15e-09368316322543
Pubmed

PTTG1 alleviates acute alcoholic liver injury by inhibiting endoplasmic reticulum stress-induced hepatocyte pyroptosis.

PTTG3P PTTG1 PTTG2

7.15e-09368336737842
Pubmed

Discordant proliferation and differentiation in pituitary tumor-transforming gene-null bone marrow stem cells.

PTTG3P PTTG1 PTTG2

7.15e-09368317626243
Pubmed

Pituitary tumor transforming gene: an update.

PTTG3P PTTG1 PTTG2

7.15e-09368315281346
Pubmed

Pituitary senescence: the evolving role of Pttg.

PTTG3P PTTG1 PTTG2

7.15e-09368320153804
Pubmed

Securin and not CDK1/cyclin B1 regulates sister chromatid disjunction during meiosis II in mouse eggs.

PTTG3P PTTG1 PTTG2

7.15e-09368318639540
Pubmed

Kainate receptor-mediated responses in the CA1 field of wild-type and GluR6-deficient mice.

GRIK1 GRIK2 GRIK3

7.15e-0936839880586
Pubmed

The kainate receptor antagonist UBP310 but not single deletion of GluK1, GluK2, or GluK3 subunits, inhibits MPTP-induced degeneration in the mouse midbrain.

GRIK1 GRIK2 GRIK3

7.15e-09368331513786
Pubmed

Pituitary tumor transforming gene (PTTG) transforming and transactivation activity.

PTTG3P PTTG1 PTTG2

7.15e-09368310713046
Pubmed

Pituitary tumor transforming gene-null male mice exhibit impaired pancreatic beta cell proliferation and diabetes.

PTTG3P PTTG1 PTTG2

7.15e-09368312626748
Pubmed

Differential trafficking of GluR7 kainate receptor subunit splice variants.

GRIK1 GRIK2 GRIK3

7.15e-09368315805114
Pubmed

Maternal age-dependent APC/C-mediated decrease in securin causes premature sister chromatid separation in meiosis II.

PTTG3P PTTG1 PTTG2

7.15e-09368328516917
Pubmed

Sex-steroid milieu determines diabetes rescue in pttg-null mice.

PTTG3P PTTG1 PTTG2

7.15e-09368316731783
Pubmed

Mechanisms for growth factor-induced pituitary tumor transforming gene-1 expression in pituitary folliculostellate TtT/GF cells.

PTTG3P PTTG1 PTTG2

7.15e-09368316959877
Pubmed

Characterization of the murine pituitary tumor transforming gene (PTTG) and its promoter.

PTTG3P PTTG1 PTTG2

7.15e-09368310650958
Pubmed

Regulation of pituitary tumor transforming gene (PTTG) expression and phosphorylation in thyroid cells.

PTTG3P PTTG1 PTTG2

7.15e-09368323867215
Pubmed

Characterization of the pituitary tumor transforming gene 1 knockout mouse retina.

PTTG3P PTTG1 PTTG2

7.15e-09368321203837
Pubmed

Murine pituitary tumor-transforming gene functions as a securin protein in insulin-secreting cells.

PTTG3P PTTG1 PTTG2

7.15e-09368317065388
Pubmed

Pituitary hypoplasia in Pttg-/- mice is protective for Rb+/- pituitary tumorigenesis.

PTTG3P PTTG1 PTTG2

2.86e-08468315919720
Pubmed

Anaphase B precedes anaphase A in the mouse egg.

PTTG3P PTTG1 PTTG2

2.86e-08468322342753
Pubmed

Securin and separase phosphorylation act redundantly to maintain sister chromatid cohesion in mammalian cells.

PTTG3P PTTG1 PTTG2

2.86e-08468316030258
Pubmed

Degradation of securin in mouse and pig oocytes is dependent on ubiquitin-proteasome pathway and is required for proteolysis of the cohesion subunit, Rec8, at the metaphase-to-anaphase transition.

PTTG3P PTTG1 PTTG2

2.86e-08468316720305
Pubmed

The pituitary tumor-transforming gene promotes angiogenesis in a mouse model of follicular thyroid cancer.

PTTG3P PTTG1 PTTG2

2.86e-08468317127711
Pubmed

Tumor suppressor activity of KLF6 mediated by downregulation of the PTTG1 oncogene.

PTTG3P PTTG1 PTTG2

2.86e-08468320116377
Pubmed

Pituitary tumor transforming gene 1 induces tumor necrosis factor-α production from keratinocytes: implication for involvement in the pathophysiology of psoriasis.

PTTG3P PTTG1 PTTG2

2.86e-08468323677169
Pubmed

Preimplantation mouse embryos depend on inhibitory phosphorylation of separase to prevent chromosome missegregation.

PTTG3P PTTG1 PTTG2

2.86e-08468319124608
Pubmed

Induction of Dlk1 by PTTG1 inhibits adipocyte differentiation and correlates with malignant transformation.

PTTG3P PTTG1 PTTG2

2.86e-08468319477929
Pubmed

The pituitary tumour-transforming gene 1/delta-like homologue 1 pathway plays a key role in liver fibrogenesis.

PTTG3P PTTG1 PTTG2

2.86e-08468335050550
Pubmed

Securin is not required for cellular viability, but is required for normal growth of mouse embryonic fibroblasts.

PTTG3P PTTG1 PTTG2

2.86e-08468311516952
Pubmed

Kainate receptors and rhythmic activity in neuronal networks: hippocampal gamma oscillations as a tool.

GRIK1 GRIK2 GRIK3

2.86e-08468315513934
Pubmed

Tumorigenic potential of pituitary tumor transforming gene (PTTG) in vivo investigated using a transgenic mouse model, and effects of cross breeding with p53 (+/-) transgenic mice.

PTTG3P PTTG1 PTTG2

2.86e-08468323164239
Pubmed

Abnormal megakaryocyte development and platelet function in Nbeal2(-/-) mice.

PTTG3P PTTG1 PTTG2

2.86e-08468323861251
Pubmed

Spatial learning and long-term memory impairments in RasGrf1 KO, Pttg1 KO, and double KO mice.

PTTG3P PTTG1 PTTG2

2.86e-08468330259712
Pubmed

Reduced synaptic function of Kainate receptors in the insular cortex of Fmr1 Knock-out mice.

GRIK1 GRIK2 GRIK3

2.86e-08468330241548
Pubmed

Expression of PTTG and prc1 genes during telencephalic neurogenesis.

PTTG3P PTTG1 PTTG2

2.86e-08468310727870
Pubmed

Pituitary tumor-transforming gene 1 regulates the patterning of retinal mosaics.

PTTG3P PTTG1 PTTG2

2.86e-08468324927528
Pubmed

The selective continued linkage of centromeres from mitosis to interphase in the absence of mammalian separase.

PTTG3P PTTG1 PTTG2

2.86e-08468316533944
Pubmed

Separase: a universal trigger for sister chromatid disjunction but not chromosome cycle progression.

PTTG3P PTTG1 PTTG2

2.86e-08468316533945
Pubmed

Aberrant accumulation of PTTG1 induced by a mutated thyroid hormone beta receptor inhibits mitotic progression.

PTTG3P PTTG1 PTTG2

2.86e-08468317039256
Pubmed

Transcriptional profiling reveals functional links between RasGrf1 and Pttg1 in pancreatic beta cells.

PTTG3P PTTG1 PTTG2

2.86e-08468325421944
Pubmed

Kainate receptors act as conditional amplifiers of spike transmission at hippocampal mossy fiber synapses.

GRIK1 GRIK2 GRIK3

2.86e-08468319369569
Pubmed

A single amino acid substitution (Cys249Trp) in Crb1 causes retinal degeneration and deregulates expression of pituitary tumor transforming gene Pttg1.

PTTG3P PTTG1 PTTG2

2.86e-08468317234588
Pubmed

Homologue disjunction in mouse oocytes requires proteolysis of securin and cyclin B1.

PTTG3P PTTG1 PTTG2

2.86e-08468314593421
Pubmed

Securin regulates entry into M-phase by modulating the stability of cyclin B.

PTTG3P PTTG1 PTTG2

2.86e-08468318364698
Pubmed

Glypican-1 regulates anaphase promoting complex/cyclosome substrates and cell cycle progression in endothelial cells.

PTTG3P PTTG1 PTTG2

2.86e-08468318417614
Pubmed

Developmental expression patterns of kainate receptors in the mouse spinal cord.

GRIK1 GRIK2 GRIK3

7.13e-08568323076118
Pubmed

p21(Cip1) restrains pituitary tumor growth.

PTTG3P PTTG1 PTTG2

7.13e-08568318981426
Pubmed

Complete Disruption of the Kainate Receptor Gene Family Results in Corticostriatal Dysfunction in Mice.

GRIK1 GRIK2 GRIK3

7.13e-08568328228252
Pubmed

MEIKIN expression and its C-terminal phosphorylation by PLK1 is closely related the metaphase-anaphase transition by affecting cyclin B1 and Securin stabilization in meiotic oocyte.

PTTG3P PTTG1 PTTG2

7.13e-08568339093409
Pubmed

Targeting mitotic exit leads to tumor regression in vivo: Modulation by Cdk1, Mastl, and the PP2A/B55α,δ phosphatase.

PTTG3P PTTG1 PTTG2

7.13e-08568321156286
Pubmed

PTTG-binding factor (PBF) is a novel regulator of the thyroid hormone transporter MCT8.

PTTG3P PTTG1 PTTG2

7.13e-08568322535767
Pubmed

Development of laminar distributions of kainate receptors in the somatosensory cortex of mice.

GRIK1 GRIK2 GRIK3

7.13e-0856839593973
Pubmed

Smurf1 targets Securin for ubiquitin-dependent degradation and regulates the metaphase-to-anaphase transition.

PTTG3P PTTG1 PTTG2

7.13e-08568328658604
Pubmed

Senescence mediates pituitary hypoplasia and restrains pituitary tumor growth.

PTTG3P PTTG1 PTTG2

7.13e-08568317975001
Pubmed

Kainate receptors: pharmacology, function and therapeutic potential.

GRIK1 GRIK2 GRIK3

7.13e-08568318793656
Pubmed

The meiosis I-to-meiosis II transition in mouse oocytes requires separase activity.

PTTG3P PTTG1 PTTG2

7.13e-08568314561405
Pubmed

Kainate receptor subunits underlying presynaptic regulation of transmitter release in the dorsal horn.

GRIK1 GRIK2 GRIK3

7.13e-08568312223554
Pubmed

Molecular determinants of kainate receptor trafficking.

GRIK1 GRIK2 GRIK3

7.13e-08568318358623
Pubmed

Preferential assembly of heteromeric kainate and AMPA receptor amino terminal domains.

GRIK1 GRIK2 GRIK3

7.13e-08568329058671
Pubmed

The Rae1-Nup98 complex prevents aneuploidy by inhibiting securin degradation.

PTTG3P PTTG1 PTTG2

7.13e-08568316355229
Pubmed

Altered expression of securin (Pttg1) and serpina3n in the auditory system of hearing-impaired Tff3-deficient mice.

PTTG3P PTTG1 PTTG2

7.13e-08568321076990
Pubmed

Involvement of histone deacetylase 1/2 in adrenocorticotropic hormone synthesis and proliferation of corticotroph tumor AtT-20 cells.

PTTG3P PTTG1 PTTG2

1.42e-07668333181265
Pubmed

N-glycan content modulates kainate receptor functional properties.

GRIK1 GRIK2 GRIK3

1.42e-07668328714086
Pubmed

mTOR promotes pituitary tumor development through activation of PTTG1.

PTTG3P PTTG1 PTTG2

1.42e-07668327524416
Pubmed

Function of COP9 signalosome in regulation of mouse oocytes meiosis by regulating MPF activity and securing degradation.

PTTG3P PTTG1 PTTG2

1.42e-07668321991377
Pubmed

Short-term plasticity of kainate receptor-mediated EPSCs induced by NMDA receptors at hippocampal mossy fiber synapses.

GRIK1 GRIK2 GRIK3

2.49e-07768317428973
Pubmed

Loss of Cdc20 causes a securin-dependent metaphase arrest in two-cell mouse embryos.

PTTG3P PTTG1 PTTG2

2.49e-07768317325031
Pubmed

Glutamate receptors in cortical plasticity: molecular and cellular biology.

GRIK1 GRIK2 GRIK3

2.49e-0776839016303
Pubmed

Glutamate binding and conformational flexibility of ligand-binding domains are critical early determinants of efficient kainate receptor biogenesis.

GRIK1 GRIK2 GRIK3

2.49e-07768319342380
Pubmed

Glutamate receptors: brain function and signal transduction.

GRIK1 GRIK2 GRIK3

2.49e-0776839651535
Pubmed

Primary structure and expression of the gamma 2 subunit of the glutamate receptor channel selective for kainate.

GRIK1 GRIK2 GRIK3

2.49e-0776831310861
Pubmed

Transmembrane topology of the glutamate receptor subunit GluR6.

GRIK1 GRIK2 GRIK3

3.98e-0786838163463
Pubmed

Identification of disease-relevant modulators of the SHH pathway in the developing brain.

PTTG3P PTTG1 PTTG2

5.95e-07968334463328
Pubmed

Expression of glutamate receptor subunit genes during development of the mouse retina.

GRIK1 GRIK2 GRIK3

5.95e-0796839051806
Pubmed

Nuclear pore protein NUP88 activates anaphase-promoting complex to promote aneuploidy.

PTTG3P PTTG1 PTTG2

8.49e-071068326731471
Pubmed

Separase phosphosite mutation leads to genome instability and primordial germ cell depletion during oogenesis.

PTTG3P PTTG1 PTTG2

1.17e-061168321494564
Pubmed

Specificity and Redundancy of Profilin 1 and 2 Function in Brain Development and Neuronal Structure.

PTTG3P PTTG1 PTTG2

2.02e-061368334571959
Pubmed

Diminished pancreatic beta-cell mass in securin-null mice is caused by beta-cell apoptosis and senescence.

PTTG3P PTTG1 PTTG2

2.02e-061368319213844
Pubmed

Glutamatergic gene variants impact the clinical profile of efficacy and side effects of haloperidol.

GRIK1 GRIK2 GRIK3

2.02e-061368320859245
Pubmed

Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.

GABRP NPR3 DRD1 SHMT1 GRIK1 GRIK2 GRIK3

2.05e-0630068719086053
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

PDS5B PTTG3P PTTG1 GTF2I NUP85 RRP12 MOB1A PRKAR2A KIF14 PLK4 PTTG2 BAP1

2.23e-061155681220360068
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

PRRC2C DIAPH2 PLCB1 PRKAR2A SYNPO GRIK2 GRIK3 PLCL1 ARHGAP21 FOXG1 CNP

2.51e-06963681128671696
Pubmed

TIF1β association with HP1 is essential for post-gastrulation development, but not for Sertoli cell functions during spermatogenesis.

PTTG3P PTTG1 PTTG2

3.20e-061568321163256
Pubmed

Presynaptic kainate receptors impart an associative property to hippocampal mossy fiber long-term potentiation.

GRIK1 GRIK2

3.77e-06268212947409
Pubmed

Altered behavioral responses to noxious stimuli and fear in glutamate receptor 5 (GluR5)- or GluR6-deficient mice.

GRIK1 GRIK2

3.77e-06268215673679
Pubmed

Association of markers in the 3' region of the GluR5 kainate receptor subunit gene to alcohol dependence.

GRIK1 GRIK3

3.77e-06268219320626
Pubmed

D1 dopamine receptor coupling to PLCβ regulates forward locomotion in mice.

DRD1 PLCB1

3.77e-06268224227722
Pubmed

Gene signatures and prognostic analyses of the Tob/BTG pituitary tumor-transforming gene (PTTG) family in clinical breast cancer patients.

PTTG3P PTTG1

3.77e-06268233173433
Pubmed

Kainate receptors are involved in short- and long-term plasticity at mossy fiber synapses in the hippocampus.

GRIK1 GRIK2

3.77e-06268211182092
Pubmed

Kainate receptor-mediated synaptic transmission in the adult anterior cingulate cortex.

GRIK1 GRIK2

3.77e-06268215928066
Pubmed

Modulation of excitatory synaptic transmission in the spinal substantia gelatinosa of mice deficient in the kainate receptor GluR5 and/or GluR6 subunit.

GRIK1 GRIK2

3.77e-06268214724198
Pubmed

GluR7 is an essential subunit of presynaptic kainate autoreceptors at hippocampal mossy fiber synapses.

GRIK2 GRIK3

3.77e-06268217620617
InteractionPRPS2 interactions

PDS5B USP14 BRIP1 GTF2I SRGAP1 SHMT1 KIF14 BAP1

1.69e-06253668int:PRPS2
InteractionGRIK4 interactions

GRIK1 GRIK2 GRIK3

1.86e-068663int:GRIK4
InteractionGRIK2 interactions

KLHL24 GRIK1 GRIK2 GRIK3

3.52e-0632664int:GRIK2
InteractionGRIK3 interactions

GRIK1 GRIK2 GRIK3

3.96e-0610663int:GRIK3
InteractionCCDC15 interactions

TIAM1 PLK4 TRIM44

7.23e-0612663int:CCDC15
InteractionFLNA interactions

USP14 SYNPO2 DRD1 LAD1 KIF14 GRIK1 SYNPO GRIK3 TRIM44 ARHGAP21 BAP1

7.51e-066486611int:FLNA
InteractionPCNT interactions

GTF2I CCDC18 PRKAR2A KIF14 CCDC183 PLK4 ARHGAP21

1.37e-05241667int:PCNT
InteractionGRIK5 interactions

GRIK1 GRIK2 GRIK3

3.68e-0520663int:GRIK5
InteractionSMC3 interactions

PDS5B ATRX ANKRD11 KIF14 SRPRA RPGR FOXG1 BAP1

5.42e-05408668int:SMC3
InteractionHAPSTR1 interactions

PDS5B GTF2I NUP85 ATRX PRRC2C RRP12 PLCB1 SHMT1 KIF14 SYNPO BAP1

7.24e-058296611int:HAPSTR1
InteractionWDR1 interactions

USP14 ATRX KIF14 SYNPO PLK4 BAP1

8.32e-05220666int:WDR1
InteractionRHOA interactions

SYNPO2 NUP85 TIAM1 SRGAP1 RRP12 DIAPH2 KIF14 SRPRA RPGR LRRC8D ARHGAP21 CNP BAP1

1.17e-0411996613int:RHOA
Cytoband5q35.1

GABRP PTTG1 DRD1

2.53e-05386835q35.1
Cytoband11p13

PRRG4 TRIM44

3.16e-035668211p13
Cytoband21q22.11

TIAM1 GRIK1

3.86e-036268221q22.11
CytobandEnsembl 112 genes in cytogenetic band chr11p13

PRRG4 TRIM44

4.23e-0365682chr11p13
GeneFamilyGlutamate ionotropic receptor kainate type subunits

GRIK1 GRIK2 GRIK3

1.34e-0754431199
GeneFamilyPDZ domain containing

SYNPO2 IL16 TIAM1 ARHGAP21 AHNAK2

3.28e-051524451220
GeneFamilyDyneins, axonemal

DNAH3 DNAH2

7.69e-0417442536
GeneFamilyPhospholipases|C2 domain containing phospholipases

PLCB1 PLCL1

9.64e-0419442832
GeneFamilyRho GTPase activating proteins|BCH domain containing

SRGAP1 ARHGAP21

6.58e-0350442721
CoexpressionGSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_UP

PADI4 RRP12 ABHD3 PRRG4 RPGR PTTG2

1.24e-05197686M5347
CoexpressionLIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_QTL

PTTG3P PTTG1 PTTG2

1.57e-0519683MM848
CoexpressionGOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP

PTTG3P PTTG1 NUP85 VCAN RRP12 CCDC18 SHMT1 PLK4 PTTG2

2.31e-05597689MM1309
CoexpressionSHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6

PTTG3P PTTG1 BRIP1 MOB1A KIF14 PLK4 FOXG1 PTTG2

2.41e-05458688M8520
CoexpressionHE_LIM_SUN_FETAL_LUNG_C5_PRO_B_CELL

PDS5B PTTG1 BRIP1 ABHD3 PLCB1 SHMT1 KIF14 PLK4

3.27e-05478688M45785
CoexpressionVIETOR_IFRD1_TARGETS

PTTG3P PTTG1 PTTG2

4.67e-0527683MM655
CoexpressionMCBRYAN_PUBERTAL_BREAST_6_7WK_DN

PTTG3P PTTG1 VCAN PTTG2

7.84e-0587684MM992
CoexpressionCEBALLOS_TARGETS_OF_TP53_AND_MYC_DN

ATRX KIF14 REN

8.62e-0533683M1252
CoexpressionLIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_SMALL_VS_HUGE_DN

PTTG3P PTTG1 PTTG2

1.03e-0435683MM542
CoexpressionKINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP

PDS5B PTTG3P PTTG1 BRIP1 NUP85 ANKRD13C ABHD3 SHMT1 KIF14 GRIK2 FSBP PLK4

1.08e-0412906812M80
CoexpressionCROONQUIST_IL6_DEPRIVATION_DN

PTTG1 RRP12 KIF14 PLK4

1.10e-0495684M18506
CoexpressionBERENJENO_TRANSFORMED_BY_RHOA_UP

USP14 PTTG3P PTTG1 NUP85 RRP12 SHMT1 PLK4 PTTG2

1.13e-04571688MM1100
CoexpressionGSE3982_NKCELL_VS_TH1_UP

NPR3 DNAH2 PRKAR2A GRIK3 TRIM44

1.54e-04195685M5593
CoexpressionGSE37534_UNTREATED_VS_GW1929_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN

VCAN ABHD3 KIF14 LRRC8D PLK4

1.70e-04199685M8979
CoexpressionGSE43955_10H_VS_30H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN

KLHL24 NYNRIN SRPRA SYNPO REN

1.70e-04199685M9697
CoexpressionGSE7460_CD8_TCELL_VS_TREG_ACT_DN

PDS5B TIAM1 ANKRD13C LRRC8D TRIM44

1.70e-04199685M5684
CoexpressionGSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_BM_UP

PTTG1 KLHL24 IL16 ATRX CD200

1.74e-04200685M8090
CoexpressionGSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_IFNAR_KO_DN

TIAM1 LAD1 SYNPO LRRC8D CD200

1.74e-04200685M2930
CoexpressionHALLMARK_G2M_CHECKPOINT

PDS5B PTTG3P PTTG1 ATRX PLK4

1.74e-04200685M5901
CoexpressionGSE2770_IL4_ACT_VS_ACT_CD4_TCELL_2H_DN

GABRP KLHL24 PLCL1 TRIM44 CD200

1.74e-04200685M6095
CoexpressionTOYOTA_TARGETS_OF_MIR34B_AND_MIR34C

USP14 BRIP1 GTF2I SHMT1 KIF14 PRRG4 PLK4

1.74e-04454687M19927
CoexpressionCHESLER_BRAIN_HIGHEST_GENETIC_VARIANCE

PTTG3P PTTG1 PTTG2

1.78e-0442683MM617
CoexpressionHU_GENOTOXIC_DAMAGE_4HR

PTTG3P PTTG1 PTTG2

1.91e-0443683MM1204
CoexpressionMANALO_HYPOXIA_UP

GABRP NYNRIN DIAPH2 SYNPO CD200

1.95e-04205685M259
CoexpressionMENON_FETAL_KIDNEY_4_PODOCYTES

PRRC2C SRGAP1 ANKRD11 SYNPO CMYA5

1.99e-04206685M39254
CoexpressionDODD_NASOPHARYNGEAL_CARCINOMA_UP

USP14 PTTG3P PTTG1 SYNPO2 BRIP1 NUP85 PRRC2C VCAN CCDC18 KIF14 PLK4 CD200

2.43e-0414076812M14427
CoexpressionLIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_LARGE_VS_TINY_UP

PTTG3P PTTG1 PTTG2

2.50e-0447683MM539
CoexpressionBLUM_RESPONSE_TO_SALIRASIB_DN

PTTG3P PTTG1 GTF2I SHMT1 PLK4 FOXG1

2.58e-04341686M2879
CoexpressionBURTON_ADIPOGENESIS_PEAK_AT_24HR

PTTG3P PTTG1 PTTG2

2.66e-0448683MM1181
CoexpressionYAGI_AML_WITH_11Q23_REARRANGED

NPR3 ABHD3 GRIK2 RPGR TRIM44 BAP1

2.79e-04346686M17123
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#4_top-relative-expression-ranked_1000

NPR3 ATRX NALCN PRRC2C DIAPH2 GRIK1 PLCL1

1.45e-05256667gudmap_developingGonad_e14.5_ epididymis_1000_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_1000

PDS5B KLHL24 SYNPO2 GTF2I ATRX NALCN PRRC2C VCAN MOB1A PLCB1 TRIM44

4.02e-058186611DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_1000
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Intermediate|2m / Sample Type, Dataset, Time_group, and Cell type.

GTF2I SRGAP1 VCAN GRIK3 ARHGAP21 FOXG1 CD200

2.38e-082006872a635694844ddabcd98462c5636a6f41a3f08a46
ToppCellPBMC-Control-cDC_10|Control / Compartment, Disease Groups and Clusters

SYNPO2 SRGAP1 LAD1 SYNPO PLCL1 CD200

3.95e-071856864b5a7450fed912f340da16065c1e65d626dbe8d1
ToppCellILEUM-inflamed-(3)_MNP-(3)_mature_DC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SYNPO2 LAD1 PRRG4 SYNPO ARHGAP21 CD200

5.06e-07193686d9be4d1de863fffc2240d6fd1a2f8dfb2d2bc916
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

PTTG1 BRIP1 KIF14 PRRG4 PLK4 PTTG2

6.05e-0719968688d130e2451e61afb710edf552e6b346b9fcfb2b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTTG1 CCDC18 KIF14 MYH15 PLK4

5.40e-06165685eec2d327c94832d1390314c93ef6a2be4648478b
ToppCellLA-16._Neuronal|World / Chamber and Cluster_Paper

PLCB1 PRRG4 GRIK2 GRIK3 RPGR

5.89e-061686852fd1fd2a16ac1c5eb028f93cc3a2477c7747693e
ToppCellLA-16._Neuronal|LA / Chamber and Cluster_Paper

PRRG4 GRIK2 GRIK3 RPGR CNP

5.89e-06168685c55bbfbde8bb954f1cb9af82007bdd1f8070fee3
ToppCellLV-16._Neuronal|LV / Chamber and Cluster_Paper

PLCB1 PRRG4 GRIK2 GRIK3 RPGR

6.07e-06169685a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCell(7)_MNP-(7)_DC_activated|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)

SYNPO2 LAD1 SYNPO ARHGAP21 CD200

6.24e-061706854ab495b38a071fa8207331df2ce0d78a2dcd034e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 BRIP1 VCAN MYH15 PLK4

6.42e-06171685b0373ed8283ee1792b6a490bff93906546978593
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 BRIP1 VCAN MYH15 PLK4

6.42e-06171685b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NYNRIN PLCB1 PLCL1 CCDC183 CNP

6.80e-061736857a3115e7cf7e2f345192cde0656a7f0193594a5f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTTG1 BRIP1 CCDC18 KIF14 PLK4

6.99e-06174685dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTTG1 CCDC18 KIF14 GRIK2 PLK4

8.69e-06182685336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BRIP1 CCDC18 KIF14 FSBP FOXG1

9.17e-061846851edefa2a049d7e22d0bdb1ea3d7ef1c8d6ae0fe3
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-Proliferating_T_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BRIP1 CCDC18 KIF14 FSBP FOXG1

9.17e-061846858578c50eaa8ce1cefc0228185c66c8e25f4bfc32
ToppCellCOVID-19-Endothelial_cells-Arterial_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

GABRP NPR3 PLCB1 SYNPO RPGR

9.17e-061846850f19494789f38ab1a420545e15e748ca7eb345c3
ToppCell(7)_DC_activated|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

SYNPO2 SRGAP1 LAD1 SYNPO ARHGAP21

9.17e-06184685b89871a3e36fde6daa68daf116f8c8d587554c0f
ToppCellControl-T_cells-Cycling_NK/T_cells|Control / group, cell type (main and fine annotations)

PTTG1 BRIP1 CCDC18 KIF14 PLK4

9.41e-061856859766216b41ee62bbac4caa25cb98ec5627a24075
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PRRC2C SRGAP1 VCAN DIAPH2 MYH15

9.66e-0618668523b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTTG1 BRIP1 CCDC18 KIF14 PLK4

9.91e-061876859351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 CCDC18 KIF14 GRIK2 PLK4

9.91e-06187685057569c9437219ecc396aa6e673b1178a2273837
ToppCellCiliated_cells-B-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

DNAH3 CDHR3 DNAH2 DNAI4 AHNAK2

1.02e-05188685606907c865bd2f11bb6474932716550f7723d858
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTTG1 BRIP1 CCDC18 KIF14 PLK4

1.18e-051946851a2090e997c70433d07f56bf7cb0a50c4151118c
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDS5B ATRX PRRC2C CCDC18 CNP

1.18e-051946858ef0b71fef5b84cfd04973f891215333e7035d1d
ToppCellcontrol-Lymphocytic-Prol._cells|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

PTTG3P PTTG1 BRIP1 KIF14 PLK4

1.18e-051946854c76508de3291c952386caffda2d559629ba5998
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PTTG1 BRIP1 CCDC18 KIF14 PLK4

1.21e-05195685926eb3fc5d028be936885bea0654a77db3107234
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTTG1 BRIP1 CCDC18 KIF14 PLK4

1.21e-0519568575759fd7f925725f0ecd07214afcca5aa2158f9e
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 CDHR3 DNAH2 DIAPH2 DNAI4

1.21e-051956853486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38|World / Primary Cells by Cluster

GTF2I ATRX PLCB1 ARHGAP21 FOXG1

1.24e-0519668538da0751941adca650fe9b383d9f343153978eb5
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn|World / Primary Cells by Cluster

GTF2I ATRX PLCB1 ARHGAP21 FOXG1

1.24e-05196685721650a08d260faf530dbd52d4e9275d27f3bac2
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PTTG1 BRIP1 CCDC18 KIF14 PLK4

1.24e-0519668573f951f7712e0aa3323676b9a4b7944d21d347c4
ToppCellcontrol-Lymphocytic-Prol._cells|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

PTTG3P PTTG1 BRIP1 KIF14 PLK4

1.24e-05196685886f7c865b086d6ebb4a1746865c30af6bbed345
ToppCellHealthy-T/NK_proliferative|World / disease group, cell group and cell class

PTTG1 BRIP1 SHMT1 KIF14 PLK4

1.27e-05197685e90be1e7e02f736b6aab14010a912b592d6f1e80
ToppCellBAL-Mild-cDC_10|Mild / Compartment, Disease Groups and Clusters

CDHR3 LAD1 SYNPO PLCL1 CD200

1.27e-05197685c0550d41dd5619b369b590f3d6a61154dd7b2cab
ToppCellT_cells-Treg_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

IL16 TIAM1 PLCL1 LRRC8D CD200

1.27e-05197685de5448fcdf4e433fc167496413abe5d0c8a5c6d8
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SYNPO2 NALCN CDHR3 VCAN PLCB1

1.27e-051976856d0d68d460243a0259ada93ebda40fa7b3088eeb
ToppCellHealthy_donor-T/NK_proliferative|Healthy_donor / disease group, cell group and cell class (v2)

PTTG1 BRIP1 SHMT1 KIF14 PLK4

1.27e-05197685b6bbf87e5823fa66b4cad6a7be4f777356887b59
ToppCell(5)_Dendritic_cell-(53)_Lymphoid_DC|(5)_Dendritic_cell / shred on Cell_type and subtype

SYNPO2 SRGAP1 LAD1 ARHGAP21 CD200

1.31e-05198685548da5fa86f9756c503ed77bcdde55bc4d1a2726
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 CDHR3 DNAH2 DIAPH2 DNAI4

1.31e-05198685ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-35|World / Primary Cells by Cluster

GTF2I ATRX PRRC2C VCAN FOXG1

1.31e-05198685de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCellT_cells-GZMK+GZMB+_T_cells|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

PTTG1 BRIP1 KIF14 PRRG4 PLK4

1.31e-05198685085ba270f9defbf5ef45108c6d870e1d7c428479
ToppCell15-Airway-Mesenchymal-Mesenchyme_RSPO2+|Airway / Age, Tissue, Lineage and Cell class

PTTG1 CCDC18 KIF14 PLK4 PTTG2

1.34e-051996855c8b847b794b3e88722f5b841f2539a27251106c
ToppCellmild_COVID-19-T/NK_proliferative|World / disease group, cell group and cell class (v2)

PTTG1 BRIP1 SHMT1 KIF14 PLK4

1.34e-05199685d44cc74d7171d96add61dae821daf774b17d4c69
ToppCellCOVID-19-COVID-19_Mild-Myeloid-immature_Neutrophil|COVID-19_Mild / Disease, condition lineage and cell class

DNAH3 PADI4 BRIP1 KIF14 PTTG2

1.34e-05199685e222b90caf45904d8f763574e7b6aac13333df92
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-Proliferating-Cycling_Progenitors|6_mon / Sample Type, Dataset, Time_group, and Cell type.

PTTG1 BRIP1 CCDC18 KIF14 PLK4

1.34e-05199685a99516a5760f49a69b0fe45a9b2316e393252966
ToppCellBAL-Severe-cDC_10|Severe / Compartment, Disease Groups and Clusters

SYNPO2 LAD1 SYNPO PLCL1 CD200

1.34e-0519968554bdadd04abaf8caa948b0177c037bc089ca07e6
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|bone_marrow / Manually curated celltypes from each tissue

PTTG1 PADI4 VCAN KIF14 PRRG4

1.34e-05199685961666a677589c65f733f7262822689101d39ae3
ToppCellHealthy_donor-T/NK_proliferative|World / disease group, cell group and cell class (v2)

PTTG1 BRIP1 SHMT1 KIF14 PLK4

1.34e-051996851311dfd74b991f48b047a439f04f9bf7dfaa0e7a
ToppCellCOVID-19_Severe-T/NK_proliferative|COVID-19_Severe / disease group, cell group and cell class

PTTG1 BRIP1 SHMT1 KIF14 PLK4

1.34e-05199685af78837f3a7641a5bd98765eef9cb4f86034048c
ToppCellLPS_IL1RA-Endothelial-Endothelial-FOXM1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PTTG1 BRIP1 CCDC18 KIF14 PLK4

1.34e-05199685be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCellmild_COVID-19-T/NK_proliferative|mild_COVID-19 / disease group, cell group and cell class (v2)

PTTG1 BRIP1 SHMT1 KIF14 PLK4

1.34e-05199685df2fcaf01b1b48632f84e7355ef21d20853f0664
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells-Neuroepithelial_cell|2m / Sample Type, Dataset, Time_group, and Cell type.

PTTG1 BRIP1 CCDC18 KIF14 PLK4

1.37e-052006850d9b8d51a7630e70e60c76c763ff82df4c559152
ToppCellControl_saline-Endothelial-Endothelial-FOXM1|Control_saline / Treatment groups by lineage, cell group, cell type

PTTG1 BRIP1 CCDC18 KIF14 PLK4

1.37e-052006859bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-STK32A-|Neuronal / cells hierarchy compared to all cells using T-Statistic

TIAM1 SRGAP1 GRIK1 GRIK2 GRIK3

1.37e-052006856a44439e4a7ce3627271375b04cfcfb9467218f4
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells|2m / Sample Type, Dataset, Time_group, and Cell type.

PTTG1 BRIP1 CCDC18 KIF14 PLK4

1.37e-052006850675f580ccef705875854247bbfd4ee2bcf126a1
ToppCellBiopsy_Control_(H.)-Immune-Proliferating_Macrophages|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

PTTG1 BRIP1 CCDC18 KIF14 PLK4

1.37e-05200685ce9fad55f779afd3d6c5a9c5a15e2d9f548b7c7e
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-KLHDC8A-|Neuronal / cells hierarchy compared to all cells using T-Statistic

VCAN GRIK1 GRIK2 GRIK3 PDE11A

1.37e-052006851a04331862079092bc04b1010aa9228c0fa3d8c5
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-STK32A|Neuronal / cells hierarchy compared to all cells using T-Statistic

TIAM1 SRGAP1 GRIK1 GRIK2 GRIK3

1.37e-052006858d51b4f7b7002ee51401ebe5eaca1e8f04bfadd5
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-KLHDC8A|Neuronal / cells hierarchy compared to all cells using T-Statistic

VCAN GRIK1 GRIK2 GRIK3 PDE11A

1.37e-0520068505bcde6ce8f1354ef65e4eb9cbd963a92108081c
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-STK32A--L4-5|Neuronal / cells hierarchy compared to all cells using T-Statistic

TIAM1 SRGAP1 GRIK1 GRIK2 GRIK3

1.37e-05200685cb1f4b0d66da5b0466ff17b29e7034d451d93e4f
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-KLHDC8A--L5-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

VCAN GRIK1 GRIK2 GRIK3 PDE11A

1.37e-05200685fb56d430957e73fba17db7bc0127ecf3577e0867
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PADI4 VCAN LAD1 SHMT1

1.68e-051006843a7e5469de88745ac455c35deeb859d68dce73fa
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P2-Tnr|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PADI4 VCAN LAD1 SHMT1

1.68e-05100684187e31d4186b82a37569b98d83e4813017cc2ddd
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-7|TCGA-Brain / Sample_Type by Project: Shred V9

BRIP1 CCDC18 KIF14 PLK4

5.60e-05136684d94f0fbeb7b80d4cf0687d1924ebf8f9dd07358c
ToppCell3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-MAIT|GI_small-bowel / Manually curated celltypes from each tissue

ANKRD13C SLC19A3 FSBP PLK4

7.57e-051476844ba9a86ab7033688a9a2a2dc84c001a49af835b4
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_Inf._Macrophages|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PADI4 VCAN DNAH2 CCDC183

8.40e-0515168488f7498f29e43441e0982f9f97ea563edf2835a4
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DRD1 VCAN GRIK1 GRIK2

8.62e-051526848ff5a178a8f3550d89a003c0858820aab3773386
ToppCellInfluenza_Severe-CD4+_CTL|World / Disease group and Cell class

PTTG1 FSBP C3orf49 PDE11A

8.84e-051536840c6c2c6dbc81badd886f125f4e5ba0fb7d52101c
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FSIP2 VCAN GRIK2 CMYA5

9.30e-0515568477fdae85d36efb776db977eb424b32487ef222e4
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-6|TCGA-Kidney / Sample_Type by Project: Shred V9

PTTG1 KIF14 PLK4 FOXG1

9.53e-05156684d249747c7108a0edfc72d24c09b0b0e4ed662b40
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

VCAN GRIK1 GRIK2 PDE11A

9.77e-05157684516903469756c5fabfdf56d7bd59b3bdd7b44e39
ToppCellAdult-Mesenchymal-myofibroblast_cell-D175|Adult / Lineage, Cell type, age group and donor

FSIP2 NPR3 NALCN CD200

1.08e-04161684048b7dc00746987a24bf870d4d278c4183eb04a2
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

VCAN GRIK1 GRIK2 PDE11A

1.13e-041636848d17f44faf0549fe71a9a45f811f50d767275414
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SRGAP1 VCAN GRIK1 PDE11A

1.16e-0416468408819970174a3eb4eee8e1e675075828665b845e
ToppCell368C-Myeloid-Dendritic-cDC_activated|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

LAD1 DNAH2 PLCL1 CD200

1.16e-0416468467c636a2cc32e56c6186dc7e779cc19af04639d2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NYNRIN GRIK2 REN PLCL1

1.18e-04165684e2aebb2fe197151e019371b8960f76f0c2386f08
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NYNRIN GRIK2 REN PLCL1

1.18e-04165684b087771499aeb31cc4a338d2d0a9392a4ec1ac45
ToppCell368C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

LAD1 DNAH2 PLCL1 CD200

1.18e-041656849d2bdc42c13c8c2a68889bec8612a1ce56f659fa
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NYNRIN GRIK2 REN PLCL1

1.18e-04165684d8f8b088fd28a6b9dbd6b51bcaee42000e963321
ToppCellLV-16._Neuronal|World / Chamber and Cluster_Paper

PRRG4 GRIK2 GRIK3 RPGR

1.18e-041656846ed52cb756d21addf46c7f6c457458b01339fe04
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

VCAN LAD1 SHMT1 CNP

1.21e-04166684a7ac5a414e3e2ff01f1c452c0a85048b17cba0b6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 CCDC18 KIF14 PLK4

1.24e-0416768450c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCell10x5'-Lung-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|Lung / Manually curated celltypes from each tissue

PTTG1 VCAN KIF14 PLK4

1.24e-0416768482739226347d74897be000f429b73543a031af96
ToppCell343B-Myeloid-Dendritic-cDC_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PTTG1 BRIP1 PLCB1 SYNPO

1.24e-041676843461d14e36f09ddc6ee5549ca4797e16d3f37fcc
ToppCell10x5'-Lung-Hematopoietic_progenitors|Lung / Manually curated celltypes from each tissue

PTTG1 VCAN KIF14 PLK4

1.24e-04167684dec18caf0475002d4ad3c7bc7fc3050cbc8e6bae
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTTG1 BRIP1 KIF14 PLK4

1.24e-04167684bc132b51dec4e8f1cd2b2cd89f83641976e09292
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GABRP DIAPH2 GRIK2 CMYA5

1.27e-041686848072d0496b7b730c4601009eaa69ec5366d26d73
ToppCellCOVID-19-Heart-Neuronal|COVID-19 / Disease (COVID-19 only), tissue and cell type

PLCB1 GRIK2 GRIK3 RPGR

1.27e-0416868488c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTTG1 BRIP1 CCDC18 KIF14

1.30e-04169684b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTTG1 BRIP1 KIF14 PLK4

1.30e-04169684e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 CDHR3 DNAH2 DNAI4

1.30e-0416968414aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell356C-Myeloid-Dendritic-cDC_activated|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

LAD1 SYNPO PLCL1 CD200

1.30e-0416968444d201361eb497222a4972a0e10bac1e05dcfd0a
ToppCell356C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

LAD1 SYNPO PLCL1 CD200

1.33e-04170684513d9036aa41d4d902da8baa66a66206abb6f3b0
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_mature_DC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SYNPO2 LAD1 ARHGAP21 CD200

1.36e-04171684341f9f79c1ed654ab347e25dc4936f89ffdf9617
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 IL16 NALCN VCAN

1.36e-041716845d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPR3 SRGAP1 SYNPO GRIK2

1.39e-04172684073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRIP1 CCDC18 KIF14 FSBP

1.39e-0417268435c20de4db47dbf31c857d23c7a25cd7f95c085c
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 CDHR3 DNAH2 DNAI4

1.42e-04173684c3762655caa79ac4879876f470d32578a3c93b01
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 CCDC18 KIF14 PLK4

1.45e-0417468484da9faff088d05233183b425385beb054c92d1b
DrugCrotamiton [483-63-6]; Down 200; 19.6uM; MCF7; HT_HG-U133A

KLHL24 GTF2I PLCB1 PRKAR2A PRRG4 PLK4 AHNAK2

9.65e-071796773388_DN
Drug0316684-0000 [391209-55-5]; Down 200; 10uM; MCF7; HT_HG-U133A

BRIP1 GTF2I TIAM1 ATRX RRP12 SRPRA PRRG4

1.60e-061936777052_DN
DrugNiflumic acid [4394-00-7]; Up 200; 14.2uM; PC3; HT_HG-U133A

GABRP ALLC PADI4 DRD1 PLCB1 GRIK1 PDE11A

1.96e-061996775071_UP
DrugLY339434

GRIK1 GRIK2 GRIK3

2.02e-069673CID006324635
Drugmilrinone

NPR3 PLCB1 PRKAR2A REN CNP PDE11A

5.30e-06150676CID000004197
Drugcaffeine

DRD1 CYP3A43 PLCB1 PRKAR2A GRIK1 GRIK2 GRIK3 REN CNP PDE11A

5.43e-065626710CID000002519
Drugspegazzinine

GABRP FOXG1

8.53e-062672CID003083986
Drug5-nitro-6,7,8,9-tetrahydrobenzo(G)indole-2,3-dione-3-oxime

GRIK1 GRIK2

8.53e-062672ctd:C084273
Drugdecahydroisoquinoline

GRIK1 GRIK2 GRIK3

1.33e-0516673CID000097812
Druggenistein; Up 200; 10uM; HL60; HT_HG-U133A

PADI4 BRIP1 ATRX ABHD3 MOB1A SRPRA

1.46e-051796761176_UP
DrugHomochlorcyclizine dihydrochloride [1982-36-1]; Up 200; 10.4uM; PC3; HT_HG-U133A

KLHL24 GTF2I TIAM1 RRP12 PRKAR2A GRIK2

1.70e-051846767295_UP
DrugEN-1530

GABRP NPR3 DRD1 GRIK1 GRIK2 GRIK3 REN

1.75e-05278677CID000004425
DrugEthotoin [86-35-1]; Down 200; 19.6uM; PC3; HT_HG-U133A

KLHL24 GTF2I ATRX SHMT1 SRPRA PRRG4

1.92e-051886764545_DN
DrugPrimaquine diphosphate [63-45-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A

PDS5B KLHL24 PRRC2C DIAPH2 ANKRD11 PRKAR2A

1.92e-051886764845_DN
Drug2-propylpentanoic acid; Down 200; 200uM; HL60; HT_HG-U133A

GTF2I VCAN RRP12 SRPRA PRRG4 PLK4

2.10e-051916766173_DN
DrugDizocilpine maleate [77086-22-7]; Down 200; 11.8uM; MCF7; HT_HG-U133A

BRIP1 GTF2I MOB1A SHMT1 SRPRA PLK4

2.16e-051926766223_DN
DrugLY382884

GRIK1 GRIK2 GRIK3

2.28e-0519673CID000656723
DrugDantrolene sodium salt [14663-23-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A

GTF2I ATRX MOB1A PLCB1 PRKAR2A SRPRA

2.30e-051946763867_DN
DrugCiprofloxacin hydrochloride [93107-08-5]; Up 200; 10.8uM; MCF7; HT_HG-U133A

PDS5B DNAH3 DRD1 RRP12 PLCB1 RPGR

2.36e-051956765299_UP
Drug(+/-)-blebbistatin; Up 200; 17uM; MCF7; HT_HG-U133A_EA

KLHL24 DRD1 ATRX ABHD3 RPGR PLK4

2.43e-05196676837_UP
DrugGabexate mesilate [56974-61-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A

GTF2I RRP12 LAD1 SHMT1 SRPRA RPGR

2.43e-051966767357_DN
DrugNaproxen [22204-53-1]; Down 200; 17.4uM; PC3; HT_HG-U133A

KLHL24 BRIP1 PRRC2C SHMT1 SYNPO RPGR

2.50e-051976761828_DN
DrugMinoxidil [38304-91-5]; Down 200; 19.2uM; PC3; HT_HG-U133A

PDS5B NPR3 GTF2I VCAN PLCB1 SHMT1

2.50e-051976764216_DN
Drug(cis-) Nanophine [5072-45-7]; Down 200; 26.8uM; MCF7; HT_HG-U133A

DRD1 GTF2I MOB1A PLCB1 SRPRA PLK4

2.50e-051976763889_DN
DrugLobelanidine hydrochloride [6112-86-3]; Up 200; 10.6uM; MCF7; HT_HG-U133A

NPR3 DRD1 VCAN RRP12 SYNPO FOXG1

2.57e-051986765500_UP
DrugAltretamine [654-05-6]; Up 200; 19uM; MCF7; HT_HG-U133A

VCAN PLCB1 MYH15 SYNPO FOXG1 PDE11A

2.65e-051996765688_UP
Drug5162773; Up 200; 7uM; MCF7; HT_HG-U133A_EA

PDS5B GTF2I ATRX SRPRA PLK4 PDE11A

2.65e-05199676892_UP
DrugNS 102

GRIK1 GRIK2 GRIK3

3.60e-0522673CID005282252
Drugaminothiazole 6

GRIK1 GRIK3

5.10e-054672CID005329388
Drugacromelic acid B

GRIK1 GRIK3

5.10e-054672CID000158974
DrugBrn 1074551

GRIK1 GRIK3

5.10e-054672CID000120220
Drugpotassium tetrathionate

GRIK1 REN

5.10e-054672CID000061701
DrugdiCl-HQC

GRIK1 GRIK3

5.10e-054672CID003018579
Drugfelbamate

GABRP GRIK1 GRIK2 GRIK3

5.43e-0570674CID000003331
Drugguanine

GABRP USP14 PTTG1 NPR3 DRD1 BRIP1 TIAM1 PLCB1 SHMT1 PRKAR2A GRIK1

5.99e-059026711CID000000764
Drugzaprinast

NPR3 PRKAR2A GRIK1 REN PDE11A

6.02e-05141675CID000005722
DrugAC1L1DME

VCAN GRIK1 GRIK2 GRIK3

7.11e-0575674CID000002414
Drugipenoxazone

GRIK1 GRIK3

8.48e-055672CID000065882
DrugpBB-PzDA

GRIK1 GRIK3

8.48e-055672CID000124528
Drugtibalosine

GRIK1 REN

8.48e-055672CID000068828
Drugbromowillardiine

GRIK1 GRIK3

8.48e-055672CID000167842
Drug3-hydroxy-2-quinoxalinecarboxylic acid

GRIK1 GRIK3

8.48e-055672CID000071001
DrugLY293558

GRIK1 GRIK2 GRIK3

9.34e-0530673CID000127894
Drugrolipram

NPR3 PRKAR2A GRIK1 SYNPO GRIK2 GRIK3

1.00e-04253676CID000005092
Drug4-methylglutamic acid

GRIK1 GRIK2 GRIK3

1.03e-0431673CID000005365
DrugD-N-Q

GABRP GRIK1 GRIK2 GRIK3

1.11e-0484674CID000003140
Drugwillardine

GRIK1 GRIK2 GRIK3

1.14e-0432673CID000005123
Drugketamine

GABRP PRRG4 GRIK1 GRIK2 GRIK3 REN

1.22e-04262676CID000003821
Drug3-acetylisoquinoline

GRIK1 GRIK3

1.27e-046672CID000124656
Drugpropylbutyldopamine

DRD1 REN

1.27e-046672CID000156067
Drugethylamine hydrochloride

DRD1 GRIK1

1.27e-046672CID000011198
Drughaloperidol

GABRP DRD1 GRIK1 GRIK2 GRIK3 REN FOXG1

1.57e-04394677CID000003559
Drugpapaverine

NPR3 PLCB1 REN CNP PDE11A

1.71e-04176675CID000004680
Drugfluorocyclobutane

GRIK1 GRIK3

1.77e-047672CID011051569
DrugH-8105

GABRP NPR3 DRD1 PLCB1 GRIK1 REN

1.81e-04282676CID000164531
DrugL-quisqualic acid

GABRP PLCB1 GRIK1 GRIK2 GRIK3

1.90e-04180675CID000001209
DrugL-BMAA

GRIK1 GRIK2 GRIK3

1.91e-0438673CID000028558
Drug7-OH-DPAT

DRD1 GRIK1 GRIK3

2.06e-0439673CID000001219
DrugDETC-MeSO

GRIK1 GRIK2 GRIK3

2.06e-0439673CID003035711
DrugEthylnitrosourea

PTTG1 NPR3 DRD1 ATRX ANKRD11 GRIK1

2.15e-04291676ctd:D005038
DrugRapamycin; Up 200; 0.1uM; PC3; HT_HG-U133A

DNAH3 KLHL24 VCAN GRIK2 REN

2.27e-041876751242_UP
Drug2-bromoethylamine

NPR3 REN

2.36e-048672ctd:C004504
DrugAC1L1B65

GRIK1 GRIK3

2.36e-048672CID000001300
Drugperzinfotel

GRIK1 GRIK3

2.36e-048672CID006918236
DrugNocodazole [31430-18-9]; Down 200; 13.2uM; MCF7; HT_HG-U133A

BRIP1 GTF2I ABHD3 SRPRA PLK4

2.38e-041896756793_DN
DrugChlorpromazine hydrochloride [69-09-0]; Up 200; 11.2uM; MCF7; HT_HG-U133A

GTF2I PLCB1 SRPRA RPGR PLK4

2.38e-041896751700_UP
Drugcyclothiazide

GABRP GRIK1 GRIK2 GRIK3

2.43e-04103674CID000002910
DrugAmpyrone [83-07-8]; Down 200; 19.6uM; PC3; HT_HG-U133A

KLHL24 ATRX PRRC2C MOB1A PRKAR2A

2.44e-041906754507_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A

GTF2I RRP12 LAD1 SRPRA PLK4

2.44e-041906752137_DN
DrugLatex

PTTG1 NPR3 BRIP1 KIF14 PLK4

2.50e-04191675ctd:D007840
Drugradicicol, diheterospora chlamydosporia; Up 200; 0.1uM; MCF7; HT_HG-U133A

NPR3 DRD1 RRP12 ABHD3 PLCB1

2.56e-041926755216_UP
Drugtetradotoxin

GABRP NPR3 DRD1 GRIK1 GRIK2 GRIK3 REN

2.60e-04428677CID000020382
DrugKetanserin tartrate hydrate [83846-83-7]; Down 200; 7uM; MCF7; HT_HG-U133A

BRIP1 ATRX DIAPH2 PRKAR2A SRPRA

2.62e-041936753209_DN
DrugClobetasol propionate [25122-46-7]; Down 200; 8.6uM; MCF7; HT_HG-U133A

BRIP1 GTF2I ATRX PLCB1 SRPRA

2.62e-041936756835_DN
DrugEucatropine hydrochloride [536-93-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A

GTF2I ATRX MOB1A PLCB1 SRPRA

2.62e-041936753841_DN
DrugRp-cAMPS

NPR3 DRD1 PRKAR2A GRIK1 GRIK3

2.68e-04194675CID006426631
DrugH-7 dihydrochloride; Up 200; 100uM; MCF7; HT_HG-U133A

IL16 LAD1 PRKAR2A SYNPO BAP1

2.68e-041946755936_UP
DrugDomperidone maleate; Down 200; 7.4uM; MCF7; HT_HG-U133A

KLHL24 BRIP1 GTF2I SHMT1 SRPRA

2.68e-041946752655_DN
DrugSB 202190; Down 200; 1uM; PC3; HT_HG-U133A

ATRX NYNRIN VCAN MOB1A SRPRA

2.75e-041956757058_DN
DrugN6-methyladenosine [1867-73-8]; Up 200; 14.2uM; MCF7; HT_HG-U133A

RRP12 DIAPH2 PLCB1 PRRG4 GRIK1

2.75e-041956752626_UP
DrugAmethopterin (R,S) [59-05-2]; Down 200; 8.8uM; PC3; HT_HG-U133A

TIAM1 VCAN RRP12 SRPRA SYNPO

2.75e-041956756654_DN
Drugwortmannin from Penicillium funiculosum; Up 200; 0.01uM; HL60; HT_HG-U133A

KLHL24 ATRX PLCB1 PRKAR2A PLK4

2.75e-041956751184_UP
DrugMevalonic-D, L acid lactone [674-26-0]; Down 200; 30.8uM; MCF7; HT_HG-U133A

KLHL24 PLCB1 PRKAR2A RPGR BAP1

2.75e-041956753459_DN
DrugCisapride [81098-60-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A

KLHL24 RRP12 PRKAR2A PRRG4 RPGR

2.75e-041956755305_UP
DrugMetrizamide [31112-62-6]; Up 200; 5uM; HL60; HT_HG-U133A

KLHL24 GTF2I RRP12 PLCB1 PLK4

2.75e-041956751318_UP
DrugCimetidine [51481-61-9]; Up 200; 15.8uM; PC3; HT_HG-U133A

PADI4 RRP12 PLCB1 REN PLK4

2.75e-041956754063_UP
Drugikarugamycin; Up 200; 2uM; MCF7; HT_HG-U133A_EA

KLHL24 PLCB1 PRKAR2A PLK4 TRIM44

2.75e-04195675866_UP
DrugMethoxy-8-psoralen [298-81-7]; Down 200; 18.6uM; PC3; HT_HG-U133A

TIAM1 NYNRIN SYNPO GRIK2 PLK4

2.75e-041956756661_DN
DrugJoro spider toxin

GRIK1 GRIK2 GRIK3

2.76e-0443673CID000119582
DrugRanitidine hydrochloride [66357-59-3]; Down 200; 11.4uM; MCF7; HT_HG-U133A

DNAH3 KLHL24 BRIP1 RRP12 PLCB1

2.81e-041966755425_DN
DrugPirenzepine dihydrochloride [29868-97-1]; Down 200; 9.4uM; MCF7; HT_HG-U133A

DNAH3 KLHL24 TIAM1 DIAPH2 FOXG1

2.81e-041966757226_DN
Drugfluphenazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A

PDS5B USP14 DNAH3 BRIP1 SRPRA

2.81e-041966756954_DN
DrugDequalinium dichloride [522-51-0]; Up 200; 7.6uM; HL60; HT_HG-U133A

PTTG1 GTF2I VCAN PRKAR2A KIF14

2.81e-041966751276_UP
DrugHydroflumethiazide [135-09-1]; Up 200; 12uM; MCF7; HT_HG-U133A

KLHL24 ATRX RPGR BAP1 AHNAK2

2.81e-041966751687_UP
DrugClemizole hydrochloride [1163-36-6]; Up 200; 11uM; MCF7; HT_HG-U133A

GABRP DIAPH2 PRKAR2A MYH15 CD200

2.81e-041966752301_UP
Drugaspirin, USP; Down 200; 100uM; MCF7; HT_HG-U133A

PDS5B DNAH3 KLHL24 LAD1 BAP1

2.81e-041966756924_DN
DrugCyclosporin A [59865-13-3]; Down 200; 3.4uM; PC3; HT_HG-U133A

DNAH3 KLHL24 TIAM1 RRP12 MYH15

2.81e-041966754586_DN
DrugAG-013608 [351320-38-2]; Up 200; 10uM; MCF7; HT_HG-U133A

KLHL24 NPR3 BRIP1 VCAN CD200

2.81e-041966756435_UP
DrugMetformin hydrochloride [1115-70-4]; Up 200; 24.2uM; HL60; HT_HG-U133A

BRIP1 GTF2I VCAN MOB1A PLK4

2.88e-041976751858_UP
Drugstaurosporine; Up 200; 0.01uM; SKMEL5; HG-U133A

DNAH3 IL16 CYP3A43 LAD1 PLCB1

2.88e-04197675508_UP
Diseasecortisol secretion measurement

ALLC SLC19A3

9.96e-057652EFO_0004642
Diseasechronic fatigue syndrome (is_marker_for)

IL16 REN

2.13e-0410652DOID:8544 (is_marker_for)
DiseaseNeuroendocrine Tumors

ATRX BAP1

2.59e-0411652C0206754
DiseaseUnipolar Depression

PLCB1 REN CMYA5 CNP PDE11A

2.69e-04259655C0041696
DiseaseSjogren's Syndrome

PTTG1 GTF2I

3.67e-0413652C1527336
DiseaseSicca Syndrome

PTTG1 GTF2I

3.67e-0413652C0086981
Diseaseunipolar depression, bipolar disorder

MYH15 GRIK2 GRIK3 PLCL1

3.96e-04156654EFO_0003761, MONDO_0004985
Diseaseurate measurement, bone density

FSIP2 GABRP USP14 ANKRD11 PLCB1 PRKAR2A KIF14

4.20e-04619657EFO_0003923, EFO_0004531
DiseaseMicrocephaly

KIF14 PLK4 FOXG1

4.42e-0467653C0025958
DiseaseMYELODYSPLASTIC SYNDROME

BRIP1 ATRX PLCB1

4.42e-0467653C3463824
Diseaseforehead morphology measurement

BRIP1 GRIK1

4.93e-0415652EFO_0007844
Diseaseserum alanine aminotransferase measurement

PDS5B DRD1 BRIP1 NYNRIN DNAH2 SHMT1 GRIK3 CMYA5

6.27e-04869658EFO_0004735
DiseaseSchizophrenia

DRD1 PLCB1 SHMT1 GRIK1 GRIK2 GRIK3 CMYA5 CNP

6.96e-04883658C0036341
Diseaserefractive error, age at onset, Myopia

DRD1 BRIP1 GRIK1 PDE11A

8.80e-04193654EFO_0004847, HP_0000545, MONDO_0004892
Diseaselung cancer

BRIP1 GRIK1

9.77e-0421652MONDO_0008903
Diseasemalignant astrocytoma (is_marker_for)

IL16 ATRX

1.17e-0323652DOID:3069 (is_marker_for)
DiseaseVisual seizure

DRD1 GRIK1 FOXG1

1.46e-03101653C0270824
DiseaseEpileptic drop attack

DRD1 GRIK1 FOXG1

1.46e-03101653C0270846
DiseaseGeneralized seizures

DRD1 GRIK1 FOXG1

1.46e-03101653C0234533
DiseaseClonic Seizures

DRD1 GRIK1 FOXG1

1.46e-03101653C0234535
DiseaseVertiginous seizure

DRD1 GRIK1 FOXG1

1.46e-03101653C0422855
DiseaseGustatory seizure

DRD1 GRIK1 FOXG1

1.46e-03101653C0422854
DiseaseSeizures, Somatosensory

DRD1 GRIK1 FOXG1

1.46e-03101653C0422850
DiseaseOlfactory seizure

DRD1 GRIK1 FOXG1

1.46e-03101653C0422853
DiseaseSeizures, Auditory

DRD1 GRIK1 FOXG1

1.46e-03101653C0422852
DiseaseGeneralized Absence Seizures

DRD1 GRIK1 FOXG1

1.46e-03101653C4505436
DiseaseConvulsive Seizures

DRD1 GRIK1 FOXG1

1.46e-03101653C0751494
DiseaseSeizures, Sensory

DRD1 GRIK1 FOXG1

1.46e-03101653C0751496
DiseaseJacksonian Seizure

DRD1 GRIK1 FOXG1

1.46e-03101653C0022333
DiseaseNon-epileptic convulsion

DRD1 GRIK1 FOXG1

1.46e-03101653C0751056
DiseaseAtonic Absence Seizures

DRD1 GRIK1 FOXG1

1.46e-03101653C0751123
DiseaseComplex partial seizures

DRD1 GRIK1 FOXG1

1.46e-03101653C0149958
DiseaseSingle Seizure

DRD1 GRIK1 FOXG1

1.46e-03101653C0751110
DiseaseEpileptic Seizures

DRD1 GRIK1 FOXG1

1.46e-03101653C4317109
DiseaseNonepileptic Seizures

DRD1 GRIK1 FOXG1

1.46e-03101653C3495874
DiseaseTonic Seizures

DRD1 GRIK1 FOXG1

1.50e-03102653C0270844
DiseaseAbsence Seizures

DRD1 GRIK1 FOXG1

1.50e-03102653C4316903
DiseaseConvulsions

DRD1 GRIK1 FOXG1

1.50e-03102653C4048158
DiseaseHypermetropia

ANKRD11 KIF14 ARHGAP21

1.54e-03103653HP_0000540
DiseaseSeizures, Focal

DRD1 GRIK1 FOXG1

1.59e-03104653C0751495
DiseaseMyoclonic Seizures

DRD1 GRIK1 FOXG1

1.59e-03104653C4317123
DiseaseTonic - clonic seizures

DRD1 GRIK1 FOXG1

1.59e-03104653C0494475
Diseasegamma-glutamyltyrosine measurement

BRIP1 ARHGAP21

1.62e-0327652EFO_0021144
DiseaseHematopoetic Myelodysplasia

ATRX PLCB1

1.87e-0329652C2713368
DiseaseMajor Depressive Disorder

PLCB1 CMYA5 CNP PDE11A

2.05e-03243654C1269683
DiseaseSevere Congenital Microcephaly

PLK4 FOXG1

2.13e-0331652C3853041

Protein segments in the cluster

PeptideGeneStartEntry
KSNSFISIPKMEVKS

ANKRD11

376

Q6UB99
VEMTKSFDFPTLITK

VCAN

741

P13611
REKPMLKFSVSFKAN

ALLC

376

Q8N6M5
RDGSTMTFFKKSKIS

GRIK1

701

P39086
KQTIEFKKMFKSTSD

FAM220BP

216

B1ANY3
KKTFKATIAMSQEFP

ANKRD13C

446

Q8N6S4
MKAKSIREFDKRFTS

ABHD3

296

Q8WU67
TLSRMKDFTKGFSPE

BAP1

111

Q92560
PESSFKMSFKRETKV

DRD1

256

P21728
DKFVEKMTSFTKTAR

DIAPH2

941

O60879
RTVKPEFEKFSMEVK

NPR3

326

P17342
PKTDASVKAIFSKVM

PDS5B

516

Q9NTI5
SLMTLSTKTPKDFFT

PADI4

181

Q9UM07
MADKKYKETFSAPSR

KIF14

191

Q15058
FRMKPKKENSETTLT

LAD1

376

O00515
PSFASIIEKMAKSTK

FSIP2

1521

Q5CZC0
DRKEVKMIPKSSFSI

FOXG1

6

P55316
ETSFNKKEKSEMVPS

NUP85

36

Q9BW27
VKFTKSFELMSPKCS

PDE11A

436

Q9HCR9
FFMKESSTASSREKP

IL16

101

Q14005
KKKAVSPENMVTFSE

CD200

66

P41217
SSPPRFKTEKMESKT

BRIP1

1031

Q9BX63
FKTEKMESKTVLPFT

BRIP1

1036

Q9BX63
FKGPEFRSRSKMKTE

ATRX

141

P46100
ATKRKVFEMDPKSLT

KLHL24

21

Q6TFL4
EFSSPKLFTAKMRKL

C3orf49

131

Q96BT1
TLLSPAFTSVKFKEM

CYP3A43

131

Q9HB55
NRSSSEPMRKKTKFS

DNAH3

151

Q8TD57
TSIFSPMKKEVKTSL

DNAH3

181

Q8TD57
STDFQKKPRDKMFSS

CCDC18

91

Q5T9S5
QKFTFSIMVPERTAK

CDHR3

346

Q6ZTQ4
SKSFMTTKPADVKET

CMYA5

1866

Q8N3K9
PSSISFKSVEKKMTD

CCDC183

366

Q5T5S1
IFFRKMSSSGAKDKP

CNP

16

P09543
TQPKKSISFFATMKA

DNAI4

61

Q5VTH9
AKKRKMFESFIESVP

PRKAR2A

246

P13861
EDGATMTFFKKSKIS

GRIK2

686

Q13002
ATMTFFKKSKISTFE

GRIK3

691

Q13003
KKPEMFETAIKESTS

GTF2I

806

P78347
STMKASRFVKAFEKD

DNAH2

1411

Q9P225
SMFFHAKPSREIKKS

SLC19A3

196

Q9BZV2
SDLTMKTSDKFKFVF

GABRP

381

O00591
TPMINKTGFKFSAEK

LRRC8D

251

Q7L1W4
PSFSAKKMTEKTVKA

PTTG1

86

O95997
MKAFAKSGTPLSFKV

NYNRIN

1881

Q9P2P1
DKKKISATSIFFESM

SHMT1

156

P34896
REKSTKKMSPFFGNL

RPGR

661

Q92834
LKFKSSDPKVTRDQM

TRIM44

241

Q96DX7
MSTPSRFKKDKEIIA

SRGAP1

1

Q7Z6B7
RKSMFTFVEKPKVTP

SYNPO

621

Q8N3V7
MSFLFSSRSSKTFKP

MOB1A

1

Q9H8S9
MFPKATDLTFKTKLF

MYH15

551

Q9Y2K3
TDTTTFKRIFLKRMP

REN

26

P00797
PTTFSLTFKMESARK

PRRC2C

2241

Q9Y520
PSFSAKKMTEKTVKA

PTTG3P

86

Q9NZH4
PSFSAKKMTEKTVKT

PTTG2

86

Q9NZH5
MKRSFSEFPSRKDSK

SKIV2L

766

Q15477
KMTVFPKNKSSTDFS

PLK4

321

O00444
PVLIKKFSDTSKAFM

RRP12

181

Q5JTH9
VTTKDSRFKIPKFKM

AHNAK2

2476

Q8IVF2
KKTVSFSSMPSEKKI

PLCL1

91

Q15111
EAKRRSTTKPMFTFK

SYNPO2

686

Q9UMS6
STTKPMFTFKEPKVS

SYNPO2

691

Q9UMS6
GPTFMETASFKKKRS

TIAM1

156

Q13009
KFLKEVKSATPMNTR

TIGD1

56

Q96MW7
SDFKSNISEPTKKVM

FSBP

91

O95073
ESSKIRAPTTMKKFE

SRPRA

126

P08240
RAPTTMKKFEDSEKA

SRPRA

131

P08240
TKGFRVFKKSMSLPS

PRRG4

211

Q9BZD6
EISKKRNKSFEMSSF

PLCB1

556

Q9NQ66
PELQEKMVSFRSKFK

USP14

361

P54578
MRKTFEKKPTATGTF

ARHGAP21

1131

Q5T5U3
SDFTVPKIRESFMKQ

NALCN

651

Q8IZF0