Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionallyl-alcohol dehydrogenase activity

AKR1B10 AKR1B1

5.31e-054602GO:0047655
GeneOntologyMolecularFunctiondATP binding

ST13P5 ST13

8.83e-055602GO:0032564
GeneOntologyMolecularFunctionadenyl deoxyribonucleotide binding

ST13P5 ST13

1.32e-046602GO:0032558
GeneOntologyMolecularFunctionpurine deoxyribonucleotide binding

ST13P5 ST13

1.85e-047602GO:0032554
GeneOntologyMolecularFunctiondeoxyribonucleotide binding

ST13P5 ST13

3.15e-049602GO:0032552
GeneOntologyMolecularFunctioncytoskeletal protein binding

MYH1 KIFBP CENPF PPP1R9A SYNE2 CGN MYO18A TMOD1 DMD CCDC181 TNNT1

3.81e-0410996011GO:0008092
GeneOntologyMolecularFunctionactin binding

MYH1 PPP1R9A SYNE2 CGN MYO18A TMOD1 DMD

5.63e-04479607GO:0003779
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

CECR2 MYO18A CHD2 RAD50

5.78e-04127604GO:0008094
GeneOntologyMolecularFunctionG-quadruplex DNA binding

XRN1 RAD50

7.89e-0414602GO:0051880
GeneOntologyMolecularFunctionretinal dehydrogenase activity

AKR1B10 AKR1B1

7.89e-0414602GO:0001758
GeneOntologyMolecularFunctionaldose reductase (NADPH) activity

AKR1B10 AKR1B1

7.89e-0414602GO:0004032
GeneOntologyMolecularFunctionHsp70 protein binding

ST13P5 ST13 IQCG

9.01e-0463603GO:0030544
GeneOntologyMolecularFunctiontropomyosin binding

TMOD1 TNNT1

9.09e-0415602GO:0005523
GeneOntologyMolecularFunctionall-trans-retinol dehydrogenase (NADP+) activity

AKR1B10 AKR1B1

9.09e-0415602GO:0052650
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

CECR2 MYO18A CHD2 NIPBL RAD50

1.14e-03262605GO:0140097
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

SEPTIN8 SEPTIN3 SEPTIN14 MYO18A CCT6B CHD2 DYNC1H1 RAD50

2.13e-03775608GO:0017111
GeneOntologyMolecularFunctionATP-dependent activity

MYH1 CECR2 MYO18A CCT6B CHD2 DYNC1H1 RAD50

2.36e-03614607GO:0140657
GeneOntologyMolecularFunctionalcohol dehydrogenase (NADP+) activity

AKR1B10 AKR1B1

2.97e-0327602GO:0008106
GeneOntologyMolecularFunctiondynein complex binding

CFAP100 CENPF

3.19e-0328602GO:0070840
GeneOntologyMolecularFunctiondynein light intermediate chain binding

RILPL1 DYNC1H1

3.19e-0328602GO:0051959
GeneOntologyMolecularFunctionpyrophosphatase activity

SEPTIN8 SEPTIN3 SEPTIN14 MYO18A CCT6B CHD2 DYNC1H1 RAD50

3.47e-03839608GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

SEPTIN8 SEPTIN3 SEPTIN14 MYO18A CCT6B CHD2 DYNC1H1 RAD50

3.50e-03840608GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

SEPTIN8 SEPTIN3 SEPTIN14 MYO18A CCT6B CHD2 DYNC1H1 RAD50

3.50e-03840608GO:0016818
GeneOntologyMolecularFunctionaldo-keto reductase (NADPH) activity

AKR1B10 AKR1B1

4.16e-0332602GO:0004033
GeneOntologyMolecularFunctionprotein domain specific binding

USP8 CTR9 PPP1R9A ZBTB21 DMD ST13P5 NIPBL ST13

4.48e-03875608GO:0019904
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYH1 MYO18A DYNC1H1

5.39e-03118603GO:0003774
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

CECR2 CHD2

5.53e-0337602GO:0140658
GeneOntologyMolecularFunctionRNA polymerase II complex binding

RTF1 CTR9

6.13e-0339602GO:0000993
GeneOntologyMolecularFunctionunfolded protein binding

CCT6B ST13P5 ST13

6.46e-03126603GO:0051082
GeneOntologyBiologicalProcesscytoskeleton-dependent cytokinesis

SEPTIN8 USP8 SEPTIN3 CECR2 SEPTIN14 CHMP3

1.67e-06127596GO:0061640
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

CFAP100 CCDC13 KIFBP SYNE2 CGN CHMP3 MAP7D2 CEP126 DYNC1H1 CCDC40 IQCG

5.28e-067205911GO:0000226
GeneOntologyBiologicalProcessorganelle assembly

CFAP100 CCDC13 CENPF SYNE2 CHMP3 TMOD1 RILPL1 CEP126 RB1CC1 TNNT1 DYNC1H1 CCDC40 IQCG

1.54e-0511385913GO:0070925
GeneOntologyBiologicalProcesscytokinesis

SEPTIN8 USP8 SEPTIN3 CECR2 SEPTIN14 CHMP3

2.53e-05204596GO:0000910
GeneOntologyBiologicalProcessnegative regulation of protein refolding

ST13P5 ST13

8.00e-055592GO:0061084
GeneOntologyBiologicalProcessregulation of protein refolding

ST13P5 ST13

1.20e-046592GO:0061083
GeneOntologyBiologicalProcesscell division

SEPTIN8 USP8 SEPTIN3 CENPF CECR2 SEPTIN14 SYCP1 CHMP3 DYNC1H1

1.51e-04697599GO:0051301
GeneOntologyBiologicalProcessnegative regulation of protein folding

ST13P5 ST13

1.67e-047592GO:1903333
GeneOntologyBiologicalProcesscell cycle process

SEPTIN8 USP8 SEPTIN3 CENPF CECR2 SEPTIN14 SYCP1 CHMP3 CEP126 NIPBL DYNC1H1 KCNH5 RAD50

1.75e-0414415913GO:0022402
GeneOntologyBiologicalProcessmicrotubule-based process

CFAP100 CCDC13 KIFBP SYNE2 CGN CHMP3 MAP7D2 CEP126 DYNC1H1 CCDC40 IQCG

1.78e-0410585911GO:0007017
GeneOntologyBiologicalProcesscilium assembly

CFAP100 CCDC13 SYNE2 RILPL1 CEP126 CCDC40 IQCG

2.65e-04444597GO:0060271
GeneOntologyBiologicalProcessnucleus localization

SYNE2 DMD DYNC1H1

2.71e-0444593GO:0051647
GeneOntologyBiologicalProcessdaunorubicin metabolic process

AKR1B10 AKR1B1

2.86e-049592GO:0044597
GeneOntologyBiologicalProcessdoxorubicin metabolic process

AKR1B10 AKR1B1

3.57e-0410592GO:0044598
GeneOntologyBiologicalProcesspolyketide metabolic process

AKR1B10 AKR1B1

3.57e-0410592GO:0030638
GeneOntologyBiologicalProcessaminoglycoside antibiotic metabolic process

AKR1B10 AKR1B1

3.57e-0410592GO:0030647
GeneOntologyBiologicalProcesscilium organization

CFAP100 CCDC13 SYNE2 RILPL1 CEP126 CCDC40 IQCG

4.04e-04476597GO:0044782
GeneOntologyCellularComponentseptin complex

SEPTIN8 SEPTIN3 SEPTIN14

8.00e-0614603GO:0031105
GeneOntologyCellularComponentseptin ring

SEPTIN8 SEPTIN3 SEPTIN14

8.00e-0614603GO:0005940
GeneOntologyCellularComponentcell cortex

SEPTIN8 SEPTIN3 SEPTIN14 PPP1R9A TMOD1 RAI14 DYNC1H1 SPINK5

1.04e-05371608GO:0005938
GeneOntologyCellularComponentseptin cytoskeleton

SEPTIN8 SEPTIN3 SEPTIN14

1.23e-0516603GO:0032156
GeneOntologyCellularComponentmanchette

CCDC181 DYNC1H1 IQCG

7.00e-0528603GO:0002177
GeneOntologyCellularComponentCdc73/Paf1 complex

RTF1 CTR9

1.69e-047602GO:0016593
GeneOntologyCellularComponentactin cytoskeleton

MYH1 PPP1R9A CGN MYO18A TMOD1 RAI14 TNNT1 IQCG

2.29e-04576608GO:0015629
GeneOntologyCellularComponentcondensed chromosome

CENPF KMT5B RASSF2 SYCP1 CHMP3 RAD50

2.46e-04307606GO:0000793
GeneOntologyCellularComponentfilopodium

PPP1R9A SYNE2 DMD DYNC1H1

4.31e-04123604GO:0030175
GeneOntologyCellularComponentmyosin complex

MYH1 CGN MYO18A

6.52e-0459603GO:0016459
GeneOntologyCellularComponentsarcomere

MYH1 SYNE2 TMOD1 DMD TNNT1

7.38e-04249605GO:0030017
GeneOntologyCellularComponentmyofibril

MYH1 SYNE2 TMOD1 DMD TNNT1

1.11e-03273605GO:0030016
GeneOntologyCellularComponentchromosome, centromeric region

CENPF KMT5B RASSF2 SYCP1 CHMP3

1.17e-03276605GO:0000775
GeneOntologyCellularComponentactin-based cell projection

PPP1R9A SYNE2 DMD AKR1B1 DYNC1H1

1.21e-03278605GO:0098858
GeneOntologyCellularComponentchromosomal region

CENPF KMT5B RASSF2 SYCP1 CHMP3 RAD50

1.29e-03421606GO:0098687
GeneOntologyCellularComponentcontractile muscle fiber

MYH1 SYNE2 TMOD1 DMD TNNT1

1.45e-03290605GO:0043292
GeneOntologyCellularComponentcell division site

SEPTIN8 SEPTIN3 SEPTIN14

1.58e-0380603GO:0032153
GeneOntologyCellularComponentfilopodium membrane

SYNE2 DMD

1.64e-0321602GO:0031527
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

CFAP100 CENPF AKR1B1 DYNC1H1 CCDC40

2.15e-03317605GO:0032838
GeneOntologyCellularComponentcondensed chromosome, centromeric region

CENPF KMT5B RASSF2 CHMP3

2.29e-03193604GO:0000779
GeneOntologyCellularComponentmyosin filament

MYH1 MYO18A

2.33e-0325602GO:0032982
GeneOntologyCellularComponentstriated muscle thin filament

TMOD1 TNNT1

2.72e-0327602GO:0005865
GeneOntologyCellularComponentmyosin II complex

MYH1 MYO18A

2.92e-0328602GO:0016460
GeneOntologyCellularComponentpronucleus

CENPF RAD50

2.92e-0328602GO:0045120
GeneOntologyCellularComponentcytoplasmic region

CFAP100 CENPF AKR1B1 DYNC1H1 CCDC40

3.71e-03360605GO:0099568
GeneOntologyCellularComponentmidbody

USP8 CENPF CHMP3 CEP126

3.79e-03222604GO:0030496
GeneOntologyCellularComponentmyofilament

TMOD1 TNNT1

3.80e-0332602GO:0036379
GeneOntologyCellularComponentlamellipodium

PPP1R9A SYNE2 DMD SNX2

4.30e-03230604GO:0030027
GeneOntologyCellularComponentmicrotubule organizing center

CFAP100 CCDC13 CENPF ITSN2 MYO18A RILPL1 CEP126 DYNC1H1

4.57e-03919608GO:0005815
GeneOntologyCellularComponentnuclear envelope

UBXN4 CENPF SYNE2 CHMP3 RB1CC1 DYNC1H1

5.29e-03560606GO:0005635
DomainSeptin

SEPTIN8 SEPTIN3 SEPTIN14

8.37e-0613593PF00735
DomainG_SEPTIN_dom

SEPTIN8 SEPTIN3 SEPTIN14

8.37e-0613593IPR030379
DomainG_SEPTIN

SEPTIN8 SEPTIN3 SEPTIN14

8.37e-0613593PS51719
DomainSeptin

SEPTIN8 SEPTIN3 SEPTIN14

1.06e-0514593IPR016491
DomainMyosin_tail_1

MYH1 CGN MYO18A

2.36e-0518593PF01576
DomainMyosin_tail

MYH1 CGN MYO18A

2.36e-0518593IPR002928
DomainALDOKETO_REDUCTASE_1

AKR1B10 AKR1B1

4.34e-0410592PS00798
DomainAldo/ket_reductase_CS

AKR1B10 AKR1B1

4.34e-0410592IPR018170
DomainAldo/keto_reductase

AKR1B10 AKR1B1

4.34e-0410592IPR020471
DomainSTI1

ST13P5 ST13

4.34e-0410592SM00727
DomainSTI1_HS-bd

ST13P5 ST13

4.34e-0410592IPR006636
DomainALDOKETO_REDUCTASE_2

AKR1B10 AKR1B1

4.34e-0410592PS00062
DomainALDOKETO_REDUCTASE_3

AKR1B10 AKR1B1

4.34e-0410592PS00063
Domain-

AKR1B10 AKR1B1

1.14e-03165923.20.20.100
DomainNADP_OxRdtase_dom

AKR1B10 AKR1B1

1.29e-0317592IPR023210
DomainAldo_ket_red

AKR1B10 AKR1B1

1.29e-0317592PF00248
DomainAldo/ket_red/Kv-b

AKR1B10 AKR1B1

1.29e-0317592IPR001395
DomainIQ

MYH1 MYO18A IQCG

1.47e-0371593PF00612
DomainMyosin-like_IQ_dom

MYH1 MYO18A

1.62e-0319592IPR027401
Domain-

MYH1 MYO18A

1.62e-03195924.10.270.10
DomainIQ

MYH1 MYO18A IQCG

2.14e-0381593SM00015
DomainActinin_actin-bd_CS

SYNE2 DMD

2.38e-0323592IPR001589
DomainSpectrin

SYNE2 DMD

2.38e-0323592PF00435
DomainACTININ_2

SYNE2 DMD

2.38e-0323592PS00020
DomainACTININ_1

SYNE2 DMD

2.38e-0323592PS00019
DomainTPR_1

CTR9 ST13P5 ST13

2.89e-0390593PF00515
DomainTPR_1

CTR9 ST13P5 ST13

2.89e-0390593IPR001440
DomainIQ_motif_EF-hand-BS

MYH1 MYO18A IQCG

2.89e-0390593IPR000048
DomainIQ

MYH1 MYO18A IQCG

3.18e-0393593PS50096
DomainSpectrin_repeat

SYNE2 DMD

3.77e-0329592IPR002017
DomainSpectrin/alpha-actinin

SYNE2 DMD

4.58e-0332592IPR018159
DomainSPEC

SYNE2 DMD

4.58e-0332592SM00150
DomainP-loop_NTPase

SEPTIN8 MYH1 SEPTIN3 SEPTIN14 MYO18A CHD2 DYNC1H1 RAD50

4.98e-03848598IPR027417
DomainTPR-like_helical_dom

KIFBP CTR9 ST13P5 ST13

6.28e-03233594IPR011990
DomainMyosin_head_motor_dom

MYH1 MYO18A

6.41e-0338592IPR001609
DomainMYOSIN_MOTOR

MYH1 MYO18A

6.41e-0338592PS51456
DomainMyosin_head

MYH1 MYO18A

6.41e-0338592PF00063
DomainMYSc

MYH1 MYO18A

6.41e-0338592SM00242
PathwayREACTOME_STRIATED_MUSCLE_CONTRACTION

TMOD1 DMD TNNT1

1.62e-0435433MM15005
PathwayREACTOME_STRIATED_MUSCLE_CONTRACTION

TMOD1 DMD TNNT1

1.76e-0436433M18647
PathwayWP_STRIATED_MUSCLE_CONTRACTION_PATHWAY

TMOD1 DMD TNNT1

2.07e-0438433M39549
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MYH1 USP8 UBXN4 CENPF CTR9 PPP1R9A SYNE2 ITSN2 ZBTB21 SYCP1 XRN1 MYO18A MAP7D2 CHD2 DMD SIPA1L2 TNNT1 NIPBL

6.93e-111442641835575683
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

SEPTIN8 PPP1R9A AKR1B10 ITSN2 XRN1 MYO18A TMOD1 MAP7D2 EFHD2 RAI14 DMD SIPA1L2 AKR1B1 ST13P5 ST13 DYNC1H1 SNX2

5.57e-101431641737142655
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

SEPTIN8 ITSN2 CGN XRN1 CCT6B MAP7D2 EFHD2 SIPA1L2 DYNC1H1 SNX2 RAD50

4.12e-07853641128718761
Pubmed

Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.

RTF1 SEPTIN8 UBXN4 MYO18A RB1CC1

4.68e-07836459039502
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CCDC13 KIFBP SEPTIN3 CENPF PPP1R9A SYNE2 ZBTB21 EFHD2 NIPBL DYNC1H1 RAD50

1.35e-06963641128671696
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

KIFBP UBXN4 PAXBP1 NDUFAF2 CTR9 SYNE2 MYO18A MAP7D2 RB1CC1 SIPA1L2 ST13 SNX2 EFR3A

2.60e-061487641333957083
Pubmed

Localization of septin proteins in the mouse cochlea.

SEPTIN8 SEPTIN3 SEPTIN14

3.27e-061664322575789
Pubmed

Aldose reductase (AC)n gene polymorphism and susceptibility to diabetic retinopathy in Type 2 diabetes in Caucasians.

AKR1B10 AKR1B1

3.33e-06264215745835
Pubmed

Inhibitor selectivity between aldo-keto reductase superfamily members AKR1B10 and AKR1B1: role of Trp112 (Trp111).

AKR1B10 AKR1B1

3.33e-06264224100137
Pubmed

Opposing roles of the aldo-keto reductases AKR1B1 and AKR1B10 in colorectal cancer.

AKR1B10 AKR1B1

3.33e-06264228929377
Pubmed

Evaluation of an aldo-keto reductase gene signature with prognostic significance in colon cancer via activation of epithelial to mesenchymal transition and the p70S6K pathway.

AKR1B10 AKR1B1

3.33e-06264232628753
Pubmed

Human aldose reductase and human small intestine aldose reductase are efficient retinal reductases: consequences for retinoid metabolism.

AKR1B10 AKR1B1

3.33e-06264212732097
Pubmed

Aldo Keto Reductases AKR1B1 and AKR1B10 in Cancer: Molecular Mechanisms and Signaling Networks.

AKR1B10 AKR1B1

3.33e-06264233945128
Pubmed

Evaluation of compound selectivity of aldo-keto reductases using differential scanning fluorimetry.

AKR1B10 AKR1B1

3.33e-06264228003428
Pubmed

Decreased levels of AKR1B1 and AKR1B10 in cancerous endometrium compared to adjacent non-cancerous tissue.

AKR1B10 AKR1B1

3.33e-06264223146748
Pubmed

Identification and characterization of a novel human aldose reductase-like gene.

AKR1B10 AKR1B1

3.33e-0626429565553
Pubmed

Human aldo-keto reductases 1B1 and 1B10: a comparative study on their enzyme activity toward electrophilic carbonyl compounds.

AKR1B10 AKR1B1

3.33e-06264221329684
Pubmed

St13 protects against disordered acinar cell arachidonic acid pathway in chronic pancreatitis.

ST13P5 ST13

3.33e-06264235562743
Pubmed

Aldo-keto reductases-mediated cytotoxicity of 2-deoxyglucose: A novel anticancer mechanism.

AKR1B10 AKR1B1

3.33e-06264229617059
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

RTF1 SEPTIN8 USP8 KIFBP KMT5B CGN ZBTB21 RAI14 RB1CC1 AKR1B1 DYNC1H1 RAD50

3.39e-061284641217353931
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

USP8 RASSF2 RABGAP1L SYNE2 CGN ZBTB21 XRN1 RAI14 SIPA1L2 SNX2

3.71e-06861641036931259
Pubmed

EVI1 oncoprotein interacts with a large and complex network of proteins and integrates signals through protein phosphorylation.

PPP1R9A RB1CC1 DYNC1H1 GOLGA6L1 RAD50

4.00e-0612864523858473
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SEPTIN8 KIFBP UBXN4 CECR2 ZBTB21 RAI14 CEP126 EFR3A

5.70e-0652964814621295
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

CENPF XRN1 EFHD2 RAI14 DYNC1H1 EFR3A

7.87e-0625664633397691
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

USP8 CGN XRN1 EFHD2 RAI14 RB1CC1 SNX2 EFR3A

9.19e-0656564825468996
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

USP8 RABGAP1L PPP1R9A ITSN2 ANKRD12 SIPA1L2 DYNC1H1

9.99e-0640764712693553
Pubmed

Substrate specificity and catalytic efficiency of aldo-keto reductases with phospholipid aldehydes.

AKR1B10 AKR1B1

9.99e-06364217381426
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

SEPTIN8 MYO18A TMOD1 MAP7D2 RAI14 MAP3K13 SIPA1L2

1.42e-0543064732581705
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

UBXN4 PAXBP1 SEPTIN3 CTR9 PPP1R9A ITSN2 XRN1 EFHD2 RAI14 CHD2 NIPBL EFR3A

1.59e-051497641231527615
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

CENPF PPP1R9A SYNE2 CGN ZBTB21 RB1CC1 NIPBL DYNC1H1 SNX2 RAD50

1.68e-051024641024711643
Pubmed

Myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development.

MYH1 DMD

2.00e-05464228569755
Pubmed

Regulation of Skeletal Muscle Stem Cell Quiescence by Suv4-20h1-Dependent Facultative Heterochromatin Formation.

KMT5B DMD

2.00e-05464226669898
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SEPTIN8 CTR9 SYNE2 RB1CC1

2.07e-058764412465718
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

CENPF SYNE2 CGN XRN1 CHD2 NIPBL DYNC1H1 RAD50

2.60e-0565364822586326
Pubmed

Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4.

UBXN4 SYNE2 XRN1 EFHD2 RAI14

2.78e-0519164531177093
Pubmed

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.

PAXBP1 CENPF SYNE2 DMD RAD50

3.22e-0519764520811636
Pubmed

Comparisons of genomic structures and chromosomal locations of the mouse aldose reductase and aldose reductase-like genes.

AKR1B10 AKR1B1

3.32e-05564210092857
Pubmed

YY1 regulates skeletal muscle regeneration through controlling metabolic reprogramming of satellite cells.

DMD TNNT1

3.32e-05564230979776
Pubmed

Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN.

CGN MYO18A TMOD1 EFHD2 RAI14 DYNC1H1

3.52e-0533464630425250
Pubmed

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.

MYH1 RABGAP1L SYCP1 CHD2 CEP126 LRRD1 SNX2 KCNH5

3.68e-0568664829987050
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

RTF1 YJU2 PAXBP1 CENPF CCT6B RAI14 DYNC1H1

4.02e-0550664730890647
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

KIFBP PPP1R9A ITSN2 ZBTB21

4.02e-0510364410574462
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

SEPTIN8 UBXN4 SEPTIN3 RABGAP1L XRN1 MYO18A MAP7D2 SIPA1L2 ST13P5 ST13

4.15e-051139641036417873
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

RTF1 MYH1 RASSF2 CTR9 CHD2 MAP3K13 ANKRD36C RB1CC1 RAD50

4.19e-0591064936736316
Pubmed

New and novel intrinsic host repressive factors against HIV-1: PAF1 complex, HERC5 and others.

RTF1 CTR9

4.98e-05664222405323
Pubmed

Direct interactions between the Paf1 complex and a cleavage and polyadenylation factor are revealed by dissociation of Paf1 from RNA polymerase II.

RTF1 CTR9

4.98e-05664218469135
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

PPP1R9A CGN RB1CC1 NIPBL DYNC1H1 SNX2

5.33e-0536064633111431
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

CGN XRN1 EFHD2 RAI14 DYNC1H1 SNX2 RAD50

6.71e-0554964738280479
Pubmed

Sequence requirements of the FFAT-like motif for specific binding to VAP-A are revealed by NMR.

RB1CC1 SNX2

6.96e-05764234312846
Pubmed

The parafibromin tumor suppressor protein is part of a human Paf1 complex.

RTF1 CTR9

6.96e-05764215632063
Pubmed

Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a.

RTF1 CTR9

6.96e-05764227749823
Pubmed

Capturing novel mouse genes encoding chromosomal and other nuclear proteins.

RTF1 CECR2

6.96e-0576429701556
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

USP8 SYNE2 MYO18A TMOD1 EFHD2 DMD DYNC1H1 RAD50

7.13e-0575464835906200
Pubmed

Computational and biological analysis of 680 kb of DNA sequence from the human 5q31 cytokine gene cluster region.

SEPTIN8 RAD50

9.27e-0586429149945
Pubmed

Long noncoding RNA lncMREF promotes myogenic differentiation and muscle regeneration by interacting with the Smarca5/p300 complex.

MYH1 DMD

9.27e-05864236200826
Pubmed

Naturally occurring variants of human aldo-keto reductases with reduced in vitro metabolism of daunorubicin and doxorubicin.

AKR1B10 AKR1B1

9.27e-05864220837989
Pubmed

Septin 14 is involved in cortical neuronal migration via interaction with Septin 4.

SEPTIN3 SEPTIN14

9.27e-05864220181826
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

RTF1 YJU2 CTR9 ZBTB21 EFHD2 CHD2 AKR1B1 NIPBL RAD50

9.60e-05101464932416067
Pubmed

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.

USP8 CGN ZBTB21 RAI14 DYNC1H1

1.09e-0425564515324660
Pubmed

Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle.

MYH1 DMD TNNT1

1.10e-045064327597886
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

CCDC13 USP8 SEPTIN3 CTR9 CHMP3 RAI14 RILPL1 NIPBL ST13 DYNC1H1

1.13e-041285641035914814
Pubmed

The human PAF1 complex acts in chromatin transcription elongation both independently and cooperatively with SII/TFIIS.

RTF1 CTR9

1.19e-04964220178742
Pubmed

Association analysis of susceptibility candidate region on chromosome 5q31 for tuberculosis.

SEPTIN8 RAD50

1.19e-04964220485362
Pubmed

The human PAF complex coordinates transcription with events downstream of RNA synthesis.

RTF1 CTR9

1.19e-04964216024656
Pubmed

Superfluous role of mammalian septins 3 and 5 in neuronal development and synaptic transmission.

SEPTIN8 SEPTIN3

1.19e-04964218809578
Pubmed

The HRPT2 tumor suppressor gene product parafibromin associates with human PAF1 and RNA polymerase II.

RTF1 CTR9

1.19e-04964215923622
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

CENPF ZBTB21 XRN1 RAI14 RB1CC1 RAD50

1.21e-0441864634709266
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

UBXN4 CTR9 PPP1R9A SYNE2 CGN RAI14 DMD RB1CC1 EFR3A

1.24e-04104964927880917
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

USP8 PPP1R9A ITSN2 RAI14 DMD SIPA1L2

1.26e-0442164636976175
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

USP8 KIFBP CTR9 RABGAP1L CGN ZBTB21 RAI14 DYNC1H1 CCDC40 RAD50

1.41e-041321641027173435
Pubmed

SHP2 tyrosine phosphatase converts parafibromin/Cdc73 from a tumor suppressor to an oncogenic driver.

RTF1 CTR9

1.49e-041064221726809
Pubmed

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.

ITSN2 MYO18A CHMP3 EFHD2 RAI14 DYNC1H1 RAD50

1.51e-0462664733644029
Pubmed

Analysis of the DNA sequence and duplication history of human chromosome 15.

GOLGA6L6 GOLGA6L22 CHD2

1.54e-045664316572171
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

SEPTIN8 UBXN4 RABGAP1L ST13P5 NIPBL ST13 DYNC1H1 RAD50

1.59e-0484764835235311
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

USP8 KIFBP RASSF2 PPP1R9A CGN SIPA1L2

1.72e-0444664624255178
Pubmed

The MIT domain of UBPY constitutes a CHMP binding and endosomal localization signal required for efficient epidermal growth factor receptor degradation.

USP8 CHMP3

1.81e-041164217711858
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

CGN RAI14 CEP126 SIPA1L2

1.86e-0415364410718198
Pubmed

RNF38 suppress growth and metastasis via ubiquitination of ACTN4 in nasopharyngeal carcinoma.

MYO18A EFHD2 RAI14

2.08e-046264335568845
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

SEPTIN8 MYO18A EFHD2 RAI14 AKR1B1 ST13 DYNC1H1 SNX2 RAD50

2.45e-04114964935446349
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

RTF1 USP8 PAXBP1 CTR9 SYNE2 EFHD2 NIPBL DYNC1H1 SPINK5 RAD50

2.46e-041415641028515276
Pubmed

CTR9/PAF1c regulates molecular lineage identity, histone H3K36 trimethylation and genomic imprinting during preimplantation development.

RTF1 CTR9

2.57e-041364224036311
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

KIFBP PAXBP1 CENPF CTR9 AKR1B1 NIPBL ST13 DYNC1H1 SNX2 RAD50

2.61e-041425641030948266
Pubmed

Analysis of gene expression in the developing mouse retina.

CHMP3 RAI14

2.99e-041464212702772
Pubmed

Defective excitation-contraction coupling is partially responsible for impaired contractility in hindlimb muscles of Stac3 knockout mice.

MYH1 TNNT1

2.99e-041464227184118
Pubmed

Deletion of the Ste20-like kinase SLK in skeletal muscle results in a progressive myopathy and muscle weakness.

MYH1 DMD

2.99e-041464228153048
Pubmed

A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.

KIFBP CTR9 AKR1B10 MYO18A EFHD2 AKR1B1

3.28e-0450364636217030
Pubmed

System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

RTF1 CTR9

3.45e-041564221406692
Pubmed

Six homeoproteins and a Iinc-RNA at the fast MYH locus lock fast myofiber terminal phenotype.

MYH1 TNNT1

3.45e-041564224852826
Pubmed

The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability.

MYO18A TMOD1 EFHD2 RAI14 RAD50

3.50e-0432864523398456
Pubmed

MusTRD can regulate postnatal fiber-specific expression.

MYH1 TNNT1

3.93e-041664216494860
Pubmed

Identification of 40 genes on a 1-Mb contig around the IL-4 cytokine family gene cluster on mouse chromosome 11.

SEPTIN8 RAD50

3.93e-041664210704283
Pubmed

SHP-1 dephosphorylates histone H2B to facilitate its ubiquitination during transcription.

RTF1 CTR9

3.93e-041664235938192
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

SYNE2 MYO18A CCT6B DMD

4.00e-0418764426460568
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

CTR9 XRN1 CCT6B EFHD2 DMD SIPA1L2 SNX2 RAD50

4.06e-0497464828675297
Pubmed

Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families.

UBXN4 RABGAP1L EFHD2 RAI14 SNX2

4.07e-0433964537232246
Pubmed

Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.

USP8 CGN RAI14 DYNC1H1

4.24e-0419064415161933
Pubmed

WNT/β-catenin signaling plays a crucial role in myoblast fusion through regulation of nephrin expression during development.

MYH1 DMD

5.00e-041864230389854
Pubmed

RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells.

RTF1 CTR9

5.00e-041864219410543
Pubmed

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.

YJU2 UBXN4 NDUFAF2 SYNE2 ITSN2 MAP7D2 EFHD2 SNX2

5.06e-04100764834597346
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

PAXBP1 CTR9 ZBTB21 MYO18A NIPBL SNX2 RAD50

5.44e-0477464715302935
InteractionOFD1 interactions

KIFBP RASSF2 XRN1 TMOD1 CEP126 RB1CC1 DYNC1H1 RAD50

1.21e-05347638int:OFD1
InteractionCALD1 interactions

PPP1R9A CGN MYO18A TMOD1 RAI14 ST13P5 ST13

1.85e-05265637int:CALD1
InteractionKCTD13 interactions

SEPTIN8 PPP1R9A ITSN2 XRN1 MYO18A TMOD1 MAP7D2 EFHD2 RAI14 DMD SIPA1L2 AKR1B1 ST13 DYNC1H1 SNX2

1.91e-0513946315int:KCTD13
InteractionSYNPO interactions

PPP1R9A CGN MYO18A TMOD1 RAI14 RB1CC1

2.99e-05192636int:SYNPO
InteractionDBN1 interactions

RABGAP1L PPP1R9A CGN MYO18A TMOD1 RAI14 RB1CC1 NIPBL

4.50e-05417638int:DBN1
InteractionSYCE1 interactions

CFAP100 CENPF RABGAP1L SYCP1 RAD50

4.82e-05127635int:SYCE1
InteractionPPP1CA interactions

USP8 KIFBP PPP1R9A MYO18A CEP126 RB1CC1 CCDC181 ST13 DYNC1H1 RAD50

5.53e-056966310int:PPP1CA
InteractionSTARD13 interactions

SYNE2 CGN ZBTB21 DMD

6.08e-0568634int:STARD13
InteractionSEPTIN12 interactions

SEPTIN8 SEPTIN3 CCT6B

7.19e-0526633int:SEPTIN12
InteractionSEPTIN10 interactions

SEPTIN8 KIFBP SEPTIN3 CENPF SEPTIN14

8.75e-05144635int:SEPTIN10
InteractionPPP1CB interactions

PPP1R9A MYO18A TMOD1 RAI14 RB1CC1 ST13 DYNC1H1 RAD50

1.02e-04469638int:PPP1CB
InteractionMECOM interactions

MYH1 RABGAP1L PPP1R9A RB1CC1 DYNC1H1 GOLGA6L1 RAD50

1.24e-04358637int:MECOM
InteractionKDM1A interactions

CFAP100 KIFBP CENPF RASSF2 RABGAP1L ITSN2 ZBTB21 XRN1 RAI14 RB1CC1 RAD50

1.44e-049416311int:KDM1A
InteractionSEPTIN14 interactions

SEPTIN8 SEPTIN3 SEPTIN14

1.49e-0433633int:SEPTIN14
InteractionYWHAZ interactions

USP8 KMT5B RASSF2 SYNE2 CGN ZBTB21 MYO18A RAI14 CEP126 RB1CC1 SIPA1L2 AKR1B1 DYNC1H1

1.84e-0413196313int:YWHAZ
InteractionNEXN interactions

CECR2 PPP1R9A MYO18A TMOD1

1.89e-0491634int:NEXN
InteractionCDC42 interactions

SEPTIN8 KIFBP UBXN4 PPP1R9A SYNE2 CGN MYO18A RAI14 MAP3K13 RB1CC1 AKR1B1 ST13 EFR3A

1.90e-0413236313int:CDC42
InteractionARMC10 interactions

PPP1R9A MYO18A RB1CC1

2.10e-0437633int:ARMC10
InteractionSEPTIN4 interactions

SEPTIN8 SEPTIN3 SEPTIN14

2.27e-0438633int:SEPTIN4
InteractionLEPR interactions

USP8 XRN1 SNX2

2.46e-0439633int:LEPR
InteractionRDX interactions

CENPF PPP1R9A RAI14 AKR1B1 ST13 SNX2

2.57e-04284636int:RDX
InteractionFGD6 interactions

CTR9 CGN ZBTB21

2.65e-0440633int:FGD6
InteractionYWHAB interactions

USP8 RASSF2 CTR9 CGN ZBTB21 RAI14 RB1CC1 SIPA1L2 ST13 DYNC1H1 RAD50

2.75e-0410146311int:YWHAB
InteractionACTC1 interactions

RTF1 YJU2 PAXBP1 CENPF SYNE2 CCT6B RAI14 DMD DYNC1H1

2.90e-04694639int:ACTC1
InteractionMTMR10 interactions

PPP1R9A CGN RAI14

3.06e-0442633int:MTMR10
Cytoband1q24

RABGAP1L CCDC181

3.58e-04206421q24
GeneFamilySeptins

SEPTIN8 SEPTIN3 SEPTIN14

3.05e-0613413732
GeneFamilyTetratricopeptide repeat domain containing|Paf1/RNA polymerase II complex

RTF1 CTR9

7.48e-0564121029
GeneFamilyAldo-keto reductases

AKR1B10 AKR1B1

5.17e-0415412399
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

KIFBP CTR9 ST13

2.24e-03115413769
GeneFamilyPDZ domain containing

PPP1R9A MYO18A SIPA1L2

4.92e-031524131220
CoexpressionGABRIELY_MIR21_TARGETS

RTF1 UBXN4 SYNE2 ITSN2 RAI14 DMD NIPBL

5.40e-06289627M2196
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

USP8 RABGAP1L SYNE2 ITSN2 RAI14 RB1CC1 NIPBL SNX2 RAD50

2.27e-05656629M18979
CoexpressionWANG_LMO4_TARGETS_DN

USP8 NDUFAF2 CGN DMD RB1CC1 SIPA1L2 DYNC1H1

2.28e-05361627M12674
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000

SEPTIN3 CENPF CECR2 RABGAP1L SYNE2 CGN TMOD1 MAP7D2 CHD2 DMD SIPA1L2 TNNT1

2.72e-059836312Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_200

CENPF CECR2 SYCP1 MAP7D2 IQCG

5.79e-05139635gudmap_dev gonad_e13.5_M_GermCell_Oct_200
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1

SEPTIN8 CENPF CECR2 SYNE2 ITSN2 MYO18A CHD2 RB1CC1 SIPA1L2 NIPBL

9.26e-057806310Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

RTF1 UBXN4 CENPF SYNE2 ANKRD12 RB1CC1 NIPBL RAD50

3.84e-1019863876d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell(00)_Basal-(2)_GFP_FOXI1|(00)_Basal / shred by cell type by condition

RTF1 UBXN4 SYNE2 RAI14 ANKRD12 RB1CC1 NIPBL RAD50

4.00e-1019963819674e1eaeb51e4196d847cb62aa437c852951d3
ToppCell(02)_MMP9/10+-(2)_GFP_FOXI1|(02)_MMP9/10+ / shred by cell type by condition

RTF1 UBXN4 SYNE2 ITSN2 ANKRD12 RB1CC1 NIPBL RAD50

4.00e-1019963818a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

RTF1 UBXN4 SYNE2 ITSN2 ANKRD12 RB1CC1 NIPBL RAD50

4.00e-10199638c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PAXBP1 SYNE2 ITSN2 XRN1 CHD2 ANKRD12 NIPBL DYNC1H1

4.16e-1020063812f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell(08)_Brush+PNEC-(2)_GFP_FOXI1|(08)_Brush+PNEC / shred by cell type by condition

RTF1 SYNE2 RAI14 ANKRD12 RB1CC1 NIPBL RAD50

1.05e-09138637817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

SYNE2 CHD2 ANKRD12 ANKRD36C RB1CC1 NIPBL DYNC1H1

9.03e-09188637ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

UBXN4 SYNE2 ANKRD12 CEP126 RB1CC1 NIPBL RAD50

1.34e-0819963761b1ed2db71b96157b92b7535d1955a4033098da
ToppCell(04)_Interm._basal>secr.-(2)_GFP_FOXI1|(04)_Interm._basal>secr. / shred by cell type by condition

RTF1 UBXN4 SYNE2 ANKRD12 RB1CC1 NIPBL RAD50

1.34e-0819963753ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCell(01)_IL1RL1+-(2)_GFP_FOXI1|(01)_IL1RL1+ / shred by cell type by condition

RTF1 UBXN4 SYNE2 ANKRD12 RB1CC1 NIPBL RAD50

1.34e-08199637a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

KIFBP FAM13C MYO18A CHD2 ANKRD12 DYNC1H1

1.92e-07177636e8ab340b20cd41554c3841fe980e078e878af35f
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP8 CECR2 ITSN2 XRN1 SLAMF7 NIPBL

2.26e-07182636f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP8 CECR2 ITSN2 XRN1 SLAMF7 NIPBL

2.49e-071856367adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

UBXN4 SYNE2 ANKRD12 RB1CC1 NIPBL RAD50

3.82e-07199636fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell(05)_Secretory-(2)_GFP_FOXI1|(05)_Secretory / shred by cell type by condition

RTF1 UBXN4 SYNE2 ANKRD12 RB1CC1 RAD50

3.82e-07199636d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP100 GOLGA6L22 CEP126 CCDC40 IQCG

5.65e-061806351f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCell21-Trachea-Epithelial-Multiciliated_precursor|Trachea / Age, Tissue, Lineage and Cell class

ZBTB21 CEP126 CCDC181 CCDC40 IQCG

5.96e-061826356e35892fa959ee31591850ded8f1088195ddeb01
ToppCellCOVID-19_Mild-gd_T|COVID-19_Mild / Disease condition and Cell class

SYNE2 EFHD2 ARHGAP25 SLAMF7 SIPA1L2

6.12e-06183635f593a89b0aa8fffdfa403769916facfd30358521
ToppCelldroplet-Bladder-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RTF1 UBXN4 SYNE2 ANKRD12 NIPBL

6.80e-06187635663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCelltumor_Lung-Epithelial_cells-tS3|Epithelial_cells / Location, Cell class and cell subclass

CFAP100 CEP126 CCDC181 CCDC40 IQCG

6.80e-061876353cea677279e71fdb9879530dea10a5e6393beacd
ToppCelldroplet-Tongue-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RTF1 UBXN4 SYNE2 CHD2 NIPBL

6.97e-06188635d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCellPND28-Epithelial|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PPP1R9A CGN CCDC181 SPINK5 IQCG

7.34e-0619063589e5ddd830f70429d5b2fbaf8d0790b033450aa7
ToppCellCiliated-cil-3|World / Class top

CFAP100 CCDC13 CCDC181 CCDC40 IQCG

7.72e-061926354989ebb8812b8af1870599acd932849122c05a29
ToppCellASK452-Epithelial-Ciliated|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

CFAP100 CCDC13 CEP126 CCDC181 IQCG

8.12e-061946355aeb44657ab6f61b1abf98af28d3397d8e44c1aa
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CFAP100 CEP126 CCDC181 CCDC40 IQCG

8.54e-0619663527b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCell(05)_Ciliated|World / shred by cell type and Timepoint

CFAP100 CCDC13 CCDC181 CCDC40 IQCG

8.75e-06197635fee3cd16af8eea697cd64e8f64af505aaa2ac4b0
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP100 SYNE2 CEP126 DMD CCDC40

8.75e-0619763574a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

RTF1 CHD2 ANKRD12 ANKRD36C RAD50

8.75e-061976350fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCellsystemic_lupus_erythematosus-flare|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SYNE2 XRN1 ARHGAP25 CHD2 ANKRD12

8.97e-061986354c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CFAP100 CENPF CEP126 CCDC181 IQCG

8.97e-061986351847ce8c344c8a3e50f3cbbf758a38aba69f85b0
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP100 CEP126 CCDC181 CCDC40 IQCG

9.41e-06200635cc906ff02fd335ff633b3b97afceb670494f910a
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP100 CEP126 CCDC181 CCDC40 IQCG

9.41e-0620063579e59ab31d3d3385b1b072dc75508af9546c2e1b
ToppCellBronchus_Control_(B.)-Epithelial-TX-Ciliated|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

CFAP100 CEP126 CCDC181 CCDC40 IQCG

9.41e-062006356a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP100 CEP126 CCDC181 CCDC40 IQCG

9.41e-06200635873def69bf55ccbfc944bc10c5afc06be019c312
ToppCellCOVID-19|World / Disease, condition lineage and cell class

SYNE2 XRN1 ANKRD12 NIPBL DYNC1H1

9.41e-062006357dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_activated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

MYH1 KMT5B SYNE2 SLAMF7

2.38e-051186345f72022f4be3fb7ccec86dc05d37572833028886
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_activated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MYH1 KMT5B SYNE2 SLAMF7

2.38e-05118634053c0986051e36fdc4c48b8067c137b6299b2f1b
ToppCellControl-Lymphoid_T/NK-NK_activated|Control / Disease group, lineage and cell class

MYH1 KMT5B SYNE2 SLAMF7

2.46e-05119634a258d91ac90d4174b6f203d7f96ba6e57c6003e7
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_activated|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MYH1 KMT5B SYNE2 SLAMF7

2.46e-0511963428d6b0e9dda2fe4ca94ae9b95b7261618d0d9877
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_activated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MYH1 KMT5B SYNE2 SLAMF7

2.46e-051196340fdd5b093ac20a4bda0f7b623808eb3ad0bf68e2
ToppCell3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

SYNE2 CHD2 ANKRD12 ANKRD36C

6.23e-05151634999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCellPND03-Immune-Immune_Myeloid-DC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEPTIN3 RASSF2 EFHD2 SLAMF7

7.98e-05161634f50e91f8363f20bb7c565aaca4d4961d3fe4b5b5
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

SYNE2 CHD2 ANKRD12 ANKRD36C

8.18e-05162634b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCelldroplet-Fat-SCAT-30m-Lymphocytic-B_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 RABGAP1L CCT6B AKR1B1

8.98e-051666344b31d2755108b2815316411a38bfb11fd30ef98a
ToppCelldroplet-Fat-SCAT-30m-Lymphocytic-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 RABGAP1L CCT6B AKR1B1

8.98e-0516663467370c49d7aedcb4eca802095f06b30f6bbf8919
ToppCelldroplet-Fat-SCAT-30m-Lymphocytic|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 RABGAP1L CCT6B AKR1B1

8.98e-051666347f4e5976ede6478636aa567d6fc2b56ff7295fb8
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

CEP126 CCDC181 CCDC40 IQCG

9.20e-0516763426cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCellPND14-Immune-Immune_Myeloid-Dendritic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEPTIN3 CENPF SLAMF7 SIPA1L2

9.41e-051686349b8a74abb83c64f0b5829dcb4275f722c82b45dc
ToppCellPND14-Immune-Immune_Myeloid-Dendritic-cDC1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEPTIN3 CENPF SLAMF7 SIPA1L2

9.41e-051686344b152b8d0f4a66faf664dfacb7914b18d60ce64a
ToppCellPND14-Immune-Immune_Myeloid-Dendritic-cDC1-cDC1_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEPTIN3 CENPF SLAMF7 SIPA1L2

9.41e-05168634c3169ad8f4130ef18777ed86770bb722ffb5db85
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CEP126 DMD CCDC181 IQCG

9.63e-051696348bca402e144819cb9a8d431d6bf9429be2fff6d6
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231|Adult / Lineage, Cell type, age group and donor

CECR2 SYNE2 RAI14 MAP3K13

9.85e-05170634269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEPTIN3 CENPF EFHD2 SLAMF7

9.85e-051706349e94fa0d05abed3438b28296a293767096d517d6
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

SYNE2 CHD2 ANKRD12 ANKRD36C

1.01e-041716342e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellfacs-Trachea-nan-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP100 CCDC181 CCDC40 IQCG

1.13e-04176634ed788a5969edfd1199828ca5b0dd34e7f29c4d30
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAXBP1 KMT5B XRN1 DMD

1.13e-04176634749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RABGAP1L ARHGAP25 SLAMF7 SNX2

1.15e-04177634c506b8fd9a550e6cf93b64a1f7eed2543224a140
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RABGAP1L ARHGAP25 SLAMF7 SNX2

1.15e-04177634840eaac045ada42cae0ab81177d1d0ae55a65633
ToppCellPBMC-Severe-cDC_11|Severe / Compartment, Disease Groups and Clusters

SEPTIN3 CECR2 DMD SLAMF7

1.18e-041786340667abc05eb2254710b9c648c65b7cfdfe7831b7
ToppCellCiliated_cells-A-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CFAP100 CEP126 CCDC181 CCDC40

1.20e-041796340e6c22de2e3fb0ff23b3301863cf4011c5c59dff
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFAP100 CCDC181 CCDC40 IQCG

1.20e-04179634d4efbc34f52136039b96451fd0b0a0ad164197c6
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFAP100 CCDC181 CCDC40 IQCG

1.20e-041796348a66d197a2f55d763ff7ef0bec89ee96f59c3937
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CENPF EFHD2 ARHGAP25 KCNH5

1.20e-04179634d3d3a9afaac28fa4f2c448c73d79bcbbbea088d7
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RABGAP1L ITSN2 SLAMF7 SNX2

1.23e-04180634b83d067dee641941c596e4a25d81327931b6ad61
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Bcl11b-Inhibitory_Gad1Gad2_Id2.Bcl11b_(Interneuron,_Neurogliaform2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYH1 CCT6B TNNT1

1.23e-0468633cfd75c373e10b3761666ccd445ba74755efeb95f
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Bcl11b|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYH1 CCT6B TNNT1

1.23e-0468633c25fb921dc83eecdc337353894829ae6b5192353
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Bcl11b-Inhibitory_Gad1Gad2_Id2.Bcl11b_(Interneuron,_Neurogliaform2)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYH1 CCT6B TNNT1

1.23e-0468633712f5f4d3a1e0c0db1a340332876206b93bdac31
ToppCellP03-Epithelial-airway_epithelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CFAP100 CCDC13 CCDC181 CCDC40

1.25e-041816341ea21d860d4d7abab3e21e130a16d044006656ee
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP100 CCDC13 CEP126 CCDC40

1.25e-04181634dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

SYNE2 CHD2 ANKRD12 ANKRD36C

1.25e-04181634f2315414e714ac86211546a935660c4be6e85f1b
ToppCellCiliated_cells-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

CFAP100 CEP126 CCDC181 IQCG

1.28e-04182634e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SYNE2 EFHD2 ARHGAP25 SLAMF7

1.31e-04183634983ca1342ddd365e1f1df32a456394b002b10e41
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CECR2 PPP1R9A RAI14 MAP3K13

1.31e-041836346847c1252d6bb105524f812658112517fd351eab
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

RABGAP1L SYNE2 XRN1 CHD2

1.31e-041836348f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCelldroplet-Lung-LUNG-30m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP100 MAP3K13 CCDC40 IQCG

1.31e-041836343991830726d05cf19606d540de04093985b7bdeb
ToppCelldroplet-Lung-LUNG-30m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP100 MAP3K13 CCDC40 IQCG

1.31e-04183634cc844f54c7564bf432b179ca63bc7c4b9b8cfdd9
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP8 ITSN2 XRN1 NIPBL

1.34e-041846341154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP100 CCDC181 CCDC40 IQCG

1.34e-04184634797b6a6d6f6aafae98f75ca8bffe8263f8d3ff9b
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP100 CCDC181 CCDC40 IQCG

1.34e-0418463477d5b60a20b277f589b18f7a131142a7ef2dac17
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

CECR2 PPP1R9A RAI14 MAP3K13

1.36e-04185634673f0c688ae6984bc8027df2da335787924f4137
ToppCellBrain_organoid-organoid_Kanton_Nature|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.

SEPTIN3 KMT5B SYNE2 ANKRD36C

1.36e-04185634857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCell15-Trachea-Epithelial-Multiciliated_precursor|Trachea / Age, Tissue, Lineage and Cell class

CENPF ZBTB21 CCDC181 IQCG

1.36e-041856349a8b8360d99375b726ca8e3c9a3f9b08919892d7
ToppCellnucseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RABGAP1L XRN1 ANKRD12 SLAMF7

1.36e-041856343b77bc49cd3740acc025e162a36282ac09e12198
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

CFAP100 CCDC13 CEP126 CCDC40

1.36e-0418563430f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellP28-Epithelial-alveolar_epithelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RABGAP1L PPP1R9A CGN TMOD1

1.36e-041856345bb513e569f3a197d55ae2ca683e202daebabeac
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

FAM13C RABGAP1L DMD TNNT1

1.36e-041856346baccb26f999145e51b91d94315bf8d4655bef31
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP100 CEP126 CCDC181 CCDC40

1.39e-0418663476033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellCiliated-cil-1|World / Class top

CFAP100 CCDC181 CCDC40 IQCG

1.39e-04186634283de646a0e8a322c42a714ae19db9918011146e
ToppCellfacs-Lung-18m-Epithelial-alveolar_epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPP1R9A CGN TMOD1 SPINK5

1.39e-04186634c7214e762b3b48197fdd0b36a50a4de2550a888f
ToppCellPND14-Epithelial-Epithelial_Airway|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP100 CCDC181 CCDC40 IQCG

1.42e-041876341399c703505211c510b3f14c7a2aa9930566c473
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP100 CCDC13 CCDC40 IQCG

1.42e-0418763404dba2ed09ee4180830bdf0191921696697ea234
ToppCellCiliated_cells-B-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CFAP100 CEP126 CCDC181 CCDC40

1.42e-041876342b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

USP8 PPP1R9A RAI14 SPINK5

1.42e-041876346ab51e17a7782c2ae6394cad813dc3a2cde70c89
ToppCellfacs-Lung-18m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPP1R9A CGN TMOD1 SPINK5

1.42e-04187634a5318c888b334e8695f38971a7d100b93cdaf04b
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PAXBP1 CECR2 SYNE2 CGN

1.42e-0418763458d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellfacs-Lung-EPCAM-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP100 CCDC13 CCDC40 IQCG

1.42e-04187634805dafe22f835ece4dd091d8030d0a63b52a48dd
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

USP8 PPP1R9A RAI14 SPINK5

1.42e-04187634e176b5b051690f840f3b12c8f7c4cc10cbe2bbae
ToppCellfacs-Lung-18m-Epithelial-alveolar_epithelial-type_II_pneumocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPP1R9A CGN TMOD1 SPINK5

1.42e-0418763464ba0df991eab8b2632751805d758c5f2711f4d7
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

RABGAP1L RILPL1 DMD TNNT1

1.45e-041886346d249fe92d51a19da19ec14bb2262d394255d577
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SYNE2 EFHD2 ANKRD36C SLAMF7

1.45e-04188634f8e6247bedc0ba494c5bb551539cb8ba5a97f557
Drugoracin

AKR1B10 TNNT1 AKR1B1

6.85e-0614623CID000160047
DrugPentanones

AKR1B10 AKR1B1

7.30e-062622ctd:D010422
Drug4-hydroxyretinal

AKR1B10 AKR1B1

7.30e-062622ctd:C057180
Drug4-oxoretinaldehyde

AKR1B10 AKR1B1

7.30e-062622ctd:C099660
Drugpropioin

AKR1B10 AKR1B1

7.30e-062622ctd:C523189
Drugdehydroretinal

AKR1B10 AKR1B1

7.30e-062622ctd:C017184
Drug2,4-hexadienal

AKR1B10 AKR1B1

2.18e-053622ctd:C079389
DrugAcetoin

AKR1B10 AKR1B1

2.18e-053622ctd:D000093
Drug2,3-butylene glycol

AKR1B10 AKR1B1

2.18e-053622ctd:C026978
Drugnegamycin

DMD SLAMF7

2.18e-053622CID000036458
Drug5-Isothiocyanatoalrestatin

AKR1B10 AKR1B1

4.36e-054622CID000124861
Drug5-azidoalrestatin

AKR1B10 AKR1B1

4.36e-054622CID000128442
Drug5-(3-Thienyl)tetrazol-1-yl)acetic acid

AKR1B10 AKR1B1

4.36e-054622CID003035658
DrugFR-62765

AKR1B10 AKR1B1

4.36e-054622CID000128354
DrugM7HEQ

AKR1B10 AKR1B1

4.36e-054622CID006452329
Drug2,5-DHBQOP

AKR1B10 AKR1B1

4.36e-054622CID000069213
DrugNAP-HEX-Q

AKR1B10 AKR1B1

4.36e-054622CID005487149
DrugWF-2421

AKR1B10 AKR1B1

4.36e-054622CID000195567
Drugdanshenol B

AKR1B10 AKR1B1

4.36e-054622CID003083515
Drug4-chloro-3-hydroxybutanoate

AKR1B10 AKR1B1

4.36e-054622CID010129995
Drugiodomethanesulfonamide

AKR1B10 AKR1B1

4.36e-054622CID000519939
Drugsalviaflaside

AKR1B10 AKR1B1

4.36e-054622CID006438919
Drugmatteuorienate A

AKR1B10 AKR1B1

4.36e-054622CID000190958
Drug2-chloropropionate

ZBTB21 RB1CC1 DYNC1H1

5.37e-0527623CID000011734
DrugM79175

AKR1B10 AKR1B1

7.26e-055622CID000115090
Drugxanthone-2

AKR1B10 AKR1B1

7.26e-055622CID005384285
DrugAC1NE042

AKR1B10 AKR1B1

7.26e-055622CID004634410
DrugAC1L4VGL

AKR1B10 AKR1B1

7.26e-055622CID000213726
Drug4-chloro-3-nitrobenzaldehyde

AKR1B10 AKR1B1

7.26e-055622CID000085505
Drug2,3-hexanedione

AKR1B10 AKR1B1

7.26e-055622ctd:C043231
DrugICI 105552

AKR1B10 AKR1B1

7.26e-055622CID000133677
Drug2-(2,3,6-Trihydroxy-4-carboxyphenyl)ellagic acid

AKR1B10 AKR1B1

7.26e-055622CID006918808
DrugICI 222155

AKR1B10 AKR1B1

7.26e-055622CID000195716
DrugDN-108

AKR1B10 AKR1B1

7.26e-055622CID000183791
DrugAD-5467

AKR1B10 AKR1B1

7.26e-055622CID000197383
DrugBAL-ARI8

AKR1B10 AKR1B1

7.26e-055622CID000130098
Drugphenanthrene trans-1,2-dihydrodiol

AKR1B10 AKR1B1

1.09e-046622CID000115062
DrugICI 215918

AKR1B10 AKR1B1

1.09e-046622CID000129688
DrugAC1L28UN

AKR1B10 AKR1B1

1.09e-046622CID000068017
DrugM16287

AKR1B10 AKR1B1

1.09e-046622CID000188399
Drugp225

AKR1B10 AKR1B1

1.09e-046622CID000014589
DrugADN-138

AKR1B10 AKR1B1

1.09e-046622CID000127323
DrugBAPSG

AKR1B10 AKR1B1

1.09e-046622CID000130998
Drug1,2,4-triazol-3-one

AKR1B10 AKR1B1

1.09e-046622CID011073339
Drugcapillarisin

AKR1B10 AKR1B1

1.09e-046622CID005281342
Drug3,5-dichlorosalicylic acid

AKR1B10 AKR1B1

1.09e-046622CID000009445
Drugmyrciacitrin I

AKR1B10 AKR1B1

1.52e-047622CID000183137
Drugfriedelane

AKR1B10 AKR1B1

1.52e-047622CID000634354
Drug4-chlorobenzaldehyde

SLAMF7 AKR1B1

1.52e-047622CID000007726
Drug3-formylbenzoic acid

AKR1B10 AKR1B1

1.52e-047622CID000012077
Drugtetramethylene glutaric acid

AKR1B10 AKR1B1

1.52e-047622CID000085558
Drugguaijaverin

AKR1B10 AKR1B1

1.52e-047622CID005317847
Drugdesmanthin-1

AKR1B10 AKR1B1

1.52e-047622CID005316590
DrugPerphenazine [58-39-9]; Down 200; 10uM; PC3; HG-U133A

RTF1 SEPTIN8 CENPF RB1CC1 NIPBL

1.91e-041956251956_DN
DrugAtractyloside potassium salt [102130-43-8]; Down 200; 5uM; PC3; HT_HG-U133A

RTF1 PPP1R9A CCT6B ANKRD12 NIPBL

1.91e-041956257393_DN
Drugerythritol 4-phosphate

AKR1B10 AKR1B1

2.02e-048622CID000192838
Drug4-hydroxynonanoate

AKR1B10 AKR1B1

2.02e-048622CID000134653
DrugRisarestat

AKR1B10 AKR1B1

2.02e-048622CID000133264
Drug6-pyridoxyllysine

AKR1B10 AKR1B1

2.02e-048622CID000160700
Drugpropranolol glycol

AKR1B10 AKR1B1

2.02e-048622CID000037369
Drug1,2-diaminoguanidine

AKR1B10 AKR1B1

2.02e-048622CID000170039
Drug20-CHO-LTB4

AKR1B10 AKR1B1

2.02e-048622CID006449839
DrugCP-166,572

AKR1B10 AKR1B1

2.02e-048622CID000132302
Drugalcophosphamide

AKR1B10 AKR1B1

2.02e-048622CID000098612
Drugeutypine

AKR1B10 AKR1B1

2.02e-048622CID000129326
DrugSG-210

AKR1B10 AKR1B1

2.02e-048622CID000132542
DrugNSC633676

AKR1B10 AKR1B1

2.02e-048622CID000133894
Drug3 Na

AKR1B10 AKR1B1

2.02e-048622CID000157838
DrugMetanephrine hydrochloride DL [881-95-8]; Down 200; 17.2uM; PC3; HG-U133A

RTF1 PPP1R9A ANKRD12 RB1CC1 NIPBL

2.10e-041996251933_DN
DrugAL3152

AKR1B10 AKR1B1

2.59e-049622CID000159501
DrugAC1Q5HJP

AKR1B10 AKR1B1

2.59e-049622CID000000067
Drug3-deoxyfructose

AKR1B10 AKR1B1

2.59e-049622CID003080627
Drugpotassium amyl xanthate

AKR1B10 AKR1B1

2.59e-049622CID000017635
Drugmetyrapol

AKR1B10 AKR1B1

2.59e-049622CID000161210
DrugB0683

MYH1 MYO18A DMD TNNT1

2.94e-04117624CID006398969
Drugoxovanadium

MYH1 DMD TNNT1 DYNC1H1

3.23e-04120624CID000024411
Drugmycaminose

AKR1B10 AKR1B1

3.24e-0410622CID000160504
Drug2,3-hexanedione

AKR1B10 AKR1B1

3.24e-0410622CID000019707
DrugHexanones

AKR1B10 AKR1B1

3.24e-0410622ctd:D006588
Drug3-fluoro-3-deoxy-D-glucose

AKR1B10 AKR1B1

3.24e-0410622CID000122305
Druglys-val

AKR1B10 AKR1B1

3.24e-0410622CID000140709
DrugGlyceraldehyde

AKR1B10 AKR1B1

3.24e-0410622ctd:D005985
DrugDihydroxydihydrobenzopyrenes

AKR1B10 AKR1B1

3.95e-0411622ctd:D004101
Drugchlordecone alcohol

AKR1B10 AKR1B1

3.95e-0411622CID000013946
DrugNSC 60462

AKR1B10 AKR1B1

3.95e-0411622CID000097943
Drugsorbitol-3-phosphate

AKR1B10 AKR1B1

4.73e-0412622CID000129544
DrugAL-4114

AKR1B10 AKR1B1

4.73e-0412622CID000164424
DrugAC1MRDQ4

AKR1B10 AKR1B1

4.73e-0412622CID003491289
Drugpurealin

MYH1 MYO18A DYNC1H1

5.33e-0458623CID006419303
Drugbendazac

ZBTB21 AKR1B1

5.58e-0413622CID000002313
Drugbefunolol

AKR1B10 AKR1B1

5.58e-0413622CID000002309
DrugPNAP

AKR1B10 AKR1B1

5.58e-0413622CID000007487
Drug4-formyl-benzoate

AKR1B10 AKR1B1

5.58e-0413622CID000012088
Drug2-hexenal

AKR1B10 AKR1B1

5.58e-0413622ctd:C051750
Drugacetohexamide

AKR1B10 AKR1B1

5.58e-0413622CID000001989
DrugNSC339663

MYH1 SYNE2 ITSN2 SYCP1 MYO18A

5.96e-04250625CID000003892
Diseasealdose reductase measurement

AKR1B10 AKR1B1

2.35e-054592EFO_0801364
Diseasedrug use measurement, quality of life during menstruation measurement

SYCP1 KCNH5

8.20e-057592EFO_0007010, EFO_0009366
Diseasewhite matter growth measurement

AKR1B10 AKR1B1

1.40e-049592EFO_0009335
DiseaseMalignant neoplasm of breast

MYH1 CENPF SYNE2 ITSN2 MAP7D2 MAP3K13 DMD RB1CC1 NIPBL

2.65e-041074599C0006142
DiseaseMicrocephaly

KIFBP CENPF DYNC1H1

3.32e-0467593C0025958
DiseaseMalformations of Cortical Development

KIFBP DYNC1H1

3.52e-0414592C1955869
DiseaseCortical Dysplasia

KIFBP DYNC1H1

3.52e-0414592C0431380
Diseaselevel of Sphingomyelin (d32:1) in blood serum

SYNE2 KCNH5

5.24e-0417592OBA_2045173
Diseasedilated cardiomyopathy (implicated_via_orthology)

MYH1 CENPF DMD

5.59e-0480593DOID:12930 (implicated_via_orthology)
Diseaseinosine measurement

DMD KCNH5

6.58e-0419592EFO_0010503
Diseaseintrinsic cardiomyopathy (implicated_via_orthology)

CCT6B TNNT1

8.05e-0421592DOID:0060036 (implicated_via_orthology)
DiseaseSevere Congenital Microcephaly

KIFBP DYNC1H1

1.76e-0331592C3853041
Diseaseclopidogrel metabolite measurement

MYO18A CCT6B

1.99e-0333592EFO_0007966
DiseaseMicrolissencephaly

KIFBP DYNC1H1

1.99e-0333592C1956147

Protein segments in the cluster

PeptideGeneStartEntry
DIQREEEKVKRSVKD

CHMP3

36

Q9Y3E7
EKIQEKAVKREDLFI

AKR1B10

61

O60218
EKVNAIEREKAEKFR

DMD

761

P11532
QRITDERKREEIKIK

DMD

1836

P11532
SFREEKIKDLKEERE

ANKRD12

761

Q6UB98
IEKQKRKEEEEERQI

CECR2

326

Q9BXF3
EEQEKEKRRLVIEKF

EFR3A

741

Q14156
EKLREQVVKREELFI

AKR1B1

61

P15121
QVIIEDRIEKERSKK

IQCG

371

Q9H095
KHEEREIKERIERVK

ST13P5

241

Q8NFI4
EIKERIERVKKAQEE

ST13P5

246

Q8NFI4
EIKERIERVKKAREE

ST13

246

P50502
EKVRELEEKLVEREK

RAI14

551

Q9P0K7
FIQKLQEEEDREVKK

RASSF2

286

P50749
KRNEELKEVEEERKQ

RAD50

1026

Q92878
EKIQEEERKAEEKQR

ITSN2

726

Q9NZM3
IIKKQDEQIERFEKI

ANKRD36C

1751

Q5JPF3
LKEFKLEREVVEKEL

RB1CC1

1246

Q8TDY2
DERDEKILEKIFKIV

LRRD1

756

A4D1F6
AVEEKRKQKLREEEE

MAP7D2

111

Q96T17
VFQKENEERKRKEEE

SPINK5

671

Q9NQ38
KGRQEELKEVIERFK

KMT5B

131

Q4FZB7
FRKISDVKKEEEERL

KCNH5

676

Q8NCM2
KKRLQQEFEDKLEVE

MYO18A

1386

Q92614
IERERFSKEVQDKDK

NIPBL

486

Q6KC79
KIREQEEKRQEEEKI

GOLGA6L1

391

Q8N7Z2
EKIREQEEKIREQKE

GOLGA6L1

571

Q8N7Z2
EKIREQEEKIREQEK

GOLGA6L6

411

A8MZA4
IREQEKKIREQEEKI

GOLGA6L6

651

A8MZA4
KKIREQEEKIREQEE

GOLGA6L6

656

A8MZA4
EKIREQEEKIREQKE

GOLGA6L22

616

H0YM25
EKIREQEKKIREQEE

GOLGA6L22

686

H0YM25
EKKIREQEEKIREQE

GOLGA6L22

741

H0YM25
IEELKRQLEEEIKAK

MYH1

1316

P12882
DDDEKRRIVFSVKEK

PAXBP1

266

Q9Y5B6
KQRLVETEEEKRKQE

RABGAP1L

66

B7ZAP0
KFRAEEVAIKKVREQ

MAP3K13

186

O43283
EEERRKIEEEKEKKR

CCDC181

356

Q5TID7
IEKLRVRIEADEKKQ

CENPF

2121

P49454
QRKKVEEEERQKELE

CHD2

1051

O14647
EEKRKEQEEKEHQIR

CEP126

86

Q9P2H0
ETERIRAEIEKKKQD

CCDC40

426

Q4G0X9
DVLQRELEELKKKFE

CCDC13

336

Q8IYE1
LLKEQEEKRLREKEE

CTR9

856

Q6PD62
QVKIEQAERAKEKER

CFAP100

526

Q494V2
ERIQKIKREKEERGE

DYNC1H1

2106

Q14204
RFEEEIKAEQEERKK

EFHD2

206

Q96C19
EEKLTEQERSKRFEK

KIFBP

191

Q96EK5
DIEEIVKEKERFRKA

RTF1

491

Q92541
IRKEVGRFEKERVKD

SNX2

471

O60749
KAERKFIEDRVQKII

CCT6B

261

Q92526
FIEDRVQKIIDLKDK

CCT6B

266

Q92526
FEQRKKEEEELVALK

TNNT1

86

P13805
QEEIRKLEEEKKQLE

SEPTIN14

386

Q6ZU15
KKRIAEIEIVKEEFN

SYNE2

1571

Q8WXH0
VSIRREKVEDAKEKE

SIPA1L2

511

Q9P2F8
LKRKIRKFEEKFEQE

FAM13C

296

Q8NE31
RKVEELQRKLDEEVK

CGN

366

Q9P2M7
EKFQRKLIDIVRERE

ZBTB21

616

Q9ULJ3
LKEVVDKQRDEIRAK

RILPL1

166

Q5EBL4
LEKQAKEFKDREDLV

TMOD1

71

P28289
EKSEFKQRVRKELEV

SEPTIN3

216

Q9UH03
QLEIEREEKEKLKRE

SYCP1

766

Q15431
EKRNKALEEEVKEFV

ARHGAP25

621

P42331
IVEKIEEEVEKCKQR

XRN1

1056

Q8IZH2
IREKRIVEAANKKEV

NDUFAF2

46

Q8N183
KRKVEEKRRELEEET

SEPTIN8

381

Q92599
KRERQEEYIEEKKRV

SLAMF7

251

Q9NQ25
EKLLEEEEKRVQKER

YJU2

111

Q9BW85
EEEQREIKKEIERRK

UBXN4

216

Q92575
AEVRKKLEEKDRQEE

USP8

116

P40818
FIKRQEAERKKIEDL

PPP1R9A

781

Q9ULJ8