Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix structural constituent	MFAP2 RELN FBLN2 VWF EFEMP2 NID1 EDIL3 ZP2 LTBP4 MUC4 MUC6	7.41e-10	188	89	11	GO:0005201
GeneOntologyMolecularFunction	ubiquitin-protein transferase activity	UBR1 RNF113B TRAF2 TRIM2 RNF113A CHFR RNF34 C10orf90 HERC2 UBE2E3 RNF208	8.12e-06	473	89	11	GO:0004842
GeneOntologyMolecularFunction	ubiquitin-like protein transferase activity	UBR1 RNF113B TRAF2 TRIM2 RNF113A CHFR RNF34 C10orf90 HERC2 UBE2E3 RNF208	1.70e-05	512	89	11	GO:0019787
GeneOntologyMolecularFunction	aminoacyltransferase activity	UBR1 RNF113B TRAF2 TRIM2 RNF113A CHFR RNF34 C10orf90 HERC2 UBE2E3 RNF208	2.42e-05	532	89	11	GO:0016755
GeneOntologyMolecularFunction	ubiquitin protein ligase activity	UBR1 RNF113B TRIM2 RNF113A CHFR RNF34 C10orf90 HERC2 RNF208	4.20e-05	372	89	9	GO:0061630
GeneOntologyMolecularFunction	ubiquitin-like protein ligase activity	UBR1 RNF113B TRIM2 RNF113A CHFR RNF34 C10orf90 HERC2 RNF208	7.07e-05	398	89	9	GO:0061659
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	RLF ZNF10 ZNF132 ZNF320 KMT2D ZNF142 ZNF586 ZNF473 ZBED2 ZNF316 OSR1 ZNF221 RREB1 ZNF467 ZNF416 ZNF548	4.62e-04	1412	89	16	GO:0000981
GeneOntologyMolecularFunction	calcium ion binding	FBLN2 SPATA21 EFCAB12 EFEMP2 LRP2 SCUBE3 NID1 LTBP3 EDIL3 LTBP4 RASGRP2	4.89e-04	749	89	11	GO:0005509
GeneOntologyMolecularFunction	histone H3K4 monomethyltransferase activity	KMT2D KMT2A	5.41e-04	8	89	2	GO:0140945
GeneOntologyMolecularFunction	structural molecule activity	MFAP2 RELN FBLN2 VWF EFEMP2 NID1 TUBA4B EDIL3 ZP2 LTBP4 MUC4 MUC6	5.81e-04	891	89	12	GO:0005198
GeneOntologyMolecularFunction	acyltransferase activity	UBR1 RNF113B TRAF2 TRIM2 RNF113A CHFR RNF34 C10orf90 HERC2 UBE2E3 RNF208	6.50e-04	775	89	11	GO:0016746
GeneOntologyMolecularFunction	cytokine binding	TRAF2 ACKR3 SCUBE3 LTBP3 LTBP4	6.88e-04	157	89	5	GO:0019955
GeneOntologyMolecularFunction	histone H3K4 trimethyltransferase activity	KMT2D KMT2A	8.64e-04	10	89	2	GO:0140999
GeneOntologyMolecularFunction	histone H3 methyltransferase activity	KMT2D KMT2A KMT2E	9.93e-04	44	89	3	GO:0140938
GeneOntologyMolecularFunction	extracellular matrix constituent conferring elasticity	FBLN2 EFEMP2	1.26e-03	12	89	2	GO:0030023
GeneOntologyMolecularFunction	structural molecule activity conferring elasticity	FBLN2 EFEMP2	1.73e-03	14	89	2	GO:0097493
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF10 ZNF132 ZNF320 ZNF142 ZNF586 SLC2A4RG ZNF473 ZBED2 ZNF316 OSR1 ZNF221 RREB1 ZNF467 ZNF416 ZNF548	1.89e-03	1459	89	15	GO:0000977
GeneOntologyMolecularFunction	diacylglycerol binding	DGKD RASGRP2	2.26e-03	16	89	2	GO:0019992
GeneOntologyBiologicalProcess	snoRNA splicing	RNF113B RNF113A	1.76e-05	2	87	2	GO:0034247
GeneOntologyCellularComponent	collagen-containing extracellular matrix	MFAP2 RELN FBLN2 VWF EFEMP2 LOXL4 NID1 LTBP3 EDIL3 ZP2 USH2A LTBP4 MUC4	3.74e-07	530	89	13	GO:0062023
GeneOntologyCellularComponent	extracellular matrix	MFAP2 RELN FBLN2 VWF EFEMP2 LOXL4 NID1 LTBP3 EDIL3 ZP2 USH2A LTBP4 MUC4 MUC6	6.81e-07	656	89	14	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	MFAP2 RELN FBLN2 VWF EFEMP2 LOXL4 NID1 LTBP3 EDIL3 ZP2 USH2A LTBP4 MUC4 MUC6	7.06e-07	658	89	14	GO:0030312
GeneOntologyCellularComponent	microfibril	MFAP2 EFEMP2 LTBP4	2.07e-05	13	89	3	GO:0001527
Domain	cEGF	FBLN2 EFEMP2 LRP2 SCUBE3 NID1 LTBP3	1.96e-09	26	88	6	IPR026823
Domain	cEGF	FBLN2 EFEMP2 LRP2 SCUBE3 NID1 LTBP3	1.96e-09	26	88	6	PF12662
Domain	EGF_Ca-bd_CS	FBLN2 EFEMP2 LRP2 SCUBE3 NID1 LTBP3 EDIL3 LTBP4	1.80e-08	97	88	8	IPR018097
Domain	zf-C2H2	RLF ZNF10 ZNF132 ZNF320 ZNF142 ZNF586 SLC2A4RG ZNF473 ZNF592 ZNF316 OSR1 ZIM2 ZNF221 RREB1 ZNF467 ZNF416 ZNF548	2.06e-08	693	88	17	PF00096
Domain	EGF_CA	FBLN2 EFEMP2 LRP2 SCUBE3 NID1 LTBP3 EDIL3 LTBP4	2.12e-08	99	88	8	PS01187
Domain	ASX_HYDROXYL	FBLN2 EFEMP2 LRP2 SCUBE3 NID1 LTBP3 EDIL3 LTBP4	2.30e-08	100	88	8	PS00010
Domain	EGF_1	RELN FBLN2 EFEMP2 LRP2 SCUBE3 NID1 LTBP3 EDIL3 USH2A LTBP4 MUC4	3.14e-08	255	88	11	PS00022
Domain	EGF-type_Asp/Asn_hydroxyl_site	FBLN2 EFEMP2 LRP2 SCUBE3 NID1 LTBP3 EDIL3 LTBP4	3.64e-08	106	88	8	IPR000152
Domain	ZINC_FINGER_C2H2_2	RLF ZNF10 ZNF132 ZNF320 ZNF142 ZNF586 SLC2A4RG ZNF473 ZNF592 ZNF316 OSR1 ZIM2 ZNF221 RREB1 ZNF467 ZNF416 ZNF548	1.04e-07	775	88	17	PS50157
Domain	ZINC_FINGER_C2H2_1	RLF ZNF10 ZNF132 ZNF320 ZNF142 ZNF586 SLC2A4RG ZNF473 ZNF592 ZNF316 OSR1 ZIM2 ZNF221 RREB1 ZNF467 ZNF416 ZNF548	1.08e-07	777	88	17	PS00028
Domain	EGF_CA	FBLN2 EFEMP2 LRP2 SCUBE3 NID1 LTBP3 EDIL3 LTBP4	1.09e-07	122	88	8	SM00179
Domain	EGF-like_Ca-bd_dom	FBLN2 EFEMP2 LRP2 SCUBE3 NID1 LTBP3 EDIL3 LTBP4	1.24e-07	124	88	8	IPR001881
Domain	Znf_C2H2/integrase_DNA-bd	RLF ZNF10 ZNF132 ZNF320 ZNF142 ZNF586 SLC2A4RG ZNF473 ZNF316 OSR1 ZIM2 ZNF221 RREB1 ZNF467 ZNF416 ZNF548	1.33e-07	694	88	16	IPR013087
Domain	Znf_C2H2-like	RLF ZNF10 ZNF132 ZNF320 ZNF142 ZNF586 SLC2A4RG ZNF473 ZNF592 ZNF316 OSR1 ZIM2 ZNF221 RREB1 ZNF467 ZNF416 ZNF548	1.52e-07	796	88	17	IPR015880
Domain	EGF_3	RELN FBLN2 EFEMP2 LRP2 SCUBE3 NID1 LTBP3 EDIL3 LTBP4 MUC4	1.57e-07	235	88	10	PS50026
Domain	EGF	RELN FBLN2 EFEMP2 LRP2 SCUBE3 NID1 LTBP3 EDIL3 LTBP4 MUC4	1.57e-07	235	88	10	SM00181
Domain	EGF_CA	FBLN2 EFEMP2 LRP2 SCUBE3 NID1 LTBP3 LTBP4	1.61e-07	86	88	7	PF07645
Domain	-	UBR1 RNF113B TRAF2 KMT2D TRIM2 RNF113A CHFR RNF34 KMT2A KMT2E ZFYVE1 MLPH RNF208	1.76e-07	449	88	13	3.30.40.10
Domain	Znf_C2H2	RLF ZNF10 ZNF132 ZNF320 ZNF142 ZNF586 SLC2A4RG ZNF473 ZNF592 ZNF316 OSR1 ZIM2 ZNF221 RREB1 ZNF467 ZNF416 ZNF548	1.79e-07	805	88	17	IPR007087
Domain	ZnF_C2H2	RLF ZNF10 ZNF132 ZNF320 ZNF142 ZNF586 SLC2A4RG ZNF473 ZNF592 ZNF316 OSR1 ZIM2 ZNF221 RREB1 ZNF467 ZNF416 ZNF548	1.88e-07	808	88	17	SM00355
Domain	Znf_RING/FYVE/PHD	UBR1 RNF113B TRAF2 KMT2D TRIM2 RNF113A CHFR RNF34 KMT2A KMT2E ZFYVE1 MLPH RNF208	2.26e-07	459	88	13	IPR013083
Domain	EGF-like_dom	RELN FBLN2 EFEMP2 LRP2 SCUBE3 NID1 LTBP3 EDIL3 LTBP4 MUC4	2.69e-07	249	88	10	IPR000742
Domain	EGF-like_CS	RELN FBLN2 EFEMP2 LRP2 SCUBE3 NID1 LTBP3 EDIL3 LTBP4 MUC4	4.14e-07	261	88	10	IPR013032
Domain	EGF_2	RELN FBLN2 EFEMP2 LRP2 SCUBE3 NID1 LTBP3 EDIL3 LTBP4 MUC4	4.76e-07	265	88	10	PS01186
Domain	-	RLF ZNF10 ZNF132 ZNF320 ZNF142 ZNF586 ZNF473 ZNF316 OSR1 ZIM2 ZNF221 RREB1 ZNF467 ZNF416 ZNF548	5.93e-07	679	88	15	3.30.160.60
Domain	zf-C2H2_6	ZNF10 ZNF320 ZNF586 ZNF473 ZNF316 OSR1 RREB1 ZNF467 ZNF416 ZNF548	2.21e-06	314	88	10	PF13912
Domain	KRAB	ZNF10 ZNF132 ZNF320 ZNF586 ZNF473 ZNF316 ZIM2 ZNF221 ZNF416 ZNF548	7.07e-06	358	88	10	PS50805
Domain	KRAB	ZNF10 ZNF132 ZNF320 ZNF586 ZNF473 ZNF316 ZIM2 ZNF221 ZNF416 ZNF548	7.07e-06	358	88	10	PF01352
Domain	Growth_fac_rcpt_	FBLN2 EFEMP2 LRP2 SCUBE3 NID1 LTBP3 LTBP4	8.93e-06	156	88	7	IPR009030
Domain	KRAB	ZNF10 ZNF132 ZNF320 ZNF586 ZNF473 ZNF316 ZIM2 ZNF221 ZNF416 ZNF548	9.21e-06	369	88	10	SM00349
Domain	ZF_RING_1	UBR1 RNF113B TRAF2 KMT2D TRIM2 RNF113A CHFR RNF34 RNF208	9.31e-06	291	88	9	PS00518
Domain	KRAB	ZNF10 ZNF132 ZNF320 ZNF586 ZNF473 ZNF316 ZIM2 ZNF221 ZNF416 ZNF548	9.43e-06	370	88	10	IPR001909
Domain	ZF_RING_2	UBR1 RNF113B TRAF2 KMT2D TRIM2 RNF113A CHFR RNF34 RNF208	1.13e-05	298	88	9	PS50089
Domain	Znf_RING	UBR1 RNF113B TRAF2 KMT2D TRIM2 RNF113A CHFR RNF34 RNF208	2.29e-05	326	88	9	IPR001841
Domain	TIL_dom	VWF LRP2 MUC6	3.54e-05	14	88	3	IPR002919
Domain	VWD	VWF MUC4 MUC6	5.41e-05	16	88	3	SM00216
Domain	VWF_type-D	VWF MUC4 MUC6	5.41e-05	16	88	3	IPR001846
Domain	VWFD	VWF MUC4 MUC6	5.41e-05	16	88	3	PS51233
Domain	VWD	VWF MUC4 MUC6	5.41e-05	16	88	3	PF00094
Domain	Znf_FYVE_PHD	KMT2D RNF34 KMT2A KMT2E ZFYVE1 MLPH	6.84e-05	147	88	6	IPR011011
Domain	RING	RNF113B TRAF2 KMT2D TRIM2 RNF113A CHFR RNF34 RNF208	9.56e-05	305	88	8	SM00184
Domain	Znf_RING_CS	RNF113B TRAF2 TRIM2 RNF113A CHFR RNF208	1.21e-04	163	88	6	IPR017907
Domain	NIDO_dom	NID1 MUC4	2.17e-04	5	88	2	IPR003886
Domain	FYrich_C	KMT2D KMT2A	2.17e-04	5	88	2	IPR003889
Domain	FYrich_N	KMT2D KMT2A	2.17e-04	5	88	2	IPR003888
Domain	FYRC	KMT2D KMT2A	2.17e-04	5	88	2	SM00542
Domain	FYRN	KMT2D KMT2A	2.17e-04	5	88	2	SM00541
Domain	NIDO	NID1 MUC4	2.17e-04	5	88	2	SM00539
Domain	NIDO	NID1 MUC4	2.17e-04	5	88	2	PF06119
Domain	NIDO	NID1 MUC4	2.17e-04	5	88	2	PS51220
Domain	FYRN	KMT2D KMT2A	2.17e-04	5	88	2	PF05964
Domain	FYRC	KMT2D KMT2A	2.17e-04	5	88	2	PF05965
Domain	FYRC	KMT2D KMT2A	2.17e-04	5	88	2	PS51543
Domain	FYRN	KMT2D KMT2A	2.17e-04	5	88	2	PS51542
Domain	Mab-21-like_1/2	MAB21L2 MAB21L1	2.17e-04	5	88	2	IPR020950
Domain	EGF	LRP2 SCUBE3 NID1 EDIL3 MUC4	3.23e-04	126	88	5	PF00008
Domain	TB	LTBP3 LTBP4	4.54e-04	7	88	2	PF00683
Domain	-	LTBP3 LTBP4	6.03e-04	8	88	2	3.90.290.10
Domain	Znf_FYVE	RNF34 ZFYVE1 MLPH	7.57e-04	38	88	3	IPR000306
Domain	TB	LTBP3 LTBP4	7.73e-04	9	88	2	PS51364
Domain	TB_dom	LTBP3 LTBP4	7.73e-04	9	88	2	IPR017878
Domain	-	TRIM2 LRP2 NID1	8.17e-04	39	88	3	2.120.10.30
Domain	ZF_FYVE	RNF34 ZFYVE1 MLPH	8.80e-04	40	88	3	PS50178
Domain	SET	KMT2D KMT2A KMT2E	9.47e-04	41	88	3	PF00856
Domain	SET	KMT2D KMT2A KMT2E	1.33e-03	46	88	3	SM00317
Domain	6-blade_b-propeller_TolB-like	TRIM2 LRP2 NID1	1.33e-03	46	88	3	IPR011042
Domain	EGF_3	SCUBE3 NID1	1.40e-03	12	88	2	PF12947
Domain	TIL	VWF MUC6	1.40e-03	12	88	2	PF01826
Domain	EGF_dom	SCUBE3 NID1	1.40e-03	12	88	2	IPR024731
Domain	Mab-21_dom	MAB21L2 MAB21L1	1.40e-03	12	88	2	IPR024810
Domain	Mab-21	MAB21L2 MAB21L1	1.40e-03	12	88	2	PF03281
Domain	Mab-21	MAB21L2 MAB21L1	1.40e-03	12	88	2	SM01265
Domain	C8	VWF MUC6	1.40e-03	12	88	2	PF08742
Domain	Unchr_dom_Cys-rich	VWF MUC6	1.66e-03	13	88	2	IPR014853
Domain	C8	VWF MUC6	1.66e-03	13	88	2	SM00832
Domain	SET_dom	KMT2D KMT2A KMT2E	1.69e-03	50	88	3	IPR001214
Domain	SET	KMT2D KMT2A KMT2E	1.69e-03	50	88	3	PS50280
Domain	Ldl_recept_b	LRP2 NID1	1.93e-03	14	88	2	PF00058
Domain	LDLRB	LRP2 NID1	1.93e-03	14	88	2	PS51120
Domain	LY	LRP2 NID1	2.21e-03	15	88	2	SM00135
Domain	LDLR_classB_rpt	LRP2 NID1	2.21e-03	15	88	2	IPR000033
Domain	Post-SET_dom	KMT2D KMT2A	2.52e-03	16	88	2	IPR003616
Domain	PostSET	KMT2D KMT2A	2.52e-03	16	88	2	SM00508
Domain	POST_SET	KMT2D KMT2A	2.52e-03	16	88	2	PS50868
Domain	EGF_extracell	RELN LRP2 EDIL3	2.85e-03	60	88	3	IPR013111
Domain	EGF_2	RELN LRP2 EDIL3	2.85e-03	60	88	3	PF07974
Domain	VWC_out	VWF MUC6	3.56e-03	19	88	2	SM00215
Domain	zf-C3HC4	RNF113B TRAF2 TRIM2 RNF113A CHFR	4.07e-03	223	88	5	PF00097
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	MFAP2 FBLN2 EFEMP2 LOXL4 LTBP3 LTBP4	2.41e-08	39	66	6	MM14601
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	MFAP2 FBLN2 EFEMP2 LOXL4 LTBP3 LTBP4	5.13e-08	44	66	6	M26969
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	MFAP2 FBLN2 EFEMP2 LTBP3 LTBP4	3.52e-07	32	66	5	MM14854
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	MFAP2 FBLN2 EFEMP2 LTBP3 LTBP4	7.49e-07	37	66	5	M27134
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	MFAP2 FBLN2 VWF EFEMP2 SCUBE3 LOXL4 NID1 LTBP3 LTBP4	2.98e-06	258	66	9	MM14572
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	MFAP2 FBLN2 VWF EFEMP2 SCUBE3 LOXL4 NID1 LTBP3 LTBP4	1.01e-05	300	66	9	M610
Pubmed	Latent transforming growth factor beta-binding proteins and fibulins compete for fibrillin-1 and exhibit exquisite specificities in binding sites.	FBLN2 EFEMP2 LTBP4	3.22e-07	6	89	3	19349279
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	MFAP2 RELN FBLN2 VWF NID1 LTBP4 MUC4	3.53e-07	175	89	7	28071719
Pubmed	Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.	KMT2D KMT2A KMT2E	8.99e-07	8	89	3	23130995
Pubmed	Functional consequence of fibulin-4 missense mutations associated with vascular and skeletal abnormalities and cutis laxa.	EFEMP2 LTBP3 LTBP4	8.99e-07	8	89	3	27339457
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	FBLN2 VWF NID1 LTBP3 EDIL3 LTBP4	2.15e-06	146	89	6	27068509
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	MFAP2 FBLN2 VWF EFEMP2 NID1 LTBP4	4.68e-06	167	89	6	22159717
Pubmed	Control of lung development by latent TGF-β binding proteins.	LTBP3 LTBP4	6.48e-06	2	89	2	20945348
Pubmed	The Male Abnormal Gene Family 21 (Mab21) Members Regulate Eye Development.	MAB21L2 MAB21L1	6.48e-06	2	89	2	27558071
Pubmed	Genomic cloning and chromosomal localization of the mouse Mab21l2 locus.	MAB21L2 MAB21L1	6.48e-06	2	89	2	10516425
Pubmed	Set1 and MLL1/2 Target Distinct Sets of Functionally Different Genomic Loci In Vivo.	KMT2D KMT2A	6.48e-06	2	89	2	26711341
Pubmed	Mll2 is required for H3K4 trimethylation on bivalent promoters in embryonic stem cells, whereas Mll1 is redundant.	KMT2D KMT2A	6.48e-06	2	89	2	24423662
Pubmed	Depletion of Mab21l1 and Mab21l2 messages in mouse embryo arrests axial turning, and impairs notochord and neural tube differentiation.	MAB21L2 MAB21L1	6.48e-06	2	89	2	11857508
Pubmed	Altered expression of MLL methyltransferase family genes in breast cancer.	KMT2D KMT2E	6.48e-06	2	89	2	23754336
Pubmed	Immunohistochemical expression profiles of mucin antigens in salivary gland mucoepidermoid carcinoma: MUC4- and MUC6-negative expression predicts a shortened survival in the early postoperative phase.	MUC4 MUC6	6.48e-06	2	89	2	28649694
Pubmed	The role of Zfp467 in mediating the pro-osteogenic and anti-adipogenic effects on bone and bone marrow niche.	ZNF467 EDIL3	6.48e-06	2	89	2	33359894
Pubmed	Systematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networks.	TRIM2 RNF113A CHFR RNF34 RNF208	7.73e-06	105	89	5	22493164
Pubmed	Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.	TRAF2 VWF EFEMP2 LTBP3 LTBP4	1.36e-05	118	89	5	21078624
Pubmed	Aberrant expression of mucin core proteins and o-linked glycans associated with progression of pancreatic cancer.	MUC4 MUC6	1.94e-05	3	89	2	23446997
Pubmed	Secretory carcinoma of breast: pattern of MUC 2/MUC 4/MUC 6 expression.	MUC4 MUC6	1.94e-05	3	89	2	23305535
Pubmed	Function of Ltbp-4L and fibulin-4 in survival and elastogenesis in mice.	EFEMP2 LTBP4	1.94e-05	3	89	2	27585882
Pubmed	Pygo2 functions as a prognostic factor for glioma due to its up-regulation of H3K4me3 and promotion of MLL1/MLL2 complex recruitment.	KMT2D KMT2A	1.94e-05	3	89	2	26902498
Pubmed	Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.	KMT2D KMT2A	1.94e-05	3	89	2	23932714
Pubmed	MLL histone methylases regulate expression of HDLR-SR-B1 in presence of estrogen and control plasma cholesterol in vivo.	KMT2D KMT2A	1.94e-05	3	89	2	23192982
Pubmed	Comprehensive clinical and molecular analysis of 12 families with type 1 recessive cutis laxa.	EFEMP2 LTBP4	1.94e-05	3	89	2	22829427
Pubmed	Recurrent YAP1 and KMT2A Gene Rearrangements in a Subset of MUC4-negative Sclerosing Epithelioid Fibrosarcoma.	KMT2A MUC4	1.94e-05	3	89	2	31592798
Pubmed	Mice lacking the extracellular matrix protein MAGP1 display delayed thrombotic occlusion following vessel injury.	MFAP2 VWF	1.94e-05	3	89	2	18281502
Pubmed	Loss of enteric neuronal Ndrg4 promotes colorectal cancer via increased release of Nid1 and Fbln2.	FBLN2 NID1	1.94e-05	3	89	2	33890711
Pubmed	Modeling autosomal recessive cutis laxa type 1C in mice reveals distinct functions for Ltbp-4 isoforms.	EFEMP2 LTBP4	1.94e-05	3	89	2	25713297
Pubmed	Distinct pathways affected by menin versus MLL1/MLL2 in MLL-rearranged acute myeloid leukemia.	KMT2D KMT2A	1.94e-05	3	89	2	30315824
Pubmed	Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.	KMT2D KMT2A KMT2E	2.08e-05	21	89	3	27626377
Pubmed	Functional proteomics mapping of a human signaling pathway.	RLF UIMC1 KMT2D VWF ZNF592 NID1 LTBP3 DAAM1 HERC2	2.11e-05	591	89	9	15231748
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	RELN TRAF2 WAPL VWF ZNF473 ZNF592 EFEMP2 ADGRB3 LRP2 LTBP3 HERC2 EDIL3 WDR26	2.33e-05	1285	89	13	35914814
Pubmed	Structural basis for activity regulation of MLL family methyltransferases.	KMT2D KMT2A KMT2E	2.41e-05	22	89	3	26886794
Pubmed	Adult loss of Cacna1a in mice recapitulates childhood absence epilepsy by distinct thalamic bursting mechanisms.	CACNA1G EDIL3	3.87e-05	4	89	2	31800012
Pubmed	Carm1 regulates Pax7 transcriptional activity through MLL1/2 recruitment during asymmetric satellite stem cell divisions.	KMT2D KMT2A	3.87e-05	4	89	2	22863532
Pubmed	Latent transforming growth factor-beta (TGF-beta) binding proteins: orchestrators of TGF-beta availability.	LTBP3 LTBP4	3.87e-05	4	89	2	15611103
Pubmed	The collagen type XVIII endostatin domain is co-localized with perlecan in basement membranes in vivo.	FBLN2 NID1	3.87e-05	4	89	2	12588956
Pubmed	Human ubiquitin specific protease 31 is a deubiquitinating enzyme implicated in activation of nuclear factor-kappaB.	USP31 TRAF2	3.87e-05	4	89	2	16214042
Pubmed	KDM5A noncanonically binds antagonists MLL1/2 to mediate gene regulation and promotes epithelial to mesenchymal transition.	KMT2D KMT2A	3.87e-05	4	89	2	37722486
Pubmed	Forelimb contractures and abnormal tendon collagen fibrillogenesis in fibulin-4 null mice.	FBLN2 EFEMP2	3.87e-05	4	89	2	26711913
Pubmed	A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.	KMT2D KMT2A	3.87e-05	4	89	2	23129768
Pubmed	The MLL3/MLL4 branches of the COMPASS family function as major histone H3K4 monomethylases at enhancers.	KMT2D KMT2A	3.87e-05	4	89	2	24081332
Pubmed	The latent transforming growth factor beta binding protein (LTBP) family.	LTBP3 LTBP4	3.87e-05	4	89	2	11104663
Pubmed	Sequential deposition of latent TGF-beta binding proteins (LTBPs) during formation of the extracellular matrix in human lung fibroblasts.	LTBP3 LTBP4	3.87e-05	4	89	2	16157329
Pubmed	Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network.	RNF113B TRIM2 CHFR RNF34 UBE2E3	4.19e-05	149	89	5	19549727
Pubmed	Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.	MFAP2 FBLN2 VWF NID1 LTBP4	4.76e-05	153	89	5	25037231
Pubmed	Evolving Catalytic Properties of the MLL Family SET Domain.	KMT2D KMT2A	6.44e-05	5	89	2	26320581
Pubmed	Assessment of the association between genetic polymorphisms in transforming growth factor beta, and its binding protein (LTBP), and the presence, and expansion, of Abdominal Aortic Aneurysm.	LTBP3 LTBP4	6.44e-05	5	89	2	19897194
Pubmed	Target gene repression mediated by miRNAs miR-181c and miR-9 both of which are down-regulated by amyloid-β.	TRIM2 BTBD3	6.44e-05	5	89	2	21720722
Pubmed	A critical function of the pial basement membrane in cortical histogenesis.	RELN NID1	6.44e-05	5	89	2	12122064
Pubmed	MLL2, Not MLL1, Plays a Major Role in Sustaining MLL-Rearranged Acute Myeloid Leukemia.	KMT2D KMT2A	6.44e-05	5	89	2	28609655
Pubmed	Binding of mouse nidogen-2 to basement membrane components and cells and its expression in embryonic and adult tissues suggest complementary functions of the two nidogens.	FBLN2 NID1	6.44e-05	5	89	2	12243745
Pubmed	Mapping of binding sites for nidogens, fibulin-2, fibronectin and heparin to different IG modules of perlecan.	FBLN2 NID1	6.44e-05	5	89	2	11493006
Pubmed	RNA sensor LGP2 inhibits TRAF ubiquitin ligase to negatively regulate innate immune signaling.	TRAF2 DHX58	6.44e-05	5	89	2	29661858
Pubmed	Inflammation induces hemorrhage in thrombocytopenia.	VWF RASGRP2	6.44e-05	5	89	2	18256319
Pubmed	CXCR7 prevents excessive CXCL12-mediated downregulation of CXCR4 in migrating cortical interneurons.	RELN ACKR3	6.44e-05	5	89	2	24718993
Pubmed	MAB21L1 modulates gene expression and DNA metabolic processes in the lens placode.	MAB21L2 MAB21L1	6.44e-05	5	89	2	34779479
Pubmed	MUC1, MUC2, MUC4, MUC5AC and MUC6 expression in the progression of prostate cancer.	MUC4 MUC6	6.44e-05	5	89	2	16475027
Pubmed	Short arm region of laminin-5 gamma2 chain: structure, mechanism of processing and binding to heparin and proteins.	FBLN2 NID1	6.44e-05	5	89	2	11733994
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	WAPL ZNF592 ADGRB3 PAN2 AMBRA1 CACNA1G DAAM1 ZFYVE1	6.52e-05	529	89	8	14621295
Pubmed	Comprehensive proteomic characterization of stem cell-derived extracellular matrices.	MFAP2 FBLN2 EFEMP2 EDIL3	7.25e-05	86	89	4	28327460
Pubmed	An evolutionarily conserved nested gene pair - Mab21 and Lrba/Nbea in metazoan.	MAB21L2 MAB21L1	9.65e-05	6	89	2	19482073
Pubmed	Expression and function of CXCR7 in the mouse forebrain.	RELN ACKR3	9.65e-05	6	89	2	20681075
Pubmed	Cleavage of TFIIA by Taspase1 activates TRF2-specified mammalian male germ cell programs.	KMT2D KMT2A	9.65e-05	6	89	2	24176642
Pubmed	GRWD1-WDR5-MLL2 Epigenetic Complex Mediates H3K4me3 Mark and Is Essential for Kaposi's Sarcoma-Associated Herpesvirus-Induced Cellular Transformation.	KMT2D KMT2A	9.65e-05	6	89	2	34933446
Pubmed	Candidate gene isolation and comparative analysis of a commonly deleted segment of 7q22 implicated in myeloid malignancies.	RELN KMT2E	9.65e-05	6	89	2	11597142
Pubmed	MLL associates specifically with a subset of transcriptionally active target genes.	KMT2D KMT2A	9.65e-05	6	89	2	16199523
Pubmed	Tropoelastin binding to fibulins, nidogen-2 and other extracellular matrix proteins.	FBLN2 NID1	9.65e-05	6	89	2	10544250
Pubmed	Protein kinase C signaling dysfunction in von Willebrand disease (p.V1316M) type 2B platelets.	VWF RASGRP2	9.65e-05	6	89	2	29925524
Pubmed	Molecular evolution of the fibulins: implications on the functionality of the elastic fibulins.	FBLN2 EFEMP2	9.65e-05	6	89	2	20595023
Pubmed	WNK1 protein kinase regulates embryonic cardiovascular development through the OSR1 signaling cascade.	OSR1 EDIL3	9.65e-05	6	89	2	23386621
Pubmed	Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.	UBR1 TRAF2 CHFR HERC2	1.07e-04	95	89	4	29643511
Pubmed	The primitive endoderm segregates from the epiblast in β1 integrin-deficient early mouse embryos.	LRP2 EDIL3	1.35e-04	7	89	2	24277939
Pubmed	Clustered PHD domains in KMT2/MLL proteins are attracted by H3K4me3 and H3 acetylation-rich active promoters and enhancers.	KMT2D KMT2A	1.35e-04	7	89	2	36598580
Pubmed	A flexible, multilayered protein scaffold maintains the slit in between glomerular podocytes.	NID1 EDIL3	1.35e-04	7	89	2	27430022
Pubmed	Matrix Metalloproteinase-9 gene induction by a truncated oncogenic NF-kappaB2 protein involves the recruitment of MLL1 and MLL2 H3K4 histone methyltransferase complexes.	KMT2D KMT2A	1.35e-04	7	89	2	19219072
Pubmed	Specific sequence motif of 8-Cys repeats of TGF-beta binding proteins, LTBPs, creates a hydrophobic interaction surface for binding of small latent TGF-beta.	LTBP3 LTBP4	1.35e-04	7	89	2	10930463
Pubmed	Two murine and human homologs of mab-21, a cell fate determination gene involved in Caenorhabditis elegans neural development.	MAB21L2 MAB21L1	1.35e-04	7	89	2	10556287
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	TRAF2 FBLN2 EFEMP2 LRP2 CACNA1G MTERF4 LTBP4 UBE2E3	1.70e-04	608	89	8	16713569
Pubmed	Hepatitis C virus infection protein network.	FBLN2 VWF LTBP4	1.73e-04	42	89	3	18985028
Pubmed	Preferential expression of connexin37 and connexin40 in the endothelium of the portal veins during mouse liver development.	VWF NID1	1.79e-04	8	89	2	16505993
Pubmed	EMILIN proteins are novel extracellular constituents of the dentin-pulp complex.	FBLN2 NID1	1.79e-04	8	89	2	32948785
Pubmed	The leucine-rich repeat protein PRELP binds perlecan and collagens and may function as a basement membrane anchor.	FBLN2 NID1	1.79e-04	8	89	2	11847210
Pubmed	The mutational landscape of lethal castration-resistant prostate cancer.	KMT2D KMT2A	1.79e-04	8	89	2	22722839
Pubmed	The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.	KMT2D KMT2A	1.79e-04	8	89	2	22266653
Pubmed	Cdx2 determines the fate of postnatal intestinal endoderm.	EDIL3 MUC6	1.79e-04	8	89	2	22190642
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	UBR1 TRAF2 WAPL PAN2 HERC2	2.20e-04	212	89	5	33853758
Pubmed	Congenital Diaphragmatic Hernia Overview	KMT2D LRP2 LTBP4	2.27e-04	46	89	3	20301533
Pubmed	Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.	KMT2D KMT2A	2.30e-04	9	89	2	22665483
Pubmed	The SUMO-specific isopeptidase SENP3 regulates MLL1/MLL2 methyltransferase complexes and controls osteogenic differentiation.	KMT2D KMT2A	2.30e-04	9	89	2	24930734
Pubmed	LDL receptor-related protein as a component of the midkine receptor.	LRP2 NID1	2.30e-04	9	89	2	10772929
Pubmed	WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development.	KMT2D KMT2A	2.30e-04	9	89	2	15960974
Pubmed	Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression.	KMT2D KMT2A	2.30e-04	9	89	2	16951254
Pubmed	Physical Interactions and Functional Coordination between the Core Subunits of Set1/Mll Complexes and the Reprogramming Factors.	KMT2D KMT2A	2.30e-04	9	89	2	26691508
Pubmed	A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system.	RNF113B TRIM2 RNF113A UBE2E3	2.46e-04	118	89	4	19690564
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	RLF UIMC1 ZNF320 ZNF142 ZNF473 BMP2K ZNF316 LOXL4 SLFN5 KMT2E ZNF467	2.51e-04	1203	89	11	29180619
Pubmed	Functional consequences of cell type-restricted expression of laminin α5 in mouse placental labyrinth and kidney glomerular capillaries.	NID1 EDIL3	2.88e-04	10	89	2	22911783
Pubmed	ACKR3 Regulation of Neuronal Migration Requires ACKR3 Phosphorylation, but Not β-Arrestin.	RELN ACKR3	2.88e-04	10	89	2	30726732
Pubmed	Beta1-class integrins regulate the development of laminae and folia in the cerebral and cerebellar cortex.	RELN NID1	2.88e-04	10	89	2	11516395
Pubmed	Recombination suppression by heterozygous Robertsonian chromosomes in the mouse.	RELN MLPH	2.88e-04	10	89	2	8454207
Interaction	HOXA1 interactions	MFAP2 TRAF2 FBLN2 VWF EFEMP2 ZIM2 LTBP3 LTBP4 KRTAP10-9 RNF208	3.12e-06	356	87	10	int:HOXA1
Interaction	COL4A3 interactions	MFAP2 FBLN2 NID1 USH2A	8.15e-06	30	87	4	int:COL4A3
Interaction	UBE2D3 interactions	TRAF2 TRIM2 RNF113A CHFR RNF34 AMBRA1 HERC2 UBASH3B	3.07e-05	283	87	8	int:UBE2D3
Cytoband	12q24.33	ZNF10 CHFR LRCOL1	1.14e-04	48	89	3	12q24.33
Cytoband	15q13	UBR1 HERC2	1.33e-04	9	89	2	15q13
Cytoband	11q13.1	SNX32 EFEMP2 LTBP3	2.57e-04	63	89	3	11q13.1
Cytoband	2q37.3	ACKR3 MTERF4 MLPH	4.64e-04	77	89	3	2q37.3
Cytoband	19q13.4	ZNF132 ZIM2 ZNF416	5.01e-04	79	89	3	19q13.4
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF132 ZNF320 ZNF586 ZNF473 ZIM2 ZNF221 LTBP4 ZNF416 ZNF548	5.16e-04	1192	89	9	chr19q13
Cytoband	Ensembl 112 genes in cytogenetic band chr2q37	ACKR3 DGKD MTERF4 MLPH	1.01e-03	226	89	4	chr2q37
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	RLF ZNF10 ZNF132 ZNF320 ZNF142 ZNF586 ZNF473 ZNF592 ZNF316 OSR1 ZIM2 ZNF221 RREB1 ZNF467 ZNF416 ZNF548	8.68e-09	718	69	16	28
GeneFamily	Ring finger proteins	RNF113B TRAF2 TRIM2 RNF113A CHFR RNF34 RNF208	8.42e-05	275	69	7	58
GeneFamily	Latent transforming growth factor beta binding proteins	LTBP3 LTBP4	8.57e-05	4	69	2	628
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	KMT2D KMT2A KMT2E	2.92e-04	34	69	3	487
GeneFamily	Fibulins	FBLN2 EFEMP2	3.96e-04	8	69	2	556
GeneFamily	CD molecules\|Mucins	MUC4 MUC6	2.88e-03	21	69	2	648
GeneFamily	PHD finger proteins	KMT2D KMT2A KMT2E	4.93e-03	90	69	3	88
Coexpression	NABA_ECM_GLYCOPROTEINS	MFAP2 RELN FBLN2 VWF EFEMP2 NID1 LTBP3 EDIL3 ZP2 USH2A LTBP4	6.78e-11	196	89	11	M3008
Coexpression	NABA_ECM_GLYCOPROTEINS	MFAP2 RELN FBLN2 VWF EFEMP2 NID1 LTBP3 EDIL3 ZP2 LTBP4	1.03e-09	191	89	10	MM17059
Coexpression	NABA_CORE_MATRISOME	MFAP2 RELN FBLN2 VWF EFEMP2 NID1 LTBP3 EDIL3 ZP2 USH2A LTBP4	2.46e-09	275	89	11	M5884
Coexpression	NABA_CORE_MATRISOME	MFAP2 RELN FBLN2 VWF EFEMP2 NID1 LTBP3 EDIL3 ZP2 LTBP4	2.83e-08	270	89	10	MM17057
Coexpression	NABA_MATRISOME	SEMA6B MFAP2 RELN FBLN2 VWF EFEMP2 SCUBE3 LOXL4 NID1 LTBP3 EDIL3 ZP2 USH2A LTBP4 MUC4 MUC6	3.26e-07	1026	89	16	M5889
Coexpression	NABA_MATRISOME	SEMA6B MFAP2 RELN FBLN2 VWF EFEMP2 SCUBE3 LOXL4 NID1 LTBP3 EDIL3 ZP2 LTBP4 MUC4 MUC6	1.43e-06	1008	89	15	MM17056
Coexpression	GSE13411_NAIVE_VS_IGM_MEMORY_BCELL_UP	ADCY10 ZNF473 CHFR DGKD MAB21L2 USH2A RASGRP2	4.82e-06	196	89	7	M3239
Coexpression	CUI_DEVELOPING_HEART_C3_FIBROBLAST_LIKE_CELL	MFAP2 FBLN2 EFEMP2 NID1 LTBP4	5.01e-05	117	89	5	M39300
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MFAP2 FBLN2 VWF ACKR3 PAN2 SLFN5 LTBP4	4.95e-08	169	89	7	58136b8a0bf2dab45c91a053ef7225ea49ccb871
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MFAP2 FBLN2 VWF ACKR3 PAN2 SLFN5 LTBP4	4.95e-08	169	89	7	04c6ed38e1d1befba5ef5f37a3c1e045a0b163d6
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MFAP2 RELN FBLN2 KCND1 ACKR3 NID1 LTBP4	6.80e-08	177	89	7	227d4f423b00be2e0c5797e2c5275d342e69a0f4
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MFAP2 RELN FBLN2 KCND1 ACKR3 NID1 LTBP4	6.80e-08	177	89	7	66ffa279147961080c104242a08b176e301d80e3
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MFAP2 RELN FBLN2 KCND1 ACKR3 NID1 LTBP4	6.80e-08	177	89	7	0cbf54608d2ba0a0500af142f2029fe5e118c3c2
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MFAP2 EFEMP2 NID1 MAB21L2 EDIL3 LTBP4 UBE2E3	1.51e-07	199	89	7	3d8c76e3d05acf72a35ca755b51579fc3ae63562
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACKR3 EFEMP2 SCUBE3 LOXL4 NID1 EDIL3 LTBP4	1.51e-07	199	89	7	137ff58897e6ada8a5a70205f66fe9110795506b
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MFAP2 FBLN2 ACKR3 EFEMP2 OSR1 NID1 LTBP4	1.56e-07	200	89	7	3e6730c9ed7003a4acf501f699a4965a7a50f946
ToppCell	Biopsy_Other_PF-Mesenchymal\|Biopsy_Other_PF / Sample group, Lineage and Cell type	MFAP2 FBLN2 EFEMP2 OSR1 NID1 EDIL3 LTBP4	1.56e-07	200	89	7	d6fcdd48858b53b5a8d18ae14b2dc4d9af41b070
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_A2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TRAF2 BMP2K TMEM63B AMBRA1 RREB1 ZFYVE1	1.41e-06	175	89	6	334fad1a147de6c007cec5089c02c35cf3220f1b
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN2 OSR1 LRP2 LOXL4 NID1 LTBP4	2.08e-06	187	89	6	4e553721fa5598cb211f44e3226280b7e6885484
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN2 OSR1 LRP2 LOXL4 NID1 LTBP4	2.08e-06	187	89	6	d36e7fc6125e7a4310499365022d38f34b757a73
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN2 OSR1 LRP2 LOXL4 NID1 LTBP4	2.08e-06	187	89	6	827eae63fabf6892a82ce7779b5f395958d3d628
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MFAP2 FBLN2 ACKR3 OSR1 NID1 LTBP4	2.14e-06	188	89	6	e18065bbc26d6f3774fd1f478fb41d8fb555fa26
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-chondrocyte\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	MFAP2 ACKR3 ZIM2 SCUBE3 MAB21L2 EDIL3	2.14e-06	188	89	6	c9270517e6940e9793586f67f02431210552f278
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MFAP2 FBLN2 ACKR3 OSR1 NID1 LTBP4	2.21e-06	189	89	6	d531399749409d614adca13d181830c6e3287508
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MFAP2 FBLN2 EFEMP2 OSR1 NID1 LTBP4	2.35e-06	191	89	6	4e4488380379ed29d7898bae4e24221e7c67eb9d
ToppCell	droplet-Fat-Mat-18m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN2 OSR1 NID1 LTBP3 MAB21L2 LTBP4	2.49e-06	193	89	6	ebd090d7801480b3cee45caac3d30cc991836769
ToppCell	droplet-Fat-Mat-18m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN2 OSR1 NID1 LTBP3 MAB21L2 LTBP4	2.49e-06	193	89	6	22c58032e58730715224d7934968ce92d150b0e8
ToppCell	droplet-Fat-Scat-18m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 FBLN2 EFEMP2 OSR1 LOXL4 NID1	2.49e-06	193	89	6	316ebdf15f75d88c348f909b643fcd315364ca84
ToppCell	droplet-Fat-Scat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 FBLN2 EFEMP2 OSR1 LOXL4 NID1	2.49e-06	193	89	6	1afdd3f7d703f4204a2cbfe40e135ac7b09213f7
ToppCell	facs-MAT-Fat-24m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 FBLN2 EFEMP2 OSR1 NID1 LTBP4	2.49e-06	193	89	6	733f557bdc80293b40ccdf560f1675793df932d6
ToppCell	facs-MAT-Fat-24m-Mesenchymal\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 FBLN2 EFEMP2 OSR1 NID1 LTBP4	2.49e-06	193	89	6	eb3c46b6fb06dc8708dc3032189b47ed93ee2357
ToppCell	droplet-Fat-Scat-18m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 FBLN2 EFEMP2 OSR1 LOXL4 NID1	2.49e-06	193	89	6	8dc6db335678f3a5cfd36026ad811fed8d9cb4bc
ToppCell	droplet-Fat-Mat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN2 OSR1 NID1 LTBP3 MAB21L2 LTBP4	2.49e-06	193	89	6	573ad2f848bede1fe20c7b4b352a9242ec294725
ToppCell	facs-MAT-Fat-24m-Mesenchymal-mesenchymal_progenitor\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 FBLN2 EFEMP2 OSR1 NID1 LTBP4	2.49e-06	193	89	6	b45cd02081f97904eaea2d013e1fa980505d060b
ToppCell	facs-MAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 FBLN2 EFEMP2 OSR1 NID1 LTBP4	2.57e-06	194	89	6	f906b090f67df4cfe3498cdbb52cc0efa08e06cc
ToppCell	facs-MAT-Fat-18m-Mesenchymal\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 FBLN2 EFEMP2 OSR1 NID1 LTBP4	2.57e-06	194	89	6	944cdb0403d80a10a2eea2a3516a9343dbccc32c
ToppCell	facs-GAT-Fat-18m-Mesenchymal-mesenchymal_progenitor\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 FBLN2 EFEMP2 OSR1 NID1 LTBP4	2.57e-06	194	89	6	9709dc95fb6982b6a0467b507845d5bc17252e3e
ToppCell	facs-GAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 FBLN2 EFEMP2 OSR1 NID1 LTBP4	2.57e-06	194	89	6	93b7a9065430740ec31fce4e8c14ffccb498591d
ToppCell	facs-GAT-Fat-18m-Mesenchymal\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 FBLN2 EFEMP2 OSR1 NID1 LTBP4	2.57e-06	194	89	6	0d2e65b44e3f143971c2fd24c4552f042b049cfa
ToppCell	facs-MAT-Fat-18m-Mesenchymal-mesenchymal_progenitor\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 FBLN2 EFEMP2 OSR1 NID1 LTBP4	2.57e-06	194	89	6	85081d255fcc1e9854c0073321dd9f0feaa48866
ToppCell	facs-GAT-Fat-3m-Mesenchymal-mesenchymal_progenitor\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 ACKR3 EFEMP2 NID1 LTBP3 LTBP4	2.64e-06	195	89	6	69a29d03e664b72f32d41876510c62345c3aed31
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MFAP2 FBLN2 EFEMP2 OSR1 NID1 LTBP4	2.64e-06	195	89	6	1236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCell	facs-GAT-Fat-3m-Mesenchymal\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 ACKR3 EFEMP2 NID1 LTBP3 LTBP4	2.64e-06	195	89	6	1cffae2b08dbfa1c633ce24023e89b66d28b5431
ToppCell	facs-GAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 ACKR3 EFEMP2 NID1 LTBP3 LTBP4	2.64e-06	195	89	6	9cef6f18664518060af7c192310dddce6d70345a
ToppCell	facs-SCAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 FBLN2 ACKR3 EFEMP2 OSR1 NID1	2.72e-06	196	89	6	65f2f51e17f1869f3468813127b96d3048d8ad41
ToppCell	facs-SCAT-Fat-18m-Mesenchymal-mesenchymal_progenitor\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 FBLN2 ACKR3 EFEMP2 OSR1 NID1	2.72e-06	196	89	6	e4ed897900a6472738bc6be2fb4817192727225d
ToppCell	facs-SCAT-Fat-18m-Mesenchymal\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 FBLN2 ACKR3 EFEMP2 OSR1 NID1	2.72e-06	196	89	6	2cd83176f2e8a9e6fa3c08cb33928a61e5fc43b6
ToppCell	facs-Heart-LA-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 FBLN2 ACKR3 OSR1 NID1 LTBP4	2.72e-06	196	89	6	ad1838dabd043cb140260843e3527d8c7d58850e
ToppCell	Control-Stromal-Fibroblast\|Control / Disease state, Lineage and Cell class	MFAP2 FBLN2 EFEMP2 OSR1 NID1 LTBP4	2.72e-06	196	89	6	7ca94477498a84cafcdd9933ee92a6cbde76c70e
ToppCell	facs-Heart-LA-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 FBLN2 ACKR3 OSR1 NID1 LTBP4	2.72e-06	196	89	6	cbc15c0769016fe9972445169029bd8d14a7e6ef
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MFAP2 EFEMP2 NID1 MAB21L2 LTBP4 UBE2E3	2.81e-06	197	89	6	398a66c06df63567b176ab2cc85e27837e94d0d9
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACKR3 SCUBE3 NID1 EDIL3 LTBP4 MUC4	2.81e-06	197	89	6	1da8ba5bbab232add6e43ad78b15c2339d0c2bc3
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MFAP2 EFEMP2 NID1 EDIL3 LTBP4 UBE2E3	2.81e-06	197	89	6	236a40eb6c08e1d179cf0fb5450b032975c5f6b6
ToppCell	facs-Heart-LA-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 FBLN2 ACKR3 OSR1 NID1 LTBP4	2.81e-06	197	89	6	2a91738cb6d7588869dd00deeea0cbbc2d6aa34d
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MFAP2 SCUBE3 LOXL4 NID1 EDIL3 LTBP4	2.89e-06	198	89	6	09be07ebfc3e49c3858e9b74605b69cf4fc28b56
ToppCell	Control-Stromal\|Control / Disease state, Lineage and Cell class	MFAP2 FBLN2 EFEMP2 OSR1 NID1 LTBP4	2.89e-06	198	89	6	ae726b6b7f0a4107899be4d32ac256ffa0bd8d59
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MFAP2 EFEMP2 NID1 EDIL3 LTBP4 UBE2E3	2.89e-06	198	89	6	75d104eead681f6bf47c4dd24913cc768c9a1717
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACKR3 EFEMP2 SCUBE3 NID1 EDIL3 LTBP4	2.89e-06	198	89	6	4a4566f86c9365a41b4cfd1609eac09bd73b3f34
ToppCell	IPF-Stromal\|IPF / Disease state, Lineage and Cell class	MFAP2 FBLN2 EFEMP2 OSR1 NID1 LTBP4	2.89e-06	198	89	6	ece914c32c9b123b779aa9624b92e6230763a20e
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MFAP2 EFEMP2 NID1 MAB21L2 EDIL3 LTBP4	2.97e-06	199	89	6	34199597371a20d9f1dea9ad59edfb615b14c4f6
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MFAP2 FBLN2 EFEMP2 OSR1 NID1 LTBP4	2.97e-06	199	89	6	a538da095ba996ee96e263442cf5b6ba9178f3d4
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MFAP2 FBLN2 EFEMP2 OSR1 NID1 LTBP4	2.97e-06	199	89	6	4032f03a4165f5f2a90ef1d8315cc743ce9075bb
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MFAP2 EFEMP2 LOXL4 NID1 EDIL3 LTBP4	2.97e-06	199	89	6	e78f661b40da34768469549b6e755d330be6bbd8
ToppCell	Biopsy_IPF-Mesenchymal-PLIN2+_Fibroblasts\|Biopsy_IPF / Sample group, Lineage and Cell type	MFAP2 FBLN2 EFEMP2 OSR1 NID1 LTBP4	3.06e-06	200	89	6	2c5626ea8fb4b702d4560117e53edf6cfcf1971e
ToppCell	Bronchial-10x5prime-Stromal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MFAP2 FBLN2 EFEMP2 OSR1 NID1 LTBP4	3.06e-06	200	89	6	5ea12e17f50fefbf5534e487af3392b2fa2d13ad
ToppCell	Parenchymal-10x5prime-Stromal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MFAP2 FBLN2 EFEMP2 OSR1 NID1 LTBP4	3.06e-06	200	89	6	2e525c0d9684e7a2275edb04e1addb6fc6a872e5
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MFAP2 EFEMP2 NID1 MAB21L2 LTBP4 UBE2E3	3.06e-06	200	89	6	a603e8a999612d523bbce9d0feca9296d4a24c97
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_adventitial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MFAP2 FBLN2 EFEMP2 OSR1 NID1 LTBP4	3.06e-06	200	89	6	b04831708fa20471a127b87e8db3728b6e729ce8
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MFAP2 FBLN2 EFEMP2 OSR1 NID1 LTBP4	3.06e-06	200	89	6	6316c288022719b9e6c4332c5cb9041e1188d0e8
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-2,_SCARA5\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	MFAP2 FBLN2 EFEMP2 OSR1 NID1 LTBP4	3.06e-06	200	89	6	ef30f9b68bfdb8d947ed399603e4dd0d5ff0144d
ToppCell	Biopsy_IPF-Mesenchymal\|Biopsy_IPF / Sample group, Lineage and Cell type	MFAP2 FBLN2 EFEMP2 OSR1 NID1 LTBP4	3.06e-06	200	89	6	bb605b373caf3f873dc1b87d712704568e0d6040
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MFAP2 FBLN2 EFEMP2 OSR1 NID1 LTBP4	3.06e-06	200	89	6	b28bfe6eb96b4db9cb27f0fc8fc39259c125f05e
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MFAP2 FBLN2 EFEMP2 OSR1 NID1 LTBP4	3.06e-06	200	89	6	f6cf98aad53aa8b3fa02cf874d6f7cd75530a213
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	MFAP2 FBLN2 EFEMP2 OSR1 NID1 LTBP4	3.06e-06	200	89	6	87953ea65ff2a01485e13dd49d993ae6ae679cbf
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Tcf7l2_(Substantia_Innominata_(SI))\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MAB21L2 ZP2 MUC4 MAB21L1	5.22e-06	57	89	4	eab63d89e2100bb94fb026f700c2f82d657f92c1
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Tcf7l2_(Substantia_Innominata_(SI))-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MAB21L2 ZP2 MUC4 MAB21L1	5.22e-06	57	89	4	2dc04513910af16d2cd84b3ae5b8d4c831124c68
ToppCell	343B-Epithelial_cells-Epithelial-H_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MFAP2 RELN EFEMP2 LOXL4 UBASH3B	1.80e-05	161	89	5	da9eecf919866a9c579d7a707a996cf335213134
ToppCell	343B-Epithelial_cells-Epithelial-H_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MFAP2 RELN EFEMP2 LOXL4 UBASH3B	1.80e-05	161	89	5	d431625c32f59a6b552191f3adc5198bd16ad5cf
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEMA6B FBLN2 VWF ACKR3 LTBP4	1.80e-05	161	89	5	f4f5d6eaa32169de699c8ff8e8ae35179c8e25c0
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RELN FBLN2 ADGRB3 C10orf90 LTBP4	1.85e-05	162	89	5	d28b2ea1d2c8f3c6a107991573471b6d0c49c4ae
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RELN FBLN2 ADGRB3 C10orf90 LTBP4	1.85e-05	162	89	5	5bbd7130d4dad9035e73a439dda568195c136f31
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RELN FBLN2 ADGRB3 C10orf90 LTBP4	1.85e-05	162	89	5	eed223e61c8162a2fe004ab4e09de5e037be7553
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Neural\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RELN FBLN2 ADGRB3 C10orf90 LTBP4	1.85e-05	162	89	5	e35ddce830e20ebeac1a2c405293fc4a5323dd4a
ToppCell	PND03-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGAP6 TMEM151B DGKD UBASH3B RASGRP2	2.47e-05	172	89	5	e39ea2f4edbf36ebf9604fa6f9349081859c596c
ToppCell	PND03-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGAP6 TMEM151B DGKD UBASH3B RASGRP2	2.47e-05	172	89	5	875ea290840e835952623b905eb610f3c71456d2
ToppCell	PND03-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGAP6 TMEM151B DGKD UBASH3B RASGRP2	2.47e-05	172	89	5	bcc50bed47465daa953ba91f17d1ee4c947ab461
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF132 MFAP2 TRAF2 EFCAB12 OSR1	2.54e-05	173	89	5	9f892d756d05e573af018db64edb130ff187ad47
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MFAP2 FBLN2 VWF ACKR3 LOXL4	2.68e-05	175	89	5	2e54961846c65b185d9bd6e305dd81205579d890
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MFAP2 FBLN2 VWF ACKR3 LOXL4	2.68e-05	175	89	5	efa6a05f7417d46141b6e635f258c126b7a03aa1
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_A2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	BMP2K TMEM63B AMBRA1 RREB1 ZFYVE1	2.68e-05	175	89	5	da191dfb8a7f976a632a3a0b923942ab54f5c8c1
ToppCell	LA-01._Fibroblast_I\|LA / Chamber and Cluster_Paper	FBLN2 ACKR3 ADGRB3 NID1 LTBP4	2.99e-05	179	89	5	dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEMA6B FBLN2 VWF ACKR3 NID1	3.07e-05	180	89	5	40d4838a0ccb10d5e49266bc8a0037d27b75ccc2
ToppCell	Mesenchymal_cells-Stromal_fibro.\|Mesenchymal_cells / Lineage and Cell class	RELN FBLN2 UBASH3B LTBP4 RASGRP2	3.15e-05	181	89	5	f8d914fdc06aaa75a4dc9158daf574ca28fa5432
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1-41\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZCCHC4 FBLN2 OSR1 NID1 LTBP4	3.32e-05	183	89	5	07ca2786e62eca9feecf5e54a11864a960f7641a
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MFAP2 FBLN2 OSR1 NID1 LTBP4	3.49e-05	185	89	5	c85bba1210f1d389add3e40be9b96abac40cf8c1
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.4.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MFAP2 FBLN2 ACKR3 OSR1 LTBP4	3.59e-05	186	89	5	07d94d5d1c2fe7bb909a07ca81058a0eabc65c60
ToppCell	LA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	FBLN2 ACKR3 ADGRB3 NID1 LTBP4	3.68e-05	187	89	5	4ea486991f66c29728d127171a07b81404ec0b78
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBLN2 ACKR3 OSR1 NID1 LTBP4	3.77e-05	188	89	5	6c6486cae9a8f2f8200598cb4bfd3fd513eb28a3
ToppCell	Endothelial-Endothelial-E\|Endothelial / shred on cell class and cell subclass (v4)	FBLN2 VWF ACKR3 LTBP3 LTBP4	3.77e-05	188	89	5	2777eb7689b271c199021fe7d9db88ccebff14de
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN2 OSR1 LOXL4 NID1 LTBP4	3.87e-05	189	89	5	f0a2d4ef9896d764971ebbc6952510c128bb76e8
ToppCell	facs-BAT-Fat-18m-Mesenchymal\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 FBLN2 EFEMP2 OSR1 NID1	3.87e-05	189	89	5	bba28f57a0708515fdd5acd9592dbbe4a4f57116
ToppCell	facs-BAT-Fat-18m-Mesenchymal-mesenchymal_progenitor\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 FBLN2 EFEMP2 OSR1 NID1	3.87e-05	189	89	5	cf293b23a4c0e8a0c9f09115b1d53d9b11de72e2
ToppCell	wk_15-18-Mesenchymal-Fibroblast-Airway_fibro\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	FBLN2 SLC2A4RG EFEMP2 LTBP4 MAB21L1	3.87e-05	189	89	5	4f9608b84d135268a17455661870c46ae8554a24
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 FBLN2 ACKR3 EFEMP2 NID1	3.87e-05	189	89	5	bc54ffd7bd1627a36747a80ce5139e4a69928400
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN2 OSR1 LOXL4 NID1 LTBP4	3.87e-05	189	89	5	378f26f751ab4b470948c35dd8347de72dd12ff7
ToppCell	facs-Diaphragm-Limb_Muscle-18m-Mesenchymal-mesenchymal_stem_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 FBLN2 EFEMP2 OSR1 NID1	3.87e-05	189	89	5	dde037322c8caec0c04c5be1c1b59a167824ad9f
ToppCell	facs-BAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 FBLN2 EFEMP2 OSR1 NID1	3.87e-05	189	89	5	87323e86a5b5d159920a07e6bd7ef5e3438cd085
ToppCell	droplet-Pancreas-PANCREAS-30m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN2 VWF ACKR3 SLFN5 LTBP4	3.97e-05	190	89	5	9d5242759546be0089981ef1877e4ed5f81face5
Disease	cutis laxa (implicated_via_orthology)	EFEMP2 LTBP4	2.34e-05	3	83	2	DOID:3144 (implicated_via_orthology)
Disease	severe acute respiratory syndrome, COVID-19	ZCCHC4 ARHGAP6 RELN C10orf90 LTBP3 SLFN5 ZFYVE1 EDIL3	3.81e-05	447	83	8	EFO_0000694, MONDO_0100096
Disease	mucinous adenocarcinoma (is_marker_for)	MUC4 MUC6	7.77e-05	5	83	2	DOID:3030 (is_marker_for)
Disease	Cutis Laxa	EFEMP2 LTBP4	1.16e-04	6	83	2	C0010495
Disease	multiple system atrophy	USP31 LOXL4 RREB1	1.97e-04	40	83	3	EFO_1001050
Disease	Intellectual Disability	ZNF142 RNF113A LRP2 CACNA1G KMT2E WDR26 MAB21L1	2.69e-04	447	83	7	C3714756
Disease	Mitral valve prolapse, response to surgery	ZNF592 LTBP3	5.07e-04	12	83	2	EFO_0009951, HP_0001634
Disease	Proteinuria	VWF LRP2	8.02e-04	15	83	2	HP_0000093
Disease	congenital heart disease (implicated_via_orthology)	KMT2D LRP2 KMT2A	9.84e-04	69	83	3	DOID:1682 (implicated_via_orthology)
Disease	Myeloid Leukemia	KMT2A KMT2E	1.16e-03	18	83	2	C0023470
Disease	Leukemia, Monocytic, Chronic	KMT2A KMT2E	1.16e-03	18	83	2	C0023466
Disease	bipolar disorder (is_marker_for)	RELN VWF	1.30e-03	19	83	2	DOID:3312 (is_marker_for)
Disease	hypertrophic cardiomyopathy	ZNF592 AMBRA1 MUC6	2.25e-03	92	83	3	EFO_0000538
Disease	Degenerative polyarthritis	TRIM2 LTBP3 EDIL3	2.32e-03	93	83	3	C0029408
Disease	Osteoarthrosis Deformans	TRIM2 LTBP3 EDIL3	2.32e-03	93	83	3	C0086743

Protein segments in the cluster

Peptide	Gene	Start	Entry
RESRVCNNTALCPVH	ADGRB3	331	O60242
QVTPLHSGTYQCCAR	CD160	101	O95971
VPQRCHRFQSCAYRS	BTBD3	371	Q9Y2F9
NPNRHYQSLCRLSRC	ADCY10	1331	Q96PN6
RQRVSYPTAECCQHL	AMBRA1	291	Q9C0C7
PDNSRYSRNIHCLIR	BMP2K	281	Q9NSY1
IQYTEQCHLVRCGNR	EFCAB12	351	Q6NXP0
HSQCCIQLREYSPFR	LRCOL1	131	A6NCL2
CALYQQRRPHVGCAT	MUC4	4661	Q99102
ARCSCCRPLHSYEQQ	MUC6	2391	Q6W4X9
YFLEPVRCLIQNHLC	PAN2	536	Q504Q3
NFYRTGRLHCPRQEC	KCND1	96	Q9NSA2
RPLSQLYCAHEENCL	LOXL4	551	Q96JB6
FQESNSLRPVACRHC	RASGRP2	501	Q7LDG7
QIERYCRQCHLTTPI	HERC2	1411	O95714
CQRNPLICARGYHAS	FBLN2	836	P98095
LHNCDIPQRAQCIYT	NID1	766	P14543
RQHIPDTYLCERCQP	KMT2E	151	Q8IZD2
PNRFRCDNNRCIYSH	LRP2	3886	P98164
ALQHFRTTPRCYVCD	RNF113A	286	O15541
RPYTCDICHKAFRRQ	OSR1	201	Q8TAX0
VRDCLPTNVECSRYH	RELN	2411	P78509
IYRQVPRLVDSCCQH	ARHGAP6	406	O43182
CCFRNNDHPEITYRL	DAAM1	16	Q9Y4D1
AQYVRLYPQVCRRHC	EDIL3	291	O43854
VVCRQCPEYRRQAAQ	CHFR	426	Q96EP1
ICSRICVCGYPRQHV	FAM126A	206	Q9BYI3
VQDAYTLRCCPQVHG	HAL	391	P42357
CYSVEAQSCQRRPTS	CACNA1G	2246	O43497
NCTVLEARPCYNVAR	TMEM63B	266	Q5T3F8
SQQPCKQYNLCHRRS	DHX58	211	Q96C10
VHCCVNPVLYSFINR	ACKR3	306	P25106
QLISCLQCRRCPHYF	MAB21L2	306	Q9Y586
RSHPQHRYCVDVNEC	LTBP3	606	Q9NS15
CSHPRLDRQATYTEC	LTBP4	1361	Q8N2S1
HARPTYCNVCREALS	DGKD	171	Q16760
SVAYTCVNCTERHPA	KMT2A	1616	Q03164
NHSCEPNCYSRVINI	KMT2A	3906	Q03164
SRQPSYCRQASCVSL	KRTAP10-9	256	P60411
RYCQHRCVNLPGSFR	EFEMP2	171	O95967
HIDAICQNTPRSYKC	SCUBE3	41	Q8IX30
ETHCARCLQPYQLLV	MLPH	61	Q9BV36
RLYSIHRPCKQCLNE	MFAP2	106	P55001
NRCVAICNPFHYVTV	OR1L3	121	Q8NH93
GLRCNQCEPHRYNLT	USH2A	876	O75445
VRRQPSNHYALDQCT	SPATA21	416	Q7Z572
VAPYRRSCEHCQRAV	TMEM151B	426	Q8IW70
QLISCLQCRRCPHYF	MAB21L1	306	Q13394
LEHFRATPRCYICDQ	RNF113B	281	Q8IZP6
SCVRSNNYVQEPECR	MTERF4	56	Q7Z6M4
ICHCNLDIERPTYTN	TUBA4B	151	Q9H853
CQYVTSCHPKRSERR	ANGEL1	491	Q9UNK9
CVHLRVSQQCPDSIY	C10orf90	251	Q96M02
LRRPFQAQCGHRYCS	TRAF2	41	Q12933
LISRPTCNCIYNQLH	PRSS53	181	Q2L4Q9
RCVVRVPVARCQQYS	SEMA6B	516	Q9H3T3
QRVHTQERPYECIQC	ZNF132	646	P52740
QRVHTRERPYECSEC	ZNF586	281	Q9NXT0
HPNQYATCRLCGRQV	ZBED2	71	Q9BTP6
QRVHTGERPYTCNEC	ZNF320	376	A2RRD8
YRQCVSPCARTCQSL	VWF	301	P04275
QHRYSPFQCHICQRS	RLF	1166	Q13129
LECPTCGHSYNVTQR	RNF208	141	Q9H0X6
QSCHSDRVYQGCLTP	SLC2A4RG	311	Q9NR83
CPICRQYVVRAVHVF	RNF34	356	Q969K3
RNSYTNCLQKITCPH	RREB1	1236	Q92766
TRIYHCNINSQGVIC	UBE2E3	131	Q969T4
KRYPCRQCEQSFHTP	ZNF592	1011	Q92610
YSCLLNQASHFRCPR	UBR1	1601	Q8IWV7
RDYTVLHPSCLSVCN	WAPL	356	Q7Z5K2
CPTHRNARKYLCQTL	TTC14	371	Q96N46
APVRVCDNCYEARNV	ZFYVE1	646	Q9HBF4
RTHTQERPYQCQLCG	ZIM2	486	Q9NZV7
QRTHVRVRPYECNEC	ZNF10	396	P21506
SISHVQQKPYRCNEC	ZNF221	161	Q9UK13
QRTHTGERPYACANC	ZNF316	906	A6NFI3
QRIHTTARPYECGQC	ZNF416	401	Q9BWM5
SPCQRYVSLENQHCE	ZCCHC4	381	Q9H5U6
QRIHTGERPYECSVC	ZNF548	356	Q8NEK5
VYCSPSLRCVQTAHN	UBASH3B	466	Q8TF42
LFQAQYRSSLTCPHC	USP31	281	Q70CQ4
CPLCHYSAVERNALN	ZNF142	221	P52746
HVCSRRQFPCYTQQI	WDR26	336	Q9H7D7
RQFPCYTQQILTEHC	WDR26	341	Q9H7D7
TFCERCLQNYIPAHS	TRIM2	41	Q9C040
PAESHQQLCCQRFER	SNX32	336	Q86XE0
VYFHCSALICNRLSP	ZP2	611	Q05996
PFREYQCHVDSCLQL	UIMC1	571	Q96RL1
RNVFHCEPANILYIC	SLFN5	596	Q08AF3
QRIHTGERPYQCAQC	ZNF467	291	Q7Z7K2
YRPHKCQECVRSFSR	ZNF473	456	Q8WTR7
RYINHSCAPNCVAEV	KMT2D	5471	O14686