Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioninterleukin-2 receptor binding

TIMM50 ECM1

8.53e-055592GO:0005134
GeneOntologyMolecularFunctionretromer complex binding

IGF2R RCSD1

3.80e-0410592GO:1905394
MousePhenoenlarged stomach

ANKRD20A4P ANKRD20A3P ANKRD20A8P ANKRD20A1

4.65e-0633484MP:0003883
DomainAnk_2

ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A1

4.46e-03215584PF12796
DomainTNFR/NGFR_Cys_rich_reg

LAMA5 TNFRSF18

4.70e-0333582IPR001368
DomainAnk

ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A1

5.48e-03228584PF00023
Domain-

ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A1

7.35e-032485841.25.40.20
DomainANK

ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A1

7.66e-03251584SM00248
DomainANK_REPEAT

ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A1

7.87e-03253584PS50088
DomainAnkyrin_rpt-contain_dom

ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A1

7.98e-03254584IPR020683
DomainANK_REP_REGION

ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A1

7.98e-03254584PS50297
Pubmed

Expression of testicular germ cell genes identified by differential display analysis.

ANKRD20A4P ANKRD20A3P ANKRD20A8P ANKRD20A1

5.96e-10861412634303
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TDRD3 IGF2R KMT2B FANCI HELZ2 LRRC56 LAMA5 BCL9 PLXNB2 ABCA7 CEP170B ZNF503 BAHCC1

5.00e-081105611335748872
Pubmed

TET2-mediated ECM1 hypomethylation promotes the neovascularization in active proliferative diabetic retinopathy.

TET2 ECM1

3.03e-06261238172938
Pubmed

Epigenomic analysis of gastrulation identifies a unique chromatin state for primed pluripotency.

TET2 KMT2B

9.07e-06361231844322
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

ADAMTS17 LAMA5 ECM1 PLXNB2 ITIH5

1.15e-0516761522159717
Pubmed

Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.

COL4A3 LAMA5 ECM1

1.30e-052661324742657
Pubmed

Laminin compensation in collagen alpha3(IV) knockout (Alport) glomeruli contributes to permeability defects.

COL4A3 LAMA5

1.81e-05461217699809
Pubmed

Laminin-1 reexpression in Alport mouse glomerular basement membranes.

COL4A3 LAMA5

1.81e-05461212631063
Pubmed

Human transcription factor protein interaction networks.

PHF2 TET2 LENG8 KMT2B RRP1B TIMM50 SLX4IP ZC3H18 MAP7 BCL9 ZNF503

3.42e-051429611135140242
Pubmed

DNA sequence and analysis of human chromosome 9.

ANKRD20A4P SH2D3C HEMGN ANKRD20A2P ANKRD20A3P ANKRD20A1

4.72e-0537061615164053
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

PHF2 LENG8 TDRD3 INTS6 KMT2B RRP1B HELZ2 LAMA5 MAP7 STAG2 CEP170B

5.21e-051497611131527615
Pubmed

Gelatinase B (MMP-9) is not essential in the normal kidney and does not influence progression of renal disease in a mouse model of Alport syndrome.

COL4A3 LAMA5

1.08e-04961210880400
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TET2 MYLK3 ATG13 PAK4 TIMM50 MAP7 CEP170B WNK4

1.26e-0486161836931259
Pubmed

MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity.

PAK4 MAP7 CEP170B

1.40e-045761329089450
Pubmed

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

COL4A3 LAMA5 ECM1 ITIH5

1.55e-0415361425037231
Pubmed

Forkhead transcription factor FoxF1 interacts with Fanconi anemia protein complexes to promote DNA damage response.

FANCI FOXF1

1.65e-041161226625197
Pubmed

Analysis of BCL6-interacting proteins by tandem mass spectrometry.

KMT2B HELZ2 WNK4

1.80e-046261316147992
Pubmed

Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins.

LENG8 LAMA5 CSMD3

1.89e-046361311572484
Pubmed

TRIM28 functions as a negative regulator of aggresome formation.

CTIF MAP7

1.97e-041261233783327
Pubmed

High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.

TET2 ZC3H18 MAP7 PLXNB2 ZNF503

2.06e-0430761537499664
Pubmed

Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane.

COL4A3 LAMA5

2.33e-041361212682087
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

PHF2 LENG8 RRP1B FANCI SLX4IP ZC3H18 SSX1 STAG2

2.53e-0495461836373674
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

COL4A3 LAMA5 ECM1 PLXNB2

2.58e-0417561428071719
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

TDRD3 KMT2B PCLO BRME1 ESX1 ANKRD20A3P AMER3

2.99e-0473661729676528
Pubmed

Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane.

COL4A3 LAMA5

3.13e-041561210625553
Pubmed

Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye.

COL4A3 LAMA5

3.13e-04156129264260
Pubmed

Interaction network of human early embryonic transcription factors.

TET2 KMT2B BCL9 ZNF503 BAHCC1

3.81e-0435161538297188
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

FANCI ZSCAN5C DEF8 LAMA5 STAG2

4.44e-0436361514691545
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KMT2B PCLO PLXNB2

4.90e-048761312465718
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

KMT2B FANCI TIMM50 LAMA5

5.53e-0421461422199357
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

TDRD3 PCLO CTIF CEP170B

5.92e-0421861433378226
Pubmed

PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα.

COL4A3 LAMA5

6.22e-042161227856617
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

PHF2 TET2 LENG8 KMT2B FANCI BCL9 STAG2 ZNF503

6.63e-04110361834189442
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

PHF2 KMT2B RRP1B FANCI ZC3H18 STAG2

6.84e-0460861636089195
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

PHF2 INTS6 TIMM50 ZC3H18 MAP7 ABCA7 CEP170B BAHCC1

7.15e-04111661831753913
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

PHF2 HELZ2 LAMA5 CTIF

9.86e-0425061433536335
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

IGF2R RRP1B FANCI HELZ2 ZC3H18 STAG2

9.90e-0465361622586326
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

IGF2R WFS1 FANCI LAMA5 MAP7 ECM1 PLXNB2 ABCA7

1.15e-03120161835696571
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

PHF2 TET2 MAP7 STAG2

1.35e-0327261431010829
Pubmed

Large-scale identification of genes implicated in kidney glomerulus development and function.

COL4A3 LAMA5

1.64e-033461216498405
Pubmed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

COL4A3 LAMA5 ITIH5

1.75e-0313561328675934
InteractionANKRD20A4P interactions

ANKRD20A4P ANKRD20A2P ANKRD20A1

4.99e-076603int:ANKRD20A4P
InteractionANKRD20A2P interactions

ANKRD20A4P ANKRD20A2P ANKRD20A1

8.71e-077603int:ANKRD20A2P
InteractionANKRD20A1 interactions

ANKRD20A4P ANKRD20A2P ANKRD20A1

4.07e-0611603int:ANKRD20A1
Cytoband9p12

ANKRD20A2P ANKRD20A3P

6.89e-04296129p12
CytobandEnsembl 112 genes in cytogenetic band chr16q24

DEF8 ZC3H18 FOXF1

8.07e-04136613chr16q24
GeneFamilyAnkyrin repeat domain containing

ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A1

8.39e-04242324403
CoexpressionBENPORATH_ES_WITH_H3K27ME3

TET2 ADAMTS17 SCUBE3 ESX1 RCSD1 ANKRD20A2P ANKRD20A3P ANKRD20A8P CSMD3 ANKRD20A1 FOXF1 ITIH5 ZNF503

1.37e-0611156113M10371
CoexpressionDESCARTES_FETAL_CEREBELLUM_VASCULAR_ENDOTHELIAL_CELLS

WFS1 SH2D3C HELZ2 HEMGN LYPD3 ECM1 FOXF1 ITIH5 ZNF503

1.73e-05645619M40158
CoexpressionBENPORATH_PRC2_TARGETS

TET2 ESX1 ANKRD20A2P ANKRD20A3P ANKRD20A8P CSMD3 ANKRD20A1 FOXF1 ZNF503

1.84e-05650619M8448
ToppCellAT1-AT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

COL4A3 WFS1 PCLO LAMA5 IQCN ABCA7

1.92e-071836166821dca076318115d360ff426eb1218cfe104063
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

COL4A3 PGGHG WFS1 LAMA5 ABCA7

2.71e-0616061558ed3a074932ccc951e07868dfdc61b99ae1cc2b
ToppCell368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|368C / Donor, Lineage, Cell class and subclass (all cells)

PAK4 SH2D3C LAMA5 ANKRD20A3P FOXF1

3.24e-0616661530a991fc3275b571d53bd0976df4789e5d40b01d
ToppCell368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|368C / Donor, Lineage, Cell class and subclass (all cells)

PAK4 SH2D3C LAMA5 ANKRD20A3P FOXF1

3.24e-0616661576b4cd32698900797ec009f17e50ea7ae36b85f4
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A3 INTS6 PGGHG WFS1 ABCA7

3.54e-06169615cd16e8462ee09877be962fbd9a3badcb825820b0
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_2|368C / Donor, Lineage, Cell class and subclass (all cells)

PHF2 SH2D3C ZBTB22 TNFRSF18 IQCN

4.81e-06180615551b8de8d933d11bcd3897aeb2fd033355f958e2
ToppCellAT1_cells-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A3 PGGHG WFS1 LAMA5 ABCA7

4.81e-06180615e1964002681f80d8d62406b6ee52a01e1829ccf2
ToppCellControl-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A1

5.35e-06184615c6affa0b12510363258f65e46bf2d47bf4a8e75f
ToppCellCOPD-Myeloid-cDC1|World / Disease state, Lineage and Cell class

ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A1

5.35e-0618461542d7ce104cd7bcb83fbbbd0e7d3267ad07edfa94
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)|343B / Donor, Lineage, Cell class and subclass (all cells)

COL4A3 PGGHG WFS1 LAMA5 ABCA7

5.35e-06184615cb15d6bae52c5ec251c2235859dc7e65f630ae23
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)-|343B / Donor, Lineage, Cell class and subclass (all cells)

COL4A3 PGGHG WFS1 LAMA5 ABCA7

5.35e-06184615bde4eaabd3e9bdaed23867d23a919b9d84b52d4b
ToppCellIPF-Myeloid-cDC1|World / Disease state, Lineage and Cell class

ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A1

5.64e-06186615962c2dada19185628ead77c32fcb07fa95114247
ToppCellControl-Myeloid-cDC1|Control / Disease state, Lineage and Cell class

ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A1

5.64e-06186615b05c394aa3573ba855abc3066739ca193883b0c3
ToppCellControl-Endothelial-VE_Capillary_A|Control / Disease state, Lineage and Cell class

SH2D3C LAMA5 ANKRD20A2P ANKRD20A3P FOXF1

5.79e-0618761554d7588172ac145ff5045ad9771636729ca3f0ca
ToppCellIPF-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A1

5.94e-0618861547bb6caf84f70a1cda7d09803afdfd5182772e66
ToppCellIPF-Myeloid-cDC1|IPF / Disease state, Lineage and Cell class

ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A1

5.94e-061886152331a2bae1383820d598e93aa86c75b101069bac
ToppCellE15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

IGF2R SH2D3C RCSD1 FOXF1 ITIH5

6.26e-0619061584fbd5664ec886120963d4f50dfa1fd1851d36c1
ToppCellCOPD-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A1

6.42e-061916153480e6d27dd4291765bbbb2acdb6a2e4f02c8085
ToppCellCOPD-Myeloid-cDC1|COPD / Disease state, Lineage and Cell class

ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A1

6.58e-06192615bd3d00b094d92463b06023361a71240851a542b8
ToppCellCOPD-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

ANKRD20A4P PAK4 ANKRD20A2P ANKRD20A3P FOXF1

7.46e-0619761530dbc05ea66892d2e18ff375ffa86d1db7bc4083
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A3 PGGHG WFS1 LAMA5 ABCA7

7.46e-06197615c9c968e223e7814cd8d22975d849a31b7e0af7aa
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A3 PGGHG WFS1 LAMA5 ABCA7

7.46e-06197615734b8db5bb4917c9ce92ed342fe6c22b64b0d3c5
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A3 PGGHG WFS1 LAMA5 ABCA7

7.46e-06197615e344455e62b3fe94bb242dc0db58d19a1d3878c7
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PAK4 SH2D3C LAMA5 FOXF1 ITIH5

7.83e-061996157ed541309808f15d65a9c4b26be2050e077539e6
ToppCell(7)_Epithelial_cells-(7)_Epithelial-I_(AT1)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

COL4A3 PGGHG WFS1 LAMA5 ABCA7

7.83e-061996155a002d49a8b84c158f7b4d7a3e78e6a937757bb7
ToppCellhealthy_donor-Lymphocytic-T_cell-CD4+_T_cell_(ISG_high)|healthy_donor / Disease condition, Lineage, Cell class and subclass

HELZ2 HEMGN SCUBE3 ANKRD20A1

3.86e-0513861497f5dc17522462133e582b508ad0ef036e656872
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 TDRD3 SCUBE3 WNK4

6.22e-051566144d2679e7639758c49fc25a2deb9109b08f0a3e57
ToppCellAT1_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A3 PGGHG WFS1 ABCA7

7.20e-05162614ae2ba4f21f6f6c512006fa531d670b88be7c04c9
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D3|343B / Donor, Lineage, Cell class and subclass (all cells)

PGGHG ADAMTS17 TNFRSF18 RCSD1

7.38e-051636148a4931c9fdaedcf6c319157821d3556cd25fc9e5
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TDRD3 PGGHG LAMA5 CEP170B

8.48e-05169614665b958f4a720ca369a8a0abc7fbe8b6e13c8ce5
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TDRD3 PGGHG LAMA5 CEP170B

8.48e-051696146614c9851537e4c21b1e45ff0cc3bad07ef9d034
ToppCelldroplet-Marrow-nan-18m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRME1 CTIF PLXNB2 BAHCC1

9.50e-0517461455cc8300489d11322724159ec7d0e1d32a702e91
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IGF2R RCSD1 CSMD3 ITIH5

9.71e-05175614fa16c6ba08dc0cc22e8cf049db0577811d080df6
ToppCellwk_15-18-Hematologic-Meg-ery-Primitive_erythrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ANKRD20A4P HEMGN ANKRD20A3P WNK4

9.92e-05176614664a7d15563428d0ae156d97aa88415fd0a0506a
ToppCell368C-Lymphocytic-NK_cells-NK_cell_E|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PHF2 PCLO BCAS1 ZNF503

1.01e-04177614946803293a7955116c80f403e99e4093e798ca3f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYLK3 WFS1 ECM1 ITIH5

1.06e-04179614c1c0b7186a0eab8c76404b95f1cf8d64b1b45cb1
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

COL4A3 PGGHG LAMA5 ABCA7

1.06e-04179614d5763912a4ce7188535675e338799b856edb9dda
ToppCellAT1_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A3 PGGHG WFS1 LAMA5

1.06e-041796141603117b52623663458a977c94bf7f9f6c1114b8
ToppCellfacs-Kidney-nan-24m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RRP1B HEMGN ECM1 ITIH5

1.08e-04180614f9f8245cbcdea18c15e2976c85b72c6807309787
ToppCellAT1_cells-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

COL4A3 WFS1 LAMA5 ABCA7

1.08e-041806142d52cb5f77dde0e3dccac1333d4ec67ec680fcb2
ToppCellAT1_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

COL4A3 WFS1 LAMA5 ABCA7

1.08e-04180614ff4728782c3ec814ba071cc22b7894abdd9da837
ToppCellAT1-AT2_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

COL4A3 WFS1 LAMA5 ABCA7

1.11e-04181614ca23ce4f2c7b684d8ddd0e8619b3b696023d75e3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WFS1 SH2D3C TNFRSF18 RCSD1

1.13e-0418261441b070085edba7a58b81c20aa4942d06f745acf8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WFS1 SH2D3C TNFRSF18 RCSD1

1.13e-041826145e9a67b2de0daa4fdc344b10a857d8a901ad810e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WFS1 SH2D3C TNFRSF18 RCSD1

1.13e-04182614b0fe042c71d6ab8c75abd7ba9d2de00b72d01c0c
ToppCellCOVID-19-lung-AT1|COVID-19 / Disease (COVID-19 only), tissue and cell type

COL4A3 PGGHG WFS1 LAMA5

1.15e-041836147b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCellwk_15-18-Epithelial-PNS-intermediate_Schwann|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ANKRD20A4P BCAS1 ANKRD20A1 ITIH5

1.15e-04183614d874aa9a856f79626c8a8371f6196a77b7d662ee
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 TET2 MYLK3 ITIH5

1.15e-04183614eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-ILCP|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A3 TNFRSF18 RCSD1 BCAS1

1.15e-041836144a1e5bf58d2acd9dbceeef538b6851c1e5e91059
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PHF2 ZBTB22 TNFRSF18 IQCN

1.15e-04183614fef51dcf180e6d4e136362c7e140ec5ef372e6d0
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PGGHG WFS1 LAMA5 ABCA7

1.18e-04184614c7073d1b2c4fdb154d87678b92a0629c02116972
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-ACTC+_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ANKRD20A4P ANKRD20A3P ANKRD20A1 FOXF1

1.18e-0418461439168ca2bbf1369c9fe87c67f0aaff5e3cd03151
ToppCellwk_15-18-Hematologic-Meg-ery-Cycling_definitive_erythroblast|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FANCI HEMGN ABCA7 ANKRD20A1

1.18e-04184614238eba615b4e04967d44ac7858a6673bdd7f67e9
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PGGHG WFS1 LAMA5 ABCA7

1.18e-041846141ed558a88215b248431c524ea16f13d9022ae98c
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A3 PGGHG WFS1 LAMA5

1.20e-041856141c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellControl-Epithelial-ATI|World / Disease state, Lineage and Cell class

COL4A3 PGGHG WFS1 LAMA5

1.20e-041856140563d5042bb96ecce8446fbf26d05ef7a45e23c5
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PCLO AMER3 ABCA7 WNK4

1.20e-04185614d42f6722a6771752cd744146a09e2ead9b7252bc
ToppCellControl-Endothelial-VE_Capillary_A|World / Disease state, Lineage and Cell class

SH2D3C ANKRD20A2P ANKRD20A3P FOXF1

1.20e-04185614a28187c2fd23564314b35759479ff2ca21f61485
ToppCellControl-Myeloid-cDC1|World / Disease state, Lineage and Cell class

ANKRD20A4P ANKRD20A2P ANKRD20A3P ANKRD20A1

1.23e-041866143de803dee3ef10eb85a2b47d3f93385214e5b0ff
ToppCellPCW_07-8.5-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-erythro|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

HEMGN ANKRD20A8P WNK4 ANKRD20A1

1.23e-041866146078aa16261554c7fd41137b8de1362d15b30490
ToppCellControl-Epithelial-ATI|Control / Disease state, Lineage and Cell class

COL4A3 PGGHG WFS1 LAMA5

1.25e-04187614fdd1c57b61ca9392ac27661a82729f37593df63c
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SH2D3C RCSD1 CTIF ITIH5

1.28e-0418861473f6ec915934154f435a376cb274b058ff7c5f35
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A3 PGGHG WFS1 AMER3

1.28e-04188614e9cef856a96a97afac5ecafe2ee91eff0d731e01
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 MYLK3 ECM1 ITIH5

1.28e-041886149db778c1d9e622a68337212296e3a1ed8f771fa5
ToppCellAT1-AT2_cells-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A3 PGGHG WFS1 ABCA7

1.28e-04188614be710bc957118cf426dd71c2d57e6f1b41c9a467
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 MYLK3 ECM1 ITIH5

1.28e-04188614047c4e0b03fc8334e38c48977e41d26dbe229d47
ToppCelltumor_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

IGF2R SH2D3C LAMA5 RCSD1

1.31e-041896149c407b17d7945e81e1ae6c18452f5d20fb09d563
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

IGF2R RCSD1 FOXF1 ITIH5

1.33e-041906142ab604d35456beba71c25511e0f819000e6642d2
ToppCellLPS-IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SH2D3C RCSD1 CTIF ITIH5

1.33e-04190614106ea0bb7b99c697ffc5443d72343df2484250c7
ToppCellLAM-Epithelial-AT1|Epithelial / Condition, Lineage and Cell class

COL4A3 WFS1 LAMA5 ABCA7

1.36e-041916143457e15d1e9b36a78363d46b320c4ec46b40290a
ToppCellLAM-Epithelial-AT1|LAM / Condition, Lineage and Cell class

COL4A3 WFS1 LAMA5 ABCA7

1.36e-0419161466875b2ec2c510489407f3e433a90cdf74a15094
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SH2D3C RCSD1 CTIF ITIH5

1.39e-04192614c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCellAT1_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

COL4A3 WFS1 LAMA5 ABCA7

1.39e-041926140444f9e9cef7403e220e862b5a787443d3f5c9ac
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WFS1 PCLO PLXNB2 CEP170B

1.41e-04193614471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCell(6)_Endothelial-C_(Capillary_Aerocyte_)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

PAK4 SH2D3C LAMA5 FOXF1

1.41e-04193614f7f2dc6aff02d096a282835094d26d12b3b73e61
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WFS1 PCLO PLXNB2 CEP170B

1.41e-04193614fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

TET2 RCSD1 MAP7 ECM1

1.44e-0419461458046894446cb250814252a23f60fdd59c114d77
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A3 PGGHG WFS1 ABCA7

1.47e-0419561468f4cc84b5ae7f4159b780c78e4b66c94211779a
ToppCellnormal_Lung-Epithelial_cells-AT1|normal_Lung / Location, Cell class and cell subclass

COL4A3 WFS1 LAMA5 ABCA7

1.47e-04195614569d1ebc5a5aa110a2430b096755ae35354040c4
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 SCUBE3 WNK4 ZNF503

1.47e-0419561460d08fb27469d1e247bc47b651d7023ba82cf92f
ToppCellAT1_cells|World / lung cells shred on cell class, cell subclass, sample id

COL4A3 WFS1 LAMA5 ABCA7

1.47e-04195614792d6a49b0a875a00569071183d195287a9925c5
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A3 PGGHG WFS1 ABCA7

1.47e-041956142a1863f4b9fe73c30b0b1acf9b12fc98ef65040f
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CSMD3 ECM1 FOXF1 ZNF503

1.47e-04195614bad7f2162000f29488b3c4b903dcac9a818621f7
ToppCellAT1|World / shred by cell class for parenchyma

COL4A3 FANCI LAMA5 ABCA7

1.50e-041966142bc487f8a109a6961ebff111dec79c2227ea60ac
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL4A3 PGGHG WFS1 ABCA7

1.50e-041966146731fef8c148b6681d6ed38afdf23c8213e0bbbe
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 SCUBE3 WNK4 ZNF503

1.50e-04196614f40d10ea7714067585493fdc89744714aa427de8
ToppCellEpithelial_cells-AT1_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

COL4A3 WFS1 LAMA5 ABCA7

1.50e-041966146c99d29162848161c1f166a032320f87a5d5a631
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A3 PGGHG WFS1 ABCA7

1.50e-04196614eb68f7954e7c2f86d05e740e95b6e74805a6053f
ToppCell(7)_Epithelial-I_(AT1)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

COL4A3 WFS1 LAMA5 ABCA7

1.50e-04196614150554fa06868d29b0608189862eef6505ba757f
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL4A3 PGGHG WFS1 ABCA7

1.50e-041966146856317cd0cdcb88fe54b4ae905d91e13495b1c4
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 SCUBE3 WNK4 ZNF503

1.50e-04196614b8350340d86e4524e9616a427e7f2e116a6fb3be
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_aerocyte_capillary-EC_aerocyte_capillary_L.2.0.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PAK4 SH2D3C RCSD1 FOXF1

1.53e-0419761486591849476b3925857a82b6913f65e74df200c1
ToppCellAT1_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

COL4A3 WFS1 LAMA5 ABCA7

1.53e-0419761480d81be244c94c435accb643449b4ce6a3462c7f
ToppCelldroplet-Mammary_Gland-nan-3m-Epithelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RRP1B LYPD3 LAMA5 CEP170B

1.53e-04197614b1c6a15bf6c0645952a7247182dc71baf4736869
ToppCellnormal_Lung-Epithelial_cells-AT1|Epithelial_cells / Location, Cell class and cell subclass

COL4A3 WFS1 LAMA5 ABCA7

1.53e-041976147d19b93d6853828e2a036e37c4887edb1de4503c
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

COL4A3 PGGHG WFS1 LAMA5

1.53e-0419761469d5b8588046d119b5dff9a7fd6f49e97e00a5b7
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

COL4A3 PGGHG WFS1 LAMA5

1.53e-04197614e6cbfa267eb2e05b441fd034786faae07bb0e081
ToppCellBiopsy_IPF-Epithelial-AT1|Biopsy_IPF / Sample group, Lineage and Cell type

COL4A3 WFS1 LAMA5 ABCA7

1.56e-0419861475bdecbe111fededf6082b11de18b84ca308ef6d
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCUBE3 CSMD3 ECM1 FOXF1

1.56e-0419861409be07ebfc3e49c3858e9b74605b69cf4fc28b56
ToppCellAT1-AT2_cells|World / lung cells shred on cell class, cell subclass, sample id

COL4A3 WFS1 LAMA5 ABCA7

1.56e-04198614a5b3617ea2ed4bffba59edcf6284799c2b3bbb29
DiseaseMYELODYSPLASTIC SYNDROME

TET2 FANCI STAG2

2.70e-0467553C3463824
DiseaseCongenital hernia of foramen of Morgagni

IGF2R FOXF1

5.72e-0419552C0265699
DiseaseCongenital hernia of foramen of Bochdalek

IGF2R FOXF1

5.72e-0419552C0265700
DiseaseCongenital diaphragmatic hernia

IGF2R FOXF1

7.00e-0421552C0235833
Diseasespermatogenic failure (is_implicated_in)

IQCN SSX1

8.42e-0423552DOID:0111910 (is_implicated_in)
DiseaseHematopoetic Myelodysplasia

TET2 STAG2

1.34e-0329552C2713368
Diseasethyroid carcinoma

DBX1 HEMGN

2.42e-0339552EFO_0002892
DiseaseLiver carcinoma

IGF2R KMT2B FANCI SSX1 ECM1

2.52e-03507555C2239176

Protein segments in the cluster

PeptideGeneStartEntry
VNGQGEGPPAKHPSL

ANKRD20A1

321

Q5TYW2
PGGQQRPHSEKGPQA

AMER3

41

Q8N944
GGGGHEPEQQQEEPP

ESX1

76

Q8N693
PGHQDPLGGKAPQAC

BAHCC1

506

Q9P281
KEGGVPLAPNQPVHG

ATG13

306

O75143
VNGQGEGPPAKHPSL

ANKRD20A8P

321

Q5CZ79
GHPGVPPNAVLSGEK

CSMD3

2996

Q7Z407
PGGNKPQQHGDHQPG

CTIF

201

O43310
QGDKGNPGPSEISHV

COL4A3

936

Q01955
VNGQGEGPPAKHPSL

ANKRD20A4P

321

Q4UJ75
GQNGEEKSPPNASHP

RCSD1

61

Q6JBY9
EHQGLPVPGSPGGQK

CEP170B

646

Q9Y4F5
LGNNQVPGGKDDPPL

ADAMTS17

321

Q8TE56
AGVGVDPAPGLQHPK

ABCA7

2116

Q8IZY2
PQPHGHVPGKTTQGG

IQCN

806

Q9H0B3
HIGGKGPPAPTTQAQ

INTS6

676

Q9UL03
PSGFKSGQHPLNGQP

LUZP4

96

Q9P127
VNGQGEGPPAKHPSL

ANKRD20A2P

321

Q5SQ80
TGHVSGPDGQNPEKI

FANCI

856

Q9NVI1
TNAPGNGKPVGSPHV

MAP7

646

Q14244
NGELIGAPAPPNGHK

ITIH5

721

Q86UX2
GQHSGFGPQPNPEKV

LENG8

256

Q96PV6
FGPQPNPEKVQNHSG

LENG8

261

Q96PV6
AQQPGHEKSQPGPAK

PCLO

316

Q9Y6V0
KPLSVEPQQGPQAGG

PLXNB2

896

O15031
QQGKSPGAGNPEPEQ

MYLK3

446

Q32MK0
PHPDLSDVGQKGPGN

DBX1

261

A6NMT0
GEGQEEPPLNPHGAA

KMT2B

2496

Q9UMN6
GHTLTPEQPGGPQQE

PGGHG

161

Q32M88
SQQHQVPVPGGPVGH

LAMA5

2146

O15230
PHQETGGPQGQDPKA

HEMGN

426

Q9BXL5
GGPQQPHNKGCVAPT

LYPD3

316

O95274
VNGQGEGPPAKHPSL

ANKRD20A3P

321

Q5VUR7
PEGKLGPVPSTQQHG

BRME1

46

Q0VDD7
GPVPSTQQHGEEPGK

BRME1

51

Q0VDD7
GGPQQNPGVLDGPQK

BCL9

386

O00512
KQSGPRQHEQGPGEE

DEF8

81

Q6ZN54
QHPNEQKEGTPAPFG

ECM1

121

Q16610
FHKSNQEQVQPGGPP

HELZ2

2191

Q9BYK8
PGQDTDKTPGHAPAQ

BCAS1

146

O75363
GQCPPGQHSVDGFKP

SCUBE3

691

Q8IX30
QGEPHDVAPNGPSAG

PAK4

221

O96013
MSSAPEKQQPPHGGG

FOXF1

1

Q12946
LPPPRQGKEGQENGH

IGF2R

2376

P11717
KHHLQPENPGPGGAA

RRP1B

406

Q14684
KHNRSNIGTEGGPPP

TDRD3

76

Q9H7E2
HGPGQAPDVKPVQNG

PHF2

71

O75151
QGLHNPCPQSKGPGS

LRRC56

26

Q8IYG6
GPQNDGKQLHPPGKA

SSX1

131

Q16384
TQPEDTSGQQKPHPG

SLX4IP

246

Q5VYV7
TKAQGPQQQPGSEGP

TIMM50

46

Q3ZCQ8
GKPPSGPNRMNGHHQ

STAG2

61

Q8N3U4
HHPCPPGQGVQSQGK

TNFRSF18

91

Q9Y5U5
NVDVNQHPDGGPGGK

ZNF503

291

Q96F45
QAQEAGPKPNLVPGG

SH2D3C

96

Q8N5H7
PTGRNHGENSQEKPP

TOGARAM1

876

Q9Y4F4
PDQGGSHTQTPPQKD

TET2

931

Q6N021
GKEPQVGGSPQPLSH

WNK4

1091

Q96J92
GQAEINPVHSPGPAG

ZSCAN5C

326

A6NGD5
PGQPPGNQAEHGAVT

ZBTB22

441

O15209
PPGQPQQGTFVAHKE

ZC3H18

801

Q86VM9
QVNEHDGGAQPGPVP

WFS1

206

O76024
PAPSGAAAEHGQKPQ

NEXN-AS1

136

Q8NBZ9