Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal protein binding

SPTBN5 DLG5 BICDL1 DLC1 KIF15 SPTA1 SYNE2 CEP135 DAAM2 ACTN2 PLEC JAKMIP2 KIF3A

5.30e-0510996613GO:0008092
GeneOntologyMolecularFunctionstructural molecule activity

NEFL KRT74 SPTA1 ERC2 MATN4 LTBP2 LMNB2 ACTN2 PLEC BSN PRPH

1.49e-048916611GO:0005198
GeneOntologyMolecularFunctionstructural constituent of presynaptic active zone

ERC2 BSN

2.97e-048662GO:0098882
GeneOntologyMolecularFunctionstructural constituent of synapse

NEFL ERC2 BSN

3.61e-0442663GO:0098918
GeneOntologyMolecularFunctiondynactin binding

SPTBN5 BICDL1

6.95e-0412662GO:0034452
GeneOntologyMolecularFunctionstructural constituent of cytoskeleton

NEFL SPTA1 LMNB2 PLEC

9.05e-04130664GO:0005200
GeneOntologyBiologicalProcessmicrotubule-based movement

FSIP2 NEFL BICDL1 KIF15 CCDC146 SYNE2 KXD1 CATSPER3 BSN KIF3A

3.53e-064936610GO:0007018
GeneOntologyBiologicalProcesscell junction organization

ARHGAP22 NEFL DLG5 DLC1 MYCBP2 PPFIA1 SLIT1 ERC2 ACTN2 PLEC BSN FBXO45 CDH15

1.07e-059746613GO:0034330
GeneOntologyBiologicalProcessorganelle transport along microtubule

NEFL BICDL1 SYNE2 KXD1 KIF3A

1.48e-0597665GO:0072384
GeneOntologyBiologicalProcessmicrotubule-based process

FSIP2 NEFL BICDL1 KIF15 CCDC146 PPP1R12A CNTRL SYNE2 KXD1 CEP135 CATSPER3 BSN KIF3A

2.56e-0510586613GO:0007017
GeneOntologyBiologicalProcesstransport along microtubule

NEFL BICDL1 SYNE2 KXD1 BSN KIF3A

3.97e-05197666GO:0010970
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

FSIP2 TBC1D31 TCHP CCDC146 CNTRL SYNE2 CEP135 DAAM2 ACTN2 KIF3A

5.00e-056706610GO:0120031
GeneOntologyBiologicalProcesscell projection assembly

FSIP2 TBC1D31 TCHP CCDC146 CNTRL SYNE2 CEP135 DAAM2 ACTN2 KIF3A

6.01e-056856610GO:0030031
GeneOntologyBiologicalProcessregulation of organelle organization

SPTBN5 DLC1 TCHP MYCBP2 RPS6KA2 SPTA1 PPFIA1 SYNE2 MAD1L1 CEP135 ERC2 DAAM2 ACTN2 MAP3K4

7.20e-0513426614GO:0033043
GeneOntologyBiologicalProcesscell junction assembly

DLG5 DLC1 MYCBP2 SLIT1 ACTN2 PLEC BSN FBXO45 CDH15

7.93e-05569669GO:0034329
GeneOntologyBiologicalProcesscytoskeleton-dependent intracellular transport

NEFL BICDL1 SYNE2 KXD1 BSN KIF3A

8.30e-05225666GO:0030705
GeneOntologyBiologicalProcesscilium assembly

FSIP2 TBC1D31 TCHP CCDC146 CNTRL SYNE2 CEP135 KIF3A

8.33e-05444668GO:0060271
GeneOntologyBiologicalProcesscilium organization

FSIP2 TBC1D31 TCHP CCDC146 CNTRL SYNE2 CEP135 KIF3A

1.35e-04476668GO:0044782
GeneOntologyBiologicalProcesscentral nervous system projection neuron axonogenesis

MYCBP2 SZT2 FBXO45

1.45e-0432663GO:0021952
GeneOntologyBiologicalProcessmaintenance of presynaptic active zone structure

ERC2 BSN

1.50e-046662GO:0048790
GeneOntologyBiologicalProcessmicrotubule-based transport

NEFL BICDL1 SYNE2 KXD1 BSN KIF3A

1.58e-04253666GO:0099111
GeneOntologyBiologicalProcessnuclear migration

SYNE2 SLIT1 LMNB2

1.74e-0434663GO:0007097
GeneOntologyBiologicalProcessintermediate filament cytoskeleton organization

NEFL KRT74 PLEC PRPH

2.86e-0499664GO:0045104
GeneOntologyBiologicalProcessintermediate filament-based process

NEFL KRT74 PLEC PRPH

2.98e-04100664GO:0045103
GeneOntologyBiologicalProcesssynapse organization

ARHGAP22 NEFL DLG5 MYCBP2 PPFIA1 SLIT1 ERC2 BSN FBXO45

3.18e-04685669GO:0050808
GeneOntologyBiologicalProcessestablishment of organelle localization

NEFL BICDL1 SYNE2 SLIT1 MAD1L1 KXD1 LMNB2 KIF3A

3.41e-04546668GO:0051656
GeneOntologyBiologicalProcesscentral nervous system neuron axonogenesis

MYCBP2 SZT2 FBXO45

3.52e-0443663GO:0021955
GeneOntologyBiologicalProcessnucleus localization

SYNE2 SLIT1 LMNB2

3.77e-0444663GO:0051647
GeneOntologyBiologicalProcessorganelle localization

NEFL BICDL1 SYNE2 SLIT1 MAD1L1 KXD1 LMNB2 BSN KIF3A

3.84e-04703669GO:0051640
GeneOntologyBiologicalProcessnegative regulation of organelle organization

SPTBN5 DLC1 TCHP RPS6KA2 SPTA1 PPFIA1 MAD1L1

3.88e-04421667GO:0010639
GeneOntologyBiologicalProcessregulation of actin filament organization

SPTBN5 DLC1 SPTA1 PPFIA1 DAAM2 ACTN2

3.93e-04300666GO:0110053
GeneOntologyBiologicalProcessregulation of cellular component size

SPTBN5 NEFL SPTA1 SLIT1 KXD1 DAAM2 ACTN2

4.16e-04426667GO:0032535
GeneOntologyBiologicalProcesspresynaptic active zone organization

ERC2 BSN

4.46e-0410662GO:1990709
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

FSIP2 NEFL KIF15 CCDC146 PPP1R12A CNTRL SYNE2 CEP135 KIF3A

4.57e-04720669GO:0000226
GeneOntologyBiologicalProcesstelencephalon development

NEFL SZT2 SYNE2 SLIT1 FBXO45 KIF3A

6.71e-04332666GO:0021537
GeneOntologyBiologicalProcesshippo signaling

DLG5 AMOTL1 WWC1

7.29e-0455663GO:0035329
GeneOntologyBiologicalProcessintracellular transport

SPTBN5 NEFL BICDL1 PPP1R12A SYNE2 SLIT1 KXD1 LMNB2 ACTN2 RAB11FIP4 BSN WWC1 KIF3A

7.97e-0414966613GO:0046907
GeneOntologyBiologicalProcessgerm cell development

FSIP2 CCDC146 TCP11 RPS6KA2 CNTRL CATSPER3 PRMT7

8.63e-04482667GO:0007281
GeneOntologyBiologicalProcesssupramolecular fiber organization

SPTBN5 NEFL DLC1 KRT74 SPTA1 PPFIA1 DAAM2 LTBP2 ACTN2 PLEC

8.77e-049576610GO:0097435
GeneOntologyBiologicalProcessorganelle assembly

FSIP2 TBC1D31 KIF15 TCHP CCDC146 CNTRL SYNE2 CEP135 ACTN2 PLEC KIF3A

9.01e-0411386611GO:0070925
GeneOntologyBiologicalProcessforebrain development

NEFL DLC1 SZT2 SYNE2 SLIT1 FBXO45 KIF3A

9.39e-04489667GO:0030900
GeneOntologyBiologicalProcessregulation of actin filament depolymerization

SPTBN5 SPTA1 ACTN2

9.86e-0461663GO:0030834
GeneOntologyBiologicalProcessadherens junction organization

DLG5 PLEC CDH15

9.86e-0461663GO:0034332
GeneOntologyBiologicalProcesscentriole-centriole cohesion

CEP135 KIF3A

1.03e-0315662GO:0010457
GeneOntologyBiologicalProcessactin filament organization

SPTBN5 DLC1 SPTA1 PPFIA1 DAAM2 ACTN2 PLEC

1.18e-03509667GO:0007015
GeneOntologyBiologicalProcessactin filament depolymerization

SPTBN5 SPTA1 ACTN2

1.24e-0366663GO:0030042
GeneOntologyBiologicalProcessregulation of cellular component biogenesis

SPTBN5 DLG5 DLC1 TCHP MYCBP2 SPTA1 PPFIA1 SYNE2 SLIT1 CEP135 DAAM2

1.29e-0311896611GO:0044087
GeneOntologyBiologicalProcesscell morphogenesis

NEFL DLC1 MYCBP2 SZT2 CCDC146 SPTA1 SLIT1 PLEC FBXO45 CDH15 KIF3A

1.33e-0311946611GO:0000902
GeneOntologyBiologicalProcessregulation of actin cytoskeleton organization

SPTBN5 DLC1 SPTA1 PPFIA1 DAAM2 ACTN2

1.42e-03384666GO:0032956
GeneOntologyBiologicalProcesscellular process involved in reproduction in multicellular organism

FSIP2 CCDC146 TCP11 RPS6KA2 CNTRL CATSPER3 PRMT7

1.45e-03527667GO:0022412
GeneOntologyCellularComponentcortical cytoskeleton

SPTBN5 DLC1 SPTA1 ERC2 ACTN2 BSN

3.93e-06129686GO:0030863
GeneOntologyCellularComponentpresynaptic cytoskeleton

NEFL ERC2 BSN

1.17e-0514683GO:0099569
GeneOntologyCellularComponentcell cortex region

SPTBN5 TCHP ERC2 BSN

1.38e-0545684GO:0099738
GeneOntologyCellularComponentintermediate filament cytoskeleton

NEFL TCHP KRT74 SYNE2 LMNB2 PLEC PRPH

2.32e-05263687GO:0045111
GeneOntologyCellularComponentcentrosome

BICDL1 TBC1D31 KIF15 TCHP CCDC146 PPP1R12A CNTRL MAD1L1 CEP135 RAB11FIP4 KIF3A

3.56e-057706811GO:0005813
GeneOntologyCellularComponentmicrotubule organizing center

DLG5 BICDL1 TBC1D31 KIF15 TCHP CCDC146 PPP1R12A CNTRL MAD1L1 CEP135 RAB11FIP4 KIF3A

3.64e-059196812GO:0005815
GeneOntologyCellularComponentanchoring junction

ARHGAP22 DLG5 DLC1 TCHP PPP1R12A PPFIA1 ANXA6 SYNE2 AMOTL1 ACTN2 PLEC CDH15

6.51e-059766812GO:0070161
GeneOntologyCellularComponentfocal adhesion

ARHGAP22 DLC1 PPP1R12A PPFIA1 ANXA6 SYNE2 ACTN2 PLEC

7.67e-05431688GO:0005925
GeneOntologyCellularComponentcell-substrate junction

ARHGAP22 DLC1 PPP1R12A PPFIA1 ANXA6 SYNE2 ACTN2 PLEC

9.28e-05443688GO:0030055
GeneOntologyCellularComponentintermediate filament

NEFL TCHP KRT74 LMNB2 PLEC PRPH

9.58e-05227686GO:0005882
GeneOntologyCellularComponentcytoplasmic region

SPTBN5 NEFL TCHP CNTRL ERC2 BSN KIF3A

1.67e-04360687GO:0099568
GeneOntologyCellularComponentcell cortex

SPTBN5 DLC1 TCHP SPTA1 ERC2 ACTN2 BSN

2.00e-04371687GO:0005938
GeneOntologyCellularComponentcortical actin cytoskeleton

SPTBN5 DLC1 SPTA1 ACTN2

2.40e-0493684GO:0030864
GeneOntologyCellularComponentcytoskeleton of presynaptic active zone

ERC2 BSN

2.88e-048682GO:0048788
GeneOntologyCellularComponentspectrin

SPTBN5 SPTA1

3.70e-049682GO:0008091
GeneOntologyCellularComponentsupramolecular fiber

NEFL DLC1 KIF15 TCHP KRT74 PPP1R12A SYNE2 LMNB2 ACTN2 PLEC KIF3A PRPH

3.79e-0411796812GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

NEFL DLC1 KIF15 TCHP KRT74 PPP1R12A SYNE2 LMNB2 ACTN2 PLEC KIF3A PRPH

4.03e-0411876812GO:0099081
GeneOntologyCellularComponentapical cortex

SPTBN5 TCHP

4.61e-0410682GO:0045179
GeneOntologyCellularComponentaxon

NEFL MYCBP2 SPTA1 PPFIA1 ERC2 GRIA3 PLEC BSN KIF3A PRPH

5.80e-048916810GO:0030424
GeneOntologyCellularComponentcilium

SPTBN5 FSIP2 DLG5 TBC1D31 TCHP TCP11 CNTRL CATSPER3 KIF3A PRPH

6.17e-048986810GO:0005929
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

NEFL DLC1 KIF15 TCHP KRT74 LMNB2 ACTN2 PLEC KIF3A PRPH

6.22e-048996810GO:0099513
GeneOntologyCellularComponentneurofilament

NEFL PRPH

9.25e-0414682GO:0005883
GeneOntologyCellularComponentpresynaptic active zone

PPFIA1 ERC2 GRIA3 BSN

1.16e-03141684GO:0048786
GeneOntologyCellularComponentaxon cytoplasm

NEFL BSN KIF3A

1.42e-0368683GO:1904115
GeneOntologyCellularComponentZ disc

PPP1R12A SYNE2 ACTN2 PLEC

1.49e-03151684GO:0030018
GeneOntologyCellularComponentsperm head-tail coupling apparatus

FSIP2 CCDC146

1.54e-0318682GO:0120212
GeneOntologyCellularComponentmeiotic spindle

RPS6KA2 CNTRL

1.72e-0319682GO:0072687
GeneOntologyCellularComponentI band

PPP1R12A SYNE2 ACTN2 PLEC

2.10e-03166684GO:0031674
GeneOntologyCellularComponentpresynaptic active zone cytoplasmic component

ERC2 BSN

2.52e-0323682GO:0098831
GeneOntologyCellularComponentpostsynaptic cytoskeleton

NEFL ACTN2

3.22e-0326682GO:0099571
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

SPTBN5 NEFL CNTRL BSN KIF3A

3.71e-03317685GO:0032838
GeneOntologyCellularComponentterminal bouton

ERC2 GRIA3 PRPH

3.79e-0396683GO:0043195
GeneOntologyCellularComponentspindle

KIF15 RPS6KA2 CNTRL MAD1L1 RAB11FIP4 KIF3A

4.27e-03471686GO:0005819
GeneOntologyCellularComponentribbon synapse

BSN KIF3A

4.86e-0332682GO:0097470
GeneOntologyCellularComponentglutamatergic synapse

ARHGAP22 DLG5 ERC2 GRIA3 ACTN2 BSN FBXO45 KIF3A

4.90e-03817688GO:0098978
GeneOntologyCellularComponentneuron projection cytoplasm

NEFL BSN KIF3A

5.54e-03110683GO:0120111
DomainSpectrin_repeat

SPTBN5 SPTA1 SYNE2 ACTN2 PLEC

5.25e-0829665IPR002017
DomainSpectrin/alpha-actinin

SPTBN5 SPTA1 SYNE2 ACTN2 PLEC

8.83e-0832665IPR018159
DomainSPEC

SPTBN5 SPTA1 SYNE2 ACTN2 PLEC

8.83e-0832665SM00150
DomainActinin_actin-bd_CS

SPTBN5 SYNE2 ACTN2 PLEC

1.20e-0623664IPR001589
DomainSpectrin

SPTBN5 SPTA1 SYNE2 ACTN2

1.20e-0623664PF00435
DomainACTININ_2

SPTBN5 SYNE2 ACTN2 PLEC

1.20e-0623664PS00020
DomainACTININ_1

SPTBN5 SYNE2 ACTN2 PLEC

1.20e-0623664PS00019
DomainIntermediate_filament_CS

NEFL KRT74 LMNB2 PRPH

7.24e-0563664IPR018039
DomainCH

SPTBN5 SYNE2 ACTN2 PLEC

8.19e-0565664SM00033
DomainCH

SPTBN5 SYNE2 ACTN2 PLEC

1.09e-0470664PF00307
DomainFilament

NEFL KRT74 LMNB2 PRPH

1.16e-0471664SM01391
Domain-

SPTBN5 SYNE2 ACTN2 PLEC

1.16e-04716641.10.418.10
DomainIF

NEFL KRT74 LMNB2 PRPH

1.22e-0472664PS00226
DomainCH

SPTBN5 SYNE2 ACTN2 PLEC

1.29e-0473664PS50021
DomainFilament

NEFL KRT74 LMNB2 PRPH

1.29e-0473664PF00038
DomainCH-domain

SPTBN5 SYNE2 ACTN2 PLEC

1.43e-0475664IPR001715
DomainIF

NEFL KRT74 LMNB2 PRPH

1.51e-0476664IPR001664
DomainEF-hand_Ca_insen

SPTA1 ACTN2

1.83e-046662IPR014837
DomainEFhand_Ca_insen

SPTA1 ACTN2

1.83e-046662PF08726
DomainFilament_head

NEFL PRPH

2.55e-047662PF04732
DomainIntermed_filament_DNA-bd

NEFL PRPH

2.55e-047662IPR006821
DomainSPRY

BTN3A3 RNF123 FBXO45

3.62e-0387663SM00449
DomainSPRY

BTN3A3 RNF123 FBXO45

4.49e-0394663PF00622
DomainSPRY_dom

BTN3A3 RNF123 FBXO45

4.49e-0394663IPR003877
DomainB30.2/SPRY

BTN3A3 RNF123 FBXO45

4.63e-0395663IPR001870
DomainB302_SPRY

BTN3A3 RNF123 FBXO45

4.63e-0395663PS50188
DomainEGF-type_Asp/Asn_hydroxyl_site

SLIT1 MATN4 LTBP2

6.27e-03106663IPR000152
DomainConA-like_dom

BTN3A3 RNF123 SLIT1 FBXO45

7.52e-03219664IPR013320
DomainEGF_CA

SLIT1 MATN4 LTBP2

9.23e-03122663SM00179
DomainEGF-like_Ca-bd_dom

SLIT1 MATN4 LTBP2

9.64e-03124663IPR001881
DomainEGF

SLIT1 MATN4 LTBP2

1.01e-02126663PF00008
DomainSAM_2

DLC1 PPFIA1

1.01e-0243662PF07647
DomainKinesin-like_fam

KIF15 KIF3A

1.01e-0243662IPR027640
PathwayREACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS

NEFL RPS6KA2 GRIA3 ACTN2

7.92e-0635524MM15109
PathwayREACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION

NEFL GRIA3 ACTN2

6.01e-0521523M838
PathwayREACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION

NEFL GRIA3 ACTN2

6.94e-0522523MM15104
PathwayREACTOME_CREB1_PHOSPHORYLATION_THROUGH_NMDA_RECEPTOR_MEDIATED_ACTIVATION_OF_RAS_SIGNALING

NEFL RPS6KA2 ACTN2

1.45e-0428523M837
PathwayREACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS

NEFL RPS6KA2 GRIA3 ACTN2

3.93e-0494524M2843
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SPTBN5 SPTA1

5.89e-0410522MM15112
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NEFL KIF15 MYCBP2 PPP1R12A RPS6KA2 PPFIA1 SYNE2 MAD1L1 ERC2 GRIA3 LMNB2 BSN FBXO45 JAKMIP2 GOLGB1 KIF3A

4.03e-11963681628671696
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

NEFL TBC1D31 KRT74 PPP1R12A SPTA1 PPFIA1 CNTRL SYNE2 ERC2 GRIA3 MSL1 LMNB2 ACTN2 PLEC BSN GOLGB1 PRPH

1.74e-091442681735575683
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

SPTBN5 NEFL DLG5 SPTA1 SYNE2 LMNB2 PLEC PRPH

3.37e-0918768826460568
Pubmed

Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction.

NEFL PPP1R12A ERC2 ACTN2 PLEC BSN

2.30e-0713168628634551
Pubmed

Synaptic profiles during neurite extension, refinement and retraction in the developing cochlea.

GRIA3 BSN PRPH

3.98e-07868323217150
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

FSIP2 DLG5 DLC1 MYCBP2 PPP1R12A RPS6KA2 PPFIA1 SYNE2 MAD1L1 PLEC GOLGB1

8.51e-07861681136931259
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

UBE4B BTBD7 FBXO28 SLIT1 ERC2 DAAM2 RAB11FIP4 MAP3K4

1.32e-0640768812693553
Pubmed

Adjacent asparagines in the NR2-subunit of the NMDA receptor channel control the voltage-dependent block by extracellular Mg2+.

NEFL GRIA3 ACTN2

3.20e-06156839481670
Pubmed

Peripherin is not a contributing factor to motor neuron disease in a mouse model of amyotrophic lateral sclerosis caused by mutant superoxide dismutase.

NEFL PRPH

3.77e-06268212828939
Pubmed

Peripherin is a subunit of peripheral nerve neurofilaments: implications for differential vulnerability of CNS and peripheral nervous system axons.

NEFL PRPH

3.77e-06268222723690
Pubmed

Deletion of the presynaptic scaffold CAST reduces active zone size in rod photoreceptors and impairs visual processing.

ERC2 BSN

3.77e-06268222933801
Pubmed

A neurotoxic peripherin splice variant in a mouse model of ALS.

NEFL PRPH

3.77e-06268212642616
Pubmed

Late onset of motor neurons in mice overexpressing wild-type peripherin.

NEFL PRPH

3.77e-06268215132161
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

DLG5 TBC1D31 TCHP MYCBP2 RNASEH2A PPP1R12A CEP135 MSL1 KIF3A

4.57e-0664568925281560
Pubmed

mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle docking.

PPFIA1 ERC2 BSN

7.96e-062068323791195
Pubmed

Peripherin-mediated death of motor neurons rescued by overexpression of neurofilament NF-H proteins.

NEFL PRPH

1.13e-05368212641746
Pubmed

Molecular dissection of the photoreceptor ribbon synapse: physical interaction of Bassoon and RIBEYE is essential for the assembly of the ribbon complex.

ERC2 BSN

1.13e-05368215728193
Pubmed

BPAG1 isoform-b: complex distribution pattern in striated and heart muscle and association with plectin and alpha-actinin.

ACTN2 PLEC

1.13e-05368219932097
Pubmed

Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis.

KIF15 MAD1L1

1.13e-05368231710517
Pubmed

M-cadherin distribution in the mouse adult neuromuscular system suggests a role in muscle innervation.

NEFL CDH15

2.25e-0546828921257
Pubmed

Fbxo45-mediated degradation of the tumor-suppressor Par-4 regulates cancer cell survival.

MYCBP2 FBXO45

2.25e-05468224992930
Pubmed

DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal.

NEFL ERC2 ACTN2

2.79e-053068336460641
Pubmed

The synaptic vesicle cycle.

PPFIA1 ERC2 BSN

3.09e-053168315217342
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

NEFL RNF123 UBE4B MYCBP2 ERC2 DAAM2 CERCAM UBA3 RAB11FIP4 PLEC KIF3A

3.72e-051285681135914814
Pubmed

Essential role of KIBRA in co-activator function of dynein light chain 1 in mammalian cells.

DLC1 WWC1

3.75e-05568216684779
Pubmed

Myosin Va binding to neurofilaments is essential for correct myosin Va distribution and transport and neurofilament density.

NEFL PRPH

3.75e-05568212403814
Pubmed

Plectin and IFAP-300K are homologous proteins binding to microtubule-associated proteins 1 and 2 and to the 240-kilodalton subunit of spectrin.

SPTA1 PLEC

3.75e-0556823027087
Pubmed

The intermediate filament protein peripherin is the specific interaction partner of mouse BPAG1-n (dystonin) in neurons.

NEFL PRPH

3.75e-0556829971739
Pubmed

PAM forms an atypical SCF ubiquitin ligase complex that ubiquitinates and degrades NMNAT2.

MYCBP2 FBXO45

3.75e-05568229997255
Pubmed

Distribution of neuronal intermediate filament proteins in the developing mouse olfactory system.

NEFL PRPH

3.75e-0556829819140
Pubmed

Slit1 and Slit2 cooperate to prevent premature midline crossing of retinal axons in the mouse visual system.

NEFL SLIT1

5.62e-05668211804570
Pubmed

Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter release.

ERC2 BSN

5.62e-05668214734538
Pubmed

A protein interaction node at the neurotransmitter release site: domains of Aczonin/Piccolo, Bassoon, CAST, and rim converge on the N-terminal domain of Munc13-1.

ERC2 BSN

5.62e-05668219812333
Pubmed

Samp1 is a component of TAN lines and is required for nuclear movement.

SYNE2 LMNB2

5.62e-05668222349700
Pubmed

TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton.

SYNE2 PLEC

5.62e-05668218827015
Pubmed

Two novel transcripts encoding two Ankyrin repeat containing proteins have preponderant expression during the mouse spermatogenesis.

POTEB2 POTEB

5.62e-05668217171436
Pubmed

The cytoskeleton of the myenteric neurons during murine embryonic life.

NEFL PRPH

7.86e-05768210221457
Pubmed

The E3 ubiquitin ligase protein associated with Myc (Pam) regulates mammalian/mechanistic target of rapamycin complex 1 (mTORC1) signaling in vivo through N- and C-terminal domains.

MYCBP2 FBXO45

7.86e-05768222798074
Pubmed

The cellular function of MASH1 in autonomic neurogenesis.

NEFL PRPH

7.86e-0576828845150
Pubmed

Hey bHLH Proteins Interact with a FBXO45 Containing SCF Ubiquitin Ligase Complex and Induce Its Translocation into the Nucleus.

MYCBP2 FBXO45

7.86e-05768226068074
Pubmed

Interaction between GRIP and liprin-alpha/SYD2 is required for AMPA receptor targeting.

PPFIA1 GRIA3

7.86e-05768211931740
Pubmed

Kif3a regulates planar polarization of auditory hair cells through both ciliary and non-ciliary mechanisms.

SPTA1 KIF3A

7.86e-05768221752934
Pubmed

A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.

DLG5 PPP1R12A PPFIA1 GOLGB1

8.67e-0511868430979931
Pubmed

HENA, heterogeneous network-based data set for Alzheimer's disease.

KXD1 CEP135 ACTN2 KIF3A

9.25e-0512068431413325
Pubmed

Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors.

MYCBP2 FBXO45

1.05e-04868225460509
Pubmed

Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development.

CCNG1 RNASEH2A

1.05e-04868222579044
Pubmed

POTE, a highly homologous gene family located on numerous chromosomes and expressed in prostate, ovary, testis, placenta, and prostate cancer.

POTEB2 POTEB

1.05e-04868212475935
Pubmed

Slit2 and Robo3 modulate the migration of GnRH-secreting neurons.

SLIT1 PRPH

1.05e-04868222912413
Pubmed

Evolutionary and molecular facts link the WWC protein family to Hippo signaling.

DLC1 WWC1

1.05e-04868224682284
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

ARHGAP22 NEFL MYCBP2 CNTRL SLIT1 MAD1L1 ACTN2

1.12e-0456068721653829
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

RNF123 KIF15 UBE4B RNASEH2A PPP1R12A PPFIA1 ANXA6 MAD1L1 PYGL UBA3 PLEC

1.13e-041455681122863883
Pubmed

Two RNase H2 Mutants with Differential rNMP Processing Activity Reveal a Threshold of Ribonucleotide Tolerance for Embryonic Development.

CCNG1 RNASEH2A

1.34e-04968230380406
Pubmed

Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins.

PPFIA1 ERC2

1.34e-04968212923177
Pubmed

Nestin mRNA expression correlates with the central nervous system progenitor cell state in many, but not all, regions of developing central nervous system.

NEFL PRPH

1.34e-0496827720210
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

TBC1D31 TCHP PPFIA1 SYNE2 KIF3A

1.35e-0425168529778605
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

DLG5 KIF15 TCHP RNASEH2A ERC2 BSN GOLGB1

1.51e-0458868738580884
Pubmed

Ephrin-A5/EphA4 signalling controls specific afferent targeting to cochlear hair cells.

GRIA3 PRPH

1.68e-041068223385583
Pubmed

Nesprin 1α2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscle.

SYNE2 LMNB2

1.68e-041068228533284
Pubmed

Identification and validation of novel spinophilin-associated proteins in rodent striatum using an enhanced ex vivo shotgun proteomics approach.

NEFL ACTN2

1.68e-041068220124353
Pubmed

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.

TBC1D31 TCHP CNTRL CEP135

1.97e-0414668421399614
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

NEFL PPP1R12A SPTA1 AMOTL1 GRIA3 PRPH

1.98e-0443068632581705
Pubmed

Fbxo45 inhibits calcium-sensitive proteolysis of N-cadherin and promotes neuronal differentiation.

MYCBP2 FBXO45

2.05e-041168225143387
Pubmed

Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth.

AMOTL1 ACTN2

2.05e-041168228239148
Pubmed

Role of p90 ribosomal S6 kinase-mediated prorenin-converting enzyme in ischemic and diabetic myocardium.

RPS6KA2 ACTN2

2.05e-041168216585392
Pubmed

The terminal nerve plays a prominent role in GnRH-1 neuronal migration independent from proper olfactory and vomeronasal connections to the olfactory bulbs.

SLIT1 PRPH

2.05e-041168228970231
Pubmed

Network organization of the huntingtin proteomic interactome in mammalian brain.

NEFL RPS6KA2 SPTA1 ERC2 PYGL LMNB2 BSN

2.11e-0462168722794259
Pubmed

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.

MYCBP2 CNTRL CEP135 ACTN2 GOLGB1

2.44e-0428568532838362
Pubmed

Expression of Ca2+/calmodulin-dependent protein kinase types II and IV, and reduced DNA synthesis due to the Ca2+/calmodulin-dependent protein kinase inhibitor KN-62 (1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenyl piperazine) in small cell lung carcinoma.

NEFL ACTN2

2.45e-04126828615909
Pubmed

Mammalian E4 is required for cardiac development and maintenance of the nervous system.

UBE4B ACTN2

2.45e-041268216314518
Pubmed

Activation of peripheral NMDA receptors contributes to human pain and rat afferent discharges evoked by injection of glutamate into the masseter muscle.

NEFL ACTN2

2.45e-041268212815021
Pubmed

p63 Transcription Factor Regulates Nuclear Shape and Expression of Nuclear Envelope-Associated Genes in Epidermal Keratinocytes.

SYNE2 PLEC

2.45e-041268228595999
Pubmed

Developmental rearrangements of cortical glutamate-NMDA receptor binding sites in late human gestation.

NEFL ACTN2

2.45e-04126828665664
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

NEFL MYCBP2 ANXA6 SYNE2 PYGL LMNB2 PLEC

2.86e-0465368722586326
Pubmed

LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.

FSIP2 TBC1D31 SPTA1 JAKMIP2

3.36e-0416868430631154
Pubmed

O-linked N-acetylglucosamine proteomics of postsynaptic density preparations using lectin weak affinity chromatography and mass spectrometry.

NEFL BSN

3.38e-041468216452088
Pubmed

Ras-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of Raf.

NEFL ACTN2

3.38e-041468210373510
Pubmed

Calcium channels link the muscle-derived synapse organizer laminin β2 to Bassoon and CAST/Erc2 to organize presynaptic active zones.

ERC2 BSN

3.38e-041468221228161
Pubmed

Next-generation sequencing to generate interactome datasets.

CCNG1 TCHP CCDC146 FBXO28 PPFIA1 MAD1L1 KXD1 DACH1 TFAP4

3.84e-04114768921516116
Pubmed

The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1.

NEFL ACTN2

3.89e-041568214622581
Pubmed

A molecular mechanism underlying the neural-specific defect in torsinA mutant mice.

SYNE2 LMNB2

3.89e-041568220457914
Pubmed

FBXO45-MYCBP2 regulates mitotic cell fate by targeting FBXW7 for degradation.

MYCBP2 FBXO45

3.89e-041568231285543
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

ARHGAP22 NEFL DLC1 FBXO28 PPP1R12A ANXA6 LMNB2 PLEC

4.11e-0491668832203420
Pubmed

Interaction of zonula occludens-1 (ZO-1) with alpha-actinin-4: application of functional proteomics for identification of PDZ domain-associated proteins.

ANXA6 PLEC

4.44e-041668216944923
Pubmed

Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.

MYCBP2 PLEC GOLGB1

4.54e-047668327542412
Pubmed

FBXW7 modulates cellular stress response and metastatic potential through ​HSF1 post-translational modification.

MYCBP2 FBXO45 PRPH

4.90e-047868325720964
Pubmed

Association analysis of 3p21 with Crohn's disease in a New Zealand population.

RNF123 BSN

5.03e-041768220307617
Pubmed

Fbxo45 forms a novel ubiquitin ligase complex and is required for neuronal development.

MYCBP2 FBXO45

5.03e-041768219398581
Pubmed

Pitchfork regulates primary cilia disassembly and left-right asymmetry.

CEP135 KIF3A

5.03e-041768220643351
Pubmed

Proteomic analysis reveals novel ligands and substrates for LNX1 E3 ubiquitin ligase.

MYCBP2 PPFIA1 ERC2

5.08e-047968329121065
Pubmed

Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrPC) in Alzheimer's disease.

NEFL ANXA6 UBA3 LMNB2 BSN

5.53e-0434168529791485
Pubmed

Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.

SPTBN5 SPTA1

5.65e-041868212119179
Pubmed

A pilot proteomic study of amyloid precursor interactors in Alzheimer's disease.

NEFL SPTA1

5.65e-041868216049941
Pubmed

Evidence for distinct functions for human DNA repair factors hHR23A and hHR23B.

SZT2 UBA3

5.65e-041868216712842
Pubmed

Arhgap22 Disruption Leads to RAC1 Hyperactivity Affecting Hippocampal Glutamatergic Synapses and Cognition in Mice.

ARHGAP22 GRIA3

5.65e-041868234455539
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

UBE4B TCHP MYCBP2 PPP1R12A RPS6KA2 ANXA6 MAD1L1 TFAP4 GOLGB1 CDH15

6.07e-041489681028611215
Pubmed

Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.

LMNB2 PLEC BSN

6.08e-048468319165527
Pubmed

A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse.

BICDL1 TCHP ERC2

6.30e-048568323055939
Pubmed

Proteomic analysis of NMDA receptor-adhesion protein signaling complexes.

SPTA1 ACTN2 BSN

6.51e-048668310862698
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

MYCBP2 SYNE2 SLIT1 FBXO45 KIF3A

6.89e-0435868532460013
Pubmed

Disruption of the mouse MRF4 gene identifies multiple waves of myogenesis in the myotome.

ACTN2 CDH15

7.00e-04206827588068
InteractionKRT19 interactions

DLG5 RNF123 TBC1D31 KIF15 TCHP CCDC146 KRT74 AMOTL1 PLEC PRPH

3.49e-082826810int:KRT19
InteractionKRT18 interactions

NEFL DLG5 TBC1D31 KIF15 TCHP CCDC146 KRT74 PPFIA1 PLEC PRPH

1.34e-064196810int:KRT18
InteractionGAN interactions

SPTBN5 NEFL DLG5 SPTA1 SYNE2 LMNB2 PLEC PRPH

2.13e-06253688int:GAN
InteractionALOX5 interactions

RNF123 C10orf67 RPS6KA2 AMOTL1 MAD1L1

5.07e-0674685int:ALOX5
InteractionKIF7 interactions

TBC1D31 PPFIA1 CNTRL CEP135 MAP3K4 PRPH

9.86e-06146686int:KIF7
InteractionAMOT interactions

DLG5 RNF123 KIF15 TCHP PPFIA1 AMOTL1 LMNB2 WWC1

9.96e-06312688int:AMOT
InteractionGRIP2 interactions

PPFIA1 ERC2 GRIA3

1.30e-0514683int:GRIP2
InteractionIFFO1 interactions

TCHP AMOTL1 CEP135 PRPH

3.30e-0554684int:IFFO1
InteractionKRT24 interactions

TCHP CCDC146 KRT74 PRPH

3.30e-0554684int:KRT24
InteractionCDC14A interactions

NEFL TBC1D31 MYCBP2 PPFIA1 CEP135

3.66e-05111685int:CDC14A
InteractionTNIK interactions

MYCBP2 SYNE2 KXD1 ERC2 GRIA3 LMNB2 FBXO45 WWC1

4.17e-05381688int:TNIK
InteractionPPP1R9B interactions

NEFL MYCBP2 PPP1R12A RPS6KA2 KXD1 ERC2 ACTN2 PLEC BSN KIF3A

4.46e-056266810int:PPP1R9B
InteractionKRT16 interactions

TCHP CCDC146 KRT74 AMOTL1 PLEC PRPH

5.35e-05197686int:KRT16
InteractionSYNC interactions

NEFL RNF123 KIF15 PRPH

7.74e-0567684int:SYNC
InteractionINSL6 interactions

RNF123 MYCBP2 FBXO45

8.01e-0525683int:INSL6
InteractionRAB11FIP4 interactions

FBXO28 KXD1 RAB11FIP4

8.01e-0525683int:RAB11FIP4
InteractionNDC80 interactions

DLG5 TBC1D31 KIF15 TCHP SYNE2 MAD1L1 CEP135

8.61e-05312687int:NDC80
InteractionKRT8 interactions

NEFL DLG5 TBC1D31 KIF15 TCHP KRT74 PLEC PRPH

1.16e-04441688int:KRT8
InteractionMED4 interactions

DLG5 TBC1D31 TCHP MYCBP2 CCDC146 CNTRL CEP135 KIF3A

1.33e-04450688int:MED4
InteractionARHGEF25 interactions

NEFL PPP1R12A PLEC

1.70e-0432683int:ARHGEF25
InteractionGRIN1 interactions

NEFL RNF123 SPTA1 ACTN2 BSN

1.73e-04154685int:GRIN1
InteractionODF2 interactions

DLG5 TBC1D31 TCHP CNTRL CEP135

1.95e-04158685int:ODF2
InteractionKRT26 interactions

RNF123 CCDC146 KRT74

2.23e-0435683int:KRT26
InteractionCNTROB interactions

TCHP CEP135 MSL1 BSN MAP3K4

2.45e-04166685int:CNTROB
InteractionPPFIA2 interactions

RNF123 PPFIA1 ERC2

2.63e-0437683int:PPFIA2
InteractionMPHOSPH9 interactions

CNTRL KXD1 CEP135 PRPH

3.00e-0495684int:MPHOSPH9
InteractionHDAC1 interactions

RNF123 KIF15 MYCBP2 PPFIA1 SYNE2 MAD1L1 CEP135 DACH1 JDP2 PLEC TFAP4 GOLGB1

3.00e-0411086812int:HDAC1
InteractionCLEC11A interactions

MYCBP2 FBXO28 MAD1L1 FBXO45

3.12e-0496684int:CLEC11A
Cytoband13q22

MYCBP2 DACH1

1.18e-041168213q22
CytobandEnsembl 112 genes in cytogenetic band chr5q34

CCNG1 WWC1

1.71e-0341682chr5q34
GeneFamilyEF-hand domain containing|Spectrins

SPTBN5 SPTA1

1.26e-0474521113
GeneFamilyAnkyrin repeat domain containing|POTE ankyrin domain containing

POTEB2 POTEB

4.64e-0413452685
GeneFamilyCyclins|F-boxes other

FBXO28 FBXO45

4.23e-0339452560
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF15 KIF3A

5.85e-0346452622
GeneFamilyRho GTPase activating proteins|BCH domain containing

ARHGAP22 DLC1

6.88e-0350452721
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

NEFL PPP1R12A WWC1

1.03e-02181453694
GeneFamilyAnkyrin repeat domain containing

PPP1R12A POTEB2 POTEB

2.22e-02242453403
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

TBC1D31 DLC1 MYCBP2 PPP1R12A RPS6KA2 PPFIA1 SYNE2 MAD1L1 CEP135 WWC1 MAP3K4

1.18e-058566811M4500
CoexpressionGSE3982_NKCELL_VS_TH2_UP

SPTBN5 UBE4B SYNE2 LTBP2 ACTN2 BSN

1.24e-05197686M5596
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SPTBN5 DLC1 AMOTL1 DACH1 ACTN2

5.89e-06168685217770a94ace446cdfc7687b459dece707576e76
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_ETV4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SPTBN5 ARHGAP22 DLC1 DACH1 ACTN2

6.07e-06169685716e9d4c5fb99c56b76afaa5ed90bfa859fde802
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCBP2 ANXA6 DAAM2 ACTN2 RAB11FIP4

7.39e-06176685feafc757e7aa4f17128ff34886beb2fd3461c9ea
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-8|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

ANXA6 CERCAM LTBP2 ACTN2 CDH15

1.18e-0519468555b97095a7a17a312c616703d291738a0f806339
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / Treatment groups by lineage, cell group, cell type

SYNE2 MATN4 GOLGB1 WWC1 KIF3A

1.27e-051976851a1bee8da6e04b65935c40373eaee4d6c046d9a1
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

MYCBP2 CCDC146 CNTRL SYNE2 GOLGB1

1.31e-0519868576d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW09-Stem_cells-Stem_cells|GW09 / Sample Type, Dataset, Time_group, and Cell type.

KIF15 RNASEH2A SYNE2 CEP135 DACH1

1.37e-05200685c00cc0b91baa37828895d9d6b8acbc6aa503215a
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW09-Stem_cells|GW09 / Sample Type, Dataset, Time_group, and Cell type.

KIF15 RNASEH2A SYNE2 CEP135 DACH1

1.37e-052006859e1b62a703fb7d413ce580448a1df5127c28e8a7
ToppCellLymphoid-Lymphoid-NK_cells|Lymphoid / shred on cell class and cell subclass (v4)

AMOTL1 HEATR9 GRIA3 KIF3A

7.77e-05148684d51a4b654a88d58dcdf29c2bc362c0cc1c40723a
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TCHP C10orf67 MATN4 JAKMIP2

9.53e-05156684abea3c183d32062b009a79a2bdf861021989c7ef
ToppCellSevere-B_naive-5|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FSIP2 ARHGAP22 PYGL RAB11FIP4

9.77e-05157684a57ee4a6febdff3ee3d1645836695e6e7c055cf8
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B1|367C / Donor, Lineage, Cell class and subclass (all cells)

RNF123 KRT74 FBXO28 SYNE2

1.08e-04161684f470b662566131dfe69a2fd01186ac8491196396
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DLC1 DAAM2 MATN4 JAKMIP2

1.10e-04162684d28b2ea1d2c8f3c6a107991573471b6d0c49c4ae
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DLC1 DAAM2 MATN4 JAKMIP2

1.10e-041626845bbd7130d4dad9035e73a439dda568195c136f31
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DLC1 DAAM2 MATN4 JAKMIP2

1.10e-04162684eed223e61c8162a2fe004ab4e09de5e037be7553
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DLC1 DAAM2 MATN4 JAKMIP2

1.10e-04162684e35ddce830e20ebeac1a2c405293fc4a5323dd4a
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FSIP2 C10orf67 MATN4 JAKMIP2

1.18e-04165684436ce4bc75e1ba4351c439ccad19f84ad5bcb92f
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FSIP2 C10orf67 MATN4 JAKMIP2

1.18e-04165684242bdb7654f415391fb8e9bdc06412c7eee9c97e
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SPTBN5 DLC1 AMOTL1 DACH1

1.21e-04166684739dfbe927f409821ff23aca6e47ebe78f57e859
ToppCellICU-NoSEP-Lymphocyte-T_NK-NK_CD56bright|ICU-NoSEP / Disease, Lineage and Cell Type

NBPF3 DLG5 TBC1D31 DACH1

1.24e-04167684f4f188a8efca8cdd0ecfb857fe4538c10847eadd
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BICDL1 RAB11FIP4 CDH15 PRPH

1.30e-04169684606aa4ff25380d9470ec116ca86cd20f8b19587a
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NBPF3 RPS6KA2 GRIA3 DAAM2

1.30e-04169684c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BICDL1 RAB11FIP4 CDH15 PRPH

1.30e-04169684052aae2af5446a0de071d5dda5381b0b9a0ed54d
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SPTBN5 DLC1 DACH1 ACTN2

1.33e-0417068484d49a1f2989d98bd0acf9ec2d59f1042fc0f55b
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEFL RPS6KA2 PYGL RAB11FIP4

1.33e-0417068417bd7fd25a2657cb536ad47e294332920f759e95
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DLC1 AMOTL1 DACH1 ACTN2

1.39e-04172684cecfe5cf20f317ea01b4604789e07a14481c4cd6
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP22 DLC1 DACH1 ACTN2

1.42e-0417368495c723b09254ae7131fe5ba0841472502e83269b
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS6KA2 SYNE2 DACH1 MSL1

1.48e-04175684cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TCP11 PPP1R12A ANXA6 RAB11FIP4

1.55e-0417768444c38e572a9e9678c2dbb3e8b4748e7e28d404b7
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

DLC1 DACH1 DAAM2 LTBP2

1.58e-04178684185b44700f06ec58b3c09c80520502166c965fd6
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BTBD7 CNTRL SYNE2 DACH1

1.58e-0417868401dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

NEFL BICDL1 SYNE2 MAP3K4

1.65e-04180684d9dae9db8e17f6990032ee6cfa8393fae4768ca5
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BTN3A3 FBXO28 ANXA6 UBA3

1.72e-04182684dfde2d9950f445c6c936ac828f7210de87bb45ec
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BTN3A3 FBXO28 ANXA6 UBA3

1.72e-0418268452274af3136d4fd4a495f5882618444661421f0f
ToppCelldroplet-Marrow-nan-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF15 ANXA6 GRIA3 PLEC

1.72e-04182684bc8d621be57f76d718d9b0f11e023b0f4dcb668d
ToppCellThalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6|Thalamus / BrainAtlas - Mouse McCarroll V32

HEATR9 ACTN2 PRPH

1.75e-04716837623b110bc3db0f5b99803c8fbb881ae8846b817
ToppCellInfluenza-Influenza_Severe-Myeloid-Neutrophil|Influenza_Severe / Disease, condition lineage and cell class

DAAM2 PYGL MSL1 DCAF4L1

1.87e-041866841dfcec9196d4db76fba3abc74e85885b1fb98b87
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

NEFL BICDL1 SYNE2 MAP3K4

1.91e-04187684e1d6c1194476cf26969e405b0951796fed519f44
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP22 BICDL1 SYNE2 WWC1

1.91e-04187684c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYCBP2 AMOTL1 LTBP2 GOLGB1

2.03e-04190684d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellCOVID-19-Heart-EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

DLC1 SYNE2 DACH1 DAAM2

2.03e-04190684a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

RNF123 KRT74 FBXO28 CERCAM

2.07e-0419168439ef8e1d7cc3ebb11717e8a55501515e3b72b177
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TBC1D31 KIF15 CEP135 LMNB2

2.07e-041916840ba5b112a82e489f5a21966f78a403a7436ce73b
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MYCBP2 ERC2 BSN KIF3A

2.07e-041916845d24022cec293bc8d9e978ae99a109e660bb8f83
ToppCellEntopeduncular-Neuronal-Inhibitory|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MYCBP2 ERC2 BSN KIF3A

2.07e-0419168473dae4cdea86aec62393ad7303dc7375a6b3fc86
ToppCellP07-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ARHGAP22 DAAM2 MATN4 WWC1

2.07e-041916840f360766490bef3495c42f6421b22a988cfc68fb
ToppCell(210)_NKT_cell|World / immune cells in Peripheral Blood (logTPM normalization)

DLG5 ANXA6 SYNE2 HEATR9

2.11e-0419268408dc0c019c594da7b9944db8fd706aa7780e6ae9
ToppCellEntopeduncular-Neuronal|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MYCBP2 ERC2 BSN KIF3A

2.11e-041926844c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCell(21)_NKT_cell|World / immune cells in Peripheral Blood (logTPM normalization)

DLG5 ANXA6 SYNE2 HEATR9

2.11e-04192684b0a573ddde2978485a857b8261ee1ee5ef68ecef
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DLC1 SLIT1 DACH1 DAAM2

2.16e-041936849f69edc97b868d23998abc98928a2e89a885ef8a
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_NK-natural_killer_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ANXA6 SYNE2 CERCAM JAKMIP2

2.20e-04194684a3a81638b55cb5fc08fe83c8b88f68d49b87e6cb
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DLC1 SLIT1 DACH1 DAAM2

2.20e-0419468471d3c7448b1734de54187f902f65649f9283bd4c
ToppCellLeuk-UTI-Lymphocyte-T_NK-NK|Leuk-UTI / Disease, Lineage and Cell Type

TBC1D31 SYNE2 CERCAM JAKMIP2

2.20e-0419468436afc4e48d267be3b8aa1e33fad043bcd54c6bc5
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_NK-natural_killer_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ANXA6 SYNE2 CERCAM JAKMIP2

2.20e-041946840abca32c3547a45cebab0bd69c1f7a0002deaa80
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BTN3A3 MYCBP2 ANXA6 CNTRL

2.24e-041956844b9663509cc5e3f409f6d0d37640cb301a827d98
ToppCellproximal-Hematologic-Natural_Killer_T-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RAB11FIP4 FBXO45 JAKMIP2 TFAP4

2.24e-041956844d7c2c4d0130c2d46877ff6dd4584525d8f74daf
ToppCellproximal-3-Hematologic-Natural_Killer_T|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RAB11FIP4 FBXO45 JAKMIP2 TFAP4

2.24e-0419568493093545bb23d2619ace029a52cffa1f673a0c2a
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCBP2 RPS6KA2 ERC2 GOLGB1

2.24e-041956843e519cffa6144a62b06124642a14c9ff39b76554
ToppCellproximal-Hematologic-Natural_Killer_T|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RAB11FIP4 FBXO45 JAKMIP2 TFAP4

2.24e-041956843944e4800f5d904d4efa401ce8913ec0e0781211
ToppCellsevere-Myeloid-Immature_Neutrophils_1|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

RPS6KA2 DACH1 JDP2 PYGL

2.24e-04195684becad890a420267ca41e98e61a8da343b51e1945
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYCBP2 RPS6KA2 ERC2 GOLGB1

2.24e-041956847796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellhealthy_donor-Lymphocytic-T_cell-CD8+_Memory_T_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

BTN3A3 ANXA6 SYNE2 JAKMIP2

2.29e-04196684af00c31612e4fe068e5fccae05368edba46bbd20
ToppCellEpithelial-A_(AT1)|World / shred on cell class and cell subclass (v4)

ARHGAP22 DAAM2 MATN4 WWC1

2.29e-04196684484bbc6b1f58bc260964babb949d14f5df101393
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BTN3A3 MYCBP2 ANXA6 CNTRL

2.29e-04196684c9fb81a0578db6d278b8582d7b3add6c407e6dcf
ToppCellCOVID-19_Severe-Neu_2|World / 5 Neutrophil clusters in COVID-19 patients

RPS6KA2 DACH1 PYGL PLEC

2.29e-0419668416359a56297f0558fc93fa52563cce0c53def167
ToppCellCOVID-19_Severe-CD8+_Tem|COVID-19_Severe / disease group, cell group and cell class

BICDL1 ANXA6 SYNE2 JAKMIP2

2.29e-041966841bc1ec3351319c5d2daa0808cf161a7327e1758e
ToppCellCOVID-19_Severe-Neu_2|COVID-19_Severe / 5 Neutrophil clusters in COVID-19 patients

RPS6KA2 DACH1 PYGL PLEC

2.33e-04197684945f19475905cdedf232315eea1076ca0b753b67
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

TBC1D31 KIF15 CNTRL CEP135

2.38e-04198684629d674a9c9108c1acb3f7af57bbdbf34bb0528e
ToppCellmetastatic_Brain-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

DLC1 PPP1R12A SYNE2 DAAM2

2.38e-0419868486a4c8e859ce11a95875f8844963baeb1ba898ec
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ERC2 DAAM2 ACTN2 PRPH

2.38e-041986841e1ea54f0c234f3b6d29064c4881d8a0c0949a75
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PPP1R12A ANXA6 AMOTL1 LTBP2

2.38e-04198684c9c96066c7fa897b583657f0b77ea093920ae9ba
ToppCellTracheal-10x3prime_v2-Stromal-Fibroblastic-Fibro_myofibroblast|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

GRIA3 DAAM2 LTBP2 CDH15

2.38e-0419868408d393853e195a7eacace454153e425a273e2d23
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

CCDC146 CNTRL SYNE2 GOLGB1

2.42e-0419968461b1ed2db71b96157b92b7535d1955a4033098da
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SYNE2 CERCAM GOLGB1 WWC1

2.42e-04199684d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

CCDC146 CNTRL SYNE2 GOLGB1

2.42e-04199684fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

KIF15 RNASEH2A CEP135 LMNB2

2.42e-04199684d8f904f531bfe091b7d8caaa147ea4a03d627995
ToppCellLPS_IL1RA-Endothelial-Endothelial-FOXM1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

KIF15 CNTRL SYNE2 LMNB2

2.42e-04199684be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DLC1 RPS6KA2 SYNE2 DACH1

2.47e-0420068472ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellStriatum-Neuronal|Striatum / BrainAtlas - Mouse McCarroll V32

MYCBP2 ERC2 BSN KIF3A

2.47e-04200684c888fd487990cad482a4ca47601cdebc0ca3f3ce
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.

NEFL SLIT1 ACTN2 PLEC

2.47e-0420068461d7dd0a78942b069c3f5e75044368dc00e6e8e6
ToppCellCOVID-19-COVID-19_Severe-Myeloid-immature_Neutrophil|COVID-19_Severe / Disease, condition lineage and cell class

DACH1 JDP2 PYGL MATN4

2.47e-04200684cbe667eda1af222467df8bfa157aa22df488f133
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells-Neuroepithelial_cell|2m / Sample Type, Dataset, Time_group, and Cell type.

KIF15 CNTRL SYNE2 CEP135

2.47e-042006840d9b8d51a7630e70e60c76c763ff82df4c559152
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DLC1 RPS6KA2 SYNE2 DACH1

2.47e-042006845c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SYNE2 CERCAM GOLGB1 WWC1

2.47e-04200684ddfb1f006365bf16203ee49f20200f68220cc288
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells|2m / Sample Type, Dataset, Time_group, and Cell type.

KIF15 CNTRL SYNE2 CEP135

2.47e-042006840675f580ccef705875854247bbfd4ee2bcf126a1
ToppCellLPS_only-Endothelial|LPS_only / Treatment groups by lineage, cell group, cell type

DLC1 RPS6KA2 SYNE2 DACH1

2.47e-0420068481e76508c9050d533853d5fd2f3097b27613d836
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial-Astrocyte|GW10 / Sample Type, Dataset, Time_group, and Cell type.

CCNG1 ANXA6 PRMT7 FBXO45

2.47e-0420068498a994692440cb4f505b050276f0c8022c814a21
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SYNE2 CERCAM GOLGB1 WWC1

2.47e-042006848683445ad5b70748c4a1f12eb77d47623085147e
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

DLG5 BTN3A3 SYNE2 JAKMIP2

2.47e-042006842281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellNeuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_1(EFTUD1P1)---L5-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

SPTBN5 DLC1 AMOTL1 DACH1

2.47e-04200684046a3a4d7e4d84ee4252a695ffd4a6aee8b77070
ToppCellNeuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_1(EFTUD1P1)-|Neuronal / cells hierarchy compared to all cells using T-Statistic

SPTBN5 DLC1 AMOTL1 DACH1

2.47e-04200684893cc7f6b9794da90aa0c9d721b8647dc97201cd
ToppCellNeuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_1(EFTUD1P1)|Neuronal / cells hierarchy compared to all cells using T-Statistic

SPTBN5 DLC1 AMOTL1 DACH1

2.47e-042006843d677f13e429abc805a52ec2b8f36c703f511569
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial|GW10 / Sample Type, Dataset, Time_group, and Cell type.

CCNG1 ANXA6 PRMT7 FBXO45

2.47e-04200684ef222dc4a205d670172dae74990bdb952ac92e5b
ToppCellSepsis-Leuk-UTI-Lymphocyte-T/NK-NK|Leuk-UTI / Disease, condition lineage and cell class

TBC1D31 SYNE2 CERCAM JAKMIP2

2.47e-04200684bb37fed4872e71f413ae7c4aa12586fa31075334
ToppCellFibroblast|World / shred by cell class for parenchyma

ANXA6 SLIT1 CERCAM LTBP2

2.47e-04200684dec9ce1bc2571197003596f32e5f742ede72aa79
ToppCellSepsis-ICU-NoSEP-Lymphocyte-T/NK-NK_CD56bright|ICU-NoSEP / Disease, condition lineage and cell class

NBPF3 DLG5 TBC1D31 DACH1

2.47e-04200684c2df917900872453ea17a39928e39d071a6d3339
ToppCellNeuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_1(EFTUD1P1)--|Neuronal / cells hierarchy compared to all cells using T-Statistic

SPTBN5 DLC1 AMOTL1 DACH1

2.47e-0420068412518f4a8d01fc66b72878cdf0ba124b37cff3d8
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-GABAergic_neurons|GW23 / Sample Type, Dataset, Time_group, and Cell type.

MYCBP2 RPS6KA2 SLIT1 JAKMIP2

2.47e-04200684c6bbd33bca86ac7a76a7ba704b3e141237d04549
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / Treatment groups by lineage, cell group, cell type

DLC1 RPS6KA2 SYNE2 DACH1

2.47e-042006844bb609a284d4e6066f17470a1736076aa4a1f84c
Diseaseplasminogen activator inhibitor 1 measurement

KRT74 RPS6KA2 MAD1L1 MAP3K4

6.64e-0654664EFO_0004792
Diseasethioredoxin domain-containing protein 12 measurement

RNF123 ERC2 BSN

9.22e-0539663EFO_0008298
Diseasetumor necrosis factor ligand superfamily member 6, soluble form measurement

RNF123 BSN

1.03e-047662EFO_0020797
DiseasePR interval

DLC1 MYCBP2 PPFIA1 SYNE2 LMNB2 PLEC TFAP4

1.19e-04495667EFO_0004462
Diseasesexual dimorphism measurement

SPTBN5 TCP11 SLIT1 ERC2 CATSPER3 MSL1 LTBP2 RAB11FIP4 PLEC BSN

1.65e-0411066610EFO_0021796
Diseasemacrovascular complications of diabetes

CCDC146 RPS6KA2

2.19e-0410662EFO_0010977
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

SYNE2 LMNB2

3.21e-0412662DOID:11726 (implicated_via_orthology)
Diseasetriacylglycerol 46:0 measurement

ERC2 JAKMIP2

5.08e-0415662EFO_0010400
DiseaseFebrile seizure (within the age range of 3 months to 6 years)

ERC2 BSN

7.37e-0418662HP_0002373
Diseasesphingomyelin 22:0 measurement

TCHP ACTN2

9.12e-0420662EFO_0010395
Diseasetriacylglycerol 48:2 measurement

ERC2 JAKMIP2

1.11e-0322662EFO_0010405
DiseaseFEV/FEC ratio

SPTBN5 DLC1 KIF15 TCP11 SYNE2 ERC2 MSL1 LTBP2 TFAP4

1.59e-031228669EFO_0004713
Diseasebipolar disorder

DLC1 KIF15 RPS6KA2 SLIT1 MAD1L1 PLEC

1.83e-03577666MONDO_0004985

Protein segments in the cluster

PeptideGeneStartEntry
LERDKREIERMTAES

CNTRL

1761

Q7Z7A1
REALERMEKLLETID

ACTN2

501

P35609
EKIALSRETEREREM

BTN3A3

276

O00478
TEDSIRKFERELMLE

CATSPER3

271

Q86XQ3
FLRLMEDSDRETLRL

BRICD5

126

Q6PL45
REKEERILALEADMT

AMOTL1

671

Q8IY63
SVEMTALKEERDRLR

BICDL1

441

Q6ZP65
KMDFLRERELRETLE

DACH1

651

Q9UI36
RSELDMLDIREIFRT

ANXA6

281

P08133
RMSDRLEDTSLRLKD

RAB11FIP4

456

Q86YS3
MLREEIAKLRLELDE

POTEB2

491

H3BUK9
RMTARLRDFEVKDLL

CCNG1

46

P51959
MELVSRLERKERECE

DAAM2

456

Q86T65
ESERDIRRLMDEIKA

JAKMIP2

201

Q96AA8
FSRREDMERAIRDLV

MATN4

91

O95460
ERSRLEEEKRMLEAQ

MAD1L1

511

Q9Y6D9
TLRLRILSEDIERDM

KIF15

1046

Q9NS87
EDERFRLLLRMLEKR

WWC1

1036

Q8IX03
SAAREELKEARMRLE

LMNB2

301

Q03252
RTEFLQRESERLELM

JDP2

96

Q8WYK2
LREEEELLREQEKMR

BSN

1046

Q9UPA5
MEAERLRLLEEEAKL

DCAF4L1

1

Q3SXM0
LLLTRMAEDVKREER

FSIP2

261

Q5CZC0
IEEMDRRQEKRYLID

GRIA3

206

P42263
VEMKRDLDSIFRRIR

KXD1

71

Q9BQD3
RLELERKIESLMDEI

PRPH

211

P41219
DQTRLKDDVDMLRRE

DLG5

236

Q8TDM6
VSMLEERDRLLDTLR

PPFIA1

41

Q13136
ELFLLRKTLEEMELR

ERC2

276

O15083
LLEESNMELEERRKR

KIF3A

496

Q9Y496
KSERDTLLARIERME

MSL1

251

Q68DK7
DLIKSMLRDERLLTE

NBPF3

121

Q9H094
MLRDERLLTEEKLAE

NBPF3

126

Q9H094
ITRERDELQRMLERF

CEP135

501

Q66GS9
SDLRRIMAEKEALRE

CEP135

576

Q66GS9
DDMIKRALDFRESRE

PRMT7

546

Q9NVM4
RVILDMEDKTLAFER

FBXO45

231

P0C2W1
TDLREEIKVMERFRL

CENPJ

1036

Q9HC77
RLAELERKLREVMES

FBXO28

316

Q9NVF7
RRDLDMEELREILSS

BTBD7

501

Q9P203
DIRLSMRKAEEEELA

LTBP2

736

Q14767
RLERLMEDVEAEKLS

CERCAM

426

Q5T4B2
LNAMLDREKTDRFRL

CDH15

106

P55291
MLRKDLEIAAEFRLS

MAP3K4

821

Q9Y6R4
QFLEIKMAERRELER

SZT2

2796

Q5T011
ELLRKAEETRREMLL

TBC1D31

731

Q96DN5
LLESERERLFAKMED

RNASEH2A

71

O75792
RDTLKERERELQMTL

SYNE2

1196

Q8WXH0
MLREEIAKLRLELDE

POTEB

491

A0A0A6YYL3
ELYEDVRRKALMRLE

MYCBP2

4496

O75592
KEIREDRDRARLDSM

DLC1

341

Q96QB1
RLERELEAMEKEVAR

SPTBN5

3256

Q9NRC6
LRKRMSRLEEELDQE

ARHGAP22

631

Q7Z5H3
EKERDFRNLRKMELL

CCDC146

356

Q8IYE0
TIQKLMDSRDRLREE

C10orf67

301

Q8IYJ2
RRRIEELLAEKMAVD

UBA3

11

Q8TBC4
RLRIEIEEALDMDLL

TCP11

131

Q8WWU5
EMKEETAEERLRRRA

RNF123

471

Q5XPI4
MEELSADEIRRRRLA

UBE4B

1

O95155
LYDQREEREAEKMLR

HEATR9

86

A2RTY3
LERLEEERKQMEAFR

TCHP

251

Q9BT92
LLEREMLAREDALKD

SPTA1

1651

P02549
ERDLDKADSMIRLLF

PLEC

576

Q15149
ERGAFDDMKELERLR

SLIT1

101

O75093
KDVDRLRRMSLIEEE

PYGL

421

P06737
EKAEDLRREMIELRQ

TFAP4

146

Q01664
EERDKLITEMDRSLL

GOLGB1

1546

Q14789
RLDSELRSMRDLVED

KRT74

211

Q7RTS7
RDRVRSKMERDILAE

RPS6KA2

101

Q15349
IEAARKEEERIMLRD

PPP1R12A

166

O14974
QERFADRSLLEMEKR

PPP1R12A

971

O14974
DRSLLEMEKRERRAL

PPP1R12A

976

O14974
RAELEKRIDSLMDEI

NEFL

206

P07196