Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent

HSPG2 FRAS1 CILP MUC17 LAMA3 LAMC2 SPOCK2 LTBP1 MUC2

1.28e-08188679GO:0005201
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

STAB2 LRP1B STAB1

1.96e-0516673GO:0005041
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

STAB2 LRP1B STAB1

4.60e-0521673GO:0030228
GeneOntologyMolecularFunctioncalcium ion binding

HSPG2 EYS STAB2 MEGF6 SPOCK2 LTBP1 LRP1B NOTCH2 EGFL6 STAB1

1.86e-047496710GO:0005509
GeneOntologyMolecularFunctiontumor necrosis factor receptor activity

TNFRSF19 TNFRSF1B

7.16e-0412672GO:0005031
GeneOntologyBiologicalProcessregulation of cell motility

SEMA6B PCSK5 ERBB4 LDB1 IGFBP5 NEXMIF WNT7A MAZ WNT11 CGA LAMA3 LAMC2 SPOCK2 RFFL MUC2 S1PR1

3.00e-0612806816GO:2000145
GeneOntologyBiologicalProcessregulation of locomotion

SEMA6B PCSK5 ERBB4 LDB1 IGFBP5 NEXMIF WNT7A MAZ WNT11 CGA LAMA3 LAMC2 SPOCK2 RFFL MUC2 S1PR1

4.77e-0613276816GO:0040012
GeneOntologyBiologicalProcessregulation of cell migration

SEMA6B PCSK5 ERBB4 LDB1 IGFBP5 NEXMIF WNT7A MAZ WNT11 CGA LAMA3 LAMC2 RFFL MUC2 S1PR1

7.28e-0612116815GO:0030334
GeneOntologyBiologicalProcessanimal organ morphogenesis

HSPG2 FRAS1 ERBB4 IGFBP5 WNT7A WNT11 LAMA3 LAMC2 LHX8 USH2A S1PR1 NOTCH2 AGTPBP1 RHO PML

1.27e-0512696815GO:0009887
GeneOntologyBiologicalProcessheart development

PROK2 PCSK5 SMYD4 HSPG2 ERBB4 WNT11 LTBP1 TNFRSF1B S1PR1 NOTCH2 PDLIM4

3.44e-057576811GO:0007507
GeneOntologyBiologicalProcesscirculatory system development

PROK2 PCSK5 SMYD4 HSPG2 ERBB4 STAB2 WNT7A WNT11 LTBP1 TNFRSF1B S1PR1 NOTCH2 PML PDLIM4 STAB1

5.65e-0514426815GO:0072359
GeneOntologyBiologicalProcesspositive regulation of cell motility

SEMA6B PCSK5 ERBB4 IGFBP5 WNT7A MAZ CGA LAMC2 SPOCK2 S1PR1

1.25e-047256810GO:2000147
GeneOntologyBiologicalProcesspositive regulation of locomotion

SEMA6B PCSK5 ERBB4 IGFBP5 WNT7A MAZ CGA LAMC2 SPOCK2 S1PR1

1.51e-047426810GO:0040017
GeneOntologyBiologicalProcesscell differentiation in hindbrain

LDB1 WNT7A AGTPBP1

1.59e-0432683GO:0021533
GeneOntologyBiologicalProcesscerebellar cortex formation

LDB1 WNT7A AGTPBP1

1.91e-0434683GO:0021697
GeneOntologyBiologicalProcessblood vessel development

PROK2 PCSK5 HSPG2 STAB2 WNT7A WNT11 LTBP1 S1PR1 NOTCH2 PML STAB1

2.12e-049296811GO:0001568
GeneOntologyBiologicalProcesspositive regulation of apoptotic process involved in morphogenesis

TNFRSF1B PML

2.23e-047682GO:1902339
GeneOntologyBiologicalProcesspositive regulation of apoptotic process involved in development

TNFRSF1B PML

2.96e-048682GO:1904747
GeneOntologyBiologicalProcessvasculature development

PROK2 PCSK5 HSPG2 STAB2 WNT7A WNT11 LTBP1 S1PR1 NOTCH2 PML STAB1

3.05e-049696811GO:0001944
GeneOntologyCellularComponentextracellular matrix

HSPG2 FRAS1 EYS MEGF6 CILP LRRC3B MUC17 WNT7A WNT11 LAMA3 LAMC2 SPOCK2 LTBP1 LINGO2 MUC2 USH2A EGFL6

2.29e-116566817GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

HSPG2 FRAS1 EYS MEGF6 CILP LRRC3B MUC17 WNT7A WNT11 LAMA3 LAMC2 SPOCK2 LTBP1 LINGO2 MUC2 USH2A EGFL6

2.40e-116586817GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

HSPG2 FRAS1 EYS MEGF6 CILP MUC17 LAMA3 LAMC2 SPOCK2 LTBP1 MUC2 USH2A EGFL6

1.36e-085306813GO:0062023
GeneOntologyCellularComponentGolgi lumen

PCSK5 HSPG2 MUC17 WNT7A CGA MUC2

1.47e-06109686GO:0005796
GeneOntologyCellularComponentbasement membrane

HSPG2 FRAS1 LAMA3 LAMC2 USH2A EGFL6

2.84e-06122686GO:0005604
GeneOntologyCellularComponentlaminin-5 complex

LAMA3 LAMC2

6.23e-054682GO:0005610
GeneOntologyCellularComponentlaminin complex

LAMA3 LAMC2

4.61e-0410682GO:0043256
DomainGrowth_fac_rcpt_

PCSK5 HSPG2 FRAS1 EYS ERBB4 STAB2 IGFBP5 MEGF6 LAMA3 LAMC2 LTBP1 LRP1B NOTCH2 EGFL6 STAB1

8.06e-181566715IPR009030
DomainEGF

PCSK5 HSPG2 FRAS1 EYS STAB2 MEGF6 MUC17 LAMA3 LAMC2 LTBP1 LRP1B VWDE ADAM28 NOTCH2 EGFL6 STAB1

1.50e-162356716SM00181
DomainEGF-like_dom

PCSK5 HSPG2 FRAS1 EYS STAB2 MEGF6 MUC17 LAMA3 LAMC2 LTBP1 LRP1B VWDE ADAM28 NOTCH2 EGFL6 STAB1

3.77e-162496716IPR000742
DomainEGF_1

HSPG2 EYS STAB2 MEGF6 MUC17 LAMA3 LAMC2 LTBP1 USH2A LRP1B VWDE ADAM28 NOTCH2 EGFL6 STAB1

1.30e-142556715PS00022
DomainEGF-like_CS

HSPG2 EYS STAB2 MEGF6 MUC17 LAMA3 LAMC2 LTBP1 LRP1B VWDE ADAM28 NOTCH2 EGFL6 STAB1

3.87e-132616714IPR013032
DomainEGF_2

HSPG2 EYS STAB2 MEGF6 MUC17 LAMA3 LAMC2 LTBP1 LRP1B VWDE ADAM28 NOTCH2 EGFL6 STAB1

4.76e-132656714PS01186
DomainEGF_Lam

HSPG2 STAB2 MEGF6 LAMA3 LAMC2 USH2A STAB1

3.44e-1135677SM00180
DomainEGF_3

HSPG2 EYS STAB2 MEGF6 MUC17 LTBP1 LRP1B VWDE ADAM28 NOTCH2 EGFL6 STAB1

3.87e-112356712PS50026
DomainLaminin_EGF

HSPG2 STAB2 MEGF6 LAMA3 LAMC2 USH2A STAB1

6.40e-1138677IPR002049
DomainEGF_CA

HSPG2 EYS STAB2 MEGF6 LTBP1 LRP1B NOTCH2 EGFL6 STAB1

4.99e-10122679SM00179
DomainEGF-like_Ca-bd_dom

HSPG2 EYS STAB2 MEGF6 LTBP1 LRP1B NOTCH2 EGFL6 STAB1

5.78e-10124679IPR001881
DomainEGF_LAM_2

HSPG2 STAB2 LAMA3 LAMC2 USH2A STAB1

9.40e-1030676PS50027
DomainEGF_LAM_1

HSPG2 STAB2 LAMA3 LAMC2 USH2A STAB1

9.40e-1030676PS01248
DomainLaminin_EGF

HSPG2 MEGF6 LAMA3 LAMC2 USH2A STAB1

2.54e-0935676PF00053
DomainEGF

HSPG2 EYS STAB2 MEGF6 LTBP1 LRP1B NOTCH2 STAB1

1.60e-08126678PF00008
DomainEGF_Ca-bd_CS

EYS MEGF6 LTBP1 LRP1B NOTCH2 EGFL6

1.30e-0697676IPR018097
DomainEGF_CA

EYS MEGF6 LTBP1 LRP1B NOTCH2 EGFL6

1.46e-0699676PS01187
DomainASX_HYDROXYL

EYS MEGF6 LTBP1 LRP1B NOTCH2 EGFL6

1.55e-06100676PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

EYS MEGF6 LTBP1 LRP1B NOTCH2 EGFL6

2.18e-06106676IPR000152
DomainLAMININ_IVA

HSPG2 LAMA3 LAMC2

2.44e-068673PS51115
DomainLaminin_B

HSPG2 LAMA3 LAMC2

2.44e-068673PF00052
DomainLamB

HSPG2 LAMA3 LAMC2

2.44e-068673SM00281
DomainLaminin_IV

HSPG2 LAMA3 LAMC2

2.44e-068673IPR000034
Domain-

STAB2 EGFL6 STAB1

7.13e-06116732.40.155.10
DomainGFP-like

STAB2 EGFL6 STAB1

7.13e-0611673IPR023413
DomainLAM_G_DOMAIN

HSPG2 EYS LAMA3 USH2A

1.02e-0538674PS50025
DomainLaminin_G_2

HSPG2 EYS LAMA3 USH2A

1.25e-0540674PF02210
DomainEGF_CA

MEGF6 LTBP1 LRP1B NOTCH2 EGFL6

1.42e-0586675PF07645
DomainLamG

HSPG2 EYS LAMA3 USH2A

1.84e-0544674SM00282
DomainFurin_repeat

PCSK5 FRAS1 ERBB4

3.46e-0518673IPR006212
DomainFU

PCSK5 FRAS1 ERBB4

3.46e-0518673SM00261
DomainLaminin_G

HSPG2 EYS LAMA3 USH2A

5.55e-0558674IPR001791
DomainEGF_extracell

STAB2 MEGF6 LRP1B STAB1

6.34e-0560674IPR013111
DomainEGF_2

STAB2 MEGF6 LRP1B STAB1

6.34e-0560674PF07974
DomainFAS1

STAB2 STAB1

7.57e-054672SM00554
DomainFAS1_domain

STAB2 STAB1

7.57e-054672IPR000782
Domain-

STAB2 STAB1

7.57e-0546722.30.180.10
DomainFAS1

STAB2 STAB1

7.57e-054672PS50213
DomainFasciclin

STAB2 STAB1

7.57e-054672PF02469
DomainhEGF

EYS MEGF6 NOTCH2

1.36e-0428673PF12661
DomainGF_recep_IV

PCSK5 ERBB4

1.88e-046672PF14843
DomainGF_recep_IV

PCSK5 ERBB4

1.88e-046672IPR032778
DomainWxxW_domain

CILP MUC2

1.88e-046672IPR025155
DomainMucin2_WxxW

CILP MUC2

1.88e-046672PF13330
Domain-

HSPG2 EYS LAMA3 USH2A

3.77e-04956742.60.120.200
DomainLaminin_G_1

HSPG2 EYS

6.83e-0411672PF00054
DomainEGF_3

STAB2 STAB1

8.18e-0412672PF12947
DomainEGF_dom

STAB2 STAB1

8.18e-0412672IPR024731
DomainLINK

STAB2 STAB1

9.64e-0413672SM00445
DomainLink_dom

STAB2 STAB1

9.64e-0413672IPR000538
DomainXlink

STAB2 STAB1

9.64e-0413672PF00193
DomainLINK_1

STAB2 STAB1

9.64e-0413672PS01241
DomainLINK_2

STAB2 STAB1

9.64e-0413672PS50963
DomainSEA

HSPG2 MUC17

1.12e-0314672SM00200
DomainConA-like_dom

HSPG2 EYS LAMA3 USH2A EGFL6

1.13e-03219675IPR013320
DomainVWD

MUC2 VWDE

1.47e-0316672SM00216
DomainVWF_type-D

MUC2 VWDE

1.47e-0316672IPR001846
DomainLaminin_N

LAMA3 USH2A

1.47e-0316672IPR008211
DomainLAMININ_NTER

LAMA3 USH2A

1.47e-0316672PS51117
DomainVWFD

MUC2 VWDE

1.47e-0316672PS51233
DomainLaminin_N

LAMA3 USH2A

1.47e-0316672PF00055
DomainVWD

MUC2 VWDE

1.47e-0316672PF00094
DomainLamNT

LAMA3 USH2A

1.47e-0316672SM00136
DomainTY

IGFBP5 SPOCK2

1.67e-0317672SM00211
Domain-

IGFBP5 SPOCK2

1.67e-03176724.10.800.10
DomainTHYROGLOBULIN_1_2

IGFBP5 SPOCK2

1.67e-0317672PS51162
DomainThyroglobulin_1

IGFBP5 SPOCK2

1.67e-0317672IPR000716
DomainThyroglobulin_1

IGFBP5 SPOCK2

1.67e-0317672PF00086
DomainTHYROGLOBULIN_1_1

IGFBP5 SPOCK2

1.67e-0317672PS00484
DomainWnt

WNT7A WNT11

2.08e-0319672IPR005817
DomainVWC_out

FRAS1 MUC2

2.08e-0319672SM00215
DomainWnt_CS

WNT7A WNT11

2.08e-0319672IPR018161
Domainwnt

WNT7A WNT11

2.08e-0319672PF00110
DomainWNT1

WNT7A WNT11

2.08e-0319672SM00097
DomainWNT1

WNT7A WNT11

2.08e-0319672PS00246
DomainSEA

HSPG2 MUC17

2.80e-0322672PF01390
DomainTNFR_c6

TNFRSF19 TNFRSF1B

2.80e-0322672PF00020
DomainSEA

HSPG2 MUC17

3.06e-0323672PS50024
DomainSEA_dom

HSPG2 MUC17

3.06e-0323672IPR000082
Pubmed

Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.

HSPG2 FRAS1 LAMA3 LAMC2 EGFL6

2.82e-092968522613833
Pubmed

Transcriptome-based systematic identification of extracellular matrix proteins.

HSPG2 FRAS1 LAMA3 LAMC2 SPOCK2 EGFL6

1.11e-087968618757743
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

HSPG2 FRAS1 LAMA3 LAMC2 LTBP1 MUC2

9.58e-0716768622159717
Pubmed

The γ3 chain of laminin is widely but differentially expressed in murine basement membranes: expression and functional studies.

HSPG2 LAMC2 RHO

2.02e-061368322222602
Pubmed

Basement membrane composition in the early mouse embryo day 7.

HSPG2 LAMA3 LAMC2

3.20e-061568315895400
Pubmed

Differential expression of laminin-5/ladsin subunits in human tissues and cancer cell lines and their induction by tumor promoter and growth factors.

LAMA3 LAMC2

3.77e-0626829010770
Pubmed

FEEL-1 and FEEL-2 are endocytic receptors for advanced glycation end products.

STAB2 STAB1

3.77e-06268212473645
Pubmed

Identifying Stabilin-1 and Stabilin-2 Double Knockouts in Reproduction and Placentation: A Descriptive Study.

STAB2 STAB1

3.77e-06268233008099
Pubmed

Exploring the transcriptomic network of multi-ligand scavenger receptor Stabilin-1- and Stabilin-2-deficient liver sinusoidal endothelial cells.

STAB2 STAB1

3.77e-06268233130055
Pubmed

Mechanism for phosphatidylserine-dependent erythrophagocytosis in mouse liver.

STAB2 STAB1

3.77e-06268221427291
Pubmed

Deficiency of liver sinusoidal scavenger receptors stabilin-1 and -2 in mice causes glomerulofibrotic nephropathy via impaired hepatic clearance of noxious blood factors.

STAB2 STAB1

3.77e-06268221293057
Pubmed

The complete sequence of perlecan, a basement membrane heparan sulfate proteoglycan, reveals extensive similarity with laminin A chain, low density lipoprotein-receptor, and the neural cell adhesion molecule.

HSPG2 RHOBTB3

3.77e-0626821744087
Pubmed

Stabilin-1 and stabilin-2 are both directed into the early endocytic pathway in hepatic sinusoidal endothelium via interactions with clathrin/AP-2, independent of ligand binding.

STAB2 STAB1

3.77e-06268215572036
Pubmed

Phenotypical and biochemical characterization of murine psoriasiform and fibrotic skin disease models in Stabilin-deficient mice.

STAB2 STAB1

3.77e-06268238946049
Pubmed

Stabilin-1 and -2 constitute a novel family of fasciclin-like hyaluronan receptor homologues.

STAB2 STAB1

3.77e-06268211829752
Pubmed

Microvesicle release from inner segments of healthy photoreceptors is a conserved phenomenon in mammalian species.

AGTPBP1 RHO

3.77e-06268236420970
Pubmed

Laminin 5 mutations in junctional epidermolysis bullosa: molecular basis of Herlitz vs. non-Herlitz phenotypes.

LAMA3 LAMC2

3.77e-06268211810295
Pubmed

Study of mucin turnover in the small intestine by in vivo labeling.

MUC17 MUC2

3.77e-06268229636525
Pubmed

FEEL-1, a novel scavenger receptor with in vitro bacteria-binding and angiogenesis-modulating activities.

STAB2 STAB1

3.77e-06268212077138
Pubmed

Association of Differentially Altered Liver Fibrosis with Deposition of TGFBi in Stabilin-Deficient Mice.

STAB2 STAB1

3.77e-06268237446152
Pubmed

Scavenging Endothelium of Pancreatic Islets: Differential Expression of Stabilin-1 and Stabilin-2 in Mice and Humans.

STAB2 STAB1

3.77e-06268227977633
Pubmed

Tumor necrosis factor-receptor 2 and TROY gene expression patterns in cutaneous squamous cell carcinoma in a Tunisian population.

TNFRSF19 TNFRSF1B

3.77e-06268222057614
Pubmed

Syndromic and non-syndromic forms of retinitis pigmentosa: a comprehensive Italian clinical and molecular study reveals new mutations.

EYS RHO

3.77e-06268225366773
Pubmed

Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects.

HSPG2 FRAS1 LAMA3

3.93e-061668316880404
Pubmed

Mesenchymal-epithelial interaction regulates gastrointestinal tract development in mouse embryos.

IGFBP5 LHX8 MUC2

5.71e-061868335830795
Pubmed

Cell-Intrinsic Control of Interneuron Migration Drives Cortical Morphogenesis.

ERBB4 LHX8 AGTPBP1

6.77e-061968329474907
Pubmed

Ldb1 is essential for development of Nkx2.1 lineage derived GABAergic and cholinergic neurons in the telencephalon.

ERBB4 LDB1 LHX8

9.27e-062168324157949
Pubmed

PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα.

HSPG2 LAMA3 LAMC2

9.27e-062168327856617
Pubmed

High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.

IGFBP5 WNT7A WNT11 LTBP1 TNFRSF1B NOTCH2 PDLIM4

1.01e-0538368719453261
Pubmed

Highly oxidized albumin is cleared by liver sinusoidal endothelial cells via the receptors stabilin-1 and -2.

STAB2 STAB1

1.13e-05368237926735
Pubmed

Assignment of mouse nicein genes to chromosomes 1 and 18.

LAMA3 LAMC2

1.13e-0536828012114
Pubmed

Marginal zone B cells mediate a CD4 T-cell-dependent extrafollicular antibody response following RBC transfusion in mice.

S1PR1 NOTCH2

1.13e-05368233876205
Pubmed

Polymerized laminin-332 matrix supports rapid and tight adhesion of keratinocytes, suppressing cell migration.

LAMA3 LAMC2

1.13e-05368222563463
Pubmed

Laminin-332 (Laminin-5) is the major motility ligand for B cell chronic lymphocytic leukemia.

LAMA3 LAMC2

1.13e-05368217482449
Pubmed

Laminin-5 mutational analysis in an Italian cohort of patients with junctional epidermolysis bullosa.

LAMA3 LAMC2

1.13e-05368215373767
Pubmed

Passive transfer of anti-laminin 5 antibodies induces subepidermal blisters in neonatal mice.

LAMA3 LAMC2

1.13e-0536828833897
Pubmed

Expression and chain assembly of human laminin-332 in an insect cell-free translation system.

LAMA3 LAMC2

1.13e-05368218603785
Pubmed

Laminin-5 suppresses chondrogenic differentiation of murine teratocarcinoma cell line ATDC5.

LAMA3 LAMC2

1.13e-05368216165127
Pubmed

Laminin‑332 mediates proliferation, apoptosis, invasion, migration and epithelial‑to‑mesenchymal transition in pancreatic ductal adenocarcinoma.

LAMA3 LAMC2

1.13e-05368233179081
Pubmed

Stabilin receptors clear LPS and control systemic inflammation.

STAB2 STAB1

1.13e-05368234816100
Pubmed

Fibroblasts contribute to the deposition of laminin 5 in the extracellular matrix.

LAMA3 LAMC2

1.13e-05368215149852
Pubmed

Two atypical enteropathogenic Escherichia coli strains induce the production of secreted and membrane-bound mucins to benefit their own growth at the apical surface of human mucin-secreting intestinal HT29-MTX cells.

MUC17 MUC2

1.13e-05368220065027
Pubmed

CD19 regulates ADAM28-mediated Notch2 cleavage to control the differentiation of marginal zone precursors to MZ B cells.

ADAM28 NOTCH2

1.13e-05368228707394
Pubmed

Herlitz junctional epidermolysis bullosa keratinocytes display heterogeneous defects of nicein/kalinin gene expression.

LAMA3 LAMC2

1.13e-0536828113417
Pubmed

Genotype, Clinical Course, and Therapeutic Decision Making in 76 Infants with Severe Generalized Junctional Epidermolysis Bullosa.

LAMA3 LAMC2

1.13e-05368227375110
Pubmed

Synthetic D-amino acid peptide inhibits tumor cell motility on laminin-5.

LAMA3 LAMC2

1.13e-05368216537560
Pubmed

Quantitative analysis of laminin 5 gene expression in human keratinocytes.

LAMA3 LAMC2

1.13e-05368215854126
Pubmed

Uncoordinated production of Laminin-5 chains in airways epithelium of allergic asthmatics.

LAMA3 LAMC2

1.13e-05368216179086
Pubmed

Characteristics of rodent intestinal mucin Muc3 and alterations in a mouse model of human cystic fibrosis.

MUC17 MUC2

1.13e-05368211352827
Pubmed

Laminin-5 activates extracellular matrix production and osteogenic gene focusing in human mesenchymal stem cells.

LAMA3 LAMC2

1.13e-05368217137774
Pubmed

Differential expression of laminin-5 subunits during incisor and molar development in the mouse.

LAMA3 LAMC2

1.13e-05368210853832
Pubmed

Localization of laminin-5, HD1/plectin, and BP230 in the submandibular glands of developing and adult mice.

LAMA3 LAMC2

2.25e-05468210651091
Pubmed

Bone morphogenetic protein 1 is an extracellular processing enzyme of the laminin 5 gamma 2 chain.

LAMA3 LAMC2

2.25e-05468210806203
Pubmed

Invasive breast cancer induces laminin-332 upregulation and integrin β4 neoexpression in myofibroblasts to confer an anoikis-resistant phenotype during tissue remodeling.

LAMA3 LAMC2

2.25e-05468222673183
Pubmed

Utility of molecular testing for related retinal dystrophies.

USH2A RHO

2.25e-05468216767206
Pubmed

Structural requirement of carboxyl-terminal globular domains of laminin alpha 3 chain for promotion of rapid cell adhesion and migration by laminin-5.

LAMA3 LAMC2

2.25e-05468210801807
Pubmed

Developmental expression of nicein adhesion protein (laminin-5) subunits suggests multiple morphogenic roles.

LAMA3 LAMC2

2.25e-0546828081888
Pubmed

16p11.2 transcription factor MAZ is a dosage-sensitive regulator of genitourinary development.

MAZ WNT11

2.25e-05468229432158
Pubmed

Novel DNA polymorphism in the mouse tumor necrosis factor receptors type 1 and type 2.

TNFRSF1B RHO

2.25e-0546828380565
Pubmed

Interaction of insulin-like growth factor binding protein-3 with latent transforming growth factor-beta binding protein-1.

IGFBP5 LTBP1

2.25e-05468212962157
Pubmed

Conjugation of LG domains of agrins and perlecan to polymerizing laminin-2 promotes acetylcholine receptor clustering.

HSPG2 LAMC2

2.25e-05468216219760
Pubmed

Type XVII collagen (BP180) can function as a cell-matrix adhesion molecule via binding to laminin 332.

LAMA3 LAMC2

2.25e-05468221034821
Pubmed

Butyrate enemas upregulate Muc genes expression but decrease adherent mucus thickness in mice colon.

MUC17 MUC2

2.25e-05468218198997
Pubmed

Targeting of Scavenger Receptors Stabilin-1 and Stabilin-2 Ameliorates Atherosclerosis by a Plasma Proteome Switch Mediating Monocyte/Macrophage Suppression.

STAB2 STAB1

2.25e-05468236325910
Pubmed

Bisecting GlcNAc residues on laminin-332 down-regulate galectin-3-dependent keratinocyte motility.

LAMA3 LAMC2

2.25e-05468219940114
Pubmed

Deficiency for scavenger receptors Stabilin-1 and Stabilin-2 leads to age-dependent renal and hepatic depositions of fasciclin domain proteins TGFBI and Periostin in mice.

STAB2 STAB1

2.25e-05468237357460
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

HSPG2 MEGF6 LAMA3 SPOCK2 LTBP1

2.46e-0517568528071719
Pubmed

Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence.

WNT7A ADAM28 NOTCH2

2.79e-053068319054571
Pubmed

Recombinant human laminin-5 domains. Effects of heterotrimerization, proteolytic processing, and N-glycosylation on alpha3beta1 integrin binding.

LAMA3 LAMC2

3.75e-05568214612440
Pubmed

Marginal zone B cells regulate antigen capture by marginal zone macrophages.

S1PR1 NOTCH2

3.75e-05568221257969
Pubmed

IAP insertion in the murine LamB3 gene results in junctional epidermolysis bullosa.

LAMA3 LAMC2

3.75e-0556829271670
Pubmed

Multifaceted transcriptional regulation of the murine intestinal mucus layer by endogenous microbiota.

MUC17 MUC2

3.75e-05568218035521
Pubmed

Comparison of the four mouse fasciclin-containing genes expression patterns during valvuloseptal morphogenesis.

STAB2 STAB1

3.75e-05568215907457
Pubmed

Laminin 5 regulates polycystic kidney cell proliferation and cyst formation.

LAMA3 LAMC2

3.75e-05568216870608
Pubmed

Expression of type XXIII collagen mRNA and protein.

LAMA3 LAMC2

3.75e-05568216728390
Pubmed

Hundreds of variants clustered in genomic loci and biological pathways affect human height.

PCSK5 CTU2 LTBP1 ADAM28 PML

4.43e-0519868520881960
Pubmed

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

EYS STAB2 LINGO2 USH2A LRP1B

4.54e-0519968523382691
Pubmed

A genomic atlas of mouse hypothalamic development.

IGFBP5 NEXMIF WNT7A LTBP1 LHX8

5.22e-0520568520436479
Pubmed

Expression and localization of laminin-5 subunits in the mouse incisor.

LAMA3 LAMC2

5.62e-0566829506922
Pubmed

Junctional Epidermolysis Bullosa

LAMA3 LAMC2

5.62e-05668220301304
Pubmed

Complementary expression of IGF-II and IGFBP-5 during anterior pituitary development.

IGFBP5 CGA

5.62e-05668211944940
Pubmed

Retinal remodeling triggered by photoreceptor degenerations.

AGTPBP1 RHO

5.62e-05668212866125
Pubmed

Identification of in vivo roles of ErbB4-JMa and its direct nuclear signaling using a novel isoform-specific knock out mouse.

ERBB4 PRSS12

7.86e-05768236241655
Pubmed

A new nomenclature for the laminins.

LAMA3 LAMC2

7.86e-0576827921537
Pubmed

Whirlin replacement restores the formation of the USH2 protein complex in whirlin knockout photoreceptors.

USH2A RHO

7.86e-05768221212183
Pubmed

MYC in pancreatic cancer: novel mechanistic insights and their translation into therapeutic strategies.

ZBTB17 NOTCH2

7.86e-05768226119937
Pubmed

Variation in WNT genes is associated with non-syndromic cleft lip with or without cleft palate.

WNT7A WNT11

7.86e-05768218413325
Pubmed

PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.

SEMA6B LRRC3B LINGO2 LRIT1

8.39e-0511768417145500
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

PCSK5 HSPG2 MEGF6 LTBP1

8.67e-0511868421078624
Pubmed

Isl1 directly controls a cholinergic neuronal identity in the developing forebrain and spinal cord by forming cell type-specific complexes.

LDB1 LHX8

1.05e-04868224763339
Pubmed

Expression and localization of laminin-5 subunits during mouse tooth development.

LAMA3 LAMC2

1.05e-0486829489770
Pubmed

Cloning and expression analyses of mouse dystroglycan gene: specific expression in maternal decidua at the peri-implantation stage.

LAMA3 LAMC2

1.05e-0486828872465
Pubmed

Spatial and temporal control of laminin-332 and -511 expressions during hair morphogenesis.

LAMA3 LAMC2

1.05e-04868223529140
Pubmed

Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination.

WNT7A WNT11 CGA

1.09e-044768316678101
Pubmed

Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis.

WNT7A WNT11 TNFRSF19

1.09e-044768328813421
Pubmed

WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth.

WNT7A WNT11 CGA

1.31e-045068318351662
Pubmed

Elongation factor 1 alpha1 and genes associated with Usher syndromes are downstream targets of GBX2.

USH2A NOTCH2

1.34e-04968223144817
Pubmed

Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly.

LAMA3 LAMC2

1.34e-04968212482924
Pubmed

Two NOD Idd-associated intervals contribute synergistically to the development of autoimmune exocrinopathy (Sjögren's syndrome) on a healthy murine background.

IGFBP5 LAMC2

1.34e-04968212115247
Pubmed

Wnt signaling mediates reorientation of outer hair cell stereociliary bundles in the mammalian cochlea.

WNT7A WNT11

1.34e-04968212702652
InteractionNTN5 interactions

FRAS1 LTBP1 LRP1B VWDE NOTCH2

1.41e-0824675int:NTN5
InteractionIGFL3 interactions

PCSK5 FRAS1 LAMA3 LRP1B VWDE NOTCH2

1.81e-0775676int:IGFL3
InteractionPRG2 interactions

SEMA6B PCSK5 HSPG2 FRAS1 PRSS12 LAMC2 VWDE NOTCH2

4.59e-06285678int:PRG2
InteractionFBXO2 interactions

SEMA6B PCSK5 HSPG2 FRAS1 WNT7A LAMA3 LAMC2 LRP1B NOTCH2

8.40e-06411679int:FBXO2
InteractionZNF408 interactions

HSPG2 FRAS1 LTBP1 LRP1B NOTCH2 PDLIM4

8.70e-06145676int:ZNF408
InteractionRNASE4 interactions

LRP1B VWDE NOTCH2

1.25e-0514673int:RNASE4
InteractionPROK2 interactions

PROK2 LRP1B VWDE

1.25e-0514673int:PROK2
InteractionZNF444 interactions

HSPG2 FRAS1 CTU2 TNFRSF19 NOTCH2

2.73e-05106675int:ZNF444
InteractionZFP41 interactions

FRAS1 LTBP1 LRP1B NOTCH2

3.86e-0557674int:ZFP41
InteractionLYPD1 interactions

PCSK5 FRAS1 VWDE NOTCH2

4.14e-0558674int:LYPD1
InteractionCEACAM8 interactions

PCSK5 FRAS1 LAMA3 LTBP1 VWDE

4.76e-05119675int:CEACAM8
InteractionFBLN2 interactions

HSPG2 LAMC2 LTBP1 VWDE

6.89e-0566674int:FBLN2
Cytoband15q22

CILP PML

8.55e-042968215q22
GeneFamilyLaminin subunits

LAMA3 LAMC2

4.67e-0412492626
GeneFamilyWnt family|Endogenous ligands

WNT7A WNT11

1.19e-0319492360
GeneFamilyCD molecules|Mucins

MUC17 MUC2

1.46e-0321492648
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

STAB2 STAB1

2.42e-03274921253
GeneFamilyCD molecules|Tumor necrosis factor receptor superfamily|Death inducing signaling complex

TNFRSF19 TNFRSF1B

2.79e-0329492782
GeneFamilyRing finger proteins

RNF14 MARCHF2 RFFL PML

6.49e-0327549458
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

HSPG2 LINGO2 LRIT1

9.46e-03161493593
CoexpressionNABA_MATRISOME

SEMA6B PCSK5 HSPG2 FRAS1 EYS IGFBP5 MEGF6 CILP MUC17 PRSS12 WNT7A WNT11 LAMA3 LAMC2 SPOCK2 LTBP1 MUC2 USH2A VWDE ADAM28 EGFL6

7.46e-1410266821M5889
CoexpressionNABA_MATRISOME

SEMA6B PCSK5 HSPG2 FRAS1 IGFBP5 MEGF6 CILP MUC17 PRSS12 WNT7A WNT11 LAMA3 LAMC2 SPOCK2 LTBP1 MUC2 VWDE ADAM28 EGFL6

6.20e-1210086819MM17056
CoexpressionNABA_CORE_MATRISOME

HSPG2 FRAS1 EYS IGFBP5 CILP LAMA3 LAMC2 SPOCK2 LTBP1 USH2A VWDE

1.25e-102756811M5884
CoexpressionNABA_ECM_GLYCOPROTEINS

FRAS1 EYS IGFBP5 CILP LAMA3 LAMC2 LTBP1 USH2A VWDE

2.05e-09196689M3008
CoexpressionNABA_CORE_MATRISOME

HSPG2 FRAS1 IGFBP5 CILP LAMA3 LAMC2 SPOCK2 LTBP1 VWDE

3.31e-08270689MM17057
CoexpressionNABA_ECM_GLYCOPROTEINS

FRAS1 IGFBP5 CILP LAMA3 LAMC2 LTBP1 VWDE

6.51e-07191687MM17059
CoexpressionBENPORATH_SUZ12_TARGETS

PROK2 ERBB4 IGFBP5 LRRC3B NEXMIF WNT7A WNT11 LAMA3 SPOCK2 LHX8 TNFRSF1B NOTCH2 EGFL6

2.20e-0610356813M9898
CoexpressionNABA_BASEMENT_MEMBRANES

HSPG2 LAMA3 LAMC2 USH2A

3.53e-0640684M5887
CoexpressionNABA_MATRISOME_BLEO_FIBROTIC_LUNG

HSPG2 LAMA3 LAMC2

1.84e-0520683MM17053
CoexpressionNABA_MATRISOME_ASSOCIATED

SEMA6B PCSK5 MEGF6 MUC17 PRSS12 WNT7A WNT11 MUC2 ADAM28 EGFL6

1.96e-057386810MM17058
CoexpressionNABA_MATRISOME_ASSOCIATED

SEMA6B PCSK5 MEGF6 MUC17 PRSS12 WNT7A WNT11 MUC2 ADAM28 EGFL6

2.28e-057516810M5885
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

GPR155 MEGF6 LRRC3B PRSS12 WNT7A FRS3 LAMA3 LAMC2 SPOCK2 MUC2 LRP1B AGTPBP1

2.46e-0511066812M39071
CoexpressionVART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN

PROK2 WNT7A FRS3 NOTCH2 STAB1

2.70e-05135685M5825
CoexpressionHEBERT_MATRISOME_TNBC_LUNG_METASTASIS

HSPG2 LAMA3 LAMC2

2.85e-0523683M48001
CoexpressionMARTENS_TRETINOIN_RESPONSE_UP

SEMA6B CILP WNT11 CAMK1G TNFRSF1B MUC2 RTP4 GPRIN2 RHO PDLIM4

6.79e-058556810M2098
CoexpressionTRAVAGLINI_LUNG_ALVEOLAR_EPITHELIAL_TYPE_1_CELL

HSPG2 WNT7A LAMA3 LAMC2 SPOCK2 AGTPBP1 GPRIN2

6.91e-05391687M41659
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_LATE_MESOTHELIAL_CELL

HSPG2 DPYD FRAS1 MEGF6 WFDC2 LAMA3 LAMC2 SPOCK2 PDLIM4

8.28e-05704689M45672
CoexpressionDESCARTES_ORGANOGENESIS_EPITHELIAL_CELLS

FRAS1 WFDC2 LAMC2 VWDE ADAM28

9.29e-05175685MM3643
CoexpressionGSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_PDC_UP

STAB2 IGFBP5 CILP BRINP1 PDLIM4

1.58e-04196685M4999
CoexpressionGSE24574_BCL6_HIGH_TFH_VS_TFH_CD4_TCELL_UP

PCSK5 ERBB4 BRINP1 S1PR1 STAB1

1.62e-04197685M8337
CoexpressionDESCARTES_FETAL_LIVER_MESOTHELIAL_CELLS

ERBB4 IGFBP5 LAMA3 LAMC2 SPOCK2 PDLIM4

1.62e-04313686M40228
CoexpressionGSE28449_WT_VS_LRF_KO_GERMINAL_CENTER_BCELL_UP

PCSK5 RHOBTB3 CGA LAMA3 TNFRSF1B

1.70e-04199685M8347
CoexpressionGSE19888_CTRL_VS_A3R_ACTIVATION_MAST_CELL_DN

ERBB4 WNT11 SPOCK2 S1PR1 NOTCH2

1.70e-04199685M7326
CoexpressionGSE369_SOCS3_KO_VS_WT_LIVER_DN

TNFRSF19 CAMK1G PRR11 S1PR1 DCAF5

1.74e-04200685M5963
CoexpressionGSE7852_TREG_VS_TCONV_FAT_DN

SMYD4 ATP11B PHF6 RTP4 S1PR1

1.74e-04200685M5735
CoexpressionHE_LIM_SUN_FETAL_LUNG_C3_GRIA2_POS_ARTERIAL_ENDO_CELL

PCSK5 TNFRSF19 LTBP1 TNFRSF1B

2.31e-04115684M45752
CoexpressionCERVERA_SDHB_TARGETS_1_UP

PCSK5 MEGF6 LAMC2 TNFRSF19

2.71e-04120684M15549
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_200

FRAS1 ERBB4 WFDC2 LAMC2 LTBP1 EGFL6

1.89e-05175676gudmap_kidney_P4_CapMesRenVes_Crym_200
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#2

FRAS1 LRRC3B PRSS12 MARCHF2 SPOCK2 LTBP1 LINGO2

2.91e-05281677Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_2500_K2
CoexpressionAtlasFacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#2

PRSS12 MARCHF2 SPOCK2 LTBP1 LINGO2

4.03e-05121675Facebase_RNAseq_e9.5_Maxillary Arch_1000_K2
CoexpressionAtlasFacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_1000_k-means-cluster#1

PRSS12 MARCHF2 SPOCK2 LTBP1 LINGO2

4.70e-05125675Facebase_RNAseq_e9.5_Facial Mesenchyne_1000_K1
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#1

WFDC2 PRSS12 MARCHF2 SPOCK2 LINGO2

4.70e-05125675Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000_K1
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000_k-means-cluster#5

FRAS1 PRSS12 MARCHF2 SPOCK2 LINGO2

5.27e-05128675Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_1000_K5
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000_k-means-cluster#3

PRSS12 MARCHF2 SPOCK2 LTBP1 LINGO2

5.47e-05129675Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_1000_K3
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#4

FRAS1 WFDC2 PRSS12 MARCHF2 SPOCK2 LTBP1 LINGO2

6.12e-05316677Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_2500_K4
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#1_top-relative-expression-ranked_500

NEXMIF TNFRSF19 S1PR1 EGFL6

9.30e-0575674gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k1_500
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_200

WFDC2 SPOCK2 LTBP1 NOTCH2 EGFL6

1.80e-04166675gudmap_kidney_P3_CapMes_Crym_200
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

FRAS1 PRSS12 MARCHF2 SPOCK2 LTBP1 LINGO2

1.88e-04265676Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_2500_K5
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_top-relative-expression-ranked_1000

DPYD FRAS1 IGFBP5 WFDC2 WNT7A LAMA3 LAMC2 SPOCK2 LHX8 ADAM28

1.93e-048006710gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_1000
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_1000

GPR155 FRAS1 LRRC3B PRSS12 NEXMIF MARCHF2 SPOCK2 LTBP1 LINGO2 LHX8 EGFL6

2.04e-049676711Facebase_RNAseq_e8.5_Paraxial Mesoderm_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#3

FRAS1 PRSS12 MARCHF2 SPOCK2 LTBP1 LINGO2

2.39e-04277676Facebase_RNAseq_e10.5_Medial Nasal Eminence_2500_K3
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_500

FRAS1 ERBB4 WFDC2 LAMC2 LTBP1 NOTCH2 EGFL6

2.55e-04398677gudmap_kidney_P4_CapMesRenVes_Crym_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500_k-means-cluster#2

MARCHF2 SPOCK2 LINGO2

2.73e-0440673Facebase_RNAseq_e10.5_Mandibular Arch_500_K2
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_2500_k-means-cluster#5

FRAS1 WFDC2 PRSS12 MARCHF2 SPOCK2 LTBP1 LINGO2

2.87e-04406677Facebase_RNAseq_e10.5_Olfactory Pit_2500_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#4

FRAS1 PRSS12 MARCHF2 SPOCK2 LTBP1 LINGO2

3.06e-04290676Facebase_RNAseq_e10.5_Mandibular Arch_2500_K4
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#1

PRSS12 MARCHF2 SPOCK2 LINGO2

3.17e-04103674Facebase_RNAseq_e10.5_Mandibular Arch_1000_K1
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#3

FRAS1 PRSS12 MARCHF2 SPOCK2 LTBP1 LINGO2

3.54e-04298676Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_2500_K3
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_k-means-cluster#4_top-relative-expression-ranked_1000

WFDC2 LAMA3 LAMC2 ADAM28

3.79e-04108674gudmap_developingLowerUrinaryTract_P1_bladder_B_1000_k4
CoexpressionAtlasFacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#3

FRAS1 PRSS12 MARCHF2 SPOCK2 LTBP1 LINGO2

4.00e-04305676Facebase_RNAseq_e9.5_Maxillary Arch_2500_K3
CoexpressionAtlasFacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_2500_k-means-cluster#4

FRAS1 PRSS12 MARCHF2 SPOCK2 LTBP1 LINGO2

4.14e-04307676Facebase_RNAseq_e9.5_Facial Mesenchyne_2500_K4
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#4

FRAS1 LRRC3B MARCHF2 SPOCK2 LTBP1 LINGO2

4.43e-04311676Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K4
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#3

FRAS1 PRSS12 MARCHF2 SPOCK2 LTBP1 LINGO2

4.43e-04311676Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_2500_K3
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#2

FRAS1 PRSS12 MARCHF2 SPOCK2 LTBP1 LINGO2

4.59e-04313676Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K2
CoexpressionAtlasStromal Cells, LEC.MLN, gp38+ CD31+, Lymph Node, avg-4

HSPG2 STAB2 IGFBP5 LAMC2 LTBP1 S1PR1 STAB1

4.60e-04439677GSM777059_500
CoexpressionAtlasMesoderm Day 5_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05

HSPG2 ERBB4 MEGF6 WFDC2 RHOBTB3 TNFRSF19

5.15e-04320676PCBC_ratio_MESO-5_vs_DE_cfr-2X-p05
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_1000

GPR155 IGFBP5 WFDC2 LAMC2 SPOCK2 LTBP1 PRR11 NOTCH2 EGFL6

5.52e-04749679gudmap_kidney_P3_CapMes_Crym_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_k-means-cluster#1_top-relative-expression-ranked_500

WFDC2 LAMC2 ADAM28

6.28e-0453673gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_500_k1
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#4

FRAS1 PRSS12 MARCHF2 SPOCK2 LTBP1 LINGO2

6.45e-04334676Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_2500_K4
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K3

LRRC3B NEXMIF S1PR1 STAB1

7.63e-04130674facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K3
ToppCellAT1_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

HSPG2 FRAS1 WNT7A LAMA3 LAMC2 SPOCK2 GPRIN2

9.86e-09176687458720776b0151cd55acc352d509599cb62f0ca8
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_GGH|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 IGFBP5 LRRC3B LAMA3 RTP4 VWDE EGFL6

1.03e-08177687d7976eac7e27044f6a859cc0c3398d08576e8c01
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HSPG2 RHOBTB3 WNT7A LAMA3 LAMC2 SPOCK2 GPRIN2

2.14e-08197687c9c968e223e7814cd8d22975d849a31b7e0af7aa
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HSPG2 RHOBTB3 WNT7A LAMA3 LAMC2 SPOCK2 GPRIN2

2.14e-08197687734b8db5bb4917c9ce92ed342fe6c22b64b0d3c5
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HSPG2 RHOBTB3 WNT7A LAMA3 LAMC2 SPOCK2 GPRIN2

2.14e-08197687e344455e62b3fe94bb242dc0db58d19a1d3878c7
ToppCellAT1-AT2_cells|World / lung cells shred on cell class, cell subclass, sample id

HSPG2 RHOBTB3 WNT7A LAMA3 LAMC2 SPOCK2 GPRIN2

2.22e-08198687a5b3617ea2ed4bffba59edcf6284799c2b3bbb29
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_alveolar-AT1|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

WFDC2 RHOBTB3 WNT7A LAMA3 LAMC2 SPOCK2 GPRIN2

2.38e-082006873d51aebf626dd4656ab4aac8a20d761b8062c42d
ToppCellBiopsy_Control_(H.)-Epithelial-AT1|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

HSPG2 RHOBTB3 WNT7A LAMA3 LAMC2 SPOCK2 GPRIN2

2.38e-082006873a9633f5913f12b6865fc777c84f3f3ba795a78d
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HSPG2 FRAS1 IGFBP5 LAMA3 LAMC2 SPOCK2

3.04e-071776869af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 IGFBP5 LRRC3B LAMA3 RTP4 NOTCH2

3.15e-071786862a36475c260088f69f3b8c282d910e5eaa5c5c2d
ToppCellAdult-Epithelial-club_cell-D122|Adult / Lineage, Cell type, age group and donor

FRAS1 ERBB4 PRSS12 RHOBTB3 LRP1B ADAM28

3.15e-0717868635a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HSPG2 FRAS1 WNT7A LAMA3 LAMC2 SPOCK2

3.59e-07182686573771130247e869e4e58f22d4a1cb31989635cf
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HSPG2 FRAS1 WNT7A LAMA3 LAMC2 SPOCK2

3.59e-071826866cfaa2b3b3974c13b01c943f4adb70768dcc35e4
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 LRRC3B PRSS12 LTBP1 NOTCH2 EGFL6

3.82e-07184686e2de27cee3ea80f9b7a9a7884ceceeaa67b3214a
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SEMA6B LAMA3 USH2A LRP1B AGTPBP1 STAB1

4.07e-0718668623b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FRAS1 IGFBP5 LRRC3B WNT11 LINGO2 LRP1B

4.07e-071866868915436d09775f2828a7678af203b1082b36e21c
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

HSPG2 FRAS1 WNT7A LAMA3 LAMC2 SPOCK2

4.20e-071876864ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCellAT1_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

HSPG2 FRAS1 LAMA3 LAMC2 SPOCK2 PDLIM4

4.20e-07187686f1dda349335e08dbfc8395d373924037f5ad2fd6
ToppCellControl-Epithelial-ATI|Control / Disease state, Lineage and Cell class

WFDC2 WNT7A LAMA3 LAMC2 SPOCK2 GPRIN2

4.20e-07187686fdd1c57b61ca9392ac27661a82729f37593df63c
ToppCelldroplet-Lung-21m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCSK5 DPYD IGFBP5 RHOBTB3 SPOCK2 TNFRSF19

4.47e-07189686cd42ce4aa217d0bd95e0cc0ba357bdfeb3e55a48
ToppCelldroplet-Lung-21m-Mesenchymal-myofibroblast-myofibroblast_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCSK5 DPYD IGFBP5 RHOBTB3 SPOCK2 TNFRSF19

4.47e-07189686102501eee7760d5882dec41ea9d00147b3f4fb73
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA6B PCSK5 HSPG2 LAMA3 TNFRSF1B AGTPBP1

4.47e-071896866463890d8dbee4bc198f91628a5f784970de786a
ToppCelldroplet-Lung-21m-Mesenchymal-myofibroblast|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCSK5 DPYD IGFBP5 RHOBTB3 SPOCK2 TNFRSF19

4.47e-071896866e83bf855d4771885b60bb8992df2f9b508eef97
ToppCelldroplet-Kidney-nan-3m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 IGFBP5 LRRC3B LTBP1 RTP4 S1PR1

4.76e-07191686dc58d45fafd224d2761aefbe0ce79f66b50c1c03
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HSPG2 FRAS1 WNT7A LAMA3 LAMC2 SPOCK2

4.76e-07191686ce76b156b153a2c7c9f2fb8e563b69c81073fbe5
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HSPG2 FRAS1 WNT7A LAMA3 LAMC2 SPOCK2

4.76e-07191686c006f5a6e3a32b79ac99a78304bdd5116fc0d5e0
ToppCellLPS-antiTNF-Endothelial-Endothelial-Artery|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCSK5 HSPG2 LRRC3B SPOCK2 TNFRSF19 LTBP1

4.76e-071916864b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HSPG2 FRAS1 WNT7A LAMA3 LAMC2 SPOCK2

4.91e-07192686790282d4232311df3dac4ad97c80fc53443beccc
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HSPG2 FRAS1 WNT7A LAMA3 LAMC2 SPOCK2

4.91e-07192686b2d9bffccd6264b4f12d88a0780646ee0b41969f
ToppCellE16.5-samps-Epithelial-Alveolar_epithelial_precursor|E16.5-samps / Age Group, Lineage, Cell class and subclass

IGFBP5 WFDC2 NEXMIF LAMA3 LAMC2 EGFL6

5.06e-07193686c1817ad675b9f9d2d3436c8b9646edf89f0d4c82
ToppCellE16.5-samps-Epithelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

IGFBP5 WFDC2 NEXMIF LAMA3 LAMC2 EGFL6

5.06e-071936861cb5a1cffa2b4a3bfecca16b791c1992edeb237d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA6B PCSK5 HSPG2 LAMA3 TNFRSF1B AGTPBP1

5.37e-071956866bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCellAT1_cells|World / lung cells shred on cell class, cell subclass, sample id

HSPG2 WNT7A LAMA3 LAMC2 SPOCK2 GPRIN2

5.37e-07195686792d6a49b0a875a00569071183d195287a9925c5
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA6B HSPG2 LAMA3 TNFRSF1B S1PR1 AGTPBP1

5.37e-07195686d35102f95bb1e419d2df05ff0a01b6c5c923acef
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RHOBTB3 WNT7A LAMA3 LAMC2 SPOCK2 GPRIN2

5.54e-071966866731fef8c148b6681d6ed38afdf23c8213e0bbbe
ToppCellEpithelial-A_(AT1)|World / shred on cell class and cell subclass (v4)

HSPG2 FRAS1 WNT7A LAMA3 LAMC2 SPOCK2

5.54e-07196686484bbc6b1f58bc260964babb949d14f5df101393
ToppCellEpithelial-Epithelial-A_(AT1)|Epithelial / shred on cell class and cell subclass (v4)

HSPG2 FRAS1 WNT7A LAMA3 LAMC2 SPOCK2

5.54e-0719668641b21a18125cc95bc8adde3369e4abd029cf137d
ToppCellEpithelial_cells-AT1_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

HSPG2 WNT7A LAMA3 LAMC2 SPOCK2 GPRIN2

5.54e-071966866c99d29162848161c1f166a032320f87a5d5a631
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RHOBTB3 WNT7A LAMA3 LAMC2 SPOCK2 GPRIN2

5.54e-071966866856317cd0cdcb88fe54b4ae905d91e13495b1c4
ToppCellAT1_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

HSPG2 WNT7A LAMA3 LAMC2 SPOCK2 GPRIN2

5.70e-0719768680d81be244c94c435accb643449b4ce6a3462c7f
ToppCellASK440-Epithelial-Type_1|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

RHOBTB3 WNT7A LAMA3 LAMC2 SPOCK2 AGTPBP1

5.70e-07197686782449c522c9e16e72bf999a73090688a3aefe06
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

HSPG2 RHOBTB3 WNT7A LAMA3 LAMC2 SPOCK2

5.70e-0719768669d5b8588046d119b5dff9a7fd6f49e97e00a5b7
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

HSPG2 RHOBTB3 WNT7A LAMA3 LAMC2 SPOCK2

5.70e-07197686e6cbfa267eb2e05b441fd034786faae07bb0e081
ToppCellControl_saline-Epithelial_alveolar-AT_1-Differentiating_AT1|Control_saline / Treatment groups by lineage, cell group, cell type

FRAS1 IGFBP5 WFDC2 LAMA3 LAMC2 SPOCK2

5.87e-0719868685f424cd9bb3117c9e322031024aabb87696ce47
ToppCellControl_saline-Epithelial_alveolar-AT_1|Control_saline / Treatment groups by lineage, cell group, cell type

FRAS1 IGFBP5 WFDC2 LAMA3 LAMC2 SPOCK2

5.87e-071986869b161285df7a4e51618f3517cfc5b8221ba55786
ToppCellEpithelial_cells-AT1-AT2_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

HSPG2 RHOBTB3 WNT7A LAMA3 LAMC2 SPOCK2

5.87e-07198686fbc46b20bcd44f2083170aacbc6f5dd00fba685c
ToppCellmedial-2-Epithelial-Alveolar_Epithelial_Type_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HSPG2 WNT7A LAMA3 LAMC2 SPOCK2 GPRIN2

6.05e-07199686456460c761e26ed4b1d88d9bee4d2a7c9bd9d416
ToppCellBrain_organoid-organoid_Velasco_nature-6_mon-Radial_glial-oRG/Astroglia|6_mon / Sample Type, Dataset, Time_group, and Cell type.

IGFBP5 LRRC3B LTBP1 S1PR1 NOTCH2 PDLIM4

6.05e-071996860b96fad1be02f0fe7a608207770cc56a6b6b291e
ToppCellmedial-Epithelial-Alveolar_Epithelial_Type_1-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HSPG2 WNT7A LAMA3 LAMC2 SPOCK2 GPRIN2

6.05e-071996865263338242f95c04690d0795749ccc20b0d19f7a
ToppCellmedial-Epithelial-Alveolar_Epithelial_Type_1|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HSPG2 WNT7A LAMA3 LAMC2 SPOCK2 GPRIN2

6.05e-07199686c11365653c69a5dfb37946231f8af05149a61a71
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RHOBTB3 WNT7A LAMA3 LAMC2 SPOCK2 GPRIN2

6.23e-07200686c6f211bbadd0c9be776c58807249e06764df47dc
ToppCelldistal-3-Epithelial-Alveolar_Epithelial_Type_1|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

WFDC2 WNT7A LAMA3 LAMC2 SPOCK2 GPRIN2

6.23e-07200686ff64454a08ae8d4cc6e8f0392558460020844bbc
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

RHOBTB3 WNT7A LAMA3 LAMC2 SPOCK2 GPRIN2

6.23e-072006865f7e8d8b05c90a10313775f9f126eb4ab0fe4f67
ToppCelldistal-Epithelial-Alveolar_Epithelial_Type_1-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FRAS1 WNT7A LAMA3 LAMC2 SPOCK2 GPRIN2

6.23e-07200686ccd0edd483728279fe15d64be3a39e8636bf2eeb
ToppCellParenchyma_Control_(B.)-Epithelial-TX-AT1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

RHOBTB3 WNT7A LAMA3 LAMC2 SPOCK2 GPRIN2

6.23e-07200686e3a80626941363bfc9d97ef906d38c97080aecb1
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 ERBB4 USH2A LRP1B GPRIN2

2.87e-0614568596712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellAT1-AT2_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

FRAS1 WNT7A LAMA3 LAMC2 SPOCK2

4.94e-0616268557d627259d27f39885bf416d74bcb6656db6e27b
ToppCell3'_v3-Lung-Myeloid_Mac-Intestinal_macrophages|Lung / Manually curated celltypes from each tissue

GPR155 ERBB4 MEGF6 ADAM28 STAB1

6.07e-06169685241644823e6f949aaf4c671d4579721d7ef6b0e5
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 WFDC2 USH2A LRP1B ADAM28

6.07e-0616968512bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 WFDC2 LAMA3 LAMC2 PDLIM4

6.61e-06172685bd73fd3520064d430a153cfdd5c2858b6c184c59
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 WFDC2 LAMA3 LAMC2 PDLIM4

6.61e-0617268547ee78ed3ba6516dad8f12dbf70bca5ed1c60aff
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

WFDC2 WNT7A LAMA3 LAMC2 SPOCK2

6.80e-0617368545808cf69122c16b9d2b5ffa06d15392c55954b7
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

WFDC2 WNT7A LAMA3 LAMC2 SPOCK2

6.80e-061736857fa9dbcb258c3ab974490063951620e2def03db1
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FRAS1 IGFBP5 MEGF6 PRSS12 LTBP1

6.80e-0617368530d67738633493d47f06ae452424382f069b6c0a
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 WFDC2 LAMA3 LAMC2 PDLIM4

6.99e-06174685583955b4db442ba0583e2312af242f050547f9d6
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FRAS1 IGFBP5 MEGF6 PRSS12 LTBP1

6.99e-06174685a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PCSK5 SMYD4 MAZ WNT11 DCAF5

7.19e-061756851d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCellAT1-AT2_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

FRAS1 WNT7A LAMA3 LAMC2 SPOCK2

7.19e-061756859a95ab5c361ebaa8747983c5a0d69025682a19ad
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

WFDC2 LAMA3 LAMC2 SPOCK2 EGFL6

7.19e-06175685442f261a3b2c4d2523f7d4089178f8c79cac2f0f
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PCSK5 SMYD4 MAZ WNT11 DCAF5

7.19e-06175685427a7ee92fe16a90625946492062d37aa0f7235b
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

WFDC2 LAMA3 LAMC2 SPOCK2 EGFL6

7.19e-0617568535fb7735dd3355476fe60404833cb60bd066bcf1
ToppCellControl-Epithelial_alveolar-AT_1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IGFBP5 WFDC2 LAMA3 LAMC2 SPOCK2

7.81e-06178685aa7d43c655df493f1330a5001efaa484e4a19f69
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FRAS1 RHOBTB3 LAMA3 LAMC2 SPOCK2

8.02e-061796854f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

WNT7A LAMA3 LAMC2 SPOCK2 GPRIN2

8.02e-06179685d5e3e7f1cd8f683f39a7416f12af7e766dcbead8
ToppCellAT1_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

HSPG2 LAMA3 LAMC2 SPOCK2 GPRIN2

8.02e-061796851603117b52623663458a977c94bf7f9f6c1114b8
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FRAS1 ERBB4 WFDC2 PRSS12 NEXMIF

8.24e-06180685b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCellAT1_cells-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

WNT7A LAMA3 LAMC2 SPOCK2 GPRIN2

8.24e-06180685e1964002681f80d8d62406b6ee52a01e1829ccf2
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HSPG2 FRAS1 LAMA3 LAMC2 SPOCK2

8.46e-06181685b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellAT1-AT2_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

RHOBTB3 WNT7A LAMA3 SPOCK2 GPRIN2

8.46e-06181685ca23ce4f2c7b684d8ddd0e8619b3b696023d75e3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 RHOBTB3 LAMA3 LAMC2 LRP1B

8.69e-06182685a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ERBB4 IGFBP5 LRRC3B LAMA3 NOTCH2

8.69e-06182685d3a037268f026eb2f84428b1821022503cef7756
ToppCellBasal|World / shred by cell class for mouse tongue

MEGF6 WFDC2 LAMA3 LAMC2 LTBP1

8.93e-06183685c6729a207526ff4aa48176207b9353176f631fea
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCSK5 MEGF6 PRSS12 WNT11 LTBP1

8.93e-061836857eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SMYD4 CILP LTBP1 CAMK1G LRP1B

8.93e-06183685262387ee8d43b96e5f1a77c75124459a506a6172
ToppCelldroplet-Lung-nan-21m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 DPYD IGFBP5 SPOCK2 TNFRSF19

8.93e-06183685b153425ab0df1e5fa9b953e1f6d4e8e3dc6621b0
ToppCelldroplet-Lung-nan-21m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 DPYD IGFBP5 SPOCK2 TNFRSF19

8.93e-0618368519e7be1cfdd111bfb840532a6f7c780345dffccf
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SMYD4 CILP LTBP1 CAMK1G LRP1B

8.93e-06183685c85a707acbcb582912e8ac080a36d05f91cfd7a2
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HSPG2 FRAS1 WFDC2 LAMA3 LAMC2

9.17e-0618468542ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

HSPG2 WNT7A LAMA3 LAMC2 SPOCK2

9.17e-06184685c7073d1b2c4fdb154d87678b92a0629c02116972
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PROK2 SEMA6B TNFRSF1B AGTPBP1 STAB1

9.17e-06184685d1ea2b60fb1ca1a0b809d131310c43903a9e84ce
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

HSPG2 WNT7A LAMA3 LAMC2 SPOCK2

9.17e-061846851ed558a88215b248431c524ea16f13d9022ae98c
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

IGFBP5 MEGF6 PRSS12 LTBP1 LRP1B

9.17e-06184685607b55022de21ddb6a2d75e085df76df7abf6624
ToppCelldroplet-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEGF6 FRS3 ADAM28 PDLIM4 STAB1

9.41e-061856856a85399cfdb9b89683c874e7f046957f9a601dc2
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRAS1 WFDC2 LAMA3 LAMC2 SPOCK2

9.41e-06185685c82eab551f65ecebe6db908eda9f9eb3414693c7
ToppCelldroplet-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEGF6 FRS3 ADAM28 PDLIM4 STAB1

9.41e-0618568564791056cdbb739136dbef08f4b16e2b5427faad
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HSPG2 FRAS1 LAMA3 LAMC2 SPOCK2

9.66e-061866853aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCelldroplet-Kidney-nan-3m-Endothelial-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 IGFBP5 LRRC3B LTBP1 RTP4

9.66e-06186685d72cdbb6d79ab33a5823c42e93c2ba566244f64c
ToppCellControl-Epithelial-ATI|Epithelial / Disease state, Lineage and Cell class

RHOBTB3 WNT7A LAMA3 SPOCK2 GPRIN2

9.91e-061876853a032432f780525f4f4c2a358897d9989b1ecae7
ToppCellwk_08-11-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SEMA6B HSPG2 LRRC3B SPOCK2 TNFRSF1B

9.91e-06187685a27aa97aa6508a3ffe92c2b6bb0511a95650a390
ToppCellT_cells-ISG-high_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

GPR155 WNT7A SPOCK2 RTP4 PML

1.02e-051886856f8946d4710f6e32c937213f99b790b098b8819c
DrugRetrorsine [480-54-6]; Up 200; 11.4uM; HL60; HT_HG-U133A

HSPG2 SPOCK2 LTBP1 BRINP1 ADAM28 GPRIN2 PML

1.83e-061976772129_UP
DrugHydrastine hydrochloride [5936-28-7]; Up 200; 9.6uM; MCF7; HT_HG-U133A

IGFBP5 MEGF6 CGA FRS3 LAMC2 CAMK1G PML

1.83e-061976776011_UP
Drug(+) -Levobunolol hydrochloride [47141-41-3]; Up 200; 12.2uM; MCF7; HT_HG-U133A

STAB2 IGFBP5 CILP LAMC2 SPOCK2 BRINP1 GPRIN2

1.83e-061976773355_UP
DrugNomegestrol acetate [58652-20-3]; Up 200; 10.8uM; PC3; HT_HG-U133A

STAB2 LDB1 ZBTB17 FRS3 LAMC2 GPRIN2 PML

1.89e-061986776362_UP
DrugCapsaicin [404-86-4]; Up 200; 13uM; MCF7; HT_HG-U133A

SEMA6B MEGF6 CILP BRINP1 PML STAB1

2.43e-051966763372_UP
DrugDydrogesterone [152-62-5]; Up 200; 12.8uM; HL60; HT_HG-U133A

STAB2 LDB1 MARCHF2 GPRIN2 PML STAB1

2.50e-051976762156_UP
DrugFludrocortisone acetate [514-36-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A

HSPG2 FRAS1 LAMC2 PML PDLIM4 STAB1

2.50e-051976762328_UP
DrugNifuroxazide [965-52-6]; Up 200; 14.6uM; HL60; HT_HG-U133A

ZBTB17 CILP CGA EGFL6 GPRIN2 PML

2.50e-051976762490_UP
Drug(S)-(-)-Atenolol [93379-54-5]; Up 200; 15uM; HL60; HT_HG-U133A

RHOBTB3 CGA LTBP1 RHO PML PDLIM4

2.57e-051986763067_UP
DrugRitodrine hydrochloride [23239-51-2]; Up 200; 12.4uM; MCF7; HT_HG-U133A

SEMA6B WFDC2 PRSS12 BRINP1 PML STAB1

2.57e-051986765680_UP
DrugEtofylline [519-37-9]; Up 200; 17.8uM; MCF7; HT_HG-U133A

SEMA6B FRAS1 STAB2 SPOCK2 ADAM28 PML

2.57e-051986762256_UP
DrugLobelanidine hydrochloride [6112-86-3]; Up 200; 10.6uM; MCF7; HT_HG-U133A

IGFBP5 WFDC2 PRSS12 BRINP1 GPRIN2 PML

2.57e-051986765500_UP
DrugNifenazone [2139-47-1]; Up 200; 13uM; MCF7; HT_HG-U133A

SEMA6B IGFBP5 LAMC2 BRINP1 PML PDLIM4

2.57e-051986762285_UP
DrugTobramycin [32986-56-4]; Up 200; 8.6uM; HL60; HT_HG-U133A

IGFBP5 CILP CGA LTBP1 GPRIN2 STAB1

2.72e-052006762481_UP
DrugSR 142801

HSPG2 TNFRSF1B RHO

4.72e-0524673CID000219077
Drugpanobinostat

PROK2 FRAS1 LRRC3B WFDC2 PRSS12 NEXMIF RHOBTB3 AS3MT LAMC2 LINGO2 BRINP1 LHX8 ADAM28

1.17e-0413336713ctd:C496932
Drugsphingosine 1-phosphate

LAMA3 LAMC2 S1PR1

1.76e-0437673ctd:C060506
Drugabrine

PROK2 ERBB4 STAB2 WNT11 LAMA3 TNFRSF1B

1.92e-04285676ctd:C496492
DrugChloropyramine hydrochloride [6170-42-9]; Up 200; 12.2uM; PC3; HT_HG-U133A

WFDC2 WNT7A LAMC2 BRINP1 PML

2.27e-041876754589_UP
DrugLeflunomide [75706-12-6]; Up 200; 14.8uM; HL60; HT_HG-U133A

ZBTB17 IGFBP5 WNT7A MUC2 RHO

2.44e-041906752539_UP
DrugMeticrane [1084-65-7]; Up 200; 14.6uM; PC3; HT_HG-U133A

IGFBP5 CLPX GPRIN2 PML PDLIM4

2.56e-041926751792_UP
DrugManNAc-6-P

TSPAN31 TNFRSF19 NOTCH2

2.58e-0442673CID000000898
DrugGW8510; Up 200; 10uM; MCF7; HT_HG-U133A

HSPG2 IGFBP5 RHOBTB3 CGA LAMC2

2.62e-041936757080_UP
DrugFlumethasone [2135-17-3]; Up 200; 9.8uM; MCF7; HT_HG-U133A

MEGF6 WNT7A LAMC2 ADAM28 PML

2.68e-041946753610_UP
DrugNaringin hydrate [11032-30-7]; Up 200; 6.6uM; HL60; HT_HG-U133A

STAB2 IGFBP5 MARCHF2 CGA CAMK1G

2.75e-041956752425_UP
DrugTestosterone propionate [57-85-2]; Up 200; 11.6uM; MCF7; HT_HG-U133A

IGFBP5 CILP LAMC2 SPOCK2 PML

2.75e-041956755636_UP
DrugCarbarsone [121-59-5]; Up 200; 15.4uM; PC3; HT_HG-U133A

PCSK5 PRSS12 RHOBTB3 ADAM28 PML

2.75e-041956753991_UP
DrugPyridoxine hydrochloride [58-56-0]; Up 200; 19.4uM; PC3; HT_HG-U133A

STAB2 ZBTB17 FRS3 S1PR1 NOTCH2

2.75e-041956755813_UP
DrugDehydroisoandosterone 3-acetate [853-23-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A

IGFBP5 CILP SPOCK2 GPRIN2 PML

2.75e-041956756474_UP
DrugFlumethasone [2135-17-3]; Up 200; 9.8uM; PC3; HT_HG-U133A

HSPG2 ERBB4 MAZ PML STAB1

2.75e-041956754272_UP
DrugEthionamide [536-33-4]; Up 200; 24uM; PC3; HT_HG-U133A

HSPG2 ZBTB17 WFDC2 CGA BRINP1

2.75e-041956754593_UP
DrugThalidomide [50-35-1]; Up 200; 15.4uM; MCF7; HT_HG-U133A

ERBB4 STAB2 IGFBP5 LAMC2 PML

2.75e-041956755990_UP
DrugButylparaben [94-26-8]; Up 200; 20.6uM; PC3; HT_HG-U133A

CGA FRS3 CAMK1G MUC2 S1PR1

2.75e-041956754647_UP
DrugSulfachloropyridazine [80-32-0]; Down 200; 14uM; PC3; HT_HG-U133A

IGFBP5 MAZ SPOCK2 S1PR1 PML

2.75e-041956754326_DN
DrugThiocolchicoside [602-41-5]; Up 200; 7uM; MCF7; HT_HG-U133A

HSPG2 ZBTB17 LAMC2 SPOCK2 PML

2.75e-041956752875_UP
DrugPempidine tartrate [546-48-5]; Down 200; 13uM; MCF7; HT_HG-U133A

ZBTB17 IGFBP5 LAMA3 LAMC2 PML

2.81e-041966753832_DN
DrugMetanephrine hydrochloride DL [881-95-8]; Up 200; 17.2uM; MCF7; HT_HG-U133A

HSPG2 STAB2 FRS3 RHO PML

2.81e-041966751515_UP
DrugAscorbic acid [50-81-7]; Up 200; 22.4uM; MCF7; HT_HG-U133A

STAB2 IGFBP5 LAMA3 GPRIN2 PML

2.81e-041966755407_UP
Drugclozapine; Up 200; 10uM; PC3; HT_HG-U133A

WFDC2 BRINP1 MUC2 ADAM28 PML

2.81e-041966754453_UP
Drug6-Furfurylaminopurine [525-79-1]; Down 200; 18.6uM; MCF7; HT_HG-U133A

LDB1 TSPAN31 IGFBP5 LTBP1 PML

2.81e-041966756813_DN
DrugGanciclovir [82410-32-0]; Up 200; 15.6uM; MCF7; HT_HG-U133A

HSPG2 CILP LAMC2 MUC2 PML

2.81e-041966753368_UP
DrugCGX 0596987; Up 200; 20uM; MCF7; HT_HG-U133A

CILP WFDC2 FRS3 GPRIN2 STAB1

2.81e-041966756364_UP
DrugBenzathine benzylpenicillin [5928-84-7]; Up 200; 4.2uM; PC3; HT_HG-U133A

PRSS12 RHOBTB3 BRINP1 MUC2 S1PR1

2.81e-041966754022_UP
DrugDehydroisoandosterone 3-acetate [853-23-6]; Down 200; 12.2uM; PC3; HT_HG-U133A

HSPG2 WFDC2 FRS3 LAMC2 PML

2.81e-041966756673_DN
DrugFamotidine [76824-35-6]; Down 200; 11.8uM; MCF7; HT_HG-U133A

ZBTB17 LAMA3 LAMC2 NOTCH2 GPRIN2

2.81e-041966755011_DN
DrugNorfloxacin [70458-96-7]; Up 200; 12.6uM; MCF7; HT_HG-U133A

IGFBP5 CGA CAMK1G GPRIN2 PML

2.81e-041966755985_UP
DrugProstaglandin E1; Down 200; 10uM; PC3; HT_HG-U133A

WFDC2 FRS3 SPOCK2 NOTCH2 PML

2.81e-041966756571_DN
DrugAmphotericin B [1397-89-3]; Up 200; 4.4uM; HL60; HT_HG-U133A

STAB2 RHOBTB3 SPOCK2 ADAM28 NOTCH2

2.81e-041966752441_UP
Druggenistein; Up 200; 10uM; HL60; HT_HG-U133A

STAB2 CILP WFDC2 USH2A PML

2.81e-041966756194_UP
DrugClemizole hydrochloride [1163-36-6]; Up 200; 11uM; MCF7; HT_HG-U133A

HSPG2 FRAS1 LAMC2 MUC2 PML

2.81e-041966752301_UP
Drugmercuric bromide

PROK2 IGFBP5 LRRC3B WFDC2 PRSS12 NEXMIF RHOBTB3 LAMC2 TNFRSF19 LHX8 ADAM28

2.82e-0410766711ctd:C042720
DrugCyanocobalamin [68-19-9]; Up 200; 3uM; PC3; HT_HG-U133A

ZBTB17 WFDC2 CGA BRINP1 MUC2

2.88e-041976754572_UP
Drugclozapine; Up 200; 10uM; MCF7; HT_HG-U133A

ZBTB17 IGFBP5 MEGF6 GPRIN2 PML

2.88e-041976756988_UP
DrugAmiprilose hydrochloride [60414-06-4]; Up 200; 11.8uM; HL60; HT_HG-U133A

IGFBP5 WFDC2 WNT7A NOTCH2 PML

2.88e-041976753000_UP
DrugCetirizine dihydrochloride [83881-52-1]; Up 200; 8.6uM; HL60; HT_HG-U133A

ZBTB17 CILP FRS3 SPOCK2 PML

2.88e-041976752468_UP
Drug3-Acetylcoumarin [3949-36-8]; Up 200; 21.2uM; MCF7; HT_HG-U133A

MEGF6 PRSS12 LAMC2 EGFL6 PML

2.88e-041976753382_UP
Drug0225151-0000 [351320-15-5]; Up 200; 10uM; PC3; HT_HG-U133A

WFDC2 RHOBTB3 SPOCK2 GPRIN2 PML

2.88e-041976756389_UP
DrugScopolamine hydrochloride [55-16-3]; Up 200; 11.8uM; MCF7; HT_HG-U133A

FRAS1 IGFBP5 WFDC2 SPOCK2 GPRIN2

2.88e-041976753357_UP
Drug(d,l)-Tetrahydroberberine [522-97-4]; Up 200; 11.8uM; HL60; HT_HG-U133A

STAB2 RHOBTB3 FRS3 RHO PML

2.88e-041976752163_UP
DrugPhentolamine hydrochloride [73-05-2]; Up 200; 12.6uM; HL60; HT_HG-U133A

IGFBP5 PRSS12 RHOBTB3 LAMC2 PML

2.88e-041976752362_UP
DrugChlorogenic acid [327-97-9]; Down 200; 11.2uM; PC3; HT_HG-U133A

STAB2 WFDC2 CGA BRINP1 PML

2.88e-041976754024_DN
DrugGuaifenesin [93-14-1]; Up 200; 20.2uM; MCF7; HT_HG-U133A

IGFBP5 MEGF6 SPOCK2 RHO PML

2.88e-041976753897_UP
DrugMyosmine [532-12-7]; Up 200; 27.4uM; MCF7; HT_HG-U133A

SEMA6B BRINP1 ADAM28 GPRIN2 PML

2.88e-041976756055_UP
DrugMeptazinol hydrochloride [59263-76-2]; Down 200; 14.8uM; PC3; HT_HG-U133A

PRSS12 FRS3 LAMC2 NOTCH2 PDLIM4

2.88e-041976754188_DN
DrugProtriptyline hydrochloride [1225-55-4]; Up 200; 13.4uM; HL60; HT_HG-U133A

FRAS1 IGFBP5 WFDC2 LTBP1 PDLIM4

2.88e-041976753119_UP
DrugFursultiamine Hydrochloride [2105-43-3]; Up 200; 9.2uM; HL60; HT_HG-U133A

HSPG2 IGFBP5 SPOCK2 LTBP1 PML

2.95e-041986752929_UP
DrugCotinine (-) [486-56-6]; Up 200; 22.6uM; PC3; HT_HG-U133A

PCSK5 HSPG2 FRS3 BRINP1 CAMK1G

2.95e-041986754650_UP
DrugTiabendazole [148-79-8]; Up 200; 19.8uM; HL60; HT_HG-U133A

CILP PRSS12 LTBP1 GPRIN2 PML

2.95e-041986752479_UP
DrugBenzthiazide [91-33-8]; Down 200; 9.2uM; HL60; HT_HG-U133A

HSPG2 BRINP1 MUC2 ADAM28 PML

2.95e-041986752989_DN
DrugHydralazine hydrochloride [304-20-1]; Down 200; 20.4uM; PC3; HT_HG-U133A

LDB1 IGFBP5 WFDC2 FRS3 PML

2.95e-041986754282_DN
DrugZoxazolamine [61-80-3]; Up 200; 23.8uM; MCF7; HT_HG-U133A

SEMA6B LAMC2 SPOCK2 GPRIN2 PML

2.95e-041986755390_UP
DrugPancuronium bromide [15500-66-0]; Up 200; 5.4uM; HL60; HT_HG-U133A

ZBTB17 LTBP1 EGFL6 GPRIN2 PML

2.95e-041986752909_UP
DrugLevopropoxyphene napsylate [5714-90-9]; Up 200; 7.4uM; MCF7; HT_HG-U133A

HSPG2 IGFBP5 WFDC2 LAMC2 PML

2.95e-041986755503_UP
DrugFluphenazine dihydrochloride [146-56-5]; Down 200; 7.8uM; PC3; HT_HG-U133A

ZBTB17 RHOBTB3 MAZ NOTCH2 PDLIM4

2.95e-041986755880_DN
Drug2-propylpentanoic acid; Up 200; 1000uM; HL60; HT_HG-U133A

IGFBP5 WFDC2 RHOBTB3 CGA SPOCK2

2.95e-041986756168_UP
DrugTrazodone hydrochloride [25332-39-2]; Up 200; 9.8uM; HL60; HT_HG-U133A

CGA SPOCK2 ADAM28 PML PDLIM4

2.95e-041986752379_UP
DrugChlorpropamide [94-20-2]; Up 200; 14.4uM; PC3; HT_HG-U133A

STAB2 IGFBP5 FRS3 S1PR1 GPRIN2

2.95e-041986756291_UP
DrugButirosin disulfate salt [51022-98-1]; Up 200; 5.4uM; HL60; HT_HG-U133A

PCSK5 CGA FRS3 LTBP1 PML

2.95e-041986752518_UP
DrugSuprofen [40828-46-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A

SEMA6B HSPG2 LAMC2 SPOCK2 PML

2.95e-041986753343_UP
Drugvaldecoxib; Down 200; 10uM; PC3; HT_HG-U133A

SEMA6B IGFBP5 S1PR1 PML PDLIM4

2.95e-041986756378_DN
DrugBenzocaine [94-09-7]; Up 200; 24.2uM; MCF7; HT_HG-U133A

STAB2 MAZ CGA LAMC2 GPRIN2

3.02e-041996752822_UP
DrugTrifluridine [70-00-8]; Up 200; 13.6uM; HL60; HT_HG-U133A

CILP PRSS12 BRINP1 PML STAB1

3.02e-041996756136_UP
DrugThyroxine (L) [51-48-9]; Up 200; 5.2uM; MCF7; HT_HG-U133A

IGFBP5 FRS3 LAMA3 SPOCK2 PML

3.02e-041996753249_UP
Drug(-) -Levobunolol hydrochloride [27912-14-7]; Down 200; 12.2uM; PC3; HT_HG-U133A

HSPG2 STAB2 MAZ CGA GPRIN2

3.02e-041996754016_DN
DrugSulmazole [73384-60-8]; Up 200; 14uM; HL60; HT_HG-U133A

HSPG2 ZBTB17 MARCHF2 LTBP1 PML

3.02e-041996752153_UP
DrugBethanechol chloride [590-63-6]; Up 200; 20.4uM; MCF7; HT_HG-U133A

HSPG2 IGFBP5 BRINP1 GPRIN2 PML

3.02e-041996755539_UP
DrugMetoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Up 200; 5.8uM; HL60; HT_HG-U133A

STAB2 WNT7A CGA BRINP1 RHO

3.02e-041996752543_UP
DrugYohimbinic acid monohydrate [27801-27-2]; Down 200; 11.2uM; HL60; HT_HG-U133A

HSPG2 LDB1 IGFBP5 ADAM28 PML

3.02e-041996752147_DN
DrugCefotaxime sodium salt [64485-93-4]; Up 200; 8.4uM; PC3; HT_HG-U133A

LDB1 TSPAN31 IGFBP5 LTBP1 PML

3.09e-042006755830_UP
Drugnordihydroguaiaretic acid; Up 200; 1uM; PC3; HT_HG-U133A

CILP FRS3 S1PR1 ADAM28 STAB1

3.09e-042006754447_UP
DrugS(+)-Terguride [37686-84-3]; Up 200; 11.8uM; MCF7; HT_HG-U133A

IGFBP5 MEGF6 CGA LAMC2 PML

3.09e-042006755400_UP
DrugBenzthiazide [91-33-8]; Up 200; 9.2uM; HL60; HT_HG-U133A

SEMA6B PCSK5 PRSS12 WNT7A ADAM28

3.09e-042006752989_UP
DrugMidecamycin [35457-80-8]; Up 200; 5uM; MCF7; HT_HG-U133A

HSPG2 MEGF6 LAMA3 TNFRSF1B PML

3.09e-042006751526_UP
DrugNitrofural [59-87-0]; Up 200; 20.2uM; HL60; HT_HG-U133A

WFDC2 RHOBTB3 FRS3 NOTCH2 GPRIN2

3.09e-042006752459_UP
DrugAC1L1C2F

HSPG2 LAMA3 LAMC2 NOTCH2

3.13e-04110674CID000001711
Diseaseretinitis pigmentosa (implicated_via_orthology)

EYS USH2A AGTPBP1 RHO

3.62e-0727654DOID:10584 (implicated_via_orthology)
DiseaseJunctional epidermolysis bullosa

LAMA3 LAMC2

1.43e-053652cv:C0079301
DiseaseJunctional epidermolysis bullosa gravis of Herlitz

LAMA3 LAMC2

1.43e-053652cv:C0079683
DiseaseEPIDERMOLYSIS BULLOSA, JUNCTIONAL 1B, SEVERE

LAMA3 LAMC2

1.43e-053652226700
DiseaseEpidermolysis Bullosa Progressiva

LAMA3 LAMC2

2.86e-054652C0079297
DiseaseHerlitz Disease

LAMA3 LAMC2

2.86e-054652C0079683
Diseaseresponse to radiation, pain

RFFL EGFL6

2.86e-054652EFO_0003843, GO_0009314
DiseaseAdult junctional epidermolysis bullosa (disorder)

LAMA3 LAMC2

4.76e-055652C0268374
DiseaseEPIDERMOLYSIS BULLOSA, JUNCTIONAL, LOCALISATA VARIANT (disorder)

LAMA3 LAMC2

4.76e-055652C2608084
Diseasejunctional epidermolysis bullosa non-Herlitz type (implicated_via_orthology)

LAMA3 LAMC2

4.76e-055652DOID:0060738 (implicated_via_orthology)
Diseaseresponse to platinum based chemotherapy, cytotoxicity measurement

FRAS1 EYS

4.76e-055652EFO_0004647, EFO_0006952
DiseaseJunctional Epidermolysis Bullosa

LAMA3 LAMC2

7.13e-056652C0079301
Diseasejunctional epidermolysis bullosa (is_implicated_in)

LAMA3 LAMC2

9.96e-057652DOID:3209 (is_implicated_in)
Diseaseneuroticism measurement

PROK2 ERBB4 AS3MT PHF6 LINGO2 BRINP1 LHX8 DCAF5 STAB1

1.64e-04909659EFO_0007660
Diseaselung adenocarcinoma (is_implicated_in)

ERBB4 LRP1B ADAM28

1.75e-0449653DOID:3910 (is_implicated_in)
Diseasehomostachydrine measurement

EYS ERBB4

3.67e-0413652EFO_0021164
Diseasebody weight

PCSK5 DPYD EYS ERBB4 NEXMIF RTTN LTBP1 LINGO2 BRINP1 LRP1B

4.13e-0412616510EFO_0004338
Diseasemigraine disorder, endometriosis

EYS ERBB4 LRP1B

5.68e-0473653EFO_0001065, MONDO_0005277
DiseaseRetinitis pigmentosa

EYS USH2A RHO

5.91e-0474653cv:C0035334
Diseasefeeling "fed-up" measurement

CTU2 ERBB4 DCAF5

6.39e-0476653EFO_0009588
Diseasevisceral adipose tissue measurement

DPYD ERBB4 IGFBP5 AS3MT LINGO2 LHX8

6.66e-04481656EFO_0004765
Diseasewellbeing measurement

ERBB4 SPOCK2 LINGO2 BRINP1 LHX8 DCAF5 STAB1

8.11e-04692657EFO_0007869
Diseasecognitive function measurement

DPYD ERBB4 LRRC3B LTBP1 LINGO2 BRINP1 MUC2 USH2A LRP1B STAB1

1.11e-0314346510EFO_0008354
Diseasegeneralized anxiety disorder

LHX8 VWDE

1.17e-0323652EFO_1001892
DiseaseBreast Carcinoma

DPYD CTU2 ERBB4 IGFBP5 LRRC3B NOTCH2

1.19e-03538656C0678222
DiseaseDisorder of eye

FRAS1 EYS USH2A RHO

1.24e-03212654C0015397
Diseasediffuse plaque measurement

PCSK5 EYS ERBB4 RHOBTB3 BRINP1 LRP1B AGTPBP1

1.37e-03758657EFO_0010699
Diseasesystemic mastocytosis

EYS MEGF6

1.39e-0325652MONDO_0016586
DiseaseCFTR mutation carrier status

PCSK5 BRINP1

1.39e-0325652EFO_0021794
DiseaseFEV/FEC ratio

PCSK5 HSPG2 FRAS1 MEGF6 WNT7A LAMC2 LTBP1 BRINP1 PML

1.43e-031228659EFO_0004713
DiseaseRetinitis Pigmentosa

EYS USH2A RHO

1.59e-03104653C0035334
Diseasecongestive heart failure (is_implicated_in)

PHF6 TNFRSF1B

1.62e-0327652DOID:6000 (is_implicated_in)
Diseaselumbar disc degeneration

EYS SPOCK2

1.74e-0328652EFO_0004994
Diseaselung small cell carcinoma (is_implicated_in)

LAMA3 LAMC2

1.74e-0328652DOID:5409 (is_implicated_in)
Diseaseanxiety measurement

DPYD AS3MT BRINP1

1.77e-03108653EFO_0009863
Diseasecolorectal cancer, overall survival

ERBB4 TNFRSF19

1.87e-0329652EFO_0000638, MONDO_0005575
Diseasecolorectal cancer (implicated_via_orthology)

DPYD NOTCH2

2.00e-0330652DOID:9256 (implicated_via_orthology)
Diseaseosteoporosis (is_implicated_in)

TNFRSF1B PDLIM4

2.13e-0331652DOID:11476 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
GGCSGPKDTDCFACM

ERBB4

236

Q15303
NSKGVCEATCEPGCK

EGFL6

56

Q8IUX8
GESGMCDSKCCHPSN

CCDC62

506

Q6P9F0
MPSCGACTCGAAAVR

CLPX

1

O76031
IPCVIGGNNSCAMCS

BRINP1

426

O60477
ECDLPEMCNGKSGNC

ADAM28

471

Q9UKQ2
CGMVCPTSDLCVGGC

DPYD

126

Q12882
TCAKACPHMATCGNV

AGTPBP1

566

Q9UPW5
RNPDGCLKCFCMGVS

HSPG2

916

P98160
CMLTTICCGKNPLGD

RHO

316

P08100
SCMCPEGKAGLLCHL

NOTCH2

361

Q04721
CLDKIGGFTCLCMPG

NOTCH2

471

Q04721
CMDGVNTFSCLCLPG

NOTCH2

926

Q04721
GGVCPQKMAAAVTCS

PRSS12

256

P56730
ACMGPAPSHCTGCKK

FRAS1

661

Q86XX4
CAANDGKGPCSHMCL

LRP1B

1531

Q9NZR2
VGQCHASPCSLMKCG

EYS

2606

Q5T1H1
ASPCSLMKCGNGGTC

EYS

2611

Q5T1H1
ALSSMCSGPSGVCQC

LAMA3

691

Q16787
MSVGCACPGCSSKSF

LDB1

1

Q86U70
MTTGDCCHLPGSLCD

MARCHF2

1

Q9P0N8
SIPETSCCSCSMGNG

GPR155

586

Q7Z3F1
MECKGPGAKNCTLCP

PCSK5

1676

Q92824
PCMNGGQCSSRDKCQ

LTBP1

406

Q14766
PGSITFMPNGCCKTC

MUC2

5051

Q02817
KDCCGSEMACETPNA

DCAF5

881

Q96JK2
CELCNKGTGEVCPMA

MAZ

421

P56270
SMASGSGCPPGKCVC

LHX8

61

Q68G74
FMGSTIGCPARCECS

LINGO2

21

Q7L985
ELVKEPGCGCCMTCA

IGFBP5

46

P24593
ASMCPKGCLCSSSGG

LRRC3B

31

Q96PB8
GFCPSQCSCSLHIMG

LRIT1

21

Q9P2V4
MHQGSLAAGPCGCCS

CAMK1G

406

Q96NX5
GAPILQCMGCCFSRA

CGA

46

P01215
KDSQCGGGMCCAVSI

PROK2

36

Q9HC23
MGSCCSCLNRDSVPD

FRS3

1

O43559
MKSRCVPDAAGGCCG

AS3MT

356

Q9HBK9
CFKFNGCAAPMQCLG

FBXO47

146

Q5MNV8
PADKCRACNCNPMGS

LAMC2

566

Q13753
MQSLRRPSCCGCSGA

GPRIN2

441

O60269
MSCCKCPSGDSAGKF

S1PR1

326

P21453
AGDSGPRCLLCMCAL

CTU2

381

Q2VPK5
DSCCPAGIFQAMCLL

RHOBTB3

481

O94955
CFPCCRGSGKNNMGA

POTEA

31

Q6S8J7
GKCQMSLSGPQCLCV

MUC17

4356

Q685J3
SFGEDCAQMCQCPGE

MEGF6

1166

O75095
ACTLGICGQGLKSCM

RTP4

156

Q96DX8
MFCTCAGLSATCPAL

RTTN

1776

Q86VV8
HCQMCECDSLGTLPG

USH2A

896

O75445
EAFCCNSCGAPMQGD

SMYD4

616

Q8IYR2
CMTCSSQVGNGPRLC

RFFL

71

Q8WZ73
GDCLMQPSRTCLGCF

NEXMIF

136

Q5QGS0
LCSGCLEASGMQCPI

PML

76

P29590
PECFMCSDCGLNLKQ

PDLIM4

276

P50479
MGQDCTACDLTCPMG

CILP

196

O75339
NAGIKCLDSMCCFPE

ATP11B

1111

Q9Y2G3
SQCPGQMKCCRNGCG

WFDC2

101

Q14508
QKSICDPTCMNGGKC

VWDE

1486

Q8N2E2
EPGCTMGICSSCNFA

RNF14

321

Q9UBS8
CCGTPIEKLDGCNKM

RNF14

406

Q9UBS8
GCMKNCIGSQDPYCG

SEMA6B

531

Q9H3T3
RGTKLMCSLCHCPGA

PHF6

76

Q8IWS0
MVCGGFACSKNALCA

TSPAN31

1

Q12999
MEQGCCKGFFGPDCT

STAB1

716

Q9NY15
PGVGCSMTDICKSDN

STAB2

316

Q8WWQ8
GEKPCQCVMCGKAFT

ZBTB17

526

Q13105
CVPCNQCGPGMELSK

TNFRSF19

46

Q9NS68
KTSNGSDSCDLMCCG

WNT11

301

O96014
KTAPQASGCDLMCCG

WNT7A

296

O00755
YDQTAQMCCSKCSPG

TNFRSF1B

46

P20333
SCPSCGQTCHMSGKL

PRR11

141

Q96HE9
CKPCHMAQLASVCGS

SPOCK2

136

Q92563