Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionserine-type peptidase activity

BMP1 PRSS29P RELN PRSS12 LPA PLG F2

1.65e-05207787GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

BMP1 PRSS29P RELN PRSS12 LPA PLG F2

1.92e-05212787GO:0017171
GeneOntologyMolecularFunctionprotein kinase activator activity

TAOK2 LGALS9C ABI1 TAOK1 MLST8 NEK9

2.58e-05149786GO:0030295
GeneOntologyMolecularFunctionkinase activator activity

TAOK2 LGALS9C ABI1 TAOK1 MLST8 NEK9

3.71e-05159786GO:0019209
GeneOntologyMolecularFunctiontaurine:sodium symporter activity

SLC6A6 SLC6A11

4.51e-053782GO:0005369
GeneOntologyMolecularFunctionserine-type endopeptidase activity

BMP1 PRSS29P PRSS12 LPA PLG F2

9.98e-05190786GO:0004252
GeneOntologyMolecularFunctiontaurine transmembrane transporter activity

SLC6A6 SLC6A11

1.49e-045782GO:0005368
GeneOntologyMolecularFunctiongamma-aminobutyric acid:sodium:chloride symporter activity

SLC6A6 SLC6A11

2.24e-046782GO:0005332
GeneOntologyMolecularFunctionprotein serine/threonine kinase activator activity

TAOK2 LGALS9C TAOK1 MLST8

2.47e-0478784GO:0043539
GeneOntologyMolecularFunctionprotein kinase regulator activity

TAOK2 LGALS9C ABI1 TAOK1 MLST8 NEK9

5.29e-04259786GO:0019887
GeneOntologyMolecularFunctiongamma-aminobutyric acid transmembrane transporter activity

SLC6A6 SLC6A11

5.33e-049782GO:0015185
GeneOntologyMolecularFunctionprotein serine kinase activity

TAOK2 CDK20 PRKCE TAOK1 TSSK4 NEK9 MAP3K19

5.41e-04363787GO:0106310
GeneOntologyMolecularFunctionkinase activity

TAOK2 CDK20 PRKCE TAOK1 NME9 CLP1 TSSK4 NEK9 MMD2 MAP3K19

7.60e-047647810GO:0016301
GeneOntologyMolecularFunctionpeptidase activity

MEP1B BMP1 PRSS29P RELN PRSS12 LPA USP32 PLG F2

9.98e-04654789GO:0008233
GeneOntologyMolecularFunctionenzyme activator activity

TAOK2 LGALS9C ABI1 FN1 PRKCE TAOK1 MLST8 NEK9 ARF4

1.02e-03656789GO:0008047
GeneOntologyMolecularFunctionkinase regulator activity

TAOK2 LGALS9C ABI1 TAOK1 MLST8 NEK9

1.24e-03305786GO:0019207
GeneOntologyMolecularFunctionendopeptidase activity

MEP1B BMP1 PRSS29P PRSS12 LPA PLG F2

1.45e-03430787GO:0004175
GeneOntologyMolecularFunctionmonocarboxylate:sodium symporter activity

SLC6A6 SLC6A11

1.53e-0315782GO:0140161
GeneOntologyMolecularFunctionprotein antigen binding

LPA PLG

1.74e-0316782GO:1990405
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

TAOK2 CDK20 PRKCE TAOK1 CLP1 TSSK4 NEK9 MMD2 MAP3K19

1.75e-03709789GO:0016773
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

TAOK2 CDK20 PRKCE TAOK1 TSSK4 NEK9 MAP3K19

1.79e-03446787GO:0004674
GeneOntologyMolecularFunctionsodium:chloride symporter activity

SLC6A6 SLC6A11

1.97e-0317782GO:0015378
GeneOntologyMolecularFunctionprotein kinase activity

TAOK2 CDK20 PRKCE TAOK1 TSSK4 NEK9 MMD2 MAP3K19

2.34e-03600788GO:0004672
GeneOntologyMolecularFunctionsecondary active monocarboxylate transmembrane transporter activity

SLC6A6 SLC6A11

2.47e-0319782GO:0015355
GeneOntologyMolecularFunctionmonoatomic anion:sodium symporter activity

SLC6A6 SLC6A11

2.47e-0319782GO:0015373
GeneOntologyMolecularFunctionapolipoprotein binding

LPA PLG

2.73e-0320782GO:0034185
GeneOntologyMolecularFunctionmolecular function activator activity

TAOK2 LGALS9C BMP1 RELN ABI1 FN1 PRKCE TAOK1 MLST8 F2 NEK9 ARF4

2.87e-0312337812GO:0140677
GeneOntologyMolecularFunctiontau-protein kinase activity

TAOK2 TAOK1

3.31e-0322782GO:0050321
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

TAOK2 CDK20 PRKCE TAOK1 NME9 CLP1 TSSK4 NEK9 MMD2 MAP3K19

3.46e-039387810GO:0016772
GeneOntologyMolecularFunctionchloride:monoatomic cation symporter activity

SLC6A6 SLC6A11

3.61e-0323782GO:0015377
GeneOntologyMolecularFunctionamino acid:sodium symporter activity

SLC6A6 SLC6A11

3.61e-0323782GO:0005283
GeneOntologyMolecularFunctionmonoatomic anion:monoatomic cation symporter activity

SLC6A6 SLC6A11

4.61e-0326782GO:0015296
GeneOntologyMolecularFunctionMAP kinase kinase kinase activity

TAOK2 MAP3K19

4.96e-0327782GO:0004709
GeneOntologyMolecularFunctionmRNA 3'-UTR AU-rich region binding

TIA1 TIAL1

5.71e-0329782GO:0035925
GeneOntologyMolecularFunctionamino acid:monoatomic cation symporter activity

SLC6A6 SLC6A11

5.71e-0329782GO:0005416
GeneOntologyBiologicalProcessnegative regulation of fibrinolysis

LPA PLG F2

1.84e-0514783GO:0051918
GeneOntologyBiologicalProcessregulation of fibrinolysis

LPA PLG F2

4.83e-0519783GO:0051917
GeneOntologyBiologicalProcesspositive regulation of stress-activated protein kinase signaling cascade

TAOK2 TAOK1 KLHDC10

1.27e-0426783GO:0070304
GeneOntologyBiologicalProcesspositive regulation of stress-activated MAPK cascade

TAOK2 TAOK1 KLHDC10

1.27e-0426783GO:0032874
GeneOntologyBiologicalProcesspositive regulation of fibrinolysis

LPA PLG

1.40e-045782GO:0051919
GeneOntologyBiologicalProcesspositive regulation of wound healing

LPA PRKCE PLG F2

1.69e-0473784GO:0090303
GeneOntologyBiologicalProcessfibrinolysis

LPA PLG F2

1.77e-0429783GO:0042730
GeneOntologyBiologicalProcessmuscle cell cellular homeostasis

TRIM32 LPA PLG

2.17e-0431783GO:0046716
GeneOntologyBiologicalProcesspositive regulation of hemostasis

LPA PLG F2

2.17e-0431783GO:1900048
GeneOntologyBiologicalProcesspositive regulation of blood coagulation

LPA PLG F2

2.17e-0431783GO:0030194
GeneOntologyBiologicalProcesspositive regulation of coagulation

LPA PLG F2

2.86e-0434783GO:0050820
GeneOntologyBiologicalProcesstrans-synaptic signaling by BDNF, modulating synaptic transmission

LPA PLG

2.93e-047782GO:0099183
GeneOntologyBiologicalProcessnegative regulation of canonical Wnt signaling pathway

TLE1 TLE2 TLE3 TLE4 TNN

2.96e-04154785GO:0090090
GeneOntologyBiologicalProcesstrans-synaptic signaling by BDNF

LPA PLG

3.90e-048782GO:0099191
GeneOntologyBiologicalProcessalkanesulfonate transmembrane transport

SLC6A6 SLC6A11

3.90e-048782GO:0042918
GeneOntologyBiologicalProcesstaurine transmembrane transport

SLC6A6 SLC6A11

3.90e-048782GO:0015734
GeneOntologyBiologicalProcesspositive regulation of lipid metabolic process

RGN PRKCE ADGRF5 MLST8 F2

4.06e-04165785GO:0045834
GeneOntologyBiologicalProcesspositive regulation of response to wounding

LPA PRKCE PLG F2

4.28e-0493784GO:1903036
GeneOntologyCellularComponentbeta-catenin-TCF complex

TLE1 TLE3 TLE4

1.29e-0513763GO:1990907
GeneOntologyCellularComponentcollagen-containing extracellular matrix

LGALS9C BMP1 RELN FN1 LPA TNN LOXL4 DMBT1 PLG F2

2.15e-055307610GO:0062023
GeneOntologyCellularComponentexternal encapsulating structure

LGALS9C BMP1 RELN FN1 LPA TNN LOXL4 DMBT1 PLG F2 PKHD1L1

2.47e-056587611GO:0030312
GeneOntologyCellularComponentextracellular matrix

LGALS9C BMP1 RELN FN1 LPA TNN LOXL4 DMBT1 PLG F2

1.28e-046567610GO:0031012
MousePhenoabnormal mammary gland connective tissue morphology

LPA PLG

2.20e-052662MP:0009507
MousePhenoectropion

LPA PLG

2.20e-052662MP:0006164
MousePhenoesophageal ulcer

LPA PLG

2.20e-052662MP:0004547
MousePhenoduodenal ulcer

LPA PLG

2.20e-052662MP:0003273
MousePhenoperianal ulcer

LPA PLG

2.20e-052662MP:0005035
MousePhenoabsent cornea epithelium

LPA PLG

6.57e-053662MP:0020856
MousePhenoincreased circulating fibrinogen level

LPA PLG

1.31e-044662MP:0012331
MousePhenoproctitis

LPA PLG

1.31e-044662MP:0003305
DomainGroucho_enhance

TLE1 TLE2 TLE3 TLE4

1.26e-095764IPR009146
DomainTLE_N

TLE1 TLE2 TLE3 TLE4

1.26e-095764PF03920
DomainGroucho/TLE_N

TLE1 TLE2 TLE3 TLE4

1.26e-095764IPR005617
DomainKringle-like

FN1 PRSS12 LPA PLG F2

1.80e-0732765IPR013806
DomainWD40_repeat_CS

WDR38 LRWD1 TLE1 TLE2 TLE3 TLE4 FBXW2 MLST8

3.38e-07164768IPR019775
DomainKringle

PRSS12 LPA PLG F2

5.79e-0717764IPR000001
DomainKringle_CS

PRSS12 LPA PLG F2

5.79e-0717764IPR018056
DomainKRINGLE_2

PRSS12 LPA PLG F2

5.79e-0717764PS50070
DomainKringle

PRSS12 LPA PLG F2

5.79e-0717764PF00051
DomainKRINGLE_1

PRSS12 LPA PLG F2

5.79e-0717764PS00021
DomainKR

PRSS12 LPA PLG F2

5.79e-0717764SM00130
DomainWD40

WDR38 LRWD1 TLE1 TLE2 TLE3 TLE4 FBXW2 MLST8

1.03e-05259768PF00400
DomainWD40

WDR38 LRWD1 TLE1 TLE2 TLE3 TLE4 FBXW2 MLST8

1.31e-05268768SM00320
DomainWD40_repeat

WDR38 LRWD1 TLE1 TLE2 TLE3 TLE4 FBXW2 MLST8

1.46e-05272768IPR001680
DomainWD_REPEATS_1

WDR38 LRWD1 TLE1 TLE2 TLE3 TLE4 FBXW2 MLST8

1.71e-05278768PS00678
DomainWD_REPEATS_2

WDR38 LRWD1 TLE1 TLE2 TLE3 TLE4 FBXW2 MLST8

1.76e-05279768PS50082
DomainWD_REPEATS_REGION

WDR38 LRWD1 TLE1 TLE2 TLE3 TLE4 FBXW2 MLST8

1.76e-05279768PS50294
DomainWD40_repeat_dom

WDR38 LRWD1 TLE1 TLE2 TLE3 TLE4 FBXW2 MLST8

2.75e-05297768IPR017986
DomainCRYSTALLIN_BETA_GAMMA

CRYBG2 CRYGS CRYBG1

2.84e-0515763PS50915
DomainCrystall

CRYBG2 CRYGS CRYBG1

2.84e-0515763PF00030
DomainBeta/gamma_crystallin

CRYBG2 CRYGS CRYBG1

2.84e-0515763IPR001064
DomainXTALbg

CRYBG2 CRYGS CRYBG1

2.84e-0515763SM00247
DomainG_crystallin-rel

CRYBG2 CRYGS CRYBG1

5.06e-0518763IPR011024
Domain-

WDR38 LRWD1 TLE1 TLE2 TLE3 TLE4 FBXW2 MLST8

6.17e-053337682.130.10.10
DomainWD40/YVTN_repeat-like_dom

WDR38 LRWD1 TLE1 TLE2 TLE3 TLE4 FBXW2 MLST8

6.43e-05335768IPR015943
DomainSRCR

PRSS12 LOXL4 DMBT1

8.17e-0521763PF00530
DomainSR

PRSS12 LOXL4 DMBT1

1.40e-0425763SM00202
Domain-

PRSS12 LOXL4 DMBT1

1.40e-04257633.10.250.10
DomainSRCR_1

PRSS12 LOXL4 DMBT1

1.57e-0426763PS00420
DomainSRCR_2

PRSS12 LOXL4 DMBT1

1.57e-0426763PS50287
DomainSRCR-like_dom

PRSS12 LOXL4 DMBT1

1.57e-0426763IPR017448
DomainSRCR

PRSS12 LOXL4 DMBT1

1.77e-0427763IPR001190
DomainPrefoldin

TLE1 TLE2 TLE3 TLE4

2.11e-0472764IPR009053
DomainPeptidase_M12A

MEP1B BMP1

2.43e-046762IPR001506
DomainAstacin

MEP1B BMP1

2.43e-046762PF01400
DomainEGF_3

MEP1B BMP1 FAT4 RELN TNN ADGRE4P

3.90e-04235766PS50026
DomainEGF

MEP1B BMP1 FAT4 RELN TNN ADGRE4P

3.90e-04235766SM00181
DomainEGF-like_dom

MEP1B BMP1 FAT4 RELN TNN ADGRE4P

5.30e-04249766IPR000742
DomainEGF_1

MEP1B BMP1 FAT4 RELN FN1 TNN

6.01e-04255766PS00022
DomainSer/Thr_kinase_AS

TAOK2 CDK20 PRKCE TAOK1 TSSK4 NEK9 MAP3K19

6.20e-04357767IPR008271
DomainS_TKc

TAOK2 CDK20 PRKCE TAOK1 TSSK4 NEK9 MAP3K19

6.41e-04359767SM00220
DomainPROTEIN_KINASE_ST

TAOK2 CDK20 PRKCE TAOK1 TSSK4 NEK9 MAP3K19

6.73e-04362767PS00108
DomainEGF-like_CS

MEP1B BMP1 FAT4 RELN FN1 TNN

6.79e-04261766IPR013032
DomainTRYPSIN_HIS

PRSS12 LPA PLG F2

8.25e-04103764IPR018114
DomainPkinase

TAOK2 CDK20 PRKCE TAOK1 TSSK4 NEK9 MAP3K19

9.08e-04381767PF00069
DomainTRYPSIN_SER

PRSS12 LPA PLG F2

9.19e-04106764PS00135
DomainTRYPSIN_HIS

PRSS12 LPA PLG F2

9.52e-04107764PS00134
DomainPeptidase_S1A

PRSS12 LPA PLG F2

1.17e-03113764IPR001314
DomainTRYPSIN_DOM

PRSS12 LPA PLG F2

1.24e-03115764PS50240
DomainTryp_SPc

PRSS12 LPA PLG F2

1.33e-03117764SM00020
DomainTrypsin

PRSS12 LPA PLG F2

1.50e-03121764PF00089
DomainTrypsin_dom

PRSS12 LPA PLG F2

1.50e-03121764IPR001254
DomainPeptidase_S1_PA

PRSS12 LPA PLG F2

1.59e-03123764IPR009003
DomainNA_NEUROTRAN_SYMP_2

SLC6A6 SLC6A11

2.40e-0318762PS00754
DomainPROTEIN_KINASE_ATP

TAOK2 CDK20 PRKCE TAOK1 TSSK4 NEK9 MAP3K19

2.63e-03459767PS00107
DomainSNF

SLC6A6 SLC6A11

2.67e-0319762PF00209
DomainNA_NEUROTRAN_SYMP_1

SLC6A6 SLC6A11

2.67e-0319762PS00610
DomainNA_NEUROTRAN_SYMP_3

SLC6A6 SLC6A11

2.67e-0319762PS50267
DomainNa/ntran_symport

SLC6A6 SLC6A11

2.67e-0319762IPR000175
DomainProt_kinase_dom

TAOK2 CDK20 PRKCE TAOK1 TSSK4 NEK9 MAP3K19

3.73e-03489767IPR000719
DomainPROTEIN_KINASE_DOM

TAOK2 CDK20 PRKCE TAOK1 TSSK4 NEK9 MAP3K19

3.89e-03493767PS50011
DomainRRM_dom_euk

TIA1 TIAL1

3.91e-0323762IPR003954
DomainRRM_1

TIA1 TIAL1

3.91e-0323762SM00361
DomainProtein_kinase_ATP_BS

TAOK2 CDK20 PRKCE TAOK1 TSSK4 MAP3K19

4.45e-03379766IPR017441
DomainEGF_2

MEP1B BMP1 FAT4 RELN TNN

4.51e-03265765PS01186
DomainRicin_B_lectin

CRYBG2 CRYBG1

4.61e-0325762PF00652
DomainG-protein_beta_WD-40_rep

WDR38 FBXW2 MLST8

5.03e-0385763IPR020472
DomainEGF_CA

BMP1 FAT4 ADGRE4P

5.20e-0386763PF07645
Domain-

FN1 CD300LF BTNL3 TNN ADGRF5 EXOC2 IL1RL2 PKHD1L1

5.45e-036637682.60.40.10
DomainRICIN

CRYBG2 CRYBG1

5.77e-0328762SM00458
PathwayREACTOME_REPRESSION_OF_WNT_TARGET_GENES

TLE1 TLE2 TLE3 TLE4

4.61e-0810564MM15156
PathwayREACTOME_REPRESSION_OF_WNT_TARGET_GENES

TLE1 TLE2 TLE3 TLE4

2.17e-0714564M27402
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

TLE1 TLE2 TLE3 TLE4

3.13e-0626564MM14793
PathwayREACTOME_DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_COMPLEX

TLE1 TLE2 TLE3 TLE4

7.39e-0632564MM14975
PathwayBIOCARTA_FIBRINOLYSIS_PATHWAY

LPA PLG F2

1.27e-0512563MM1398
PathwayBIOCARTA_PLATELETAPP_PATHWAY

LPA PLG F2

2.10e-0514563MM1458
PathwayREACTOME_DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_COMPLEX

TLE1 TLE2 TLE3 TLE4

2.23e-0542564M27272
PathwayREACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

TLE1 TLE2 TLE3 TLE4

3.82e-0548564M611
PathwayREACTOME_SURFACTANT_METABOLISM

P2RY2 ADGRF5 DMBT1

9.94e-0523563MM15279
PathwayWP_BLOOD_CLOTTING_CASCADE

LPA PLG F2

9.94e-0523563MM15936
PathwayREACTOME_SIGNALING_BY_NOTCH1

TLE1 TLE2 TLE3 TLE4

2.09e-0474564M616
PathwayREACTOME_SURFACTANT_METABOLISM

P2RY2 ADGRF5 DMBT1

2.23e-0430563M27566
PathwayREACTOME_DEGRADATION_OF_BETA_CATENIN_BY_THE_DESTRUCTION_COMPLEX

TLE1 TLE2 TLE3 TLE4

2.69e-0479564MM14754
PathwayPID_SYNDECAN_4_PATHWAY

FN1 PLG F2

2.71e-0432563M165
PathwayWP_COVID19_THROMBOSIS_AND_ANTICOAGULATION

PLG F2

3.21e-047562M39868
PathwayREACTOME_DEGRADATION_OF_BETA_CATENIN_BY_THE_DESTRUCTION_COMPLEX

TLE1 TLE2 TLE3 TLE4

3.56e-0485564M27079
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

TLE1 TLE2 TLE3 TLE4

4.62e-0491564M27101
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

BMP1 FN1 LPA TNN LOXL4 PLG

5.35e-04258566MM14572
PathwayPID_ANGIOPOIETIN_RECEPTOR_PATHWAY

FN1 PLG F2

9.61e-0449563M92
PathwayBIOCARTA_FIBRINOLYSIS_PATHWAY

PLG F2

9.97e-0412562M2842
PathwayBIOCARTA_PLATELETAPP_PATHWAY

PLG F2

1.37e-0314562M6487
Pubmed

TLE expression correlates with mouse embryonic segmentation, neurogenesis, and epithelial determination.

TLE1 TLE2 TLE3 TLE4

2.73e-1148148645603
Pubmed

Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins.

TLE1 TLE2 TLE3 TLE4

1.36e-1058141303260
Pubmed

Molecular cloning and expression of mouse and human cDNA encoding AES and ESG proteins with strong similarity to Drosophila enhancer of split groucho protein.

TLE1 TLE2 TLE3 TLE4

1.36e-1058148365415
Pubmed

Protein characterization and targeted disruption of Grg, a mouse gene related to the groucho transcript of the Drosophila Enhancer of split complex.

TLE1 TLE2 TLE3 TLE4

4.08e-1068148573724
Pubmed

A Gro/TLE-NuRD corepressor complex facilitates Tbx20-dependent transcriptional repression.

TLE1 TLE2 TLE3 TLE4

9.50e-10781424024827
Pubmed

The Groucho-related gene family regulates the gonadotropin-releasing hormone gene through interaction with the homeodomain proteins MSX1 and OCT1.

TLE1 TLE2 TLE3 TLE4

1.90e-09881416002402
Pubmed

Nolz1 promotes striatal neurogenesis through the regulation of retinoic acid signaling.

TLE1 TLE2 TLE3 TLE4

1.90e-09881420735826
Pubmed

Spatial distribution of the full-length members of the Grg family during embryonic neurogenesis reveals a "Grg-mediated repression map" in the mouse telencephalon.

TLE1 TLE2 TLE3 TLE4

5.67e-091081430571765
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

LGALS9C BMP1 RELN FN1 LPA DMBT1 PLG F2

8.23e-0917581828071719
Pubmed

Coexpression of Cux-1 and Notch signaling pathway components during kidney development.

TLE1 TLE2 TLE3 TLE4

8.90e-091181415499562
Pubmed

Epithelial expression and chromosomal location of human TLE genes: implications for notch signaling and neoplasia.

TLE1 TLE2 TLE3

1.22e-0838138808280
Pubmed

Tle corepressors are differentially partitioned to instruct CD8+ T cell lineage choice and identity.

TLE1 TLE3 TLE4

1.22e-08381330045946
Pubmed

All Tcf HMG box transcription factors interact with Groucho-related co-repressors.

TLE1 TLE2 TLE3 TLE4

1.33e-081281411266540
Pubmed

Neurog2 simultaneously activates and represses alternative gene expression programs in the developing neocortex.

TLE1 TLE2 TLE3 TLE4

1.92e-081381422735158
Pubmed

Nkx2.2-repressor activity is sufficient to specify alpha-cells and a small number of beta-cells in the pancreatic islet.

TLE1 TLE2 TLE3 TLE4

2.68e-081481417202186
Pubmed

Developmental restriction of Mash-2 expression in trophoblast correlates with potential activation of the notch-2 pathway.

TLE1 TLE2 TLE3 TLE4

3.65e-08158149291577
Pubmed

Groucho-mediated transcriptional repression establishes progenitor cell pattern and neuronal fate in the ventral neural tube.

TLE1 TLE3 TLE4

4.86e-08481311290324
Pubmed

Ischemic stroke in PAR1 KO mice: Decreased brain plasmin and thrombin activity along with decreased infarct volume.

LPA PLG F2

4.86e-08481333720950
Pubmed

Groucho co-repressor proteins regulate β cell development and proliferation by repressing Foxa1 in the developing mouse pancreas.

TLE1 TLE2 TLE3 TLE4

8.15e-081881433658226
Pubmed

Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis.

TLE1 TLE2 TLE3 TLE4

8.15e-081881411731482
Pubmed

Grg3, a murine Groucho-related gene, is expressed in the developing nervous system and in mesenchyme-induced epithelial structures.

TLE1 TLE3 TLE4

1.21e-0758138989517
Pubmed

Transcriptional regulation of cortical neuron migration by POU domain factors.

RELN TLE1 TLE3 TLE4

1.29e-072081411859196
Pubmed

Transcripts of Grg4, a murine groucho-related gene, are detected in adjacent tissues to other murine neurogenic gene homologues during embryonic development.

TLE1 TLE3 TLE4

2.42e-0768138892234
Pubmed

Expression of Groucho/TLE proteins during pancreas development.

TLE1 TLE2 TLE3 TLE4

2.80e-072481418778483
Pubmed

A comparison of Notch, Hes and Grg expression during murine embryonic and post-natal development.

TLE1 TLE3 TLE4

6.76e-07881310512199
Pubmed

Constitutive scaffolding of multiple Wnt enhanceosome components by Legless/BCL9.

TLE1 TLE3 TLE4

6.76e-07881328296634
Pubmed

iCLIP predicts the dual splicing effects of TIA-RNA interactions.

TIA1 TIAL1

5.36e-06281221048981
Pubmed

Short-term inhibition of fibrinolytic system restores locomotor function after spinal cord injury in mice.

LPA PLG

5.36e-06281231690812
Pubmed

Blood-derived plasminogen drives brain inflammation and plaque deposition in a mouse model of Alzheimer's disease.

LPA PLG

5.36e-06281230254165
Pubmed

Plasminogen deficiency exacerbates skeletal muscle loss during mechanical unloading in developing mice.

LPA PLG

5.36e-06281238328826
Pubmed

Identification of chosen apoptotic (TIAR and TIA-1) markers expression in thyroid tissues from adolescents with immune and non-immune thyroid diseases.

TIA1 TIAL1

5.36e-06281220675271
Pubmed

Reduced transplant arteriosclerosis in plasminogen-deficient mice.

LPA PLG

5.36e-0628129819364
Pubmed

Persistent corneal haze after excimer laser photokeratectomy in plasminogen-deficient mice.

LPA PLG

5.36e-06281210634603
Pubmed

Thrombomodulin functions as a plasminogen receptor to modulate angiogenesis.

LPA PLG

5.36e-06281223943648
Pubmed

TIA-1 and TIAR activate splicing of alternative exons with weak 5' splice sites followed by a U-rich stretch on their own pre-mRNAs.

TIA1 TIAL1

5.36e-06281211514562
Pubmed

In vivo plasminogen deficiency reduces fat accumulation.

LPA PLG

5.36e-06281212083480
Pubmed

Polymorphonuclear leukocyte phagocytic function increases in plasminogen knockout mice.

LPA PLG

5.36e-06281218420257
Pubmed

Plasminogen deficiency causes severe thrombosis but is compatible with development and reproduction.

LPA PLG

5.36e-0628127705657
Pubmed

Nucleocytoplasmic coagulation: an injury-induced aggregation event that disulfide crosslinks proteins and facilitates their removal by plasmin.

LPA PLG

5.36e-06281223041318
Pubmed

Plasminogen alleles influence susceptibility to invasive aspergillosis.

LPA PLG

5.36e-06281218566672
Pubmed

A novel role for plasmin-mediated degradation of opsonizing antibody in the evasion of host immunity by virulent, but not attenuated, Francisella tularensis.

LPA PLG

5.36e-06281219752236
Pubmed

Two isoforms of the T-cell intracellular antigen 1 (TIA-1) splicing factor display distinct splicing regulation activities. Control of TIA-1 isoform ratio by TIA-1-related protein.

TIA1 TIAL1

5.36e-06281217488725
Pubmed

Plasminogen Tochigi: inactive plasmin resulting from replacement of alanine-600 by threonine in the active site.

LPA PLG

5.36e-0628126216475
Pubmed

The generation and characterization of mice expressing a plasmin-inactivating active site mutation.

LPA PLG

5.36e-06281220653841
Pubmed

Influence of plasminogen deficiency on the contribution of polymorphonuclear leucocytes to fibrin/ogenolysis: studies in plasminogen knock-out mice.

LPA PLG

5.36e-06281212428098
Pubmed

Streptococcus pneumoniae endopeptidase O (PepO) is a multifunctional plasminogen- and fibronectin-binding protein, facilitating evasion of innate immunity and invasion of host cells.

FN1 PLG

5.36e-06281223341464
Pubmed

Tissue-type plasminogen activator is a neuroprotectant in the mouse hippocampus.

LPA PLG

5.36e-06281220440070
Pubmed

Simultaneous thrombin and plasmin generation capacities in normal and abnormal states of coagulation and fibrinolysis in children and adults.

PLG F2

5.36e-06281221316746
Pubmed

Plasminogen deficiency causes reduced corticospinal axonal plasticity and functional recovery after stroke in mice.

LPA PLG

5.36e-06281224732409
Pubmed

A central role for plasminogen in the inflammatory response to biomaterials.

LPA PLG

5.36e-06281215456492
Pubmed

Gro/TLE enables embryonic stem cell differentiation by repressing pluripotent gene expression.

TLE3 TLE4

5.36e-06281225446531
Pubmed

Plasminogen promotes macrophage phagocytosis in mice.

LPA PLG

5.36e-06281224876560
Pubmed

Plasminogen is a joint-specific positive or negative determinant of arthritis pathogenesis in mice.

LPA PLG

5.36e-06281224574269
Pubmed

Spontaneous development of otitis media in plasminogen-deficient mice.

LPA PLG

5.36e-06281216956791
Pubmed

Staphylococcus aureus manganese transport protein C (MntC) is an extracellular matrix- and plasminogen-binding protein.

LPA PLG

5.36e-06281225409527
Pubmed

The mouse plasminogen locus maps to the recombination breakpoints of the tLub2 and TtOrl partial t haplotypes but is not at the tw73 locus.

LPA PLG

5.36e-0628121543918
Pubmed

Restoration of thrombolytic potential in plasminogen-deficient mice by bolus administration of plasminogen.

LPA PLG

5.36e-0628128704243
Pubmed

TLE3 and TLE4-coordinated colonic macrophage-CD4+ T cell crosstalk maintains intestinal immune homeostasis.

TLE3 TLE4

5.36e-06281236801171
Pubmed

Plasmin(ogen) promotes renal interstitial fibrosis by promoting epithelial-to-mesenchymal transition: role of plasmin-activated signals.

LPA PLG

5.36e-06281217267741
Pubmed

Plasmin promotes foam cell formation by increasing macrophage catabolism of aggregated low-density lipoprotein.

LPA PLG

5.36e-06281223702659
Pubmed

Apolipoprotein(a) inhibits the conversion of Glu-plasminogen to Lys-plasminogen on the surface of vascular endothelial and smooth muscle cells.

LPA PLG

5.36e-06281229990619
Pubmed

Reduction of experimental diabetic vascular leakage by delivery of angiostatin with a recombinant adeno-associated virus vector.

LPA PLG

5.36e-06281217293777
Pubmed

The stress granule component TIA-1 binds tick-borne encephalitis virus RNA and is recruited to perinuclear sites of viral replication to inhibit viral translation.

TIA1 TIAL1

5.36e-06281224696465
Pubmed

T-cell intracellular antigen (TIA)-proteins deficiency in murine embryonic fibroblasts alters cell cycle progression and induces autophagy.

TIA1 TIAL1

5.36e-06281224086455
Pubmed

Plasminogen plays a crucial role in bone repair.

LPA PLG

5.36e-06281223456978
Pubmed

Disruption of the plasminogen gene in mice abolishes wound healing after myocardial infarction.

LPA PLG

5.36e-06281210854210
Pubmed

Elements in the C terminus of apolipoprotein [a] responsible for the binding to the tenth type III module of human fibronectin.

FN1 LPA

5.36e-06281216150826
Pubmed

Gender affects skin wound healing in plasminogen deficient mice.

LPA PLG

5.36e-06281223527289
Pubmed

Dengue virus-induced autoantibodies bind to plasminogen and enhance its activation.

LPA PLG

5.36e-06281222079981
Pubmed

Class II ADP-ribosylation factors are required for efficient secretion of dengue viruses.

ARF4 ARF5

5.36e-06281222105072
Pubmed

Plasminogen deficiency differentially affects recruitment of inflammatory cell populations in mice.

LPA PLG

5.36e-0628129490683
Pubmed

Combinatorial expression patterns of individual TLE proteins during cell determination and differentiation suggest non-redundant functions for mammalian homologs of Drosophila Groucho.

TLE1 TLE4

5.36e-0628129572356
Pubmed

Kringle 5 of human plasminogen suppresses hepatocellular carcinoma growth both in grafted and xenografted mice by anti-angiogenic activity.

LPA PLG

5.36e-06281216481742
Pubmed

Apolipoprotein(a) inhibits the conversion of Glu-plasminogen to Lys-plasminogen: a novel mechanism for lipoprotein(a)-mediated inhibition of plasminogen activation.

LPA PLG

5.36e-06281218983515
Pubmed

Plasminogen Regulates Fracture Repair by Promoting the Functions of Periosteal Mesenchymal Progenitors.

LPA PLG

5.36e-06281234378815
Pubmed

Plasmin generation plays different roles in the formation and removal of arterial and venous thrombus in mice.

LPA PLG

5.36e-06281211848464
Pubmed

Effects of disruption of the plasminogen gene on thrombosis, growth, and health in mice.

LPA PLG

5.36e-0628127586361
Pubmed

Genome-wide profiling reveals a role for T-cell intracellular antigens TIA1 and TIAR in the control of translational specificity in HeLa cells.

TIA1 TIAL1

5.36e-06281224927121
Pubmed

Splicing of the large intron present in the nonstructural gene of minute virus of mice is governed by TIA-1/TIAR binding downstream of the nonconsensus donor.

TIA1 TIAL1

5.36e-06281219339348
Pubmed

Plasminogen/plasmin modulates bone metabolism by regulating the osteoblast and osteoclast function.

LPA PLG

5.36e-06281221239499
Pubmed

Plasminogen-independent initiation of the pro-urokinase activation cascade in vivo. Activation of pro-urokinase by glandular kallikrein (mGK-6) in plasminogen-deficient mice.

LPA PLG

5.36e-06281210642175
Pubmed

Plasminogen mRNA induction in the mouse brain after kainate excitation: codistribution with plasminogen activator inhibitor-2 (PAI-2) mRNA.

LPA PLG

5.36e-06281212225871
Pubmed

Fibrinogen deficiency reduces vascular accumulation of apolipoprotein(a) and development of atherosclerosis in apolipoprotein(a) transgenic mice.

LPA PLG

5.36e-0628129770530
Pubmed

Groucho/TLE family proteins and transcriptional repression.

TLE1 TLE3

5.36e-06281210831834
Pubmed

Structure, tissue distribution and genomic organization of the murine RRM-type RNA binding proteins TIA-1 and TIAR.

TIA1 TIAL1

5.36e-0628128871565
Pubmed

Identification of the sequence determinants mediating the nucleo-cytoplasmic shuttling of TIAR and TIA-1 RNA-binding proteins.

TIA1 TIAL1

5.36e-06281216278295
Pubmed

Plasminogen activation is required for the development of radiation-induced dermatitis.

LPA PLG

5.36e-06281230323258
Pubmed

Plasminogen deficiency suppresses pancreatic ductal adenocarcinoma disease progression.

LPA PLG

5.36e-06281237971174
Pubmed

The plasminogen activation system enhances brain and heart invasion in murine relapsing fever borreliosis.

LPA PLG

5.36e-0628129884337
Pubmed

Colonic Lesions, Cytokine Profiles, and Gut Microbiota in Plasminogen-Deficient Mice.

LPA PLG

5.36e-06281226473342
Pubmed

Nonfibrinolytic functions of plasminogen.

LPA PLG

5.36e-06281210816371
Pubmed

Plasminogen is a critical regulator of cutaneous wound healing.

LPA PLG

5.36e-06281226791370
Pubmed

Selection of mutant µplasmin for amyloid-β cleavage in vivo.

LPA PLG

5.36e-06281232694536
Pubmed

Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma.

LPA PLG

5.36e-0628127525077
Pubmed

Targeting TAO Kinases Using a New Inhibitor Compound Delays Mitosis and Induces Mitotic Cell Death in Centrosome Amplified Breast Cancer Cells.

TAOK2 TAOK1

5.36e-06281228830982
Pubmed

Individual RNA recognition motifs of TIA-1 and TIAR have different RNA binding specificities.

TIA1 TIAL1

5.36e-0628128576255
Pubmed

Contrasting roles of plasminogen deficiency in different rheumatoid arthritis models.

LPA PLG

5.36e-06281216052596
Pubmed

Functional corpora lutea are formed in matrix metalloproteinase inhibitor-treated plasminogen-deficient mice.

LPA PLG

5.36e-06281217122079
Pubmed

Fibronectin binds and enhances the activity of bone morphogenetic protein 1.

BMP1 FN1

5.36e-06281219617627
Pubmed

TIAR and TIA-1 mRNA-binding proteins co-aggregate under conditions of rapid oxygen decline and extreme hypoxia and suppress the HIF-1α pathway.

TIA1 TIAL1

5.36e-06281220980400
InteractionRIPPLY2 interactions

TLE1 TLE2 TLE3 TLE4

9.11e-0720774int:RIPPLY2
InteractionSIX6 interactions

TLE1 TLE3 TLE4

8.66e-0611773int:SIX6
InteractionHLX interactions

TLE1 TLE2 TLE3 TLE4

1.18e-0537774int:HLX
InteractionDAZAP1 interactions

PSAT1 FN1 TIA1 TIAL1 ARF4 ARF5

4.61e-05169776int:DAZAP1
InteractionCPB2 interactions

FN1 PLG F2

4.97e-0519773int:CPB2
InteractionRIPPLY1 interactions

TLE1 TLE2 TLE3 TLE4

5.79e-0555774int:RIPPLY1
InteractionSIX3 interactions

TLE1 TLE3 TLE4

5.83e-0520773int:SIX3
InteractionTBX20 interactions

TLE1 TLE3 TLE4

6.79e-0521773int:TBX20
InteractionMEP1A interactions

MEP1B FN1 PLG

1.02e-0424773int:MEP1A
CytobandEnsembl 112 genes in cytogenetic band chr6q26

LPA PLG

3.54e-0416802chr6q26
Cytoband4q28.1

FAT4 PRSS12

3.54e-04168024q28.1
Cytoband6q26

LPA PLG

4.51e-04188026q26
GeneFamilyWD repeat domain containing

WDR38 LRWD1 TLE1 TLE2 TLE3 TLE4 FBXW2 MLST8

1.56e-06262578362
GeneFamilyBeta-gamma crystallin domain containing

CRYBG2 CRYBG1

2.92e-0535721360
GeneFamilyMitogen-activated protein kinase kinase kinases|RAF family

TAOK2 TAOK1 MAP3K19

5.74e-0524573654
GeneFamilyBone morphogenetic proteins|Astacins

MEP1B BMP1

1.45e-046572894
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

ARF4 ARF5

4.28e-0331572357
CoexpressionHALLMARK_COAGULATION

BMP1 RGN FN1 PLG F2 ARF4

4.17e-06138806M5946
CoexpressionNABA_ECM_REGULATORS

MEP1B BMP1 PRSS12 LPA LOXL4 PLG F2

8.43e-06238807M3468
CoexpressionNABA_ECM_REGULATORS

MEP1B BMP1 PRSS12 LPA LOXL4 PLG F2

9.39e-06242807MM17062
CoexpressionHEBERT_MATRISOME_TNBC_LIVER_METASTASIS

FN1 PLG F2

9.73e-0614803M48002
CoexpressionHUANG_FOXA2_TARGETS_UP

PSAT1 FN1 TLE4 LHFPL6

1.30e-0547804M15326
CoexpressionDESCARTES_ORGANOGENESIS_HEPATOCYTES

RGN PSAT1 FN1 LPA ZNF395 PLG F2 MMD2 ALDH7A1

3.68e-05535809MM3635
CoexpressionNABA_MATRISOME

MEP1B LGALS9C BMP1 RELN FN1 PRSS12 LPA TNN LOXL4 DMBT1 PLG F2

5.30e-0510088012MM17056
CoexpressionNABA_MATRISOME

MEP1B LGALS9C BMP1 RELN FN1 PRSS12 LPA TNN LOXL4 DMBT1 PLG F2

6.28e-0510268012M5889
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_top-relative-expression-ranked_1000

MEP1B RGN PSAT1 TIA1 TIAL1 GPATCH2 CRYBG1 UBR3 FBXW2 TAOK1 KLHDC10 ARF4

2.41e-057747812gudmap_developingKidney_e15.5_cortic collect duct_1000
ToppCellRA-07._Pericyte|World / Chamber and Cluster_Paper

FN1 TLE1 TLE2 APBB2 LHFPL6

1.93e-051828052075efeae633550fb2eb026d0dfd741c8252482e
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 RELN LOXHD1 PKHD1L1 DNAH11

2.03e-051848052cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 RELN LOXHD1 PKHD1L1 DNAH11

2.03e-05184805ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 RELN LOXHD1 PKHD1L1 DNAH11

2.03e-051848052b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FN1 TLE1 APBB2 LHFPL6 ADGRF5

2.43e-051918057b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FN1 TLE1 APBB2 LHFPL6 ADGRF5

2.43e-05191805cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCell367C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SLC6A6 BMP1 FN1 TNN ARF5

2.89e-05198805c55608633f66e3d434c5d81324efb07c5120d2c2
ToppCell367C-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SLC6A6 BMP1 FN1 TNN ARF5

2.89e-051988053e5459038fc6ed95f529eb4d1dc5113e16c19012
ToppCell(5)_Fibroblasts-(5)_Fibroblast-B_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

SLC6A6 BMP1 FN1 TNN APBB2

2.89e-05198805196257c4420ac801ed9fbb444f11718adb7560ae
ToppCellHematolymphoid-Endothelial-NOSTRIN|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SLC7A1 TLE1 APBB2 LHFPL6 ADGRF5

3.03e-05200805032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCellHematolymphoid-Endothelial-NOSTRIN---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SLC7A1 TLE1 APBB2 LHFPL6 ADGRF5

3.03e-0520080568fce28690246895fd33354b30960ebcc31aa4cc
ToppCellHematolymphoid-Endothelial-NOSTRIN-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SLC7A1 TLE1 APBB2 LHFPL6 ADGRF5

3.03e-05200805376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCellHematolymphoid-Endothelial-NOSTRIN--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SLC7A1 TLE1 APBB2 LHFPL6 ADGRF5

3.03e-052008057fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCellHematolymphoid-Endothelial-NOSTRIN----L2-6|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SLC7A1 TLE1 APBB2 LHFPL6 ADGRF5

3.03e-05200805878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCellHematolymphoid-Endothelial|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SLC7A1 TLE1 APBB2 LHFPL6 ADGRF5

3.03e-052008057136936d05ab344a560cf159684c881063b5430d
ToppCellControl-B_naive-9|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

CD300LF ZNF395 PLG TRMT61A

6.51e-0512080462d3a731d36802c9da8674a042a8604cdb86263a
ToppCelldroplet-Liver-Hepatocytes-24m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF395 PLG F2 ALDH7A1

1.35e-04145804f142b86d4da5b71c189da46cbc4beebdc387ffee
ToppCelldroplet-Liver-nan-3m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGN FN1 PLG F2

1.58e-04151804cc9632b58522e2ba3ad36a0b8d37c7c9c8b636c4
ToppCelldroplet-Liver-nan-3m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGN FN1 PLG F2

1.58e-041518047758cfbe8dca849c90bd6e8bc63310e53beeb8fd
ToppCelldroplet-Liver-nan-3m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGN FN1 PLG F2

1.58e-04151804b4a0546c1573b4b2290890307f2a5daf3a7cbb37
ToppCellLPS-IL1RA-Epithelial_airway-Ciliated_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WDR38 NME9 MAP3K19 DNAH11

1.58e-0415180481cf939ed4df9574fbfff265e109cb9f947d7e6e
ToppCellLPS-IL1RA-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WDR38 NME9 MAP3K19 DNAH11

1.58e-041518049cbcbbc22965a9f0be8364e733d205dd64f2a533
ToppCelldroplet-Liver-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGN FN1 PLG F2

1.62e-041528041febeeb7376e34b9f86c81b2cb1314ee12408864
ToppCelldroplet-Liver-nan-3m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGN FN1 PLG F2

1.62e-04152804faa92f7c5a6db9f1eb7d8ec930ba7c8ed9fd1bf1
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WDR38 NME9 MAP3K19 DNAH11

1.75e-041558045f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WDR38 NME9 MAP3K19 DNAH11

1.75e-041558040944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A6 FN1 P2RY2 ADGRF5

1.79e-041568040695ac0f02d059ecf813d61d3c9d4c76d1d85834
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A6 FN1 P2RY2 ADGRF5

1.79e-041568041c2920f4356789a9c11d5ea1eaafb18a50b19ed7
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A6 FN1 P2RY2 ADGRF5

1.79e-04156804a45fbe02cd03bd4a097f21368bc1179779ba0db8
ToppCelldroplet-Liver-nan-3m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGN FN1 PLG F2

1.84e-04157804b72c6a1ed17bfc32d9dec193d934ea82e80b6bd5
ToppCellfacs-Liver|facs / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGN FN1 PLG F2

1.88e-04158804ea7db6bd9742153ceb6e444892a6d1df9c7fcc96
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEP1B WDR38 NME9 DNAH11

1.93e-0415980400a157d033627d0e65c3fbd38d652c4cf56b47f6
ToppCelldroplet-Liver-Hepatocytes-18m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGN FN1 PLG F2

2.02e-04161804274838cebdc7af1db32d309dfe42ef7ccd3c190b
ToppCelldroplet-Marrow-BM-30m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP1 FN1 ADGRE4P PRKCE

2.07e-0416280475df7ff779a3b9159ba97d852da1f8df650b9ce5
ToppCelldroplet-Liver-Hepatocytes-18m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGN FN1 PLG F2

2.12e-0416380403d9fa615d9d02ef98e20f28a10aaa6894dd4960
ToppCelldroplet-Liver-Hepatocytes-18m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGN FN1 PLG F2

2.12e-041638041c4de36cf8cdaabb981cda5c7ce7e5ae7b4280e3
ToppCelldroplet-Liver-Hepatocytes-18m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGN FN1 PLG F2

2.12e-041638047e82c1b7849eca895732df2da74ac6430bd9ba7a
ToppCellPSB-critical-LOC-Lymphoid-PC|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SLC6A11 PSAT1 IL1RL2 PKHD1L1

2.17e-041648043e672124dea2497c5bdf8a315c8cfacfab5780dc
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_2|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

WDR38 NME9 INPP5J DNAH11

2.22e-04165804731147b4337fd0de4383dc8170b4f9ccd98caec6
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

APBB2 LHFPL6 ADGRF5 DNAH11

2.22e-04165804369d77a80d6401e85ea3121ab5a252f67d5f157e
ToppCellCiliated_cells-B-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

BMP1 WDR38 PRSS12 DNAH11

2.27e-041668044b1056aad8a99827835242b8ab0c7f2bb84471f1
ToppCell15-Distal-Epithelial-Multiciliated_precursor|Distal / Age, Tissue, Lineage and Cell class

WDR38 NME9 MAP3K19 DNAH11

2.32e-04167804442ea71a581ed5a547a214132b9f1b0243fd0895
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSAT1 FN1 PLG F2

2.38e-04168804b98af4043dfa5dfa4413e482879fad88de484675
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSAT1 FN1 PLG F2

2.38e-04168804073b53d4cee6bc8c5c6fce51cf6cd9c316478f69
ToppCelldroplet-Liver-HEPATOCYTES|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSAT1 FN1 PLG F2

2.43e-04169804f195467438c589f87224bde7da720dea072d110c
ToppCelldroplet-Liver-HEPATOCYTES-1m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSAT1 FN1 PLG F2

2.43e-041698047785cab967a33560830c394c918d6ce625103858
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-6_VIP_PENK|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT4 RELN TLE2 DNAH11

2.43e-04169804eb3b8e473192c4b8688f2f8da400116dd6fe193d
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 TLE2 LOXL4 TRMT61A

2.49e-0417080445de83a2231208b8e1f21061d0b91644b4a3ba93
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PSAT1 LRWD1 FN1 TSSK4

2.60e-04172804ebeda7ef181cac0109be750a98e7589c615d2724
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN FN1 ADGRF5 PKHD1L1

2.60e-04172804c056d44e2e130ceccadfcdceb192a7f095d779c8
ToppCellAT1_cells-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

SLC7A1 PSAT1 CRYBG2 APBB2

2.66e-04173804b29816427428c7053017477f59b828bf1357f3b2
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PSAT1 RELN PRSS12 MMD2

2.66e-04173804789ab8b2709f4b8728e3733bc72744e9d92ea5ea
ToppCell390C-Lymphocytic-NK_cells-NK_cell_A2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CRYBG2 TIA1 KIAA0513 USP32

2.78e-04175804334fad1a147de6c007cec5089c02c35cf3220f1b
ToppCell390C-Lymphocytic-NK_cells-NK_cell_A2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

CRYBG2 TIA1 KIAA0513 USP32

2.78e-04175804da191dfb8a7f976a632a3a0b923942ab54f5c8c1
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LPA LHFPL6 ADGRF5 DNAH11

2.84e-041768048b5c2fb7e5e551df658b1d5fc7f607a27bab00d5
ToppCellE12.5-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RELN FN1 PRSS12 LHFPL6

2.90e-041778045cdf413f82376a95467322b16d10b0d1e7557e2d
ToppCellfacs-Thymus-Epithelium-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD300LF TLE1 PRKCE ARF4

2.90e-04177804c2b8a3a149d70f77612759dea34df9e43953c566
ToppCellfacs-Thymus-Epithelium-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD300LF TLE1 PRKCE ARF4

2.90e-04177804384f841aa7b2d05815af7885e481f5affc55d897
ToppCellfacs-Thymus-Epithelium-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD300LF TLE1 PRKCE ARF4

2.90e-041778040e9e44119653abfd270e602e5e477a15e774638f
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 APBB2 LHFPL6 ADGRF5

2.90e-041778048ef41ee5d63737b810ad7371b0437625e7e1badf
ToppCellCiliated_cells-A-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

WDR38 NME9 MAP3K19 DNAH11

2.96e-04178804255473ee6df8a13079fb3bb61038162a40cb4c2c
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A6 SLC7A1 FN1 ADGRF5

3.09e-041808042405aa5699a8d8cf4c6b3dca07510e774728ac50
ToppCellIIH-CD8-CD4_Treg|IIH / Condition, Cell_class and T cell subcluster

TAOK2 SLC7A1 LRWD1 CEP152

3.09e-04180804d1a8b25115c80e5a5bd0b8244167a98250ab9778
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A6 SLC7A1 FN1 ADGRF5

3.09e-041808049c47852c0a723e2f5cd6898afff4c31a0da06905
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A6 SLC7A1 FN1 ADGRF5

3.09e-04180804499d5fe71e0dc20cffdf85e3b3f14eb4e83e3a3d
ToppCellIIH-plasma|IIH / Condition, Cell_class and T cell subcluster

RGN RELN LHFPL6 TSSK4

3.16e-0418180413d1f31bcbac21aea91de74f51eed549ec61003e
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 APBB2 LHFPL6 ADGRF5

3.16e-041818044df7972f88117108698efd06b124b232f8588981
ToppCellIIH-plasma-|IIH / Condition, Cell_class and T cell subcluster

RGN RELN LHFPL6 TSSK4

3.16e-04181804140ac43dc6b89396872f908c14c89278f6d982b2
ToppCell10x5'-bone_marrow-Myeloid_Mac-Macrophage|bone_marrow / Manually curated celltypes from each tissue

PSAT1 FN1 CLIP2 TLE3

3.16e-04181804d2aa5b53162fb5c4cbbedbd2cb4b2b614e8c4afa
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L3_VIP_CBLN1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC6A11 FAT4 RELN LHFPL6

3.16e-041818047846c7b33d1b89364c5a704edaa86520db731c89
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 APBB2 LHFPL6 ADGRF5

3.16e-04181804cbb530566893281289026bfd93adf721decd4ca3
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A6 SLC7A1 FN1 ADGRF5

3.22e-04182804e6a734fb29105093d4cbfc3d0619a825b66da034
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

WDR38 SLC6A11 FAT4 RELN

3.22e-04182804d3a037268f026eb2f84428b1821022503cef7756
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A6 SLC7A1 FN1 ADGRF5

3.22e-04182804ccc313ecc0bfd8e2c6bb83a565b427b2310485ec
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A6 SLC7A1 FN1 ADGRF5

3.22e-04182804b9f758961fb4a586ae86fa0b25edb8ce4616d644
ToppCellLA-07._Pericyte|World / Chamber and Cluster_Paper

TLE1 APBB2 LHFPL6 ADGRF5

3.29e-04183804e3835db4795362b0442d5893baf2a78efcc20428
ToppCellfacs-Skin-Telogen-3m-Epithelial-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSAT1 CRYBG2 KIAA0513 IL1RL2

3.29e-0418380426b18d1cc5d98f185176e100bafb9bc9081c66f7
ToppCellControl-CD8+_T_activated|Control / Disease group and Cell class

KIAA0513 PRKCE MLST8 RAI1

3.36e-04184804b86cc48b744b3206880ec1373fe6068e14bf9680
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A6 SLC7A1 FN1 ADGRF5

3.43e-041858047f46ea82a663181957f88e4e83114aef8a78820c
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A6 SLC7A1 FN1 ADGRF5

3.43e-04185804956fb0043c0c3e4e5c4d6f58ff95faf6209c380e
ToppCell15-Airway-Epithelial-Multiciliated_cell|Airway / Age, Tissue, Lineage and Cell class

WDR38 NME9 MAP3K19 DNAH11

3.43e-041858040998b6bf44287eebbf39249fff23fc3689e44c4e
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN ADGRF5 PKHD1L1 RNF215

3.43e-0418580459acaf025353405948dc34ccccf37ec5c08ea903
ToppCellMesenchymal_cells-Osteo-CAR|World / Lineage and Cell class

FAT4 TLE2 LHFPL6 MMD2

3.43e-0418580416f1588893d09c864e0cb4f837a1b972a1a57baa
ToppCellCiliated_cells-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

WDR38 NME9 MAP3K19 DNAH11

3.50e-04186804f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC6A11 RELN LHFPL6 PKHD1L1

3.50e-0418680440070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A6 SLC7A1 FN1 ADGRF5

3.50e-04186804ba6ba75218efc26371cea24ddbb0e9b3e3f421ac
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A6 SLC7A1 FN1 ADGRF5

3.50e-04186804a58c9d1567da0961e0e295a156773d2252ee5a1a
ToppCell(4)_Lymph_vessel|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

RELN LHFPL6 ADGRF5 PKHD1L1

3.50e-041868046b3afc2ae870ff73e30a60ce84fcee0eb365d809
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A6 SLC7A1 FN1 ADGRF5

3.50e-0418680465e25a9dcef5fc71510aaf170e220deef5b2feb2
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A6 SLC7A1 FN1 ADGRF5

3.50e-04186804e4f1259725160719e5fd13d76e5a707efed70013
ToppCellIPF-Epithelial-ATII|Epithelial / Disease state, Lineage and Cell class

BMP1 LHFPL6 ADGRF5 DMBT1

3.64e-041888045f5fad2773e421760e67dbace23fd1f847a2e1e0
ToppCellEndothelial-endothelial_cell_of_lymph_vessel|World / Lineage, Cell type, age group and donor

SLC7A1 RELN TLE1 PKHD1L1

3.64e-0418880480910dcbb51990f2baed240f319456c0d3fa2065
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

SLC7A1 PSAT1 ADGRF5 DMBT1

3.64e-04188804ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLE2 TNN MMD2 INPP5J

3.64e-04188804315ce1736e3a84a63a8d5dfa70d411b501cb2532
ToppCellASK428-Endothelial-Lymphatic|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

FAT4 RELN LHFPL6 PKHD1L1

3.64e-04188804c371bc340966cfe9205cbf4b62c6452f49f2559f
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

WDR38 PRSS12 MAP3K19 DNAH11

3.72e-04189804a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellfacs-Thymus-Epithelium-3m-Mesenchymal|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP1 FN1 P2RY2 LHFPL6

3.72e-041898041db5dd1ef2a65251af2d5696622d1dd9c4ae2b55
ToppCellfacs-Thymus-Epithelium-3m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP1 FN1 P2RY2 LHFPL6

3.72e-04189804bfb1c183a8a2752a2368b74150e66181c6a9da48
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

FN1 TLE1 ADGRF5 PKHD1L1

3.72e-04189804c81787a8c662db5d7814c583dd64562857629e81
ToppCellfacs-Thymus-Epithelium-3m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP1 FN1 P2RY2 LHFPL6

3.72e-0418980414833feea8f80744a06ece73f813eaeff8c4dd61
ComputationalGenes in the cancer module 371.

BMP1 ARF4 ARF5

1.45e-0426433MODULE_371
DrugZuclopenthixol hydrochloride [633-59-0]; Up 200; 9.2uM; HL60; HT_HG-U133A

TAOK2 CDK20 CRYBG2 CLIP2 BTNL3 APBB2 PRKCE INPP5J

3.35e-071997682936_UP
Drugbz-Ar

FN1 PLG F2

1.24e-067763CID000137302
DrugCefadroxil [50370-12-2]; Down 200; 11uM; PC3; HT_HG-U133A

TAOK2 BMP1 SLC7A1 PRSS12 TLE1 APBB2 ALDH7A1

4.45e-061987674080_DN
DrugTolbutamide [64-77-7]; Up 200; 14.8uM; HL60; HT_HG-U133A

MEP1B SLC7A1 FN1 CLIP2 TLE3 APBB2 LHFPL6

4.60e-061997672359_UP
DrugPAMBA

LPA PLG F2

9.98e-0613763CID000065526
DrugRgdf peptide

FN1 PLG F2

1.27e-0514763CID003080994
DrugAminocaproic Acid

LPA PLG

3.29e-053762DB00513
DrugAC1MJ08J

PLG F2

3.29e-053762CID003083201
Drug5-APA

PLG F2

3.29e-053762CID000130129
DrugMDL 27,032

FN1 PRKCE ALDH7A1

4.55e-0521763CID000163812
DrugIopanoic acid [96-83-3]; Up 200; 7uM; HL60; HT_HG-U133A

TAOK2 CDK20 SLC7A1 KIAA0513 TLE3 ADGRF5

4.72e-051947662965_UP
DrugMolsidomine [25717-80-0]; Up 200; 16.6uM; MCF7; HT_HG-U133A

FAT4 RELN TLE1 TNN DMBT1 INPP5J

5.00e-051967662862_UP
DrugNortriptyline hydrochloride [894-71-3]; Down 200; 13.4uM; MCF7; HT_HG-U133A

BMP1 SLC7A1 TIA1 TLE4 APBB2 TRMT61A

5.00e-051967666003_DN
DrugIsoxsuprine hydrochloride [579-56-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A

TAOK2 CDK20 FN1 TLE1 APBB2 CEP152

5.14e-051977661485_UP
Drugcobalt(II) chloride hexahydrate; Down 200; 100uM; MCF7; HG-U133A

TAOK2 MEP1B BMP1 TLE2 TNN PRKCE

5.29e-05198766383_DN
DrugLymecycline [992-21-2]; Up 200; 6.6uM; MCF7; HT_HG-U133A

SLC6A6 BMP1 CRYBG2 FN1 APBB2 PRKCE

5.44e-051997665994_UP
DrugRibavirin [36791-04-5]; Up 200; 16.4uM; MCF7; HT_HG-U133A

SLC6A6 BMP1 SLC7A1 CLIP2 TLE4 NEK9

5.44e-051997666521_UP
DrugKanamycin A sulfate [25389-94-0]; Down 200; 6.8uM; PC3; HT_HG-U133A

TAOK2 BMP1 FAT4 KIAA0513 APBB2 ALDH7A1

5.59e-052007664625_DN
DrugRdv peptide

FN1 F2

6.57e-054762CID000196843
Drugcyclopropylurea

F2 ALDH7A1

6.57e-054762CID000272626
Drugcyclooctylurea

F2 ALDH7A1

6.57e-054762CID000294524
DrugAC1L3VFE

RGN TLE2 TLE3 ALDH7A1

6.65e-0565764CID000122880
DrugGestodene

FN1 PLG F2

8.79e-0526763ctd:C033273
DrugAC1Q5XME

PLG F2

1.09e-045762CID000189740
Drugmethyl urethane

TAOK2 RELN

1.09e-045762CID000007752
DrugT at 10

PLG F2

1.09e-045762CID000480141
DrugCerebro

CDK20 RGN LPA

1.10e-0428763CID000005354
Drugiprindole

LOXL4 MLST8 F2

1.10e-0428763CID000021722
Drug8-CPT-cAMP

CDK20 P2RY2 LPA PRKCE ALDH7A1

1.22e-04144765CID000001903
DrugH743

PLG F2

1.64e-046762CID005488509
DrugFqvvcg-nh2

PLG F2

1.64e-046762CID003083094
DrugF 29

FN1 PLG

1.64e-046762CID006419426
DrugSuramin

P2RY2 F2

1.64e-046762DB04786
DrugPKSI-1007

PLG F2

1.64e-046762CID000130064
DrugTAPNP

PLG F2

1.64e-046762CID000133888
DrugGly-pro-arg

FN1 PLG F2

1.65e-0432763CID000170776
Drugh x mg

LPA PRKCE PLG

1.99e-0434763CID000001380
DrugDuP-714

PLG MLST8 F2

2.17e-0435763CID000122296
DrugFactor Xiiib

LPA PLG F2

2.17e-0435763CID000126166
DrugT-NK

SLC7A1 PLG F2

2.17e-0435763CID000446515
Drugsatigrel

F2 ALDH7A1

2.28e-047762CID000065913
DrugAC1N17P1

PLG F2

2.28e-047762CID003976779
Drugaureothricin

TAOK2 TAOK1

2.28e-047762CID000068460
DrugGly-his-arg

PLG F2

2.28e-047762CID000133872
DrugI5B1

LPA PRKCE PLG

2.56e-0437763CID005487705
DrugCephaeline dihydrochloride heptahydrate [6487-30-5]; Down 200; 6uM; HL60; HT_HG-U133A

SLC7A1 FN1 CEP152 ZNF395 TRMT61A

2.71e-041717652429_DN
Drug5'-N-ethylcarboxamidoadenosine

P2RY2 PRKCE PLG F2 ALDH7A1

2.93e-04174765CID000104795
DrugContraceptives, Oral, Combined

PLG F2

3.04e-048762ctd:D003277
DrugGGACK

PLG F2

3.04e-048762CID003080903
DrugAC1NDMP4

PLG F2

3.04e-048762CID004628293
DrugF 20

FN1 PLG

3.04e-048762CID009547917
Drugnitrefazole

LPA ALDH7A1

3.04e-048762CID000071900
DrugBio-Phe-CH2Cl

PLG F2

3.04e-048762CID000083924
DrugBio-Arg-CH2Cl

PLG F2

3.04e-048762CID000083923
DrugDesaa-fibrin

PLG F2

3.04e-048762CID000127263
DrugGRGDTP

FN1 LPA

3.04e-048762CID004644096
DrugS 2251

LPA PLG F2

3.23e-0440763CID000124997
Drugdoxepin

SLC6A11 TRIM32 LOXL4

3.23e-0440763CID000003158
Drugindo-1

P2RY2 PRKCE F2 ALDH7A1

3.39e-0499764CID000105060
Drugsarcosine

BMP1 SLC7A1 LPA ARF5

3.53e-04100764CID000001088
DrugGrgesp

FN1 LPA F2

3.74e-0442763CID000492974
Drugpioglitazone HCl; Up 200; 10uM; PC3; HT_HG-U133A

SLC7A1 FN1 BTNL3 APBB2 DMBT1

3.89e-041857657528_UP
Drug4Amf

PLG F2

3.90e-049762CID000150955
Drugpyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid

FN1 P2RY2

3.90e-049762ctd:C077792
DrugFK-401

PLG F2

3.90e-049762CID000135041
DrugtlmE

PLG F2

3.90e-049762CID000188322
Drugdansyl-L-arginine

PLG F2

3.90e-049762CID000119895
DrugThiram

RGN ABI1 TNN LHFPL6 PRKCE GPSM1 TRMT61A ARF5

3.99e-04533768ctd:D013893
DrugGly-pro-arg-pro

FN1 PLG F2

4.01e-0443763CID000123681
DrugPyoverdin

FN1 LPA PLG

4.01e-0443763CID005289234
DrugAdenosine 5'-monophosphate monohydrate [18422-05-4]; Down 200; 11uM; HL60; HG-U133A

SLC7A1 FN1 P2RY2 MLST8 KLHDC10

4.18e-041887651622_DN
Drugdl-Lysine

TAOK2 SLC7A1 FN1 PLG F2 ALDH7A1

4.20e-04290766CID000000866
DrugClioquinol [130-26-7]; Up 200; 13uM; HL60; HT_HG-U133A

RELN FN1 KIAA0513 CLIP2 INPP5J

4.29e-041897653084_UP
DrugBacitracin

BMP1 RGN FN1

4.29e-0444763ctd:D001414
Drugmaprotiline

SLC6A11 LOXL4 MLST8

4.29e-0444763CID000004011
DrugAC1OAGFB

FN1 PRKCE ZNF395 MLST8 F2 INPP5J ARF4 ARF5

4.30e-04539768CID006857345
DrugNaftopidil dihydrochloride [57149-08-3]; Up 200; 8.6uM; HL60; HT_HG-U133A

CRYBG2 FN1 BTNL3 TNN APBB2

4.39e-041907652911_UP
DrugDrofenine hydrochloride [548-66-3]; Up 200; 11.4uM; MCF7; HT_HG-U133A

SLC6A6 BMP1 PRKCE NEK9 INPP5J

4.50e-041917656776_UP
DrugMelatonin [73-31-4]; Down 200; 17.2uM; MCF7; HT_HG-U133A

TAOK2 SLC6A6 TLE2 TRMT2B NEK9

4.72e-041937653293_DN
DrugProcaine hydrochloride [51-05-8]; Down 200; 14.6uM; MCF7; HT_HG-U133A

TAOK2 SLC7A1 PRKCE NEK9 INPP5J

4.72e-041937655430_DN
DrugColchicine [64-86-8]; Up 200; 10uM; MCF7; HT_HG-U133A

BMP1 KIAA0513 DMBT1 PLG ALDH7A1

4.83e-041947653213_UP
DrugMethoxy-6-harmalan [3589-73-9]; Up 200; 18.6uM; MCF7; HT_HG-U133A

SLC6A6 FN1 TIAL1 PRKCE PLG

4.83e-041947652893_UP
DrugBeta-Escin [11072-93-8]; Down 200; 3.2uM; PC3; HT_HG-U133A

FAT4 FN1 KIAA0513 CRYBG1 NEK9

4.83e-041947653807_DN
DrugHaloperidol [52-86-8]; Up 200; 10.6uM; PC3; HT_HG-U133A

MEP1B SLC6A6 PRKCE ADGRF5 NEK9

4.83e-041947654678_UP
DrugGraveoline [485-61-0]; Up 200; 14.4uM; PC3; HT_HG-U133A

TAOK2 CDK20 BMP1 TNN CEP152

4.83e-041947653716_UP
DrugSR 26831

PLG F2

4.86e-0410762CID000132270
Drugamoxapine

SLC6A11 TRIM32 LOXL4

4.89e-0446763CID000002170
Drugionomycin calcium salt; Up 200; 2uM; MCF7; HT_HG-U133A_EA

CDK20 BMP1 TLE1 APBB2 INPP5J

4.94e-04195765871_UP
DrugDipyridamole [58-32-2]; Up 200; 8uM; MCF7; HT_HG-U133A

TAOK2 CDK20 FN1 ADGRF5 DMBT1

4.94e-041957651517_UP
DrugHydrastinine hydrochloride [4884-68-8]; Down 200; 16.4uM; MCF7; HT_HG-U133A

CDK20 SLC7A1 APBB2 INPP5J ALDH7A1

4.94e-041957652283_DN
DrugBetahistine mesylate [54856-23-4]; Up 200; 17.2uM; MCF7; HT_HG-U133A

SLC6A6 SLC7A1 FN1 TLE2 APBB2

4.94e-041957652833_UP
Drugtrichostatin A; Up 200; 0.1uM; HL60; HG-U133A

BMP1 FN1 TLE1 PRKCE NEK9

4.94e-04195765364_UP
DrugDihydroergocristine mesylate [24730-10-7]; Up 200; 5.6uM; MCF7; HT_HG-U133A

TAOK2 BMP1 FN1 APBB2 INPP5J

4.94e-041957652895_UP
DrugPhenelzine sulfate [156-51-4]; Down 200; 17uM; MCF7; HT_HG-U133A

TAOK2 CDK20 SLC6A6 BMP1 TLE1

4.94e-041957654360_DN
DrugGuanfacine hydrochloride [29110-48-3]; Up 200; 14.2uM; MCF7; HT_HG-U133A

CDK20 FAT4 LPA TLE4 CEP152

4.94e-041957655256_UP
Drugnickel chloride

CDK20 MEP1B RGN PSAT1 FN1 TIA1 TIAL1 P2RY2 TLE3 APBB2 FBXW2 PLG

5.02e-0411787612ctd:C022838
DrugPiribedil hydrochloride [78213-63-5]; Up 200; 12uM; HL60; HT_HG-U133A

SLC6A6 FN1 CLIP2 TLE3 PRKCE

5.06e-041967652951_UP
DrugPramoxine hydrochloride [637-58-1]; Down 200; 12.2uM; HL60; HT_HG-U133A

BMP1 SLC7A1 PRSS12 PRKCE NEK9

5.06e-041967652198_DN
DrugTorsemide [56211-40-6]; Up 200; 11.4uM; MCF7; HT_HG-U133A

SLC7A1 FAT4 TIAL1 APBB2 ADGRF5

5.06e-041967653517_UP
DrugEtilefrine hydrochloride [534-87-2]; Down 200; 18.4uM; MCF7; HT_HG-U133A

FN1 APBB2 PRKCE INPP5J ALDH7A1

5.06e-041967654415_DN
Diseasecalcium oxalate nephrolithiasis (biomarker_via_orthology)

FN1 F2

1.91e-053752DOID:0080652 (biomarker_via_orthology)
DiseaseDeep Vein Thrombosis

LPA PLG F2

2.03e-0521753C0149871
DiseaseVenous Thrombosis

LPA PLG F2

2.03e-0521753C0042487
Diseasecysteine-rich secretory protein LCCL domain-containing 2 measurement

P2RY2 USP32

3.81e-054752EFO_0801512
Diseasechronic kidney disease, APOL1 risk genotype carrier status

LPA PLG

6.34e-055752EFO_0003884, EFO_0009324
Diseaseplasma plasminogen measurement

LPA PLG

6.34e-055752EFO_0006309
Diseaseangiostatin measurement

LPA PLG

9.50e-056752EFO_0008024
Diseaselipoprotein A measurement, apolipoprotein A 1 measurement

LPA PLG

1.33e-047752EFO_0004614, EFO_0006925
Diseasefamilial Mediterranean fever (is_marker_for)

LPA F2

2.27e-049752DOID:2987 (is_marker_for)
Diseasemyocardial infarction

BMP1 FN1 LPA DMBT1 PLG GPSM1

2.70e-04350756EFO_0000612
Diseaseniacinamide measurement

ZNF395 EXOC2

4.14e-0412752EFO_0010511
DiseaseThromboembolism

LPA F2

4.14e-0412752C0040038
Diseasemonocyte count

CRYBG2 FN1 CD300LF P2RY2 LPA PRKCE ADGRF5 PLG F2 RAI1 MAP3K19

4.86e-0413207511EFO_0005091
DiseaseAlcohol abuse

CDK20 FN1 F2

6.72e-0467753C0085762
Diseasecentral nervous system disease (implicated_via_orthology)

TAOK2 TAOK1

7.48e-0416752DOID:331 (implicated_via_orthology)
Diseasecoronary artery disease

BMP1 FAT4 FN1 CD300LF LPA PRKCE PLG GPSM1 NEK9 RAI1

8.62e-0411947510EFO_0001645
Diseaseglomerulonephritis (is_marker_for)

FN1 F2

1.06e-0319752DOID:2921 (is_marker_for)
Diseasealpha-tocopherol measurement

PRKCE RNF215

1.18e-0320752EFO_0007898
DiseaseAgents acting on the renin-angiotensin system use measurement

SLC7A1 STIM2 LPA PRKCE NME9

1.65e-03335755EFO_0009931
DiseaseCoronary heart disease

LPA DNAH11

1.70e-0324752C0010068
Diseaselow density lipoprotein cholesterol measurement, alcohol consumption measurement

LPA PLG DNAH11

2.08e-0399753EFO_0004611, EFO_0007878
Diseaselow density lipoprotein cholesterol measurement, alcohol drinking

LPA PLG DNAH11

2.26e-03102753EFO_0004329, EFO_0004611
DiseaseWeight Gain

STIM2 APBB2 DNAH11

2.26e-03102753C0043094
Diseasehypertrophic cardiomyopathy (implicated_via_orthology)

STIM2 COX6B1

2.48e-0329752DOID:11984 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
DVGQNVGWYVGVCRD

BTNL3

346

Q6UXE8
YDQGVDLWSVGCIMG

CDK20

181

Q8IZL9
YAGEKCGNVWEENRS

CEP152

96

O94986
TQVGWHGETYCLVGG

DPEP2NB

46

A0A0U1RQF7
SYCKNDIRDTVGIWG

APBB2

451

Q92870
NGSWGGRGEVITTYC

ALDH7A1

56

P49419
VEYKNICFTVWDVGG

ARF5

56

P84085
AIDGGWVARTGYCSV

FAT4

3166

Q6V0I7
RTKHICVYWEGSEGG

ADGRE4P

136

Q86SQ3
IYKGLVQTGAWGCFD

DNAH11

1931

Q96DT5
DGWYEGVCNRVTGLF

ABI1

481

Q8IZP0
RYVGETDFAKGEWCG

CLIP2

236

Q9UDT6
GGVDCEWVIVAEEGY

BMP1

886

P13497
EACAVWTGGVYLVAG

RAI1

1826

Q7Z5J4
FGEYCSSENGKGREW

KIAA0513

121

O60268
GIVLCGDEEGNVWLY

LRWD1

566

Q9UFC0
DGKVYDITEWAGCQR

DNAJC14

591

Q6Y2X3
EVYYRGQWGTVCDDG

PRSS12

401

P56730
TEGIWELVTGGVFYC

MMD2

206

Q8IY49
GKGLEWVSVIYSCGS

IGHV3-66

61

A0A0C4DH42
FGEQGVTVGCWDTYR

LOXL4

661

Q96JB6
TRNKEVYSWGCGEYG

NEK9

496

Q8TD19
VGEGRACWSLGNAYV

GPSM1

326

Q86YR5
YVVCNTRQKGTWGPE

LGALS9C

71

Q6DKI2
CRDFIWGVIGKQGYQ

PRKCE

186

Q02156
GYCSGWLVEKVEVTN

LOXHD1

2021

Q8IVV2
LWCVETGEIKREYGG

MLST8

296

Q9BVC4
AKQYGGWEVKCELSG

EXOC2

531

Q96KP1
CGGYNGEVILGDIWK

KLHDC10

331

Q6PID8
SGQFDLGKCEIGWAY

LHFPL6

156

Q9Y693
TINGTWDGDELGYRC

P2RY2

11

P41231
LWYKITGAQVGTGCG

RELN

1461

P78509
EWGDSGVYQCVIKGR

IL1RL2

86

Q9HB29
CHEGGQSYKIGDTWR

FN1

141

P02751
RCNSIKVEGGTWAVY

CRYGS

36

P22914
YWCGIEKTGNDLGVT

CD300LF

106

Q8TDQ1
VLGGCWVGYEKEGFR

CRYBG2

1211

Q8N1P7
EKGVYRNCEDWGAGN

CRYBG2

1321

Q8N1P7
KYILQGVTSWGLGCA

LPA

2001

P08519
KSCRVSGGSWVVYDG

CRYBG1

1446

Q9Y4K1
WFYEKESGGACGITG

GPATCH2

286

Q9NW75
KLWDVSTGQCVYGIQ

FBXW2

171

Q9UKT8
GRVEVLYRGSWGTVC

DMBT1

1391

Q9UGM3
GRVEVLYRGSWGTVC

DMBT1

1651

Q9UGM3
GAATEGCKDGWVYNR

SLC22A20P

101

A6NK97
GETNYISVFKGSGCW

MEP1B

111

Q16820
AKGGDISVCEWYQRV

COX6B1

46

P14854
ESGYGRKSDIWSIGC

MAP3K19

1241

Q56UN5
GKLWCFTVDRGSGVV

TRIM32

491

Q13049
VGFYLGTWRDGNVVC

TRMT2B

171

Q96GJ1
IGQYTSEGGITCWEK

SLC6A6

101

P31641
LVGVVSWGYGCTLRD

PRSS29P

276

A6NIE9
GRCADYVVTGAWSAK

PSAT1

96

Q9Y617
LSKDGYGGWQDLVCL

RNF215

226

Q9Y6U7
QYDGKVDVWSLGITC

TAOK1

201

Q7L7X3
QYDGKVDVWSLGITC

TAOK2

201

Q9UL54
EGKLWVACYNGGRVI

RGN

211

Q15493
KYILQGVTSWGLGCA

PLG

771

P00747
GGTITYKCVGSQWEE

ADGRF5

701

Q8IZF2
VEYKNICFTVWDVGG

ARF4

56

P18085
CVINTCGWVKGSGYQ

CLP1

226

Q92989
TDCTRTGLGGYWGNK

INPP5J

526

Q15735
TRHVYTGGKGCVKVW

TLE1

496

Q04724
QGGDVLEWIQRYGAC

TSSK4

106

Q6SA08
LQVYCDMETDGGGWI

TNN

1096

Q9UQP3
HVYTGGKGCVKVWDI

TLE4

501

Q04727
IGVGGCWFAYTQNKT

STIM2

226

Q9P246
GWEGAKYAVAVGSLC

SLC7A1

331

P30825
GGSYWKEGCLQSELI

SOGA3

246

Q5TF21
SKVTCGRGGWVYVLH

TRMT61A

56

Q96FX7
VYVWYGGQECTGLVE

ZNF395

81

Q9H8N7
GQFTSEGGITCWRKV

SLC6A11

111

P48066
GGDYIVSIQLVDCKW

RHPN2P1

451

A8MT19
RCGGWSAKFVDVQYS

PKHD1L1

2766

Q86WI1
SKGLTVVDVYQGWCG

NME9

26

Q86XW9
VYTGGKGCVKIWDIS

TLE3

501

Q04726
EDGCVYGWETRSGQL

WDR38

41

Q5JTN6
GWEGGVYVQTCGHTL

UBR3

1316

Q6ZT12
GIVSWGEGCDRDGKY

F2

586

P00734
HVYTGGKGCVKVWDV

TLE2

471

Q04725
NGTTIEGHVVKCYWG

TIAL1

261

Q01085
GTTIEGHVVKCYWGK

TIA1

271

P31483
CYGDLVQELWSGTQK

USP32

786

Q8NFA0