Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessprotein K29-linked ubiquitination

UBE2D2 UBE2D3 UBR5 RNF126

5.84e-06132014GO:0035519
DomainDUF1785

AGO2 AGO4 PIWIL2

1.23e-0552023SM01163
DomainArgoL1

AGO2 AGO4 PIWIL2

2.43e-0562023PF08699
DomainArgoL1

AGO2 AGO4 PIWIL2

2.43e-0562023IPR014811
DomainPoly(ADP-ribose)pol_cat_dom

PARP6 PARP1 PARP4 PARP8

2.83e-05172024IPR012317
DomainPARP_CATALYTIC

PARP6 PARP1 PARP4 PARP8

2.83e-05172024PS51059
DomainPARP

PARP6 PARP1 PARP4 PARP8

2.83e-05172024PF00644
Domain-

PARP6 PARP1 PARP4 PARP8

2.83e-051720243.90.228.10
DomainPIWI

AGO2 AGO4 PIWIL2

6.71e-0582023PS50822
DomainPiwi

AGO2 AGO4 PIWIL2

6.71e-0582023SM00950
DomainPiwi

AGO2 AGO4 PIWIL2

6.71e-0582023PF02171
DomainPiwi

AGO2 AGO4 PIWIL2

6.71e-0582023IPR003165
DomainPAZ

AGO2 AGO4 PIWIL2

9.98e-0592023PS50821
DomainPAZ

AGO2 AGO4 PIWIL2

9.98e-0592023SM00949
DomainPAZ

AGO2 AGO4 PIWIL2

9.98e-0592023PF02170
DomainPAZ_dom

AGO2 AGO4 PIWIL2

9.98e-0592023IPR003100
DomainPumilio_RNA-bd

PUM2 PUM1

1.16e-0422022IPR033712
DomainWGR_domain

PARP6 PARP1 PARP4 PARP8

1.19e-04242024IPR008893
DomainEGF_dom

NELL1 STAB2 CUBN

2.55e-04122023IPR024731
DomainEGF_3

NELL1 STAB2 CUBN

2.55e-04122023PF12947
DomainPUF

PUM2 PUM1

3.47e-0432022PF00806
DomainPUM_HD

PUM2 PUM1

3.47e-0432022PS50303
DomainPUM-HD

PUM2 PUM1

3.47e-0432022IPR033133
DomainFAS1

STAB2 POSTN

6.88e-0442022SM00554
DomainFAS1_domain

STAB2 POSTN

6.88e-0442022IPR000782
DomainPARP_ALPHA_HD

PARP1 PARP4

6.88e-0442022PS51060
DomainPoly(ADP-ribose)pol_reg_dom

PARP1 PARP4

6.88e-0442022IPR004102
DomainPUM

PUM2 PUM1

6.88e-0442022PS50302
DomainPumilio_RNA-bd_rpt

PUM2 PUM1

6.88e-0442022IPR001313
Domain-

PARP1 PARP4

6.88e-04420221.20.142.10
DomainArgonaute_N

AGO2 AGO4

6.88e-0442022IPR032474
DomainArgonaute_Mid_dom

AGO2 AGO4

6.88e-0442022IPR032473
DomainArgoL2

AGO2 AGO4

6.88e-0442022IPR032472
Domain-

STAB2 POSTN

6.88e-04420222.30.180.10
DomainFAS1

STAB2 POSTN

6.88e-0442022PS50213
DomainFasciclin

STAB2 POSTN

6.88e-0442022PF02469
DomainArgoN

AGO2 AGO4

6.88e-0442022PF16486
DomainArgoMid

AGO2 AGO4

6.88e-0442022PF16487
DomainArgoL2

AGO2 AGO4

6.88e-0442022PF16488
DomainPumilio

PUM2 PUM1

6.88e-0442022SM00025
DomainRUN

DENND5B RUNDC1 RUBCN

9.02e-04182023SM00593
Domain-

PLPPR3 PLPPR4 G6PC3

9.02e-041820231.20.144.10
DomainacidPPc

PLPPR3 PLPPR4 G6PC3

9.02e-04182023SM00014
DomainRUN

DENND5B RUNDC1 RUBCN

1.06e-03192023PS50826
DomainRUN

DENND5B RUNDC1 RUBCN

1.06e-03192023PF02759
DomainRun_dom

DENND5B RUNDC1 RUBCN

1.06e-03192023IPR004012
DomainEGF

RELN NELL1 FCGBP STAB2 EFEMP2 NTNG1 CUBN SLIT3 LRP1

1.07e-032352029SM00181
DomainP_Acid_Pase_2/haloperoxidase

PLPPR3 PLPPR4 G6PC3

1.24e-03202023IPR000326
DomainPAP2

PLPPR3 PLPPR4 G6PC3

1.24e-03202023PF01569
DomainGrowth_fac_rcpt_

ERBB2 NELL1 STAB2 EFEMP2 CUBN SLIT3 LRP1

1.56e-031562027IPR009030
DomainEGF-like_dom

RELN NELL1 FCGBP STAB2 EFEMP2 NTNG1 CUBN SLIT3 LRP1

1.60e-032492029IPR000742
DomainPH_BEACH

LYST NBEAL2

1.70e-0362022PF14844
Pubmed

Antagonistic and cooperative AGO2-PUM interactions in regulating mRNAs.

AGO2 PUM2 PUM1

2.14e-073209330333515
Pubmed

The mammalian TRIM-NHL protein TRIM71/LIN-41 is a repressor of mRNA function.

AGO2 XRN1 PUM2 PUM1

2.59e-0710209423125361
Pubmed

HIV-1 Vpr protein inhibits telomerase activity via the EDD-DDB1-VPRBP E3 ligase complex.

UBE2D2 UBR5 TERT

2.12e-065209323612978
Pubmed

Family-wide analysis of poly(ADP-ribose) polymerase activity.

PARP6 PARP1 PARP4 PARP8

2.18e-0616209425043379
Pubmed

A ubiquitin ligase complex assembles linear polyubiquitin chains.

UBE2D2 UBE2D3 RNF31

7.36e-067209317006537
Pubmed

Cooperation of HECT-domain ubiquitin ligase hHYD and DNA topoisomerase II-binding protein for DNA damage response.

UBE2D2 UBE2D3 UBR5

7.36e-067209311714696
Pubmed

Hypoxia regulates overall mRNA homeostasis by inducing Met1-linked linear ubiquitination of AGO2 in cancer cells.

AGO2 UBE2D3 RNF31

7.36e-067209334518544
Pubmed

Bifunctional apoptosis regulator (BAR), an endoplasmic reticulum (ER)-associated E3 ubiquitin ligase, modulates BI-1 protein stability and function in ER Stress.

UBE2D2 UBE2D3 UBE2G2

7.36e-067209321068390
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

USP20 ZNF462 LRIG2 PARP4 TNRC18 MYO15B POM121 NTNG1 MAGI3 CGNL1 SPIDR CDC5L DOP1A

1.02e-054932091315368895
Pubmed

Mili interacts with tudor domain-containing protein 1 in regulating spermatogenesis.

AGO2 AGO4 PIWIL2

1.17e-058209319345100
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ERBB2 AGO2 ATRX VPS13C OBSCN ADCY1 ZNF462 TNRC18 INTS2 TLE5 SMYD3 MRPL42 RALGAPB MAGI3 CPT1A INTS8 SBNO2 DNAH1 LATS2 GALNT11 LRP1 SPIDR KDM4B DOP1A

1.18e-0514892092428611215
Pubmed

Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging.

UBA7 UBE2D2 UBE2D3 UBE2G2

1.45e-0525209417597759
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

AGO2 VPS13C P4HA3 TMEM214 POLR1F PARP1 FASN POM121 HIBCH UBR5 MTCH2 DHX37 NOL9 ARAF DCHS1 PUM1

1.49e-057542091635906200
Pubmed

The DNA sequence of human chromosome 7.

MOXD2P RELN CPED1 ADCY1 SEMA3A TNRC18 POM121 CLCN1 ZMIZ2 ANKRD61 GALNT11 ASB4

1.66e-054412091212853948
Pubmed

Inhibition of Poly(ADP-Ribose) Polymerase-1 Protects Chronic Alcoholic Liver Injury.

PARP1 FASN CPT1A

1.75e-059209327746183
Pubmed

Identification of eight members of the Argonaute family in the human genome.

AGO2 AGO4 PIWIL2

1.75e-059209312906857
Pubmed

Targeting ubiquitin conjugating enzyme UbcH5b by a triterpenoid PC3-15 from Schisandra plants sensitizes triple-negative breast cancer cells to lapatinib.

UBE2D2 UBE2D3 RNF126

2.49e-0510209333607208
Pubmed

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.

ADGRB3 PLPPR3 PLPPR4 PCDH19 MAP3K10 ANK2 FASTKD1 MAGI3

2.75e-05197209836604605
Pubmed

Thrombin promotes sustained signaling and inflammatory gene expression through the CDC25 and Ras-associating domains of phospholipase Cϵ.

F2 PLCE1

3.59e-052209226350460
Pubmed

Let-7 Status Is Crucial for PARP1 Expression in HER2-Overexpressing Breast Tumors.

ERBB2 PARP1

3.59e-052209228031413
Pubmed

Cloning and comparative sequence analysis of PUM1 and PUM2 genes, human members of the Pumilio family of RNA-binding proteins.

PUM2 PUM1

3.59e-052209212459267
Pubmed

Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins.

PUM2 PUM1

3.59e-052209229165587
Pubmed

Dual fatty acid synthase and HER2 signaling blockade shows marked antitumor activity against breast cancer models resistant to anti-HER2 drugs.

ERBB2 FASN

3.59e-052209226107737
Pubmed

PUMILIO-mediated translational control of somatic cell cycle program promotes folliculogenesis and contributes to ovarian cancer progression.

PUM2 PUM1

3.59e-052209235507203
Pubmed

Mouse Pum1 and Pum2 genes, members of the Pumilio family of RNA-binding proteins, show differential expression in fetal and adult hematopoietic stem cells and progenitors.

PUM2 PUM1

3.59e-052209212667987
Pubmed

Regulation of telomerase by telomeric proteins.

DKC1 TERT

3.59e-052209215189140
Pubmed

A Quantitative and Predictive Model for RNA Binding by Human Pumilio Proteins.

PUM2 PUM1

3.59e-052209231078383
Pubmed

Clinical and therapeutic relevance of the metabolic oncogene fatty acid synthase in HER2+ breast cancer.

ERBB2 FASN

3.59e-052209227714708
Pubmed

Involvement of poly(ADP-ribose) polymerase 1 in ERBB2 expression in rheumatoid synovial cells.

ERBB2 PARP1

3.59e-052209215743888
Pubmed

Loss of periostin/OSF-2 in ErbB2/Neu-driven tumors results in androgen receptor-positive molecular apocrine-like tumors with reduced Notch1 activity.

ERBB2 POSTN

3.59e-052209225592291
Pubmed

Biophysical and biological evaluation of optimized stapled peptide inhibitors of the linear ubiquitin chain assembly complex (LUBAC).

UBE2D3 RNF31

3.59e-052209229246782
Pubmed

A dyskerin motif reactivates telomerase activity in X-linked dyskeratosis congenita and in telomerase-deficient human cells.

DKC1 TERT

3.59e-052209218057229
Pubmed

TLT-1s, alternative transcripts of triggering receptor expressed on myeloid cell-like transcript-1 (TLT-1), Inhibits the triggering receptor expressed on myeloid cell-2 (TREM-2)-mediated signaling pathway during osteoclastogenesis.

TREML1 TREM2

3.59e-052209222761415
Pubmed

Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE.

PARP1 TLR2

3.59e-052209219684606
Pubmed

Characterization of RNP Networks of PUM1 and PUM2 Post-Transcriptional Regulators in TCam-2 Cells, a Human Male Germ Cell Model.

PUM2 PUM1

3.59e-052209232316190
Pubmed

TERT-mediated and ATRX-mediated Telomere Maintenance and Neuroblastoma.

ATRX TERT

3.59e-052209228452859
Pubmed

A family with Hoyeraal-Hreidarsson syndrome and four variants in two genes of the telomerase core complex.

DKC1 TERT

3.59e-052209223335200
Pubmed

Defects in mTR stability and telomerase activity produced by the Dkc1 A353V mutation in dyskeratosis congenita are rescued by a peptide from the dyskerin TruB domain.

DKC1 TERT

3.59e-052209222855157
Pubmed

Triple-negative breast cancer.

ERBB2 PARP1

3.59e-052209220473728
Pubmed

Genome-wide comparison of human keratinocyte and squamous cell carcinoma responses to UVB irradiation: implications for skin and epithelial cancer.

PUM2 PUM1

3.59e-052209212771951
Pubmed

Poly-(ADP-Ribose) Polymerase-1 Promotes Prothrombin Gene Transcription and Produces Des-Gamma-Carboxy Prothrombin in Hepatocellular Carcinoma.

F2 PARP1

3.59e-052209228384634
Pubmed

Embryonic Lethality in Homozygous Human Her-2 Transgenic Mice Due to Disruption of the Pds5b Gene.

PDS5B ERBB2

3.59e-052209226334628
Pubmed

FASN, ErbB2-mediated glycolysis is required for breast cancer cell migration.

ERBB2 FASN

3.59e-052209226936618
Pubmed

MicroRNA-1224 Splicing CircularRNA-Filip1l in an Ago2-Dependent Manner Regulates Chronic Inflammatory Pain via Targeting Ubr5.

AGO2 UBR5

3.59e-052209230651325
Pubmed

Expressions of fatty acid synthase and HER2 are correlated with poor prognosis of ovarian cancer.

ERBB2 FASN

3.59e-052209225433947
Pubmed

Comparative analysis of mRNA targets for human PUF-family proteins suggests extensive interaction with the miRNA regulatory system.

PUM2 PUM1

3.59e-052209218776931
Pubmed

Paracoccidioides brasiliensis downmodulates α3 integrin levels in human lung epithelial cells in a TLR2-dependent manner.

ITGA3 TLR2

3.59e-052209233173103
Pubmed

Bespoke RNA recognition by Pumilios.

PUM2 PUM1

3.59e-052209226517885
Pubmed

Involvement of HIV-1 protease in virus-induced cell killing.

PARP1 PARP4

3.59e-052209215781132
Pubmed

Interaction between fatty acid synthase and human epidermal growth receptor 2 (HER2) in osteosarcoma cells.

ERBB2 FASN

3.59e-052209225674245
Pubmed

Structure of the HECT C-lobe of the UBR5 E3 ubiquitin ligase.

UBE2D2 UBR5

3.59e-052209223027739
Pubmed

Principles of mRNA control by human PUM proteins elucidated from multimodal experiments and integrative data analysis.

PUM2 PUM1

3.59e-052209232753408
Pubmed

Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells.

ERBB2 FASN

3.59e-052209215235125
Pubmed

Effects of PUMILIO1 and PUMILIO2 knockdown on cardiomyogenic differentiation of human embryonic stem cells culture.

PUM2 PUM1

3.59e-052209232437472
Pubmed

High resolution melting analysis for the identification of novel mutations in DKC1 and TERT genes in patients with dyskeratosis congenita.

DKC1 TERT

3.59e-052209222664374
Pubmed

Differential expression of fatty acid synthase (FAS) and ErbB2 in nonmalignant and malignant oral keratinocytes.

ERBB2 FASN

3.59e-052209218528705
Pubmed

Clinical, electrophysiologic, and genetic study of non-dystrophic myotonia in French-Canadians.

CLCN1 G6PC3

3.59e-052209218337100
Pubmed

Endogenous TLR2 ligand embedded in the catalytic region of human cysteinyl-tRNA synthetase 1.

CARS1 TLR2

3.59e-052209232461342
Pubmed

GSE4, a Small Dyskerin- and GSE24.2-Related Peptide, Induces Telomerase Activity, Cell Proliferation and Reduces DNA Damage, Oxidative Stress and Cell Senescence in Dyskerin Mutant Cells.

DKC1 TERT

3.59e-052209226571381
Pubmed

Expression status of fatty acid synthase (FAS) but not HER2 is correlated with the differentiation grade and prognosis of esophageal carcinoma.

ERBB2 FASN

3.59e-052209223419663
Pubmed

Protein lysine methyltransferase SMYD3 is involved in tumorigenesis through regulation of HER2 homodimerization.

ERBB2 SMYD3

3.59e-052209228639750
Pubmed

DPP3 promotes breast cancer tumorigenesis by stabilizing FASN and promoting lipid synthesis.

FASN DPP3

3.59e-052209238655619
Pubmed

The accumulation and not the specific activity of telomerase ribonucleoprotein determines telomere maintenance deficiency in X-linked dyskeratosis congenita.

DKC1 TERT

3.59e-052209222058290
Pubmed

Alternate modes of cognate RNA recognition by human PUMILIO proteins.

PUM2 PUM1

3.59e-052209221397187
Pubmed

LRP1 Regulates Retinal Angiogenesis by Inhibiting PARP-1 Activity and Endothelial Cell Proliferation.

PARP1 LRP1

3.59e-052209226634655
Pubmed

Poly (ADP-ribose) polymerase inhibition enhances trastuzumab antitumour activity in HER2 overexpressing breast cancer.

ERBB2 PARP1

3.59e-052209225128455
Pubmed

PUMILIO proteins promote colorectal cancer growth via suppressing p21.

PUM2 PUM1

3.59e-052209235338151
Pubmed

Solubility-based genetic screen identifies RING finger protein 126 as an E3 ligase for activation-induced cytidine deaminase.

UBE2D2 UBE2D3 ZMIZ2 RNF126

3.99e-0532209423277564
Pubmed

Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation.

LGALS9C LGALS9B TLR2

4.52e-0512209323817958
Pubmed

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

NLRP7 NXPE4 NKX2-3 IRF5 ARHGAP30 IL1RL2 PLTP SLAMF1 SBNO2 CXCR1

4.65e-053422091023128233
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ERBB2 AGO2 VPS13C ADGRB3 AGO4 PLPPR4 INTS2 NBEAL2 XPO4 SLIT3 LHFPL2 KDM4B

9.53e-055292091214621295
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

CNKSR1 RELN PDE2A ATRX ADGRB3 ZMYM2 NELL1 PARP1 UBA7 OSBPL1A MAP3K10 SMPD3 SMYD3 ANK2 EFEMP2 MAGI3 INTS8 PDLIM5 FBH1 LRP1

1.06e-0412852092035914814
Pubmed

MYCN amplification, TERT rearrangements and ATRX mutations in neuroblastoma: clinicopathological correlates- an Indian perspective.

ATRX TERT

1.07e-043209237460674
Pubmed

Comparable Effects of the Androgen Derivatives Danazol, Oxymetholone and Nandrolone on Telomerase Activity in Human Primary Hematopoietic Cells from Patients with Dyskeratosis Congenita.

DKC1 TERT

1.07e-043209233003434
Pubmed

Galectin-9 regulates follicular helper T cells to inhibit humoral autoimmunity-induced pulmonary fibrosis.

LGALS9C LGALS9B

1.07e-043209233316546
Pubmed

Transcriptional activation of hTERT in breast carcinomas by the Her2-ER81-related pathway.

ERBB2 TERT

1.07e-043209219718948
Pubmed

Protective effect of Galectin-9 in murine model of lung emphysema: Involvement of neutrophil migration and MMP-9 production.

LGALS9C LGALS9B

1.07e-043209228704475
Pubmed

Galectin-9 protein is up-regulated in astrocytes by tumor necrosis factor and promotes encephalitogenic T-cell apoptosis.

LGALS9C LGALS9B

1.07e-043209223836896
Pubmed

Protein composition of catalytically active human telomerase from immortal cells.

DKC1 TERT

1.07e-043209217395830
Pubmed

Sequence and mapping of galectin-5, a beta-galactoside-binding lectin, found in rat erythrocytes.

LGALS9C LGALS9B

1.07e-04320927890611
Pubmed

Galectin-9 Is a Novel Regulator of Epithelial Restitution.

LGALS9C LGALS9B

1.07e-043209232380082
Pubmed

Galectin-9-mediated protection from allo-specific T cells as a mechanism of immune privilege of corneal allografts.

LGALS9C LGALS9B

1.07e-043209223667648
Pubmed

Alternative lengthening of telomeres is the major telomere maintenance mechanism in astrocytoma with isocitrate dehydrogenase 1 mutation.

ATRX TERT

1.07e-043209231960234
Pubmed

Regulatory T Cell-Mediated Suppression of Inflammation Induced by DR3 Signaling Is Dependent on Galectin-9.

LGALS9C LGALS9B

1.07e-043209228877989
Pubmed

Galectin-9 ameliorates immune complex-induced arthritis by regulating Fc gamma R expression on macrophages.

LGALS9C LGALS9B

1.07e-043209219800850
Pubmed

A novel function of human Pumilio proteins in cytoplasmic sensing of viral infection.

PUM2 PUM1

1.07e-043209225340845
Pubmed

RING finger E3 ligase PPP1R11 regulates TLR2 signaling and innate immunity.

UBE2D2 TLR2

1.07e-043209227805901
Pubmed

Increased biglycan in aortic valve stenosis leads to the overexpression of phospholipid transfer protein via Toll-like receptor 2.

PLTP TLR2

1.07e-043209220382708
Pubmed

UBR5 Is Coamplified with MYC in Breast Tumors and Encodes an Ubiquitin Ligase That Limits MYC-Dependent Apoptosis.

UBE2D3 UBR5

1.07e-043209232029551
Pubmed

The functional cobalamin (vitamin B12)-intrinsic factor receptor is a novel complex of cubilin and amnionless.

AMN1 CUBN

1.07e-043209214576052
Pubmed

Noncoding RNA NORAD Regulates Genomic Stability by Sequestering PUMILIO Proteins.

PUM2 PUM1

1.07e-043209226724866
Pubmed

Low-density lipoprotein receptor-related protein 1 polymorphism 663 C > T affects clotting factor VIII activity and increases the risk of venous thromboembolism.

F2 LRP1

1.07e-043209217155964
Pubmed

Oncogenic miR-93-5p/Gal-9 axis drives CD8 (+) T-cell inactivation and is a therapeutic target for hepatocellular carcinoma immunotherapy.

LGALS9C LGALS9B

1.07e-043209237105392
Pubmed

Galectin-9/Tim-3 pathway mediates dopaminergic neurodegeneration in MPTP-induced mouse model of Parkinson's disease.

LGALS9C LGALS9B

1.07e-043209236479526
Pubmed

Profiling Lgals9 splice variant expression at the fetal-maternal interface: implications in normal and pathological human pregnancy.

LGALS9C LGALS9B

1.07e-043209223242525
Pubmed

Galectin-9 in allergic airway inflammation and hyper-responsiveness in mice.

LGALS9C LGALS9B

1.07e-043209219851072
Pubmed

The Role of Galectin-9 as Mediator of Atopic Dermatitis: Effect on Keratinocytes.

LGALS9C LGALS9B

1.07e-043209233923930
Pubmed

Obscurin targets ankyrin-B and protein phosphatase 2A to the cardiac M-line.

OBSCN ANK2

1.07e-043209218782775
Pubmed

Intracellular Galectin-9 Enhances Proximal TCR Signaling and Potentiates Autoimmune Diseases.

LGALS9C LGALS9B

1.07e-043209231969388
Pubmed

The Epac-Phospholipase Cε Pathway Regulates Endocannabinoid Signaling and Cocaine-Induced Disinhibition of Ventral Tegmental Area Dopamine Neurons.

RAPGEF3 PLCE1

1.07e-043209228209735
Cytoband3p21.1

CHDH ASB14 DNAH1 CACNA2D3

4.08e-054220943p21.1
Cytoband13q11-q12

ZMYM2 LATS2

1.23e-044209213q11-q12
Cytoband11p11

F2 ACCS

2.04e-045209211p11
GeneFamilyZinc fingers|Zinc fingers PARP-type|Poly(ADP-ribose) polymerases

PARP6 PARP1 PARP4 PARP8

6.76e-06171364684
GeneFamilyArgonaute/PIWI family

AGO2 AGO4 PIWIL2

2.27e-0581363408
GeneFamilyPhospholipases|C2 domain containing phospholipases

PLCL2 PLA2G4E PLCE1

3.69e-04191363832
GeneFamilyPhospholipid phosphatase related

PLPPR3 PLPPR4

5.53e-04513621127
GeneFamilyCD molecules|C-X-C motif chemokine receptors

CXCR3 CXCR1

8.26e-04613621094
GeneFamilyGuanylate cyclase receptors|DENN/MADD domain containing

DENND4B DENND5B FLCN

8.48e-04251363504
GeneFamilyWD repeat domain containing|BEACH domain containing

LYST NBEAL2

1.95e-03913621230
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC30 ZMYM2 CPED1 NELL1 UBR5 XRN1 MAGI3 LHFPL2 SPIDR

2.75e-0718820996468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC30 ZMYM2 CPED1 NELL1 UBR5 XRN1 MAGI3 LHFPL2 SPIDR

2.75e-0718820997a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC30 ZMYM2 CPED1 NELL1 UBR5 XRN1 MAGI3 LHFPL2 SPIDR

2.75e-0718820999cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA3 SEMA3A RAPGEF3 RXFP2 KLK5 EPHX4 SLIT3 PLCE1

7.63e-071562098abf9dd075b1ca8f613c660cc82f8a5af071fb6ab
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA3 SEMA3A RAPGEF3 RXFP2 KLK5 EPHX4 SLIT3 PLCE1

7.63e-071562098dd41ed918b07fa248da458a629b3c53cb7ea8764
ToppCellILEUM-inflamed-(9)_Neuro_cell|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RELN ADGRB3 KCTD1 ANK2 PCDHB2 ABCA6 DCHS1 ASB4

2.06e-061782098611504b0a9e6318b18fba83787b03f9245c82252
ToppCellILEUM-inflamed-(9)_Enteric_neurons|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RELN ADGRB3 KCTD1 ANK2 PCDHB2 ABCA6 DCHS1 ASB4

2.06e-061782098d9142151819afb0dc22bfb32a9c9dba5f553067d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KCTD1 NELL1 ADAMTS17 ANK2 CPT1A SLC22A2 CGNL1 CACNA2D3

2.06e-061782098dfed0fbf7a73b8a9e00178ec58dc4592b271c344
ToppCellnormal_Lung-Myeloid_cells-pDCs|normal_Lung / Location, Cell class and cell subclass

CPED1 PARP6 MYO15B SMPD3 CXCR3 XPO4 CPT1A RSKR

2.97e-061872098d36751372fd40a46441f07735c9c3c5dcb503f24
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPED1 LYST SEMA3A ZNF462 SMPD3 DNAH1 SLC22A2 CGNL1

3.21e-0618920988e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCell10x5'v1-week_17-19-Lymphocytic_NK-T_NK-CD56_bright_NK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

LGALS9C LGALS9B TKTL1 SLFN5 CXCR3 TRGV9 ZAP70 P2RY11

3.34e-061902098251d50a77e5118a9ad19ea01a7c7c862230ed63c
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN SEMA3A STAB2 ANK2 MROH2A POSTN CACNA2D3 PLCE1

3.34e-061902098f50b9814a1beac67dc042a8c27dfd085ceeda3a6
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN SEMA3A STAB2 ANK2 MROH2A POSTN CACNA2D3 PLCE1

3.34e-061902098a22a510b4a257eb0eaf09c7ae7978d3d2f07a58c
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN SEMA3A STAB2 ANK2 MROH2A POSTN CACNA2D3 PLCE1

3.34e-06190209857c136bf6d7feafb4a220877bed0cc8fdf314db2
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRB3 NELL1 ANK2 EFEMP2 NTNG1 ABCA6 SLIT3 LRP1

3.61e-0619220986f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCell10x5'v1-week_17-19-Lymphocytic_NK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

LGALS9C LGALS9B TKTL1 SLFN5 CXCR3 TRGV9 ZAP70 P2RY11

3.61e-06192209863e815664b228575886396387d2738cd73855759
ToppCell10x5'v1-week_17-19-Lymphocytic_NK-T_NK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

LGALS9C LGALS9B TKTL1 SLFN5 CXCR3 TRGV9 ZAP70 P2RY11

3.61e-061922098095151a4f878944835945f698aa0e3b540ffc8c3
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRB3 CPED1 NELL1 ANK2 NTNG1 ABCA6 SLIT3 LRP1

3.75e-061932098fb28717fadd06c3840636d25409ce80c9254bd34
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRB3 NELL1 ADAMTS17 ANK2 NTNG1 ABCA6 SLIT3 LRP1

3.89e-06194209889b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN ITGA3 ADORA1 RAPGEF3 KLK5 PLTP NTNG1 PLCE1

3.89e-06194209843eb677a76634bb9a48a40e0d607c4936ae64bcc
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RELN ITGA3 RAPGEF3 KLK5 NTNG1 NLRP1 SLIT3 PLCE1

3.89e-0619420981374600957c7d7f0b05fd2c1186f521b9096d4ef
ToppCellCOVID-19|World / Condition, Lineage and Cell class

SLFN5 PARP1 PLTP CXCR3 SLAMF1 ZAP70 TLR2 LHFPL2

4.36e-061972098228f641d79282cc3dc51b95a1f4b0cccfc200735
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NKX2-3 CPED1 SEMA3A NELL1 EFEMP2 POSTN SLIT3 LRP1

4.53e-06198209875d104eead681f6bf47c4dd24913cc768c9a1717
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CPED1 NELL1 ANK2 EFEMP2 NTNG1 ABCA6 SLIT3 LRP1

4.70e-06199209830d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellControl_saline-Mesenchymal_fibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

PLPPR3 NELL1 PLPPR4 EFEMP2 NTNG1 ABCA6 SLIT3 LRP1

4.87e-06200209864ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCellSepsis-Leuk-UTI-Lymphocyte-T/NK-NK|Leuk-UTI / Disease, condition lineage and cell class

LGALS9C ERBB2 LGALS9B TKTL1 TLE5 TRGV9 ZAP70 CXCR1

4.87e-062002098bb37fed4872e71f413ae7c4aa12586fa31075334
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts|Control_saline / Treatment groups by lineage, cell group, cell type

PLPPR3 NELL1 PLPPR4 EFEMP2 NTNG1 ABCA6 SLIT3 LRP1

4.87e-062002098a1fc74c1b27e104895910bc7cdce7ba33d30df7e
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

CPED1 NELL1 PLPPR4 ANK2 NTNG1 ABCA6 SLIT3 LRP1

4.87e-062002098bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCellP28-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RELN PDE2A SEMA3A CXCR3 STAB2 MROH2A PLCE1

2.07e-051772097e96a7e4544710aaab8bd2800ecff9667880a8bf4
ToppCellP28-Endothelial-lymphatic_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RELN PDE2A SEMA3A CXCR3 STAB2 MROH2A PLCE1

2.07e-0517720976e330aa3c87fd640526b746a9deb3b2250d2518c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KCTD1 NELL1 ADAMTS17 ANK2 SLC22A2 CGNL1 CACNA2D3

2.23e-0517920972e49b215b71438400aebb483f2c2c08d5e956961
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KCTD1 NELL1 ADAMTS17 ANK2 SLC22A2 CGNL1 CACNA2D3

2.23e-051792097d0fa700648db8ce76a8aa689879a25048299fa40
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CPED1 NELL1 ADAMTS17 NTNG1 ABCA6 SLIT3 LRP1

2.31e-05180209708ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN NELL1 ASB9 PCDH19 PDLIM5 SLC22A2 PLCE1

2.31e-051802097c6030e725e3d86d5d74a1676330c77ffeceb324f
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

VPS13C PARP1 UBA7 HIBCH CXCR3 XPO4 ZAP70

2.39e-051812097986c036e656f24fe374807e2711cec9e3c83c892
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACRBP CHDH KIF24 USP20 UBA7 AGO4 UBR5

2.39e-051812097e2d03115a87f45a7ddd3ade6b9ac3843639bd41a
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACRBP CHDH KIF24 USP20 UBA7 AGO4 UBR5

2.39e-051812097d8d11ef83c4b8b6a6f5c8728e03059e45a8ad264
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A SLFN5 SEMA3A RAPGEF3 PCDH19 PLTP CH25H

2.48e-051822097ab5761bf9af439231cd0f487b6467e372672a517
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE2A SLFN5 SEMA3A RAPGEF3 PCDH19 PLTP CH25H

2.48e-0518220973b4dbf61ca0fe50efe05449815630e301cb76630
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN OBSCN USH2A STAB2 MROH2A DNAH1 PLCE1

2.66e-0518420972cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN OBSCN USH2A STAB2 MROH2A DNAH1 PLCE1

2.66e-0518420972b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN OBSCN USH2A STAB2 MROH2A DNAH1 PLCE1

2.66e-051842097ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCelldroplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN SEMA3A STAB2 ANK2 MROH2A POSTN PLCE1

2.75e-0518520973a4ae836e882e8d29eb0a2dfab5677f10f2d365f
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC30 KCTD1 RREB1 CFAP65 CFAP54 NPY2R DNAH1

2.75e-05185209705bc89a566b0db90ae06506e067190a4739a0974
ToppCelldroplet-Lung-nan-21m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN SEMA3A STAB2 ANK2 MROH2A POSTN PLCE1

2.75e-051852097224f0b022c21dd40bf1f7503f00b3107ef958975
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRX VPS13C IRF5 SLFN5 LYST PARP1 XRN1

2.75e-0518520977adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell10x3'2.3-week_14-16-Lymphocytic_NK-T_NK-CD56_bright_NK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TKTL1 SLFN5 CXCR3 TRGV9 SLAMF1 ZAP70 P2RY11

2.85e-051862097e0eeef2b9e06324354c5a11a4c6d4c98546f32af
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

RELN NELL1 RXFP2 NTNG1 POSTN SLIT3 CGNL1

2.85e-0518620978915436d09775f2828a7678af203b1082b36e21c
ToppCelldroplet-Lung-LUNG-1m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN KCTD1 SEMA3A SMPD3 ANK2 MROH2A PLCE1

2.95e-0518720979c9ae8725905ba0cfe407878006ed06c2480fb72
ToppCellnormal_Lung-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

PARP6 MYO15B SMPD3 CXCR3 XPO4 CPT1A RSKR

2.95e-051872097a3592f056e1c2f82ba325fea2ecc4dd6c6347c81
ToppCelldroplet-Lung-LUNG-1m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN KCTD1 SEMA3A SMPD3 ANK2 MROH2A PLCE1

2.95e-0518720979e9460e57cdc9cd0a0de2866b140e06d0bc19a8f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KCTD1 NELL1 ADAMTS17 ANK2 SLC22A2 CGNL1 CACNA2D3

2.95e-05187209785e58a312fc325e4063a2d250666b99b8f99beb6
ToppCell10x5'v1-week_17-19-Lymphocytic_T-T_NK-NK_T_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SLFN5 ZNF462 FCGBP ADAMTS17 PARP8 SLAMF1 ZAP70

2.95e-0518720973301e0fca8c436d136c71f1a8fd59b3bb11bdd83
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1|Adult / Lineage, Cell type, age group and donor

ITGA3 NBEAL2 LNX2 MAGI3 CGNL1 CACNA2D3 PLCE1

2.95e-05187209777f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCelldroplet-Lung-1m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN KCTD1 SEMA3A SMPD3 ANK2 MROH2A PLCE1

3.05e-051882097dc52dd2957be3f40001f0a56f3d9ac9d66ea466e
ToppCell10x5'-GI_large-bowel-Myeloid_Monocytic|GI_large-bowel / Manually curated celltypes from each tissue

FCGBP ASB9 TREML1 PLTP TLR2 TREM2 LRP1

3.05e-051882097d0045fdda757d191dabc7853f6a6e99c0e97d93d
ToppCellwk_08-11-Hematologic_Lymphocytic-NK-Intermediate_NK|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

LGALS9C LGALS9B ARHGAP30 TKTL1 CXCR3 TRGV9 ZAP70

3.05e-051882097a8170e4ce6406af9f5ad5317e6e26efa7bc66411
ToppCell10x5'-GI_large-bowel-Myeloid_Monocytic-Classical_monocytes|GI_large-bowel / Manually curated celltypes from each tissue

FCGBP ASB9 TREML1 PLTP TLR2 TREM2 LRP1

3.05e-0518820970bcf04aa47738f43c1a87dae5dc487738ee86f8c
ToppCelldroplet-Lung-1m-Endothelial-lymphatic_endothelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN KCTD1 SEMA3A SMPD3 ANK2 MROH2A PLCE1

3.05e-0518820972ef08313087e91985bcffc46c3798470cdeec49c
ToppCelldroplet-Lung-1m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN KCTD1 SEMA3A SMPD3 ANK2 MROH2A PLCE1

3.05e-0518820971f1604b6dc0a8ad0be3d9aac0bef448459c22465
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NELL1 ANK2 EFEMP2 NTNG1 ABCA6 SLIT3 LRP1

3.16e-051892097a153b83314cf52808f685296cff8c95af3f4983d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KCTD1 ITGA3 NELL1 NBEAL2 ADAMTS17 ABCA6 CACNA2D3

3.16e-051892097e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPED1 LYST SEMA3A ZNF462 DNAH1 SLC22A2 CGNL1

3.16e-051892097fb2253b8463d08b3d28e952a31a23dea2c2d986b
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RELN PDE2A P4HA3 SEMA3A STAB2 ANK2 ABCA6

3.27e-0519020979ce301841ce9486701fa28eb2a9929e35d476878
ToppCellTracheal-10x3prime_v2-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

NLRP7 NXPE4 DENND5B TERT SLAMF1 CBY2 FCRL5

3.38e-051912097da4062a0f6d0af6d330acf11da216c64b0fa7c73
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRB3 NELL1 ANK2 NTNG1 ABCA6 SLIT3 LRP1

3.38e-051912097b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellfacs-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN PDE2A SEMA3A STAB2 ANK2 CACNA2D3 PLCE1

3.38e-05191209748823a97c38263f2c6e58348214f5b62773a6368
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN PDE2A SEMA3A STAB2 ANK2 CACNA2D3 PLCE1

3.38e-0519120970eedc66e967b1837ce2c14f8c14b3c1eba868c76
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CPED1 NELL1 ANK2 NTNG1 ABCA6 SLIT3 LRP1

3.49e-0519220973d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NELL1 ADAMTS17 ANK2 EFEMP2 ABCA6 SLIT3 LRP1

3.49e-051922097ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NELL1 ANK2 EFEMP2 NTNG1 ABCA6 SLIT3 LRP1

3.49e-051922097dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CPED1 NELL1 ADAMTS17 ANK2 EFEMP2 SLIT3 LRP1

3.49e-051922097162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellbackground-NK_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

ARHGAP30 SLFN5 PLCL2 PARP8 TRGV9 ZAP70 P2RY11

3.61e-051932097f8d6eff1e04926f85d265ec39fe66897fe29574d
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-NK_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGAP30 SLFN5 CXCR3 PARP8 TRGV9 ZAP70 P2RY11

3.61e-051932097044fba87c4d10f4943a9f57315920280a4d097e7
ToppCell10x5'v1-week_14-16-Lymphocytic_NK-T_NK-CD56_bright_NK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

LGALS9C LGALS9B TKTL1 SLFN5 CXCR3 PARP8 ZAP70

3.61e-05193209746f94a1062b098205e8ce3ed380c0202a4d97678
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CPED1 NELL1 ANK2 EFEMP2 ABCA6 SLIT3 LRP1

3.73e-0519420976e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCell10x5'v1-week_14-16-Lymphocytic_NK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

LGALS9C LGALS9B TKTL1 SLFN5 CXCR3 PARP8 ZAP70

3.73e-0519420975a859885c0f9b8554b0d203e371c70928ad4418f
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-Activated_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGAP30 SLFN5 CXCR3 PARP8 TRGV9 SLAMF1 ZAP70

3.73e-051942097e3705346755cbf65fc276d4d4fbee936ed6bb7bf
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_EM-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLFN5 GCSAM KLK5 CXCR3 PARP8 SLAMF1 ZAP70

3.73e-051942097c49f3341a19128855f084bcf18ef3da4bab79099
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRB3 NELL1 ANK2 NTNG1 ABCA6 SLIT3 LRP1

3.73e-05194209760622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell10x5'v1-week_14-16-Lymphocytic_NK-T_NK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

LGALS9C LGALS9B TKTL1 SLFN5 CXCR3 PARP8 ZAP70

3.73e-0519420977d35ac70ba966eb1fee4197f7de6d6116326a442
ToppCellLeuk-UTI-Lymphocyte-T_NK-NK|Leuk-UTI / Disease, Lineage and Cell Type

LGALS9C ERBB2 LGALS9B TKTL1 TRGV9 ZAP70 CXCR1

3.73e-05194209736afc4e48d267be3b8aa1e33fad043bcd54c6bc5
ToppCellMonocytes-M2-like_CD16+_macrophages|World / Immune cells in Kidney/Urine in Lupus Nephritis

CPED1 OSBPL1A PLTP CH25H TLR2 TREM2 LRP1

3.85e-05195209710fa47bdcf6c9784ea930b75a5861e139421feed
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RELN ITGA3 KLK5 PLTP NTNG1 SLIT3 PLCE1

3.98e-051962097545d2e4469924d333e3f655f559c899fa1260196
ToppCellPCW_13-14-Mesenchymal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ADGRB3 SEMA3A NTNG1 POSTN ABCA6 SLIT3 LRP1

4.11e-05197209773a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCellmild-Plasmablast|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CNKSR1 PRSS16 TMEM214 HIBCH DENND5B TERT FCRL5

4.24e-051982097b14b9e67815f93fac7bd8e5e6f1aa100951b4ac1
ToppCellHealthy-NK|World / disease group, cell group and cell class

ERBB2 LGALS9B TKTL1 SLFN5 TLE5 ZAP70 CXCR1

4.24e-051982097517e49669e13e428aa66081a0ce83c30f3b9b08b
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RELN ITGA3 RAPGEF3 KLK5 PLTP SLIT3 PLCE1

4.38e-051992097b9338b739162cd8e5661c9a4dcb41a31219b5723
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ADAMTS17 ANK2 EFEMP2 NTNG1 ABCA6 SLIT3 LRP1

4.38e-051992097a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RELN ITGA3 RAPGEF3 KLK5 PLTP SLIT3 PLCE1

4.38e-051992097c972d3036151403f26fa9d6271520639c281ab84
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

NELL1 ANK2 EFEMP2 NTNG1 ABCA6 SLIT3 LRP1

4.52e-0520020979b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellBronchial-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADGRB3 CPED1 ANK2 NTNG1 ABCA6 SLIT3 LRP1

4.52e-052002097389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCellBiopsy_Other_PF-Immune-NK_cells|Biopsy_Other_PF / Sample group, Lineage and Cell type

LGALS9C LGALS9B TKTL1 PARP8 TRGV9 ZAP70 CXCR1

4.52e-052002097418d665b8431697fc9e516258c9fe374257750d9
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADGRB3 CPED1 ANK2 NTNG1 ABCA6 SLIT3 LRP1

4.52e-052002097cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_submucosal-gland-SMG_Serous|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PRSS16 IL1RL2 LRIG2 ADORA1 FCGBP DENND4B SMYD3

4.52e-05200209761bae10c8b12196d9cee766897971b81cb897191
ToppCell(61)_LYVE1_Macrophage|World / shred on Cell_type and subtype

NELL1 OSBPL1A PLTP ABCA6 TLR2 TREM2 LRP1

5.45e-052062097711e961a9a03bfd2f0958bd14f25f7f207a2f2b5
ToppCellLPS-IL1RA-Stromal_mesenchymal-Fibroblasts|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PGAP3 TKTL1 F2 MROH2A ABCA6 SUSD2

6.60e-05146209686cddd0e7f954547b7ffdccb0329cd5c4b725ac1
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ACRBP RAPGEF3 KLK5 STAB2 SLIT3 PLCE1

7.39e-051492096cc6224c6b79f43b97adc1ce48ca4906bff2ad318
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CNKSR1 SDE2 NELL1 VWA5B1 C15orf61 MMD

7.39e-05149209661d84838a841ed2d6b8c5f86d423a4e6b3dcc9cb
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ACRBP RAPGEF3 KLK5 STAB2 SLIT3 PLCE1

7.39e-05149209624a7538b54b2a5291503c7493fefed4e45e8d710
Diseasesymmetrical dimethylarginine measurement

NELL1 PLCL2 SMYD3

2.54e-0592013EFO_0006523
DiseaseMitochondrial DNA Deletion Syndromes

SUCLG1 FBXL4 DGUOK

2.54e-0592013cv:CN043632
DiseaseColorectal Carcinoma

ETFDH OBSCN ADORA1 NELL1 PARP1 ANK2 PARP8 NTNG1 CUBN POSTN ABCA6 TLR2 DCHS1 LRP1 FLCN EDRF1

2.79e-0570220116C0009402
DiseaseCryptorchidism

ATRX RXFP2 PUM1

3.61e-05102013C0010417
Diseaselevel of triggering receptor expressed on myeloid cells 2 in blood serum

TREML1 TREM2

4.62e-0522012OBA_2043927
DiseaseMalignant neoplasm of breast

ERBB2 PDE2A OBSCN SEMA3A PARP1 FASN CLCN1 ACCS TREML1 PGBD3 ANK2 CUBN CPT1A TERT SLAMF1 ARAF NCOA1 PACC1 FCRL5 DOP1A

4.94e-05107420120C0006142
Diseasepulse pressure measurement

CWF19L2 DDAH1 CCDC30 ETFDH IRF5 RREB1 FASN RXFP2 MTCH2 CEP97 ANK2 INTS8 RNF126 PDLIM5 LATS2 SLC22A2 SLIT3 LRP1 LHFPL2 KDM4B RSKR PLCE1

2.22e-04139220122EFO_0005763
DiseaseMitochondrial DNA depletion syndrome, encephalomyopathic form

SUCLG1 FBXL4

2.75e-0442012cv:C4707428
Diseasecognitive decline measurement, disease progression measurement

PARP6 UBR5

2.75e-0442012EFO_0007710, EFO_0008336
Diseaseperiostin measurement

STAB2 POSTN

2.75e-0442012EFO_0020628
Diseasekidney failure (biomarker_via_orthology)

PARP1 SLC22A2 TLR2

2.78e-04192013DOID:1074 (biomarker_via_orthology)
Diseasecorpus callosum posterior volume measurement

SEMA3A CFAP54 ATP13A2 LHFPL2

4.38e-04522014EFO_0010298
Diseasegallbladder carcinoma (is_implicated_in)

UBR5 TERT

4.56e-0452012DOID:4948 (is_implicated_in)
DiseaseObesity

ETFDH F2 PARP1 FASN RAPGEF3 MTCH2 SLC22A2

5.36e-042052017C0028754
DiseaseIGF-1 measurement

VPS13C RREB1 ADCY1 ZNF462 ZMIZ2 DENND5B STAB2 SLC22A2 SLIT3 CDC5L KDM4B

5.57e-0448820111EFO_0004627
Diseasecorpus callosum volume measurement

SEMA3A POLR1F NELL1 MTCH2 ATP13A2

6.22e-041002015EFO_0010299
Diseasecortical thickness

PDS5B RELN DDAH1 RREB1 CPED1 SEMA3A ZNF462 POLR1F NELL1 MTCH2 ATP13A2 CBY2 LRP1 ATOH1 CDC5L KDM4B CACNA2D3 PLCE1

6.46e-04111320118EFO_0004840
Diseaseurinary tract infection (is_implicated_in)

TLR2 CXCR1

6.80e-0462012DOID:0080784 (is_implicated_in)
DiseaseAgouti-related protein measurement

SMPD3 ABCA6 CDH16

8.07e-04272013EFO_0008016
DiseaseX-Linked Dyskeratosis Congenita

DKC1 TERT

9.48e-0472012C1148551
Diseasecolorectal cancer

ADGRB3 NKX2-3 RREB1 RXFP2 DENND5B CUBN TERT ZAP70 SBNO2 LRP1 ATOH1 PUM1

9.52e-0460420112MONDO_0005575
DiseaseHematopoetic Myelodysplasia

ATRX SMPD3 TLR2

9.99e-04292013C2713368
DiseaseParkinsonian Disorders

LYST PARP1 ATP13A2

1.10e-03302013C0242422
Diseasecardiomyopathy (implicated_via_orthology)

ERBB2 ARAF PDLIM5 LRP1

1.42e-03712014DOID:0050700 (implicated_via_orthology)
Diseasechylomicron measurement, triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement

RXFP2 PLTP SLC22A2

1.59e-03342013EFO_0008317, EFO_0008596, EFO_0020947
Diseaseunderweight body mass index status

ADGRB3 ANK2

1.61e-0392012EFO_0005936
DiseaseDisorder of fatty acid metabolism

ETFDH CPT1A

1.61e-0392012cv:C0268634
DiseaseDyskeratosis congenita

DKC1 TERT

1.61e-0392012cv:C0265965
Diseasehepatitis C (is_marker_for)

IRF5 F2 TERT

1.74e-03352013DOID:1883 (is_marker_for)
DiseaseHOYERAAL-HREIDARSSON SYNDROME

DKC1 TERT

2.00e-03102012C1846142
Diseasealpha wave measurement, electroencephalogram measurement

DNAH1 TFB1M

2.00e-03102012EFO_0004357, EFO_0006870
Diseaseosteoarthritis, hand

F2 CFAP54 CDC5L

2.04e-03372013EFO_1000789
Diseasenitric oxide exhalation measurement

SMYD3 ANK2 CACNA2D3

2.20e-03382013EFO_0005536
Diseaserheumatoid arthritis, Crohn's disease

NKX2-3 LRIG2 MAGI3

2.20e-03382013EFO_0000384, EFO_0000685
Diseasedilated cardiomyopathy (implicated_via_orthology)

ERBB2 MTCH2 CXCR3 PDLIM5

2.21e-03802014DOID:12930 (implicated_via_orthology)
Diseasepeak expiratory flow

RREB1 UBA7 XRN1 ADAMTS17 MTCH2 ASB14 ATP13A2 LRP1 NCOA1 CACNA2D3

2.32e-0349820110EFO_0009718
Diseasecorpus callosum anterior volume measurement

SEMA3A POLR1F CBY2

2.38e-03392013EFO_0010295
Diseaseliver cirrhosis (is_marker_for)

RELN IRF5 F2 PARP1

2.42e-03822014DOID:5082 (is_marker_for)
Diseasegastric adenocarcinoma (is_implicated_in)

UBR5 PLCE1

2.44e-03112012DOID:3717 (is_implicated_in)
Diseasecongenital diaphragmatic hernia (implicated_via_orthology)

SLIT3 LRP1

2.91e-03122012DOID:3827 (implicated_via_orthology)
DiseaseMyeloproliferative disease

ZMYM2 TERT

2.91e-03122012C0027022
DiseaseSchizophrenia

RELN PRSS16 F2 CFAP65 SEMA3A ADORA1 PLCL2 NTNG1 PDLIM5 SBNO2 TLR2 SLIT3 LRP1 CGNL1

3.06e-0388320114C0036341
DiseaseChildhood Medulloblastoma

ERBB2 ATOH1 KDM4B

3.14e-03432013C0278510
DiseaseMelanotic medulloblastoma

ERBB2 ATOH1 KDM4B

3.14e-03432013C1275668
DiseaseMedullomyoblastoma

ERBB2 ATOH1 KDM4B

3.14e-03432013C0205833
DiseaseDesmoplastic Medulloblastoma

ERBB2 ATOH1 KDM4B

3.14e-03432013C0751291
DiseaseAdult Medulloblastoma

ERBB2 ATOH1 KDM4B

3.14e-03432013C0278876
Diseasehigh grade glioma (implicated_via_orthology)

F2 CXCR3 ARAF

3.36e-03442013DOID:3070 (implicated_via_orthology)
Diseaselung disease (implicated_via_orthology)

ADORA1 TLR2

3.43e-03132012DOID:850 (implicated_via_orthology)
DiseaseProstatic Neoplasms

ERBB2 ACRBP TBC1D2 PARP1 KLK5 STAB2 RNF31 EFEMP2 TERT NCOA1 ALOXE3

3.50e-0361620111C0033578
DiseaseMalignant neoplasm of prostate

ERBB2 ACRBP TBC1D2 PARP1 KLK5 STAB2 RNF31 EFEMP2 TERT NCOA1 ALOXE3

3.50e-0361620111C0376358
Diseasehomocysteine measurement

POLR1F CUBN MMACHC

3.81e-03462013EFO_0004578
Diseasepulmonary emphysema (is_marker_for)

SMPD3 CXCR3

3.98e-03142012DOID:9675 (is_marker_for)
Diseasecalcium measurement

ZMYM2 RREB1 TLE5 A4GALT MTCH2 CARS1 CPT1A ABCA6 SLC22A2 CGNL1 PLCE1

4.04e-0362820111EFO_0004838
DiseaseAdenocarcinoma of large intestine

ERBB2 UBR5 ARAF FLCN

4.26e-03962014C1319315
Diseaselung adenocarcinoma (is_implicated_in)

ERBB2 UBR5 TERT

4.56e-03492013DOID:3910 (is_implicated_in)
DiseaseMitochondrial disease

SUCLG1 FBXL4 DGUOK

4.56e-03492013cv:C0751651
DiseaseMedulloblastoma

ERBB2 ATOH1 KDM4B

4.82e-03502013C0025149
Diseaseosteosarcoma (is_implicated_in)

EFEMP2 CDC5L

5.20e-03162012DOID:3347 (is_implicated_in)
DiseaseDyskeratosis Congenita

DKC1 TERT

5.20e-03162012C0265965
Diseasecholesterol in small VLDL measurement

PLTP ABCA6 SLC22A2

5.68e-03532013EFO_0022228
DiseaseBenign neoplasm of stomach

ERBB2 UBR5

5.87e-03172012C0153943
Diseaseallergic rhinitis (is_marker_for)

F2 TLR2

5.87e-03172012DOID:4481 (is_marker_for)
DiseaseNeoplasm of uncertain or unknown behavior of stomach

ERBB2 UBR5

5.87e-03172012C0496905
DiseaseCarcinoma in situ of stomach

ERBB2 UBR5

5.87e-03172012C0154060
Diseasecervical artery dissection

LRP1 PLCE1

5.87e-03172012EFO_1000059
Diseaseperinatal necrotizing enterocolitis (biomarker_via_orthology)

PARP1 TLR2

5.87e-03172012DOID:8677 (biomarker_via_orthology)
DiseaseAcute Cerebrovascular Accidents

F2 CXCR3 ANK2

5.98e-03542013C0751956
DiseaseMajor Depressive Disorder

RELN NELL1 TERT PDLIM5 SLIT3 LRP1

6.59e-032432016C1269683
Diseasepeptide measurement

NELL1 NLRP1 CNEP1R1 CACNA2D3

6.67e-031092014EFO_0010520

Protein segments in the cluster

PeptideGeneStartEntry
THCQYNFPQVGRTAL

CXCR3

201

P49682
VLQGLPREYVNARHC

ERBB2

546

P04626
TQCYGLLAPIIYHNI

CFAP54

1151

Q96N23
APIIGRTAAQCLEHY

CDC5L

86

Q99459
LTYCPQIRILLFHGC

AMN1

216

Q8IY45
HLGTPLYLACENQQR

ASB9

166

Q96DX5
YHVRGPINQVCSEIL

CPED1

1001

A4D0V7
GAITQHVCLYGNIRL

ACCS

196

Q96QU6
RHLGISLLSCFPNVQ

A4GALT

126

Q9NPC4
AILINIGPQTYFHTC

ADORA1

66

P30542
ELAHLANGTLNPYCV

ADGRB3

806

O60242
AAQPEICYQLLLNHG

ASB4

301

Q9Y574
HGCRNPTLVQLDQYE

ACRBP

66

Q8NEB7
LGYHLSLHRNEICNP

ABCA6

706

Q8N139
SVLGHLGYCPQENVL

ABCA6

1351

Q8N139
PHGNLIRLAVNELFC

C14orf28

181

Q4W4Y0
YILPTHIQAARAGNA

CPT1A

261

P50416
LHGFIYLQASPQVCL

DGUOK

186

Q16854
AHNAPSYRACVQLLS

DOP1A

2081

Q5JWR5
YTLINHRVLCTRPSG

GCSAM

86

Q8N6F7
SNKRSPLHLAIAYGC

ANKRD61

166

A6NGH8
LRHGANVNYFCRVNP

ASB14

406

A6NK59
HTYLPLEVCNIVAGQ

AGO4

326

Q9HCK5
QLQNGTHVATRPLYC

ADAMTS17

891

Q8TE56
HTYLPLEVCNIVAGQ

AGO2

336

Q9UKV8
YIQQACTRPITLHSA

CHDH

341

Q8NE62
RQVCQLPGLFSYAQH

MTCH2

46

Q9Y6C9
QCYLGRFNDIHVPIR

PDS5B

316

Q9NTI5
QQLTPYSQVHICLRS

INTS8

321

Q75QN2
QVFVLSTHPYGCRVI

PUM2

876

Q8TB72
NYCHTSQGDPIGLIL

PARP1

906

P09874
NAVGSCQKPYVALIH

HIBCH

126

Q6NVY1
VLCHLVPYAQGLAVQ

NPY2R

121

P49146
NIPHLQTRDTYEGLC

P4HA3

291

Q7Z4N8
VLLGIAQASCQPRHY

PCDHB2

21

Q9Y5E7
VHQAICNLNITLPIY

ANK2

1441

Q01484
YHQQTLPLGCRRSES

PCDH19

816

Q8TAB3
NRYLINHLLNSLPCV

NOL9

316

Q5SY16
QCDRYQLQLLAHDGP

DCHS1

2341

Q96JQ0
VALVAQLRFCGPNHI

OR11A1

161

Q9GZK7
RLHCSLTQYLNGPVP

PARP8

211

Q8N3A8
TCISLNRYLGIVHPF

P2RY11

121

Q96G91
ALQHPNIIALRGACL

MAP3K10

151

Q02779
PHYTLLITGLCRFQI

LONP2

96

Q86WA8
SRHNQNLGCYPVELE

MAGI3

1011

Q5TCQ9
EAYRCNFLGLSPHVQ

FLCN

411

Q8NFG4
QRCLAHSLVGTPNYI

LATS2

866

Q9NRM7
QPLCQYRAATIHHRL

EDRF1

1016

Q3B7T1
GPINHYRNIFSCLPL

EPHX4

276

Q8IUS5
RVFCLLAVAPGAHSQ

IGHV1-46

6

P01743
GTVLPSAQRFHINLC

LGALS9C

246

Q6DKI2
LAEAPTHCLNGRQQY

ALOXE3

331

Q9BYJ1
THCLNGRQQYVAAPL

ALOXE3

336

Q9BYJ1
QGPCSHLCLINYNRT

LRP1

1546

Q07954
RGPAVSLQHYCVNFS

CFAP65

461

Q6ZU64
RLAFGNHYQPQTLCI

KIAA1109

211

Q2LD37
GTVLPSAQRFHINLC

LGALS9B

246

Q3B8N2
LGIALHSPCYAQVRR

G6PC3

261

Q9BUM1
HSPCYAQVRRAQLGN

G6PC3

266

Q9BUM1
HNYARAVLSQPCNTL

LNX2

296

Q8N448
NQQICPVLYHAGTVL

PLTP

181

P55058
CEAQRGSLPILYQFH

FCRL5

401

Q96RD9
TLHCEVQRGSPQILY

FCRL5

491

Q96RD9
NRTGAVYLCPLTAHK

ITGA3

86

P26006
IRFPLNGYCHLNSVQ

KCTD1

191

Q719H9
GHSILCRSQQYPAAR

PDE2A

6

O00408
CLHYLAQALQAQPLG

NLRP1

551

Q9C000
VYLCLPNVRSLTEGH

CWF19L2

696

Q2TBE0
EGNANPTHRLLCYLL

FAM214B

471

Q7L5A3
YHLQTNKCLVAQGRP

GALNT11

486

Q8NCW6
ANITGFLPIHCIYQL

INTS2

546

Q9H0H0
PRHGQTNILVYITIC

NIPA2

171

Q8N8Q9
RSQLQLYLTCHGPTA

KIF24

1346

Q5T7B8
QVHASCYGIRPELVN

KDM4B

766

O94953
SRHVPQGAQAYTICG

RSKR

251

Q96LW2
RPLAGTIVYCAQHLT

LMLN2

276

A0A1B0GTW7
LGIYARCIRNPGVQH

LHFPL2

61

Q6ZUX7
AESVGLYLCLHPQVL

DPP3

511

Q9NY33
QAARQVHLCRGVFPL

PKLR

501

P30613
LRPNQLYCGAVLVHP

KLK5

86

Q9Y337
ISNPHGCRLFYSQLE

IRF5

266

Q13568
AHCNQVIRGPFLVAL

PDLIM5

421

Q96HC4
HGALQAILTFRLPYC

OR10G3

156

Q8NGC4
NDRLLVYGFIPHCTQ

PARP4

1081

Q9UKK3
QRIVGYIACTHLHAP

SMPD3

451

Q9NY59
PLHLACYFGHRQVVQ

OSBPL1A

51

Q9BXW6
QCVAYHLGRVRESLP

MMACHC

81

Q9Y4U1
HANTVCVNLPGLYRC

NELL1

446

Q92832
LEPGQQCLTTHAYLG

LY6G6C

41

O95867
NCYTHAFLIVPAIVG

MMD

31

Q15546
PTNVECSRYHLQRIL

RELN

2416

P78509
QVFALSTHPYGCRVI

PUM1

996

Q14671
IALYPGQAQLLSCKH

PACC1

116

Q9H813
DRHAAICNPLLYSGT

OR9G4

136

Q8NGQ1
QGCVPRHSVIRSLFY

OBSCN

6861

Q5VST9
ISVPLLAAQRHYCSQ

OR56B2P

166

Q8NGI1
LGRSHVYFIQCLTPN

MYO15B

221

Q96JP2
PILAAQRHYCSRNEI

OR56B4

166

Q8NH76
LIIHLNYCAGSQTKP

PLA2G4E

721

Q3MJ16
RYPIHQAQYSCLGVL

POM121

231

Q96HA1
CHAGVSTAYIILQLP

IL1RL2

316

Q9HB29
PVQLLQHTPCYRTAG

IL1RL2

546

Q9HB29
RLHNLYSTPRCAQQA

CBY2

61

Q8NA61
PSIHARLIGAYCGTQ

CUBN

1916

O60494
LTQRPQVGCYIHGLF

DNAH1

4156

Q9P2D7
VRNIRPSCHGVLGVY

ETFDH

451

Q16134
CVLYLHITRVQCFPG

ADCY1

651

Q08828
SLPYSHIGCRDQIIF

ARAF

506

P10398
CGTLILQARAYVGPH

ATP13A2

376

Q9NQ11
LTGTPLQNNLIEYHC

ATRX

1746

P46100
ACVRQHLPDLYAAAG

FBH1

326

Q8NFZ0
LHYVEPCLNGTLVQA

CACNA2D3

301

Q8IZS8
GHPYIVLNNTERCLA

CGNL1

51

Q0VF96
YHPGAVIRILACSAN

FBXL4

146

Q9UKA2
YVLAQTCGTRPGLHR

FCGBP

1276

Q9Y6R7
VYVLAQTCGTRPGLH

FCGBP

2476

Q9Y6R7
GQHIQLVQYLATVCP

CEP97

261

Q8IW35
TCVQHLNSYLGILDP

FASTKD1

596

Q53R41
GICTARAAQYLLHSP

ATOH1

71

Q92858
LHSCLNPIIYAFIGQ

CXCR1

296

P25024
SELICLYNEVHNLPG

CCDC30

46

Q5VVM6
CHYVNAINTAPRNIG

DENND5B

1186

Q6ZUT9
NRLCYVQSLAGHKSP

LYST

3646

Q99698
QLTSPRFQCGYVLLH

MARCHF11

361

A6NNE9
QLCSHYGQPVLSVRV

DENND4B

821

O75064
SCHCPQGYQLLATRL

EFEMP2

266

O95967
AYQAIHSGQCPAAIV

FASN

171

P49327
KLNVRTTHYTPLACG

DKC1

61

O60832
SRQHGCLPYAITIVA

DHX37

791

Q8IY37
QYHCLSAQLRPLLGD

RUBCN

131

Q92622
TVQHGAVYSLEPRLC

SDE2

61

Q6IQ49
ELYPTFIRNLGVHIC

SLC22A2

456

O15244
GLCPQGYVHTVLRDS

NKX2-3

86

Q8TAU0
AQQLLPCLGQTLYQH

CH25H

81

O95992
NCIYLNIPNKGHVLL

DDAH1

221

O94760
PSQYLCTPRQDHGLI

CDH16

671

O75309
HLVQLPNINRVSTCY

PPEF2

156

O14830
VQGSCAADLYRHPQL

PARP6

26

Q2NL67
RCAGVHISDPYNVNL

ARHGAP30

406

Q7Z6I6
YLCCVRTVGLQHPAV

PGAP3

181

Q96FM1
AGIHPLCLVSRYSQK

PGBD3

426

Q8N328
HHILVYACGNASVLP

MOXD2P

241

A6NHM9
VASYCHPQLLLNLVD

MROH2A

786

A6NES4
HNNVRCLCPAAYTGI

NTNG1

481

Q9Y2I2
LFNTYEHLLPGNARC

RETSAT

356

Q6NUM9
NLICKSGSLIEPHYQ

RUNDC1

556

Q96C34
VQRQVAHCLAAYAPR

TSGA10IP

411

Q3SY00
HGRLYLRTPGNVTNC

USH2A

2571

O75445
GQVHCVSPLLYESGR

SUSD2

111

Q9UGT4
PAGTQPCRLHLYNSL

CARS1

21

P49589
LFNHPNILRLVAYCL

STK16

71

O75716
NPRDTYCRGDQLHIL

NXPE4

106

Q6UWF7
LTQHTACQLLRTYPA

PLCE1

1776

Q9P212
GIPTHYVCVLNTANL

PIWIL2

901

Q8TC59
QYPHFRCRTNVLGSI

NARS2

141

Q96I59
INDPALRHTGLYCNQ

NCOA1

1356

Q15788
IPQITRNHSGLYACS

PSG9

381

Q00887
CRQLFHLIYGQPDVV

NBEAL2

1261

Q6ZNJ1
CLQTGYRHVPLQSLT

PLCL2

851

Q9UPR0
YALGERVRQLPCNHL

RNF126

236

Q9BV68
LTLGPQHADNIYICT

SLAMF1

196

Q13291
YLNHNCITTLRPGIF

RXFP2

191

Q8WXD0
LCVYGAGHLEQPQIS

TRGV9

16

Q99603
QYLCNVRHIFTIPGQ

TFB1M

201

Q8WVM0
TYACQQHEVLLPSGQ

SBNO2

256

Q9Y2G9
CNLQYLRLGGHCATP

NLRP7

761

Q8WX94
TAGVAQLPLHRCDIY

SEMA3A

506

Q14563
RLTEYIHCLQPATGR

CNEP1R1

16

Q8N9A8
RHPSLNGYLQCHIQL

MTRF1

11

O75570
NCSIVFNGPHLLLRA

SMYD3

211

Q9H7B4
FLLPQNGIRHCSYTA

SUCLG1

31

P53597
LCVANTHILYNPRRG

ANGEL1

386

Q9UNK9
AGQRPSIFQSLLHCL

CLCN1

761

P35523
HLITCISKYQSPGRA

CNKSR1

496

Q969H4
PVQGANYHVLRTGCF

C15orf61

71

A6NNL5
NGICAQVLPYLSQEH

TLE5

86

Q08117
LVRCNAHGEPRNYLN

RNF31

56

Q96EP0
LSYNRLRCIPVHAFN

SLIT3

806

O75094
IICGLTRITQYKNHP

PLPPR4

291

Q7Z2D5
RGNRPHIYCLEQLLQ

TNRC18

2196

O15417
TPDQLGNISLRHYLC

UHRF1BP1L

1221

A0JNW5
GNISLRHYLCNRPVG

UHRF1BP1L

1226

A0JNW5
TRIYHPNINSNGSIC

UBE2D2

71

P62837
YQLLLEHQRPSCIQG

RAPGEF3

56

O95398
HQLDNPYIVRLIGVC

ZAP70

391

P43403
YIQCHLAAPDGTRNL

XPO4

436

Q9C0E2
VVAAASLRCQNYGIP

UBA7

821

P41226
HVRSHLGISPYQCNI

RREB1

661

Q92766
GVCGLTQITQYRSHP

PLPPR3

246

Q6T4P5
LCYILTAHPNLGQID

SPIDR

601

Q14159
LKHLFPVQNGALYCV

MRPL42

16

Q9Y6G3
TPGESLHGYRICIQA

TMEM214

211

Q6NUQ4
TRIYHPNINSNGSIC

UBE2D3

71

P61077
PNTRHCLYGLDADLI

XRN1

196

Q8IZH2
PQVLRYHVVACHQLL

STAB2

1656

Q8WWQ8
YRCQLFIQPAGILEH

VPS13C

2586

Q709C8
YQPRIHLVRAAQLCS

TBX6

216

O95947
CHYSSVQVPRRGAIL

TTTY12

31

Q9BZ98
VNSRYSCLVAGPHQR

POLR1F

41

Q3B726
IQGLQINDYVCHPVL

RALGAPB

546

Q86X10
YRCIGLQKQQHLCSP

TAMM41

411

Q96BW9
TLRNLQPHDAGLYQC

TREM2

96

Q9NZC2
GPAVNHLYVCSICQV

USP20

771

Q9Y2K6
YLKHVCQPGRNTIQI

ZMIZ2

511

Q8NF64
GIICHFCKRNSLPQY

ZMYM2

581

Q9UBW7
CGRRFAYPSLLAIHQ

ZNF689

266

Q96CS4
LGHCELYGTNIPAVI

TTC30A

616

Q86WT1
LCAYTNPIRKGLAAH

ZNF462

1701

Q96JM2
YQGRLAVTTHGLPCL

F2

221

P00734
INHYPNGVVTVNCAR

POSTN

196

Q15063
LQAPVGSSILVQCHY

TREML1

26

Q86YW5
NYLCDSPSHVRGQQV

TLR2

561

O60603
TPYCGLRRAVQIVLH

PRSS16

326

Q9NQE7
AGVPLATLCSNLYHR

SLFN5

106

Q08AF3
LLQAYRFHACVLQLP

TERT

1006

O14746
SGALPAEHCINIYQR

TKTL1

161

P51854
LRVQHLHTPGCYQEL

TBC1D2

641

Q9BYX2
LHTPGCYQELLSRGQ

TBC1D2

646

Q9BYX2
YHFSIQGRTVCQGPL

TMEM249

121

Q2WGJ8
QGRTVCQGPLHLVYV

TMEM249

126

Q2WGJ8
CQGPLHLVYVRLALS

TMEM249

131

Q2WGJ8
GTQVCLRNNPLYHAG

UBR5

531

O95071
NIYPDGRVCISILHA

UBE2G2

81

P60604
YGIVCDASLHISNPR

VWA5B1

571

Q5TIE3
PCHAQRVLQALNAYR

KLHL35

21

Q6PF15
RGHIYLNVISSPNCD

LRIG2

776

O94898