Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprolactin receptor binding

CSH1 CSH2

1.18e-047482GO:0005148
GeneOntologyMolecularFunctiongrowth hormone receptor binding

CSH1 CSH2

2.52e-0410482GO:0005131
GeneOntologyBiologicalProcessnegative regulation of nucleobase-containing compound transport

TPR RSC1A1

1.52e-053472GO:0032240
GeneOntologyBiologicalProcesspositive regulation of developmental growth

CSH1 MAP1B CSH2 SEMA5A AKT1 HNRNPK

1.60e-05238476GO:0048639
GeneOntologyBiologicalProcessregulation of D-glucose transmembrane transport

CSH1 CSH2 AKT1 RSC1A1

9.56e-05105474GO:0010827
GeneOntologyBiologicalProcessresponse to growth hormone

CSH1 CSH2 AKT1

1.11e-0441473GO:0060416
GeneOntologyBiologicalProcesspositive regulation of growth

CSH1 MAP1B CSH2 SEMA5A AKT1 HNRNPK

1.15e-04339476GO:0045927
GeneOntologyCellularComponentgrowth hormone receptor complex

CSH1 CSH2

8.03e-056492GO:0070195
HumanPhenoCat cry

SEMA5A VPS13B

2.77e-053162HP:0200046
HumanPhenoVillous atrophy

ALG9 LRBA IL2RA

5.61e-0525163HP:0011473
HumanPhenoAbnormal small intestinal villus morphology

ALG9 LRBA IL2RA

5.61e-0525163HP:0011472
HumanPhenoAbnormal small intestinal mucosa morphology

ALG9 LRBA IL2RA

7.94e-0528163HP:0025129
DomainSOMATOTROPIN_2

CSH1 CSH2

9.24e-056472PS00338
DomainSOMATOTROPIN_1

CSH1 CSH2

9.24e-056472PS00266
DomainHormone_1

CSH1 CSH2

9.24e-056472PF00103
DomainSomatotropin

CSH1 CSH2

1.29e-047472IPR001400
Domain4_helix_cytokine_core

CSH1 CSH2

7.31e-0351472IPR012351
PathwayBIOCARTA_LONGEVITY_PATHWAY

CSH1 CSH2 AKT1

7.42e-0619293MM1513
PathwayBIOCARTA_AKT_PATHWAY

CSH1 CSH2 AKT1

1.97e-0526293MM1345
PathwayBIOCARTA_TFF_PATHWAY

CSH1 CSH2 AKT1

2.76e-0529293MM1522
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

ADAMTS12 ALG9 MUC16 SEMA5A

1.98e-04143294M27275
PathwayREACTOME_PROLACTIN_RECEPTOR_SIGNALING

CSH1 CSH2

3.14e-0413292MM14516
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

ADAMTS12 MUC16 SEMA5A

3.59e-0468293M27303
PathwayREACTOME_PEPTIDE_HORMONE_METABOLISM

CSH1 CSH2 SLC30A8

3.91e-0470293MM14916
Pubmed

Impact of obesity on the growth hormone axis: evidence for a direct inhibitory effect of hyperinsulinemia on pituitary function.

CSH1 CSH2 AKT1

3.33e-071050316513828
Pubmed

Analysis of a major human chorionic somatomammotropin gene. Evidence for two functional promoter elements.

CSH1 CSH2

2.03e-0625026208192
Pubmed

Multiple origins of transcription for the human placental lactogen genes.

CSH1 CSH2

2.03e-0625026209277
Pubmed

Identification of the interchain disulfide bonds of dimeric human placental lactogen.

CSH1 CSH2

2.03e-062502438159
Pubmed

Akt regulation of Aven contributes to the sensitivity of cancer cells to chemotherapeutic agents.

AVEN AKT1

2.03e-06250225573060
Pubmed

Amino acid sequence of human chorionic somatomammotropin.

CSH1 CSH2

2.03e-0625024712450
Pubmed

Amino-acid sequence of human placental lactogen.

CSH1 CSH2

2.03e-0625025286363
Pubmed

Two structurally different genes produce the same secreted human placental lactogen hormone.

CSH1 CSH2

2.03e-0625026300056
Pubmed

Cotranslational sequestration of egg white proteins and placental lactogen inside membrane vesicles.

CSH1 CSH2

2.03e-0625026930851
Pubmed

Construction and analysis of recombinant DNA for human chorionic somatomammotropin.

CSH1 CSH2

2.03e-062502593368
Pubmed

Interaction of hnRNP K with MAP 1B-LC1 promotes TGF-β1-mediated epithelial to mesenchymal transition in lung cancer cells.

MAP1B HNRNPK

2.03e-06250231492158
Pubmed

Premature differentiation and aberrant movement of pituitary cells lacking both Hes1 and Prop1.

CSH1 CSH2 CDH2

2.25e-061850318996108
Pubmed

A protein interaction landscape of breast cancer.

TPR AVEN SIPA1L3 AKT1 RIC8A POLR1G ZNF768 LARP7

3.19e-0663450834591612
Pubmed

Raf kinase signaling functions in sensory neuron differentiation and axon growth in vivo.

CSH1 CSH2 AKT1

4.22e-062250317396120
Pubmed

The Cockayne syndrome B protein, involved in transcription-coupled DNA repair, resides in an RNA polymerase II-containing complex.

CSH1 CSH2

6.07e-0635029312053
Pubmed

Differential placental expression profile of human Growth Hormone/Chorionic Somatomammotropin genes in pregnancies with pre-eclampsia and gestational diabetes mellitus.

CSH1 CSH2

6.07e-06350222387044
Pubmed

The human growth hormone gene locus: structure, evolution, and allelic variations.

CSH1 CSH2

6.07e-0635023030680
Pubmed

N-cadherin mediates angiogenesis by regulating monocyte chemoattractant protein-1 expression via PI3K/Akt signaling in prostate cancer cells.

AKT1 CDH2

6.07e-06350221855541
Pubmed

Late life metabolic syndrome, early growth, and common polymorphism in the growth hormone and placental lactogen gene cluster.

CSH1 CSH2

6.07e-06350215531513
Pubmed

Splicing variants of the human growth hormone mRNA: detection in pituitary, mononuclear cells and dermal fibroblasts.

CSH1 CSH2

6.07e-0635028674830
Pubmed

Phosphatase of regenerating liver 2 (PRL2) is essential for placental development by down-regulating PTEN (Phosphatase and Tensin Homologue Deleted on Chromosome 10) and activating Akt protein.

CSH1 CSH2 AKT1

6.29e-062550322791713
Pubmed

Numb deletion in POMC-expressing cells impairs pituitary intermediate lobe cell adhesion, progenitor cell localization, and neuro-intermediate lobe boundary formation.

CSH1 CSH2 CDH2

7.98e-062750321084383
Pubmed

Phospho-Akt pathway activation and inhibition depends on N-cadherin or phospho-EGFR expression in invasive human bladder cancer cell lines.

AKT1 CDH2

1.21e-05450219070520
Pubmed

Identification of functional CCAAT/enhancer-binding protein and Ets protein binding sites in the human chorionic somatomammotropin enhancer sequences.

CSH1 CSH2

1.21e-05450221737519
Pubmed

The human growth hormone gene family: nucleotide sequences show recent divergence and predict a new polypeptide hormone.

CSH1 CSH2

1.21e-0545027169009
Pubmed

Developmental control and alternative splicing of the placentally expressed transcripts from the human growth hormone gene cluster.

CSH1 CSH2

1.21e-0545021378436
Pubmed

Semaphorin 5A promotes angiogenesis by increasing endothelial cell proliferation, migration, and decreasing apoptosis.

SEMA5A AKT1

1.21e-05450219850054
Pubmed

MRE11 promotes AKT phosphorylation in direct response to DNA double-strand breaks.

AKT1 TP53BP1

1.21e-05450221623170
Pubmed

Central growth hormone action regulates metabolism during pregnancy.

CSH1 CSH2

2.02e-05550231479305
Pubmed

Molecular evolution of growth hormone and receptor in the guinea-pig, a mammal unresponsive to growth hormone.

CSH1 CSH2

2.02e-05550210767558
Pubmed

Interactions among genetic variants in apoptosis pathway genes, reflux symptoms, body mass index, and smoking indicate two distinct etiologic patterns of esophageal adenocarcinoma.

BAG6 TP53BP1

2.02e-05550220385987
Pubmed

Heterogeneous growth hormone (GH) gene mutations in familial GH deficiency.

CSH1 CSH2

2.02e-0555028496314
Pubmed

Exploring endocrine GH pattern in mice using rank plot analysis and random blood samples.

CSH1 CSH2

2.02e-05550221045135
Pubmed

Analysis of gender difference of cardiac risk biomarkers using hGH-transgenic mice.

CSH1 CSH2

2.02e-05550216508206
Pubmed

Rescue of pituitary function in a mouse model of isolated growth hormone deficiency type II by RNA interference.

CSH1 CSH2

2.02e-05550218006625
Pubmed

Growth hormone overexpression in the central nervous system results in hyperphagia-induced obesity associated with insulin resistance and dyslipidemia.

CSH1 CSH2

2.02e-05550215616010
Pubmed

Nitric oxide stimulates embryonic somatotroph differentiation and growth hormone mRNA and protein expression through a cyclic guanosine monophosphate-independent mechanism.

CSH1 CSH2

2.02e-05550219019400
Pubmed

The Effects of 20-kDa Human Placental GH in Male and Female GH-deficient Mice: An Improved Human GH?

CSH1 CSH2

2.02e-05550232556100
Pubmed

High frequency of mammary adenocarcinomas in metallothionein promoter-human growth hormone transgenic mice created from two different strains of mice.

CSH1 CSH2

2.02e-0555021525063
Pubmed

Obesity and elevated plasma leptin concentration in oMT1A-o growth hormone transgenic mice.

CSH1 CSH2

2.02e-05550211346667
Pubmed

Cardiac contractile function is enhanced in isolated ventricular myocytes from growth hormone transgenic mice.

CSH1 CSH2

2.02e-05550212010633
Pubmed

Developmentally regulated activation of a SINE B2 repeat as a domain boundary in organogenesis.

CSH1 CSH2

2.02e-05550217626886
Pubmed

Growth hormone prevents the development of autoimmune diabetes.

CSH1 CSH2

2.02e-05550224218587
Pubmed

Regulation of rapid signal transducer and activator of transcription-5 phosphorylation in the resting cells of the growth plate and in the liver by growth hormone and feeding.

CSH1 CSH2

2.02e-05550219359380
Pubmed

Body composition of inactivated growth hormone (oMt1a-oGH) transgenic mice: generation of an obese phenotype.

CSH1 CSH2

2.02e-0555029546108
Pubmed

Transgene transmission to progeny by oMt1a-oGH transgenic mice.

CSH1 CSH2

2.02e-05550216201410
Pubmed

Growth hormone stimulates the selective trafficking of thymic CD4+CD8- emigrants to peripheral lymphoid organs.

CSH1 CSH2

2.02e-05550215316240
Pubmed

Genes that prolong life: relationships of growth hormone and growth to aging and life span.

CSH1 CSH2

2.02e-05550211487592
Pubmed

Overexpressed growth hormone (GH) synergistically promotes carcinogen-initiated liver tumour growth by promoting cellular proliferation in emerging hepatocellular neoplasms in female and male GH-transgenic mice.

CSH1 CSH2

2.02e-05550211318985
Pubmed

Involvement of insulin-like growth factor-1 in the effect of caloric restriction: regulation of plasma adiponectin and leptin.

CSH1 CSH2

2.02e-05550217301034
Pubmed

Growth hormone action in the developing neural retina: a proteomic analysis.

CSH1 CSH2

2.02e-05550218203262
Pubmed

Identification of the glomerular podocyte as a target for growth hormone action.

CSH1 CSH2

2.02e-05550217272398
Pubmed

Glucose homeostasis and insulin sensitivity in growth hormone-transgenic mice: a cross-sectional analysis.

CSH1 CSH2

2.02e-05550220707609
Pubmed

Assignment of the porcine growth hormone gene to chromosome 12.

CSH1 CSH2

2.02e-0555022249485
Pubmed

Growth hormone stimulates adipogenesis of 3T3-L1 cells through activation of the Stat5A/5B-PPARgamma pathway.

CSH1 CSH2

2.02e-05550217242167
Pubmed

A single injection of double-stranded adeno-associated viral vector expressing GH normalizes growth in GH-deficient mice.

CSH1 CSH2

2.02e-05550218180319
Pubmed

Induction of mammary adenocarcinomas in metallothionein promoter-human growth hormone transgenic mice.

CSH1 CSH2

2.02e-0555021874564
Pubmed

Cloning and characterisation of the GH gene from the common dolphin (Delphinus delphis).

CSH1 CSH2

2.02e-05550212225773
Pubmed

Growth Hormone Deficiency and Excess Alter the Gut Microbiome in Adult Male Mice.

CSH1 CSH2

2.02e-05550232100023
Pubmed

The related genes encoding growth hormone and prolactin have been dispersed to chromosomes 10 and 17 in the rat.

CSH1 CSH2

2.02e-0555023780533
Pubmed

High, persistent hepatocellular proliferation and apoptosis precede hepatocarcinogenesis in growth hormone transgenic mice.

CSH1 CSH2

2.02e-05550210395045
Pubmed

Effect of genetic background on growth of mice hemizygous for wild-type or dwarf mutated bovine growth hormone transgenes.

CSH1 CSH2

2.02e-05550224190208
Pubmed

Brief report: short stature caused by a mutant growth hormone.

CSH1 CSH2

2.02e-0555028552145
Pubmed

Promotion of Joint Degeneration and Chondrocyte Metabolic Dysfunction by Excessive Growth Hormone in Mice.

CSH1 CSH2

2.02e-05550236762426
Pubmed

High molecular weight isoforms of growth hormone in cells of the immune system.

CSH1 CSH2

2.02e-05550221741628
Pubmed

Structure of the growth hormone-encoding gene and its promoter in mice.

CSH1 CSH2

2.02e-0555028647448
Pubmed

Thiol-Disulfide Exchange in Human Growth Hormone.

CSH1 CSH2

2.02e-05550226887678
Pubmed

Transgenic mice expressing bovine GH develop arthritic disorder and self-antibodies.

CSH1 CSH2

2.02e-05550210810296
Pubmed

The role of growth hormone in fetal mouse reproductive tract differentiation.

CSH1 CSH2

2.02e-0555028756530
Pubmed

GH Knockout Mice Have Increased Subcutaneous Adipose Tissue With Decreased Fibrosis and Enhanced Insulin Sensitivity.

CSH1 CSH2

2.02e-05550231099824
Pubmed

Somatotropin transgenic mice have reduced jejunal active glucose transport rates.

CSH1 CSH2

2.02e-0555027965203
Pubmed

Hot spots for growth hormone gene deletions in homologous regions outside of Alu repeats.

CSH1 CSH2

2.02e-0555021980158
Pubmed

Vitamin D3 cannot revert desensitization of growth hormone (GH)-induced STAT5-signaling in GH-overexpressing mice non-calcemic tissues.

CSH1 CSH2

2.02e-05550217881271
Pubmed

Neural growth hormone implicated in body weight sex differences.

CSH1 CSH2

2.02e-05550223861378
Pubmed

Growth hormone increases low-density lipoprotein receptor and HMG-CoA reductase mRNA expression in mesangial cells.

CSH1 CSH2

2.02e-05550212759574
Pubmed

Growth hormone production and action in N1E-115 neuroblastoma cells.

CSH1 CSH2

2.02e-05550219301152
Pubmed

Adipocyte insensitivity to insulin in growth hormone-transgenic mice.

CSH1 CSH2

2.02e-05550211350075
Pubmed

Transgenic mice overexpressing growth hormone (GH) have reduced or increased cardiac apoptosis through activation of multiple GH-dependent or -independent cell death pathways.

CSH1 CSH2

2.02e-05550218617616
Pubmed

Adipocytokines and the regulation of lipid metabolism in growth hormone transgenic and calorie-restricted mice.

CSH1 CSH2

2.02e-05550217347312
Pubmed

Growth hormone and fertility in oMt1a-oGH transgenic mice.

CSH1 CSH2

2.02e-05550211570960
Pubmed

Promoter shuffling has occurred during the evolution of the vertebrate growth hormone gene.

CSH1 CSH2

2.02e-05550210974531
Pubmed

Pleiotropic effects of growth hormone signaling in aging.

CSH1 CSH2

2.02e-05550221852148
Pubmed

Body composition, bone mass and microstructural analysis in GH-transgenic mice reveals that skeletal changes are specific to bone compartment and gender.

CSH1 CSH2

2.02e-05550212175649
Pubmed

Transgenic mice reveal novel activities of growth hormone in wound repair, angiogenesis, and myofibroblast differentiation.

CSH1 CSH2

2.02e-05550215070902
Pubmed

N-cadherin negatively regulates osteoblast proliferation and survival by antagonizing Wnt, ERK and PI3K/Akt signalling.

AKT1 CDH2

2.02e-05550220011526
Pubmed

Hepatocellular alterations and dysregulation of oncogenic pathways in the liver of transgenic mice overexpressing growth hormone.

CSH1 CSH2

2.02e-05550223428905
Pubmed

A novel missense mutation in the mouse growth hormone gene causes semidominant dwarfism, hyperghrelinemia, and obesity.

CSH1 CSH2

2.02e-05550214726450
Pubmed

UV photodegradation of murine growth hormone: chemical analysis and immunogenicity consequences.

CSH1 CSH2

2.02e-05550224758742
Pubmed

Consequences of overexpression of growth hormone in transgenic mice on liver cytochrome P450 enzymes.

CSH1 CSH2

2.02e-05550210076541
Pubmed

Overgrowth of skin in growth hormone transgenic mice depends on the presence of male gonads.

CSH1 CSH2

2.02e-05550210594738
Pubmed

Hypoxia and cytoplasmic alkalinization upregulate growth hormone expression in lymphocytes.

CSH1 CSH2

2.02e-05550223639351
Pubmed

Pituitary growth hormone network responses are sexually dimorphic and regulated by gonadal steroids in adulthood.

CSH1 CSH2

2.02e-05550221098290
Pubmed

Cardiac expression of adenine nucleotide translocase-1 in transgenic mice overexpressing bovine GH.

CSH1 CSH2

2.02e-05550217761891
Pubmed

Age-related changes in body composition of bovine growth hormone transgenic mice.

CSH1 CSH2

2.02e-05550218948397
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

TPR HECW1 MAP1B HNRNPK TP53BP1

3.00e-0525050533536335
Pubmed

The human growth hormone locus: nucleotide sequence, biology, and evolution.

CSH1 CSH2

3.03e-0565022744760
Pubmed

Growth hormone, acting in part through the insulin-like growth factor axis, rescues developmental, but not metabolic, activity in the mammary gland of mice expressing a single allele of the prolactin receptor.

CSH1 CSH2

3.03e-05650212399427
Pubmed

Transgenic mice over-expressing galanin exhibit pituitary adenomas and increased secretion of galanin, prolactin and growth hormone.

CSH1 CSH2

3.03e-05650214596666
Pubmed

GH modulates hepatic epidermal growth factor signaling in the mouse.

CSH1 CSH2

3.03e-05650220032199
Pubmed

Growth inhibition in giant growth hormone transgenic mice by overexpression of insulin-like growth factor-binding protein-2.

CSH1 CSH2

3.03e-05650211316754
Cytoband17q24.2

CSH1 CSH2

4.96e-043050217q24.2
GeneFamilyGrowth hormone family

CSH1 CSH2

5.12e-0563421175
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

SIPA1L3 UBR3 LRBA VPS13B UMAD1

2.90e-0619950594b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 SLC30A8 SEMA5A CDH2

5.05e-051815049542c19edc9bd2cba68c01c2a8407705398e3011
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 SLC30A8 SEMA5A CDH2

5.05e-051815048f04f8cac5d705dc5f6cf6f4516d6e45b0aa4ae5
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PRMT8 ZBTB4 LRBA VPS13B

5.61e-0518650477bebf576eb9b96ecb4fefb8a82a31aaaa917fc0
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PRMT8 ZBTB4 LRBA VPS13B

5.61e-0518650413bc41c60fd628af31899a5e8b480e06cc4781be
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MAP1B SLC24A2 PCDHGA6 CDH2

5.85e-05188504ed92cddf47defea2f904d36c7ae05ffa323349a9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 SLC30A8 SEMA5A CDH2

5.85e-05188504f3edcefeef2ce19086032d98b243c02a6d542b38
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 SLC30A8 SEMA5A CDH2

5.85e-051885040792432cd4c564dea1102241ea9884f7ced7658c
ToppCellP07-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADAMTS12 MAP1B SEMA5A CDH2

5.85e-051885046ec22b79b19d57ea187f312907819dc2d01f3efe
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1B SLC24A2 SLC30A8 RNF182

6.22e-05191504f76f3f5c7902a3659d8cbe470f96ce57c8a6744d
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1B SLC24A2 SLC30A8 CDH2

6.35e-051925041304e69c92cef3bd8c82e3c035a7562f5440139a
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTS12 MAP1B SEMA5A CDH2

6.48e-0519350488916d9a7d831eb52848599917c04238f8f9812b
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1B SLC24A2 SLC30A8 CDH2

6.61e-0519450492b39a935e8c577eb1123d706d168fa13cf3344c
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1B SLC24A2 SLC30A8 CDH2

6.74e-051955043e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1B SLC24A2 SLC30A8 CDH2

6.74e-051955047796ea9247f4c63762f0de8490fed08b9717fa23
Diseaseisolated growth hormone deficiency type II (implicated_via_orthology)

CSH1 CSH2

2.69e-055492DOID:0060872 (implicated_via_orthology)
Diseaseisolated growth hormone deficiency (implicated_via_orthology)

CSH1 CSH2

5.64e-057492DOID:0060870 (implicated_via_orthology)
Diseaset-tau measurement

ADAMTS12 MAP1B IL2RA UMAD1

5.79e-05126494EFO_0004760
DiseaseMalignant neoplasm of breast

AKT1 RIC8A LRBA CDH2 VPS13B RNF182 HNRNPK TP53BP1 DOP1A

6.00e-051074499C0006142
Diseaseuveitis

TNRC18 POLR1G

9.65e-059492EFO_1001231
DiseaseMammary Carcinoma, Human

AKT1 RIC8A CDH2 RNF182 HNRNPK TP53BP1

2.25e-04525496C4704874
DiseaseMammary Neoplasms, Human

AKT1 RIC8A CDH2 RNF182 HNRNPK TP53BP1

2.25e-04525496C1257931
DiseaseMammary Neoplasms

AKT1 RIC8A CDH2 RNF182 HNRNPK TP53BP1

2.30e-04527496C1458155
Diseasecongenital hypothyroidism (biomarker_via_orthology)

CSH1 CSH2

2.43e-0414492DOID:0050328 (biomarker_via_orthology)
DiseaseBreast Carcinoma

AKT1 RIC8A CDH2 RNF182 HNRNPK TP53BP1

2.57e-04538496C0678222
Disease3-hydroxy-1-methylpropylmercapturic acid measurement

KIAA1210 HECW1 SEMA5A BEND2 VCX

2.91e-04352495EFO_0007015
Diseaseiritis

TNRC18 POLR1G

3.62e-0417492EFO_1000997
Diseaseosteoporosis (biomarker_via_orthology)

CSH1 CSH2

6.11e-0422492DOID:11476 (biomarker_via_orthology)
Diseaseidiopathic pulmonary fibrosis (is_marker_for)

AKT1 IL2RA

6.68e-0423492DOID:0050156 (is_marker_for)
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement

SLC30A8 SEMA5A

1.07e-0329492EFO_0004735, EFO_0004736
DiseaseCleft palate, cleft lip

MAP1B CHM POLR1G VPS13B

1.19e-03279494EFO_0003959, HP_0000175
Diseaseresponse to aromatase inhibitor

MUC16 SEMA5A

1.30e-0332492GO_0061477
Diseaseovarian neoplasm

MUC16 AKT1 TP53BP1

1.45e-03134493C0919267
DiseaseMalignant neoplasm of ovary

MUC16 AKT1 TP53BP1

1.54e-03137493C1140680
Diseasechronic kidney disease, diabetic nephropathy

SLC24A2 SLC30A8

1.64e-0336492EFO_0000401, EFO_0003884
Diseasecataract (implicated_via_orthology)

SIPA1L3 VPS13B

1.83e-0338492DOID:83 (implicated_via_orthology)
Diseasetype 2 diabetes mellitus (biomarker_via_orthology)

CSH1 CSH2 AKT1

1.89e-03147493DOID:9352 (biomarker_via_orthology)
Diseasetype 1 diabetes mellitus (implicated_via_orthology)

CSH1 CSH2

1.92e-0339492DOID:9744 (implicated_via_orthology)
DiseaseNon-Small Cell Lung Carcinoma

AVEN AKT1 TP53BP1

2.23e-03156493C0007131
Diseaseasthma, chronic obstructive pulmonary disease

IL2RA CDH2

3.15e-0350492EFO_0000341, MONDO_0004979

Protein segments in the cluster

PeptideGeneStartEntry
ENSSSVTVSDPEMEN

UMAD1

56

C9J7I0
EFTAQMITITPPDQD

AKT1

441

P31749
MEPNDSTSTAVEEPD

BAG6

1

P46379
IVPTDMNDQNLEEPS

ALG9

511

Q9H6U8
VDPETVNAQEDSQMP

DOP1A

1126

Q5JWR5
MAENAAESTEVNSPP

PRMT8

16

Q9NR22
IQTMVSDEQALPPTD

ADAMTS12

911

P58397
MSENVPIAEDTTEQP

CHM

196

P24386
NPDSVSNTPEMEQRE

NVL

131

O15381
PMESNPSIVLADETN

NPAT

351

Q14207
MSQEEPPELTSSQTI

MUC16

3086

Q8WXI7
QDTFTMDPSNTTPQA

MUC16

4986

Q8WXI7
PSPDQSTMSQDISTE

MUC16

9046

Q8WXI7
ENMNSQPEKTVTTPT

OGFRL1

401

Q5TC84
TVLDVNDNTPMFTQP

PCDHGA6

231

Q9Y5G7
QSTIEISSEPTPMDE

MAP1B

1121

P46821
STEPESAQIQDSPMN

HECW1

356

Q76N89
TEMPGTTETNVENNS

BEND2

351

Q8NDZ0
SDSIPTPSNMEETQQ

CSH2

81

P0DML3
TEPEIQQEMSTSQPD

MPHOSPH9

21

Q99550
PTVDSVSQDPVSNMS

LRBA

1781

P50851
SESEMETDSGVPQNT

LARP7

411

Q4G0J3
EQMVDTPASEPAQAS

P2RX2

446

Q9UBL9
VTEEKNMEPEQPSTS

AVEN

331

Q9NQS1
NMEPEQPSTSKNVTE

AVEN

336

Q9NQS1
TTEMQSPMQPVDQAS

IL2RA

106

P01589
KDNMEQPTTSQPETT

KIAA1210

591

Q9ULL0
SDSIPTPSNMEETQQ

CSH1

81

P0DML2
QSPAMPMQNSSEEIT

RSC1A1

91

Q92681
QTVSDKNMPDSENPT

S100PBP

221

Q96BU1
TVTDVNDNPPEFTAM

CDH2

371

P19022
STQNVDSEMMSNPPV

RTL9

376

Q8NET4
DVEMTPSSDASEPVQ

SLC24A2

421

Q9UI40
METEQPEETFPNTET

HNRNPK

1

P61978
QSQESRMPETVPQEE

POLR1G

466

O15446
MNTSEPKTEQESITP

SIPA1L3

1056

O60292
MASQPPEDTAESQAS

RNF182

1

Q8N6D2
QQNTRDPDTMVPLTD

STARD9

1071

Q9P2P6
VDPEVVNMDTTAPSQ

NPAP1

571

Q9NZP6
ETMEQQLSSDPDSDP

RIC8A

516

Q9NPQ8
VQPVTTVPSFMEDNS

SEMA5A

386

Q13591
QVAPSESQPTLEMSD

TNRC18

1281

O15417
SLTIQMESPVDQDPD

SLC30A8

346

Q8IWU4
TQTEPEGSQPSTMDA

ZNF653

366

Q96CK0
TQVESQEAMQSEGPV

TPR

1721

P12270
EPQDVQSSDEMRSPE

ZNF768

11

Q9H5H4
EEAPQEMQVSSSSGE

ZBTB4

816

Q9P1Z0
ENTQIEDTEPMSPVL

TP53BP1

541

Q12888
TTQPNSMESNEEEPV

TRAV26-2

21

A0A0B4J265
QESQVEEPPSQESEM

VCX

186

Q9H320
EDVSSPPQRSSETMQ

SLC7A6

26

Q92536
NDIPMEITTAEPQVS

UBR3

1216

Q6ZT12
NFEVQVSEPVPQMSS

VPS13B

2271

Q7Z7G8