Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC6A18 SLC6A4 MCOLN1 CNGA1 SLC6A14

2.54e-05171415GO:0015081
GeneOntologyMolecularFunctionMHC protein complex binding

LILRB5 HLA-DRB4 HLA-DRB5

8.11e-0541413GO:0023023
GeneOntologyMolecularFunctionG protein-coupled acetylcholine receptor activity

CHRM1 CHRM4

8.58e-057412GO:0016907
GeneOntologyMolecularFunctionprotein-glutamine gamma-glutamyltransferase activity

TGM1 TGM3

1.47e-049412GO:0003810
GeneOntologyMolecularFunctionCD4 receptor binding

CD22 HLA-DRB5

2.24e-0411412GO:0042609
GeneOntologyMolecularFunctionIgM binding

CD22 LILRB5

2.24e-0411412GO:0001791
GeneOntologyMolecularFunctionprostanoid receptor activity

TBXA2R PTGER2

2.68e-0412412GO:0004954
GeneOntologyMolecularFunctionG protein-coupled neurotransmitter receptor activity

CHRM1 CHRM4

3.16e-0413412GO:0099528
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC6A18 SLC6A4 CACNG6 MCOLN1 CNGA1 SLC6A14

3.48e-04465416GO:0046873
GeneOntologyMolecularFunctioncarbohydrate binding

SIGLEC14 CRYBG1 CHIA CD22 HLA-DRB5

4.14e-04310415GO:0030246
GeneOntologyMolecularFunctionicosanoid receptor activity

TBXA2R PTGER2

4.85e-0416412GO:0004953
GeneOntologyMolecularFunctionsodium:chloride symporter activity

SLC6A18 SLC6A4

5.49e-0417412GO:0015378
GeneOntologyMolecularFunctionserine-type endopeptidase activity

C2 PRSS2 CELA2B CELA2A

6.11e-04190414GO:0004252
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC6A18 SLC6A4 SLC6A14

6.13e-0481413GO:0015370
GeneOntologyMolecularFunctionmonoatomic anion:sodium symporter activity

SLC6A18 SLC6A4

6.88e-0419412GO:0015373
GeneOntologyMolecularFunctionserine-type peptidase activity

C2 PRSS2 CELA2B CELA2A

8.41e-04207414GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

C2 PRSS2 CELA2B CELA2A

9.19e-04212414GO:0017171
GeneOntologyMolecularFunctionG protein-coupled serotonin receptor activity

CHRM1 CHRM4

9.26e-0422412GO:0004993
GeneOntologyMolecularFunctionacetylcholine receptor activity

CHRM1 CHRM4

1.01e-0323412GO:0015464
GeneOntologyMolecularFunctionchloride:monoatomic cation symporter activity

SLC6A18 SLC6A4

1.01e-0323412GO:0015377
GeneOntologyMolecularFunctionamino acid:sodium symporter activity

SLC6A18 SLC6A14

1.01e-0323412GO:0005283
GeneOntologyMolecularFunctionsialic acid binding

SIGLEC14 CD22

1.20e-0325412GO:0033691
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

TBXA2R PLCD4 MYCBP2 CHRM4

1.26e-03231414GO:0005085
GeneOntologyMolecularFunctionphosphatidylinositol phospholipase C activity

PLCD4 CHRM1

1.30e-0326412GO:0004435
GeneOntologyMolecularFunctionmonoatomic anion:monoatomic cation symporter activity

SLC6A18 SLC6A4

1.30e-0326412GO:0015296
GeneOntologyMolecularFunctionMHC class II protein complex binding

HLA-DRB4 HLA-DRB5

1.40e-0327412GO:0023026
GeneOntologyMolecularFunctionamino acid:monoatomic cation symporter activity

SLC6A18 SLC6A14

1.61e-0329412GO:0005416
GeneOntologyMolecularFunctionphospholipase C activity

PLCD4 CHRM1

1.61e-0329412GO:0004629
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC6A18 SLC6A4 CACNG6 MCOLN1 CNGA1 SLC6A14

1.65e-03627416GO:0022890
GeneOntologyMolecularFunctionendopeptidase activity

C2 PRSS2 MME CELA2B CELA2A

1.79e-03430415GO:0004175
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC6A18 SLC6A4 SLC6A14

1.87e-03119413GO:0015294
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

MCOLN1 CNGA1

2.09e-0333412GO:0005217
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC6A18 SLC6A4 CACNG6 MCOLN1 CNGA1 SLC6A14

2.20e-03664416GO:0008324
GeneOntologyMolecularFunctioncalcium channel activity

CACNG6 MCOLN1 CNGA1

2.35e-03129413GO:0005262
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC6A18 SLC6A4 CACNG6 MCOLN1 ABCA13 CNGA1 ABCA7 SLC6A14

2.42e-031180418GO:0022857
GeneOntologyMolecularFunctionimmunoglobulin binding

CD22 LILRB5

2.48e-0336412GO:0019865
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC6A18 SLC6A4 ABCA13 ABCA7 SLC6A14

2.81e-03477415GO:0022804
GeneOntologyMolecularFunctionG protein-coupled amine receptor activity

CHRM1 CHRM4

3.21e-0341412GO:0008227
GeneOntologyMolecularFunctionneutral L-amino acid transmembrane transporter activity

SLC6A18 SLC6A14

3.21e-0341412GO:0015175
GeneOntologyMolecularFunctionsymporter activity

SLC6A18 SLC6A4 SLC6A14

3.59e-03150413GO:0015293
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC6A18 SLC6A4 MCOLN1

3.66e-03151413GO:0008509
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNG6 MCOLN1 CNGA1

3.66e-03151413GO:0015085
GeneOntologyMolecularFunctionpeptide binding

MME LILRB5 HLA-DRB4 HLA-DRB5

4.02e-03318414GO:0042277
GeneOntologyMolecularFunctiontransporter activity

SLC6A18 SLC6A4 CACNG6 MCOLN1 ABCA13 CNGA1 ABCA7 SLC6A14

4.17e-031289418GO:0005215
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC6A18 SLC6A4 CACNG6 MCOLN1 CNGA1 SLC6A14

4.24e-03758416GO:0015318
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA13 ABCA7

4.55e-0349412GO:0140359
GeneOntologyMolecularFunctionpeptide antigen binding

HLA-DRB4 HLA-DRB5

4.55e-0349412GO:0042605
GeneOntologyMolecularFunctionsodium channel activity

MCOLN1 CNGA1

5.11e-0352412GO:0005272
GeneOntologyMolecularFunctionmonoatomic cation channel activity

SLC6A4 CACNG6 MCOLN1 CNGA1

5.25e-03343414GO:0005261
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC6A18 SLC6A4 CACNG6 MCOLN1 CNGA1 SLC6A14

5.28e-03793416GO:0015075
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

TBXA2R TNFRSF25 PTGER2 CHRM1 ABCA7 CHRM4 LILRB5 HLA-DRB5

5.58e-031353418GO:0004888
GeneOntologyMolecularFunctioncoreceptor activity

CD22 LILRB5

9.60e-0372412GO:0015026
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

CHRM1 CHRM4

1.04e-0275412GO:0098960
GeneOntologyMolecularFunctionpeptidase activity

C2 PRSS2 MME CELA2B CELA2A

1.05e-02654415GO:0008233
GeneOntologyMolecularFunctioncarboxylic acid binding

SIGLEC14 DMBT1 CD22

1.29e-02239413GO:0031406
GeneOntologyMolecularFunctioncargo receptor activity

DMBT1 ABCA7

1.32e-0285412GO:0038024
GeneOntologyMolecularFunctionmonoatomic ion channel activity

SLC6A4 CACNG6 MCOLN1 CNGA1

1.43e-02459414GO:0005216
GeneOntologyMolecularFunctionorganic acid binding

SIGLEC14 DMBT1 CD22

1.52e-02254413GO:0043177
GeneOntologyMolecularFunctionphosphoric diester hydrolase activity

PLCD4 CHRM1

1.69e-0297412GO:0008081
GeneOntologyBiologicalProcesspeptide cross-linking

TGM1 TGM3 ABCA7

2.06e-0527413GO:0018149
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SLC6A18 SLC6A4 MCOLN1 CNGA1 SLC6A14

5.54e-05208415GO:0035725
GeneOntologyBiologicalProcessconditioned place preference

SLC6A4 CSMD1

5.75e-056412GO:1990708
GeneOntologyBiologicalProcesspositive regulation of apoptotic cell clearance

C2 ABCA7

1.07e-048412GO:2000427
GeneOntologyBiologicalProcessamyloid-beta clearance by cellular catabolic process

MME ABCA7

1.07e-048412GO:0150094
GeneOntologyBiologicalProcessadenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway

CHRM1 CHRM4

1.07e-048412GO:0007197
GeneOntologyBiologicalProcessregulation of apoptotic cell clearance

C2 ABCA7

1.72e-0410412GO:2000425
GeneOntologyBiologicalProcesscognition

SLC6A4 MME CSMD1 CHRM1 ABCA7 LILRB5

1.76e-04423416GO:0050890
GeneOntologyBiologicalProcesssodium ion transport

SLC6A18 SLC6A4 MCOLN1 CNGA1 SLC6A14

2.06e-04275415GO:0006814
GeneOntologyBiologicalProcessMHC class II protein complex assembly

HLA-DRB4 HLA-DRB5

4.55e-0416412GO:0002399
GeneOntologyBiologicalProcesspeptide antigen assembly with MHC class II protein complex

HLA-DRB4 HLA-DRB5

4.55e-0416412GO:0002503
GeneOntologyCellularComponentkeratohyalin granule

CELA2B CELA2A

3.93e-055422GO:0036457
GeneOntologyCellularComponentcytoplasmic vesicle membrane

SLC6A4 SIGLEC14 MME DMBT1 DCSTAMP MCOLN1 ABCA13 ABCA7 HLA-DRB4 HLA-DRB5

2.06e-0413074210GO:0030659
GeneOntologyCellularComponentvesicle membrane

SLC6A4 SIGLEC14 MME DMBT1 DCSTAMP MCOLN1 ABCA13 ABCA7 HLA-DRB4 HLA-DRB5

2.30e-0413254210GO:0012506
GeneOntologyCellularComponentMHC class II protein complex

HLA-DRB4 HLA-DRB5

5.26e-0417422GO:0042613
GeneOntologyCellularComponentendocytic vesicle membrane

DMBT1 MCOLN1 HLA-DRB4 HLA-DRB5

8.51e-04212424GO:0030666
GeneOntologyCellularComponentneuron projection terminus

MME CHRM1 CNGA1 CHRM4

1.21e-03233424GO:0044306
GeneOntologyCellularComponentendosome membrane

SLC6A4 DCSTAMP MCOLN1 ABCA7 HLA-DRB4 HLA-DRB5

1.21e-03602426GO:0010008
GeneOntologyCellularComponentMHC protein complex

HLA-DRB4 HLA-DRB5

1.24e-0326422GO:0042611
GeneOntologyCellularComponentphagocytic cup

MCOLN1 ABCA7

1.77e-0331422GO:0001891
GeneOntologyCellularComponentendosome

SLC6A4 MME DCSTAMP CD22 MCOLN1 ABCA7 HLA-DRB4 HLA-DRB5

1.99e-031167428GO:0005768
GeneOntologyCellularComponentlumenal side of endoplasmic reticulum membrane

HLA-DRB4 HLA-DRB5

2.25e-0335422GO:0098553
GeneOntologyCellularComponentbrush border

SLC6A18 MME SLC6A14

3.52e-03152423GO:0005903
GeneOntologyCellularComponentcollagen-containing extracellular matrix

TGM3 PRSS2 CELA2B DMBT1 CELA2A

4.03e-03530425GO:0062023
GeneOntologyCellularComponentlumenal side of membrane

HLA-DRB4 HLA-DRB5

4.19e-0348422GO:0098576
GeneOntologyCellularComponentsecretory granule membrane

SIGLEC14 MME DMBT1 ABCA13

4.21e-03329424GO:0030667
GeneOntologyCellularComponentlysosome

SIGLEC14 PRSS2 MCOLN1 ABCA13 HLA-DRB4 HLA-DRB5

5.33e-03811426GO:0005764
GeneOntologyCellularComponentlytic vacuole

SIGLEC14 PRSS2 MCOLN1 ABCA13 HLA-DRB4 HLA-DRB5

5.33e-03811426GO:0000323
GeneOntologyCellularComponentlate endosome membrane

MCOLN1 HLA-DRB4 HLA-DRB5

5.55e-03179423GO:0031902
DomainNA_NEUROTRAN_SYMP_2

SLC6A18 SLC6A4 SLC6A14

7.26e-0618403PS00754
DomainNA_NEUROTRAN_SYMP_3

SLC6A18 SLC6A4 SLC6A14

8.61e-0619403PS50267
DomainSNF

SLC6A18 SLC6A4 SLC6A14

8.61e-0619403PF00209
DomainNa/ntran_symport

SLC6A18 SLC6A4 SLC6A14

8.61e-0619403IPR000175
DomainNA_NEUROTRAN_SYMP_1

SLC6A18 SLC6A4 SLC6A14

8.61e-0619403PS00610
DomainTRYPSIN_SER

C2 PRSS2 CELA2B CELA2A

4.04e-0590404IPR033116
DomainThbox_rcpt

TBXA2R PTGER2

4.45e-055402IPR001105
DomainMusac_Ach_rcpt

CHRM1 CHRM4

4.45e-055402IPR000995
Domain-

SIGLEC14 TGM1 TGM3 CD22 MYCBP2 LILRB5 HLA-DRB4 HLA-DRB5

6.79e-056634082.60.40.10
DomainTRYPSIN_HIS

C2 PRSS2 CELA2B CELA2A

6.84e-05103404IPR018114
DomainTRYPSIN_SER

C2 PRSS2 CELA2B CELA2A

7.65e-05106404PS00135
DomainTRYPSIN_HIS

C2 PRSS2 CELA2B CELA2A

7.94e-05107404PS00134
DomainPeptidase_S1A

C2 PRSS2 CELA2B CELA2A

9.81e-05113404IPR001314
DomainTRYPSIN_DOM

C2 PRSS2 CELA2B CELA2A

1.05e-04115404PS50240
DomainIg-like_fold

SIGLEC14 TGM1 TGM3 CD22 MYCBP2 LILRB5 HLA-DRB4 HLA-DRB5

1.05e-04706408IPR013783
DomainTryp_SPc

C2 PRSS2 CELA2B CELA2A

1.12e-04117404SM00020
DomainProstanoid_rcpt

TBXA2R PTGER2

1.24e-048402IPR008365
DomainMHC_II_b_N

HLA-DRB4 HLA-DRB5

1.24e-048402PD000328
DomainTrypsin

C2 PRSS2 CELA2B CELA2A

1.28e-04121404PF00089
DomainTrypsin_dom

C2 PRSS2 CELA2B CELA2A

1.28e-04121404IPR001254
DomainPeptidase_S1_PA

C2 PRSS2 CELA2B CELA2A

1.36e-04123404IPR009003
DomainTransglut_N

TGM1 TGM3

1.59e-049402PF00868
DomainTRANSGLUTAMINASES

TGM1 TGM3

1.59e-049402PS00547
DomainTransglutaminase_N

TGM1 TGM3

1.59e-049402IPR001102
DomainMHC_II_beta

HLA-DRB4 HLA-DRB5

1.59e-049402PF00969
DomainMHC_II_b_N

HLA-DRB4 HLA-DRB5

1.59e-049402IPR000353
DomainTransglut_C

TGM1 TGM3

1.59e-049402PF00927
Domain-

TGM1 TGM3

1.59e-0494023.90.260.10
DomainGln_gamma-glutamylTfrase_euk

TGM1 TGM3

1.59e-049402IPR023608
DomainTransglutaminase_AS

TGM1 TGM3

1.59e-049402IPR013808
DomainMHC_II_beta

HLA-DRB4 HLA-DRB5

1.59e-049402SM00921
DomainTransglutaminase_C

TGM1 TGM3

1.99e-0410402IPR008958
DomainTGc

TGM1 TGM3

2.43e-0411402SM00460
DomainTransglut_core

TGM1 TGM3

2.43e-0411402PF01841
DomainTransglutaminase-like

TGM1 TGM3

2.43e-0411402IPR002931
DomainIg/MHC_CS

SIGLEC14 HLA-DRB4 HLA-DRB5

2.59e-0458403IPR003006
DomainIG_MHC

SIGLEC14 HLA-DRB4 HLA-DRB5

2.86e-0460403PS00290
DomainABC_A

ABCA13 ABCA7

2.91e-0412402IPR026082
DomainMHC_II_a/b_N

HLA-DRB4 HLA-DRB5

4.00e-0414402IPR014745
Domain-

HLA-DRB4 HLA-DRB5

4.00e-04144023.10.320.10
DomainIg_2

SIGLEC14 CD22 LILRB5

5.10e-0473403PF13895
DomainIg_E-set

TGM1 TGM3 MYCBP2

1.43e-03104403IPR014756
DomainMHC_I/II-like_Ag-recog

HLA-DRB4 HLA-DRB5

2.99e-0338402IPR011162
DomainIG_LIKE

SIGLEC14 CD22 LILRB5 HLA-DRB4 HLA-DRB5

3.79e-03491405PS50835
DomainIg-like_dom

SIGLEC14 CD22 LILRB5 HLA-DRB4 HLA-DRB5

4.20e-03503405IPR007110
DomainABC_TRANSPORTER_2

ABCA13 ABCA7

4.74e-0348402PS50893
DomainABC_tran

ABCA13 ABCA7

4.74e-0348402PF00005
DomainABC_TRANSPORTER_1

ABCA13 ABCA7

4.94e-0349402PS00211
DomainCUB

DMBT1 CSMD1

4.94e-0349402PF00431
DomainCUB

DMBT1 CSMD1

5.13e-0350402SM00042
DomainABC_transporter-like

ABCA13 ABCA7

5.13e-0350402IPR003439
DomainSushi

C2 CSMD1

5.54e-0352402PF00084
Domain-

DMBT1 CSMD1

5.54e-03524022.60.120.290
DomainCUB

DMBT1 CSMD1

5.75e-0353402PS01180
DomainC1-set

HLA-DRB4 HLA-DRB5

5.97e-0354402PF07654
DomainCCP

C2 CSMD1

5.97e-0354402SM00032
DomainSUSHI

C2 CSMD1

6.40e-0356402PS50923
DomainIGc1

HLA-DRB4 HLA-DRB5

6.40e-0356402SM00407
DomainSushi_SCR_CCP_dom

C2 CSMD1

6.63e-0357402IPR000436
DomainCUB_dom

DMBT1 CSMD1

6.63e-0357402IPR000859
DomainIg_C1-set

HLA-DRB4 HLA-DRB5

6.85e-0358402IPR003597
Domainig

SIGLEC14 CD22 LILRB5

7.77e-03190403PF00047
DomainImmunoglobulin

SIGLEC14 CD22 LILRB5

7.77e-03190403IPR013151
PathwayREACTOME_MUSCARINIC_ACETYLCHOLINE_RECEPTORS

CHRM1 CHRM4

5.96e-055352M27300
PathwayREACTOME_MUSCARINIC_ACETYLCHOLINE_RECEPTORS

CHRM1 CHRM4

5.96e-055352MM15006
PathwayKEGG_HEMATOPOIETIC_CELL_LINEAGE

MME CD22 HLA-DRB4 HLA-DRB5

6.12e-0587354M6856
PathwayBIOCARTA_PEPI_PATHWAY

CELA2B CELA2A

1.25e-047352MM1589
PathwayBIOCARTA_PEPI_PATHWAY

CELA2B CELA2A

1.66e-048352M22084
PathwayREACTOME_PROSTANOID_LIGAND_RECEPTORS

TBXA2R PTGER2

2.13e-049352M804
PathwayREACTOME_PROSTANOID_LIGAND_RECEPTORS

TBXA2R PTGER2

2.13e-049352MM15014
PathwayBIOCARTA_BBCELL_PATHWAY

HLA-DRB4 HLA-DRB5

3.25e-0411352M22030
PathwayBIOCARTA_EOSINOPHILS_PATHWAY

HLA-DRB4 HLA-DRB5

3.25e-0411352M22048
PathwayBIOCARTA_IL5_PATHWAY

HLA-DRB4 HLA-DRB5

4.59e-0413352M18928
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

TBXA2R PRSS2 PTGER2 CHRM1 CHRM4

5.21e-04272355M13380
PathwayBIOCARTA_MHC_PATHWAY

HLA-DRB4 HLA-DRB5

5.35e-0414352M22023
PathwayBIOCARTA_BLYMPHOCYTE_PATHWAY

HLA-DRB4 HLA-DRB5

5.35e-0414352M1473
PathwayBIOCARTA_TCRA_PATHWAY

HLA-DRB4 HLA-DRB5

5.35e-0414352M10765
PathwayREACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS

TBXA2R PTGER2

5.35e-0414352MM15012
PathwayREACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS

TBXA2R PTGER2

6.16e-0415352M10620
PathwayKEGG_MEDICUS_REFERENCE_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_II_MOLECULES

HLA-DRB4 HLA-DRB5

6.16e-0415352M47604
PathwayBIOCARTA_ASBCELL_PATHWAY

HLA-DRB4 HLA-DRB5

6.16e-0415352M7298
PathwayKEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_NFY_MEDIATED_TRANSCRIPTION

HLA-DRB4 HLA-DRB5

6.16e-0415352M47588
PathwayWP_GPCRS_SMALL_LIGAND

TBXA2R PTGER2

8.94e-0418352MM15858
PathwayREACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS

SLC6A18 SLC6A14

9.97e-0419352MM15107
PathwayWP_SMALL_LIGAND_GPCRS

TBXA2R PTGER2

9.97e-0419352M39728
PathwayREACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS

SLC6A18 SLC6A14

9.97e-0419352M27362
PathwayBIOCARTA_EICOSANOID_PATHWAY

TBXA2R PTGER2

1.11e-0320352MM1529
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

TBXA2R PTGER2 CHRM1 CHRM4

1.12e-03186354MM15994
PathwayREACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

TGM1 CELA2B CELA2A

1.29e-0387353MM15351
PathwayBIOCARTA_CTLA4_PATHWAY

HLA-DRB4 HLA-DRB5

1.34e-0322352M1467
PathwayBIOCARTA_EICOSANOID_PATHWAY

TBXA2R PTGER2

1.34e-0322352M22003
PathwayBIOCARTA_CSK_PATHWAY

HLA-DRB4 HLA-DRB5

1.34e-0322352M6327
PathwayBIOCARTA_TH1TH2_PATHWAY

HLA-DRB4 HLA-DRB5

1.47e-0323352M6705
PathwayREACTOME_PD_1_SIGNALING

HLA-DRB4 HLA-DRB5

2.17e-0328352M18810
PathwayBIOCARTA_INFLAM_PATHWAY

HLA-DRB4 HLA-DRB5

2.33e-0329352M6910
PathwayKEGG_ASTHMA

HLA-DRB4 HLA-DRB5

2.49e-0330352M13950
PathwayWP_MONOAMINE_GPCRS

CHRM1 CHRM4

2.66e-0331352MM15871
PathwayREACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE

SLC6A18 SLC6A14

2.83e-0332352MM14957
PathwayWP_MONOAMINE_GPCRS

CHRM1 CHRM4

3.01e-0333352M39585
PathwayREACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE

SLC6A18 SLC6A14

3.01e-0333352M188
PathwayKEGG_ALLOGRAFT_REJECTION

HLA-DRB4 HLA-DRB5

3.78e-0337352M18615
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

TBXA2R PTGER2 CHRM1 CHRM4

3.78e-03260354M39397
PathwayWP_GPCRS_NONODORANT

TBXA2R PTGER2 CHRM1 CHRM4

4.10e-03266354MM15843
PathwayREACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES

HLA-DRB4 HLA-DRB5

4.19e-0339352M16523
PathwayKEGG_CELL_ADHESION_MOLECULES_CAMS

CD22 HLA-DRB4 HLA-DRB5

4.31e-03133353M16476
PathwayKEGG_GRAFT_VERSUS_HOST_DISEASE

HLA-DRB4 HLA-DRB5

4.62e-0341352M13519
PathwayREACTOME_AMINE_LIGAND_BINDING_RECEPTORS

CHRM1 CHRM4

4.84e-0342352M5868
PathwayREACTOME_AMINE_LIGAND_BINDING_RECEPTORS

CHRM1 CHRM4

4.84e-0342352MM14971
PathwayKEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS

C2 HLA-DRB4 HLA-DRB5

4.88e-03139353M4741
PathwayWP_NRF2_PATHWAY

SLC6A18 SLC6A4 SLC6A14

5.07e-03141353M39454
PathwayKEGG_TYPE_I_DIABETES_MELLITUS

HLA-DRB4 HLA-DRB5

5.07e-0343352M12617
PathwayKEGG_ABC_TRANSPORTERS

ABCA13 ABCA7

5.31e-0344352M11911
PathwayWP_PROSTAGLANDIN_SYNTHESIS_AND_REGULATION

TBXA2R PTGER2

5.54e-0345352M39355
PathwayKEGG_INTESTINAL_IMMUNE_NETWORK_FOR_IGA_PRODUCTION

HLA-DRB4 HLA-DRB5

6.29e-0348352M615
PathwayREACTOME_KERATINIZATION

TGM1 CELA2B CELA2A

6.36e-03153353MM15343
PathwayKEGG_MEDICUS_REFERENCE_GPCR_PLCB_ITPR_SIGNALING_PATHWAY

TBXA2R CHRM1

6.81e-0350352M47951
PathwayKEGG_AUTOIMMUNE_THYROID_DISEASE

HLA-DRB4 HLA-DRB5

7.35e-0352352M13103
Pubmed

Sequence organisation and transcriptional regulation of the mouse elastase II and trypsin genes.

PRSS2 CELA2B CELA2A

5.71e-0874233641189
Pubmed

Sequence analysis of three novel DRw14-DRB1 alleles.

HLA-DRB4 HLA-DRB5

1.42e-0624221612646
Pubmed

Differential expression of transglutaminase genes in patients with chronic periodontitis.

TGM1 TGM3

1.42e-06242224112124
Pubmed

Elastase-2, a Tissue Alternative Pathway for Angiotensin II Generation, Plays a Role in Circulatory Sympathovagal Balance in Mice.

CELA2B CELA2A

1.42e-06242228386233
Pubmed

Crystal structures of the M1 and M4 muscarinic acetylcholine receptors.

CHRM1 CHRM4

1.42e-06242226958838
Pubmed

Inactivity of recombinant ELA2B provides a new example of evolutionary elastase silencing in humans.

CELA2B CELA2A

1.42e-06242216327289
Pubmed

Ectopic transglutaminase 1 and 3 expression accelerating keratinization in oral lichen planus.

TGM1 TGM3

1.42e-06242230213231
Pubmed

Muscarinic Receptors Expression in the Peripheral Blood Cells Differentiate Dementia with Lewy Bodies from Alzheimer's Disease.

CHRM1 CHRM4

1.42e-06242234806612
Pubmed

Identification of two novel HLA-DRB1 alleles, DRB1*0903 and DRB1*1145.

HLA-DRB4 HLA-DRB5

1.42e-06242215191532
Pubmed

Structural basis for the coordinated regulation of transglutaminase 3 by guanine nucleotides and calcium/magnesium.

TGM1 TGM3

1.42e-06242214645372
Pubmed

Detection of four novel alleles: DRB1*1130, DRB1*13072, DRB1*1315 and DRB1*1331.

HLA-DRB4 HLA-DRB5

1.42e-06242210703621
Pubmed

Investigation of mouse amniotic fluid for stimulating ability of keratinocyte differentiation depending on the fetal stage.

TGM1 TGM3

1.42e-06242234390735
Pubmed

Characterization of pancreatic elastase II cDNAs: two elastase II mRNAs are expressed in human pancreas.

CELA2B CELA2A

1.42e-0624223646943
Pubmed

Characterization of three HLA-DR beta genes isolated from an HLA-DR 3/4 insulin-dependent diabetic patient.

HLA-DRB4 HLA-DRB5

1.42e-0624223015788
Pubmed

Decreased muscarinic1 receptors in the dorsolateral prefrontal cortex of subjects with schizophrenia.

CHRM1 CHRM4

1.42e-06242212476323
Pubmed

Two DR2-associated novel alleles arose from the silent mutation of codon 72: DRB1*16012, DRB5*01012.

HLA-DRB4 HLA-DRB5

1.42e-06242210551425
Pubmed

The repertoire of solute carriers of family 6: identification of new human and rodent genes.

SLC6A18 SLC6A4 SLC6A14

2.15e-062142316125675
Pubmed

Complete cDNA sequences of the HLA-DRB1*0402 and DRB1*11041 alleles.

HLA-DRB4 HLA-DRB5

4.27e-06342212358860
Pubmed

SPINK5 and Netherton syndrome: novel mutations, demonstration of missing LEKTI, and differential expression of transglutaminases.

TGM1 TGM3

4.27e-06342215304086
Pubmed

Mhc-DRB diversity of the chimpanzee (Pan troglodytes).

HLA-DRB4 HLA-DRB5

4.27e-0634221428007
Pubmed

Direct sequencing of SSP-PCR-amplified cDNA to identify new alleles in the DR52-associated DRB1 group: identification of DRB1*1115, DRB1*1117 and DRB1*1319.

HLA-DRB4 HLA-DRB5

4.27e-0634227652736
Pubmed

Prostaglandin E2 deficiency causes a phenotype of aspirin sensitivity that depends on platelets and cysteinyl leukotrienes.

TBXA2R PTGER2

4.27e-06342224085850
Pubmed

Assignment of muscarinic receptor subtypes mediating G-protein modulation of Ca(2+) channels by using knockout mice.

CHRM1 CHRM4

4.27e-06342210485923
Pubmed

Allelic diversity is generated by intraexon sequence exchange at the DRB1 locus of primates.

HLA-DRB4 HLA-DRB5

4.27e-0634222023919
Pubmed

Effects of muscarinic receptor antagonists on cocaine discrimination in wild-type mice and in muscarinic receptor M1, M2, and M4 receptor knockout mice.

CHRM1 CHRM4

4.27e-06342228442355
Pubmed

Genetic variation in the epidermal transglutaminase genes is not associated with atopic dermatitis.

TGM1 TGM3

4.27e-06342223189155
Pubmed

Recent origin of HLA-DRB1 alleles and implications for human evolution.

HLA-DRB4 HLA-DRB5

4.27e-0634229500545
Pubmed

A novel DRB1*09 allelic sequence in the Jing ethnic minority of China.

HLA-DRB4 HLA-DRB5

4.27e-06342212121280
Pubmed

HLA-DR allele frequencies in Mexican mestizos with autoimmune liver diseases including overlap syndromes.

HLA-DRB4 HLA-DRB5

4.27e-06342219811438
Pubmed

Diversity associated with the second expressed HLA-DRB locus in the human population.

HLA-DRB4 HLA-DRB5

4.27e-0634229162096
Pubmed

Polymorphism of human Ia antigens generated by reciprocal intergenic exchange between two DR beta loci.

HLA-DRB4 HLA-DRB5

4.27e-0634223099214
Pubmed

Gene disruption of tissue transglutaminase.

TGM1 TGM3

4.27e-06342211113189
Pubmed

Hornerin is a component of the epidermal cornified cell envelopes.

TGM1 TGM3

4.27e-06342221282207
Pubmed

No gender differences in the frequencies of HLA-DRB3/B4/B5 heterozygotes in newborns and adults in Koreans.

HLA-DRB4 HLA-DRB5

4.27e-06342222531795
Pubmed

A novel HLA-DRB1*09 allele, HLA-DRB1*090103*, isolated from the Han population of Guangdong, China.

HLA-DRB4 HLA-DRB5

4.27e-06342215730527
Pubmed

Primary structure of human pancreatic elastase 2 determined by sequence analysis of the cloned mRNA.

CELA2B CELA2A

4.27e-0634223427074
Pubmed

[Association of hemorrhagic fever with renal syndrome and HLA-DRB allele polymorphisms in Han nationality, Hubei province].

HLA-DRB4 HLA-DRB5

4.27e-06342220193583
Pubmed

Shared class II MHC polymorphisms between humans and chimpanzees.

HLA-DRB4 HLA-DRB5

4.27e-0634222511168
Pubmed

Thromboxane A2 induces blood flow recovery via platelet adhesion to ischaemic regions.

TBXA2R PTGER2

4.27e-06342225935870
Pubmed

Intact coupling of M1 receptors and preserved M2 and M4 receptors in the cortex in progressive supranuclear palsy: contrast with other dementias.

CHRM1 CHRM4

4.27e-06342218282687
Pubmed

Mutant huntingtin protein: a substrate for transglutaminase 1, 2, and 3.

TGM1 TGM3

4.27e-06342215715085
Pubmed

Low prevalence of IgA anti-transglutaminase 1, 2, and 3 autoantibodies in children with atopic dermatitis.

TGM1 TGM3

4.27e-06342224885370
Pubmed

Expression of Transglutaminase in Foreskin of Children with Balanitis Xerotica Obliterans.

TGM1 TGM3

4.27e-06342227649154
Pubmed

Identification of a novel HLA-DRB1*09 allele, DRB1*0904, in the Korean population, by sequence-based typing.

HLA-DRB4 HLA-DRB5

4.27e-06342216441501
Pubmed

Distinct endocytic mechanisms of CD22 (Siglec-2) and Siglec-F reflect roles in cell signaling and innate immunity.

SIGLEC14 CD22

8.53e-06442217562860
Pubmed

Allelic variation in the DR subregion of the human major histocompatibility complex.

HLA-DRB4 HLA-DRB5

8.53e-0644223476943
Pubmed

TGM1/3-mediated transamidation of Exo70 promotes tumor metastasis upon LKB1 inactivation.

TGM1 TGM3

8.53e-06442239146185
Pubmed

Next-Generation Sequencing Reveals That HLA-DRB3, -DRB4, and -DRB5 May Be Associated With Islet Autoantibodies and Risk for Childhood Type 1 Diabetes.

HLA-DRB4 HLA-DRB5

8.53e-06442226740600
Pubmed

Identification and characterization of muscarinic acetylcholine receptor subtypes expressed in human skin melanocytes.

CHRM1 CHRM4

8.53e-06442211855742
Pubmed

Muscarinic receptor subtypes. Physiology and clinical implications.

CHRM1 CHRM4

8.53e-0644222674717
Pubmed

Acetylcholine analogue stimulates DNA synthesis in brain-derived cells via specific muscarinic receptor subtypes.

CHRM1 CHRM4

8.53e-0644222739737
Pubmed

Blockade of M4 muscarinic receptors on striatal cholinergic interneurons normalizes striatal dopamine release in a mouse model of TOR1A dystonia.

CHRM1 CHRM4

8.53e-06442235314320
Pubmed

Muscarinic acetylcholine receptors activate expression of the EGR gene family of transcription factors.

CHRM1 CHRM4

8.53e-0644229603968
Pubmed

Identification of a family of muscarinic acetylcholine receptor genes.

CHRM1 CHRM4

8.53e-0644223037705
Pubmed

Two distinct classes of muscarinic action on hippocampal inhibitory synapses: M2-mediated direct suppression and M1/M3-mediated indirect suppression through endocannabinoid signalling.

CHRM1 CHRM4

8.53e-06442215147302
Pubmed

Analysis of DR beta and DQ beta chain cDNA clones from a DR7 haplotype.

HLA-DRB4 HLA-DRB5

8.53e-0644223020127
Pubmed

Ciliary activity in the oviduct of cycling, pregnant, and muscarinic receptor knockout mice.

CHRM1 CHRM4

8.53e-06442222302687
Pubmed

HLA-DRB alleles and systemic lupus erythematosus in Jamaicans.

HLA-DRB4 HLA-DRB5

8.53e-06442212144077
Pubmed

Transglutaminase and clusterin induction during normal and abnormal limb development in the mouse.

TGM1 TGM3

8.53e-0644228828830
Pubmed

Associations of human leukocyte antigen DRB with resistance or susceptibility to HIV-1 infection in the Pumwani Sex Worker Cohort.

HLA-DRB4 HLA-DRB5

8.53e-06442218520346
Pubmed

Two divergent routes of evolution gave rise to the DRw13 haplotypes.

HLA-DRB4 HLA-DRB5

8.53e-0644222212675
Pubmed

Lack of 'tissue' transglutaminase protein cross-linking leads to leakage of macromolecules from dying cells: relationship to development of autoimmunity in MRLIpr/Ipr mice.

TGM1 TGM3

8.53e-06442216465267
Pubmed

Regulated expression of tissue transglutaminase in Swiss 3T3 fibroblasts: effects on the processing of fibronectin, cell attachment, and cell death.

TGM1 TGM3

8.53e-0644229511731
Pubmed

Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors.

CHRM1 CHRM4

8.53e-0644223443095
Pubmed

M(1)/M(3) and M(2)/M(4) muscarinic receptor double-knockout mice present distinct respiratory phenotypes.

CHRM1 CHRM4

8.53e-06442218206430
Pubmed

Dynamic control of glutamatergic synaptic input in the spinal cord by muscarinic receptor subtypes defined using knockout mice.

CHRM1 CHRM4

1.42e-05542220940295
Pubmed

Cooperation between mast cells and neurons is essential for antigen-mediated bronchoconstriction.

SLC6A4 CHRM1

1.42e-05542219494266
Pubmed

Muscarinic acetylcholine receptor subtype 4 is essential for cholinergic stimulation of duodenal bicarbonate secretion in mice - relationship to D cell/somatostatin.

CHRM1 CHRM4

1.42e-05542226084221
Pubmed

Acetylcholine modulates cortical synaptic transmission via different muscarinic receptors, as studied with receptor knockout mice.

CHRM1 CHRM4

1.42e-05542215919709
Pubmed

Use of M1-M5 muscarinic receptor knockout mice as novel tools to delineate the physiological roles of the muscarinic cholinergic system.

CHRM1 CHRM4

1.42e-05542212675128
Pubmed

Regulation of CD8+ cytolytic T lymphocyte differentiation by a cholinergic pathway.

CHRM1 CHRM4

1.42e-05542215913791
Pubmed

Muscarinic acetylcholine receptor subtypes: localization and structure/function.

CHRM1 CHRM4

1.42e-0554228248499
Pubmed

NY-ESO-1 119-143 is a promiscuous major histocompatibility complex class II T-helper epitope recognized by Th1- and Th2-type tumor-reactive CD4+ T cells.

HLA-DRB4 HLA-DRB5

1.42e-05542211782380
Pubmed

Antinuclear antibodies and HLA class II alleles in Jamaican patients with systemic lupus erythematosus.

HLA-DRB4 HLA-DRB5

1.42e-05542217910142
Pubmed

The M1 muscarinic acetylcholine receptor subtype is important for retinal neuron survival in aging mice.

CHRM1 CHRM4

1.42e-05542230914695
Pubmed

Quantitative analysis of binding parameters of [3H]N-methylscopolamine in central nervous system of muscarinic acetylcholine receptor knockout mice.

CHRM1 CHRM4

1.42e-05542215661360
Pubmed

Major histocompatibility complex class II molecules promote human immunodeficiency virus type 1 assembly and budding to late endosomal/multivesicular body compartments.

HLA-DRB4 HLA-DRB5

1.42e-05542216973583
Pubmed

Microglia activation in Niemann-Pick disease, type C1 is amendable to therapeutic intervention.

CD22 MCOLN1

1.42e-05542229617956
Pubmed

Genetic variability in HIV-1 gp120 affects interactions with HLA molecules and T cell receptor.

HLA-DRB4 HLA-DRB5

1.42e-0554221970352
Pubmed

Cross-reactive cytotoxic T lymphocytes induced by V3 loop synthetic peptides from different strains of human immunodeficiency virus type 1.

HLA-DRB4 HLA-DRB5

1.42e-0554227645219
Pubmed

Antipsychotic-like Effects of M4 Positive Allosteric Modulators Are Mediated by CB2 Receptor-Dependent Inhibition of Dopamine Release.

CHRM1 CHRM4

1.42e-05542227618677
Pubmed

A comparison of HLA-DR and -DQ allele and haplotype frequencies in Trinidadian populations of African, South Asian, and mixed ancestry.

HLA-DRB4 HLA-DRB5

1.42e-05542212392858
Pubmed

Differential regulation of primary afferent input to spinal cord by muscarinic receptor subtypes delineated using knockout mice.

CHRM1 CHRM4

1.42e-05542224695732
Pubmed

Muscarinic receptors in the prenatal mouse embryo. Comparison of M35-immunohistochemistry with [3H]quinuclidinyl benzylate autoradiography.

CHRM1 CHRM4

1.42e-0554227648406
Pubmed

Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1 (keratinocyte transglutaminase).

TGM1 TGM3

1.42e-0554229448282
Pubmed

Roles of M2 and M4 muscarinic receptors in regulating acetylcholine release from myenteric neurons of mouse ileum.

CHRM1 CHRM4

1.42e-05542215574798
Pubmed

HLA-DQ8 and the HLA-DQ8-DR4 haplotype are positively associated with the hevein-specific IgE immune response in health care workers with latex allergy.

HLA-DRB4 HLA-DRB5

1.42e-05542212209103
Pubmed

Association of Brain DNA methylation in SORL1, ABCA7, HLA-DRB5, SLC24A4, and BIN1 with pathological diagnosis of Alzheimer disease.

ABCA7 HLA-DRB5

1.42e-05542225365775
Pubmed

Expansion of monocytic myeloid-derived suppressor cells dampens T cell function in HIV-1-seropositive individuals.

HLA-DRB4 HLA-DRB5

1.42e-05542223152536
Pubmed

HLA-DR-restricted peptides identified in the Nef protein can induce HIV type 1-specific IL-2/IFN-gamma-secreting CD4+ and CD4+ /CD8+ T cells in humans after lipopeptide vaccination.

HLA-DRB4 HLA-DRB5

1.42e-05542217411376
Pubmed

Expression of multiple subtypes of muscarinic receptors and cellular distribution in the human heart.

CHRM1 CHRM4

1.42e-05542211306684
Pubmed

Productive human immunodeficiency virus type 1 assembly takes place at the plasma membrane.

HLA-DRB4 HLA-DRB5

1.42e-05542217507489
Pubmed

Signaling through the M(3) muscarinic receptor favors bone mass accrual by decreasing sympathetic activity.

CHRM1 CHRM4

1.42e-05542220197056
Pubmed

Competition of HLA-DR and a beta 2 domain peptide for HIV envelope glycoprotein gp120 binding to CD4.

HLA-DRB4 HLA-DRB5

1.42e-0554227734415
Pubmed

Multiple muscarinic acetylcholine receptor subtypes modulate striatal dopamine release, as studied with M1-M5 muscarinic receptor knock-out mice.

CHRM1 CHRM4

1.42e-05542212151512
Pubmed

Muscarinic receptors 2 and 5 regulate bitter response of urethral brush cells via negative feedback.

CHRM1 CHRM4

1.42e-05542229401598
Pubmed

Muscarinic receptor subtypes in cilia-driven transport and airway epithelial development.

CHRM1 CHRM4

1.42e-05542219213795
Pubmed

The role of muscarinic receptor subtypes in acetylcholine release from urinary bladder obtained from muscarinic receptor knockout mouse.

CHRM1 CHRM4

1.42e-05542218755247
Pubmed

Visual hallucinations and HLA class II antigens in cortical dementia.

HLA-DRB4 HLA-DRB5

1.42e-05542220606439
Pubmed

Elastase 2 is expressed in human and mouse epidermis and impairs skin barrier function in Netherton syndrome through filaggrin and lipid misprocessing.

CELA2B CELA2A

1.42e-05542220179351
Cytoband19q13.4

SIGLEC14 CACNG6 LILRB5

5.36e-057942319q13.4
Cytoband1p36.21

CELA2B CELA2A

1.54e-03634221p36.21
Cytoband6p21.3

C2 HLA-DRB4 HLA-DRB5

1.57e-032504236p21.3
GeneFamilyCholinergic receptors muscarinic

CHRM1 CHRM4

2.84e-055312180
GeneFamilyTransglutaminases

TGM1 TGM3

1.02e-049312773
GeneFamilyProstaglandin (prostanoid) receptors

TBXA2R PTGER2

1.02e-049312207
GeneFamilyATP binding cassette subfamily A

ABCA13 ABCA7

2.56e-0414312805
GeneFamilyCD molecules|C2-set domain containing|Sialic acid binding Ig like lectins

SIGLEC14 CD22

1.05e-0328312745
GeneFamilyC1-set domain containing

HLA-DRB4 HLA-DRB5

2.35e-0342312591
GeneFamilyHistocompatibility complex|C1-set domain containing

HLA-DRB4 HLA-DRB5

2.57e-0344312588
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

C2 CSMD1

4.28e-03573121179
CoexpressionNABA_MATRISOME_HYPERPLASTIC_PANCREATIC_ISLETS

PRSS2 CELA2B DMBT1 CELA2A

6.78e-0826404MM17051
CoexpressionVILIMAS_NOTCH1_TARGETS_DN

CELA2B LILRB5 CELA2A

1.91e-0534403MM791
CoexpressionBERGER_MBD2_TARGETS

PRSS2 CELA2A

2.26e-055402M2296
CoexpressionNABA_ECM_REGULATORS

TGM1 TGM3 PRSS2 CELA2B CELA2A

3.00e-05238405M3468
CoexpressionNABA_ECM_REGULATORS

TGM1 TGM3 PRSS2 CELA2B CELA2A

3.25e-05242405MM17062
CoexpressionHE_LIM_SUN_FETAL_LUNG_C2_SPP1_POS_MACROPHAGE_CELL

C2 TNFRSF25 LILRB5

5.43e-0548403M45740
CoexpressionTABULA_MURIS_SENIS_PANCREAS_LEUKOCYTE_AGEING

PRSS2 CELA2B CELA2A

6.14e-0550403MM3814
CoexpressionFOSTER_KDM1A_TARGETS_UP

CRYBG1 CELA2B DCSTAMP HLA-DRB5 CELA2A

1.17e-04317405MM956
CoexpressionBERGER_MBD2_TARGETS

CELA2B CELA2A

1.24e-0411402MM905
CoexpressionAtlaslung

SLC6A4 C2 CHIA DCSTAMP SLC6A14 HLA-DRB5

9.42e-07182396lung
ToppCell390C-Myeloid-Macrophage|390C / Donor, Lineage, Cell class and subclass (all cells)

MME CELA2B MCOLN1 LILRB5 HLA-DRB5

8.44e-07190415f933d971f092c4e56e9f670a9205b688c8b1ca28
ToppCell390C-Myeloid-Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

C2 MME MCOLN1 LILRB5 HLA-DRB5

9.59e-07195415ba494be431916d43c1d480f65bed674c0722c710
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

C2 MME CELA2B MCOLN1 HLA-DRB5

9.84e-07196415eb7d6bbfb766cdeaf5fe0f0bb66a5f491fd5ef26
ToppCellSerous|World / shred by cell class for turbinate

DMBT1 CHRM1 CNGA1 PGBD3

1.09e-051504146a326662d58b0f17d6efa8cc28571f4cbbf57c2d
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGM3 PRSS2 CHIA CELA2A

1.12e-05151414a306e8dac653bc785d805d8d2d94feec3cb01727
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TGM3 DMBT1 ABCA13 CNGA1

1.48e-05162414bf886e22ff2a20353499004b53f25fb9e6574896
ToppCelltumor_Lung-T/NK_cells-Cytotoxic_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

CERCAM CACNG6 PTGER2 HLA-DRB5

1.55e-0516441460fe6bb86afaebd92590135f08f5434ce0d8d73c
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD4_INF-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CRYBG1 TNFRSF25 TDRD9 PTGER2

1.63e-05166414000faacc79b0bd279ddce4e692d801e7e2063ab6
ToppCelldroplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGM1 PRSS2 DMBT1 CELA2A

1.63e-05166414b7f303203068b205f382788815df487a0ea148ed
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS2 PTGER2 MCOLN1 CELA2A

2.00e-051754143bca1aac2a2a1f46753b5f9462888f144ed8327b
ToppCellBronchial_Biopsy-Immune-Luminal_Macrophages|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

SIGLEC14 MME CELA2B DCSTAMP

2.00e-051754141cf99de391552d4f8dbe2ed5b01fc3b8adca61b6
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS2 TDRD9 MYCBP2 CELA2A

2.05e-05176414feafc757e7aa4f17128ff34886beb2fd3461c9ea
ToppCellfacs-Heart-LA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS2 CHIA CD22 CELA2A

2.05e-05176414077f3fe5e3482ea3f639d789bd3d584161b36c02
ToppCell3'_v3-GI_small-bowel-Myeloid_Mac-Macrophage|GI_small-bowel / Manually curated celltypes from each tissue

SIGLEC14 C2 MME DCSTAMP

2.05e-051764144be270f6bb7da4070f972aca403109751646d155
ToppCellfacs-Heart-LA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS2 CHIA CD22 CELA2A

2.05e-05176414fc2ba468677b19b55130c1f06737f40300cd9d2e
ToppCellwk_15-18-Hematologic-Myeloid-APOE+_Mac2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

C2 MCOLN1 LILRB5 HLA-DRB5

2.24e-05180414c630a121aedd09a51ea18cc6e8552eb979e5b555
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Alveolar_Mac|Myeloid_cells / Location, Cell class and cell subclass

C2 MME DCSTAMP HLA-DRB5

2.33e-05182414a035d45fd512bee8dac38eb387dbf39f5a8a1fed
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS2 MME DMBT1 CELA2A

2.59e-051874149aa411ae9b5a923378a5daebb8bb2fc2613f2510
ToppCellFetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TNFRSF25 MCOLN1 LILRB5 HLA-DRB5

2.59e-0518741439b99f46b723f7f3c44880d7fe8642cbad558b8a
ToppCell368C-Myeloid-Macrophage|368C / Donor, Lineage, Cell class and subclass (all cells)

C2 MME MCOLN1 HLA-DRB5

2.71e-05189414e62355be0d136e2b7c739848022292e9c6af7392
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.0.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SIGLEC14 C2 MCOLN1 HLA-DRB5

2.71e-051894146cdd743bc46e34dc48288dda343309131b6c2d5f
ToppCell3'_v3-lymph-node_spleen-Myeloid_Mac|lymph-node_spleen / Manually curated celltypes from each tissue

C2 MME DCSTAMP LILRB5

2.71e-05189414aac79c41ce7acba722c45c016b2c6997fb772a96
ToppCell3'_v3-lymph-node_spleen-Myeloid_Mac-Erythrophagocytic_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

C2 DCSTAMP MCOLN1 LILRB5

2.76e-0519041496c6078619e85f630c9754aca5d6066433e22836
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_2|356C / Donor, Lineage, Cell class and subclass (all cells)

MME CELA2B DCSTAMP MCOLN1

2.76e-051904144cce4ddb79b7751d0103e10f71156977e0c34439
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

C2 CNGA1 LILRB5 HLA-DRB5

2.88e-05192414935a4a36881a9fa4daa02cba96af07f6686ed8d6
ToppCell3'-Child04-06-SmallIntestine-Epithelial-Tuft-related|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SH2D6 DMBT1 CSMD1 ABCA13

2.88e-05192414d6ea34391c3f730684b82e912d9cf55e928b3311
ToppCell390C-Myeloid-Macrophage-FABP4+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

C2 MME CELA2B MCOLN1

2.94e-05193414c9cf5a661294a947d06d53d18d47362c0e0b6ef5
ToppCellfacs-Pancreas-Exocrine-3m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS2 MME DMBT1 CELA2A

2.94e-05193414c3161a14a40323a58aa202c8a1d6ea0e9c2b9814
ToppCellmyeloid-macrophage|World / Lineage and Cell class

C2 MCOLN1 LILRB5 HLA-DRB5

2.94e-05193414b13e694123b87ed8ad1786feb996398ddd84e94b
ToppCell356C-Myeloid-Macrophage|356C / Donor, Lineage, Cell class and subclass (all cells)

MME DCSTAMP MCOLN1 HLA-DRB5

3.00e-051944143844e6fb43ae2e0a35ea8ccc1a2e11f40b68bc67
ToppCell343B-Myeloid-Macrophage|343B / Donor, Lineage, Cell class and subclass (all cells)

MME DCSTAMP MCOLN1 HLA-DRB5

3.06e-0519541448ba2044d2459c8b0d17bc7deca8d0195ac6a00e
ToppCell(7)_Epithelial-A_(AT2)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

C2 CHIA DMBT1 SLC6A14

3.06e-05195414c9a6c65ee18d83bf34a4713d306a6e30db1325c2
ToppCell(7)_MNP-(7)_Macrophage|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)

C2 CD22 MCOLN1 LILRB5

3.12e-0519641471ec157163278ad259c190051926bf41e4ecef46
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

C2 DCSTAMP MCOLN1 LILRB5

3.12e-05196414bd2c2de103e28b65ea537c22f71225cb0deef1e0
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

C2 MME CELA2B HLA-DRB5

3.12e-05196414173d2c38a01c9ae1c50657d5fc383238aed4aacb
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

C2 DCSTAMP MCOLN1 LILRB5

3.12e-05196414072a4150ae521c6589b0f7cd60e975fb33715bf4
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

C2 MME CELA2B HLA-DRB5

3.12e-051964142793ad692d49b3ee78a5cd2d8e0220bf5188a686
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

C2 MME CELA2B HLA-DRB5

3.12e-05196414aae79eafe5bc2c7de16958994a2fe97439d7bea1
ToppCell(7)_Macrophage|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

C2 MCOLN1 LILRB5 HLA-DRB5

3.12e-05196414f1c822860d2a0bae84b0263b0151185756423e0f
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SIGLEC14 C2 LILRB5 HLA-DRB5

3.18e-0519741467bf15ee83938bd40f6ecd5abaaf90ad95096d21
ToppCell343B-Myeloid-Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

C2 MME MCOLN1 HLA-DRB5

3.18e-051974141b6f7a62b7fcfd55c25c5840353eed7183050860
ToppCellBronchus_Control_(B.)-Immune-TX-TRAM-2|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

C2 MME CELA2B LILRB5

3.18e-05197414eecb693367510da20a6b1e9355e68785a1e3b85c
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Htr1a_(Neuron.Slc17a6.Htr1a)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

TGM3 DCSTAMP SLC6A14

3.23e-0567413be6853b5bf254063f02a4c478fd4c3fef68cb77a
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Htr1a_(Neuron.Slc17a6.Htr1a)|Hippocampus / BrainAtlas - Mouse McCarroll V32

TGM3 DCSTAMP SLC6A14

3.23e-05674137483b85423d9d07b01b60927d0fe1b7ccb241d7f
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MME DCSTAMP LILRB5 HLA-DRB5

3.31e-0519941498c0d57c247d39bc771d81f4387f8dd01222628e
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_alveolar|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

C2 DMBT1 ABCA7 SLC6A14

3.31e-051994147ebd89dff457f57a549eecee288c7a4b515b4018
ToppCell10x5'v1-week_17-19-Myeloid_macrophage|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

C2 DCSTAMP MCOLN1 LILRB5

3.31e-05199414980b10b81ee9dc952e3be25bd294201ce5a4ca8b
ToppCell10x5'-Liver-Myeloid_Mac-Erythrophagocytic_macrophages|Liver / Manually curated celltypes from each tissue

C2 MCOLN1 LILRB5 HLA-DRB5

3.31e-05199414600afac424416268766fc5c051d4c62ab9eef5de
ToppCell10x5'v1-week_17-19-Myeloid_macrophage-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

C2 DCSTAMP MCOLN1 LILRB5

3.31e-05199414cbd423c31d75f6d2f5ae85d2241641fcbe630b81
ToppCellASK454-Immune-B_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

C2 DMBT1 SLC6A14 HLA-DRB5

3.31e-05199414cbfabf8e895abe454606b990f99e3738f4263ffe
ToppCellwk_15-18-Hematologic-Myeloid-SPP1+_Mac|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

C2 MCOLN1 LILRB5 HLA-DRB5

3.31e-05199414c7fc2ac1601346aac71e7620a8a440fde8d92dbd
ToppCell10x5'-Liver-Myeloid_Mac|Liver / Manually curated celltypes from each tissue

C2 MCOLN1 LILRB5 HLA-DRB5

3.31e-05199414aed138ee879e4e625f177c5bfe0f857a335eb6f2
ToppCellBiopsy_IPF-Epithelial-AT2|Biopsy_IPF / Sample group, Lineage and Cell type

C2 CHIA DMBT1 SLC6A14

3.31e-05199414c841d475703d3489161fb7904526bd7563d5fb0f
ToppCellParenchymal-10x5prime-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MME DCSTAMP MCOLN1 HLA-DRB5

3.37e-05200414980cb0390586d8312890e8d0f3cf58e3309d16c5
ToppCell10x5'-Lung-Myeloid_Mac-Alveolar_macrophages|Lung / Manually curated celltypes from each tissue

C2 MME MCOLN1 HLA-DRB5

3.37e-052004143b236900df407bf5a8c44e76d003a7a37d251db6
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

C2 CHIA DMBT1 SLC6A14

3.37e-0520041465c83a3f6ee2a10bcb5b95076696232c6373a7b4
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

C2 CHIA DMBT1 SLC6A14

3.37e-0520041440e969883bc302e8fbc6b6ab9814529dc1472902
ToppCellParenchyma_Control_(B.)-Epithelial-TX-AT2-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

C2 CHIA DMBT1 SLC6A14

3.37e-05200414ad9cdc82a647d379abc713a56db0e11bb6494106
ToppCellParenchymal-10x5prime-Immune_Myeloid-Macrophage_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MME DCSTAMP MCOLN1 HLA-DRB5

3.37e-05200414d7d971586c01152b3d21956fd98280588cb8f08b
ToppCelldroplet-Pancreas-Exocrine-18m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS2 DMBT1 CELA2A

3.69e-057041326178ee967d647224d93c7a6380f2d15d8fcfb8f
ToppCelldroplet-Pancreas-Exocrine-24m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS2 DMBT1 CELA2A

3.69e-05704135720505ef03d65c73028616c808420e282823bde
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS2 DMBT1 CELA2A

9.76e-059741316947da747504c2edb9f2e7ee6f05babda0fae60
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS2 DMBT1 CELA2A

1.27e-041064133aa55c3db4e4abd39c8f2f89f2516927d94ad9d7
ToppCelldroplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS2 DMBT1 CELA2A

1.27e-04106413c890c838785dfeda30f3b563194da9cfb49b157a
ToppCellTCGA-Testes-Primary_Tumor-Testicular_Germ_Cell_Tumor-Testicular_Germ_Cell_Tumor-4|TCGA-Testes / Sample_Type by Project: Shred V9

CHIA DMBT1 SLC6A14

1.49e-041124133ec029eac64247c5e48074dad5c71df690e84f4c
ToppCelldroplet-Skin-nan-18m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGM1 TGM3 CHRM1

2.32e-041304134c8b931987432e8bcd39029d4fa124dc383ea355
ToppCelldroplet-Pancreas-Exocrine-21m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS2 DMBT1 CELA2A

2.48e-0413341391e4556658e49f92946d48b194df64c5fc5758fe
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A4 CHIA DMBT1

2.53e-0413441345c0cccca133ffc261ba45271d72b21f5402ec3c
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Alveolar_Mac|Myeloid_cells / Location, Cell class and cell subclass

MME CELA2B DCSTAMP

2.94e-04141413399380de5ea09e22fd128e3e55fffeffc4874c15
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MME ABCA13 LILRB5

3.01e-04142413191a13bba143ecdfc2bfd797c3ac191481388298
ToppCellCOVID-19_Mild-Myeloid_G|COVID-19_Mild / Disease group, lineage and cell class

CACNG6 MME ABCA13

3.01e-04142413c8aeb747ed836197265d269aa131fae172b45aec
ToppCellmild_COVID-19-B_cell|World / disease group, cell group and cell class (v2)

MME CD22 HLA-DRB5

3.07e-041434134698cc877dda9b1ef7d6f18c9adc869ef791b1d8
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

C2 DCSTAMP HLA-DRB5

3.07e-041434134c5a5db46beb8f2f3c40e8ed95911fbfea61bae0
ToppCellPBMC-Mild-Myeloid-Neutrophil|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

CACNG6 MME ABCA13

3.07e-04143413974260c25dad599eea83a33e83117f7307b92a42
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MME ABCA13 LILRB5

3.07e-04143413b405dba9a83a99cc7b53ce71772bc52a0bbb0d4e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS2 CHIA CELA2A

3.33e-041474139bc4185920b2b0f1fd5c6e2ec5583b9cd49c2efd
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A4 CRYBG1 CNGA1

3.33e-0414741364fa0753a3a79f492ef8acc6942bf90d379a983f
ToppCellBronchus_Control_(B.)-Immune-TX-TRAM-3|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

SH2D6 CD22 HLA-DRB5

3.33e-0414741350a855aa7f214c3be8ac46a22adf9bc9dd0285db
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS2 CHIA CELA2A

3.33e-041474139b0f87a6dd5224c2b06deafeae04a1b04e53eb75
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNFRSF25 CELA2B FAM120C

3.53e-0415041353de595376a9fc92491dfd58ff25938b0bf79903
ToppCellTCGA-Lung|World / Sample_Type by Project: Shred V9

CHIA ABCA13 SLC6A14

3.53e-041504138c133206786e8f22bb70f2a7de9c0cb7f9ea9313
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNFRSF25 CELA2B FAM120C

3.53e-04150413e4b40b3243ed26d0c46bf196ac06e148834e7ed2
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

TGM1 MME CELA2B

3.67e-041524137a1072315cce71eefe2d32149a107d5648999968
ToppCellfacs-Brain_Myeloid-Cortex-3m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C2 TGM3 PTGER2

3.74e-041534130ef7c45cdd854c79e527006034029767f8e108b2
ToppCelldroplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS2 DMBT1 CELA2A

3.74e-0415341339ac25c48e73538f1c10f37bea386e0e88d3e8d0
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS2 CHIA CELA2A

3.81e-04154413c6f1a0806d492b1f01cded2daffaf3f13422deb6
ToppCellE16.5-samps-Epithelial-Alveolar_epithelial_precursor-Noncycling_AT1_Precursor|E16.5-samps / Age Group, Lineage, Cell class and subclass

TGM1 TNFRSF25 SLC6A14

3.81e-041544138a643d91896af9b630a715fb284c1523d01ad1a3
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS2 CHIA CELA2A

3.81e-04154413665885d8aca168513ab7a65f70d52181c821eb78
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS2 CHIA CELA2A

3.81e-041544133c64111e2ca1bb04ddd1ecb19938a307778ff7eb
ToppCellAT1-AT2_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

SLC6A4 DMBT1 SLC6A14

3.88e-04155413010e45ef4b505bf419ea41e4d1619521d1c78319
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Alveolar_Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

MME CELA2B DCSTAMP

3.88e-0415541303fd443740272dcb547e39deaf7ae89b8307f241
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_2|367C / Donor, Lineage, Cell class and subclass (all cells)

MME CELA2B CELA2A

3.96e-041564131a0e081284a99c1b345990775015b8a2fa469496
ToppCellfacs-Skin-Telogen-3m-Epithelial-inner_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXA2R CHIA CD22

3.96e-04156413ba9dfee9373d657d2a55572b41fc62001ad8b037
ToppCellfacs-MAT-Fat-24m|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS2 CHIA CELA2A

3.96e-041564137433c6d4eb4d061844d8979c1e648d8ed56e1073
ToppCellSmart-seq2-thymus_(Smart-seq2)-lymphocytic-B_lymphocytic-memory_B_cell|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DCSTAMP MYCBP2 CELA2A

3.96e-04156413cea7b4f133272499e77ed451db91f699cff6a4bb
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNFRSF25 FAM120C HLA-DRB5

3.96e-04156413a5930b455e5c8586c43c50106ab4d8a1e5e9e3d6
ToppCellfacs-MAT-Fat-24m-Epithelial-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS2 CHIA CELA2A

4.03e-0415741330814ff90cead688ef64dac4cf4a6d63756d8944
ToppCellfacs-MAT-Fat-24m-Epithelial|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS2 CHIA CELA2A

4.03e-04157413a47d102570e82d34ea1a8756f82636e7ab27c07f
ToppCellfacs-MAT-Fat-24m-Epithelial-epithelial_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS2 CHIA CELA2A

4.03e-041574137c20f225b2db8b340f4fec050ff29e666b860f04
ToppCellfacs-Lung-3m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TDRD9 CNGA1 CHRM4

4.18e-041594134750ba9ca06ed97b18df3c74eeb51d3ac8763f63
ComputationalSerine proteases.

C2 PRSS2 CELA2B CELA2A

2.09e-0639264MODULE_109
ComputationalNeighborhood of SERPINI2

PRSS2 CELA2B CELA2A

2.79e-0525263GNF2_SERPINI2
ComputationalGenes in the cancer module 293.

HLA-DRB4 HLA-DRB5

3.66e-0412262MODULE_293
ComputationalGenes in the cancer module 143.

HLA-DRB4 HLA-DRB5

5.03e-0414262MODULE_143
DrugParoxetine

SLC6A4 CHRM1 CHRM4

3.02e-078413DB00715
DrugImipramine

SLC6A4 CHRM1 CHRM4

8.85e-0711413DB00458
DrugNortriptyline

SLC6A4 CHRM1 CHRM4

1.18e-0612413DB00540
DrugDesipramine

SLC6A4 CHRM1 CHRM4

1.53e-0613413DB01151
DrugAmitriptyline

SLC6A4 CHRM1 CHRM4

4.34e-0618413DB00321
Drug8-iso Misoprostol

TBXA2R PLCD4 PRSS2 PTGER2

4.68e-0662414CID004183806
DrugDoxepin

SLC6A4 CHRM1 CHRM4

6.05e-0620413DB01142
Drug5-chlorohydroxyquinol

TGM1 C2

9.48e-063412CID000189666
Drug(4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride

CHRM1 CHRM4

9.48e-063412ctd:D008455
DrugRS-61756-007

TBXA2R PTGER2

9.48e-063412CID006439093
Drugiprindole

SLC6A4 MME CHRM1

1.72e-0528413CID000021722
Drugfurtrethonium

CHRM1 CHRM4

1.89e-054412ctd:C028530
DrugHyoscyamine

CHRM1 CHRM4

1.89e-054412DB00424
DrugProcyclidine

CHRM1 CHRM4

1.89e-054412DB00387
Drug5-methylfurtrethonium

CHRM1 CHRM4

1.89e-054412ctd:C008446
DrugWIN 62577

CHRM1 CHRM4

1.89e-054412ctd:C086110
DrugWIN 51708

CHRM1 CHRM4

1.89e-054412ctd:C086111
DrugAC1L1HNG

TBXA2R PTGER2

1.89e-054412CID000004206
DrugTropicamide

CHRM1 CHRM4

1.89e-054412DB00809
DrugWithaferin A [5119-48-2]; Down 200; 1uM; MCF7; HT_HG-U133A

CRYBG1 TNFRSF25 CD22 FAM120C SLC6A14

2.04e-051864153902_DN
DrugAC1MO44G

TBXA2R TGM1 MME CHRM1

2.25e-0592414CID003363161
DrugButamben [94-25-7]; Up 200; 20.6uM; PC3; HT_HG-U133A

TBXA2R TNFRSF25 DMBT1 FAM120C CNGA1

2.68e-051974155792_UP
DrugTolazoline hydrochloride [59-97-2]; Up 200; 20.4uM; MCF7; HT_HG-U133A

SLC6A4 TNFRSF25 CD22 FAM120C ABCA7

2.75e-051984154844_UP
DrugAtropine

CHRM1 CHRM4

3.15e-055412DB00572
DrugFesoterodine

CHRM1 CHRM4

3.15e-055412DB06702
DrugDarifenacin

CHRM1 CHRM4

3.15e-055412DB00496
DrugMetixene

CHRM1 CHRM4

3.15e-055412DB00340
DrugTrihexyphenidyl

CHRM1 CHRM4

3.15e-055412DB00376
DrugSolifenacin

CHRM1 CHRM4

3.15e-055412DB01591
DrugScopolamine Derivatives

CHRM1 CHRM4

3.15e-055412ctd:D012602
Drug5-(3-(3-hydroxyphenoxy)azetidin-1-yl)-5-methyl-2,2-diphenylhexanamide

CHRM1 CHRM4

3.15e-055412ctd:C568516
Drug8-acetyl-12-hydroxyheptadecanoic acid

TBXA2R PTGER2

3.15e-055412CID012042400
Drugxanomeline

CHRM1 CHRM4

3.15e-055412ctd:C075257
DrugPipecuronium

CHRM1 CHRM4

3.15e-055412ctd:D017300
DrugN-Methylscopolamine

CHRM1 CHRM4

3.15e-055412ctd:D019832
DrugTolterodine

CHRM1 CHRM4

3.15e-055412DB01036
DrugCryptenamine

CHRM1 CHRM4

3.15e-055412DB00785
DrugHomatropine Methylbromide

CHRM1 CHRM4

3.15e-055412DB00725
Drugenediyne antibiotics

SLC6A4 CHRM1

3.15e-055412CID005378630
DrugQuinuclidinyl Benzilate

CHRM1 CHRM4

3.15e-055412ctd:D011813
Drug2-methylvalerate

C2 CS

4.72e-056412CID000007341
DrugGallamine Triethiodide

CHRM1 CHRM4

4.72e-056412ctd:D005703
DrugEscitalopram

SLC6A4 CHRM1

4.72e-056412DB01175
Drugoctacosane

C2 CHIA

4.72e-056412CID000012408
Drugbrucine N-oxide

CHRM1 CHRM4

4.72e-056412ctd:C083067
DrugBrompheniramine

CHRM1 CHRM4

4.72e-056412DB00835
DrugBenzquinamide

CHRM1 CHRM4

4.72e-056412DB00767
DrugScopolamine

CHRM1 CHRM4

4.72e-056412DB00747
DrugCrotalid Venoms

CHRM1 CHRM4

4.72e-056412ctd:D003435
DrugPalladium

HLA-DRB4 HLA-DRB5

6.61e-057412ctd:D010165
DrugTiotropium Bromide

CHRM1 CHRM4

6.61e-057412ctd:D000069447
DrugAmoxapine

SLC6A4 CHRM1

8.80e-058412DB00543
DrugAL-3138

TBXA2R PTGER2

8.80e-058412CID005311237
DrugTEI-3356

TBXA2R PTGER2

8.80e-058412CID006439368
DrugAC1L1JSB

CS CHIA

8.80e-058412CID000055790
DrugAM 1241

CHRM1 CHRM4

8.80e-058412ctd:C439263
DrugCocaine

SLC6A4 CHRM1

8.80e-058412DB00907
DrugMaprotiline

CHRM1 CHRM4

8.80e-058412DB00934
Drugoxotremorine M

CHRM1 CHRM4

8.80e-058412ctd:C042743
Drugketanserin

TBXA2R SLC6A4 PLCD4 CHRM1

8.99e-05131414CID000003822
Drughyaluronan

TBXA2R PRSS2 CHIA PTGER2 PGBD3

1.06e-04263415CID000024759
DrugTei-9063

TBXA2R PTGER2

1.13e-049412CID005311245
DrugDGM-2

TGM1 CHRM1

1.13e-049412CID000016891
Drugbenzo(F)quinoxaline

C2 CHRM1

1.13e-049412CID000098494
Drugoxadiazoles

SLC6A4 CHRM1

1.13e-049412CID010523409
DrugPt-W

TGM1 C2

1.13e-049412CID000143061
DrugAC1MJ5M1

PRSS2 MME

1.13e-049412CID003086119
DrugMinaprine

SLC6A4 CHRM1

1.13e-049412DB00805
Drug17-phenyl-trinor-prostaglandin E2

TBXA2R PTGER2

1.41e-0410412CID000001450
DrugBethanechol

CHRM1 CHRM4

1.41e-0410412ctd:D018723
Drug1,2,4-thiadiazole

TGM1 CHRM1

1.41e-0410412CID006451464
DrugPromethazine

CHRM1 CHRM4

1.41e-0410412DB01069
Drugamphetamine

SLC6A4 C2 MME CS CHRM1

1.51e-04284415CID000003007
DrugU46619

TBXA2R C2 PLCD4 PTGER2 CHRM1

1.54e-04285415CID000005618
DrugDCCD

TBXA2R C2 PRSS2 PTGER2

1.56e-04151414CID000010868
Drugcitramalate

C2 CS

1.72e-0411412CID000001081
DrugPancuronium

CHRM1 CHRM4

1.72e-0411412ctd:D010197
Drugrocuronium

CHRM1 CHRM4

1.72e-0411412ctd:C061870
DrugLys-Bradykinin

PRSS2 MME PTGER2

1.73e-0460413CID000009569
Drugisocitrate

C2 PRSS2 CS CHRM1

1.76e-04156414CID000001198
DrugCaCl2

SLC6A4 C2 PRSS2 CHIA

1.76e-04156414CID000024854
Drug(?-Fluprostenol

TBXA2R PLCD4 PTGER2

1.81e-0461413CID000003391
Drugarginine methyl ester

TBXA2R PRSS2 CHRM1

1.81e-0461413CID000092932
DrugAC1L1I1P

C2 CS HLA-DRB5

1.90e-0462413CID000004385
DrugTG-2

TGM1 TGM3 PRSS2

2.00e-0463413CID000574319
DrugGR63799

TBXA2R PTGER2

2.06e-0412412CID005311224
DrugAC1Q637U

PRSS2 CHIA

2.06e-0412412CID000004869
DrugChlorprothixene

CHRM1 CHRM4

2.06e-0412412DB01239
DrugVecuronium Bromide

CHRM1 CHRM4

2.06e-0412412ctd:D014673
Drugphenylphosphonic acid

C2 MME

2.06e-0412412CID000015295
Drug5'-sulfamoyladenosine

TGM1 MME CD22

2.09e-0464413CID000097576
DrugAC1L22WP

TGM1 TGM3 CHIA

2.29e-0466413CID000065254
Drugchlorzolamide

C2 TNFRSF25

2.44e-0413412CID000165323
DrugZK118182

TBXA2R PTGER2

2.44e-0413412CID005311208
DrugMB28767

TBXA2R PTGER2

2.44e-0413412CID005311223
DrugN-0164

TBXA2R PTGER2

2.44e-0413412CID000173763
Drugalaproclate

SLC6A4 CHRM1

2.44e-0413412CID000002081
DrugNSC292567

TBXA2R C2 MCOLN1

2.50e-0468413CID000004489
Drugsilver nanoparticles

TGM1 CHIA CD22 CNGA1

2.56e-04172414CID000023954
DrugMethyl Parathion

TGM1 CHRM1 CHRM4

2.61e-0469413ctd:D008743
Diseaseaspirin-induced respiratory disease (is_implicated_in)

TBXA2R CACNG6 HLA-DRB4

4.39e-0711423DOID:0080822 (is_implicated_in)
Diseaseasthma (is_implicated_in)

TBXA2R SLC6A4 CHIA CHRM1

7.38e-05157424DOID:2841 (is_implicated_in)
DiseaseAsthma, Aspirin-Induced

TBXA2R PTGER2

1.53e-0413422C1319853
DiseaseAmphetamine-Related Disorders

SLC6A4 DCSTAMP CSMD1

1.69e-0475423C0236733
DiseaseAmphetamine Abuse

SLC6A4 DCSTAMP CSMD1

1.69e-0475423C0236807
DiseaseAmphetamine Addiction

SLC6A4 DCSTAMP CSMD1

1.69e-0475423C0236804
Diseaseneutrophil collagenase measurement

C2 ABCA13

2.34e-0416422EFO_0008248
Diseaseubiquitin carboxyl-terminal hydrolase 25 measurement

C2 HLA-DRB5

4.49e-0422422EFO_0021881
Diseasecongestive heart failure (biomarker_via_orthology)

MME CS CHRM4

4.80e-04107423DOID:6000 (biomarker_via_orthology)
Diseaseresponse to vaccine

C2 CSMD1 HLA-DRB5

7.04e-04122423EFO_0004645
Diseasecerebrospinal fluid clusterin measurement

CSMD1 ABCA13

1.14e-0335422EFO_0007657
Diseaseresponse to radiation, prostate carcinoma, erectile dysfunction

CELA2B CELA2A

1.28e-0337422EFO_0001663, EFO_0004234, GO_0009314

Protein segments in the cluster

PeptideGeneStartEntry
SIGYWLCYVNSTINP

CHRM4

436

P08173
GYPNYANCTWIIITG

CSMD1

51

Q96PZ7
CYFTNWAQYRPGLGR

CHIA

26

Q9BZP6
YFLCGWYLSNLIPGT

ABCA13

3766

Q86UQ4
NNYPCYVTGWGRLQT

CELA2A

151

P08217
PRLTYEYSWSLGCGV

CACNG6

211

Q9BXT2
LATWYLEAVCPGQYG

ABCA7

746

Q8IZY2
PWTNGSGLALCQRYY

MCOLN1

156

Q9GZU1
CSVNGFYPGSIEVRW

HLA-DRB5

146

Q30154
VWSGTEPICRQPYSY

C2

196

P06681
PNSGQSWYFLGRCYS

KDM6A

281

O15550
GQYVQYCPGTWCFIR

PTGER2

176

P43116
GPCGWKYENIYITRQ

DCSTAMP

236

Q9H295
AQVWCGTYRPEYAVN

MME

691

P08473
GQYRCYGAHNLSPRW

LILRB5

291

O75023
NNYPCYVTGWGRLQT

CELA2B

151

P08218
YIWNTLNSGRVVPGY

CS

331

O75390
LPRLYGGYQTDWVCG

FAM120C

126

Q9NX05
ELGYWLCYVNSTINP

CHRM1

401

P11229
CSVNGFYPGSIEVRW

HLA-DRB4

146

P13762
TCLGWYRQCNIIPYS

FKTN

301

O75072
PNWYEFSGCRQIGSL

CRYBG1

1566

Q9Y4K1
WCGITPQGYYRRTAE

CERCAM

181

Q5T4B2
LVISTWNGYYECRPQ

DMBT1

2151

Q9UGM3
ICPNIWLEYGQYSVG

SART3

181

Q15020
SCYGYPIQLQWLLEG

CD22

166

P20273
ATCLGYICWFQPYQG

PGBD3

301

Q8N328
GQYTLPWTCMQQGYR

PLCD4

716

Q9BRC7
YYTGVLCGLGWNPAT

TDRD9

1246

Q8NDG6
LTQPWYSGNCDRYAV

SH2D6

61

Q7Z4S9
YCANWTPGAIGLYTL

MYCBP2

2411

O75592
IWRFPYLCQTYGGGA

SLC6A18

41

Q96N87
SPVRYGQCWVFAGTL

TGM3

266

Q08188
PSGNTYYNWLFCITL

CNGA1

156

P29973
THQGINPYRCSWYGK

ZNF75CP

341

Q92670
WGYGCAQKNRPGVYT

PRSS2

216

P07478
ICTVQLVGNSWTPGY

TNFRSF25

271

Q93038
LRTGYSVPYGQCWVF

TGM1

366

P22735
VGRYTVQYPGSWCFL

TBXA2R

171

P21731
PYWSIILGYCIGTSS

SLC6A4

571

P31645
LGNVWRFPYLTYSNG

SLC6A14

56

Q9UN76
LTWIYYTRCGGPQQS

SIGLEC14

376

Q08ET2