Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionlactate transmembrane transporter activity

SLC16A3 SLC16A8

2.63e-056272GO:0015129
GeneOntologyMolecularFunctionandrosterone dehydrogenase activity

RDH16 HSD17B6

4.91e-058272GO:0047023
GeneOntologyMolecularFunctionandrostan-3-alpha,17-beta-diol dehydrogenase activity

RDH16 HSD17B6

6.30e-059272GO:0047044
GeneOntologyMolecularFunctionall-trans-retinol dehydrogenase (NAD+) activity

RDH16 HSD17B6

4.77e-0424272GO:0004745
GeneOntologyMolecularFunctionalcohol dehydrogenase (NAD+) activity

RDH16 HSD17B6

5.61e-0426272GO:0004022
GeneOntologyMolecularFunctionalcohol dehydrogenase [NAD(P)+] activity

RDH16 HSD17B6

7.48e-0430272GO:0018455
GeneOntologyMolecularFunctionsteroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

RDH16 HSD17B6

9.06e-0433272GO:0033764
GeneOntologyMolecularFunctionsteroid dehydrogenase activity

RDH16 HSD17B6

1.27e-0339272GO:0016229
GeneOntologyMolecularFunctionorganic hydroxy compound transmembrane transporter activity

SLC16A3 SLC16A8

4.02e-0370272GO:1901618
GeneOntologyMolecularFunctionmicrotubule motor activity

KIFC1 KIF16B

4.02e-0370272GO:0003777
GeneOntologyBiologicalProcessretinol metabolic process

PNPLA2 RDH16 HSD17B6

4.49e-0553273GO:0042572
GeneOntologyBiologicalProcesslactate transport

SLC16A3 SLC16A8

5.91e-059272GO:0015727
GeneOntologyBiologicalProcesslactate transmembrane transport

SLC16A3 SLC16A8

5.91e-059272GO:0035873
GeneOntologyBiologicalProcessretinoid metabolic process

PNPLA2 RDH16 HSD17B6

2.11e-0489273GO:0001523
GeneOntologyBiologicalProcessditerpenoid metabolic process

PNPLA2 RDH16 HSD17B6

2.48e-0494273GO:0016101
GeneOntologyBiologicalProcessterpenoid metabolic process

PNPLA2 RDH16 HSD17B6

3.43e-04105273GO:0006721
GeneOntologyBiologicalProcessprimary alcohol metabolic process

PNPLA2 RDH16 HSD17B6

3.53e-04106273GO:0034308
GeneOntologyCellularComponentendoplasmic reticulum quality control compartment

ERN2 EDEM2

2.32e-0417282GO:0044322
DomainMCT

SLC16A3 SLC16A8

2.16e-055282IPR004743
DomainLipome_HGMIC_fus_partner-like

LHFPL5 LHFPL3

4.53e-057282IPR019372
DomainL_HMGIC_fpl

LHFPL5 LHFPL3

4.53e-057282PF10242
DomainSc_DH/Rdtase_CS

RDH16 HSD17B6

1.25e-0335282IPR020904
DomainKinesin_motor_CS

KIFC1 KIF16B

1.71e-0341282IPR019821
DomainKinesin-like_fam

KIFC1 KIF16B

1.88e-0343282IPR027640
DomainKINESIN_MOTOR_1

KIFC1 KIF16B

1.97e-0344282PS00411
Domain-

KIFC1 KIF16B

1.97e-03442823.40.850.10
DomainKinesin_motor_dom

KIFC1 KIF16B

1.97e-0344282IPR001752
DomainKinesin

KIFC1 KIF16B

1.97e-0344282PF00225
DomainKISc

KIFC1 KIF16B

1.97e-0344282SM00129
DomainKINESIN_MOTOR_2

KIFC1 KIF16B

1.97e-0344282PS50067
DomainADH_SHORT

RDH16 HSD17B6

2.85e-0353282PS00061
Domainadh_short

RDH16 HSD17B6

3.06e-0355282PF00106
DomainSDR_fam

RDH16 HSD17B6

3.17e-0356282IPR002347
DomainMFS

SLC16A3 SLC16A8

5.92e-0377282IPR011701
DomainMFS_1

SLC16A3 SLC16A8

5.92e-0377282PF07690
DomainIg_E-set

PKHD1 MYCBP2

1.06e-02104282IPR014756
DomainMFS

SLC16A3 SLC16A8

1.14e-02108282PS50850
DomainMFS_dom

SLC16A3 SLC16A8

1.71e-02134282IPR020846
PathwayREACTOME_PROTON_COUPLED_MONOCARBOXYLATE_TRANSPORT

SLC16A3 SLC16A8

3.16e-056212MM17217
PathwayREACTOME_PROTON_COUPLED_MONOCARBOXYLATE_TRANSPORT

SLC16A3 SLC16A8

3.16e-056212M27355
PathwayREACTOME_THE_CANONICAL_RETINOID_CYCLE_IN_RODS_TWILIGHT_VISION

RDH16 HSD17B6

3.95e-0420212MM14888
PathwayREACTOME_THE_CANONICAL_RETINOID_CYCLE_IN_RODS_TWILIGHT_VISION

RDH16 HSD17B6

5.25e-0423212M27174
PathwayREACTOME_BASIGIN_INTERACTIONS

SLC16A3 SLC16A8

5.72e-0424212MM17215
PathwayREACTOME_BASIGIN_INTERACTIONS

SLC16A3 SLC16A8

6.21e-0425212M4974
PathwayWP_FATTY_ACID_BETAOXIDATION

GCDH PNPLA2

1.15e-0334212M39596
PathwayWP_FATTY_ACID_BETAOXIDATION

GCDH PNPLA2

1.15e-0334212MM15937
Pubmed

Basolateral sorting signals regulating tissue-specific polarity of heteromeric monocarboxylate transporters in epithelia.

SLC16A3 SLC16A8

6.25e-07228221199217
Pubmed

The tetraspan LHFPL5 is critical to establish maximal force sensitivity of the mechanotransduction channel of cochlear hair cells.

LHFPL5 LHFPL3

6.25e-07228236917610
Pubmed

Glucose affects monocarboxylate cotransporter (MCT) 1 expression during mouse preimplantation development.

SLC16A3 SLC16A8

1.87e-06328216514190
Pubmed

Polarized expression of monocarboxylate transporters in human retinal pigment epithelium and ARPE-19 cells.

SLC16A3 SLC16A8

3.75e-06428212657613
Pubmed

Cysteine 159 delineates a hinge region of the alternating access monocarboxylate transporter 1 and is targeted by cysteine-modifying inhibitors.

SLC16A3 SLC16A8

6.24e-06528233999492
Pubmed

Genetic expression of monocarboxylate transporters during human and murine oocyte maturation and early embryonic development.

SLC16A3 SLC16A8

6.24e-06528212056458
Pubmed

Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4: the ancillary protein for the insensitive MCT2 is EMBIGIN (gp70).

SLC16A3 SLC16A8

9.36e-06628215917240
Pubmed

Novel function of LHFPL2 in female and male distal reproductive tract development.

LHFPL5 LHFPL3

1.31e-05728226964900
Pubmed

The glucose-lactic acid cycle and gluconeogenesis.

SLC16A3 SLC16A8

4.10e-05122827273846
Pubmed

A missense mutation in the previously undescribed gene Tmhs underlies deafness in hurry-scurry (hscy) mice.

LHFPL5 LHFPL3

4.10e-051228215905332
Pubmed

The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond.

SLC16A3 SLC16A8

5.65e-051428212739169
Pubmed

Quantitative Protein Expression in the Human Retinal Pigment Epithelium: Comparison Between Apical and Basolateral Plasma Membranes With Emphasis on Transporters.

SLC16A3 SLC16A8

9.49e-051828231791063
Pubmed

Hypoxic regulation of hand1 controls the fetal-neonatal switch in cardiac metabolism.

PNPLA2 SLC16A3

2.17e-042728224086110
Pubmed

All kinesin superfamily protein, KIF, genes in mouse and human.

KIFC1 KIF16B

4.09e-043728211416179
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

CLIP4 NDST1 NEUROD2 REPS2 LNX1 MYCBP2

4.71e-04128528635914814
Pubmed

Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.

GCDH MYCBP2 KIFC1

6.27e-0420928326389662
Cytoband6p12.2

PKHD1 TMEM14A

3.25e-05142826p12.2
CytobandEnsembl 112 genes in cytogenetic band chr6p12

PKHD1 TMEM14A

3.41e-03142282chr6p12
GeneFamilyKinesins|Pleckstrin homology domain containing

KIFC1 KIF16B

1.05e-0346192622
GeneFamilyShort chain dehydrogenase/reductase superfamily

RDH16 HSD17B6

2.85e-0376192743
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_alveolar-AT1|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

RANBP17 NDST1 REPS2 HSD17B6

7.14e-062002843d51aebf626dd4656ab4aac8a20d761b8062c42d
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAS1R1 REPS2 LNX1

1.31e-04158283e7db50d6dfaf7280a73a0d5b5aa4f43ea2762d72
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAS1R1 REPS2 LNX1

1.31e-0415828312661763d1c309106801cb710c04cd2b62d16cba
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAS1R1 REPS2 LNX1

1.31e-041582830792c39e6fc0745095af7812de2d50949540d60f
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PKHD1 RANBP17 HSD17B6

1.33e-04159283e6ff9d2bce62bf9ea173af80b688eeb40fa4ea4c
ToppCellICU-SEP-Myeloid-cDC1|ICU-SEP / Disease, Lineage and Cell Type

RDH16 TMEM14A KIF16B

1.38e-041612839fb73909fc2ec99f96ca2eed1a053bce89de7d16
ToppCelldroplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC16A3 SZT2 CREB3L2

1.48e-0416528394a5211072464fc24592bb107a853ce832e816fe
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Cerebellum / BrainAtlas - Mouse McCarroll V32

CLIP4 LHFPL5 REPS2

1.54e-041672839efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCellCerebellum-Neuronal-Inhibitory|Cerebellum / BrainAtlas - Mouse McCarroll V32

CLIP4 LHFPL5 REPS2

1.54e-04167283904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

ERN2 TMEM14A KIF16B

1.68e-041722831215f61f115b042f84721b64c2ed1f48081535f1
ToppCell5'-Adult-Distal_Rectal-Hematopoietic-Plasma_cells-IgA_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NDST1 REPS2 CREB3L2

1.71e-0417328309cd878c33534bd476d6a4880f5582076189da8c
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

RANBP17 REPS2 HSD17B6

1.71e-04173283b799c06a6a5754668e789f70c0c8bc1508568575
ToppCell5'-Adult-Distal_Rectal-Hematopoietic-Plasma_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NDST1 REPS2 CREB3L2

1.71e-0417328362abaaaf48cabd1423f17fb27c33b75ea88867f4
ToppCellfacs-Marrow-T_cells-18m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POPDC2 CREB3L2 EDEM2

1.73e-041742833b1ee39e85e5f0d6b17fb3051dbfae66cb2be6ee
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

REPS2 ERN2 HSD17B6

1.85e-04178283f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

RANBP17 REPS2 HSD17B6

1.89e-04179283cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCellAT1-AT2_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

RANBP17 REPS2 HSD17B6

1.95e-04181283ca23ce4f2c7b684d8ddd0e8619b3b696023d75e3
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RANBP17 NDST1 HSD17B6

2.04e-04184283ca940a4f4970285ed284d5517d142abab0682044
ToppCellHealthy-multiplets|Healthy / disease group, cell group and cell class

TMEM14A KIFC1 KIF16B

2.11e-041862832ec999b97e95afb898f8083042b0f188d3d234bc
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 REPS2 LHFPL3

2.11e-04186283f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 REPS2 LHFPL3

2.14e-04187283c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 REPS2 LHFPL3

2.18e-04188283af740fa78542438fdff627ea1f74f4eee43316be
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RANBP17 NDST1 HSD17B6

2.28e-04191283a15e34ad7dbf3f2f13d5e23ce3ffb6d08fd1f9f0
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

PKHD1 RANBP17 HSD17B6

2.28e-04191283d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellAT1_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

RANBP17 NDST1 REPS2

2.32e-041922830444f9e9cef7403e220e862b5a787443d3f5c9ac
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KIFC1 EDEM2 KIF16B

2.39e-041942830e9830ad070c47acaa952400bf2a3ddbff664a2f
ToppCell(7)_MNP-(7)_DC_1|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)

TMEM14A KIFC1 KIF16B

2.39e-041942838dbe0188e2af6f14b3b44e5213fbdd581128082f
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RANBP17 NDST1 HSD17B6

2.42e-0419528368f4cc84b5ae7f4159b780c78e4b66c94211779a
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RANBP17 NDST1 REPS2

2.42e-04195283a71ba5e4043e2d35a45a2c60a96b087e31832345
ToppCellnormal_Lung-Epithelial_cells-AT1|normal_Lung / Location, Cell class and cell subclass

RANBP17 NDST1 HSD17B6

2.42e-04195283569d1ebc5a5aa110a2430b096755ae35354040c4
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RANBP17 NDST1 HSD17B6

2.42e-041952832a1863f4b9fe73c30b0b1acf9b12fc98ef65040f
ToppCellNasal_Brush-Epithelial-Goblet_1|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

PNPLA2 SLC16A3 ERN2

2.46e-04196283e16f0831f1f677b28e4a8014f0aede7e713d4f04
ToppCellNasal_Brush-Epithelial-Goblet_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

PNPLA2 SLC16A3 ERN2

2.46e-0419628371e88d9ca28168732bd91f2d4f8f53bb4187963a
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Basal_3|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

RANBP17 RDH16 LNX1

2.50e-041972832cff37f9d33951840a8f52ccbba6ca1a4bbe3ad9
ToppCellSepsis-ICU-SEP-Myeloid-cDC1|ICU-SEP / Disease, condition lineage and cell class

RDH16 TMEM14A KIF16B

2.50e-04197283e3174e90ea6136f1aa3a4a185b86458e35d51fd4
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Basal_3|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

RANBP17 RDH16 LNX1

2.50e-041972834f8f23b1ef2eae9d300bd2c1a5cb7ef0163858a1
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Basal_3-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RANBP17 RDH16 LNX1

2.50e-041972830f37afad46b94c748a149d9ee681472d7a3e6937
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 REPS2 LHFPL3

2.50e-041972837e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RANBP17 NDST1 REPS2

2.50e-041972838d5097898dd01cedb04cb694cb480c931e08462c
ToppCellmoderate-Epithelial-Secretory|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PNPLA2 SLC16A3 ERN2

2.54e-041982837ecce5e266bb08797088cc8f8309e0c7b48df5c9
ToppCellBiopsy_Control_(H.)-Epithelial-SCGB3A2+|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

RANBP17 ERN2 HSD17B6

2.54e-041982831fe51f4beca0eef4ff117e6edaa646e35c0f9629
ToppCellNS-control-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RANBP17 ERN2 MYCBP2

2.57e-0419928332bdfff40fd442b88489c8b0f79af3927a51a03c
ToppCelldistal-Epithelial-Alveolar_Epithelial_Type_1-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RANBP17 NDST1 HSD17B6

2.57e-04199283c1daa481f88d5281b6b5ea8ec8bb70cc0907d613
ToppCellproximal-Epithelial-Alveolar_Epithelial_Type_1|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RANBP17 NDST1 HSD17B6

2.61e-04200283c1345893e6947ccf9b41282d0e4428dbfb8bcc27
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RANBP17 ERN2 LNX1

2.61e-04200283d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellproximal-Epithelial-Alveolar_Epithelial_Type_1-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RANBP17 NDST1 HSD17B6

2.61e-04200283b652bc73adfdeccbdcd74497ab6e2085e5c95e88
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RANBP17 ERN2 LNX1

2.61e-042002830eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCellproximal-3-Epithelial-Alveolar_Epithelial_Type_1|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RANBP17 NDST1 HSD17B6

2.61e-0420028351f8fc43c069f2c4e75588d28ae6deb5d7ed2c86
ToppCellSepsis-Int-URO-Myeloid-tDC|Int-URO / Disease, condition lineage and cell class

LNX1 TMEM14A CREB3L2

2.61e-04200283f5d0497a72da21cad24e0ef51c3dc4d024dbf294
ComputationalGenes in the cancer module 218.

SLC16A3 SLC16A8

5.52e-0420192MODULE_218
ComputationalGenes in the cancer module 186.

SLC16A3 SLC16A8

5.52e-0420192MODULE_186
ComputationalGenes in the cancer module 71.

SLC16A3 SLC16A8

6.70e-0422192MODULE_71
ComputationalNeighborhood of IGF1

RDH16 HSD17B6

9.38e-0426192GNF2_IGF1
DrugEstradiol-17 beta [50-28-2]; Down 200; 14.6uM; MCF7; HT_HG-U133A

RANBP17 NDST1 GCDH PNPLA2 REPS2

3.67e-061952855318_DN
Drugnordihydroguaiaretic acid; Down 200; 1uM; HL60; HT_HG-U133A

RANBP17 REPS2 SLC16A3 SZT2 HSD17B6

3.76e-061962856182_DN
Drughaloperidol; Down 200; 10uM; HL60; HT_HG-U133A

RANBP17 NDST1 PNPLA2 REPS2 HSD17B6

3.76e-061962856203_DN
Diseaseautosomal recessive nonsyndromic deafness 67 (implicated_via_orthology)

LHFPL5 LHFPL3

2.60e-063282DOID:0110518 (implicated_via_orthology)
Diseasestachydrine measurement

PKHD1 LHFPL3

2.42e-058282EFO_0021169
Diseasearginine measurement

GCDH HSD17B6

2.17e-0423282EFO_0020990
Diseaseschizophrenia, type 2 diabetes mellitus

NEUROD2 MYCBP2

7.65e-0443282MONDO_0005090, MONDO_0005148
Diseasekeratoconus

PKHD1 PNPLA2

1.79e-0366282MONDO_0015486
Diseasemigraine disorder, Headache

RDH16 HSD17B6

3.02e-0386282HP_0002315, MONDO_0005277
Diseaseneuroimaging measurement

PKHD1 NEUROD2 LNX1 SZT2 SLC16A8

3.03e-031069285EFO_0004346
Diseaseupper face morphology measurement

LHFPL3 CREB3L2

3.82e-0397282EFO_0010949
Diseasefibrinogen measurement

PARP10 LHFPL3

4.80e-03109282EFO_0004623
Diseasecortical surface area measurement

PKHD1 LNX1 MYCBP2 LHFPL3 EDEM2

8.00e-031345285EFO_0010736
Diseaseobsolete_red blood cell distribution width

PARP10 GCDH NEUROD2 PAQR3 HSD17B6

8.05e-031347285EFO_0005192

Protein segments in the cluster

PeptideGeneStartEntry
GGVQYFSCSPRYGIF

CLIP4

531

Q8N3C7
FEGYNACVFAYGQTG

KIF16B

91

Q96L93
LCGNYVSFGVFKLYG

RANBP17

841

Q9H2T7
GILGCYVSGVFYAFY

PAQR3

151

Q6TCH7
VLGACFVVTGFAYGF

SLC16A8

21

O95907
SFAGCGFLGVYYVGV

PNPLA2

11

Q96AD5
GDYGGLVVFCIFFGI

SLC16A3

316

O15427
IFSAGCVFYYVLSGG

ERN2

706

Q76MJ5
CVFYYVLSGGSHPFG

ERN2

711

Q76MJ5
TPQAGYFGLFSYCVG

LHFPL5

56

Q8TAF8
GYPVCIFAYGQTGSG

KIFC1

401

Q9BW19
YGECILGAGGYIFNT

EDEM2

461

Q9BV94
DKYCVAYGVGIIGFF

NDST1

156

P52848
AGSLGFCIVGGYEEY

LNX1

646

Q8TBB1
FFVGGYCVSKYGVEA

HSD17B6

171

O14756
KGYGCAGVSSVAYGL

GCDH

111

Q92947
YTSGFGAFRILDCGY

KRTAP20-3

21

Q3LI60
CFAVAFGSFFQGYGP

CREB3L2

386

Q70SY1
FCGRNATVYGKGVYF

PARP10

906

Q53GL7
FVQVGGVYSYDCSFG

SZT2

291

Q5T011
LFGGGYCISKYGVEA

RDH16

171

O75452
YGFKCFAIGYEFSPG

MYCBP2

2136

O75592
IEGNRVCGAGYGYFF

PKHD1

2331

P08F94
SSGFGGYFLPKCYVI

TAS1R1

801

Q7RTX1
CGAKRVGYFGPTQFY

REPS2

96

Q8NFH8
AGLFVGCLAGYGAYR

TMEM14A

31

Q9Y6G1
FMGGSGVYGCFYLFG

POPDC2

41

Q9HBU9
GVYGCFYLFGFLSAG

POPDC2

46

Q9HBU9
GYFGLFHYCIGNGFS

LHFPL3

71

Q86UP9
CAAYETLYAAAGGGG

NEUROD2

271

Q15784