Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsodium:bicarbonate symporter activity

SLC4A7 SLC4A8 SLC4A10

1.48e-0561833GO:0008510
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH3 DNAH10 DNAH8 DNAH9

1.89e-05181834GO:0008569
GeneOntologyMolecularFunctiontransmembrane transporter activity

ABCA1 SLC4A7 SLC4A8 HCN4 TMEM165 AQP11 HCN3 PKD1L1 SLCO3A1 CACHD1 SLC7A14 SLC47A2 NDUFS8 KCNV1 CATSPER2 SV2B SLC22A4 SCN7A ABCD3 SLC4A10 CACNA1G SLC49A3 CACNG4 SLC2A12 SLC26A6 CHP1

2.90e-05118018326GO:0022857
GeneOntologyMolecularFunctionmicrotubule motor activity

KIF21B DNAH3 DNAH10 STARD9 DNAH8 DNAH9

4.40e-05701836GO:0003777
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

HCN4 HCN3 SCN7A CACNA1G

8.72e-05261834GO:0005248
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC4A7 SLC4A8 HCN4 TMEM165 HCN3 PKD1L1 CACHD1 KCNV1 CATSPER2 SCN7A SLC4A10 CACNA1G CACNG4 CHP1

1.03e-0446518314GO:0046873
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH3 DNAH10 DNAH8 DNAH9

1.18e-04281834GO:0051959
GeneOntologyMolecularFunctiontransporter activity

ABCA1 SLC4A7 SLC4A8 HCN4 TMEM165 AQP11 HCN3 PKD1L1 SLCO3A1 CACHD1 SLC7A14 SLC47A2 NDUFS8 KCNV1 CATSPER2 SV2B SLC22A4 SCN7A ABCD3 SLC4A10 CACNA1G SLC49A3 CACNG4 SLC2A12 SLC26A6 CHP1

1.25e-04128918326GO:0005215
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC4A7 SLC4A8 HCN4 HCN3 SCN7A SLC4A10 CACNA1G CHP1

1.84e-041711838GO:0015081
GeneOntologyMolecularFunctionbicarbonate transmembrane transporter activity

SLC4A7 SLC4A8 SLC4A10 SLC26A6

2.01e-04321834GO:0015106
GeneOntologyMolecularFunctionsolute:inorganic anion antiporter activity

SLC4A7 SLC4A8 SLC4A10 SLC26A6

2.01e-04321834GO:0005452
GeneOntologyMolecularFunctionchloride:bicarbonate antiporter activity

SLC4A8 SLC4A10 SLC26A6

2.02e-04131833GO:0140900
GeneOntologyMolecularFunctionbicarbonate:monoatomic anion antiporter activity

SLC4A8 SLC4A10 SLC26A6

2.02e-04131833GO:0140829
GeneOntologyMolecularFunctionmonoatomic cation:bicarbonate symporter activity

SLC4A7 SLC4A8 SLC4A10

2.02e-04131833GO:0140410
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC4A7 SLC4A8 HCN4 TMEM165 AQP11 HCN3 PKD1L1 CACHD1 SLC47A2 NDUFS8 KCNV1 CATSPER2 SCN7A SLC4A10 CACNA1G CACNG4 SLC26A6 CHP1

2.18e-0475818318GO:0015318
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC4A7 SLC4A8 HCN4 TMEM165 HCN3 PKD1L1 CACHD1 SLC47A2 NDUFS8 KCNV1 CATSPER2 SCN7A SLC4A10 CACNA1G CACNG4 CHP1

2.23e-0462718316GO:0022890
GeneOntologyMolecularFunctionATP hydrolysis activity

KIF21B DNAH3 ABCA1 DNAH10 CHD2 HSPA13 MDN1 ENTPD1 ABCD3 MTREX DHX34 DNAH8 DNAH9

2.24e-0444118313GO:0016887
GeneOntologyMolecularFunctionbenzaldehyde dehydrogenase (NAD+) activity

ALDH1A1 ALDH3B1

2.49e-0431832GO:0018479
GeneOntologyMolecularFunctionsodium,bicarbonate:chloride antiporter activity

SLC4A8 SLC4A10

2.49e-0431832GO:0140892
GeneOntologyMolecularFunctionantiporter activity

SLC4A7 SLC4A8 TMEM165 SLC47A2 SLC4A10 SLC26A6 CHP1

2.86e-041381837GO:0015297
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH3 DNAH10 DNAH8 DNAH9

3.56e-04371834GO:0045505
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC4A7 SLC4A8 TMEM165 SLCO3A1 SLC47A2 SLC22A4 SLC4A10 SLC2A12 SLC26A6 CHP1

4.18e-0429618310GO:0015291
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC4A7 SLC4A8 HCN4 TMEM165 HCN3 PKD1L1 CACHD1 SLC47A2 NDUFS8 KCNV1 CATSPER2 SCN7A SLC4A10 CACNA1G CACNG4 CHP1

4.20e-0466418316GO:0008324
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ABCA1 SLC4A7 SLC4A8 TMEM165 SLCO3A1 SLC47A2 NDUFS8 SLC22A4 ABCD3 SLC4A10 SLC2A12 SLC26A6 CHP1

4.73e-0447718313GO:0022804
GeneOntologyMolecularFunctionbenzaldehyde dehydrogenase [NAD(P)+] activity

ALDH1A1 ALDH3B1

4.95e-0441832GO:0019115
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

HCN4 HCN3 CACHD1 KCNV1 CATSPER2 CACNA1G CACNG4

5.13e-041521837GO:0022843
GeneOntologyMolecularFunctionATP-dependent activity

KIF21B DNAH3 ABCA1 WAPL DNAH10 CHD2 HSPA13 MDN1 STARD9 ENTPD1 ABCD3 MTREX DHX34 DNAH8 DNAH9

5.52e-0461418315GO:0140657
GeneOntologyMolecularFunctioncytoskeletal motor activity

KIF21B DNAH3 DNAH10 STARD9 DNAH8 DNAH9

7.70e-041181836GO:0003774
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

CACHD1 CATSPER2 CACNA1G CACNG4

8.25e-04461834GO:0005245
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC4A7 SLC4A8 HCN4 TMEM165 HCN3 PKD1L1 CACHD1 SLC47A2 NDUFS8 KCNV1 CATSPER2 SCN7A SLC4A10 CACNA1G CACNG4 SLC26A6 CHP1

1.03e-0379318317GO:0015075
GeneOntologyMolecularFunctionsodium channel activity

HCN4 HCN3 SCN7A CACNA1G

1.31e-03521834GO:0005272
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

HCN4 HCN3 CACHD1 KCNV1 CATSPER2 CACNA1G CACNG4

1.47e-031821837GO:0005244
GeneOntologyMolecularFunctioncalcium channel regulator activity

MICU1 NRXN3 CACNG4 TNNI3

1.51e-03541834GO:0005246
GeneOntologyMolecularFunctionvoltage-gated channel activity

HCN4 HCN3 CACHD1 KCNV1 CATSPER2 CACNA1G CACNG4

1.57e-031841837GO:0022832
GeneOntologyMolecularFunction3-chloroallyl aldehyde dehydrogenase activity

ALDH1A1 ALDH3B1

1.70e-0371832GO:0004028
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

TMEM165 PKD1L1 CACHD1 CATSPER2 CACNA1G CACNG4

2.72e-031511836GO:0015085
GeneOntologyMolecularFunctionarmadillo repeat domain binding

CTNNBIP1 CNOT1

2.88e-0391832GO:0070016
GeneOntologyMolecularFunctionglyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity

ALDH1A1 ALDH3B1

2.88e-0391832GO:0043878
GeneOntologyBiologicalProcessregulation of pH

SLC4A7 SLC4A8 TMEM165 AQP11 CHP2 SLC4A10 SLC26A6 CHP1

1.05e-051201808GO:0006885
GeneOntologyBiologicalProcessregulation of intracellular pH

SLC4A7 SLC4A8 TMEM165 AQP11 SLC4A10 SLC26A6 CHP1

1.85e-05941807GO:0051453
GeneOntologyBiologicalProcessregulation of cellular pH

SLC4A7 SLC4A8 TMEM165 AQP11 SLC4A10 SLC26A6 CHP1

2.96e-051011807GO:0030641
GeneOntologyBiologicalProcesssodium ion transport

SLC4A7 SLC4A8 HCN4 HCN3 MAGED2 SLC22A4 CHP2 SCN7A SLC4A10 CACNA1G CHP1

3.13e-0527518011GO:0006814
GeneOntologyCellularComponentcalcium channel complex

PKD1L1 CACHD1 MICU1 CATSPER2 CACNA1G CACNG4

4.34e-05731836GO:0034704
GeneOntologyCellularComponentcation channel complex

HCN4 HCN3 PKD1L1 CACHD1 MICU1 KCNV1 CATSPER2 SCN7A CACNA1G CACNG4

4.41e-0523518310GO:0034703
GeneOntologyCellularComponentaxonemal dynein complex

DNAH3 DNAH10 DNAH8 DNAH9

6.23e-05251834GO:0005858
GeneOntologyCellularComponentbasal plasma membrane

ABCA1 SLC4A7 SLC4A8 HCN4 SLCO3A1 CLDN7 MSN SLC22A4 ENTPD1 SLC4A10 SLC26A6

3.00e-0435418311GO:0009925
GeneOntologyCellularComponentHCN channel complex

HCN4 HCN3

4.52e-0441832GO:0098855
GeneOntologyCellularComponentbasal part of cell

ABCA1 SLC4A7 SLC4A8 HCN4 SLCO3A1 CLDN7 MSN SLC22A4 ENTPD1 SLC4A10 SLC26A6

5.21e-0437818311GO:0045178
GeneOntologyCellularComponentmonoatomic ion channel complex

HCN4 HCN3 PKD1L1 CACHD1 MICU1 KCNV1 CATSPER2 SCN7A CACNA1G CACNG4 SLC26A6

5.21e-0437818311GO:0034702
GeneOntologyCellularComponentbasolateral plasma membrane

ABCA1 SLC4A7 SLC4A8 HCN4 SLCO3A1 CLDN7 MSN ENTPD1 SLC4A10 SLC26A6

5.39e-0432018310GO:0016323
GeneOntologyCellularComponentvoltage-gated calcium channel complex

CACHD1 CATSPER2 CACNA1G CACNG4

6.96e-04461834GO:0005891
GeneOntologyCellularComponenttransporter complex

HCN4 HCN3 PKD1L1 CACHD1 NDUFS8 MICU1 KCNV1 CATSPER2 SCN7A CACNA1G CACNG4 SLC26A6 CHP1

1.15e-0355018313GO:1990351
GeneOntologyCellularComponentdynein complex

DNAH3 DNAH10 DNAH8 DNAH9

1.28e-03541834GO:0030286
DomainATPase_dyneun-rel_AAA

DNAH3 DNAH10 MDN1 DNAH8 DNAH9

1.51e-07141815IPR011704
DomainAAA_5

DNAH3 DNAH10 MDN1 DNAH8 DNAH9

1.51e-07141815PF07728
DomainDynein_heavy_chain_D4_dom

DNAH3 DNAH10 DNAH8 DNAH9

7.92e-06141814IPR024317
DomainDynein_HC_stalk

DNAH3 DNAH10 DNAH8 DNAH9

7.92e-06141814IPR024743
DomainDynein_heavy_dom-2

DNAH3 DNAH10 DNAH8 DNAH9

7.92e-06141814IPR013602
DomainDHC_N2

DNAH3 DNAH10 DNAH8 DNAH9

7.92e-06141814PF08393
DomainMT

DNAH3 DNAH10 DNAH8 DNAH9

7.92e-06141814PF12777
DomainAAA_8

DNAH3 DNAH10 DNAH8 DNAH9

7.92e-06141814PF12780
DomainDHC_fam

DNAH3 DNAH10 DNAH8 DNAH9

1.07e-05151814IPR026983
DomainDynein_heavy

DNAH3 DNAH10 DNAH8 DNAH9

1.07e-05151814PF03028
DomainDynein_heavy_dom

DNAH3 DNAH10 DNAH8 DNAH9

1.07e-05151814IPR004273
DomainARM-type_fold

RALGAPA1 SMG1 RELCH WAPL UNC45A RALGAPA2 URB1 USO1 NOM1 GPRASP2 TBCD TANGO6 SYMPK

2.76e-0533918113IPR016024
DomainANION_EXCHANGER_2

SLC4A7 SLC4A8 SLC4A10

3.04e-0571813PS00220
DomainANION_EXCHANGER_1

SLC4A7 SLC4A8 SLC4A10

3.04e-0571813PS00219
DomainDHC_N1

DNAH10 DNAH8 DNAH9

4.84e-0581813PF08385
DomainDynein_heavy_dom-1

DNAH10 DNAH8 DNAH9

4.84e-0581813IPR013594
Domain-

SLC4A7 SLC4A8 SLC4A10

7.20e-05918133.40.1100.10
DomainBand3_cytoplasmic_dom

SLC4A7 SLC4A8 SLC4A10

7.20e-0591813IPR013769
DomainBand_3_cyto

SLC4A7 SLC4A8 SLC4A10

7.20e-0591813PF07565
DomainPTrfase/Anion_transptr

SLC4A7 SLC4A8 SLC4A10

1.02e-04101813IPR016152
DomainHCO3_transpt_euk

SLC4A7 SLC4A8 SLC4A10

1.02e-04101813IPR003020
DomainHCO3_cotransp

SLC4A7 SLC4A8 SLC4A10

1.02e-04101813PF00955
DomainHCO3_transpt_C

SLC4A7 SLC4A8 SLC4A10

1.02e-04101813IPR011531
DomainAAA

DNAH3 ABCA1 DNAH10 MDN1 ABCD3 DNAH8 DNAH9

5.15e-041441817SM00382
DomainAAA+_ATPase

DNAH3 ABCA1 DNAH10 MDN1 ABCD3 DNAH8 DNAH9

5.15e-041441817IPR003593
DomainIon_trans_N

HCN4 HCN3

5.53e-0441812IPR013621
DomainIon_trans_N

HCN4 HCN3

5.53e-0441812PF08412
DomainIon_trans_dom

HCN4 HCN3 KCNV1 CATSPER2 SCN7A CACNA1G

8.56e-041141816IPR005821
DomainIon_trans

HCN4 HCN3 KCNV1 CATSPER2 SCN7A CACNA1G

8.56e-041141816PF00520
DomainNa/HCO3_transpt

SLC4A8 SLC4A10

9.16e-0451812IPR003024
DomainAnion_exchange

SLC4A7 SLC4A10

9.16e-0451812IPR001717
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

SMG1 HIVEP1 CTTNBP2 VWF ILK KDM5A OBSCN LAMA2 MYOZ3 CHD2 TRIP11 MSN LUC7L AMOT

4.46e-074971831423414517
Pubmed

Identification, tissue specific expression, and chromosomal localisation of several human dynein heavy chain genes.

DNAH3 DNAH10 DNAH9

5.71e-074183311175280
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

SMG1 MRPS18B AGPAT2 MRPS27 PSMD12 ITPRID2 UNC45A GOSR2 STAT3 NDUFS8 LUC7L RINT1 URB1 MDN1 NOM1 POP1 ABCD3 SMU1 MTREX CNOT1 COG4 PCK2 CUX1 CHP1

6.40e-0714401832430833792
Pubmed

Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.

ABCA1 WAPL ILK MED16 MRPS27 QRICH1 PTGS1 NDUFS8 MICU1 RINT1 MDN1 GLS PCK2 TBCD

6.80e-075151831431617661
Pubmed

Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.

ABCA1 WAPL SLC4A7 SLC4A8 MRPS18B PGAP6 SLC7A14 NDUFS8 FICD MAGED2 SLC4A10 CUX1

7.23e-073711831215747579
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

EEFSEC SLC4A7 KDM5A MED16 MRPS18B ESR1 AGPAT2 MRPS27 CHD2 ITPRID2 UNC45A SRBD1 NDUFS8 MICU1 URB1 MDN1 ACAD11 NOM1 POP1 ABCD3 SMU1 MTREX SGF29 CHP1

1.26e-0614971832431527615
Pubmed

Immunocytochemical identification of electroneutral Na⁺-coupled HCO₃⁻ transporters in freshly dissociated mouse medullary raphé neurons.

SLC4A7 SLC4A8 SLC4A10

1.42e-065183323500099
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

SMG1 HIVEP1 TMEM165 MRPS27 CHD2 PPFIA3 TRIP11 MDN1 GUCY1B2 ACAD11 DDHD1 GLS CNOT1 PCK2 CUX1

1.64e-066381831531182584
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

HIVEP1 KDM5A UNC45A USO1 AMOT GLS ABCD3 ARL14EP CNOT1 GPRASP2 CUX1 TANGO6

2.50e-064181831234709266
Pubmed

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.

HIVEP1 LAMA2 CHD2 RALGAPA2 SEC22A TRIP11 MICU1 CATSPER2 MAGED2 AMOT STARD9 LMLN IL21 RNF145 HYDIN

3.96e-066861831529987050
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

RALGAPA1 KIF21B SMG1 RELCH WAPL CACHD1 NRXN3 AMOT DDHD1 CACNA1G MTREX DHX34 CNOT1

5.16e-065291831314621295
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

EEFSEC SMG1 WAPL MSN RINT1 ACAD11 NOM1 DDHD1 SLC22A4 POP1 ABCD3 MTREX DHX34 COG4

9.93e-066501831438777146
Pubmed

The HIV matrix protein p17 induces hepatic lipid accumulation via modulation of nuclear receptor transcriptoma.

ABCA1 ESR1 STAT3 PCK2

1.18e-0527183426469385
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

ASNSD1 EEFSEC KDM5A MRPS18B CTSC MRPS27 CHD2 UNC45A STAT3 BUD23 LUC7L ACAD11 MAGED2 USO1 STARD9 NOM1 POP1 SMU1 MTREX CNOT1 PCK2

1.22e-0513711832136244648
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

EEFSEC MED16 MRPS18B MRPS27 SRBD1 URB1 MDN1 ACAD11 MAGED2 GLE1 NOM1 POP1 MTREX SGF29 CNOT1

1.31e-057591831535915203
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

RALGAPA1 HIVEP1 SLC4A7 ILK KDM5A ITPRID2 UNC45A TRIP11 STAT3 LUC7L BORCS5 MDN1 USO1 AMOT STARD9 MTREX

1.43e-058611831636931259
Pubmed

Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.

PDE4C ZSWIM5 RALGAPA2 GLE1 POP1 CNOT1 KLHL17

1.49e-05149183722664934
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

RAD18 SLC4A7 MED16 TMEM165 CTSC CHD2 GOSR2 SEC22A STAT3 PKMYT1 RINT1 USO1 GLE1 AMOT NOM1 ABCD3 CNOT1 TBCD SYMPK

2.15e-0512031831929180619
Pubmed

Human transcription factor protein interaction networks.

ASNSD1 SMG1 RAD18 HIVEP1 DNAH10 KDM5A MRPS18B ESR1 MRPS27 PSMD12 STAT3 MSN BUD23 MAGED2 ABCD3 HERC1 SGF29 CNOT1 CUX1 TANGO6 SYMPK

2.26e-0514291832135140242
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

ABCA1 CTSC RALGAPA2 MDN1 ENTPD1 POP1 CACNA1G SLC26A6 EPHA7 KLHL17

2.48e-053631831014691545
Pubmed

Intracellular interaction of von Willebrand factor and factor VIII depends on cellular context: lessons from platelet-expressed factor VIII.

VWF F8

2.75e-052183215731176
Pubmed

Rise of levels of von Willebrand factor and factor VIII with age: Role of genetic and acquired risk factors.

VWF F8

2.75e-052183233221577
Pubmed

Mechano-covalent protection of coagulation factor VIII by von Willebrand factor.

VWF F8

2.75e-052183236240294
Pubmed

Common and rare von Willebrand factor (VWF) coding variants, VWF levels, and factor VIII levels in African Americans: the NHLBI Exome Sequencing Project.

VWF F8

2.75e-052183223690449
Pubmed

Influence of single nucleotide polymorphisms in factor VIII and von Willebrand factor genes on plasma factor VIII activity: the ARIC Study.

VWF F8

2.75e-052183222219226
Pubmed

The role of VWF in the immunogenicity of FVIII.

VWF F8

2.75e-052183218549909
Pubmed

The acidic region of the factor VIII light chain and the C2 domain together form the high affinity binding site for von willebrand factor.

VWF F8

2.75e-05218329218428
Pubmed

The affinity and stoichiometry of binding of human factor VIII to von Willebrand factor.

VWF F8

2.75e-05218327756647
Pubmed

Hemostatic and inflammatory risk factors for intracerebral hemorrhage in a pooled cohort.

VWF F8

2.75e-052183218535282
Pubmed

Maternal dietary choline deficiency alters angiogenesis in fetal mouse hippocampus.

VWF F8

2.75e-052183220624989
Pubmed

The influence of von Willebrand factor on factor VIII activity measurements.

VWF F8

2.75e-052183218983499
Pubmed

Factor VIII and von Willebrand factor changes during normal pregnancy and puerperium.

VWF F8

2.75e-052183214517489
Pubmed

Surface-exposed hemophilic mutations across the factor VIII C2 domain have variable effects on stability and binding activities.

VWF F8

2.75e-052183215471879
Pubmed

von Willebrand factor variant p.Arg924Gln marks an allele associated with reduced von Willebrand factor and factor VIII levels.

VWF F8

2.75e-052183220492463
Pubmed

Solution structure of the major factor VIII binding region on von Willebrand factor.

VWF F8

2.75e-052183224700780
Pubmed

Factor VIII alters tubular organization and functional properties of von Willebrand factor stored in Weibel-Palade bodies.

VWF F8

2.75e-052183221940821
Pubmed

VWF propeptide and ratios between VWF, VWF propeptide, and FVIII in the characterization of type 1 von Willebrand disease.

VWF F8

2.75e-052183223349392
Pubmed

von Willebrand factor modulates immune complexes and the recall response against factor VIII in a murine hemophilia A model.

VWF F8

2.75e-052183237756521
Pubmed

Requirements for cellular co-trafficking of factor VIII and von Willebrand factor to Weibel-Palade bodies.

VWF F8

2.75e-052183217958741
Pubmed

STAT3 upregulates the protein expression and transcriptional activity of β-catenin in breast cancer.

STAT3 CTNNBIP1

2.75e-052183220830236
Pubmed

Von Willebrand and Factor VIII Portosystemic Circulation Gradient in Cirrhosis: Implications for Portal Vein Thrombosis.

VWF F8

2.75e-052183232032127
Pubmed

Anti-heavy-chain monoclonal antibodies directed to the acidic regions of the factor VIII molecule inhibit the binding of factor VIII to phospholipids and von Willebrand factor.

VWF F8

2.75e-052183212958606
Pubmed

Factor VIII antibody immune complexes modulate the humoral response to factor VIII in an epitope-dependent manner.

VWF F8

2.75e-052183237720212
Pubmed

Distinct roles of Ser-764 and Lys-773 at the N terminus of von Willebrand factor in complex assembly with coagulation factor VIII.

VWF F8

2.75e-052183223168412
Pubmed

Von Willebrand factor accelerates platelet adhesion and thrombus formation on a collagen surface in platelet-reduced blood under flow conditions.

VWF F8

2.75e-052183215459008
Pubmed

STAT3-EphA7 axis contributes to the progression of esophageal squamous cell carcinoma.

STAT3 EPHA7

2.75e-052183237738252
Pubmed

A novel B-domain O-glycoPEGylated FVIII (N8-GP) demonstrates full efficacy and prolonged effect in hemophilic mice models.

VWF F8

2.75e-052183223335368
Pubmed

Contributions of Asn2198, Met2199, and Phe2200 in the factor VIII C2 domain to cofactor activity, phospholipid-binding, and von Willebrand factor-binding.

VWF F8

2.75e-052183212719775
Pubmed

Factor VIII ectopically targeted to platelets is therapeutic in hemophilia A with high-titer inhibitory antibodies.

VWF F8

2.75e-052183216823491
Pubmed

IL-21 can supplement suboptimal Lck-independent MAPK activation in a STAT-3-dependent manner in human CD8(+) T cells.

STAT3 IL21

2.75e-052183222238455
Pubmed

Coagulation factor VIII regulates von Willebrand factor homeostasis invivo.

VWF F8

2.75e-052183237726033
Pubmed

A major determinant of the immunogenicity of factor VIII in a murine model is independent of its procoagulant function.

VWF F8

2.75e-052183222855607
Pubmed

Sources of variation in factor VIII, von Willebrand factor and fibrinogen measurements: implications for detecting deficiencies and increased plasma levels.

VWF F8

2.75e-052183220627205
Pubmed

Modifying murine von Willebrand factor A1 domain for in vivo assessment of human platelet therapies.

VWF ITGA2B

2.75e-052183218084279
Pubmed

Novel factor VIII variants with a modified furin cleavage site improve the efficacy of gene therapy for hemophilia A.

VWF F8

2.75e-052183227749002
Pubmed

von Willebrand factor and factor VIII are independently required to form stable occlusive thrombi in injured veins.

VWF F8

2.75e-052183217119108
Pubmed

Novel interactions between ERα-36 and STAT3 mediate breast cancer cell migration.

ESR1 STAT3

2.75e-052183231409371
Pubmed

Combined variants in factor VIII and prostaglandin synthase-1 amplify hemorrhage severity across three generations of descendants.

F8 PTGS1

2.75e-052183227629384
Pubmed

Recombinant factor VIII and factor VIII-von Willebrand factor complex do not present danger signals for human dendritic cells.

VWF F8

2.75e-052183216953272
Pubmed

Type 2N von Willebrand disease due to compound heterozygosity for R854Q and a novel R763G mutation at the cleavage site of von Willebrand factor propeptide.

VWF F8

2.75e-052183216953269
Pubmed

Thermodynamic analysis of the interaction of factor VIII with von Willebrand factor.

VWF F8

2.75e-052183222559004
Pubmed

Factor VIII deficiency not induced by FVIII gene mutation in a female first cousin of two brothers with haemophilia A.

VWF F8

2.75e-052183212406074
Pubmed

Von Willebrand Factor and Factor VIII levels in Egyptian children with newly diagnosed acute lymphoblastic leukemia in relation to peripheral blast cells and steroid therapy.

VWF F8

2.75e-052183225105915
Pubmed

The important role of von Willebrand factor in platelet-derived FVIII gene therapy for murine hemophilia A in the presence of inhibitory antibodies.

VWF F8

2.75e-052183225955153
Pubmed

Integrin-linked kinase is required for laminin-2-induced oligodendrocyte cell spreading and CNS myelination.

ILK LAMA2

2.75e-052183214581460
Pubmed

Life in the shadow of a dominant partner: the FVIII-VWF association and its clinical implications for hemophilia A.

VWF F8

2.75e-052183227587878
Pubmed

Simultaneous silencing of β-catenin and signal transducer and activator of transcription 3 synergistically induces apoptosis and inhibits cell proliferation in HepG2 liver cancer cells.

STAT3 CTNNBIP1

2.75e-052183225845340
Pubmed

Respiratory syncytial virus reduces STAT3 phosphorylation in human memory CD8 T cells stimulated with IL-21.

STAT3 IL21

2.75e-052183231780735
Pubmed

A genetic association study of circulating coagulation factor VIII and von Willebrand factor levels.

VWF F8

2.75e-052183238320121
Pubmed

Inflammation, hemostasis, and the risk of kidney function decline in the Atherosclerosis Risk in Communities (ARIC) Study.

VWF F8

2.75e-052183219110358
Pubmed

MYLK and PTGS1 Genetic Variations Associated with Osteoporosis and Benign Breast Tumors in Korean Women.

MYLK PTGS1

2.75e-052183233800915
Pubmed

von Willebrand factor binds to the surface of dendritic cells and modulates peptide presentation of factor VIII.

VWF F8

2.75e-052183226635035
Pubmed

K+-Driven Cl-/HCO3- Exchange Mediated by Slc4a8 and Slc4a10.

SLC4A8 SLC4A10

2.75e-052183238674160
Pubmed

Association of the factor VIII light chain with von Willebrand factor.

VWF F8

2.75e-05218323134349
Pubmed

CCAAT-displacement protein/cut homeobox transcription factor (CUX1) represses estrogen receptor-alpha (ER-α) in triple-negative breast cancer cells and can be antagonized by muscadine grape skin extract (MSKE).

ESR1 CUX1

2.75e-052183230964885
Pubmed

The defective interaction between von Willebrand factor and factor VIII in a patient with type 1 von Willebrand disease is caused by substitution of Arg19 and His54 in mature von Willebrand factor.

VWF F8

2.75e-05218328562925
Pubmed

The combination of IL-21 and IFN-alpha boosts STAT3 activation, cytotoxicity and experimental tumor therapy.

STAT3 IL21

2.75e-052183218947877
Pubmed

Factor VIII Is Synthesized in Human Endothelial Cells, Packaged in Weibel-Palade Bodies and Secreted Bound to ULVWF Strings.

VWF F8

2.75e-052183226473492
Pubmed

Rational design of a fully active, long-acting PEGylated factor VIII for hemophilia A treatment.

VWF F8

2.75e-052183220194895
Pubmed

Interaction between VWF and FVIII in treating VWD.

VWF F8

2.75e-052183225605439
Pubmed

Von Willebrand factor processing.

VWF F8

2.75e-052183228139814
Pubmed

Physiological Roles of the von Willebrand Factor-Factor VIII Interaction.

VWF F8

2.75e-052183232189311
Pubmed

Factor VIII binding affects the mechanical unraveling of the A2 domain of von Willebrand factor.

VWF F8

2.75e-052183232544272
Pubmed

Folate receptor-targeted RNAi nanoparticles for silencing STAT3 in tumor-associated macrophages and tumor cells.

ESR1 STAT3

2.75e-052183232084593
Pubmed

Selective inactivation of the Arg-Gly-Asp-Ser (RGDS) binding site in von Willebrand factor by site-directed mutagenesis.

VWF ITGA2B

2.75e-05218321737795
Pubmed

High levels of coagulation factors and venous thrombosis risk: strongest association for factor VIII and von Willebrand factor.

VWF F8

2.75e-052183230471183
Pubmed

The von Willebrand factor D'D3 assembly and structural principles for factor VIII binding and concatemer biogenesis.

VWF F8

2.75e-052183230642920
Pubmed

The D' domain of von Willebrand factor requires the presence of the D3 domain for optimal factor VIII binding.

VWF F8

2.75e-052183230111575
Pubmed

Heterogeneity and reciprocity of FVIII and VWF expression, and the response to shear stress in cultured human endothelial cells.

VWF F8

2.75e-052183235950488
Pubmed

Evaluation of von Willebrand factor phenotypes and genotypes in Hemophilia A patients with and without identified F8 mutations.

VWF F8

2.75e-052183225780857
Pubmed

Gene-centric approach identifies new and known loci for FVIII activity and VWF antigen levels in European Americans and African Americans.

VWF F8

2.75e-052183225779970
Pubmed

Autocrine IL-21 stimulation is involved in the maintenance of constitutive STAT3 activation in Sézary syndrome.

STAT3 IL21

2.75e-052183221938013
Pubmed

Necdin, a negative growth regulator, is a novel STAT3 target gene down-regulated in human cancer.

NDN STAT3

2.75e-052183222046235
Pubmed

Correlation between von Willebrand factor antigen, von Willebrand factor ristocetin cofactor activity and factor VIII activity in plasma.

VWF F8

2.75e-052183217786534
Pubmed

Abnormal von Willebrand factor secretion, factor VIII stabilization and thrombus dynamics in type 2N von Willebrand disease mice.

VWF F8

2.75e-052183228581694
Pubmed

Patterns of expression of factor VIII and von Willebrand factor by endothelial cell subsets in vivo.

VWF F8

2.75e-052183227207787
Pubmed

High factor VIII antigen levels increase the risk of venous thrombosis but are not associated with polymorphisms in the von Willebrand factor and factor VIII gene.

VWF F8

2.75e-052183211722428
Pubmed

B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans.

STAT3 IL21

2.75e-052183220048285
Pubmed

A new method measuring the interaction between von Willebrand factor and coagulation factor VIII.

VWF F8

2.75e-052183221094987
Pubmed

Chronic continuous hypoxia decreases the expression of SLC4A7 (NBCn1) and SLC4A10 (NCBE) in mouse brain.

SLC4A7 SLC4A10

2.75e-052183217928512
InteractionPDZK1 interactions

ASNSD1 ABCA1 SLC4A7 ESR1 SLC22A4 SLC26A6 KLHL17

1.87e-06661787int:PDZK1
InteractionIMMP1L interactions

ABCA1 ILK QRICH1 PTGS1 NDUFS8 MICU1 RINT1 MDN1 SLC22A4 GLS PCK2

1.15e-0524417811int:IMMP1L
Cytoband11p15.4

ILK MRGPRE OR51F1 OR51F2 GVINP1 OLFML1

1.61e-04200183611p15.4
GeneFamilyDyneins, axonemal

DNAH3 DNAH10 DNAH8 DNAH9

4.53e-06171234536
GeneFamilyCytochrome P450 family 27

CYP27C1 CYP27B1

1.37e-04312321014
GeneFamilySolute carriers

SLC4A7 SLC4A8 SLCO3A1 SLC7A14 SLC47A2 SLC22A4 SLC4A10 SLC49A3 SLC2A12 SLC26A6

3.70e-0439512310752
GeneFamilyZinc fingers SWIM-type|Mitogen-activated protein kinase kinase kinases

ZSWIM5 ZSWIM6

1.60e-039123290
GeneFamilyCyclic nucleotide gated channels

HCN4 HCN3

1.99e-03101232250
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

RALGAPA1 SMG1 RELCH SLC4A7 CHD2 LUC7L DDHD1 GLS HERC1

1.45e-071991839f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DNAH3 SLC4A8 DNAH10 HCN4 RIBC2 CFAP221 SLC22A4 DNAH9 HYDIN

1.45e-07199183915f7814b7074170eee7ccacaa670b1d128fc68bb
ToppCellLPS_IL1RA-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DNAH3 SLC4A8 DNAH10 HCN4 RIBC2 SLC47A2 CFAP221 DNAH9 HYDIN

1.51e-0720018394992dbf0514d674017315dbd20d91dfec0c608e9
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

HIVEP1 MRPS27 TMEM273 BORCS5 DDHD1 ENTPD1 COG4 SYMPK

9.37e-071831838807d64deaf4e50dccf6f831f88578a6d903c1421
ToppCellmegakaryocytic-Megakaryocyte|World / Lineage and Cell class

VWF ILK MYLK MAOB ITGA2B NAA38 PTGS1 TNNI3

1.06e-061861838acd15a169b6122b28cc99ef34de10701edcfedfe
ToppCellMegakaryocytic-erythropoietic-Megakaryo-cells-Megakaryocyte|World / Lineage, cell class and subclass

VWF ILK MYLK MAOB ITGA2B NAA38 PTGS1 TNNI3

1.40e-061931838352cd442b6e62f09b6d22a139774067873644594
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ILK MYLK LAMA2 HHIP NRXN3 MAGED2 CHP2 ENTPD1

1.51e-0619518382eed0332e338d6f0dbcb399d9d36c4611d491b0a
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_ACKR1+_endothelial_cells|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CTTNBP2 VWF MYLK MAOB CTSC RALGAPA2 PTGS1 ENTPD1

1.63e-061971838143607d195c8aa2b94d995af0b2ef38582565611
ToppCell5'-Adult-SmallIntestine-Epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC4A7 MAOB AQP11 AGPAT2 CLDN7 CHP2 ALDH1A1 PCK2

1.69e-0619818388d629492d2199de8e036c19e9dacceb9c9e721a0
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF21B SLC4A8 MRGPRE MATN4 GUCY1B2 CACNG4 NUDCD1

5.33e-0616418370853e75b60b2a78257b660910c3ee15b09c5f5b0
ToppCell356C-Fibroblasts-Fibroblast-D|356C / Donor, Lineage, Cell class and subclass (all cells)

EVC2 FBXL14 PCDHB4 LAMA2 OLFML1 AMOT SCN7A

5.78e-0616618377286a37b2827f3747469ffd0d76cbe81116db7ee
ToppCell356C-Fibroblasts-Fibroblast-D-|356C / Donor, Lineage, Cell class and subclass (all cells)

EVC2 FBXL14 PCDHB4 LAMA2 OLFML1 AMOT SCN7A

5.78e-0616618377c2eee0a4f45795a956acf936b85bdb35f1b1624
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DNAH10 HCN4 CFAP221 LMLN DNAH9 HYDIN

6.50e-061691837fba841664939c771881ba97f14ef1df6635c04ff
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VWF MRGPRE OBSCN PCDHB4 MSN FICD ENTPD1

7.29e-0617218379a1743abcd5fbd38253ea84d88ad716cfb71de36
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYLK FBXL14 HHIP GPR156 FAM118A CALN1 CNDP1

7.86e-0617418377fb7bdf62563f2102fb38618b503eb2817b6594f
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 SLC4A7 HCN4 F8 HSPA13 HERC1 SLC2A12

9.12e-061781837fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

RALGAPA1 SMG1 CHD2 BORCS5 DDHD1 GLS HERC1

1.02e-051811837f2315414e714ac86211546a935660c4be6e85f1b
ToppCellfacs-Skin-Telogen-3m-Epithelial-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTTNBP2 CWH43 MAOB SLCO3A1 PTGS1 SLC22A4 CUX1

1.09e-05183183726b18d1cc5d98f185176e100bafb9bc9081c66f7
ToppCellCOVID-19-Heart-EC_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

VWF RALGAPA2 F8 TMEM273 SV2B ENTPD1 TBCD

1.09e-051831837ff95382cfed592190d0636d2b750328471f82e0d
ToppCellEndothelial-Endothelial-E|Endothelial / shred on cell class and cell subclass (v4)

VWF NDN ITPRID2 PTGS1 HHIP NRXN3 ENTPD1

1.30e-0518818372777eb7689b271c199021fe7d9db88ccebff14de
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDE4C ZSWIM5 SLCO3A1 NDN MAGED2 ENTPD1 ALDH1A1

1.49e-0519218378ad6678df89175c5a4a835c8566f1552df3c996e
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAH3 DNAH10 CFAP221 SLC22A4 ALDH3B1 DNAH9 HYDIN

1.49e-051921837be592e661367affced9ebe80849b466e6adb3a34
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

RALGAPA1 SMG1 CHD2 STAT3 LUC7L GLS HERC1

1.49e-05192183747646d7e4990be85072987f92bf18d52f8da752e
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDE4C ZSWIM5 SLCO3A1 NDN MAGED2 ENTPD1 ALDH1A1

1.49e-0519218372f5378ea0b2fb2f672a36585d375f675983363a1
ToppCellfacs-Heart-RV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOB LAMA2 NDN MAGED2 OLFML1 SCN7A ALDH1A1

1.54e-051931837735a72fac16397edde95e8eefa6f83caeb5ee5df
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAH3 DNAH10 CFAP221 SLC22A4 ALDH3B1 DNAH9 HYDIN

1.54e-0519318370b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCellfacs-Heart-RV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOB LAMA2 NDN MAGED2 OLFML1 SCN7A ALDH1A1

1.54e-051931837ff901d2f3d7a511639c1e3b76058896c0d8a8602
ToppCellwk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

DNAH3 DNAH10 CFAP221 SLC22A4 ALDH3B1 DNAH9 HYDIN

1.59e-051941837756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCell10x3'2.3-week_14-16-Hematopoietic-MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ILK MYLK ITGA2B NAA38 PTGS1 MAGED2 TNNI3

1.59e-051941837216cba1a04b1a24b080322bc950e7fa2dade5ff1
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DNAH10 RIBC2 CFAP221 ALDH3B1 DNAH9 HYDIN

1.65e-051951837649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DNAH10 RIBC2 CFAP221 ALDH3B1 DNAH9 HYDIN

1.65e-051951837129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DNAH10 RIBC2 CFAP221 ALDH3B1 DNAH9 HYDIN

1.65e-0519518373e70ee987d66d450062d5df3d7c733ccc7344470
ToppCellCOVID-19-Epithelial-Ciliated_cells|Epithelial / Condition, Lineage and Cell class

DNAH3 DNAH10 RIBC2 CFAP221 ALDH3B1 DNAH9 HYDIN

1.70e-051961837de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 DNAH10 RIBC2 CFAP221 SLC22A4 DNAH9 HYDIN

1.76e-0519718376865f4831eb23794fb88a8649d48d497bbae3f44
ToppCellControl_saline-Epithelial_alveolar-AT_2|Control_saline / Treatment groups by lineage, cell group, cell type

CTSC CLDN7 PEBP4 GXYLT2 HHIP NRXN3 ABCD3

1.76e-051971837b8f62fcd6eb8f47b3cc41f616126f82c68a36e87
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 DNAH10 RIBC2 CFAP221 SLC22A4 DNAH9 HYDIN

1.82e-051981837ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DNAH3 DNAH10 CFAP221 SLC22A4 ALDH3B1 DNAH9 HYDIN

1.94e-0520018377cb3e3bd9e851ccb096e0a3471819471d85ebace
ToppCellParenchymal-10x3prime_v2-Epithelial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ANKRD29 CLDN7 PEBP4 HHIP CFAP221 ALDH3B1 RNF145

1.94e-05200183716828c6a2be66bbbd805453325d6da719f2dea1b
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DNAH3 DNAH10 CFAP221 SLC22A4 ALDH3B1 DNAH9 HYDIN

1.94e-0520018378441e289377215a6877640946fe3f6de1f456502
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

VWF ITGA2B PTGS1 HHIP FICD SLC22A4

2.92e-0514418363d880c140db4a0e7602bfddcb73a42a68c2848d5
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH3 DNAH10 RIBC2 CFAP221 DNAH9 HYDIN

3.41e-051481836d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH3 DNAH10 RIBC2 CFAP221 DNAH9 HYDIN

3.41e-051481836c8e93b87212f55774223caa385859c566fa1981f
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Tnc|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MAOB DNAH10 HCN4 SLC22A4 SCN7A ALDH3B1

4.25e-0515418360066b2b8cfc74603e97f271ef5efc7ec512110dc
ToppCellControl-Epithelial_airway-Ciliated_cells-Ciliated|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH3 DNAH10 RIBC2 CFAP221 DNAH9 HYDIN

4.25e-0515418364e3bc24043144143842627cacf6f90dda2228910
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH3 DNAH10 RIBC2 CFAP221 DNAH9 HYDIN

4.25e-0515418369ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellControl-Epithelial_airway-Ciliated_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH3 DNAH10 RIBC2 CFAP221 DNAH9 HYDIN

4.25e-0515418367556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH3 DNAH10 RIBC2 CFAP221 DNAH9 HYDIN

4.25e-05154183658072ce422d09f2de602580325eaac6c4ec6c136
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

RALGAPA1 SMG1 STAT3 GLS HERC1 FAM118A

4.57e-0515618361545169694f686d28648a68b552c2ae606599d66
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

DNAH3 NRXN3 SLC4A10 DNAH8 DNAH9 CALN1

5.08e-0515918365335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTTNBP2 DNAH10 LAMA2 RXFP2 DNAH9 HYDIN

5.26e-051601836c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

PDE4C APBA2 ZSWIM6 RALGAPA2 NUDCD1 KLHL17

5.26e-0516018368aaf6ac4f33ea291387fdbf9ff1a91d559391774
ToppCellPBMC-Severe-cDC_4|Severe / Compartment, Disease Groups and Clusters

KIF21B SLC4A8 DNAH10 ITGA2B GOSR2 GUCY2D

5.26e-0516018364dac64e58d9366c399f3d830848ccb720d400be7
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTTNBP2 DNAH10 LAMA2 RXFP2 DNAH9 HYDIN

5.26e-05160183625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic-Mast_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA1 CTTNBP2 HSPA13 SLC4A10 CACNG4 RNF145

5.45e-051611836c54010d88f1ecb6e0235bb66084876a4d5bf1ecd
ToppCellBL-critical-LOC-Myeloid-Basophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KIF21B CTTNBP2 MAOB PTGS1 CATSPER2 DNAH8

5.64e-05162183625ec9df914445b4daae4fd28fd0e60b64797c46d
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

RALGAPA1 SMG1 CHD2 STAT3 BORCS5 DDHD1

5.64e-051621836b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDE4C SLC4A8 CTSC MATN4 CLDN7 MAGED2

5.84e-05163183622fa5d017ff796394394d952ec151e2d1beb8248
ToppCellMild-Myeloid-Mast|Mild / Condition, Lineage, Cell class and cell subclass

CTTNBP2 VWF MAOB PTGS1 PEBP4 PKMYT1

6.24e-0516518365fa9552c37890c5cc7e672a47038aebba2413cb4
ToppCellMild-Myeloid-Mast-|Mild / Condition, Lineage, Cell class and cell subclass

CTTNBP2 VWF MAOB PTGS1 PEBP4 PKMYT1

6.24e-05165183693d3909a0f5f43d473d5005c842d7d73e25eceed
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-Enterocyte_(Proximal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AGPAT2 PPFIA3 CHP2 SLC49A3 ALDH1A1 CHP1

6.46e-05166183622b31acbbef1936ce19b393cf880c63ea2fa0f1b
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VWF CACHD1 ITPRID2 PTGS1 PPM1L SLC4A10

6.68e-051671836f01b96173deda0239fa482989873cf308e49d48c
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VWF CACHD1 ITPRID2 PTGS1 PPM1L SLC4A10

6.68e-0516718365fc85a05124cd2324e1b8ff940193880f83cd8af
ToppCellfacs-Lung-nan-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF MRGPRE MYOZ3 RALGAPA2 PTGS1 CUX1

7.37e-0517018368e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCellfacs-Lung-nan-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF MRGPRE MYOZ3 RALGAPA2 PTGS1 CUX1

7.37e-05170183667d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VWF OBSCN PCDHB4 MSN GXYLT2 ENTPD1

7.37e-051701836af8b56555cbd5a1016ab9ec2ce88225c58c89648
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Enterocyte_(Proximal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITPRID2 PPFIA3 CYTIP CHP2 ALDH1A1 CHP1

7.61e-0517118365d0d6c1ff610a703ae0b834a12823c5ff9012932
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

RALGAPA1 SMG1 CHD2 STAT3 GLS HERC1

7.61e-0517118362e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellE12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

VWF ITGA2B STARD9 SLC2A12 OPLAH TANGO6

7.86e-0517218363b9be685fcd1634498a603b692f5ac6ddd0de176
ToppCellASK454-Epithelial-Transformed_epithelium|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

ZSWIM5 CLDN7 POP1 CACNG4 ALDH3B1 SYMPK

7.86e-0517218363986f0f098ef5e096c8d9ee3d335b8404083701f
ToppCell10x5'-GI_small-bowel-Mast|GI_small-bowel / Manually curated celltypes from each tissue

CTTNBP2 MAOB MYOZ3 PTGS1 SCN7A ALDH3B1

8.37e-051741836e94c980b25edfd0e8598c416828801fcc00e8ead
ToppCell10x5'-GI_small-bowel-Mast-Mast_cells|GI_small-bowel / Manually curated celltypes from each tissue

CTTNBP2 MAOB MYOZ3 PTGS1 SCN7A ALDH3B1

8.37e-05174183605525bf0a2bde2be4f7c147b17a24530ce8819e0
ToppCellHealthy_Control-Myeloid-Mast|Healthy_Control / Condition, Lineage, Cell class and cell subclass

CTTNBP2 MAOB AQP11 OBSCN HHIP SCN7A

8.64e-051751836ca187074adcc9b8bd0fa270e2ede1564c8e6c6cf
ToppCellHealthy_Control-Myeloid-Mast-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

CTTNBP2 MAOB AQP11 OBSCN HHIP SCN7A

8.64e-051751836eadbbcdf2aef4cee268bc70a7a2c4175d898953b
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDE4C MICU1 GXYLT2 NRXN3 HHAT SLC26A6

9.20e-051771836a235ff4f37a7622216526191efc4832fb8ed6957
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 NDN ST8SIA3 NRXN3 SV2B GLS

9.20e-0517718361dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCell10x5'-GI_large-bowel-Mast|GI_large-bowel / Manually curated celltypes from each tissue

ABCA1 CTTNBP2 MAOB PTGS1 SCN7A ALDH1A1

9.49e-051781836d10ed2543c96e1a2373f847e0b82144771e26d07
ToppCell10x5'-GI_large-bowel-Mast-Mast_cells|GI_large-bowel / Manually curated celltypes from each tissue

ABCA1 CTTNBP2 MAOB PTGS1 SCN7A ALDH1A1

9.49e-0517818368fc5f735afa25ae43c2acb1c710ade6e9e093e3c
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_Erythro-Mega|lymph-node_spleen / Manually curated celltypes from each tissue

VWF MYLK MAOB ITGA2B PTGS1 TNNI3

9.78e-0517918364e0cf069bc47328eda753a4edc7e89b8915d52bb
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DNAH10 SLC7A14 CFAP221 SLC22A4 DNAH9

9.78e-0517918365e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VWF ZSWIM6 PPFIA3 PKMYT1 ENTPD1 TANGO6

1.01e-04180183640d4838a0ccb10d5e49266bc8a0037d27b75ccc2
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC4A8 DNAH10 PTGS1 DENND4B SLC49A3 ALDH1A1

1.04e-041811836338c7362d258a87f1a6b1a65376f5394d4b2b4b2
ToppCell3'_v3-blood-Hematopoietic_Erythro-Mega|blood / Manually curated celltypes from each tissue

VWF MYLK MAOB ITGA2B PTGS1 TNNI3

1.07e-0418218363100165c5ba8c3016f9a2f7a8e4ea136750823fe
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast|PND01-03-samps / Age Group, Lineage, Cell class and subclass

LAMA2 HHIP OLFML1 HHAT CACNA1G GPRASP2

1.07e-041821836812dac35b9aa05be48258082e007f6c00e7b4dd8
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THEMIS2 CYTIP TMEM273 AMOT ALDH3B1 DHX34

1.07e-04182183657f8b8d7b132f3ad6f2b1e79c3812fe938657d2c
ToppCellfacs-Skin-Telogen-3m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTTNBP2 MAOB SLCO3A1 PTGS1 MICU1 CUX1

1.10e-041831836ed1e0b07475f9951728682ed70b85367cf2a744d
ToppCell10x3'2.3-week_17-19-Hematopoietic-MK-MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ILK MYLK ITGA2B NAA38 PTGS1 TNNI3

1.14e-041841836ba65e3972b2b8d825a2c1a9d03d092cc1afad073
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_Erythro-Mega-Megakaryocyte_early|lymph-node_spleen / Manually curated celltypes from each tissue

VWF MYLK MAOB ITGA2B PTGS1 TNNI3

1.14e-04184183610607d7d92edcbb92d992900086b90b307421cc3
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic-mast_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ABCA1 CTTNBP2 MAOB PTGS1 TMEM273 ALDH1A1

1.17e-0418518363fafb1d36c5f98a29d20a5ce5192c83d6f603514
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTTNBP2 DNAH10 APBA2 F8 MDN1 CHP2

1.17e-041851836bb5a4cf93534b9bcd0923f314c389d571e91e7f8
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 DNAH10 RIBC2 CFAP221 DNAH9 HYDIN

1.21e-04186183676033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 DNAH10 RIBC2 CFAP221 DNAH9 HYDIN

1.21e-04186183685787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCellILEUM-inflamed-(8)_Fibroblast-(8)_Smooth_muscle_cells|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

MYLK ITPRID2 HHIP DDHD1 SCN7A HYDIN

1.21e-041861836cacc2f0b2ed46516173b61ba1c5c226a2db7cddc
ToppCellPND14-Epithelial-Epithelial_Airway|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNAH3 CLDN7 ALDH1A1 ALDH3B1 DNAH9 HYDIN

1.24e-0418718361399c703505211c510b3f14c7a2aa9930566c473
ToppCellpdx-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

SLC4A8 CTSC CACHD1 GXYLT2 NRXN3 CFAP221

1.24e-0418718367e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell21-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

MAOB DNAH10 CFAP221 ALDH3B1 DNAH9 HYDIN

1.24e-0418718361a2178a195d078d1963947b327c6d0d4f2f48341
ToppCellControl-Endothelial-VE_Peribronchial|Endothelial / Disease state, Lineage and Cell class

ANKRD29 SLC4A7 VWF RIBC2 CACHD1 SLC22A4

1.24e-0418718365429ae85942b8ec3895cceb63c663de3c24ca064
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

RALGAPA1 SMG1 CHD2 DDHD1 GLS HERC1

1.28e-041881836ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellEpithelial-Epithelial-D_(Ciliated)|Epithelial / shred on cell class and cell subclass (v4)

DNAH3 DNAH10 ALDH1A1 ALDH3B1 DNAH9 HYDIN

1.28e-0418818368f30535a32968a81a304315a49c0d90a77d36948
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CTSC MATN4 CLDN7 PTGS1 ABCD3 EPHA7

1.28e-0418818367499e353ea5853d06558b20cedee3c7910425d7d
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CTSC MATN4 CLDN7 PTGS1 ABCD3 EPHA7

1.28e-041881836562f5984efdbbcb8f53ddcee033ccbf9eb678425
ComputationalOxidoreductases.

MAOB ALDH1A1 ALDH3B1 GOT2

7.32e-05221134MODULE_373
DiseaseProfound Mental Retardation

KDM5A ENTPD1 SLC4A10 CACNA1G ARL14EP TBCD CNDP1

2.18e-051391777C0020796
DiseaseMental Retardation, Psychosocial

KDM5A ENTPD1 SLC4A10 CACNA1G ARL14EP TBCD CNDP1

2.18e-051391777C0025363
DiseaseMental deficiency

KDM5A ENTPD1 SLC4A10 CACNA1G ARL14EP TBCD CNDP1

2.18e-051391777C0917816
Diseasevon Willebrand's disease 2 (is_marker_for)

VWF F8

3.58e-0521772DOID:0060574 (is_marker_for)
Diseaselymphangioleiomyomatosis (is_marker_for)

ESR1 STAT3 GLS

4.49e-05121773DOID:3319 (is_marker_for)
Diseaseanemia (implicated_via_orthology)

SLC4A7 SLC4A8 SLC4A10

9.16e-05151773DOID:2355 (implicated_via_orthology)
Diseasevon Willebrand's disease 1 (is_implicated_in)

VWF ITGA2B

2.13e-0441772DOID:0060573 (is_implicated_in)
DiseaseIntellectual Disability

RALGAPA1 KDM5A QRICH1 ENTPD1 SLC4A10 CACNA1G ARL14EP GOT2 TBCD CNDP1

3.91e-0444717710C3714756
Diseaseright ventricular ejection fraction measurement

ABCA1 OBSCN GOSR2

7.65e-04301773EFO_0021816
DiseaseColorectal Carcinoma

RELCH DNAH3 ABCA1 EVC2 OBSCN TYMP NT5C HHIP ABCD3 DNAH8 CUX1 EPHA7

1.14e-0370217712C0009402
DiseaseKartagener Syndrome

CFAP221 DNAH9 HYDIN

1.21e-03351773C0022521
DiseaseCiliary Dyskinesia, Primary, 1, With Or Without Situs Inversus

CFAP221 DNAH9 HYDIN

1.21e-03351773C4551906
DiseasePolynesian Bronchiectasis

CFAP221 DNAH9 HYDIN

1.21e-03351773C4317124
Diseaseectonucleoside triphosphate diphosphohydrolase 1 measurement

MED16 ENTPD1

1.25e-0391772EFO_0020342
DiseaseSitus ambiguous

PKD1L1 DNAH9

1.25e-0391772C1167664
DiseaseAutism Spectrum Disorders

CTTNBP2 CHD2 NRXN3 DDHD1

1.74e-03851774C1510586
Diseaseearly infantile epileptic encephalopathy (implicated_via_orthology)

UFSP2 GOT2

1.90e-03111772DOID:0050709 (implicated_via_orthology)
Diseasecryptorchidism (biomarker_via_orthology)

KDM5A ESR1

1.90e-03111772DOID:11383 (biomarker_via_orthology)
DiseaseSitus Inversus

PKD1L1 DNAH9

1.90e-03111772C0037221
Diseasequality of life during menstruation measurement, acne

NLN CALN1

1.90e-03111772EFO_0003894, EFO_0009366
Diseaseobesity (implicated_via_orthology)

DNAH10 ESR1 PNPLA5 STAT3 ALDH1A1 GNRHR

1.95e-032151776DOID:9970 (implicated_via_orthology)
Diseaseplatelet component distribution width

THEMIS2 EEFSEC SLC4A7 VWF ITGA2B TMEM273 CTNNBIP1 DDHD1 ENTPD1 HERC1 RNF145 CUX1

2.10e-0375517712EFO_0007984
Diseasephenylacetylglutamine measurement

SV2B RXFP2

2.27e-03121772EFO_0021013
DiseaseADHD symptom measurement

PCK2 CUX1

2.27e-03121772EFO_0007860
Diseasesocial interaction measurement

HIVEP1 CTTNBP2 SLC4A10 GNRHR

2.51e-03941774EFO_0009592
DiseaseParoxysmal atrial fibrillation

VWF DNAH10 HCN4 GOSR2 HERC1

2.56e-031561775C0235480
Diseasefamilial atrial fibrillation

VWF DNAH10 HCN4 GOSR2 HERC1

2.56e-031561775C3468561
DiseasePersistent atrial fibrillation

VWF DNAH10 HCN4 GOSR2 HERC1

2.56e-031561775C2585653
Diseasedimethylglycine measurement

RAD18 UFSP2 CACNA1G

2.67e-03461773EFO_0010476
Diseaseimidazole lactate measurement

CNOT1 GOT2

2.67e-03131772EFO_0800004
DiseasePrimary Ciliary Dyskinesia

CFAP221 DNAH9 HYDIN

2.83e-03471773C4551720
DiseaseAtrial Fibrillation

VWF DNAH10 HCN4 GOSR2 HERC1

2.85e-031601775C0004238
DiseaseCarcinomatosis

ESR1 NDN TYMP PTGS1 STAT3

3.09e-031631775C0205699
DiseaseCarcinoma, Spindle-Cell

ESR1 NDN TYMP PTGS1 STAT3

3.09e-031631775C0205697
DiseaseUndifferentiated carcinoma

ESR1 NDN TYMP PTGS1 STAT3

3.09e-031631775C0205698
DiseaseAnaplastic carcinoma

ESR1 NDN TYMP PTGS1 STAT3

3.09e-031631775C0205696
DiseaseCarcinoma

ESR1 NDN TYMP PTGS1 STAT3

3.17e-031641775C0007097
DiseaseSitus ambiguus

PKD1L1 DNAH9

3.57e-03151772C0266642
DiseaseN-acetylmethionine measurement

SLCO3A1 EPHA7

3.57e-03151772EFO_0021427
DiseaseJT interval

SLC4A7 OBSCN STAT3 SLC2A12 CNOT1 CUX1

3.95e-032481776EFO_0007885
DiseaseSchizoaffective disorder-bipolar type

PKMYT1 NRXN3

4.06e-03161772EFO_0009965
Disease5-oxoproline measurement

DNAH8 OPLAH

4.06e-03161772EFO_0010988
DiseaseFamilial Progressive Myoclonic Epilepsy

CHD2 GOSR2

4.59e-03171772C0751777
DiseaseAtypical Inclusion-Body Disease

CHD2 GOSR2

4.59e-03171772C0751776
DiseaseMyoclonic Epilepsies, Progressive

CHD2 GOSR2

4.59e-03171772C0751778
DiseaseBiotin-Responsive Encephalopathy

CHD2 GOSR2

4.59e-03171772C0751780
DiseaseMay-White Syndrome

CHD2 GOSR2

4.59e-03171772C0751782
DiseaseDentatorubral-Pallidoluysian Atrophy

CHD2 GOSR2

4.59e-03171772C0751781
DiseaseAction Myoclonus-Renal Failure Syndrome

CHD2 GOSR2

5.14e-03181772C0751779
DiseaseAtherosclerosis

ABCA1 ESR1 STAT3

5.39e-03591773C0004153
DiseaseAtherogenesis

ABCA1 ESR1 STAT3

5.39e-03591773C1563937
DiseaseMalignant neoplasm of breast

THEMIS2 ANKRD29 VWF RIBC2 ZSWIM5 ESR1 OBSCN LAMA2 PTGS1 STAT3 MAGED2 POP1 DNAH9 CUX1

5.48e-03107417714C0006142
Diseasebody surface area

RALGAPA1 PDE4C HIVEP1 ESR1 HHIP NRXN3 GPR156 ZNF844 CALN1 SYMPK

5.64e-0364317710EFO_0022196
DiseasePhenyllactate (PLA) measurement

CNOT1 GOT2

5.72e-03191772EFO_0021662
Diseasebipolar disorder (is_marker_for)

VWF PTGS1

5.72e-03191772DOID:3312 (is_marker_for)
DiseaseUsual Interstitial Pneumonia

ESR1 STAT3

5.72e-03191772C4721509
DiseaseHamman-Rich Disease

ESR1 STAT3

5.72e-03191772C4721508
Diseasesensorineural hearing loss (implicated_via_orthology)

SLC7A14 DNAH9

5.72e-03191772DOID:10003 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
RILGYRSTMELVLDM

TDRD5

46

Q8NAT2
RMIDIQTRMAGRALE

BUD23

31

O43709
VRSLSERLMQMSLAT

AMOT

171

Q4VCS5
MALIFRTAMQSVGLL

CLDN24

1

A6NM45
MQTSAMALLARILRA

CYP27C1

1

Q4G0S4
LLGSIIFRSIIVAMM

CATSPER2

326

Q96P56
LLMVLGTDMSDRRAA

COG4

251

Q9H9E3
SNDMLLLQLRTGMTL

ARL14EP

36

Q8N8R7
QSPRRLRMLLVAMEA

ALDH3B1

446

P43353
RILMTATQESRGNIM

GVINP1

1696

Q7Z2Y8
RLKETMRIMGLDNSI

ABCA1

666

O95477
SQMGHSEVVRVMLLR

ANKRD29

186

Q8N6D5
QMRRLAAEELGVVTM

CACHD1

51

Q5VU97
IERDRLLLATMESMN

ALDH1A1

96

P00352
REMRDLLMNLGQEIT

GLE1

316

Q53GS7
ADIGNIVVLMARRRM

APBA2

461

Q99767
SVMLIAANQILRSGM

CALN1

246

Q9BXU9
CMRTVGLAERALQIM

ACAD11

636

Q709F0
MARSVRVLVDMDGVL

NT5C

1

Q8TCD5
RLMDNFLIREMSGST

RAD18

131

Q9NS91
SREQMGQMLTRILVI

QRICH1

746

Q2TAL8
MLRLTLQTTSDGVML

GLS

181

O94925
SKDNMRTRIMIGLTL

SLC2A12

271

Q8TD20
LGRIMNLTVMLDTAL

NUDCD1

81

Q96RS6
VVMSRGICMRLIVLS

OR5I1

136

Q13606
MRNQMITRVPLGSVI

MAOB

281

P27338
MGRRLAELELQMALA

CYP27B1

456

O15528
RIADSEKSVMLMLGR

RELCH

511

Q9P260
RMFELTLRGMSEALV

RELCH

986

Q9P260
LATMLGNTGMILLIR

OR9Q2

36

Q8NGE9
MVGAMRLAVTNEERL

FAM189A1

511

O60320
AVRAIGRLSSMAMIS

MYLK

1751

Q15746
TEGMRRLAMLVGRAL

MDN1

1366

Q9NU22
ETMRQFLMGLLRGLN

MATN4

51

O95460
LLMVLLSIIFMNGNR

MAGED2

371

Q9UNF1
QMRALLDQLMGTARD

LUC7L

6

Q9NQ29
DNSRALIQRMGMTVI

NLRC4

6

Q9NPP4
GRKTNIIDSMLRMLE

GUCY2D

811

Q02846
GELERLMVTMLTERE

PPFIA3

26

O75145
RTSRLLMNLILMQAG

FICD

371

Q9BVA6
AQVLLARTMVMRALS

HERC1

3181

Q15751
RITLALMEDTGRQML

LMLN

401

Q96KR4
SMGRLVLSNKMARTI

CUX1

606

Q13948
IMEMLRLKGRERAST

KCNV1

476

Q6PIU1
RRLMMVAFLGASAVT

MICU1

31

Q9BPX6
ASMRIMTRLGTPVLQ

PCK2

186

Q16822
SMMGLLTNLADRELV

ESR1

341

P03372
TNSRIIQMGLLMITR

OR51F1

146

A6NGY5
TNARIAKIGMSMLIR

OR51F2

151

Q8NH61
LSLRRMVIDMVLATD

PDE4C

486

Q08493
RLVTAALLLGLMMVV

PEBP4

6

Q96S96
DSELSIVMRGLRDMN

DNAH8

2041

Q96JB1
SALRAEIARLQMELM

KIF21B

386

O75037
VNSGVMLMNLTRIRS

GXYLT2

266

A0PJZ3
FLMVSRDRLRTVLML

NRXN3

111

Q9Y4C0
MAMVPGATLRRLLSV

EVC2

1131

Q86UK5
MAELTARISQLEMAR

MSN

421

P26038
LDIANMLGLSNTVMR

GOSR2

166

O14653
LLLGDLARLEQMVMS

LAMA2

1581

P24043
LARLEQMVMSINLTG

LAMA2

1586

P24043
SIRSTLRMELMGCDL

F8

2176

P00451
TLVIAMSLQLDRRGM

PGAP6

641

Q9HCN3
TRITMKRMAQLLDLS

PSMD12

371

O00232
FIREMLMRLVLTVRS

PTGS1

106

P23219
TAGMRLLRMESEELA

ENTPD1

131

P49961
SAVVRIFNLIGMMLL

HCN3

246

Q9P1Z3
TMCGASLMLLLRVER

MRGPRE

191

Q86SM8
MGSQTMAVALPRDLR

RIBC2

1

Q9H4K1
RSLELIPLTARMVMA

RALGAPA2

1366

Q2PPJ7
ARMTIEDVMSLGITL

EPHA7

956

Q15375
GINRMVRQMHGLRTL

FBXL14

321

Q8N1E6
RSLNLFRTQMMDLEL

ITPRID2

966

P28290
ETRLRESVVQMGVLM

KDM5A

646

P29375
QLMMRTRIAAQGFTV

HIGD2A

76

Q9BW72
LASAVVRIVNLIGMM

HCN4

411

Q9Y3Q4
MMVALRGASALLVLF

OLFML1

1

Q6UWY5
LRDGTSLGMLRELMV

MED16

646

Q9Y2X0
MRCLTTPMLLRALAQ

NDUFS8

1

O00217
MSLEGQMAELRILRL

OBSCN

2516

Q5VST9
RSGTVMVRILIMDIN

PCDHB4

221

Q9Y5E5
LGHMVVSQMATLLAR

HHAT

76

Q5VTY9
IISDLTMEMNRFRLI

POP1

421

Q99575
MRGATRVSIMLLLVT

PROK1

1

P58294
LKERLNMTLGLMRGT

CCDC105

346

Q8IYK2
NMTLGLMRGTILRCT

CCDC105

351

Q8IYK2
LQSILSLMDRGAMVL

FAM118A

131

Q9NWS6
TRRILMMNTGDVGAR

HYDIN

4546

Q4G0P3
AMSRMRQRGLLCDIV

KLHL17

81

Q6TDP4
MMVVISLDRSLAITR

GNRHR

131

P30968
GRGIMIAILVNTLSM

CACNA1G

746

O43497
AVGMRALLDTVMQAL

CACNA1G

1726

O43497
MVRCDRGLQMLLTTA

CACNG4

1

Q9UBN1
TRLDIVDMLLVTAMG

DNAH3

2176

Q8TD57
RGNRVLIFSQMVRML

CHD2

806

O14647
LRMLLSVMEGELEAR

CTTNBP2

41

Q8WZ74
MRSSPGNMERIVICL

IL21

1

Q9HBE4
RSAVVEMLIMRGARI

ILK

46

Q13418
EMSAILRRIQMGIDQ

BORCS5

151

Q969J3
FASMGMLEARIRILT

CTSC

261

P53634
TGSLTMDDNRRIQML

CYTIP

31

O60759
EALLNKTMRIRMTDG

NAA38

46

Q9BRA0
EIMMELGRISSRNLG

ASNSD1

521

Q9NWL6
LSVRVMLEMRQAGIV

DENND4B

831

O75064
METLIQTRLSMLCIG

GPR156

116

Q8NFN8
MAREMTILGSAVLTL

HSPA13

1

P48723
VRGLRDMLNSSAMDI

DDHD1

476

Q8NEL9
RLMARQRPVMLVGTA

DNAH9

2466

Q9NYC9
RRVALDSLVLQMKSM

DHX34

521

Q14147
LMKRLRNIMDTLTFS

DNAH10

3696

Q8IVF4
MSMILSASVIRVRDG

SEC22A

1

Q96IW7
DLFRTRNIAIMTIMS

SLC22A4

331

Q9H015
EMIGSVLMLRDLVSF

PKD1L1

1366

Q8TDX9
TVMADLGERMVRENL

AGPAT2

151

O15120
MGMSNLTRLSEFILL

OR1L3

1

Q8NH93
VMIQGRLFNMLSAVR

CFAP221

471

Q4G0U5
RERSDVLLGTMMLII

CWH43

346

Q9H720
MAASIVRRGMLLARQ

MRPS27

1

Q92552
MLESVMAELTLLRTR

RTL6

56

Q6ICC9
MGVSRLMDLLADSRE

USO1

166

O60763
REQRVTGLMIFILMG

SLC4A7

1006

Q9Y6M7
MRGLQLLVDLVTSMD

PLCD4

116

Q9BRC7
GILLTFVVRMRIMGL

SLC47A2

456

Q86VL8
SALGAIRMAMLVNLV

SLCO3A1

416

Q9UIG8
MDSLRGQTDLMAERL

SV2B

71

Q7L1I2
VNLKGMLRQLSDMRS

SLC26A6

451

Q9BXS9
MSIAEQMGRILQRTA

OPLAH

746

O14841
MQGLLRNMALEVFSR

PNPLA5

376

Q7Z6Z6
QLTGIRMLRHLTMTI

GPRASP2

696

Q96D09
TDDMIVMATLRLLRL

SMG1

1781

Q96Q15
RMLRTLGGNLMEFIE

GUCY1B2

6

O75343
MIEDTMTLLSLLGRI

PPM1L

1

Q5SGD2
MARVASVLGLVMLSV

ST8SIA3

6

O43173
RLMGFLAMLSTEVSV

RXFP2

496

Q8WXD0
DQTRIRFMLETMLAL

NOM1

541

Q5C9Z4
MTLELLQSTRIGMSV

TCEA1

36

P23193
REQRVTGLMIFVLMG

SLC4A8

876

Q2Y0W8
EMARLIRSVMQLENG

STARD9

2046

Q9P2P6
MARGQRAMVTVLAFL

ITGA2B

926

P08514
RDRRMMSQLELLSGG

HHIP

51

Q96QV1
GDILRLLDRDRMMQT

URB1

1591

O60287
ESVMMFGRNLRQLLL

SRBD1

516

Q8N5C6
GRMLLRMSQALGRIV

ABCD3

361

P28288
MTRLAGFTARITELM

ABCD3

381

P28288
VMADRIIGMRTQLVS

GOT2

346

P00505
MLSVVLLMGLARVVA

AQP11

21

Q8NBQ7
RALMVVSLVLGFLAM

CLDN7

81

O95471
RVLLMLRKMGSNLTA

CTNNBIP1

21

Q9NSA3
SRDELLQVLRMMVGV

CHP1

131

Q99653
ISRHEMLQVLRLMVG

CHP2

131

O43745
RMMAVAADTLQRLGA

CNDP1

76

Q96KN2
TAAQVARVLGMMART

CNOT1

286

A5YKK6
LLRMTLGREVMSPLQ

NLN

21

Q9BYT8
MVISESMDILFRIRG

UFSP2

1

Q9NUQ7
LVSLRDLIEMMSIGT

SLC7A14

401

Q8TBB6
LIMLAMTALTVRRSE

SLC49A3

391

Q6UXD7
MAASVLNTVLRRLPM

MRPS18B

1

Q9Y676
RTIIGGAQIIDLMML

EEFSEC

101

P57772
LELGLQVMRMTLSTL

ZSWIM5

866

Q9P217
RRMLGILGDVNSIMD

RALGAPA1

1066

Q6GYQ0
TLLLMASQEPQRMSR

VWF

1381

P04275
ILRSMLYRGSEVMRE

MTREX

231

P42285
GAARSLLRQTDPMIM

SMU1

91

Q2TAY7
VNARLEFSRGLMMLV

RINT1

366

Q6NUQ1
AGLSSELRSVLVMML

PKMYT1

326

Q99640
ARLHQREIQVMMGSL

RMND5B

226

Q96G75
REIQVMMGSLVYLRL

RMND5B

231

Q96G75
RGVLMTLLQQSAMTL

SGF29

116

Q96ES7
MLTALDQMRRSIVSE

STAT3

206

P40763
MLEAVVMHLGIRSAR

THEMIS2

131

Q5TEJ8
IREQRVTGLMIFILM

SLC4A10

906

Q6U841
VGEVLMRIVRALGDM

TANGO6

936

Q9C0B7
RLNMDLDRASLDLMI

WAPL

731

Q7Z5K2
PMQRLLTSRGLEQQM

USF3

1626

Q68DE3
ADMMVIRSLSLIRLE

RFPL2

31

O75678
AMRYNRLTVLAGAML

TMEM165

121

Q9HC07
RLGGFVMNILSRLIM

SYMPK

1011

Q92797
RVRISADAMMQALLG

TNNI3

146

P19429
DIMKGLTLERNRMSV

ZNF844

436

Q08AG5
MRDSNGARMLTLITE

ZSWIM6

401

Q9HCJ5
LELGLQVMRMTLSTL

ZSWIM6

896

Q9HCJ5
MGSILGVRREEMEQL

TRIP11

1806

Q15643
LANVAGMALLRLFRM

SCN7A

586

Q01118
TQPGQARMSIMDRIL

TBCD

176

Q9BTW9
ARMSIMDRILQIAES

TBCD

181

Q9BTW9
RMGMLGTRVLSLVLF

XKR5

186

Q6UX68
MNRGMTEGVTLLILA

RNF145

311

Q96MT1
MNLGVSMLRILFLLD

TMEM273

1

Q5T292
MAIRLRGMDLEETSV

TYMP

76

P19971
MDVLPRALLTRMTVL

HIVEP1

2246

P15822
MGETDLMLAALRTLV

UNC45A

206

Q9H3U1
RNLGMSMRVERSTLD

ZMAT2

106

Q96NC0
LMMEELSLRNNRGSL

MYOZ3

36

Q8TDC0
LDRVALSNRMPMTGL

NDN

176

Q99608