Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainConA-like_dom

CNTNAP3 CNTNAP3B ADGRG4 MEFV FAT3

3.85e-05219335IPR013320
DomainLAM_G_DOMAIN

CNTNAP3 CNTNAP3B FAT3

4.06e-0538333PS50025
DomainLaminin_G_2

CNTNAP3 CNTNAP3B FAT3

4.75e-0540333PF02210
DomainEGF

CNTNAP3 PCSK5 CNTNAP3B HEG1 FAT3

5.38e-05235335SM00181
DomainLamG

CNTNAP3 CNTNAP3B FAT3

6.33e-0544333SM00282
DomainEGF-like_dom

CNTNAP3 PCSK5 CNTNAP3B HEG1 FAT3

7.08e-05249335IPR000742
DomainLaminin_G

CNTNAP3 CNTNAP3B FAT3

1.45e-0458333IPR001791
DomainGalactose-bd-like

CNTNAP3 PCSK5 CNTNAP3B

6.04e-0494333IPR008979
DomainFA58C

CNTNAP3 CNTNAP3B

6.23e-0421332SM00231
DomainFA58C_3

CNTNAP3 CNTNAP3B

6.23e-0421332PS50022
DomainFA58C_1

CNTNAP3 CNTNAP3B

6.23e-0421332PS01285
DomainFA58C_2

CNTNAP3 CNTNAP3B

6.23e-0421332PS01286
Domain-

CNTNAP3 ADGRG4 FAT3

6.23e-04953332.60.120.200
DomainEGF_3

CNTNAP3 CNTNAP3B HEG1 FAT3

7.51e-04235334PS50026
DomainF5_F8_type_C

CNTNAP3 CNTNAP3B

8.15e-0424332PF00754
DomainFA58C

CNTNAP3 CNTNAP3B

8.15e-0424332IPR000421
DomainEGF_1

CNTNAP3 CNTNAP3B HEG1 FAT3

1.02e-03255334PS00022
DomainEGF_2

CNTNAP3 CNTNAP3B HEG1 FAT3

1.17e-03265334PS01186
DomainFibrinogen_a/b/g_C_dom

CNTNAP3 CNTNAP3B

1.45e-0332332IPR002181
DomainFIBRINOGEN_C_2

CNTNAP3 CNTNAP3B

1.45e-0332332PS51406
DomainFIBRINOGEN_C_1

CNTNAP3 CNTNAP3B

1.45e-0332332PS00514
Domain-

CNTNAP3 PCSK5

7.36e-03733322.60.120.260
DomainSH3_2

DOCK2 TJP1

1.01e-0286332IPR011511
DomainEGF_CA

HEG1 FAT3

1.01e-0286332PF07645
DomainSH3_2

DOCK2 TJP1

1.01e-0286332PF07653
DomainEGF-like_CS

CNTNAP3 HEG1 FAT3

1.08e-02261333IPR013032
DomainEGF_Ca-bd_CS

HEG1 FAT3

1.27e-0297332IPR018097
DomainEGF_CA

HEG1 FAT3

1.32e-0299332PS01187
DomainASX_HYDROXYL

HEG1 FAT3

1.35e-02100332PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

HEG1 FAT3

1.50e-02106332IPR000152
PathwayWP_1Q211_COPY_NUMBER_VARIATION_SYNDROME

KIRREL1 NBPF12 TJP1

1.75e-0529253M39890
Pubmed

A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.

NBPF19 NBPF15 NBPF12 NBPF20

5.71e-092136416079250
Pubmed

The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice.

CNTNAP3 CNTNAP3B

1.04e-06236231150793
Pubmed

The carboxyl terminus of Neph family members binds to the PDZ domain protein zonula occludens-1.

KIRREL1 TJP1

1.04e-06236212578837
Pubmed

Solution structure analysis of cytoplasmic domain of podocyte protein Neph1 using small/wide angle x-ray scattering (SWAXS).

KIRREL1 TJP1

1.04e-06236222262837
Pubmed

Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.

CNTNAP3 CNTNAP3B

1.04e-06236226807827
Pubmed

Ischemic injury to kidney induces glomerular podocyte effacement and dissociation of slit diaphragm proteins Neph1 and ZO-1.

KIRREL1 TJP1

3.12e-06336218922801
Pubmed

Neph1 and nephrin interaction in the slit diaphragm is an important determinant of glomerular permeability.

KIRREL1 TJP1

3.12e-06336212865409
Pubmed

Motor protein Myo1c is a podocyte protein that facilitates the transport of slit diaphragm protein Neph1 to the podocyte membrane.

KIRREL1 TJP1

6.24e-06436221402783
Pubmed

Variant mapping and mutation discovery in inbred mice using next-generation sequencing.

PCSK5 ABCA12

6.24e-06436226552429
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

SLC38A2 NBAS KIRREL1 ESPL1 TASOR TJP1 SLC26A6

8.80e-0673336734672954
Pubmed

In trans neuregulin3-Caspr3 interaction controls DA axonal bassoon cluster development.

CNTNAP3 CNTNAP3B

1.56e-05636234143959
Pubmed

NEPH1 defines a novel family of podocin interacting proteins.

KIRREL1 TJP1

2.91e-05836212424224
Pubmed

Evolutionary history and genome organization of DUF1220 protein domains.

NBPF15 NBPF12

4.66e-051036222973535
Pubmed

Cell adhesion molecule contactin-associated protein 3 is expressed in the mouse basal ganglia during early postnatal stages.

CNTNAP3 CNTNAP3B

1.40e-041736226389685
Pubmed

FoxP1 orchestration of ASD-relevant signaling pathways in the striatum.

CNTNAP3 CNTNAP3B

2.38e-042236226494785
Pubmed

Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.

DOCK2 KIRREL1 SRPK2

3.56e-0413336315144186
Pubmed

Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons.

CNTNAP3 CNTNAP3B

4.16e-042936231491374
Pubmed

FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration.

BRCA2 SACS

8.74e-044236229348145
Pubmed

Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease.

PCSK5 CLVS1

9.16e-044336221116278
InteractionCST9L interactions

CNTNAP3 NBPF19 PCSK5 CNTNAP3B

1.11e-0578364int:CST9L
CytobandEnsembl 112 genes in cytogenetic band chr1q21

NBPF19 NBPF15 NBPF12 NBPF20

2.79e-04404364chr1q21
Cytoband1q21.2

NBPF15 NBPF20

1.44e-03713621q21.2
GeneFamilyNeuroblastoma breakpoint family

NBPF19 NBPF15 NBPF12 NBPF20

9.51e-0923204662
CoexpressionDESCARTES_ORGANOGENESIS_INHIBITORY_INTERNEURONS

CNTNAP3 CNTNAP3B SLC18A2

8.64e-0630353MM3663
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLEC1A SRPK2 HEG1 KIAA0825 TJP1

4.67e-071933656e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLEC1A SRPK2 HEG1 KIAA0825 TJP1

4.79e-071943650b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLEC1A CNTNAP3B HEG1 TJP1 DISP1

5.29e-07198365d5990cab01de6e6f3757f5a50ef70ced711bb1fa
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CLEC1A HEG1 SLC18A2 DISP1

1.03e-051693647c994653b0d629dfb046755d6b678452de0a15d2
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 ABCA12 SLC18A2 MEFV

1.08e-05171364b6502a81df4f25660f3ae4b7443a1d999df2d32b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic-Mast_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 ABCA12 SLC18A2 MEFV

1.08e-05171364ac37c80c832504986c7a201d84f4b6aff5e5f323
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ZNF8 NBPF12 KIAA0825 SLC26A6

1.24e-0517736436b5d29caa9cffbc0284f771a4db71aa72171a89
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

DOCK2 CLEC1A HEG1 MEFV

1.29e-05179364cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CNTNAP3 CLEC1A CNTNAP3B HEG1

1.32e-0518036427e8bbee388e64dd79d70b160b76d45b1f398006
ToppCelldroplet-Heart-nan-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEG1 SACS TJP1 SLC18A2

1.50e-051863640ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein|Children_(3_yrs) / Lineage, Cell type, age group and donor

CNTNAP3 CLEC1A CNTNAP3B HEG1

1.53e-05187364e35716f8b482be3bf5ab79f087a9caf67a9d197a
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLEC1A HEG1 TJP1 DISP1

1.57e-0518836473f6ec915934154f435a376cb274b058ff7c5f35
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CNTNAP3 PCSK5 CNTNAP3B HEG1

1.60e-051893646463890d8dbee4bc198f91628a5f784970de786a
ToppCellEndothelial-endothelial_cell_of_artery|World / Lineage, Cell type, age group and donor

CNTNAP3 CLEC1A CNTNAP3B HEG1

1.60e-05189364fdd89c71113ac99b7c800c6def8888e512ff1128
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLEC1A HEG1 TJP1 DISP1

1.63e-05190364474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCellEndothelial-C|World / shred on cell class and cell subclass (v4)

CLEC1A PCSK5 HEG1 TJP1

1.67e-05191364bf203931f973098b79ec681d1dd0854419819e98
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLEC1A HEG1 TJP1 DISP1

1.70e-05192364c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLEC1A SRPK2 HEG1 TJP1

1.74e-05193364e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCellLPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLEC1A HEG1 TJP1 DISP1

1.74e-05193364a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCelltumor_Lung-Endothelial_cells-Stalk-like_ECs|tumor_Lung / Location, Cell class and cell subclass

CNTNAP3 CLEC1A CNTNAP3B HEG1

1.74e-0519336421fec35587ffb5c0157e54a821ce3ffd3e24e536
ToppCellLPS-IL1RA-Endothelial-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLEC1A HEG1 TJP1 DISP1

1.77e-051943641d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCellLPS-IL1RA-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLEC1A HEG1 TJP1 DISP1

1.77e-0519436443f92b0533e26633dc94cce554045d641ef8fd76
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLEC1A PCSK5 HEG1 TJP1

1.77e-0519436444c7d4b75f3b7c9301eba20610e548a01a84ae40
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLEC1A PCSK5 HEG1 TJP1

1.77e-051943647f24023df47935286f185dd428d48797daf26f49
ToppCell3'-Child04-06-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CNTNAP3 CLEC1A HEG1 TJP1

1.81e-05195364527a5a50d6e2cbbbd64d11609e5cde2e33f14797
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLEC1A PCSK5 HEG1 TJP1

1.84e-05196364cf7f384c1771274e766bab03ecc3dfbd13f2df60
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CNTNAP3 CLEC1A HEG1 TJP1

1.88e-051973647a1a3839b2c965136663241b0d4e96c64cfb656a
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CNTNAP3 CLEC1A HEG1 TJP1

1.92e-0519836413203249e5743ba2699871c184d141207e550a86
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

BRCA2 SACS CLVS1 FAT3

1.92e-051983647225a6194c52b01c581e58d3cda107c4af96dc4f
ToppCellILEUM-inflamed-(7)_Endothelial_cell|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CLEC1A CNTNAP3B HEG1 TJP1

1.96e-0519936497052c28e354833901f28d339b09f97f50a5b752
ToppCellILEUM-inflamed-(7)_ACKR1+_endothelial_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CLEC1A CNTNAP3B HEG1 TJP1

1.96e-051993645c799115a6e95bcd896e4ad10bd272705c9a4e2c
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_capillary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CLEC1A HEG1 TJP1 DISP1

2.00e-052003645ab588808c1fc384019413401ab4bf9bc06bf529
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_low-phase|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA2 ABCA12 SLC18A2

2.12e-04144363f6061dd965a2b2fe6ad864f8aecc06d2e74881ce
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-NP-L5_NP_VISp_Trhr_Cpne7|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PCSK5 ABCA12 SCAI

2.35e-041493638638b3819193d11411df58964069fec583f617f4
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-NP|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PCSK5 ABCA12 SCAI

2.49e-04152363b6a7453fbf9f898e4f222b215907c9a110baa2f6
ToppCellfacs-Trachea-24m-Hematologic-myeloid-granulocyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC18A2 MEFV FAT3

2.73e-04157363188d2f85babcd4eefe20e7a392d851b2e1185bab
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CNTNAP3 BRCA2 KIAA0825

2.73e-04157363410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLEC1A HEG1 MEFV

3.00e-04162363c399b9e4854916a59f5cae2d8dbf19660f8759be
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLEC1A HEG1 MEFV

3.00e-04162363a291248b693c771845174393934a782f1d8bd7ce
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CNTNAP3 PCSK5 HEG1

3.00e-0416236325bb1b9709f960fdf90faff56e874f52a8f5d17e
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MEFV TAF1B SCAI

3.28e-04167363a54b8e03987a7b067173121902e1811a3d003692
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 BRCA2 ESPL1

3.39e-0416936354b13ab02b4c187f4754045ecfcf409749e7ccc0
ToppCellfacs-Trachea-18m-Hematologic-myeloid-granulocyte-granulocyte_l26|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DOCK2 SLC18A2 FAT3

3.45e-041703634b1c84b35b7242a297ffdb9c23a6d982acf1bed5
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CLEC1A CNTNAP3B HEG1

3.57e-04172363de9b11ab109d04937186c09772cec9105a935f95
ToppCellEndothelial-A-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

CLEC1A CNTNAP3B HEG1

3.57e-04172363a3201773a25832e92dd113fad165f1ecd37f5e91
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A2 TASOR FAT3

3.63e-04173363869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A2 TASOR FAT3

3.63e-041733630672bd8a4a9d18af343d01f09253fb3388896c10
ToppCell3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CNTNAP3 CLEC1A HEG1

3.63e-04173363b57d14e2c2368304cb903562d06ce8228f53857c
ToppCellfacs-Brain_Myeloid-Cerebellum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A2 TASOR FAT3

3.63e-04173363870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCellE16.5-Immune-Immune_Myeloid-Granulocytic-Basophil|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DOCK2 SLC18A2 FAT3

3.63e-041733632cba41c3d9d3076f703115d19729073a3ac3feb6
ToppCellE16.5-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DOCK2 SLC18A2 FAT3

3.63e-0417336311d69a4ab4a87b8820cd3bd204de8c4124450a90
ToppCellNS-control-d_0-4-Myeloid-Monocyte-derived_Macrophage|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DOCK2 CLEC1A MEFV

3.70e-04174363758984730cd1c3ccf6866a3a8f03d6e002f3edb6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 BRCA2 ESPL1

3.70e-041743637b318796728001c17b4043d2b033330c7be40c78
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A2 TASOR FAT3

3.76e-041753631ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 CNTNAP3B KIRREL1

3.76e-041753639d797888edb39fd12fd9cfc698a42b7bed19a5b5
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L2-4_SST_AHR|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 PCSK5 CNTNAP3B

3.82e-04176363322259a35f5c97d73ce7f75835dcdb5c954c91f8
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 CNTNAP3B KIRREL1

3.82e-04176363682a1dfcc507ec540f5fadf08e872533ea9f0291
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 CNTNAP3B HEG1

3.82e-041763634843af68f013732c28a8b8edad30d5fa0f2b084b
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PCSK5 HEG1 SLC18A2

3.82e-0417636396779273b94345250cf53ba671203345b43d9e00
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L1-6_PVALB_SCUBE3_(Chandelier_1)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 CNTNAP3B HEG1

3.82e-0417636395d5a4fdff1b9c715636684d22e06f8727ac0e7a
ToppCellAdult-Endothelial-endothelial_cell_of_vein|Adult / Lineage, Cell type, age group and donor

CLEC1A CNTNAP3B HEG1

3.82e-04176363043683c61c5d1a7f8a4666a612310246bd3d83a2
ToppCelldroplet-Limb_Muscle-nan-21m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCD3 KIAA0825 CLVS1

3.88e-04177363291231b1520c135e92739e201495fe1935efa927
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_artery|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CLEC1A PCSK5 HEG1

3.88e-041773635ff8dcfb030312126695d53a026d2e104a401b83
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLEC1A CNTNAP3B HEG1

3.88e-041773631921226196b2ab7919d9f843e60d9f4bd9ec9c57
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 PCSK5 CNTNAP3B

3.88e-04177363bde307e67ad8e48a5ff4c0827015f4688f6b3e46
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 PCSK5 CNTNAP3B

3.88e-041773634c069f0d044a96118090b85ca592a21d6b5d9399
ToppCellPCW_13-14-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CNTNAP3 CLEC1A CNTNAP3B

3.95e-04178363c227da59dc7beb73f84405bf13356bdeb59d9338
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 PCSK5 CNTNAP3B

4.01e-041793637954c0026754ab869b88ab7feb13c2f27d6e272d
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CNTNAP3 DOCK2 CNTNAP3B

4.01e-0417936314fc8ccb6b215063d747643f47d780d2b237eb67
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 CNTNAP3B HEG1

4.01e-041793633b0f8781232e1d42b6f8913bc989a14b3f978e79
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 CNTNAP3B KIRREL1

4.01e-04179363d1365d48d1b017a7917f4f63a82ac4720c3d87df
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 PCSK5 CNTNAP3B

4.08e-04180363b514c55e52b46e8a1a2f09ed2c59a7683367a505
ToppCellLPS-IL1RA-Endothelial-Endothelial-Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLEC1A TJP1 DISP1

4.08e-04180363544fb373a3346186ec60afe2cfcf141bb04a1eed
ToppCell3'-Child09-12-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NBPF19 CLVS1 ADGRG4

4.08e-04180363b234668bf181522807470e396792e1b54890b719
ToppCellLPS-antiTNF-Endothelial-Endothelial-Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLEC1A TJP1 DISP1

4.08e-0418036330cf3c7ee29694eaccb89bf8053a82037d5c9f1d
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PCSK5 HEG1 TJP1

4.15e-041813634d7793026373cbcf04b15c77f95f1025d07d4c00
ToppCellCOVID-19_Convalescent|World / Disease condition and Cell class

NBPF19 NBPF15 NBPF20

4.15e-04181363a62115a8da486fc61225901c72b1ec70bcaf4c36
ToppCellCOPD-Myeloid-Mast|World / Disease state, Lineage and Cell class

NBAS HEG1 SLC18A2

4.21e-0418236368a1e7b804f309bfd6c23d65fad20a9a962712ae
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCSK5 TJP1 SLC18A2

4.21e-04182363c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_A|E18.5-samps / Age Group, Lineage, Cell class and subclass

CLEC1A ESPL1 TJP1

4.21e-04182363ea4f6c8f600ffe9f8e0609637b3371a5ac48ca03
ToppCellpdx-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CNTNAP3 DOCK2 CNTNAP3B

4.21e-041823637b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCSK5 TJP1 SLC18A2

4.21e-04182363d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 CNTNAP3B KIRREL1

4.21e-04182363a3c5c0eff527c8d3848acda14af8f9e99c69b0de
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 CNTNAP3B KIRREL1

4.28e-041833635a541a7f6c3514be8a13e988185dfe388c874f8b
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PCSK5 HEG1 TJP1

4.28e-041833633427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PLCD3 KIRREL1 HEG1

4.35e-04184363ae0a77e3e520a246b17776bb19503519636b02ee
ToppCellPCW_10-12-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CNTNAP3 CLEC1A CNTNAP3B

4.35e-04184363a809b0fa52df8a159f60f87eefcef61220af5e34
ToppCellmetastatic_Brain-Endothelial_cells-Stalk-like_ECs|metastatic_Brain / Location, Cell class and cell subclass

CNTNAP3B NBPF15 HEG1

4.42e-04185363ad52970e88e8947ef256095bd4b40229b912d58a
ToppCellEndothelial-A-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

CNTNAP3 CNTNAP3B HEG1

4.42e-04185363ae49c61f6ecf128fe2a958b8c75c83688da75f59
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CNTNAP3 CNTNAP3B HEG1

4.42e-04185363a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCellCOPD-Myeloid-Mast|COPD / Disease state, Lineage and Cell class

NBAS HEG1 SLC18A2

4.49e-04186363def6f0f284acc2154738574c8c5d3d2a5ef1f208
ToppCellAnterior_Cingulate_gyrus_(CgG)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3 PCSK5 CNTNAP3B

4.49e-0418636332af3f211f9ad5d5c6b86b83325cfbf2f8466b56
ToppCellAdult-Endothelial-endothelial_cell_of_artery|Adult / Lineage, Cell type, age group and donor

CLEC1A CNTNAP3B HEG1

4.49e-041863632d1c4ea2e401db89971582ee54618a8b0c81b8ac
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLCD3 PCSK5 SLC18A2

4.49e-04186363c116cc9f41971622264434ebe29d18e719b0ae19
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Endothelial-endothelial_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC1A PCSK5 TJP1

4.56e-041873633548a9914c2b2f5d805798ce22ab26eab6d03897
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Endothelial-endothelial_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC1A PCSK5 TJP1

4.56e-04187363f4de4b7af1fdfbd628b1f509c060c1079d2e5437
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 BRCA2 ESPL1

4.56e-0418736373931a5ea73799095daff100b5f18853c57c74dc
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Endothelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC1A PCSK5 TJP1

4.56e-0418736381754e965848b718be20ee97ce072ce426938a69
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLEC1A HEG1 DISP1

4.56e-04187363f3397dbc23b6c2f24e2c1ba887d8f9aef3ee01a1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PCSK5 CNTNAP3B HEG1

4.63e-04188363c2c51c6526defe2600302901159b8abbb58d7595
Diseaseautosomal recessive intellectual developmental disorder (implicated_via_orthology)

CNTNAP3 CNTNAP3B

3.18e-058322DOID:0060308 (implicated_via_orthology)
Diseaseage at assessment, pelvic organ prolapse

SACS TJP1

1.00e-0343322EFO_0004710, EFO_0008007
Diseaselung carcinoma, estrogen-receptor negative breast cancer, ovarian endometrioid carcinoma, colorectal cancer, prostate carcinoma, ovarian serous carcinoma, breast carcinoma, ovarian carcinoma, lung adenocarcinoma, squamous cell lung carcinoma

BRCA2 NEK10

1.46e-0352322EFO_0000305, EFO_0000571, EFO_0000708, EFO_0001071, EFO_0001075, EFO_0001663, EFO_1000650, EFO_1001515, EFO_1001516, MONDO_0005575
DiseaseProstate cancer, familial

DOCK2 BRCA2

2.55e-0369322C2931456

Protein segments in the cluster

PeptideGeneStartEntry
TYHFQEHYTLSENSS

CNTNAP3

1011

Q9BZ76
NFTSAFHENTTYTEY

ADGRG4

681

Q8IZF6
FHENTTYTEYLSATT

ADGRG4

686

Q8IZF6
TSEQTAFYANYHPST

ABCA12

1786

Q86UK0
TSFTTAAAFYANYVS

DISP1

611

Q96F81
TNYNYSTSESSFISH

KIAA0825

76

Q8IV33
QSCSISYYFDHSSEN

PCSK5

816

Q92824
EESGYYNFTSNRYHS

NEK10

1146

Q6ZWH5
SSFIETYSVYQHDFC

OR5A2

156

Q8NGI9
FYNVTARSHIYTFAS

MEFV

731

O15553
SEYSSFFHAQTERSN

HEG1

596

Q9ULI3
QSYQESHCFSFSSHY

NBAS

221

A2RRP1
KQNSLYSFSDHYTHF

CCDC82

326

Q8N4S0
TASYTSNLAYSFYSH

ESPL1

456

Q14674
HYSFYIETFQTSSEL

DOCK2

951

Q92608
SNSYSYHSDEVYNDS

BRCA2

1746

P51587
FSSDHYNTCVYENTA

FAT3

3131

Q8TDW7
ATATRFSYTSQHSDY

KIRREL1

731

Q96J84
FSYTSQHSDYGQRFQ

KIRREL1

736

Q96J84
SSKTFSDEDYYQFQH

SACS

1236

Q9NZJ4
FTAFTTAASAYSYYH

CRLS1

276

Q9UJA2
TYHFQEHYTLSENSS

CNTNAP3B

1011

Q96NU0
SFQHYRSVFYSFEEQ

NBPF12

1411

Q5TAG4
SYQSYSSTFHSLEEQ

NBPF15

306

Q8N660
SYQSYSSTFHSLEEQ

NBPF19

306

A0A087WUL8
SFQHYRSVFYSFEEQ

NBPF20

5161

P0DPF2
HVTTYEESNYSLSYQ

TAF1B

526

Q53T94
SATVYFANAEFYSDA

SLC26A6

546

Q9BXS9
STEQDSYSNFQVYHS

TASOR

1586

Q9UK61
LEFAASQSYSEFFYS

CLEC1A

181

Q8NC01
SQFGHYFETTYDTSY

C11orf1

91

Q9H5F2
DYSDENDYTHTSYNA

CLVS1

291

Q8IUQ0
YFISSSHNTYLTDSQ

PLCD3

346

Q8N3E9
DSSSYSSNSDFNYSY

SLC38A2

16

Q96QD8
AESDYTYSSSYEQFN

SRPK2

421

P78362
TSETSYLNEAFSFYS

SCAI

141

Q8N9R8
YESSSYTDQFSRNYE

TJP1

1061

Q07157
YTYDSQITDSEHNSS

ZNF8

201

P17098
ISDSFQSIFSYYDNS

SLC18A2

71

Q05940