Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	eukaryotic translation initiation factor 3 complex, eIF3m	EIF3C EIF3CL	1.62e-04	9	45	2	GO:0071541
GeneOntologyCellularComponent	eukaryotic translation initiation factor 3 complex	EIF3C EIF3CL	5.33e-04	16	45	2	GO:0005852
GeneOntologyCellularComponent	eukaryotic 48S preinitiation complex	EIF3C EIF3CL	6.78e-04	18	45	2	GO:0033290
GeneOntologyCellularComponent	eukaryotic 43S preinitiation complex	EIF3C EIF3CL	7.57e-04	19	45	2	GO:0016282
GeneOntologyCellularComponent	translation preinitiation complex	EIF3C EIF3CL	8.40e-04	20	45	2	GO:0070993
Domain	Sel1	SEL1L EEF2K LRP2BP	6.78e-07	8	44	3	PF08238
Domain	Sel1-like	SEL1L EEF2K LRP2BP	1.01e-06	9	44	3	IPR006597
Domain	EIF3C_N_dom	EIF3C EIF3CL	5.42e-06	2	44	2	IPR008905
Domain	eIF-3c_N	EIF3C EIF3CL	5.42e-06	2	44	2	PF05470
Domain	EIF3C	EIF3C EIF3CL	5.42e-06	2	44	2	IPR027516
Domain	zf-RNPHF	HNRNPH1 HNRNPH2	1.62e-05	3	44	2	PF08080
Domain	Znf_CHHC	HNRNPH1 HNRNPH2	1.62e-05	3	44	2	IPR012996
Domain	SEL1	SEL1L LRP2BP	1.51e-04	8	44	2	SM00671
Domain	Kelch	KLHDC8A KLHL20 KBTBD8	3.44e-04	58	44	3	SM00612
Domain	Gal_Oxase/kelch_b-propeller	KLHDC8A KLHL20 KBTBD8	3.62e-04	59	44	3	IPR011043
Domain	Kelch_1	KLHDC8A KLHL20 KBTBD8	5.98e-04	70	44	3	PF01344
Domain	Kelch_1	KLHDC8A KLHL20 KBTBD8	5.98e-04	70	44	3	IPR006652
Domain	PINT	EIF3C EIF3CL	6.37e-04	16	44	2	SM00088
Domain	PCI_dom	EIF3C EIF3CL	7.21e-04	17	44	2	IPR000717
Domain	PCI	EIF3C EIF3CL	7.21e-04	17	44	2	PF01399
Domain	FGF	FGF16 FGF22	1.22e-03	22	44	2	SM00442
Domain	FGF	FGF16 FGF22	1.22e-03	22	44	2	PF00167
Domain	HBGF_FGF	FGF16 FGF22	1.22e-03	22	44	2	PS00247
Domain	Fibroblast_GF_fam	FGF16 FGF22	1.22e-03	22	44	2	IPR002209
Domain	IL-1_fam/FGF_fam	FGF16 FGF22	1.33e-03	23	44	2	IPR028142
Domain	RRM_1	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	1.43e-03	208	44	4	PF00076
Domain	RRM	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	1.67e-03	217	44	4	SM00360
Domain	ACR	ADAM19 ADAMTS14	1.83e-03	27	44	2	SM00608
Domain	ADAM_Cys-rich	ADAM19 ADAMTS14	1.83e-03	27	44	2	IPR006586
Domain	RRM_dom	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	1.97e-03	227	44	4	IPR000504
Domain	RRM	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	2.07e-03	230	44	4	PS50102
Domain	TPR-like_helical_dom	SEL1L EEF2K CTR9 LRP2BP	2.17e-03	233	44	4	IPR011990
Domain	-	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	2.56e-03	244	44	4	3.30.70.330
Domain	Nucleotide-bd_a/b_plait	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	3.13e-03	258	44	4	IPR012677
Domain	Cytokine_IL1-like	FGF16 FGF22	3.25e-03	36	44	2	IPR008996
Domain	Peptidase_M12B_N	ADAM19 ADAMTS14	3.80e-03	39	44	2	IPR002870
Domain	Pep_M12B_propep	ADAM19 ADAMTS14	3.80e-03	39	44	2	PF01562
Domain	DISINTEGRIN_1	ADAM19 ADAMTS14	4.00e-03	40	44	2	PS00427
Domain	Reprolysin	ADAM19 ADAMTS14	4.00e-03	40	44	2	PF01421
Domain	ADAM_MEPRO	ADAM19 ADAMTS14	4.00e-03	40	44	2	PS50215
Domain	DISINTEGRIN_2	ADAM19 ADAMTS14	4.00e-03	40	44	2	PS50214
Domain	Peptidase_M12B	ADAM19 ADAMTS14	4.00e-03	40	44	2	IPR001590
Domain	CYSTEINE_SWITCH	ADAM19 ADAMTS14	4.20e-03	41	44	2	PS00546
Domain	Disintegrin_dom	ADAM19 ADAMTS14	4.20e-03	41	44	2	IPR001762
Domain	BTB-kelch_protein	KLHL20 KBTBD8	4.61e-03	43	44	2	IPR017096
Domain	Pept_M10_metallopeptidase	ADAM19 ADAMTS14	4.61e-03	43	44	2	IPR001818
Domain	-	KLHDC8A KBTBD8	5.71e-03	48	44	2	2.120.10.80
Domain	TPR_2	CTR9 LRP2BP	6.18e-03	50	44	2	PF07719
Domain	TPR_2	CTR9 LRP2BP	6.18e-03	50	44	2	IPR013105
Domain	SOLCAR	SLC25A22 SLC25A35	6.93e-03	53	44	2	PS50920
Domain	-	SLC25A22 SLC25A35	6.93e-03	53	44	2	1.50.40.10
Domain	Mitochondrial_sb/sol_carrier	SLC25A22 SLC25A35	6.93e-03	53	44	2	IPR018108
Domain	Mito_carr	SLC25A22 SLC25A35	6.93e-03	53	44	2	PF00153
Domain	Mt_carrier_dom	SLC25A22 SLC25A35	6.93e-03	53	44	2	IPR023395
Pubmed	Expanded CUG repeats Dysregulate RNA splicing by altering the stoichiometry of the muscleblind 1 complex.	HNRNPH1 HNRNPH2 HNRNPH3	3.32e-07	11	45	3	21900255
Pubmed	A murine model of hnRNPH2-related neurodevelopmental disorder reveals a mechanism for genetic compensation by Hnrnph1.	HNRNPH1 HNRNPH2 HNRNPH3	4.42e-07	12	45	3	37463454
Pubmed	Tandem immunoprecipitation approach to identify HIV-1 Gag associated host factors.	HNRNPH1 HNRNPH2 HNRNPH3	1.12e-06	16	45	3	24690621
Pubmed	EIF3C Promotes Lung Cancer Tumorigenesis by Regulating the APP/HSPA1A/LMNB1 Axis.	EIF3C EIF3CL	1.64e-06	2	45	2	36157221
Pubmed	Interaction of antiproliferative protein Tob with the CCR4-NOT deadenylase complex.	HNRNPH1 HNRNPH2 HNRNPH3	3.06e-06	22	45	3	18377426
Pubmed	hnRNPs H, H' and F behave differently with respect to posttranslational cleavage and subcellular localization.	HNRNPH1 HNRNPH2	4.91e-06	3	45	2	10456323
Pubmed	Heterogeneous nuclear ribonucleoproteins F and H/H' show differential expression in normal and selected cancer tissues.	HNRNPH1 HNRNPH2	4.91e-06	3	45	2	14980514
Pubmed	Heterogeneous nuclear ribonucleoprotein H1/H2-dependent unsplicing of thymidine phosphorylase results in anticancer drug resistance.	HNRNPH1 HNRNPH2	4.91e-06	3	45	2	21068389
Pubmed	Heterogeneous nuclear ribonucleoproteins H, H', and F are members of a ubiquitously expressed subfamily of related but distinct proteins encoded by genes mapping to different chromosomes.	HNRNPH1 HNRNPH2	4.91e-06	3	45	2	7499401
Pubmed	Interaction between the Ret finger protein and the Int-6 gene product and co-localisation into nuclear bodies.	EIF3C EIF3CL	9.81e-06	4	45	2	10504338
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	SLC25A22 EIF3C PAXBP1 PC NSD2 CTR9 HNRNPH1 NDUFV1 HNRNPH3 EIF3CL	1.11e-05	1425	45	10	30948266
Pubmed	Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy.	EIF3C HNRNPH1 HNRNPH2 HNRNPH3	1.23e-05	109	45	4	29511296
Pubmed	Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.	TAF15 PAXBP1 CTR9 HNRNPH1 HNRNPH3	1.59e-05	244	45	5	29884807
Pubmed	A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis.	TAF15 PAXBP1 HNRNPH1 HNRNPH2 HNRNPH3	1.92e-05	254	45	5	28431233
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	EIF3C ANK2 HNRNPH1 HNRNPH2 EIF3CL	2.62e-05	271	45	5	32433965
Pubmed	A Mutation in Hnrnph1 That Decreases Methamphetamine-Induced Reinforcement, Reward, and Dopamine Release and Increases Synaptosomal hnRNP H and Mitochondrial Proteins.	HNRNPH1 HNRNPH2	3.42e-05	7	45	2	31704785
Pubmed	Age-related expression analysis of mouse liver nuclear protein binding to 3'-untranslated region of Period2 gene.	HNRNPH1 HNRNPH2	3.42e-05	7	45	2	25846207
Pubmed	The PRMT5/WDR77 complex regulates alternative splicing through ZNF326 in breast cancer.	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	3.99e-05	147	45	4	28977470
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	BICD2 NAV2 EEF2K EIF3C CTR9 EIF3CL	4.49e-05	503	45	6	16964243
Pubmed	The m subunit of murine translation initiation factor eIF3 maintains the integrity of the eIF3 complex and is required for embryonic development, homeostasis, and organ size control.	EIF3C EIF3CL	5.86e-05	9	45	2	24003236
Pubmed	The pleiotropic mouse phenotype extra-toes spotting is caused by translation initiation factor Eif3c mutations and is associated with disrupted sonic hedgehog signaling.	EIF3C EIF3CL	5.86e-05	9	45	2	21292980
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	TAF15 EIF3C PAXBP1 NSD2 HNRNPH1 NDUFV1 HNRNPH2 HNRNPH3	6.63e-05	1082	45	8	38697112
Pubmed	mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events.	EIF3C EIF3CL	7.32e-05	10	45	2	16286006
Pubmed	A long pentraxin-3-derived pentapeptide for the therapy of FGF8b-driven steroid hormone-regulated cancers.	FGF16 FGF22	7.32e-05	10	45	2	25912421
Pubmed	Conservation and diversity of eukaryotic translation initiation factor eIF3.	EIF3C EIF3CL	7.32e-05	10	45	2	8995409
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	TAF15 EIF3C PAXBP1 HNRNPH1 HNRNPH2 HNRNPH3	7.42e-05	551	45	6	34728620
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SLC25A22 TAF15 EIF3C ANK2 PC AJM1 HNRNPH1 NDUFV1 EIF3CL	7.65e-05	1431	45	9	37142655
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	BICD2 EIF3C ANK2 PC AJM1 NDUFV1 HNRNPH2 EIF3CL	9.48e-05	1139	45	8	36417873
Pubmed	Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3.	EIF3C EIF3CL	1.07e-04	12	45	2	14519125
Pubmed	Reconstitution reveals the functional core of mammalian eIF3.	EIF3C EIF3CL	1.07e-04	12	45	2	17581632
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	TAF15 EIF3C PAXBP1 CTR9 HNRNPH1 HNRNPH3	1.24e-04	605	45	6	28977666
Pubmed	Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production.	PAXBP1 HNRNPH1 HNRNPH2 HNRNPH3	1.47e-04	206	45	4	22174317
Pubmed	Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.	EIF3C EIF3CL	1.47e-04	14	45	2	18599441
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	BICD2 TAF15 HNRNPH1 HNRNPH2 HNRNPH3	1.62e-04	399	45	5	35987950
Pubmed	Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry.	EIF3C EIF3CL	1.70e-04	15	45	2	17322308
Pubmed	Comparative mapping of two adjacent regions of MMU19 with their human counterpart on HSA11q13.	PC NDUFV1	1.70e-04	15	45	2	9730611
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	SLC25A22 TAF15 EIF3C CTR9 HNRNPH1 HNRNPH2 HNRNPH3 EIF3CL	1.87e-04	1257	45	8	37317656
Pubmed	BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates.	EEF2K HNRNPH1 HNRNPH2 HNRNPH3	2.10e-04	226	45	4	25900982
Pubmed	DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation.	HNRNPH1 HNRNPH2 HNRNPH3	2.13e-04	89	45	3	22446626
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	BICD2 EIF3C ADAM19 TNKS2 ANK2 PC CTR9 RYR3	2.17e-04	1285	45	8	35914814
Pubmed	Blocking PPARγ interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression.	TAF15 HNRNPH1 HNRNPH2	2.20e-04	90	45	3	33087562
Pubmed	Controlling tissue patterning by translational regulation of signaling transcripts through the core translation factor eIF3c.	EIF3C EIF3CL	2.20e-04	17	45	2	34752747
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	TAF15 PAXBP1 PC NSD2 CTR9 HNRNPH1 HNRNPH2 HNRNPH3	2.27e-04	1294	45	8	30804502
Pubmed	Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q.	EIF3C ACSM3 EIF3CL	2.35e-04	92	45	3	10493829
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	TAF15 PAXBP1 PC CTR9 HNRNPH1 HNRNPH2 HNRNPH3 EIF3CL	2.57e-04	1318	45	8	30463901
Pubmed	Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.	TAF15 EIF3C NSD2 HNRNPH1 HNRNPH3	2.58e-04	441	45	5	31239290
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	TAF15 EIF3C PC CTR9 HNRNPH1 HNRNPH2 HNRNPH3	2.60e-04	989	45	7	36424410
Pubmed	Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.	RHBDL2 MCM8	2.76e-04	19	45	2	22267201
Pubmed	Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants.	ANK2 NOS2	2.76e-04	19	45	2	24315451
Pubmed	Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family.	FGF16 FGF22	2.76e-04	19	45	2	16597617
Pubmed	Genomewide association study for determinants of HIV-1 acquisition and viral set point in HIV-1 serodiscordant couples with quantified virus exposure.	NAV2 PC	3.06e-04	20	45	2	22174851
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	BICD2 TAF15 EIF3C HNRNPH1 HNRNPH2 EIF3CL	3.23e-04	723	45	6	34133714
Pubmed	PRDM16 determines specification of ventricular cardiomyocytes by suppressing alternative cell fates.	ANK2 RYR3	3.38e-04	21	45	2	39304345
Pubmed	SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.	EIF3C HNRNPH1 HNRNPH2 HNRNPH3	3.47e-04	258	45	4	37794589
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	BICD2 EEF2K EIF3C MCM8 CTR9 KLHL20 HNRNPH3	3.48e-04	1038	45	7	26673895
Pubmed	Expression of FGFs during early mouse tongue development.	FGF16 FGF22	3.72e-04	22	45	2	26748348
Pubmed	Expression of mouse fibroblast growth factor and fibroblast growth factor receptor genes during early inner ear development.	FGF16 FGF22	4.07e-04	23	45	2	14517998
Pubmed	Identification of proteins interacting with protein arginine methyltransferase 8: the Ewing sarcoma (EWS) protein binds independent of its methylation state.	TAF15 HNRNPH3	4.07e-04	23	45	2	18320585
Pubmed	FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration.	FGF16 FGF22	4.07e-04	23	45	2	23322300
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	SLC25A22 EIF3C PAXBP1 PC CTR9 HNRNPH1 HNRNPH2 HNRNPH3	4.14e-04	1415	45	8	28515276
Pubmed	Dimerization quality control ensures neuronal development and survival.	KLHL20 KBTBD8	4.44e-04	24	45	2	30190310
Pubmed	Oncogenic functions of protein kinase D2 and D3 in regulating multiple cancer-related pathways in breast cancer.	TAF15 HNRNPH1 HNRNPH2	4.63e-04	116	45	3	30652415
Pubmed	Viral immune modulators perturb the human molecular network by common and unique strategies.	HNRNPH1 HNRNPH2 HNRNPH3	4.63e-04	116	45	3	22810585
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	BICD2 EIF3C PAXBP1 CTR9 HNRNPH1 EIF3CL	4.63e-04	774	45	6	15302935
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	NAV2 SLC25A22 ANTXR1 TAF15 ACSM3 ANK2 NSD2 CTR9	4.70e-04	1442	45	8	35575683
Pubmed	FGF signaling directs a center-to-pole expansion of tubulogenesis in mouse testis differentiation.	FGF16 FGF22	4.82e-04	25	45	2	20040496
Pubmed	Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse.	FGF16 FGF22	5.22e-04	26	45	2	20348033
Pubmed	Genetic loci influencing natural variations in femoral bone morphometry in mice.	EIF3C EIF3CL	5.63e-04	27	45	2	11518254
Pubmed	Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development.	FGF16 FGF22	5.63e-04	27	45	2	19544582
Pubmed	FGF-2 deficiency does not influence FGF ligand and receptor expression during development of the nigrostriatal system.	FGF16 FGF22	6.50e-04	29	45	2	21876757
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	BICD2 ANTXR1 TAF15 EIF3C PAXBP1 HNRNPH1 EIF3CL	6.59e-04	1155	45	7	20360068
Pubmed	Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.	BICD2 EEF2K HNRNPH1	6.90e-04	133	45	3	15144186
Pubmed	Inherited genetic variant predisposes to aggressive but not indolent prostate cancer.	RHBDL2 ANK2	6.96e-04	30	45	2	20080650
Pubmed	Comprehensive expression atlas of fibroblast growth factors and their receptors generated by a novel robotic in situ hybridization platform.	FGF16 FGF22	7.43e-04	31	45	2	16123981
Pubmed	NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.	EIF3C PC HNRNPH1 LRP2BP	9.02e-04	333	45	4	32665550
Pubmed	Identification of proteins interacting with the mitochondrial small heat shock protein Hsp22 of Drosophila melanogaster: Implication in mitochondrial homeostasis.	SLC25A22 PC NDUFV1	9.04e-04	146	45	3	29509794
Pubmed	Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC.	EIF3C EIF3CL	1.00e-03	36	45	2	16097034
Pubmed	RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.	SLC25A22 PC HNRNPH1 HNRNPH2	1.02e-03	344	45	4	36282215
Pubmed	hnRNPA1 couples nuclear export and translation of specific mRNAs downstream of FGF-2/S6K2 signalling.	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	1.04e-03	346	45	4	25324306
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	EIF3C ANK2 AJM1 EIF3CL	1.05e-03	347	45	4	17114649
Pubmed	Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia.	TAF15 EIF3C CTR9	1.05e-03	154	45	3	36490346
Pubmed	A targeted proteomic analysis of the ubiquitin-like modifier nedd8 and associated proteins.	HNRNPH1 HNRNPH2	1.12e-03	38	45	2	18247557
Pubmed	Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.	SEL1L SLC25A22 C1RL HNRNPH1 HNRNPH2	1.14e-03	613	45	5	22268729
Pubmed	Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability.	PC HNRNPH1 NDUFV1	1.18e-03	160	45	3	23798571
Interaction	MIRLET7I interactions	TAF15 PAXBP1 HNRNPH1 HNRNPH2 HNRNPH3	4.83e-06	114	44	5	int:MIRLET7I
Interaction	MIRLET7G interactions	TAF15 PAXBP1 HNRNPH1 HNRNPH2 HNRNPH3	5.48e-06	117	44	5	int:MIRLET7G
Interaction	MIR138-1 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	1.45e-05	68	44	4	int:MIR138-1
Interaction	MIR9-3 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	1.63e-05	70	44	4	int:MIR9-3
Interaction	MIR140 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	1.73e-05	71	44	4	int:MIR140
Interaction	MIR122 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	1.73e-05	71	44	4	int:MIR122
Interaction	MIR29B2 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	1.73e-05	71	44	4	int:MIR29B2
Interaction	MIR29B1 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	1.93e-05	73	44	4	int:MIR29B1
Interaction	MIR20A interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	2.03e-05	74	44	4	int:MIR20A
Interaction	MIR15A interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	2.15e-05	75	44	4	int:MIR15A
Interaction	MIR7-3 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	2.26e-05	76	44	4	int:MIR7-3
Interaction	MIR16-1 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	2.26e-05	76	44	4	int:MIR16-1
Interaction	MIR199A2 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	2.26e-05	76	44	4	int:MIR199A2
Interaction	MIR429 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	2.26e-05	76	44	4	int:MIR429
Interaction	MIR9-2 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	2.38e-05	77	44	4	int:MIR9-2
Interaction	MIR200A interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	2.38e-05	77	44	4	int:MIR200A
Interaction	MIR92A1 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	2.51e-05	78	44	4	int:MIR92A1
Interaction	MIR98 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	2.51e-05	78	44	4	int:MIR98
Interaction	MIR451A interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	2.51e-05	78	44	4	int:MIR451A
Interaction	MIR222 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	2.64e-05	79	44	4	int:MIR222
Interaction	MIR206 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	2.64e-05	79	44	4	int:MIR206
Interaction	MIR1-2 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	2.64e-05	79	44	4	int:MIR1-2
Interaction	MIR34C interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	2.64e-05	79	44	4	int:MIR34C
Interaction	MIR143 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	2.77e-05	80	44	4	int:MIR143
Interaction	MIR145 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	2.91e-05	81	44	4	int:MIR145
Interaction	MIR106A interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	3.20e-05	83	44	4	int:MIR106A
Interaction	MIR31 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	3.36e-05	84	44	4	int:MIR31
Interaction	MIR7-2 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	3.36e-05	84	44	4	int:MIR7-2
Interaction	MIR199A1 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	3.36e-05	84	44	4	int:MIR199A1
Interaction	MIR200B interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	3.36e-05	84	44	4	int:MIR200B
Interaction	MIR107 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	3.52e-05	85	44	4	int:MIR107
Interaction	MIR17 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	3.52e-05	85	44	4	int:MIR17
Interaction	MIR18B interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	3.52e-05	85	44	4	int:MIR18B
Interaction	MIR93 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	3.52e-05	85	44	4	int:MIR93
Interaction	MIR9-1 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	3.52e-05	85	44	4	int:MIR9-1
Interaction	MIR16-2 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	3.52e-05	85	44	4	int:MIR16-2
Interaction	MIR20B interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	3.68e-05	86	44	4	int:MIR20B
Interaction	MIR29A interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	3.85e-05	87	44	4	int:MIR29A
Interaction	MIR141 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	4.03e-05	88	44	4	int:MIR141
Interaction	MIR138-2 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	4.03e-05	88	44	4	int:MIR138-2
Interaction	MIR29C interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	4.21e-05	89	44	4	int:MIR29C
Interaction	MIR221 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	4.40e-05	90	44	4	int:MIR221
Interaction	MIR92A2 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	4.40e-05	90	44	4	int:MIR92A2
Interaction	MIR1-1 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	4.40e-05	90	44	4	int:MIR1-1
Interaction	MIR200C interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	4.60e-05	91	44	4	int:MIR200C
Interaction	MIR155 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	4.80e-05	92	44	4	int:MIR155
Interaction	MIR128-1 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	4.80e-05	92	44	4	int:MIR128-1
Interaction	MIR214 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	5.01e-05	93	44	4	int:MIR214
Interaction	MIR205 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	5.01e-05	93	44	4	int:MIR205
Interaction	MIR19B2 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	5.22e-05	94	44	4	int:MIR19B2
Interaction	MIRLET7F1 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	5.22e-05	94	44	4	int:MIRLET7F1
Interaction	MIRLET7A2 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	5.67e-05	96	44	4	int:MIRLET7A2
Interaction	MIRLET7C interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	5.91e-05	97	44	4	int:MIRLET7C
Interaction	MIR21 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	5.91e-05	97	44	4	int:MIR21
Interaction	MIRLET7F2 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	5.91e-05	97	44	4	int:MIRLET7F2
Interaction	MIR363 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	5.91e-05	97	44	4	int:MIR363
Interaction	MIR106B interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	6.15e-05	98	44	4	int:MIR106B
Interaction	MIR128-2 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	6.40e-05	99	44	4	int:MIR128-2
Interaction	MIR19A interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	6.65e-05	100	44	4	int:MIR19A
Interaction	MIRLET7B interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	6.92e-05	101	44	4	int:MIRLET7B
Interaction	MIRLET7D interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	6.92e-05	101	44	4	int:MIRLET7D
Interaction	MIR25 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	6.92e-05	101	44	4	int:MIR25
Interaction	KIRREL3 interactions	KIRREL3 HNRNPH1	6.95e-05	6	44	2	int:KIRREL3
Interaction	MIRLET7A3 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	7.19e-05	102	44	4	int:MIRLET7A3
Interaction	MIR15B interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	7.46e-05	103	44	4	int:MIR15B
Interaction	MIR7-1 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	7.46e-05	103	44	4	int:MIR7-1
Interaction	MIR19B1 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	7.75e-05	104	44	4	int:MIR19B1
Interaction	MIR34A interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	7.75e-05	104	44	4	int:MIR34A
Interaction	MIRLET7E interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	8.35e-05	106	44	4	int:MIRLET7E
Interaction	MIRLET7A1 interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	8.98e-05	108	44	4	int:MIRLET7A1
Interaction	MIR34B interactions	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	9.64e-05	110	44	4	int:MIR34B
Interaction	ZNF692 interactions	NSD2 HNRNPH1 KBTBD8	1.05e-04	42	44	3	int:ZNF692
Interaction	HSD11B2 interactions	HSD11B2 HNRNPH1	1.66e-04	9	44	2	int:HSD11B2
Interaction	SPSB2 interactions	ANTXR1 ACSM3 NOS2	1.88e-04	51	44	3	int:SPSB2
Interaction	ICAM1 interactions	SLC25A22 EIF3C NOS2 HNRNPH1 EIF3CL	2.14e-04	252	44	5	int:ICAM1
Interaction	C1RL interactions	C1RL HNRNPH1	2.53e-04	11	44	2	int:C1RL
Interaction	SMN1 interactions	ACRBP NOS2 NSD2 HNRNPH1 HNRNPH3	4.70e-04	299	44	5	int:SMN1
Interaction	ANO3 interactions	ANO2 CTR9	4.80e-04	15	44	2	int:ANO3
Interaction	COPRS interactions	NOS2 HNRNPH1 HNRNPH2	5.00e-04	71	44	3	int:COPRS
Interaction	ANO7 interactions	ANO2 TAF15 HNRNPH1	5.21e-04	72	44	3	int:ANO7
Interaction	MIR18A interactions	TAF15 HNRNPH1 HNRNPH3	5.43e-04	73	44	3	int:MIR18A
Interaction	PCBP1 interactions	BICD2 TAF15 EIF3C NOS2 NSD2 HNRNPH1 HNRNPH3	5.76e-04	671	44	7	int:PCBP1
Interaction	OCRL interactions	BICD2 TAF15 EIF3C EIF3CL	5.81e-04	176	44	4	int:OCRL
Interaction	HIF1AN interactions	SLC25A22 TNKS2 ANK2 HNRNPH1 KLHL20	6.13e-04	317	44	5	int:HIF1AN
Interaction	ADARB1 interactions	EIF3C ANK2 NSD2 HNRNPH1 HNRNPH2 EIF3CL	6.39e-04	489	44	6	int:ADARB1
Interaction	CDK11B interactions	EIF3C CTR9 HNRNPH1 EIF3CL	6.73e-04	183	44	4	int:CDK11B
Interaction	TPSB2 interactions	SEL1L PC	6.97e-04	18	44	2	int:TPSB2
Interaction	MIR10B interactions	TAF15 HNRNPH1 HNRNPH3	7.62e-04	82	44	3	int:MIR10B
Interaction	DDX43 interactions	HNRNPH1 HNRNPH3	8.63e-04	20	44	2	int:DDX43
Interaction	KLHL9 interactions	BICD2 KLHL20 KBTBD8	9.67e-04	89	44	3	int:KLHL9
Interaction	WDR77 interactions	TAF15 NSD2 HNRNPH1 HNRNPH2 HNRNPH3	1.10e-03	361	44	5	int:WDR77
Cytoband	Ensembl 112 genes in cytogenetic band chr16p12	EEF2K ACSM3 EIF3CL	6.53e-04	172	45	3	chr16p12
Cytoband	12p13.31	C1RL ACRBP	2.83e-03	80	45	2	12p13.31
Cytoband	Ensembl 112 genes in cytogenetic band chr12p13	ANO2 C1RL ACRBP	5.04e-03	353	45	3	chr12p13
Cytoband	11q13	ZFTA NDUFV1	6.03e-03	118	45	2	11q13
GeneFamily	RNA binding motif containing	TAF15 HNRNPH1 HNRNPH2 HNRNPH3	1.95e-04	213	25	4	725
ToppCell	LA\|World / Chamber and Cluster_Paper	NAV2 ANTXR1 KIRREL3 ACSM3 ADAM19	1.47e-06	193	45	5	d4bf89437216baf489ea0239136dcedf3b6714af
ToppCell	mild-Myeloid-Eosinophils\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	EEF2K ACSM3 ADAM19 RYR3	2.20e-05	163	45	4	7c57d541a88e9afa079e95b8a6ecdea60a0c6aaa
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NAV2 KIRREL3 ACSM3 RYR3	3.11e-05	178	45	4	a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NAV2 HSD11B2 ANK2 RYR3	3.61e-05	185	45	4	7dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NAV2 ANTXR1 ADAM19 RYR3	3.61e-05	185	45	4	e58a009aaf342be019a909747b1895d5987d4daf
ToppCell	Mild_COVID-19-Epithelial-AT1/AT2\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	NAV2 RHBDL2 HSD11B2 ANK2	3.61e-05	185	45	4	c55fdba1e3818ec0404d7ab473bf18dd25f2bb0a
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	NAV2 HSD11B2 ANK2 RYR3	3.77e-05	187	45	4	5258674d0346e5c51a4b965efcdc1790c970845d
ToppCell	LA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	NAV2 ANTXR1 KIRREL3 ACSM3	3.77e-05	187	45	4	4ea486991f66c29728d127171a07b81404ec0b78
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NAV2 ANTXR1 ADAM19 RYR3	3.85e-05	188	45	4	4d1e5f85342ae550086609d7680e32730b78b5d2
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	NAV2 ADAM19 ADAMTS14 RYR3	3.93e-05	189	45	4	da9ecc0d7b81c1901f30f97bb44112dc85444a66
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-B_cell-B_cell-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NIPA2 ACSM3 SLC25A35 RYR3	4.35e-05	194	45	4	9a99abc65e7509e7ae8fb392f5ee4b2a83128072
ToppCell	LA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	NAV2 ANTXR1 KIRREL3 ACSM3	4.44e-05	195	45	4	a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCell	5'-Adult-LargeIntestine-Epithelial-Tuft-related-BEST4+_epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EEF2K HSD11B2 ADAMTS14 NSD2	4.71e-05	198	45	4	efdbac7a3a02bff4ca48841772e0c136556c2b9b
ToppCell	LPS_anti-TNF-Hematopoietic_Myeloid-Dendritic_cells-pDC\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	KIRREL3 PAXBP1 ACRBP KBTBD8	4.89e-05	200	45	4	6a34e07e6d77fe3fdd9ff44c4b1e46a023f6d6a2
Disease	–	NOS2 TIRAP	2.23e-04	16	41	2	611162
Disease	Malaria, susceptibility to	NOS2 TIRAP	2.23e-04	16	41	2	cv:C1970028
Disease	Malaria	NOS2 TIRAP	3.52e-04	20	41	2	C0024530
Disease	HIV-1 infection, Susceptibility to viral and mycobacterial infections	NAV2 PC	3.89e-04	21	41	2	EFO_0000180, Orphanet_391311
Disease	malaria (is_implicated_in)	NOS2 TIRAP	5.10e-04	24	41	2	DOID:12365 (is_implicated_in)
Disease	nitric oxide exhalation measurement	ANK2 NOS2	1.28e-03	38	41	2	EFO_0005536
Disease	childhood gender nonconformity	NAV2 PC	1.64e-03	43	41	2	EFO_0020103
Disease	Mitochondrial Diseases	NOS2 NDUFV1	2.13e-03	49	41	2	C0751651
Disease	Acute Cerebrovascular Accidents	ANK2 NOS2	2.58e-03	54	41	2	C0751956
Disease	Alzheimer's disease (implicated_via_orthology)	ANK2 NOS2	2.86e-03	57	41	2	DOID:10652 (implicated_via_orthology)
Disease	Cerebrovascular accident	ANK2 NOS2	3.38e-03	62	41	2	C0038454

Protein segments in the cluster

Peptide	Gene	Start	Entry
SYYGGRGVGGIKRME	ANTXR1	381	Q9H6X2
RVMLDYYREGQGGAG	BICD2	551	Q8TD16
AMFGKSLRYAGYGEG	AIFM3	516	Q96NN9
RMLYGGRRCGNGYLE	ADAM19	411	Q9H013
GRFYGLDLYGGLHMD	ACRBP	426	Q8NEB7
RRMGGYYAGEVRTFP	AJM1	321	C9J069
GRPGSYVYVFDGYRM	ANO2	651	Q9NQ90
RRYYPGQGLGLMYFI	HSD11B2	336	P80365
YGGRLCLGPMFEYQV	ADAMTS14	586	Q8WXS8
GGYGGKMGGRNDYRN	TAF15	571	Q92804
LDGMNYLRYSLEGGR	ANK2	881	Q01484
RYAGYQMPDGSIRGD	NOS2	266	P35228
MNGEYRGRGFGRGRF	MCM8	1	Q9UJA3
AGFERMRRGAYGGGY	HNRNPH2	226	P55795
VFPYMEGDRGSRYQG	NSD2	936	O96028
GYFGMYRGAAVNLTL	SLC25A22	61	Q9H936
MSQGRGKYDFYIGLG	NIPA2	1	Q8N8Q9
RGGYYGAGRGSMYDR	HNRNPH3	121	P31942
GALGLMYLYGQGIRQ	LRP2BP	211	Q9P2M1
SGFYVAMNRRGRLYG	FGF22	91	Q9HCT0
AGFERMRRGAYGGGY	HNRNPH1	226	P31943
GIGERYKFLQEMRGY	PAXBP1	436	Q9Y5B6
KMYAIGGRVYEGDGR	KBTBD8	391	Q8NFY9
MATGELGDLGGYYFR	CFAP300	1	Q9BRQ4
GYRKNEGYMRRGGYR	EIF3C	891	Q99613
DGYRKNEGYMRRGGY	EIF3CL	891	B5ME19
WRLYGGMNYRRLGGG	KLHL20	581	Q9Y2M5
GRFGYLEGQEYRMYN	GBA2	521	Q9HCG7
VLPFFGLGQMYIYRG	CTR9	341	Q6PD62
LYRSGLLGYVSGFGM	C1RL	366	Q9NZP8
DYRVYAAGGMGLDLR	KLHDC8A	126	Q8IYD2
GRLYDYGQRFVLGMG	KIRREL3	686	Q8IZU9
GDGNLGVRGMALFFY	EEF2K	296	O00418
LYQFLMNGIRLGTYG	SLC25A35	71	Q3KQZ1
RYLVGASGGVYALMG	RHBDL2	181	Q9NX52
SGLGMAYLYGRGVQV	SEL1L	451	Q9UBV2
GRAMGARAAYIYIRG	NDUFV1	146	P49821
SGLYLGMNERGELYG	FGF16	111	O43320
YMTDGGLGLYTRRLN	NAV2	906	Q8IVL1
TLRGNFYITGDRGYM	ACSM3	451	Q53FZ2
YLFHMYVGVRAGGGI	RYR3	4716	Q15413
ERHAYIGGMFGAGIY	TNKS2	1046	Q9H2K2
LRFMYYVDGRGPDGG	TIRAP	191	P58753
AYGGGGRGMRVVHSY	PC	196	P11498
RGEYLMDYDGSRRGL	ZFTA	586	C9JLR9