Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncomplement component C3b binding

CFH CFHR1 CFHR2

1.01e-0512733GO:0001851
GeneOntologyMolecularFunctioncalcium ion binding

TPO STAB2 DST MEGF8 CAPN1 FSTL4 PLA2G5 BCAN PLA2G4D ADGRL3 STAB1

8.20e-057497311GO:0005509
GeneOntologyMolecularFunctionopsonin binding

CFH CFHR1 CFHR2

1.02e-0425733GO:0001846
GeneOntologyMolecularFunctionscavenger receptor activity

STAB2 DMBT1 STAB1

1.29e-0427733GO:0005044
GeneOntologyMolecularFunctionhyaluronic acid binding

STAB2 BCAN STAB1

1.60e-0429733GO:0005540
GeneOntologyMolecularFunctioncomplement binding

CFH CFHR1 CFHR2

2.15e-0432733GO:0001848
GeneOntologyMolecularFunctionglycosaminoglycan binding

CFH STAB2 PLA2G5 BCAN DMBT1 STAB1

4.43e-04268736GO:0005539
GeneOntologyMolecularFunctionsemaphorin receptor activity

PLXNA4 PLXNA2

8.50e-0412732GO:0017154
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

STAB2 STAB1

1.53e-0316732GO:0005041
GeneOntologyMolecularFunctioncalcium-dependent phospholipase A2 activity

PLA2G5 PLA2G4D

1.94e-0318732GO:0047498
GeneOntologyMolecularFunctionlow-density lipoprotein particle binding

STAB2 STAB1

1.94e-0318732GO:0030169
GeneOntologyMolecularFunctionintramolecular oxidoreductase activity, transposing C=C bonds

ECI1 DCT

2.17e-0319732GO:0016863
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

STAB2 STAB1

2.65e-0321732GO:0030228
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

KCTD12 BMPR1A TRPA1 GPR61 PIGR P2RY6 PLXNA4 OR56A3 LILRB1 EDA2R PLXNA2 ADGRL3

3.48e-0313537312GO:0004888
GeneOntologyMolecularFunctioncargo receptor activity

STAB2 DMBT1 STAB1

3.74e-0385733GO:0038024
GeneOntologyBiologicalProcessregulation of nervous system development

BMPR1A TENM4 MEGF8 ZPR1 FSTL4 PLXNA4 IST1 BCAN DCT PLXNA2 ADGRL3

1.02e-056257211GO:0051960
DomainSushi

CFH TPO CFHR1 CFHR2 BCAN

1.67e-0652725PF00084
DomainCCP

CFH TPO CFHR1 CFHR2 BCAN

2.02e-0654725SM00032
DomainSUSHI

CFH TPO CFHR1 CFHR2 BCAN

2.42e-0656725PS50923
DomainSushi_SCR_CCP_dom

CFH TPO CFHR1 CFHR2 BCAN

2.65e-0657725IPR000436
DomainEGF

TPO FRAS1 STAB2 TENM4 MEGF8 TENM3 BCAN STAB1

3.34e-06235728SM00181
DomainEGF-like_dom

TPO FRAS1 STAB2 TENM4 MEGF8 TENM3 BCAN STAB1

5.11e-06249728IPR000742
DomainEGF_3

STAB2 MEGF8 STAB1

1.18e-0512723PF12947
DomainEGF_dom

STAB2 MEGF8 STAB1

1.18e-0512723IPR024731
DomainLINK

STAB2 BCAN STAB1

1.53e-0513723SM00445
DomainLink_dom

STAB2 BCAN STAB1

1.53e-0513723IPR000538
DomainXlink

STAB2 BCAN STAB1

1.53e-0513723PF00193
DomainLINK_1

STAB2 BCAN STAB1

1.53e-0513723PS01241
DomainLINK_2

STAB2 BCAN STAB1

1.53e-0513723PS50963
DomainEGF_3

TPO STAB2 TENM4 MEGF8 TENM3 BCAN STAB1

3.36e-05235727PS50026
DomainRhs_assc_core

TENM4 TENM3

4.39e-053722IPR022385
DomainEGF_1

TPO STAB2 TENM4 MEGF8 TENM3 BCAN STAB1

5.63e-05255727PS00022
DomainEGF-like_CS

TPO STAB2 TENM4 MEGF8 TENM3 BCAN STAB1

6.52e-05261727IPR013032
DomainEGF_2

TPO STAB2 TENM4 MEGF8 TENM3 BCAN STAB1

7.18e-05265727PS01186
DomainEGF_extracell

STAB2 TENM4 TENM3 STAB1

8.41e-0560724IPR013111
DomainEGF_2

STAB2 TENM4 TENM3 STAB1

8.41e-0560724PF07974
DomainTox-GHH_dom

TENM4 TENM3

8.75e-054722IPR028916
DomainFAS1

STAB2 STAB1

8.75e-054722SM00554
DomainFAS1_domain

STAB2 STAB1

8.75e-054722IPR000782
DomainTen_N

TENM4 TENM3

8.75e-054722IPR009471
DomainTen_N

TENM4 TENM3

8.75e-054722PF06484
Domain-

STAB2 STAB1

8.75e-0547222.30.180.10
DomainTENEURIN_N

TENM4 TENM3

8.75e-054722PS51361
DomainFAS1

STAB2 STAB1

8.75e-054722PS50213
DomainFasciclin

STAB2 STAB1

8.75e-054722PF02469
DomainTox-GHH

TENM4 TENM3

8.75e-054722PF15636
DomainYD

TENM4 TENM3

1.45e-045722IPR006530
DomainEGF_LAM_2

STAB2 MEGF8 STAB1

2.07e-0430723PS50027
DomainEGF_LAM_1

STAB2 MEGF8 STAB1

2.07e-0430723PS01248
DomainPSI

MEGF8 PLXNA4 PLXNA2

2.51e-0432723PF01437
DomainPlexin_repeat

MEGF8 PLXNA4 PLXNA2

2.51e-0432723IPR002165
DomainEGF_Lam

STAB2 MEGF8 STAB1

3.29e-0435723SM00180
DomainGrowth_fac_rcpt_

FRAS1 STAB2 IGFBP5 MEGF8 STAB1

3.40e-04156725IPR009030
DomainLaminin_EGF

STAB2 MEGF8 STAB1

4.21e-0438723IPR002049
DomainPlexin_cytopl

PLXNA4 PLXNA2

5.18e-049722PF08337
DomainPlexin_cytoplasmic_RasGAP_dom

PLXNA4 PLXNA2

5.18e-049722IPR013548
DomainPlexin

PLXNA4 PLXNA2

5.18e-049722IPR031148
DomainPSI

MEGF8 PLXNA4 PLXNA2

6.50e-0444723IPR016201
DomainPSI

MEGF8 PLXNA4 PLXNA2

7.40e-0446723SM00423
Domain-

STAB2 STAB1

7.88e-04117222.40.155.10
DomainGFP-like

STAB2 STAB1

7.88e-0411722IPR023413
DomainNHL

TENM4 TENM3

1.11e-0313722PS51125
DomainEGF_CA

TPO STAB2 MEGF8 STAB1

1.27e-03122724SM00179
DomainEGF-like_Ca-bd_dom

TPO STAB2 MEGF8 STAB1

1.34e-03124724IPR001881
DomainCarboxyPept-like_regulatory

TENM4 TENM3

1.92e-0317722IPR008969
Domain-

IGFN1 PIGR FSTL4 PLXNA4 BCAN LILRB1 PLXNA2 MYBPC2

3.91e-036637282.60.40.10
DomainIPT

PLXNA4 PLXNA2

4.83e-0327722SM00429
DomainBTB

KLHL6 KCTD12 KCTD15 ZBTB8A

5.16e-03180724SM00225
DomainIG

IGFN1 PIGR FSTL4 BCAN LILRB1 MYBPC2

5.65e-03421726SM00409
DomainIg_sub

IGFN1 PIGR FSTL4 BCAN LILRB1 MYBPC2

5.65e-03421726IPR003599
DomainBTB/POZ_dom

KLHL6 KCTD12 KCTD15 ZBTB8A

5.68e-03185724IPR000210
DomainIg-like_fold

IGFN1 PIGR FSTL4 PLXNA4 BCAN LILRB1 PLXNA2 MYBPC2

5.69e-03706728IPR013783
DomainSKP1/BTB/POZ

KLHL6 KCTD12 KCTD15 ZBTB8A

6.12e-03189724IPR011333
Domain-

STAB2 BCAN STAB1

6.25e-03977233.10.100.10
DomainTIG

PLXNA4 PLXNA2

6.34e-0331722PF01833
DomainSema

PLXNA4 PLXNA2

6.34e-0331722SM00630
DomainSemap_dom

PLXNA4 PLXNA2

6.34e-0331722IPR001627
DomainSema

PLXNA4 PLXNA2

6.34e-0331722PF01403
DomainSEMA

PLXNA4 PLXNA2

6.34e-0331722PS51004
DomainDEAD_ATP_HELICASE

DDX49 DDX53

6.34e-0331722PS00039
DomainC-type_lectin-like/link

STAB2 BCAN STAB1

6.61e-0399723IPR016186
DomainIPT

PLXNA4 PLXNA2

6.75e-0332722IPR002909
DomainRNA-helicase_DEAD-box_CS

DDX49 DDX53

7.16e-0333722IPR000629
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_COMPLEMENT_CASCADE_CFHR

CFH CFHR1 CFHR2

1.05e-066543M47880
Pubmed

Atypical haemolytic-uraemic syndrome due to heterozygous mutations of CFH/CFHR1-3 and complement factor H 479.

CFH CFHR1 CFHR2

3.69e-08474324333077
Pubmed

Complement factor H and related proteins: an expanding family of complement-regulatory proteins?

CFH CFHR1 CFHR2

9.22e-0857438172644
Pubmed

Identification and sequence analysis of four complement factor H-related transcripts in mouse liver.

CFH CFHR1 CFHR2

9.22e-0857431689298
Pubmed

A radiation hybrid map of complement factor H and factor H-related genes.

CFH CFHR1 CFHR2

9.22e-08574310380701
Pubmed

Dimerization of complement factor H-related proteins modulates complement activation in vivo.

CFH CFHR1 CFHR2

1.84e-07674323487775
Pubmed

Sequence and Expression of Complement Factor H Gene Cluster Variants and Their Roles in Age-Related Macular Degeneration Risk.

CFH CFHR1 CFHR2

1.84e-07674327196323
Pubmed

Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: characterization, ethnic distribution and evolutionary implications.

CFH CFHR1 CFHR2

1.84e-07674317438673
Pubmed

Epidemiological approach to identifying genetic predispositions for atypical hemolytic uremic syndrome.

CFH CFHR1 CFHR2

7.70e-07974320059470
Pubmed

Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development.

TENM4 TENM3 ADGRL3

1.10e-061074338713721
Pubmed

The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map.

STAB2 TENM3 PLXNA4 BCAN DCT

1.80e-069474523431145
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FRAS1 TENM4 MEGF8 TENM3 IST1 ADCY3 PLXNA2 ADGRL3

2.52e-0640774812693553
Pubmed

Functional assembly of accessory optic system circuitry critical for compensatory eye movements.

FSTL4 PLXNA4 PLXNA2

2.60e-061374325959730
Pubmed

Deregulation of Factor H by Factor H-Related Protein 1 Depends on Sialylation of Host Surfaces.

CFH CFHR1

4.47e-06274233732239
Pubmed

Deficiency of Mouse FHR-1 Homolog, FHR-E, Accelerates Sepsis, and Acute Kidney Injury Through Enhancing the LPS-Induced Alternative Complement Pathway.

CFHR1 CFHR2

4.47e-06274232636836
Pubmed

FEEL-1 and FEEL-2 are endocytic receptors for advanced glycation end products.

STAB2 STAB1

4.47e-06274212473645
Pubmed

Identifying Stabilin-1 and Stabilin-2 Double Knockouts in Reproduction and Placentation: A Descriptive Study.

STAB2 STAB1

4.47e-06274233008099
Pubmed

Molecular cloning of a human serum protein structurally related to complement factor H.

CFHR1 CFHR2

4.47e-0627421711047
Pubmed

Interaction between complement regulators and Streptococcus pyogenes: binding of C4b-binding protein and factor H/factor H-like protein 1 to M18 strains involves two different cell surface molecules.

CFH CFHR1

4.47e-06274215557185
Pubmed

Exploring the transcriptomic network of multi-ligand scavenger receptor Stabilin-1- and Stabilin-2-deficient liver sinusoidal endothelial cells.

STAB2 STAB1

4.47e-06274233130055
Pubmed

Factor H-related protein 1 neutralizes anti-factor H autoantibodies in autoimmune hemolytic uremic syndrome.

CFH CFHR1

4.47e-06274221677636
Pubmed

Factor H and CFHR1 polymorphisms associated with atypical Haemolytic Uraemic Syndrome (aHUS) are differently expressed in Tunisian and in Caucasian populations.

CFH CFHR1

4.47e-06274222136554
Pubmed

Deciphering the ligand-binding sites in the Borrelia burgdorferi complement regulator-acquiring surface protein 2 required for interactions with the human immune regulators factor H and factor H-like protein 1.

CFH CFHR1

4.47e-06274218824548
Pubmed

Teneurins assemble into presynaptic nanoclusters that promote synapse formation via postsynaptic non-teneurin ligands.

TENM4 TENM3

4.47e-06274235484136
Pubmed

Molecular bases for the association of FHR-1 with atypical hemolytic uremic syndrome and other diseases.

CFHR1 CFHR2

4.47e-06274233651882
Pubmed

Anti-factor H autoantibody-associated hemolytic uremic syndrome: review of literature of the autoimmune form of HUS.

CFH CFHR1

4.47e-06274220865640
Pubmed

A synthetic protein as efficient multitarget regulator against complement over-activation.

CFH CFHR1

4.47e-06274235194132
Pubmed

Complement factor H-related protein 1 deficiency and factor H antibodies in pediatric patients with atypical hemolytic uremic syndrome.

CFH CFHR1

4.47e-06274223243267
Pubmed

Cloning of the 1.4-kb mRNA species of human complement factor H reveals a novel member of the short consensus repeat family related to the carboxy terminal of the classical 150-kDa molecule.

CFH CFHR1

4.47e-0627421826708
Pubmed

Mechanism for phosphatidylserine-dependent erythrophagocytosis in mouse liver.

STAB2 STAB1

4.47e-06274221427291
Pubmed

Factor H autoantibodies and deletion of Complement Factor H-Related protein-1 in rheumatic diseases in comparison to atypical hemolytic uremic syndrome.

CFH CFHR1

4.47e-06274222894814
Pubmed

Deficiency of liver sinusoidal scavenger receptors stabilin-1 and -2 in mice causes glomerulofibrotic nephropathy via impaired hepatic clearance of noxious blood factors.

STAB2 STAB1

4.47e-06274221293057
Pubmed

Human complement factor H and factor H-like protein 1 are expressed in human retinal pigment epithelial cells.

CFH CFHR1

4.47e-06274224280833
Pubmed

A novel hybrid CFHR1/CFH gene causes atypical hemolytic uremic syndrome.

CFH CFHR1

4.47e-06274223880784
Pubmed

Binding of the human complement regulators CFHR1 and factor H by streptococcal collagen-like protein 1 (Scl1) via their conserved C termini allows control of the complement cascade at multiple levels.

CFH CFHR1

4.47e-06274220855886
Pubmed

Stabilin-1 and stabilin-2 are both directed into the early endocytic pathway in hepatic sinusoidal endothelium via interactions with clathrin/AP-2, independent of ligand binding.

STAB2 STAB1

4.47e-06274215572036
Pubmed

Phenotypical and biochemical characterization of murine psoriasiform and fibrotic skin disease models in Stabilin-deficient mice.

STAB2 STAB1

4.47e-06274238946049
Pubmed

Stabilin-1 and -2 constitute a novel family of fasciclin-like hyaluronan receptor homologues.

STAB2 STAB1

4.47e-06274211829752
Pubmed

Complement factor H: a biomarker for progression of cutaneous squamous cell carcinoma.

CFH CFHR1

4.47e-06274223938460
Pubmed

FEEL-1, a novel scavenger receptor with in vitro bacteria-binding and angiogenesis-modulating activities.

STAB2 STAB1

4.47e-06274212077138
Pubmed

Genetic influences on plasma CFH and CFHR1 concentrations and their role in susceptibility to age-related macular degeneration.

CFH CFHR1

4.47e-06274223873044
Pubmed

Teneurin-3 controls topographic circuit assembly in the hippocampus.

TENM3 ADGRL3

4.47e-06274229414938
Pubmed

CFH-CFHR1 hybrid genes in two cases of atypical hemolytic uremic syndrome.

CFH CFHR1

4.47e-06274236755127
Pubmed

Association of Differentially Altered Liver Fibrosis with Deposition of TGFBi in Stabilin-Deficient Mice.

STAB2 STAB1

4.47e-06274237446152
Pubmed

The major autoantibody epitope on factor H in atypical hemolytic uremic syndrome is structurally different from its homologous site in factor H-related protein 1, supporting a novel model for induction of autoimmunity in this disease.

CFH CFHR1

4.47e-06274225659429
Pubmed

Scavenging Endothelium of Pancreatic Islets: Differential Expression of Stabilin-1 and Stabilin-2 in Mice and Humans.

STAB2 STAB1

4.47e-06274227977633
Pubmed

Associations of CFHR1-CFHR3 deletion and a CFH SNP to age-related macular degeneration are not independent.

CFH CFHR1

1.34e-05374220581873
Pubmed

Structural Basis for Plexin Activation and Regulation.

PLXNA4 PLXNA2

1.34e-05374227397516
Pubmed

Complement factor H, FHR-3 and FHR-1 variants associate in an extended haplotype conferring increased risk of atypical hemolytic uremic syndrome.

CFH CFHR1

1.34e-05374226163426
Pubmed

Complement factor H: sequence analysis of 221 kb of human genomic DNA containing the entire fH, fHR-1 and fHR-3 genes.

CFH CFHR1

1.34e-05374210781834
Pubmed

Interactions between plexin-A2, plexin-A4, and semaphorin 6A control lamina-restricted projection of hippocampal mossy fibers.

PLXNA4 PLXNA2

1.34e-05374217296555
Pubmed

Dihydrolipoamide dehydrogenase of Pseudomonas aeruginosa is a surface-exposed immune evasion protein that binds three members of the factor H family and plasminogen.

CFH CFHR1

1.34e-05374223071278
Pubmed

Highly oxidized albumin is cleared by liver sinusoidal endothelial cells via the receptors stabilin-1 and -2.

STAB2 STAB1

1.34e-05374237926735
Pubmed

Association assessment of copy number polymorphism and risk of age-related macular degeneration.

CFH CFHR1

1.34e-05374221856016
Pubmed

Variants in Complement Factor H and Complement Factor H-Related Protein Genes, CFHR3 and CFHR1, Affect Complement Activation in IgA Nephropathy.

CFH CFHR1

1.34e-05374225205734
Pubmed

Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells.

PLXNA4 PLXNA2

1.34e-05374218625214
Pubmed

Factor H autoantibodies in atypical hemolytic uremic syndrome correlate with CFHR1/CFHR3 deficiency.

CFH CFHR1

1.34e-05374218006700
Pubmed

Serum FHR1 binding to necrotic-type cells activates monocytic inflammasome and marks necrotic sites in vasculopathies.

CFHR1 CFHR2

1.34e-05374231273197
Pubmed

Stabilin receptors clear LPS and control systemic inflammation.

STAB2 STAB1

1.34e-05374234816100
Pubmed

Atypical hemolytic uremic syndrome associated with complement factor H autoantibodies and CFHR1/CFHR3 deficiency.

CFH CFHR1

1.34e-05374219531976
Pubmed

Role of transmembrane semaphorin Sema6A in oligodendrocyte differentiation and myelination.

PLXNA4 PLXNA2

1.34e-05374222777942
Pubmed

Borrelia recurrentis employs a novel multifunctional surface protein with anti-complement, anti-opsonic and invasive potential to escape innate immunity.

CFH CFHR1

1.34e-05374219308255
Pubmed

Evaluation of CFH Y402H polymorphism and CFHR3/CFHR1 deletion in age-related macular degeneration patients from Brazil.

CFH CFHR1

1.34e-05374226942649
Pubmed

An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD).

CFH CFHR1

1.34e-05374220843825
Pubmed

Associations of CFH polymorphisms and CFHR1-CFHR3 deletion with blood pressure and hypertension in Chinese population.

CFH CFHR1

1.34e-05374222848687
Pubmed

A genome-wide association study identifies key modulators of complement factor H binding to malondialdehyde-epitopes.

CFH CFHR1

1.34e-05374232321835
Pubmed

Atypical hemolytic uremic syndrome-associated variants and autoantibodies impair binding of factor h and factor h-related protein 1 to pentraxin 3.

CFH CFHR1

1.34e-05374222786770
Pubmed

Factor H and factor H-related protein 1 bind to human neutrophils via complement receptor 3, mediate attachment to Candida albicans, and enhance neutrophil antimicrobial activity.

CFH CFHR1

1.34e-05374220008295
Pubmed

C3 glomerulopathy-associated CFHR1 mutation alters FHR oligomerization and complement regulation.

CFHR1 CFHR2

1.34e-05374223728178
Pubmed

The opportunistic human pathogenic fungus Aspergillus fumigatus evades the host complement system.

CFH CFHR1

1.34e-05374218039838
Pubmed

BMP type I receptor ALK2 is required for angiotensin II-induced cardiac hypertrophy.

BMPR1A A1CF

2.67e-05474226873969
Pubmed

Mouse ten-m/Odz is a new family of dimeric type II transmembrane proteins expressed in many tissues.

TENM4 TENM3

2.67e-05474210225957
Pubmed

Plasma lipopolysaccharide-binding protein is found associated with a particle containing apolipoprotein A-I, phospholipid, and factor H-related proteins.

CFH CFHR1

2.67e-0547428663389
Pubmed

Chromosome assignment of four plexin A genes (Plxna1, Plxna2, Plxna3, Plxna4) in mouse, rat, Syrian hamster and Chinese hamster.

PLXNA4 PLXNA2

2.67e-05474211306810
Pubmed

PlexinA polymorphisms mediate the developmental trajectory of human corpus callosum microstructure.

PLXNA4 PLXNA2

2.67e-05474225518740
Pubmed

CFH and CFHR structural variants in atypical Hemolytic Uremic Syndrome: Prevalence, genomic characterization and impact on outcome.

CFH CFHR1

2.67e-05474236793547
Pubmed

All four members of the Ten-m/Odz family of transmembrane proteins form dimers.

TENM4 TENM3

2.67e-05474212000766
Pubmed

Targeting of Scavenger Receptors Stabilin-1 and Stabilin-2 Ameliorates Atherosclerosis by a Plasma Proteome Switch Mediating Monocyte/Macrophage Suppression.

STAB2 STAB1

2.67e-05474236325910
Pubmed

Deficiency for scavenger receptors Stabilin-1 and Stabilin-2 leads to age-dependent renal and hepatic depositions of fasciclin domain proteins TGFBI and Periostin in mice.

STAB2 STAB1

2.67e-05474237357460
Pubmed

Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease.

CFH KAZN PLXNA2

2.92e-052874333953184
Pubmed

A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.

TENM4 IGFBP5 TENM3 PLXNA2

4.39e-059174428558017
Pubmed

Factor H-related proteins determine complement-activating surfaces.

CFHR1 CFHR2

4.45e-05574225979655
Pubmed

Guidance-cue control of horizontal cell morphology, lamination, and synapse formation in the mammalian outer retina.

PLXNA4 PLXNA2

4.45e-05574222593055
Pubmed

Comparison of the four mouse fasciclin-containing genes expression patterns during valvuloseptal morphogenesis.

STAB2 STAB1

4.45e-05574215907457
Pubmed

The DNA sequence and biological annotation of human chromosome 1.

CFH CFHR1 CFHR2 GPR61 MARK1 ZBTB8A PLA2G5 KAZN AP4B1 SH2D5

6.47e-051031741016710414
Pubmed

Semaphorin-Plexin signaling influences early ventral telencephalic development and thalamocortical axon guidance.

PLXNA4 PLXNA2

6.66e-05674228438183
Pubmed

Roles of semaphorin-6B and plexin-A2 in lamina-restricted projection of hippocampal mossy fibers.

PLXNA4 PLXNA2

6.66e-05674220484647
Pubmed

The NEI/NCBI dbGAP database: genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degeneration.

CFH CFHR2

6.66e-05674218541031
Pubmed

Growth of geographic atrophy on fundus autofluorescence and polymorphisms of CFH, CFB, C3, FHR1-3, and ARMS2 in age-related macular degeneration.

CFH CFHR1

6.66e-05674224557084
Pubmed

Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice points.

PLXNA4 PLXNA2

9.31e-05774219063725
Pubmed

Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice.

PLXNA4 PLXNA2

9.31e-05774219655386
Pubmed

Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical hemolytic uremic syndrome.

CFH CFHR1

9.31e-05774219861685
Pubmed

The mammalian Odz gene family: homologs of a Drosophila pair-rule gene with expression implying distinct yet overlapping developmental roles.

TENM4 TENM3

9.31e-05774210625539
Pubmed

The murine Ten-m/Odz genes show distinct but overlapping expression patterns during development and in adult brain.

TENM4 TENM3

9.31e-05774212915301
Pubmed

The expression of plexins during mouse embryogenesis.

PLXNA4 PLXNA2

1.24e-04874215661641
Pubmed

Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production.

RTP1 ADCY3

1.24e-04874235025664
Pubmed

C3 Glomerulopathy

CFH CFHR1

1.24e-04874220301598
Pubmed

Mapping homologs of Drosophila odd Oz (odz): Doc4/Odz4 to mouse chromosome 7, Odz1 to mouse chromosome 11; and ODZ3 to human chromosome Xq25.

TENM4 TENM3

1.24e-04874210331952
Pubmed

Integration of opposing semaphorin guidance cues in cortical axons.

PLXNA4 PLXNA2

1.24e-04874222368082
Pubmed

The BTB domains of the potassium channel tetramerization domain proteins prevalently assume pentameric states.

KCTD12 KCTD15

1.24e-04874227152988
Pubmed

KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2.

PIGR KCTD15

1.59e-04974231685809
InteractionCFHR1 interactions

CFH CFHR1 CFHR2

1.45e-067713int:CFHR1
CytobandEnsembl 112 genes in cytogenetic band chr1q31

CFH CFHR1 CFHR2

2.50e-0475743chr1q31
Cytoband3q27.3

KLHL6 RTP1

3.86e-04187423q27.3
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CFH TPO CFHR1 CFHR2 BCAN

4.47e-07574951179
GeneFamilyComplement system|Sushi domain containing

CFH CFHR1 CFHR2

1.25e-0436493492
GeneFamilyPlexins

PLXNA4 PLXNA2

2.56e-049492683
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

STAB2 STAB1

2.42e-03274921253
GeneFamilyDEAD-box helicases

DDX49 DDX53

5.78e-0342492499
GeneFamilyPhospholipases

PLA2G5 PLA2G4D

5.78e-0342492467
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

IGFN1 FSTL4 MYBPC2

9.46e-03161493593
GeneFamilyEF-hand domain containing

DST CAPN1 FSTL4

2.15e-02219493863
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_200

TENM4 IGFBP5 TENM3 PLXNA4 DCT WNK3 ADGRL3

1.41e-06162737gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_200
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#3_top-relative-expression-ranked_500

PLXNA4 DCT WNK3 ADGRL3

5.07e-0559734gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k3_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_1000

FRAS1 TENM4 IGFBP5 TENM3 PLXNA4 ADGRL3

6.35e-05199736gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k1_1000
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFH KCTD12 CFHR2 P2RY6 MPEG1 STAB1

4.73e-0717574653e6f1f8dd482dfa2539e068dacefbb6e08443bc
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 IGFN1 STAB2 LOXHD1 TENM4 ADGRL3

6.34e-071847462cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 IGFN1 STAB2 LOXHD1 TENM4 ADGRL3

6.34e-07184746ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 IGFN1 STAB2 LOXHD1 TENM4 ADGRL3

6.34e-071847462b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NAPSA TENM4 PIGR KAZN PLEKHA7 PLXNA2

6.75e-07186746e83718fabb057100835d3357df407f283d23fe16
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

FRAS1 DST TENM3 PLXNA4 KAZN ADGRL3

8.90e-07195746603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

CFH FRAS1 DST TENM3 PLXNA4 KAZN

9.73e-07198746df3de77216f5c5d6141ec44d01c56b942f611838
ToppCellTracheal-NucSeq-Immune_Myeloid|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KLHL6 P2RY6 DOCK11 MPEG1 LILRB1 STAB1

1.03e-06200746ad7ae5106141669b353800fece833b3cd5bdccee
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NAPSA PIGR KAZN PLXNA2 WNK3

2.86e-061337455bf5e654653e2c340891f51e3f2a30441b7b6b2b
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA GCNT3 MPEG1 DMBT1 ADGRL3

7.06e-06160745e9e52532131cdc3fb01e81cfc046e3f670cc8e75
ToppCellLV-11._Adipocyte|World / Chamber and Cluster_Paper

TENM4 TENM3 DOCK11 PLXNA4 GYG2

8.44e-061667457e5852891714465c6228c9f955fd511ec79d0e02
ToppCellfacs-Heart-LA-18m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GCNT3 PIGR P2RY6 MPEG1 DMBT1

8.44e-0616674519ec59f0a43d4eb5b4cc7bcd6480ada7f469054b
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFH KCTD12 P2RY6 MPEG1 STAB1

9.47e-061707456ec0cf055ae55e9fac147f7989c47f83ab07270c
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFH KCTD12 P2RY6 MPEG1 STAB1

1.00e-05172745c96bd3407911df3e3e6d7a3dba786b11814b9598
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFH KCTD12 P2RY6 MPEG1 STAB1

1.00e-05172745f0e767a20d93e546ce278db67dbd779cc68af533
ToppCellLV-11._Adipocyte|LV / Chamber and Cluster_Paper

TENM4 TENM3 DOCK11 PLXNA4 GYG2

1.03e-05173745c2d3fcb3de71015d03d14c63450853d2b03ffa71
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFH KCTD12 P2RY6 MPEG1 STAB1

1.06e-05174745f520b79d277e286c9bb5d091e6c94e7ec7e46699
ToppCellB_cells-pDCs|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

KCTD12 DST P2RY6 PLXNA4 MPEG1

1.12e-05176745ce757de9e09a225f3f96433f103f43619b0e0dda
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-IM|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFH KCTD12 P2RY6 MPEG1 STAB1

1.12e-05176745adb679e69c0c17f0caee4c141bac55d03c963012
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFH KCTD12 P2RY6 MPEG1 STAB1

1.15e-05177745ab92ffc9624850a50c88e6b8f3a517ff2251ff15
ToppCellRV-11._Adipocyte|World / Chamber and Cluster_Paper

TENM4 TENM3 DOCK11 PLXNA4 GYG2

1.15e-05177745f0edf04930692418953e4f00a917257804ec0ffd
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Myeloid-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA DDX49 P2RY6 ANKRD61 MPEG1

1.18e-05178745ee674e379ee57e40eb2560ff5ed4c13d8db7ed9d
ToppCellRV-11._Adipocyte|RV / Chamber and Cluster_Paper

TENM4 TENM3 DOCK11 PLXNA4 GYG2

1.18e-05178745278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Myeloid|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA DDX49 P2RY6 ANKRD61 MPEG1

1.18e-051787456c45bf197d6c1be0ef7d3a644c0062acf1e24e4d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Myeloid-macrophage|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA DDX49 P2RY6 ANKRD61 MPEG1

1.18e-05178745cd85dcefe94ee742db64b63e105e13532321894a
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NAPSA TENM4 PIGR KAZN PLEKHA7

1.22e-05179745fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFH FRAS1 PIGR PLXNA4 GYG2

1.25e-05180745b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid-Macrophages|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCTD12 P2RY6 MPEG1 LILRB1 STAB1

1.25e-051807457af90f0e7ca001bf1fe5c860ee54c4cc8eb483bf
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFH KCTD12 P2RY6 MPEG1 STAB1

1.25e-05180745a600bc705993d3a010550a25d3b54358946f061f
ToppCell5'-Adult-Appendix-Neuronal-Glial_mature|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FRAS1 TENM4 TENM3 BCAN ADGRL3

1.28e-051817453aa81ac64d0cc9a74fbfa71e2176740548e7cd06
ToppCell5'-Adult-Appendix-Neuronal-Glial_mature-Adult_Glia|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FRAS1 TENM4 TENM3 BCAN ADGRL3

1.28e-05181745997ba1be2824b00d684f2163d0114656ed11fa53
ToppCellCOVID-19-Heart-Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRPA1 MARK1 PLA2G5 ADCY3 ADGRL3

1.28e-0518174533cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KLHL6 P2RY6 MPEG1 LILRB1 STAB1

1.28e-05181745090e89b506d945e123e647d08947e9649a65ce7c
ToppCell5'-Adult-Appendix-Neuronal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FRAS1 TENM4 TENM3 BCAN ADGRL3

1.28e-05181745e6b7e8dd5c13cc10ba22f2f5a8c669486f934bdc
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFH TENM4 MARK1 PLXNA4 PFKP

1.32e-05182745ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

TPO TENM4 TRPA1 PLA2G5 ADGRL3

1.32e-05182745fbd5e332df73bf7141c822fa67b76367dc962017
ToppCellLA-11._Adipocyte|World / Chamber and Cluster_Paper

TENM4 TENM3 DOCK11 PLXNA4 GYG2

1.35e-05183745b177be283e1553fb1f69a346f1ba79ad00297fa2
ToppCellLA-11._Adipocyte|LA / Chamber and Cluster_Paper

TENM4 TENM3 DOCK11 PLXNA4 GYG2

1.35e-051837453f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P2-Tnr|Thalamus / BrainAtlas - Mouse McCarroll V32

PLA2G5 PLA2G4D DCT EDA2R

1.35e-05877440c3a3ed1f279ed29a0113cc73ae590157a4b7334
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4_(Bmp4)-|Thalamus / BrainAtlas - Mouse McCarroll V32

PLA2G5 PLA2G4D DCT EDA2R

1.35e-05877445d1dbbd86d82cbce4f2a3365242eb92d9c821a9e
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P2|Thalamus / BrainAtlas - Mouse McCarroll V32

PLA2G5 PLA2G4D DCT EDA2R

1.35e-0587744a93dbe73b337cc2d93208822728b9badf30b6870
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4_(Bmp4)|Thalamus / BrainAtlas - Mouse McCarroll V32

PLA2G5 PLA2G4D DCT EDA2R

1.35e-058774445ef27ba84f731e4b2188813cd6931950e5164ac
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KCTD12 TENM4 DST IGFBP5 PLXNA2

1.43e-051857451ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCellfacs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAPSA KCTD12 P2RY6 MPEG1 PFKP

1.43e-05185745ed7b26bdebfd0df2b4f5020a855a052d94ae7219
ToppCellnormal_Lymph_Node-Myeloid_cells-mo-Mac|normal_Lymph_Node / Location, Cell class and cell subclass

KCTD12 DST P2RY6 MPEG1 STAB1

1.54e-05188745e83de94a9b47a6a90e98face887eae031a322af6
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NAPSA TENM4 PIGR KAZN PLEKHA7

1.54e-051887454bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCellAdult-Epithelial-club_cell|Adult / Lineage, Cell type, age group and donor

CFH FRAS1 PIGR P2RY6 PLXNA4

1.62e-05190745756bff697d30aec56c0ebfca94295f084a15bf37
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

CFH MARK1 PLA2G5 ADCY3 ADGRL3

1.66e-0519174578c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCellfacs-Brain_Myeloid|facs / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH KCTD12 P2RY6 MPEG1 STAB1

1.66e-05191745bf1135b382a3bf8cddc19538bc38361ef1fc2de1
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TENM4 IGFBP5 TENM3 KAZN ADGRL3

1.70e-05192745d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCellfacs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAPSA KCTD12 P2RY6 MPEG1 PFKP

1.70e-051927458b4bbbadeac70f65378697120c754f10501b5651
ToppCell10x5'-bone_marrow-Myeloid_Dendritic|bone_marrow / Manually curated celltypes from each tissue

NAPSA DST P2RY6 PLXNA4 MPEG1

1.79e-05194745768271ae45ff9f6aa3cd9b0ed15fa3caaa68a7b0
ToppCelldroplet-Bladder-nan-3m-Epithelial-basal_bladder_epithelial_cell_(Krt5+Krt14+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST IGFBP5 CAPN1 ECI1 SH2D5

1.79e-0519474537803f4abf1aa1ad771c9cd293933003d7101e70
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_dendritic_(11)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KLHL6 P2RY6 MPEG1 LILRB1 STAB1

1.84e-051957454387e27d2288fb46a9ed110464542a4aea402358
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

CFH TENM4 PLA2G5 KAZN ADGRL3

1.84e-05195745f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NAPSA KCTD12 DST P2RY6 PLXNA4

1.84e-051957454cbc36fb3ef9aef61367d3b37070a9a85fae1418
ToppCellASK428-Epithelial-Transformed_epithelium|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

CFH IGFBP5 DOCK11 PLXNA4 ADCY3

1.84e-05195745c750602c765a51075ba6ede78e3ba80b62374481
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

KCTD12 FRAS1 DST PLA2G5 KAZN

1.88e-051967456730743cf088c419ccc2d28765769fc09d3ba6a7
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

KCTD12 FRAS1 DST PLA2G5 KAZN

1.88e-0519674521dab89f3699037138a9c7a0e4dc98739a9fad9c
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Dendritic|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NAPSA KCTD12 DST P2RY6 MPEG1

1.93e-0519774589fe4885efc8db142c0dc0506840ae8aceba9ef9
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

CFH TENM4 DST TENM3 KAZN

1.93e-05197745f1c8936986123a3151140c374fcd62d6705c530b
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 GCNT3 RHPN2 KAZN PLEKHA7

1.93e-051977457e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCellMild-Myeloid-Macrophages-FCN1_high|Mild / Condition, Lineage, Cell class and cell subclass

KCTD12 P2RY6 MPEG1 LILRB1 STAB1

1.98e-0519874517aab4dc3b2cd6eb7dda77dd51bdc20490fcfe19
ToppCellParenchymal-10x3prime_v2-Stromal-Mesofibroblastic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CFH TENM4 IGFBP5 TENM3 P2RY6

1.98e-051987450cd930e374c2c48d1991b51c025f9801b22ecee7
ToppCellParenchymal-10x3prime_v2-Stromal-Mesofibroblastic-Mesothelia|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CFH TENM4 IGFBP5 TENM3 P2RY6

1.98e-05198745e0df6d6ff2a9c41d813f84a2a5ee7cb5f6fc3e30
ToppCell3'_v3-GI_small-bowel-Myeloid_Mac|GI_small-bowel / Manually curated celltypes from each tissue

KCTD12 DST P2RY6 MPEG1 STAB1

2.02e-051997458990a3d69e24cb3aaba9d6def3d0be9ee973436d
ToppCell3'_v3-GI_small-bowel-Myeloid_Mac-Intestinal_macrophages|GI_small-bowel / Manually curated celltypes from each tissue

KCTD12 DST P2RY6 MPEG1 STAB1

2.02e-0519974596070b5ffcbab4952970f43b536969ddd2ca5d14
ToppCellASK452-Epithelial|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

CFH NAPSA DST PIGR DMBT1

2.02e-05199745e8778d4d2bc7e15b4c7989a93e5808a76738df46
ToppCellCaecum-(5)_Dendritic_cell-(51)_cDC1|Caecum / shred on region, Cell_type, and subtype

DST P2RY6 MPEG1 ADCY3 EDA2R

2.02e-051997452b97fda45241b2ce7be904cf081cabcf3eb5ba1d
ToppCellCaecum-Dendritic_cell-cDC1|Caecum / Region, Cell class and subclass

DST P2RY6 MPEG1 ADCY3 EDA2R

2.02e-051997459ab38a0060a883de6fe3da8cdac42e124d7981d9
ToppCellILEUM-inflamed-(8)_Fibroblast-(8)_Fibroblasts|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CFH KCTD12 DST IGFBP5 ADGRL3

2.02e-05199745615f20bf136dfef53b072667cf0e4df6a1017e05
ToppCellParenchymal-10x5prime-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFH CFHR1 IGFBP5 ADCY3 ADGRL3

2.07e-0520074538190e4b32f7469df1da7d130bca6d7b12a3dd06
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFHR1 IGFN1 IGFBP5 ADCY3 ADGRL3

2.07e-05200745fc2fc3bfcf1ad9bfb9fe07bbed8068126930bee6
ToppCellsevere-CD163+_Monocytes_(Sample_ID1_d7)|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

KCTD12 P2RY6 MPEG1 LILRB1 STAB1

2.07e-052007454943fe826d5fcc3dfeb8b99a7415848f3fecc994
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_monocytic-monocyte|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KCTD12 TENM4 MPEG1 PLEKHA7

5.62e-05125744a72891c3fb9cdefa9254f8e2e3c4ffa6fc3a5ffc
ToppCellE16.5-samps-Myeloid-Macrophage|E16.5-samps / Age Group, Lineage, Cell class and subclass

CFHR2 P2RY6 MPEG1 SH2D5

1.08e-04148744cd5f697d8c2f272be1f3f52a05446749278431c5
ToppCellE16.5-samps-Myeloid-Macrophage-CD163+_Macrophage|E16.5-samps / Age Group, Lineage, Cell class and subclass

CFHR2 P2RY6 MPEG1 SH2D5

1.08e-0414874456e146980a71b5ca655118ae13310c5949220d4a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CFH STAB2 TENM3 DDX53

1.11e-04149744cc6224c6b79f43b97adc1ce48ca4906bff2ad318
ToppCellPND07-Immune-Immune_Myeloid-DC-cDC2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KCTD12 IGFN1 P2RY6 LILRB1

1.11e-0414974432e0be7da42d26956683b21a1e7ae6915e4c16fb
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CFH STAB2 TENM3 DDX53

1.11e-0414974424a7538b54b2a5291503c7493fefed4e45e8d710
ToppCelldroplet-Liver-nan-3m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH CFHR1 CFHR2 PIGR

1.17e-04151744cc9632b58522e2ba3ad36a0b8d37c7c9c8b636c4
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

GPR61 P2RY6 DCT LILRB1

1.26e-04154744ea5d0da5dd8ccfc19969aec35f044db77d589f54
ToppCelldroplet-Fat-SCAT-30m-Myeloid|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH KCTD12 DOCK11 MPEG1

1.26e-0415474473de626b210ec5482ba89a65e784c1e77ff2894e
ToppCelldroplet-Fat-SCAT-30m-Myeloid-myeloid_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH KCTD12 DOCK11 MPEG1

1.26e-0415474456fe9953e58f71626d3ddf63d340ed35dfc4ce9f
ToppCellprimary_visual_cortex-Non-neuronal-macrophage-Macrophage-Microglia_Siglech|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CFH P2RY6 MPEG1 STAB1

1.29e-04155744f59ca572556c17c606604da1b0331710d4751e54
ToppCellprimary_visual_cortex-Non-neuronal-macrophage-Macrophage|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CFH P2RY6 MPEG1 STAB1

1.32e-041567444b6b59a1638a7218a9ed9bd702c04d9f51dbc7aa
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFHR1 TENM4 DST P2RY6

1.32e-04156744841d653d74c4de41d2f9a114f6ccb92d6a1ebc24
ToppCelldroplet-Kidney-KIDNEY-30m-Myeloid-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH P2RY6 MPEG1 DMBT1

1.32e-041567446e60e860603a7e8194f437a574ff8e887f6083b8
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CFHR1 TENM4 DST P2RY6

1.32e-04156744a917b3e799a7b2a3c7f36af61f2b69292c0fb5c0
ToppCellprimary_visual_cortex-Non-neuronal-macrophage|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CFH P2RY6 MPEG1 STAB1

1.32e-0415674460a8a8584d3c80c4ceb433cb820de914e33e3500
ToppCellfacs-Marrow-B-cells-24m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH TENM3 P2RY6 MPEG1

1.36e-041577440966e347f8d32b13f8a3b3afba3f64637c69cdf9
ToppCellfacs-Marrow-B-cells-24m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH TENM3 P2RY6 MPEG1

1.36e-041577446ebfedd91d62c6d4aa8f046657a899a279f82ba2
ToppCelldroplet-Bladder-Unstain-18m-Hematologic-macrophage|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCTD12 P2RY6 MPEG1 STAB1

1.39e-04158744e5e7b2d609973f1dd4fe7dc62bb69422268ea801
ToppCelldroplet-Lung-3m-Hematologic-myeloid-interstitial_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCTD12 P2RY6 MPEG1 STAB1

1.39e-041587449a6d9b541446a6aa9f8ed040b330dbb5c6447076
ToppCelldroplet-Lung-3m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCTD12 P2RY6 MPEG1 STAB1

1.39e-041587442438713d2a7e32c647ab3384237ed614f4ec8fec
ToppCellfrontal_cortex-Non-neuronal-macrophage-Macrophage-Microglia_Siglech|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CFH P2RY6 MPEG1 STAB1

1.46e-04160744c3f2f362e5d0602bb997e8367b4c9a8fe88e4ea8
ToppCellfacs-Heart-RV-24m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPA1 PLA2G4D PLEKHA7 SH2D5

1.46e-0416074441d6c811c445c0ba9b6a2deb10a3b6b793172582
ToppCellfacs-Heart-RV-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPA1 PLA2G4D PLEKHA7 SH2D5

1.46e-04160744c1d03c0ac9c12615a06499209fcdf18e9b6f1fba
ToppCellmild-Myeloid-CD14_Monocytes_3|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KCTD12 GCNT3 LILRB1 STAB1

1.46e-04160744a83568cd8a0b05642bacd43a8ec443e5ce314c4d
ToppCellICU-SEP-Myeloid-cDC1|ICU-SEP / Disease, Lineage and Cell Type

CFHR1 DST P2RY6 ZNF318

1.50e-041617449fb73909fc2ec99f96ca2eed1a053bce89de7d16
DiseaseL lactate dehydrogenase measurement

CFH TENM4 NUP160 STAB1

4.17e-0726704EFO_0004808
DiseaseC3 glomerulopathy

CFH CFHR1 CFHR2

1.06e-069703C4087273
Diseasepleckstrin homology domain-containing family A member 7 measurement

CFH PLEKHA7

5.55e-062702EFO_0801891
Diseasecomplement factor H-related protein 4 measurement

CFH TPO CFHR1 CFHR2

5.68e-0649704EFO_0600091
Diseaseanaphase-promoting complex subunit 7 measurement

CFH CFHR1

1.66e-053702EFO_0801381
DiseaseHEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 1

CFH CFHR1

1.66e-053702C2749604
DiseaseHEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 1

CFH CFHR1

1.66e-053702235400
Diseasecalnexin measurement

CFH CFHR1

1.66e-053702EFO_0801444
Diseasecomplement factor H-related protein 4A measurement

CFH CFHR1

1.66e-053702EFO_0600057
DiseaseHemolytic uremic syndrome, atypical, susceptibility to, 1

CFH CFHR1

1.66e-053702cv:C2749604
Diseasebrevican core protein measurement

CFH BCAN

1.66e-053702EFO_0020193
Diseasehistone-lysine N-methyltransferase 2D measurement

CFH CFHR1

1.66e-053702EFO_0801683
DiseaseNADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial measurement

CFH CFHR1

3.32e-054702EFO_0803292
Diseasekallikrein-5 measurement

CFH CFHR1

3.32e-054702EFO_0020515
Diseasecomplement factor H-related protein 2 measurement

CFH CFHR1 CFHR2

4.47e-0529703EFO_0600055
DiseaseAge related macular degeneration

CFH CFHR1 CFHR2

4.96e-0530703C0242383
DiseaseComplement deficiency disease

CFH CFHR1 CFHR2

6.63e-0533703C0272242
DiseaseMembranoproliferative Glomerulonephritis, Type II

CFH CFHR1

8.27e-056702C0268743
Diseasecomplement C1s subcomponent measurement

CFH CFHR1

8.27e-056702EFO_0008091
Diseasepleckstrin homology domain-containing family A member 1 measurement

CFH DMBT1

1.16e-047702EFO_0802873
Diseasecomplement factor H measurement

CFH CFHR1 CFHR2

1.28e-0441703EFO_0008097
Diseasecomplement factor H-related protein 5 measurement

CFH CFHR1 CFHR2

1.37e-0442703EFO_0008098
Diseaseatypical hemolytic-uremic syndrome (is_implicated_in)

CFH CFHR1

1.54e-048702DOID:0080301 (is_implicated_in)
DiseaseDCN1-like protein 5 measurement

CFH ZPR1

1.98e-049702EFO_0801520
DiseaseAtypical hemolytic-uremic syndrome

CFH CFHR1

1.98e-049702cv:C2931788
DiseaseHemolytic-uremic syndrome

CFH CFHR1

1.98e-049702cv:C0019061
Diseaseleukocyte immunoglobulin-like receptor subfamily A member 5 measurement

CFH CFHR1

1.98e-049702EFO_0801766
DiseaseAtypical Hemolytic Uremic Syndrome

CFH CFHR1

2.47e-0410702C2931788
Diseasecytochrome p450 3a4 measurement

CFH ZPR1

3.01e-0411702EFO_0020303
Diseasehemopexin measurement

CFH CFHR1

3.01e-0411702EFO_0008149
Diseasecomplement factor H-related protein 1 measurement

CFH CFHR1 CFHR2

3.24e-0456703EFO_0600054
Diseasealkaline phosphatase measurement

CFHR1 TMEM106B RHPN2 IST1 ZNF318 DMBT1 ECI1 DCT NUP160

6.45e-041015709EFO_0004533
Diseasecholesteryl ester 16:1 measurement

IGFBP5 ZPR1

6.52e-0416702EFO_0010342
DiseaseChild Behaviour Checklist assessment

TENM4 TENM3

8.28e-0418702EFO_0005661
DiseaseAge-related macular degeneration

CFH CFHR1

8.28e-0418702cv:C0242383
Diseasecomplement factor H-like 1 protein measurement

CFH TMEM106B

1.24e-0322702EFO_0600092
Diseasemyocardial infarction

TMEM106B TENM3 ZPR1 DMBT1 ADGRL3

1.47e-03350705EFO_0000612
Diseasecholesteryl ester 14:0 measurement

CFH ZPR1

1.87e-0327702EFO_0010340

Protein segments in the cluster

PeptideGeneStartEntry
QECRNGSLYVRDNTG

CTC1

126

Q2NKJ3
LNNYEIRNGRLLGVC

A1CF

116

Q9NQ94
SGEYLSNCVQIIDRG

ADGRL3

1211

Q9HAR2
IGGIARTYTDQCVQI

AP4B1

371

Q9Y6B7
LQGICKRNIRNIYGE

ANKRD61

376

A6NGH8
LYQLEGNKRITCRNG

CFH

1141

P08603
QNCDRIRTGQGSIYL

DNHD1

481

Q96M86
DYEQLRVRCLQSGTL

CAPN1

41

P07384
VYQECTQLSGNRDVL

MPEG1

381

Q2M385
YCQERGAEIATTGQL

BCAN

276

Q96GW7
LNQYAIVLCRTEQGT

FRAS1

2581

Q86XX4
QSRLEQCRLEGYNSL

KAZN

756

Q674X7
YGCLNRQIRGELSKQ

GPR61

341

Q9BZJ8
CNNRLYITGGRDEKN

KLHL6

556

Q8WZ60
TQQATEGYAGIRCEN

DST

161

Q03001
YLQRCGEQVDSVELG

LRRC75A

196

Q8NAA5
VGDTGERLLYNCRNN

LOXHD1

581

Q8IVV2
QIKERLQSCYQGEGN

PLXNA2

366

O75051
QSGQRGYECVLNIQG

PLXNA2

731

O75051
QSGQRGYECILNIQG

PLXNA4

731

Q9HCM2
GYECILNIQGSEQRV

PLXNA4

736

Q9HCM2
QRGLVLRNESCSENY

PFKP

631

Q01813
GYELQGREQLTCTQE

TPO

771

P07202
EGDTVQIICNTGYRL

CFHR2

106

P36980
LGGQQCYRLISVEQE

MEGF8

2436

Q7Z7M0
GRGVCLNEKSYREQV

IGFBP5

96

P24593
YGRLEEKGCNIRTQS

PLA2G5

71

P39877
DIYCQGALVLGQSLR

GYG2

46

O15488
RGGNEQCLRYIANLI

GLYATL3

171

Q5SZD4
RYCIGLNETQLGIIA

ECI1

171

P42126
ENIQRLAGRDTLYSC

DOCK11

1176

Q5JSL3
INGRQNTLRCEVSGI

FSTL4

816

Q6MZW2
EQVSRLAALCYRQGV

LDHD

76

Q86WU2
GLESRESQSQYCRNI

GCNT3

41

O95395
ARRCITGGIVEEYQL

BMPR1A

441

P36894
YTEESINNGGIECLR

ADCY3

936

O60266
VCERTTDRYVALQNG

MARK1

506

Q9P0L2
EYGKLCRTNQIGTVN

IST1

131

P53990
RAGRQGQAITLVTQY

DDX49

341

Q9Y6V7
SICIYGGRNRNGQIE

DDX53

326

Q86TM3
NGGRTVECYVVERRQ

IGFN1

671

Q86VF2
EGDTVQIICNTGYRL

CFHR1

106

Q03591
VNGSDRCQGRVEVLY

DMBT1

736

Q9UGM3
VELNVGGQVYVTRRC

KCTD12

36

Q96CX2
AATGIQRNRTVCYDL

P2RY6

166

Q15077
EALQQTELYCRARGL

PLA2G4D

681

Q86XP0
CLTYNNGRLRNLISD

POLR1E

316

Q9GZS1
NLITSLREQCYGERG

RTP1

156

P59025
VDCGRNTTYQLGQSE

TMEM106B

251

Q9NUM4
TLRCQGGQETQEYRL

LILRB1

46

Q8NHL6
RGCTYETQLQLSARE

SH2D5

251

Q6ZV89
QCVNGDSRVELRSYV

PLEKHA7

971

Q6IQ23
LSAQLRYCGRNVIEN

OR56A3

166

Q8NH54
IQELRRGSQAANIYC

WDR45B

221

Q5MNZ6
EVRTLRGLEKQGNCY

NUP160

1111

Q12769
LYTQIGTRCDRQTQA

RHPN2

226

Q8IUC4
ICQRNYVTVESGRRL

TOP3B

521

O95985
CIRLANRTIVEGYAN

VPS50

851

Q96JG6
QSAGRIQDQGVRYTL

ZPR1

91

O75312
RIVLQGDNRSYSQEG

TEX13D

526

A0A0J9YY54
YGRINTCQRLLQDIS

TRPA1

456

O75762
TGQVVQEGTRRYRLC

ZBTB8A

351

Q96BR9
LNGYCRLNSVQVLER

KCTD15

221

Q96SI1
LIRCIVEYQNKGRGN

SS18L2

31

Q9UHA2
LQNEGFTCTIRYRQI

TENM4

2046

Q6N022
QITQDCRYEVQLGGS

STAB1

66

Q9NY15
GDLFLNGQTCRIVQR

STAB2

1851

Q8WWQ8
RQGQNFTLRQLGVCE

TENM3

76

Q9P273
NLQSDGFICTIRYRQ

TENM3

1981

Q9P273
NYTGRIRLDIQGTGQ

PIGR

186

P01833
VTLCNGTYEGLLRRN

DCT

296

P40126
GIGCNLDSQRLQYII

UEVLD

316

Q8IX04
YRKTRIGGLQDQECI

EDA2R

91

Q9HAV5
SQCSRGLERYISQEE

ZNF318

196

Q5VUA4
NVLRGGQEVKYEQCS

WNK3

96

Q9BYP7
DYVIQTTRNGVRLCL

NAPSA

341

O96009
RGRYQVITNGGQCEA

MYBPC2

416

Q14324